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https://www.readbyqxmd.com/read/29345847/characterizing-the-temporal-evolution-of-the-hepatitis-c-virus-epidemic-in-pakistan
#1
Houssein H Ayoub, Zaina Al Kanaani, Laith J Abu-Raddad
Pakistan has the second largest number of hepatitis C virus (HCV) infections in the world. We assessed past, present, and future levels and trends of the HCV epidemic in Pakistan. An age-structured mathematical model was developed and analyzed to describe transmission dynamics over 1980-2050. The model was fitted to a nationally-representative survey and a comprehensive database of systematically-gathered HCV antibody (Ab) prevalence data. HCV Ab and chronic infection prevalences peaked at 5.3% and 3.9% in 2000, but were projected to decline to 4...
January 18, 2018: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29344031/age-period-cohort-analysis-of-obesity-and-overweight-in-iranian-children-and-adolescents
#2
Mostafa Hosseini, Roya Kelishadi, Masoud Baikpour, Neamatollah Ataei, Mostafa Qorbani, Mahmoud Yousefifard, Ramin Heshmat, Mohammad-Esmail Motlagh, Behnaz Bazargani, Arash Abbasi, Kazem Mohammad
Background: To date, few studies looked upon obesity and overweight in children and adolescents through the 3 different temporal dimensions of age, period, and cohort. The current study aimed at evaluating the trends of these health issues among children under 19 years old using the age-period-cohort (APC) analysis. Methods: Data gathered through 5 cross sectional studies including 2 national health surveillance (1990 - 91 and 1999), and 3 CASPIAN surveys (2003, 2009, and 2011)...
October 2017: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29343989/comparison-of-the-performance-of-five-screening-methods-for-sarcopenia
#3
Médéa Locquet, Charlotte Beaudart, Jean-Yves Reginster, Jean Petermans, Olivier Bruyère
Background: Sarcopenia leads to serious adverse health consequences. There is a dearth of screening tools for this condition, and performances of these instruments have rarely been evaluated. Our aim was to compare the performance of five screening tools for identifying elders at risk of sarcopenia against five diagnostic definitions. Subjects and methods: We gathered cross-sectional data of elders from the SarcoPhAge ("Sarco"penia and "Ph"ysical Impairment with Advancing "Age") study...
2018: Clinical Epidemiology
https://www.readbyqxmd.com/read/29326015/ecchymosis-and-or-haematoma-formation-after-prophylactic-administration-of-subcutaneous-enoxaparin-in-the-abdomen-or-arm-of-the-critically-ill-patient
#4
R Jareño-Collado, M M Sánchez-Sánchez, M P Fraile-Gamo, N García-Crespo, S Barba-Aragón, H Bermejo-García, R Sánchez-Izquierdo, E I Sánchez-Muñoz, A López-López, S Arias-Rivera
INTRODUCTION: Ecchymosis and/or haematoma are the most common adverse events after subcutaneous administration of low molecular weight heparin. There is no strong recommendation as to the puncture site. OBJECTIVE: To evaluate the adverse events, ecchymosis and/or haematoma after the administration of prophylactic subcutaneous enoxaparin in the abdomen vs the arm in the critically ill patient. METHODOLOGY: A randomised, two-arm clinical trial (injection in the abdomen vs the arm), performed between July 2014 and January 2017, in an 18-bed, polyvalent intensive care unit...
