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https://www.readbyqxmd.com/read/28530591/optimization-of-an-organic-yogurt-based-on-sensorial-nutritional-and-functional-perspectives
#1
Ariadne Roberto Karnopp, Katherine Guimarães Oliveira, Eriel Forville de Andrade, Bruna Mara Postingher, Daniel Granato
The effects of purple grape juice (PGJ), grape skin flour (GSF), and oligofructose (OLI) on proximate composition, total phenolic content (TPC), antioxidant activity (AA), sensory, physicochemical, and textural properties of yogurts were analyzed using response surface methodology. Multiple regression models were proposed and results showed that PGJ increased the viscosity, AA, and TPC, while GSF increased the ash and total fiber contents of yogurts. GSF and OLI increased the hardness and consistency. A simultaneous optimization was performed to maximize TPC, ash and fibers contents, and sensory acceptance: a yogurt containing 1...
October 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28530567/using-combined-optimization-gc-ms-and-analytical-technique-to-analyze-the-germination-effect-on-phenolics-dietary-fibers-minerals-and-gaba-contents-of-kodo-millet-paspalum-scrobiculatum
#2
Seema Sharma, Dharmesh C Saxena, Charanjit S Riar
A central composite rotatable design was applied to study the effects of soaking time, germination time and temperature on the responses; total phenolics, total flavonoids and antioxidant activity for the biochemical enhancement of bioactive components of Kodo millet. The optimum conditions for producing germinated Kodo millet flour of highest TPC (83.01mgGAE/100g), TFC (87.53mgRUE/g) and AoxA (91.34%), were soaking time (13.81h), germination temperature (38.75°C) and germination time (35.82h). Protein increased significantly form, 6...
October 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28516056/simultaneous-micronization-and-purification-of-bioactive-fraction-by-supercritical-antisolvent-technology
#3
Stevanus Hiendrawan, Bambang Veriansyah, Edward Widjojokusumo, Raymond R Tjandrawinata
Simultaneous micronization and purification of DLBS3233 bioactive fraction, a combination of two Indonesian herbals Lagerstroemia speciosa and Cinnamomum burmannii has been successfully performed via supercritical anti-solvent (SAS) technology. The objective of the present study was to investigate the effectiveness of SAS technology to micronize and reduce coumarin content of DLBS3233. The effects of four SAS process parameters, i.e. pressure, temperature, concentration and solution flow rate on particle formation were investigated...
April 2017: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/28515384/physicochemical-and-antioxidant-properties-of-rice-bran-oils-produced-from-colored-rice-using-different-extraction-methods
#4
Sukanya Mingyai, Aikkarach Kettawan, Khongsak Srikaeo, Riantong Singanusong
This study investigated the physicochemical and antioxidant properties of rice bran oil (RBO) produced from the bran of three rice varities; Khao Dawk Mali 105 (white rice), Red Jasmine rice (red rice) and Hom-nin rice (black rice) using three extraction methods including cold-press extraction (CPE), solvent extraction (SE) and supercritical CO2 extraction (SC-CO2). Yields, color, acid value (AV), free fatty acid (FFA), peroxide value (PV), iodine value (IV), total phenolic compound (TPC), γ-oryzanol, α-tocopherol and fatty acid profile were analyzed...
May 17, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28505111/effects-of-mead-wort-heat-treatment-on-the-mead-fermentation-process-and-antioxidant-activity
#5
Sławomir Czabaj, Joanna Kawa-Rygielska, Alicja Z Kucharska, Jarosław Kliks
The effects of mead wort heat treatment on the mead fermentation process and antioxidant activity were tested. The experiment was conducted with the use of two different honeys (multiflorous and honeydew) collected from the Lower Silesia region (Poland). Heat treatment was performed with the use of a traditional technique (gently boiling), the more commonly used pasteurization, and without heat treatment (control). During the experiment fermentation dynamics were monitored using high performance liquid chromatography with refractive index detection (HPLC-RID)...
May 14, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28504713/elevated-pttg-and-pbf-predicts-poor-patient-outcome-and-modulates-dna-damage-response-genes-in-thyroid-cancer
#6
M L Read, J C Fong, B Modasia, A Fletcher, W Imruetaicharoenchoke, R J Thompson, H Nieto, J J Reynolds, A Bacon, U Mallick, A Hackshaw, J C Watkinson, K Boelaert, A S Turnell, V E Smith, C J McCabe
The proto-oncogene PTTG and its binding partner PBF have been widely studied in multiple cancer types, particularly thyroid and colorectal, but their combined role in tumourigenesis is uncharacterised. Here, we show for the first time that together PTTG and PBF significantly modulate DNA damage response (DDR) genes, including p53 target genes, required to maintain genomic integrity in thyroid cells. Critically, DDR genes were extensively repressed in primary thyrocytes from a bitransgenic murine model (Bi-Tg) of thyroid-specific PBF and PTTG overexpression...
