keyword
MENU ▼
Read by QxMD icon Read
search

TPC

keyword
https://www.readbyqxmd.com/read/28102295/bioactive-compounds-and-antioxidant-activity-of-wolfberry-infusion
#1
Yujing Sun, Japaer Rukeya, Wenyang Tao, Peilong Sun, Xingqian Ye
An infusion of the wolfberry (Lycium barbarum L.) is a traditional Asian herbal tea. This is the most commonly consumed form of dried wolfberry worldwide, yet little scientific information on wolfberry infusions is available. We investigated the effects of making infusions with hot water on the color, the content of bioactive compounds (polysaccharides, polyphenols, flavonoids and carotenoids) and the antioxidant ability of wolfberry infusions. The contents of bioactive compounds and the antioxidant activity of a wolfberry infusion increased with increased infusion temperature and time...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28098872/trim29-promotes-progression-of-thyroid-carcinoma-via-activating-p13k-akt-signaling-pathway
#2
Jinkai Xu, Zongyu Li, Qinghua Su, Jun Zhao, Jiancang Ma
Thyroid cancer (TC) is a common malignancy of the endocrine system. Abnormal expression of tripartite motif-containing 29 (TRIM29) has been reported to promote tumorigenesis and predict poor prognosis in several human malignancies. The aim of this study was to assess the involvement of TRIM29 in the significance and prognosis of TC. Fifty-six tumor samples and their clinicopathological para-meters were obtained from TC patients; the expression level of TRIM29 was detected by RT-qPCR and western blotting. TRIM29 expression was knocked down by small interfering RNA (siRNA) among TT, TPC-1, and K1 cells to investigate the biological role of TRIM29 in TC cells...
January 13, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28096396/tuning-the-ion-selectivity-of-two-pore-channels
#3
Jiangtao Guo, Weizhong Zeng, Youxing Jiang
Organellar two-pore channels (TPCs) contain two copies of a Shaker-like six-transmembrane (6-TM) domain in each subunit and are ubiquitously expressed in plants and animals. Interestingly, plant and animal TPCs share high sequence similarity in the filter region, yet exhibit drastically different ion selectivity. Plant TPC1 functions as a nonselective cation channel on the vacuole membrane, whereas mammalian TPC channels have been shown to be endo/lysosomal Na(+)-selective or Ca(2+)-release channels. In this study, we performed systematic characterization of the ion selectivity of TPC1 from Arabidopsis thaliana (AtTPC1) and compared its selectivity with the selectivity of human TPC2 (HsTPC2)...
January 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28071022/research-on-the-effect-of-culture-time-on-the-kombucha-tea-beverage-s-antiradical-capacity-and-sensory-value
#4
Anna Gramza-Michałowska, Bartosz Kulczyński, Yuan Xindi, Małgorzata Gumienna
BACKGROUND: Recent consumption trends shows high consumer acceptability and growing medicinal interest in the biological value of kombucha tea. This tea is a sweetened tea leaf brew fermented with a layer containing mainly acetic acid bacteria, yeast and lactic acid bacteria. The main antioxidants in tea leaves are polyphenols, the consumption of which is proven to be beneficial for human health, e.g. protecting from reactive oxygen species (ROS). The aim of the present research was to evaluate antiradical activity, total polyphenol content (TPC) and sensory value of kombucha tea brews...
October 2016: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/28071020/the-effect-of-microwave-roasting-on-the-antioxidant-properties-of-the-bangladeshi-groundnut-cultivar
#5
Abbas Ali, Anowarul Islam, Tarun K Pal
BACKGROUND: Groundnut seeds are an important source of bioactive phenolic compounds with noteworthy antioxidant capacity, which may be enhanced by the microwave roasting process. The aim of this work is   to study the changes in antioxidant activity in groundnut seeds during microwave roasting, as a function of roasting time and extract concentration, in order to maximise the phenolic content and antioxidant activity of roasted seeds. METHODS: The study was conducted to evaluate total phenolic content (TPC), total flavonoid content (TFC), and antioxidative activity of methanolic (GME), ethanolic (GEE), and chloroform (GCE) extracts and methanolic extract of oil (GMO) from groundnut seeds exposed to microwaves...