January 8, 2018: Enfermería Intensiva
https://www.readbyqxmd.com/read/29317302/bu-shen-tong-luo-decoction-prevents-bone-loss-via-inhibition-of-bone-resorption-and-enhancement-of-angiogenesis-in-ovariectomy-induced-osteoporosis-of-rats
#5
Han Yuan, Linyan Xiao, Wen Min, Wenchao Yuan, Shengfeng Lu, Guicheng Huang
ETHNOPHARMACOLOGICAL RELEVANCE: Gathering three ancient formulas, traditional Chinese medicine Bu-Shen-Tong-Luo decoction (BSTLD) has been used to treat postmenopausal osteoporosis (PMO) at the Jiangsu Province Hospital of Chinese Medicine for decades. However, the effect of BSTLD on angiogenesis and bone resorption as well as its possible mechanism are still unknown. AIM OF THE STUDY: This study was aimed to evaluate the preventive effect of BSTLD on ovariectomy-induced bone loss and vasculature disorder, and to investigate the possible bone protection mechanism of BSTLD in inhibiting bone resorption by enhancing angiogenesis signaling in ovariectomy-induced osteoporosis of rats...
January 6, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29306415/revealing-cooperative-binding-of-polycationic-cyclodextrins-with-dna-oligomers-by-capillary-electrophoresis-coupled-to-mass-spectrometry
#6
Cédric Przybylski, Juan M Benito, Véronique Bonnet, Carmen Ortiz Mellet, José M García Fernández
Gene delivery is critical for the development of nucleic acid-based therapies against a range of severe diseases. The conception of non-viral (semi)synthetic vectors with low cytotoxicity and virus-like efficiency is gathering a lot of efforts, but it represents a fantastic challenge still far from accomplishment. Carbohydrate-based scaffolds offer interesting features towards this end, such as easy availability, relatively cheap cost, tuning properties and a good biocompatibility. The lack of analytical methods providing quantitative and qualitative data on their binding properties with oligonucleotides (DNA/RNA), with a minimal time and sample consumption, represents a limitation for these channels...
March 9, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29305018/multilevel-analysis-of-individual-heterogeneity-and-discriminatory-accuracy-maihda-within-an-intersectional-framework
#7
Juan Merlo
BACKGROUND: Analyzing Body Mass Index as a didactical example, the study by Evans, Williams, Onnela, and Subramanian (EWOS study) introduce a novel methodology for the investigation of socioeconomic disparities in health. By using multilevel analysis to model health inequalities within and between strata defined by the intersection of multiple social and demographic dimensions, the authors provide a better understanding of the health heterogeneity existing in the population. Their innovative methodology allows for gathering inductive information on a large number of stratum-specific interactions of effects and, simultaneously, informs on the discriminatory accuracy of such strata for predicting individual health...
December 26, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29297740/impact-of-a-mass-gathering-alcohol-sobering-facility-on-emergency-resources
#8
Franco Castro-Marin, Steven A Maher, Tomas Navarro, Tomas Nuño, John Whitney, Andrew McDonald, Albert Razo, Christopher Marcuzzo, Russell Chick, Joshua B Gaither
OBJECTIVE: Alcohol consumption has been implicated as an important factor driving the demand for medical care at mass gatherings. Patients exhibiting signs of possible alcohol intoxication are frequently diverted from traditional medical support facilities located within mass gathering events due to their disruptive behavior or need for prolonged observation. This conventional strategy can place additional stress on Emergency Medical Services (EMS) and Emergency Department (ED) resources...
January 3, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29287699/from-mass-gatherings-medicine-to-mass-gatherings-health-conclusions-from-the-3rd-international-conference-on-mass-gatherings-medicine-riyadh-kingdom-of-saudi-arabia
#9
EDITORIAL
S Yezli, A Assiri, H Nabulsi, A Awam, L Blumberg, T Endericks, A Stergachis, S Reicher, B McCloskey, E Petersen, B Alotaibi
No abstract text is available yet for this article.
January 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29279887/regional-variation-of-computed-tomographic-imaging-in-the-united-states-and-the-risk-of-nephrectomy
#10
H Gilbert Welch, Jonathan S Skinner, Florian R Schroeck, Weiping Zhou, William C Black
Importance: While computed tomography (CT) represents a tremendous advance in diagnostic imaging, it also creates the problem of incidental detection-the identification of tumors unrelated to the clinical symptoms that initiate the test. Objective: To determine the geographic variation in the United States in CT imaging and the corresponding association with one of the most consequential sequelae of incidental detection: nephrectomy. Design, Setting, and Participants: This study is a cross-sectional analysis of age-, sex-, and race-adjusted Medicare data (January 2010-December 2014) from 306 hospital referral regions (HRRs) in the United States and includes information from 15 million fee-for-service Medicare beneficiaries age 65 to 85 years...