May 15, 2017: Oncogene
https://www.readbyqxmd.com/read/28498617/segmental-resection-is-a-safe-oncologic-alternative-to-total-proctocolectomy-in-elderly-patients-with-ulcerative-colitis-and-malignancy
#7
Nabeel Khan, Elisabeth Cole, Yash Shah, Emily Carter Paulson
AIM: The standard approach for the surgical management for colorectal cancer (CRC) in the setting of ulcerative colitis (UC) involves total proctocolectomy (TPC). However, some patients also undergo a partial resection (PR). This may be an attractive option in older patients with a high for surgery. The aim of this study is to compare the risk of metachronous cancer after PR or TPC for CRC in the setting of UC. METHOD: This was a retrospective cohort study conducted through the Nationwide Veterans Affairs Healthcare System (VA)...
May 12, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28496481/evaluation-of-various-biological-activities-of-the-aerial-parts-of-scrophularia-frigida-growing-in-iran
#8
Parina Asgharian, Fariba Heshmati Afshar, Solmaz Asnaashari, Farzaneh Lotfipour, Behzad Baradaran, Elmira Zolali, Elhameh Nikkhah, Abbas Delazar
The current study was assigned to evaluate the total phenol, total flavonoid content (TPC, TFC) and antioxidant properties of extracts from the aerial parts of Scrophularia frigida (S. frigida). Extracts were also tested by preliminary phytochemical screening as well as cytotoxic activity against Artemia salina, MCF-7 (human breast carcinoma) and SW-480 (colon carcinoma) and L-929 (normal) cell lines along with antimicrobial characteristic. DPPH, MTT and Brine shrimp lethality tests and disc diffusion method were carried out to determine the biological activities of the different extracts of S...
2017: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/28494614/evaluation-of-pigments-from-methanolic-extract-of-tagetes-erecta-and-beta-vulgaris-as-antioxidant-and-antibacterial-agent
#9
Mariya Saani, Reena Lawrence, Kapil Lawrence
The Total Phenolic Content (TPC), antioxidant and antibacterial activities of methanolic extract of Marigold flower (MF) (Tagetes erecta) and Beet root (BR) (Beta vulgaris) were examined. The present work reveals that MF contained greater amount of TPC (42.5 mg/g GAE) as compared to BR (39.4 mg/g GAE). Methanolic extract of MF exhibited excellent DPPH free radical scavenging power (IC50 0.0716 mg/mL) and reducing power at 1 mg/mL concentration. Similar results have been obtained in FTC and TBA method. The results of antibacterial test indicated that the methanolic extract of MF and BR is significantly effective against both type of Gram-negative (Escherichia coli, Shigella dysenteriae) and Gram-positive (Bacillus subtilis, Staphylococcus aureus) bacterial strains...
May 11, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28494096/physicochemical-properties-and-antioxidant-capacity-of-chinese-olive-canarium-album-l-cultivars
#10
Qiang Chang, Ming-Hua Su, Qing-Xi Chen, Bi-Yu Zeng, Hui-Hua Li, Wei Wang
In this study, the physicochemical characteristics and antioxidant potentials of 10 Chinese olive cultivars were investigated. Considerable differences were found between cultivars in weight, edible yield, water content, size, shape, total soluble solids, and total titratable acidity. The major sugars and organic acids in all the cultivars were glucose, fructose, and malic acid. Phenolics were the most abundant antioxidants (1174.0 to 1799.6 mg gallic acid equivalents/100 g fresh weight). Twelve phenolic compounds were identified and quantified by UPLC-MS/MS...