October 2016: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/28071019/influence-of-different-extraction-conditions-on-antioxidant-properties-of-soursop-peel
#6
Wei Zin Lee, Sui Kiat Chang, Hock Eng Khoo, Chiaw Mei Sia, Hip Seng Yim
BACKGROUND: Soursop is a healthy fruit. Peels form about 20% of the soursop fruit and are usually discarded as waste product. With a view to utilizing soursop peel as a source of valuable compounds, this study aimed to investigate the influence of different extraction conditions on total phenolic content (TPC) and antioxidant capacity (AC) of soursop (Annona muricata L.) peel. METHODS: Different ethanol concentrations (20-100%, v/v), extraction temperatures (25- 60°C), and extraction time (1-5 h) were tested...
October 2016: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/28071018/effect-of-roasting-degree-on-the-antioxidant-activity-of-different-arabica-coffee-quality-classes
#7
Božana Odžaković, Natalija Džinić, Zoran Kukrić, Slavica Grujić
BACKGROUND: Coffee is one of the most widely consumed beverages in the world, because of its unique sensory properties and physiological properties. Coffee beverages represent a significant source of antioxidants in the consumers' diet and contribute significantly to their daily intake. The aim of this research was to investigate the effect of different roasting degrees on the content of biologically active compounds and antioxidant activity in different quality classes of Arabica coffee...
October 2016: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/28071008/microwave-assisted-extraction-of-phenolic-compounds-from-polygonum-multiflorum-thunb-roots
#8
Le Pham Tan Quoc, Nguyen Van Muoi
BACKGROUND: The aim of this study was to determine the best extraction conditions for total phenolic content (TPC) and antioxidant capacity (AC) of Polygonum multiflorum Thunb. root using microwave-assisted extraction (MAE). METHODS: The raw material used was Polygonum multiflorum Thunb. root powder. Five factors such as solvent type, solvent concentrations, solvent/material ratio, extraction time and microwave power were studied; TPC and AC values were determined by the Folin-Ciocalteu method and DPPH free radical scavenging activity measurement, respectively...
April 2016: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/28070587/highly-selective-colorimetric-detection-of-cyanide-anions-in-aqueous-media-by-triphenylamine-and-phenanthro-9-10-d-imidazole-based-probes
#9
Arockiam Jesin Beneto, Ayyanar Siva
Two novel fluorescent probes based on triphenylamine (TPC) and phenanthro(9,10-d-imidazole) (PITP) have been synthesized and studied as cyanide selective indicators in aqueous media. Complete colour bleaching was observed due to the nucleophilic addition of cyanide to the 2-vinylmalononitrile of TPC, which results in the disruption of the extended conjugation and turns off the intramolecular charge transfer (ICT) process. Furthermore, a visible color change was observed with a large Stokes shift (108 nm) upon the addition of cyanide anions to PITP, due to the formation of hydrogen bonding between the CN(-) anion and -NH of PITP, which increased the electron density on the donor moiety and induced strong ICT...
January 10, 2017: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/28070317/prevention-of-microbial-hazard-on-fresh-cut-lettuce-through%C3%A2-adoption-of-food-safety-and-hygienic-practices-by%C3%A2-lettuce-farmers
#10
Lateefah A Oyinlola, Adewale O Obadina, Adebukunola M Omemu, Olusola B Oyewole
Lettuce is consumed raw in salads and is susceptible to microbial contamination through environment, agricultural practices, and its morphology, thus, a potential vehicle for food-borne illness. This study investigated the effect of adoption of food safety and hygienic practices by lettuce farmers on the microbial safety of field sourced lettuce in Lagos State, Nigeria. Ten structured questionnaires were administered randomly to 10 lettuce farmers to assess food safety and hygienic practices (FSH). Two farmers who practice FSH and two farmers who do not practice NFSH were finally used for this study...
