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https://www.readbyqxmd.com/read/28806786/an-economic-evaluation-of-vector-control-in-the-age-of-a-dengue-vaccine
#1
Christopher Fitzpatrick, Alexander Haines, Mathieu Bangert, Andrew Farlow, Janet Hemingway, Raman Velayudhan
INTRODUCTION: Dengue is a rapidly emerging vector-borne Neglected Tropical Disease, with a 30-fold increase in the number of cases reported since 1960. The economic cost of the illness is measured in the billions of dollars annually. Environmental change and unplanned urbanization are conspiring to raise the health and economic cost even further beyond the reach of health systems and households. The health-sector response has depended in large part on control of the Aedes aegypti and Ae...
August 14, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28805637/wolbachia-mediated-virus-blocking-in-the-mosquito-vector-aedes-aegypti
#2
REVIEW
Gerard Terradas, Elizabeth A McGraw
Viruses transmitted by mosquitoes such as dengue, Zika and West Nile cause a threat to global health due to increased geographical range and frequency of outbreaks. The bacterium Wolbachia pipientis may be the solution reducing disease transmission. Though commonly missing in vector species, the bacterium was artificially and stably introduced into Aedes aegypti to assess its potential for biocontrol. When infected with Wolbachia, mosquitoes become refractory to infection by a range of pathogens, including the aforementioned viruses...
August 2017: Current Opinion in Insect Science
https://www.readbyqxmd.com/read/28803981/first-report-of-coelomomyces-santabrancae-sp-nov-blastocladiomycetes-blastocladiales-infecting-mosquito-larvae-diptera-culicidae-in-central-brazil
#3
M E Rueda-Páramo, C Montalva, W Arruda, É K K Fernandes, C Luz, R A Humber
A project from 2013-2017 to discover pathogenic fungi and oomycetes from dipteran species that are vectors of major diseases of humans and animals in central Brazil and to begin evaluating the potential of these pathogens as potential biological control agents concentrated on mosquito larvae. Some collecting sites proved to be especially productive for pathogens of naturally occurring mosquito species and for placements of healthy sentinel larvae of Aedes aegypti in various sorts of containers in a gallery forest in the Santa Branca Ecoturismo Private Reserve of Natural Patrimony (RPPN) near Terezópolis de Goiás (GO)...
August 10, 2017: Journal of Invertebrate Pathology
https://www.readbyqxmd.com/read/28802513/nonconvulsive-status-epilepticus-after-electroconvulsive-therapy-a-review-of-literature
#4
Awais Aftab, Ashley VanDercar, Ayham Alkhachroum, Christine LaGrotta, Keming Gao
BACKGROUND: The clinical presentation and risk factors of nonconvulsive status epilepticus (NCSE) in the context of electroconvulsive therapy (ECT) are poorly understood, and guidance regarding diagnosis and management remains scarce. In this article, we identify case reports of ECT-induced NCSE from literature, and discuss the presentation, diagnosis, and management of these cases in the context of what is known about NCSE from the neurology literature. METHODS: A literature search on PubMed for case reports of NCSE after ECT...
July 15, 2017: Psychosomatics
https://www.readbyqxmd.com/read/28800547/dinuclear-silver-i-n-heterocyclic-carbene-complexes-synthesis-characterization-and-larvicidal-activity-of-bis-imidazolium-dinuclear-silver-i-n-heterocyclic-carbene-complexes
#5
Puvana D Selvarajoo, Rosenani A Haque, Umie F M Haziz, Silas W Avicor, Mustafa F F Wajidi, Mohd R Razali
New synthesized bis-imidazolium salts that are linked by xylyl derivatives moiety, 1-4 was reacted with Ag2O to facilitate the formation of dinuclear Ag(I)-N-heterocyclic carbene (NHC) complexes, 5-8, respectively. All the synthesized ligand salts and complexes were characterized by (1)H and (13)C NMR, FTIR spectroscopy and elemental analysis. Molecular structures of compounds 3, 5, and 7 were elucidated by single crystal X-ray diffraction analyses. Larvicidal studies against the Aedes aegypti and Culex quinquefasciatus were carried out on all synthesized compounds following the World Health Organization standard larval susceptibility test...
August 4, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28800427/sibling-response-to-initial-antiepileptic-medication-predicts-treatment-success
#6
Keisuke Ueda, Fatema Serajee, Jan Rajlich, Sharief Taraman, Lindsey Steckling, Ahm M Huq
OBJECTIVE: A recent study focusing on a response to antiepileptic drugs (AED) among siblings for epilepsy showed a similar response among epileptic siblings to specific AEDs or AED combinations. Currently, however, family history of treatment response to AEDs is not readily employed in deciding which initial medication to use when treating patients with epilepsy. We tested the hypothesis that sibling response to initial AED predicts treatment success. METHODS: Presumed siblings were identified from a single-center database of patients diagnosed with epilepsy by matching last name, address, and name of parent(s)...