May 11, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28492621/leaf-parts-from-greek-artichoke-genotypes-as-a-good-source-of-bioactive-compounds-and-antioxidants
#11
Spyridon A Petropoulos, Carla Pereira, Lillian Barros, Isabel C F R Ferreira
Globe artichoke is an important vegetable in the Mediterranean diet. However, the marketable part of the plant constitutes a small portion of its total crop biomass and large amounts of waste are produced during its cultivation. In this study, the phenolic compound content and composition and the antioxidant activity of leaf parts [blades (SLB), petioles and midribs (SPM)] from various Greek artichoke genotypes were evaluated. The results showed significant variation in antioxidant activities and bioactive compound contents between the studied genotypes, with the leaf blades of most of the genotypes having a high content of flavonoids (mainly luteolin glycoside derivatives), which ranged between 49 and 78% of total phenolic compounds (TPC)...
May 11, 2017: Food & Function
https://www.readbyqxmd.com/read/28490191/proliferative-and-antioxidant-activity-of-symphytum-officinale-root-extract
#12
Ireneusz Sowa, Roman Paduch, Maciej Strzemski, Sylwia Zielińska, Ewelina Rydzik-Strzemska, Jan Sawicki, Ryszard Kocjan, Janusz Polkowski, Adam Matkowski, Michał Latalski, Magdalena Wójciak-Kosior
The root of Symphytum officinale L. is commonly used in folk medicine to promote the wound healing, reduce the inflammation and in the treatment of broken bones. The objective of our investigation was to analyse the extract from S. officinale in term of its antioxidant activity and the effect on cell viability and proliferation of human skin fibroblast (HSF). Moreover, the quantification of main phenolics and allantoin was conducted using HPLC-DAD method. Five compounds were found: rosmarinic, p-hydroxybenzoic, caffeic, chlorogenic and p-coumaric acid...
May 10, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28490120/evaluation-of-antioxidant-potential-of-artocarpus-heterophyllus-l-j33-variety-fruit-waste-from-different-extraction-methods-and-identification-of-phenolic-constituents-by-lcms
#13
Mohd Nazrul Hisham Daud, Dian Nashiela Fatanah, Noriham Abdullah, Rohaya Ahmad
Artocarpus heterophyllus J33 (AhJ33) fruit is a popular and valuable jackfruit variety in Malaysia. For export, the pulp has to be separated from the skin which is usually discarded. Hence, the conversion of the fruit waste to food products with economic value needs to be explored utilizing the waste to wealth concept. This paper reports the evaluation of antioxidant potential of AhJ33 fruit waste (rind and rachis) extracts from three different extraction methods (maceration, percolation and Soxhlet). The antioxidant potential was assessed by DPPH radical scavenging, FRAP and β-carotene bleaching assays...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28490078/characterization-of-phenolic-compounds-in-chia-salvia-hispanica-l-seeds-fiber-flour-and-oil
#14
Sheila Cristina Oliveira-Alves, Débora Barbosa Vendramini-Costa, Cinthia Baú Betim Cazarin, Mário Roberto Maróstica Júnior, João Pedro Borges Ferreira, Andreia Bento Silva, Marcelo Alexandre Prado, Maria Rosário Bronze
The consumption of chia seeds products has increased recently and it has been suggested that the inclusion of this functional food in a daily human diet could contribute to improve consumers' health. However, a better knowledge about the composition of these products is mandatory. In this work, the phenolic compounds from commercial samples of chia seed, fiber flour and oil were extracted using an ultrasound-assisted methodology and were separated and identified by high-performance liquid chromatography coupled to a mass spectrometer...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28486558/temperature-during-conidiation-affects-stress-tolerance-pigmentation-and-trypacidin-accumulation-in-the-conidia-of-the-airborne-pathogen-aspergillus-fumigatus
#15
Daisuke Hagiwara, Kanae Sakai, Satoshi Suzuki, Myco Umemura, Toshihiko Nogawa, Naoki Kato, Hiroyuki Osada, Akira Watanabe, Susumu Kawamoto, Tohru Gonoi, Katsuhiko Kamei
Asexual spores (conidia) are reproductive structures that play a crucial role in fungal distribution and survival. As fungal conidia are, in most cases, etiological agents of plant diseases and fungal lung disease, their stress resistance and interaction with their hosts have drawn increasing attention. In the present study, we investigated whether environmental temperature during conidiation affects the stress tolerance of the conidia of the human pathogenic fungus Aspergillus fumigatus. Conidia from a 25°C culture showed a lower tolerance to heat (60°C) and oxidative (H2O2) stresses and a marked resistance to ultraviolet radiation exposure, compared with those produced at 37 and 45°C...
