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https://www.readbyqxmd.com/read/27932291/influenza-not-mers-cov-among-returning-hajj-and-umrah-pilgrims-with-respiratory-illness-kashmir-north-india-2014-15
#1
Parvaiz A Koul, Hyder Mir, Siddhartha Saha, Mandeep S Chadha, Varsha Potdar, Marc-Alain Widdowson, Renu B Lal, Anand Krishnan
BACKGROUND: The increasing reports of Middle East Respiratory Syndrome (MERS) caused by MERS coronavirus (MERS-CoV) from many countries emphasize its importance for international travel. Muslim pilgrimages of Hajj and Umrah involve mass gatherings of international travellers. We set out to assess the presence of influenza and MERS-CoV in Hajj/Umrah returnees with acute respiratory infection. . METHODS: Disembarking passengers (n = 8753) from Saudi Arabia (October 2014 to April 2015) were interviewed for the presence of respiratory symptoms; 977 (11%) reported symptoms and 300 (age 26-90, median 60 years; 140 male) consented to participate in the study...
December 5, 2016: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/27929104/microneedles-with-controlled-bubble-sizes-and-drug-distributions-for-efficient-transdermal-drug-delivery
#2
Qi Lei Wang, Dan Dan Zhu, Xu Bo Liu, Bo Zhi Chen, Xin Dong Guo
Drug loaded dissolving microneedles (DMNs) fabricated with water soluble polymers have received increasing attentions as a safe and efficient transdermal drug delivery system. Usually, to reach a high drug delivery efficiency, an ideal drug distribution is gathering more drugs in the tip or the top part of DMNs. In this work, we introduce an easy and new method to introduce a bubble with controlled size into the body of DMNs. The introduction of bubbles can prevent the drug diffusion into the whole body of the MNs...
December 8, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27928973/development-of-a-mass-gathering-triage-tool-an-australian-perspective
#3
Matt Cannon, Rebecca Roitman, Jamie Ranse, Julia Morphet
Many health service organizations deploy first responders and health care professionals to mass gatherings to assess and manage injuries and illnesses. Patient presentation rates (PPRs) to on-site health services at a mass gathering range from 0.48-170 per 10,000 participants. Transport to hospital rates (TTHRs) range from 0.035-15 per 10,000 participants. The aim of this report was to outline the current literature pertaining to mass-gathering triage and to describe the development of a mass-gathering triage tool for use in the Australian context by first responders...
December 8, 2016: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/27911936/serum-calcium-magnesium-zinc-and-copper-levels-in-sudanese-women-with-preeclampsia
#4
Abdelmageed Elmugabil, Hamdan Z Hamdan, Anas E Elsheikh, Duria A Rayis, Ishag Adam, Gasim I Gasim
BACKGROUND: Although the exact pathophysiology of preeclampsia is not fully understood, several elemental micronutrient abnormalities have been suggested to play a contributory role in preeclampsia. AIMS: To investigate the levels of calcium, magnesium, zinc and copper in women with preeclampsia. SUBJECTS AND METHODS: A case-control study was conducted in Omdurman Maternity Hospital, Sudan, during the period of September through December 2014...
2016: PloS One
https://www.readbyqxmd.com/read/27908924/excess-weight-as-a-risk-factor-common-to-many-cancer-sites-words-of-caution-when-interpreting-meta-analytic-evidence
#5
Melina Arnold, Andrew G Renehan, Graham A Colditz
For over a decade, excess body weight, commonly categorized as overweight (body mass index, BMI: 25.0 to 29.9 kg/m2) and obesity (BMI: ≥ 30 kg/m2) has been an established incidence risk factor for several adult cancers (1). For 2012, the burden of disease attributed to elevated BMI was estimated as nearly half-million new cancers worldwide, making this the third highest ranked cancer risk factor globally after smoking and infections (ranked second in most western populations) and an important public health problem (2, 3)...
December 1, 2016: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/27906762/complications-in-postmastectomy-breast-reconstruction-one-year-outcomes-of-the-mastectomy-reconstruction-outcomes-consortium-mroc-study
#6
Edwin G Wilkins, Jennifer B Hamill, Hyungjin M Kim, John Y Kim, Richard J Greco, Ji Qi, Andrea L Pusic
OBJECTIVE: In postmastectomy reconstruction, procedure choice is heavily influenced by the relative risks of the various options. This study sought to evaluate complications in a large, multicenter patient population. SUMMARY OF BACKGROUND DATA: Previous studies have reported widely varying complication rates, but have been limited by their single center designs and inadequate controlling for confounders in their analyses. METHODS: Eleven sites enrolled women undergoing first time, immediate, or delayed reconstruction following mastectomy for cancer treatment or prophylaxis...