December 26, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29249943/the-suprachiasmatic-nucleus-of-the-dromedary-camel-camelus-dromedarius-cytoarchitecture-and-neurochemical-anatomy
#11
Khalid El Allali, Mohamed R Achaâban, Mohammed Piro, Mohammed Ouassat, Etienne Challet, Mohammed Errami, Nouria Lakhdar-Ghazal, André Calas, Paul Pévet
In mammals, biological rhythms are driven by a master circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Recently, we have demonstrated that in the camel, the daily cycle of environmental temperature is able to entrain the master clock. This raises several questions about the structure and function of the SCN in this species. The current work is the first neuroanatomical investigation of the camel SCN. We carried out a cartography and cytoarchitectural study of the nucleus and then studied its cell types and chemical neuroanatomy...
2017: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/29248685/bioconversion-of-carbon-dioxide-to-methane-using-hydrogen-and-hydrogenotrophic-methanogens
#12
REVIEW
Jana Zabranska, Dana Pokorna
Biogas produced from organic wastes contains energetically usable methane and unavoidable amount of carbon dioxide. The exploitation of whole biogas energy is locally limited and utilization of the natural gas transport system requires CO2 removal or its conversion to methane. The biological conversion of CO2 and hydrogen to methane is well known reaction without the demand of high pressure and temperature and is carried out by hydrogenotrophic methanogens. Reducing equivalents to the biotransformation of carbon dioxide from biogas or other resources to biomethane can be supplied by external hydrogen...
December 14, 2017: Biotechnology Advances
https://www.readbyqxmd.com/read/29229084/serological-study-of-bordetella-pertussis-mycoplasma-pneumonia-and-chlamydia-pneumonia-in-iranian-hajj-pilgrims-with-prolonged-cough-illnesses-a-follow-up-study
#13
Masoud Rahimian, Mahdi HosseiniB
INTRODUCTION: Hajj pilgrimage is the biggest and longest mass gathering in the Muslim world. Annually, about 50% of more than 2.5 million pilgrims participating in this ritual get involved in severe devastating coughs. Most coughs continue, so the pilgrims turn back home and transmit them to family members and other people. Despite the high prevalence of coughs for many years, what causes them remains unknown. Considering the pertussis-like clinical picture of the so-called "hajj coughs", the researchers conducted a study to measure antibodies against three known common atypical bacteria, namely Bordetella Pertussis, Chlamydia Pneumonia and Mycoplasma Pneumonia...
November 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/29228785/an-overview-on-indications-and-chemical-composition-of-aromatic-waters-hydrosols-as-functional-beverages-in-persian-nutrition-culture-and-folk-medicine-for-hyperlipidemia-and-cardiovascular-conditions
#14
Azadeh Hamedi, Seyed Mahmoud Moheimani, Amirhossein Sakhteman, Hamed Etemadfard, Mahmoodreza Moein
Hydrosol beverages in Persian nutrition culture and ethnomedicine are the side products of essential oil industry that are used as delicious drinks or safe remedies. To investigate indications and chemical composition of hydrosol beverages for hyperlipidemia and cardiovascular conditions, Fars province was selected as the field of study. Ethnomedical data were gathered by questionnaires. The constituents of hydrosols were extracted with liquid/liquid extraction and analyzed by gas chromatography-mass spectrometry...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/29227598/event-medicine-pearls-and-pitfalls-of-managing-mass-gatherings
#15
Brian Higgins, Jared McKinney
No abstract text is available yet for this article.