August 1, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28799517/imaging-biomarkers-of-anti-epileptic-drug-action-insights-from-magnetic-resonance-imaging
#7
Lorenzo Caciagli, Fenglai Xiao, Britta Wandschneider, Matthias J Koepp
BACKGROUND: Approximately one third of patients with epilepsy are refractory to medical treatment. Adverse effects associated with anti-epileptic drugs (AEDs) are considered to affect quality of life often more than seizures themselves. Neuroimaging techniques, particularly magnetic resonance imaging (MRI), have proven instrumental in clinical decision making in relation to epilepsy surgery, but may also provide further insights into the mechanisms underlying treatment response and side effects associated with AEDs...
August 9, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28798803/preparation-of-a-nanoemulsion-with-carapa-guianensis-aublet-meliaceae-oil-by-a-low-energy-solvent-free-method-and-evaluation-of-its-preliminary-residual-larvicidal-activity
#8
Flávia L M Jesus, Fernanda B de Almeida, Jonatas L Duarte, Anna E M F M Oliveira, Rodrigo A S Cruz, Raimundo N P Souto, Ricardo M A Ferreira, Regina Gendzelevski Kelmann, José C T Carvalho, Ana C Lira-Guedes, Marcelino Guedes, Conxita Solans, Caio P Fernandes
Andiroba (Carapa guianensis) seeds are the source of an oil with a wide range of biological activities and ethnopharmacological uses. However, few studies have devoted attention to innovative formulations, including nanoemulsions. The present study aimed to obtain a colloidal system with the andiroba oil using a low-energy and organic-solvent-free method. Moreover, the preliminary residual larvicidal activity of the nanoemulsion against Aedes aegypti was evaluated. Oleic and palmitic acids were the major fatty acids, in addition to the phytosterol β-sitosterol and limonoids (tetranortriterpenoids)...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28798323/modeling-the-transmission-and-control-of-zika-in-brazil
#9
Liping Wang, Hongyong Zhao, Sergio Muniz Oliva, Huaiping Zhu
Zika virus, a reemerging mosquito-borne flavivirus, started spread across Central and Southern America and more recently to North America. The most serious impacted country is Brazil. Based on the transmission mechanism of the virus and assessment of the limited data on the reported suspected cases, we establish a dynamical model which allows us to estimate the basic reproduction number R 0 = 2.5020. The wild spreading of the virus make it a great challenge to public health to control and prevention of the virus...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28796799/differential-outcomes-of-zika-virus-infection-in-aedes-aegypti-orally-challenged-with-infectious-blood-meals-and-infectious-protein-meals
#10
Yan-Jang S Huang, Amy C Lyons, Wei-Wen Hsu, So Lee Park, Stephen Higgs, Dana L Vanlandingham
BACKGROUND: Infection of mosquitoes is an essential step for the transmission of mosquito-borne arboviruses in nature. Engorgement of infectious blood meals from viremic infected vertebrate hosts allows the entry of viruses and initiates infection of midgut epithelial cells. Historically, the infection process of arboviruses in mosquitoes has been studied through the engorgement of mosquitoes from viremic laboratory animals or from artificial feeders containing blood mixed with viruses harvested from cell cultures...
2017: PloS One
https://www.readbyqxmd.com/read/28796789/multiple-introductions-of-the-dengue-vector-aedes-aegypti-into-california
#11
Evlyn Pless, Andrea Gloria-Soria, Benjamin R Evans, Vicki Kramer, Bethany G Bolling, Walter J Tabachnick, Jeffrey R Powell
The yellow fever mosquito Aedes aegypti inhabits much of the tropical and subtropical world and is a primary vector of dengue, Zika, and chikungunya viruses. Breeding populations of A. aegypti were first reported in California (CA) in 2013. Initial genetic analyses using 12 microsatellites on collections from Northern CA in 2013 indicated the South Central US region as the likely source of the introduction. We expanded genetic analyses of CA A. aegypti by: (a) examining additional Northern CA samples and including samples from Southern CA, (b) including more southern US populations for comparison, and (c) genotyping a subset of samples at 15,698 SNPs...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28796376/neuropsychiatric-adverse-events-of-antiepileptic-drugs-in-brain-tumour-related-epilepsy-an-italian-multicentre-prospective-observational-study
#12
C Bedetti, M Romoli, M Maschio, C Di Bonaventura, E Nardi Cesarini, P Eusebi, S Siliquini, S Dispenza, P Calabresi, C Costa
BACKGROUND AND PURPOSE: We assessed the prevalence and magnitude of neuropsychiatric adverse events (NPAEs) associated with antiepileptic drugs (AEDs) among patients with brain tumour-related epilepsy (BTRE). METHODS: This observational, prospective, multicentre study enrolled 259 patients with BTRE after neurosurgery. All patients received AED monotherapy. Efficacy was assessed through clinical diaries, whereas NPAEs were collected using the Neuropsychiatric Inventory Test-12 questionnaire at baseline and after 5 months...