November 30, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27879668/structure-functional-basis-of-ion-transport-in-sodium-calcium-exchanger-ncx-proteins
#7
REVIEW
Moshe Giladi, Reut Shor, Michal Lisnyansky, Daniel Khananshvili
The membrane-bound sodium-calcium exchanger (NCX) proteins shape Ca(2+) homeostasis in many cell types, thus participating in a wide range of physiological and pathological processes. Determination of the crystal structure of an archaeal NCX (NCX_Mj) paved the way for a thorough and systematic investigation of ion transport mechanisms in NCX proteins. Here, we review the data gathered from the X-ray crystallography, molecular dynamics simulations, hydrogen-deuterium exchange mass-spectrometry (HDX-MS), and ion-flux analyses of mutants...
November 22, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27870880/how-simple-hypothetical-choice-experiments-can-be-utilized-to-learn-humans-navigational-escape-decisions-in-emergencies
#8
Milad Haghani, Majid Sarvi, Zahra Shahhoseini, Maik Boltes
How humans resolve non-trivial tradeoffs in their navigational choices between the social interactions (e.g., the presence and movements of others) and the physical factors (e.g., spatial distances, route visibility) when escaping from threats in crowded confined spaces? The answer to this question has major implications for the planning of evacuations and the safety of mass gatherings as well as the design of built environments. Due to the challenges of collecting behavioral data from naturally-occurring evacuation settings, laboratory-based virtual-evacuation experiments have been practiced in a number of studies...
2016: PloS One
https://www.readbyqxmd.com/read/27853041/prevalence-and-risk-factors-of-hypertension-and-diabetes-in-the-katkari-tribe-of-coastal-maharashtra
#9
M G Deo, P V Pawar, S R Kanetkar, S V Kakade
BACKGROUND AND OBJECTIVES: Urban and rural India are both going through health epidemiological transition and will soon face huge burden of noncommunicable diseases (NCDs). Information on the status of NCDs in tribals is limited. Although the prevalence of hypertension in scheduled tribes (STs) has been studied in several states by the National Nutrition Monitoring Bureau, tribe-specific data are very scanty. The objective of this study was to generate data on the status of hypertension and diabetes, the two objectively measurable NCDs in Katkaris, the dominant ST in the Raigad district of coastal Maharashtra...
November 16, 2016: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/27851816/human-disturbance-during-early-life-impairs-nestling-growth-in-birds-inhabiting-a-nature-recreation-area
#10
Carolina Remacha, Juan Antonio Delgado, Mateja Bulaic, Javier Pérez-Tris
Nature recreation conflicts with conservation, but its impacts on wildlife are not fully understood. Where recreation is not regulated, visitors to natural areas may gather in large numbers on weekends and holidays. This may increase variance in fitness in wild populations, if individuals whose critical life cycle stages coincide with periods of high human disturbance are at a disadvantage. We studied nestling development of blue tits (Cyanistes caeruleus) in a natural area where recreation activities intensify during weekends and other public holidays at picnic and leisure facilities, but not in the surrounding woods...
2016: PloS One
https://www.readbyqxmd.com/read/27848902/the-impact-of-mass-gathering-on-the-burden-of-multidrug-resistant-mycobacterium-tuberculosis-in-al-madinah-al-monawarah-region-saudi-arabia
#11
Mogahid Elhassan, Hassan A Hemeg, Miskelyemen A Elmekki, Khalid A Turkistani, Ahmed A Abdul-Aziz
BACKGROUND: The pattern of Mycobacterium tuberculosis susceptibility to first line drugs and multidrug resistance in Al-Madinah Al-Munawarah, a seasonally overcrowded are during Hajj and Omrah, is not well studied. OBJECTIVE: This study aimed to investigate anti-TB drug resistance and its distribution among new cases in Al-Madinah Al-Monawarah. METHODS: Study subjects included 622 patients with first time confirmed TB referred to the central tuberculosis laboratory in Al-Madinah between January 2012 and December 2014...
November 15, 2016: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/27837454/diabetes-and-hypertension-in-marshallese-adults-results-from-faith-based-health-screenings
#12
Pearl Anna McElfish, Brett Rowland, Christopher R Long, Jonell Hudson, Michelle Piel, Bill Buron, Sheldon Riklon, Williamina Ioanna Bing, T Scott Warmack
BACKGROUND: The Pacific Islander population in the USA is growing rapidly. However, research on Pacific Islanders in the USA is limited, or sometimes misleading due to aggregation with Asian Americans. This project seeks to add to the dearth of health literature by conducting a health assessment of Marshallese in northwest Arkansas. METHODS: Using a community-based participatory research approach, nine health screening events were conducted at local Marshallese churches...
November 11, 2016: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/27833335/the-role-of-dentistry-in-disaster-management-and-victim-identification-an-overview-of-challenges-in-indo-nepal-scenario
#13
REVIEW
Shubha Ranjan Dutta, Purnima Singh, Deepak Passi, Don Varghese, Sarang Sharma
BACKGROUND: Recently, natural disasters and terrorist activities have been leading to mass casualty situations unexpectedly around the globe. In addition to the traditional emergency medical services centering around medically trained and paramedic personnel, dental practitioners having vital skills and attributes may be important in responding to a mass casualty situation. OBJECTIVE: This paper aims at discussing the role of dentists in disaster management and the role of forensic odontology in the disaster victim identification (DVI), its status in India and some suggestions to develop the plans for same...