May 2017: JEMS: a Journal of Emergency Medical Services
https://www.readbyqxmd.com/read/29226434/protein-identification-in-imaging-mass-spectrometry-through-spatially-targeted-liquid-micro-extractions
#16
Daniel J Ryan, David Nei, Boone M Prentice, Kristie L Rose, Richard M Caprioli, Jeffrey M Spraggins
RATIONALE: Liquid extraction surface analysis (LESA) can be used to generate spatially-directed protein identifications in an imaging mass spectrometry (IMS) workflow. This approach involves the use of robotic micro-extractions coupled to online liquid chromatography (LC). We have characterized the extraction efficiency of this method as well as its ability to identify proteins from a matrix assisted laser/desorption ionization (MALDI) IMS experiment. METHODS: Proteins and peptides were extracted from transverse sections of a rat brain and sagittal sections of a mouse pup using liquid surface extractions...
December 10, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/29219139/a-point-source-outbreak-of-acute-gastroenteritis-among-school-students-in-kerala-india
#17
P S Rakesh, Rajeswaran Thiagesan, Rakesh Ramachandran
An outbreak investigation was initiated following an outbreak of acute gastroenteritis among schoolchildren in Kottarakara. Steps included active search for cases at schools, describing the outbreak in terms of person, place, and time, generating hypothesis based on the findings from descriptive study, environmental observations, and testing the hypothesis using a case-control design. The final line list consisted of 871 children from different schools who attended a Republic Day parade. Having consumed the lemon juice near railway station (odds ratio [OR] 29...
October 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/29214043/folic-acid-level-and-preterm-birth-among-sudanese-women
#18
Manal E Sharif, Ahmed Mohamedain, AbdelBagi A Ahmed, Abubakr M Nasr, Ishag Adam
Background: Preterm birth (PTB) is the major health problem world-wide; there are few published studies on PTB and folic acid. Methods: The study was conducted to assess the serum level of folic acid in PTB. A case-control study was conducted at Saad Abualila maternity hospital (Khartoum, Sudan) during the period of March through December 2015. Women who delivered live singleton babies were dived in two groups; the cases were women who had PTB "delivery before completed 37weeks but after 24 weeks of pregnancy" and the controls were women who delivered at term (37-42 weeks)...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/29210007/bilateral-is-superior-to-unilateral-varicocelectomy-in-infertile-males-with-left-clinical-and-right-subclinical-varicocele-a-prospective-randomized-controlled-study
#19
Xiao-Lei Sun, Jiu-Lin Wang, Yun-Peng Peng, Qing-Qiang Gao, Tao Song, Wen Yu, Zhi-Peng Xu, Yun Chen, Yu-Tian Dai
PURPOSE: The purpose of this study is to compare the effect of bilateral versus unilateral varicocelectomy on seminal response and spontaneous pregnancy rates in infertile male patients with left clinical and right subclinical varicocele. METHODS: A total of 358 infertile men with left clinical and right subclinical varicocele were randomized to group that underwent bilateral (n = 179) and group that underwent unilateral microsurgical subinguinal varicocelectomy (n = 179)...
December 5, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/29206569/application-of-miniature-heart-rate-data-loggers-for-use-in-large-free-moving-decapod-crustaceans-method-development-and-validation
#20
Iain J McGaw, S Clay Steell, Travis E Van Leeuwen, Erika J Eliason, Steven J Cooke
Cardiovascular responses of decapod crustaceans to environmental challenges have received extensive attention. However, nearly all of these studies have been restricted to lab-based experiments; here we describe a methodology that will enable measurement of heart rate (HR) in free-moving decapods in the field. Data storage tag heart rate and temperature loggers (DST micro-HRT; Star-Oddi) were used to record electrocardiograms (ECG) and HR in large decapod crustaceans. These loggers were originally designed for use in vertebrates and must be surgically implanted in the body cavity near the heart in order to function...
January 2018: Physiological and Biochemical Zoology: PBZ
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