2017: PloS One
https://www.readbyqxmd.com/read/28484130/humeral-fracture-in-a-japanese-black-calf-repaired-by-closed-approach-and-two-methods-of-external-skeletal-fixation
#16
Norio Yamagishi, Ayano Kajiwara, Ken-Ichi Shibano, Takahiro Aoki, Megumi Itoh, Kaoru Hatate, Kimie Iino
A healthy 71-day-old female Japanese Black calf was evaluated for fracture of the left humerus. The left humeral fracture was treated by closed repair and unilateral external skeletal fixation (ESF) with an epoxy putty fixator. The calf was active, and eight days after surgery slipped and fell, resulting in breakage of the ESF. The calf underwent repair by transfixation pinning and casting (TPC), which is an alternative to the ESF method. The TPC was removed 37 days after the first surgery, and the calf could bear weight on the left forelimb while walking...
May 7, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28479730/anti-hepatocarcinogenic-and-anti-oxidant-effects-of-mangrove-plant-scyphiphora-hydrophyllacea
#17
Sameera R Samarakoon, Chanthirika Shanmuganathan, Meran K Ediriweera, Poorna Piyathilaka, Kamani H Tennekoon, Ira Thabrew, Prasanna Galhena, E Dilip De Silva
CONTEXT: Scyphiphora hydrophyllacea is a shrub mangrove plant of the family Rubiaceae and not yet been studied for anti-hepatocarcinogenic effects. OBJECTIVES: We investigated possible in vitro anti-hepatocarcinogenic and antioxidant properties of S. hydrophyllacea. MATERIALS AND METHODS: Dried leaves of S. hydrophyllacea were sequentially extracted into hexane, chloroform, ethyl acetate, and methanol and tested for cytotoxicity on HepG2 cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and sulforhodamine B assays, and for antioxidant activities by the free radical 1,1-diphenyl-2-picryl-hydrazyl (DPPH) and 2,2'-azino-bis-3-ethylbenzthiazoline-6-sulfonic acid (ABTS) assays...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28460948/enzymatic-biotransformation-of-polyphenolics-increases-antioxidant-activity-of-red-and-white-grape-pomace
#18
Isabela M Martins, Bruna S Roberto, Jeffrey B Blumberg, C-Y Oliver Chen, Gabriela A Macedo
Grape pomace (GP) is a polyphenolic-rich byproduct of wine production. As most polyphenolics are either bound to cellular matrices or present as free polymeric forms, treatment with hydrolytic enzymes may act to increase GP functionalities. The aim of this study was to examine the impact of tannase alone (T), pectinase plus cellulase (PC) or a mixture of them (TPC) on the hydrolysis of polyphenolics in red GP (RGP), white GP (WGP), and mixed GP (MGP) from Brazilian wine production, as well as antioxidant activity of the products...
November 2016: Food Research International
https://www.readbyqxmd.com/read/28450931/cell-penetrating-peptide-of-sodium-iodide-symporter-effect-on-the-i-131-radiotherapy-on-thyroid-cancer
#19
Yi-Xiang Fan, Zhi-Xin Liang, Qing-Zhu Liu, Han Xiao, Ke-Bin Li, Ji-Zhen Wu
The aim of the present study was to clarify whether the cell penetrating peptide of sodium-iodide symporter (NIS) has an effect on the I-131 radiotherapy of thyroid cancer. Firstly, we combined the HIV-1 TAT peptide (a cell penetrating peptide, dTAT) and established a nanoparticle vector (dTAT NP) to study the delivery efficiency of this cell-penetrating strategy for tumor-targeted gene delivery. dTAT NP was transfected into cultured TPC-1 cells as a model to study the effects of I-131 radiotherapy on thyroid cancer...
March 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28449992/effect-of-incorporating-finger-millet-in-wheat-flour-on-mixolab-behavior-chapatti-quality-and-starch-digestibility
#20
Bharati Sharma, Hardeep Singh Gujral, Vicky Solah
Wheat and finger millet flour (two cultivars) were blended in the ratio (3:1) to form a composite flour and its dough properties were studied on the mixolab. The chapatti making and digestibility behavior of the composite flour was also investigated. The wheat finger millet (WFM) flour blend displayed up to 30.7% higher total phenolic content (TPC), 38.2% higher total flavonoid content (TFC) and 75.4% higher antioxidant activity (AOA) than the wheat flour. Chapattis prepared from the composite blends exhibited lower retrogradation as evident by the mixolab retrogradation index, higher values of soluble starch and soluble amylose in stored chapatti...
September 15, 2017: Food Chemistry
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