December 2016: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/27831795/erratum-mass-gatherings-and-the-spread-of-respiratory-infections-lessons-from-the-hajj
#14
(no author information available yet)
No abstract text is available yet for this article.
November 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/27828968/manufacturing-of-a-secretoneurin-drug-delivery-system-with-self-assembled-protamine-nanoparticles-by-titration
#15
Bernhard Scheicher, Cornelia Lorenzer, Katrin Gegenbauer, Julia Partlic, Fritz Andreae, Alexander H Kirsch, Alexander R Rosenkranz, Oliver Werzer, Andreas Zimmer
Since therapeutic peptides and oligonucleotides are gathering interests as active pharmaceutical ingredients (APIs), nanoparticulate drug delivery systems are becoming of great importance. Thereby, the possibility to design drug delivery systems according to the therapeutic needs of APIs enhances clinical implementation. Over the last years, the focus of our group was laid on protamine-oligonucleotide-nanoparticles (so called proticles), however, the possibility to modify the size, zeta potential or loading efficiencies was limited...
2016: PloS One
https://www.readbyqxmd.com/read/27819279/concurrent-profiling-of-polar-metabolites-and-lipids-in-human-plasma-using-hilic-ftms
#16
Xiaoming Cai, Ruibin Li
Blood plasma is the most popularly used sample matrix for metabolite profiling studies, which aim to achieve global metabolite profiling and biomarker discovery. However, most of the current studies on plasma metabolite profiling focused on either the polar metabolites or lipids. In this study, a comprehensive analysis approach based on HILIC-FTMS was developed to concurrently examine polar metabolites and lipids. The HILIC-FTMS method was developed using mixed standards of polar metabolites and lipids, the separation efficiency of which is better in HILIC mode than in C5 and C18 reversed phase (RP) chromatography...
November 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27806500/assessment-of-anthropometric-indices-and-related-factors-of-secondary-school-students-in-iran-province-of-hamadan-in-2014
#17
Nahid Mohammadi, Masoud Khodaveisi, Afsar Omidi, Roya Amini, Abbass Moghimbeigi
BACKGROUND: The growth of children is a health indicator at each country and growth monitoring has a great importance. This study was done to determine the anthropometric indices of secondary school students of Hamadan. METHODS: This was a cross-sectional study. 816 girl & boy secondary school students in Hamadan selected based on cluster random multistage sampling. We gathered data through questionnaire. The status of anthropometric indices was assessed by height, weight and body mass index and then it was compared with the NCHS standards...
July 12, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27797433/anopheles-plumbeus-diptera-culicidae-in-germany-updated-geographical-distribution-and-public-health-impact-of-a-nuisance-and-vector-mosquito
#18
Eva C Heym, Helge Kampen, Marcus Fahle, Tobias L Hohenbrink, Mandy Schäfer, Dorothee E Zielke, Doreen Walther
OBJECTIVES: The aim of the present study was to map the current spatial distribution of Anopheles plumbeus in Germany, a potential vector of malaria parasites and West Nile virus. Reports of mass occurrence and nuisance connected with artificial breeding site usage by this species were analysed. METHODS: Distribution data were collected from 2011 to 2014 mainly through trapping and submissions of adult mosquito specimens to a citizen science project. In the framework of the latter, additional information was gathered on recent nuisance incidents caused by An...
October 31, 2016: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/27794253/trajectories-of-body-mass-index-change-in-first-episode-of-mania-3-year-data-from-the-systematic-treatment-optimization-program-for-early-mania-stop-em
#19
Chen Hu, Ivan J Torres, Hong Qian, Hubert Wong, Priyanka Halli, Taj Dhanoa, Sharon Ahn, Gang Wang, David J Bond, Raymond W Lam, Lakshmi N Yatham
BACKGROUND: Overweight/obesity is common in patients with bipolar disorder (BD). However, little is known about longitudinal trends in body mass index (BMI) in patients with BD. Furthermore, most studies on the association between BMI and clinical outcomes are restricted by retrospective and cross-sectional designs. This study uses prospectively-gathered data from a first episode mania (FEM) cohort to examine the trajectories of BMI change and analyze their association with clinical outcomes during a 3-year period...
October 11, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27788528/factors-associated-with-knee-stiffness-following-surgical-management-of-multiligament-knee-injuries
#20
Jessica Hanley, Robert Westermann, Shane Cook, Natalie Glass, Ned Amendola, Brian R Wolf, Matthew Bollier
Postoperative knee stiffness can influence outcomes following operative treatment of multiligament knee injuries (MLKIs). The purpose of this study was to evaluate patient and surgical factors that may potentially contribute to stiffness following surgery for MLKIs. All surgically managed MLKIs involving two or more ligaments over a 10-year period at a single level one trauma center were included in this study. A retrospective review was performed to gather objective data related to the development of knee stiffness after surgery...
October 27, 2016: Journal of Knee Surgery
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