January 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28064427/biochemical-and-molecular-study-of-carpobrotus-edulis-bioactive-properties-and-their-effects-on-dugesia-sicula-turbellaria-tricladida-regeneration
#11
Emna Meddeb, Mohamed Charni, Tesnime Ghazouani, Autilia Cozzolino, Florinda Fratianni, Faten Raboudi, Filomena Nazzaro, Sami Fattouch
The traditional medicinal properties of Carpobrotus edulis are well recognized, particularly in Tunisia where it is used for wound healing. Thus, in this study, biochemical and molecular properties of its leaves' bioactive aqueous-acetone extract were investigated. The total phenolic content (TPC) of the extract was estimated to be 184 ± 5 mg/100 g of fresh matter (FM). The qualitative and quantitative polyphenolic profile was determined by ultra performance liquid chromatography with diode array detection (UPLC-DAD) and showed that chlorogenic acid was the major compound (43...
January 7, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28060486/highly-porous-rigid-rod-polyamide-aerogels-with-superior-mechanical-properties-and-unusually-high-thermal-conductivity
#12
Jarrod C Williams, Baochau N Nguyen, Linda McCorkle, Daniel Scheiman, Justin S Griffin, Stephen A Steiner, Mary Ann B Meador
We report here the fabrication of polyamide aerogels composed of poly-p-phenylene-terephthalamide, the same backbone chemistry as DuPont's Kevlar. The all-para-substituted polymers gel without the use of cross-linker and maintain their shape during processing-an improvement over the meta-substituted cross-linked polyamide aerogels reported previously. Solutions containing calcium chloride (CaCl2) and para-phenylenediamine (pPDA) in N-methylpyrrolidinone (NMP) at low temperature are reacted with terephthaloyl chloride (TPC)...
January 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28055974/glutamate-induces-autophagy-via-the-two-pore-channels-in-neural-cells
#13
Gustavo J S Pereira, Manuela Antonioli, Hanako Hirata, Rodrigo P Ureshino, Aline R Nascimento, Claudia Bincoletto, Tiziana Vescovo, Mauro Piacentini, Gian Maria Fimia, Soraya S Smaili
NAADP (nicotinic acid adenine dinucleotide phosphate) has been proposed as a second messenger for glutamate in neuronal and glial cells via the activation of the lysosomal Ca2+ channels TPC1 and TPC2. However, the activities of glutamate that are mediated by NAADP remain unclear. In this study, we evaluated the effect of glutamate on autophagy in astrocytes at physiological, non-toxic concentration. We found that glutamate induces autophagy at similar extent as NAADP. By contrast, the NAADP antagonist NED-19 or SiRNA-mediated inhibition of TPC1/2 decreases autophagy induced by glutamate, confirming a role for NAADP in this pathway...
December 31, 2016: Oncotarget
https://www.readbyqxmd.com/read/28041560/effect-of-extraction-process-on-composition-oxidative-stability-and-rheological-properties-of-purslane-seed-oil
#14
Sasan Delfan-Hosseini, Kooshan Nayebzadeh, Leila Mirmoghtadaie, Maryam Kavosi, Seyede Marzieh Hosseini
Purslane seed oil could be considered as potential nutritious oil due to its desirable fatty acid composition and other biological active compounds. In this study the effect of three extraction procedure including solvent extraction, cold pressing and microwave pretreatment (MW) followed by cold pressing on oil yield, physicochemical properties, oxidative stability and rheological behaviors of oil was investigated. Solvent extracted oil had the highest extraction yield (72.31%). Pretreatment by microwave before cold press extraction resulted in an increase in extraction yield, total phenolic compound (TPC) and antioxidant activity...
May 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28035161/composition-bioactive-compounds-and-antioxidant-activity-of-common-indian-fruits-and-vegetables
#15
Jatinder Pal Singh, Amritpal Kaur, Khetan Shevkani, Narpinder Singh
The present work was undertaken to evaluate the chemical composition (proximate, minerals and dietary fibre), colour parameters, antioxidant activity and polyphenol profiles of different fruits (pomegranate, kinnow, mango, banana, jambolan, grapes and sapodilla) and vegetables (beetroot, brinjal, orange carrot, bitter gourd, mentha and spinach). The amount of insoluble dietary fibre was higher than soluble dietary fibre for all fruits and vegetables. Vegetables showed superior mineral composition (higher amounts of K, Ca and Fe) as compared to fruits...
November 2016: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28033160/substance-p-in-flush-tears-and-schirmer-strips-of-healthy-participants
#16
Maria Markoulli, Moneisha Gokhale, Jingjing You
PURPOSE: To determine the repeatability of the flush tear collection technique and the Schirmer strip for Substance P tear analysis. METHODS: The tears of 10 healthy non-contact-lens wearers were collected via Schirmer strip and microcapillary following instillation of either 20 μL (F-20) or 60 μL (F-60) of saline. Each technique was conducted on two occasions and in a randomized order. Total protein content (TPC) and Substance P concentrations were determined...
December 29, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28011620/wnt5a-drives-an-invasive-phenotype-in-human-glioblastoma-stem-like-cells
#17
Elena Binda, Alberto Visioli, Fabrizio Giani, Nadia Trivieri, Orazio Palumbo, Silvia Restelli, Fabio Dezi, Tommaso Mazza, Caterina Fusilli, Federico Legnani, Massimo Carella, Francesco DiMeco, Rohit Duggal, Angelo Luigi Vescovi
Brain invasion by glioblastoma (hGBM) determines prognosis, recurrence and lethality in patients, but no master factor coordinating the invasive properties of GBM has been identified. Here we report evidence favouring such a role for the non-canonical WNT family member Wnt5a. We found the most invasive gliomas to be characterized by Wnt5a overexpression, which correlated with poor prognosis and also discriminated infiltrating mesenchymal GBM from poorly motile proneural and classical GBM. Indeed, Wnt5a overexpression associated with tumor-promoting stem-like characteristics (TPC) in defining the character of highly-infiltrating mesenchymal GBM cells (Wnt5aHigh)...
December 23, 2016: Cancer Research
https://www.readbyqxmd.com/read/28010811/using-gamm-to-examine-inter-individual-heterogeneity-in-thermal-performance-curves-for-natrix-natrix-indicates-bet-hedging-strategy-by-mothers
#18
Mathew J Vickers, Fabien Aubret, Aurélie Coulon
The thermal performance curve (TPC) illustrates the dependence on body- and therefore environmental- temperature of many fitness-related aspects of ectotherm ecology and biology including foraging, growth, predator avoidance, and reproduction. The typical thermal performance curve model is linear in its parameters despite the well-known, strong, non-linearity of the response of performance to temperature. In addition, it is usual to consider a single model based on few individuals as descriptive of a species-level response to temperature...
January 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/28000845/long-non-coding-rna-neat1-promotes-malignant-progression-of-thyroid-carcinoma-by-regulating-mirna-214
#19
Jian-Hua Li, Su-Qin Zhang, Xing-Guang Qiu, Shui-Jun Zhang, Shou-Hua Zheng, Dan-Hua Zhang
The long non‑coding RNA nuclear enrich abundant transcript 1 (NEAT1) has been identified to be carcinogenic in various cancers and elevated NEAT1 expression was tightly linked to tumorigenesis and progression. However, the mechanism has not been revealed in progression of thyroid cancer. Tumor xenograft mouse model was established and tumor size was evaluated. Arg‑1, NEAT1 and miR‑214 expression in CBMs, TAMs, BMDMs and RAW 264.7 cell lines were detected. TPC‑1 cells were subjected to si‑NEAT1 transfection in vitro for cell viability study...
February 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/27999608/anticancer-activity-antioxidant-activity-and-phenolic-and-flavonoids-content-of-wild-tragopogon-porrifolius-plant-extracts
#20
Fuad Al-Rimawi, Suzi Rishmawi, Sharehan H Ariqat, Mahmoud F Khalid, Ismail Warad, Zaidoun Salah
Tragopogon porrifolius, commonly referred to as white salsify, is an edible herb used in folk medicine to treat cancer. Samples of Tragopogon porrifolius plant grown wild in Palestine were extracted with different solvents: water, 80% ethanol, and 100% ethanol. The extracts were analyzed for their total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity (AA). Four different antioxidant assays were used to evaluate AA of the extracts: two measures the reducing power of the extracts (ferric reducing antioxidant power (FRAP) and cupric reducing antioxidant power (CUPRAC)), while two other assays measure the scavenging ability of the extracts (2,2-azino-di-(3-ethylbenzothialozine-sulphonic acid (ABTS)) and 2,2-diphenyl-1-picrylhydrazyl (DPPH))...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
keyword
keyword
14193
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"