August 10, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28793920/dengue-1-virus-and-vector-competence-of-aedes-aegypti-diptera-culicidae-populations-from-new-caledonia
#13
Elodie Calvez, Laurent Guillaumot, Dominique Girault, Vaea Richard, Olivia O'Connor, Tuterarii Paoaafaite, Magali Teurlai, Nicolas Pocquet, Van-Mai Cao-Lormeau, Myrielle Dupont-Rouzeyrol
BACKGROUND: Dengue virus (DENV) is the arbovirus with the highest incidence in New Caledonia and in the South Pacific region. In 2012-2014, a major DENV-1 outbreak occurred in New Caledonia. The only known vector of DENV in New Caledonia is Aedes aegypti but no study has yet evaluated the competence of New Caledonia Ae. aegypti populations to transmit DENV. This study compared the ability of field-collected Ae. aegypti from different locations in New Caledonia to transmit the DENV-1 responsible for the 2012-2014 outbreak...
August 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28793030/mosquito-species-occurrence-in-association-with-landscape-composition-in-green-urban-areas
#14
F R G Montagner, O S Silva, S M Jahnke
Aedes aegypti prefers densely populated habitats, but has been shown to explore less anthropogenic environments. We investigated composition of the abundance of mosquitoes in forested areas and assessed relationships between species occurrences and different types of land use and land cover at three spatial scales (100m, 500m and 1000m). Mosquitoes were collected from October 2012 to March 2013 using oviposition traps. We collected 4,179 mosquitoes in total including at least 10 species. Aedes albopictus and Limatus durhami were eudominant species, representing 90% of all collected individuals...
July 27, 2017: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/28793020/intelligent-monitoring-of-aedes-aegypti-in-a-rural-area-of-rio-de-janeiro-state-brazil
#15
Argemiro Sanavria, Claudia Bezerra da Silva, Érica Heleno Electo, Lidiane Cristina Rocha Nogueira, Sandra Maria Gomes Thomé, Isabele da Costa Angelo, Gilmar Ferreira Vita, Talles Eduardo Cabral Sanavria, Elisa Domingues Padua, Denise Glória Gaiotte
The aim of this research was to monitor the presence of females of Aedes aegypti (Linnaeus, 1762) on the Seropédica municipality, Rio de Janeiro State, from 2010 to 2013. For this purpose, the Intelligent Dengue Monitoring (IM-Dengue) and Intelligent Virus Monitoring (IM-Virus) developed by Universidade Federal de Minas Gerais (Ecovec - Minas Gerais, Brazil), were used. IM-Dengue is a tool that allows achieving a weekly overview of A. aegypti infestation, while IM-Virus is another tool that allows detecting dengue virus directly from the mosquito, by Real Time-PCR...
2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28792705/homocysteine-metabolism-and-hematological-parameters-in-early-stage-of-phenytoin-treated-epileptic-children
#16
Tarun K Sharma, S K Vardey, S Sitaraman
BACKGROUND: Long-term antiepileptic drug (AED) therapy has been associated with metabolic consequences that lead to an increase in risk of atherosclerosis in patients with epilepsy. Earlier published studies showed conflicting results about the levels of hematological parameters, serum homocysteine, folate, and vitamin B12, in epileptics treated with phenytoin monotherapy. Therefore, we evaluated homocysteine metabolism and hematological parameters in early stage of phenytoin treated epileptic children...
July 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28790458/zika-virus-replication-in-the-mosquito-culex-quinquefasciatus-in-brazil
#17
Duschinka Rd Guedes, Marcelo Hs Paiva, Mariana Ma Donato, Priscilla P Barbosa, Larissa Krokovsky, Sura W Dos S Rocha, Karina LA Saraiva, Mônica M Crespo, Tatiana Mt Rezende, Gabriel L Wallau, Rosângela Mr Barbosa, Cláudia Mf Oliveira, Maria Av Melo-Santos, Lindomar Pena, Marli T Cordeiro, Rafael F de O Franca, André Ls de Oliveira, Christina A Peixoto, Walter S Leal, Constância Fj Ayres
Zika virus (ZIKV) is a flavivirus that has recently been associated with an increased incidence of neonatal microcephaly and other neurological disorders. The virus is primarily transmitted by mosquito bite, although other routes of infection have been implicated in some cases. The Aedes aegypti mosquito is considered to be the main vector to humans worldwide; however, there is evidence that other mosquito species, including Culex quinquefasciatus, transmit the virus. To test the potential of Cx. quinquefasciatus to transmit ZIKV, we experimentally compared the vector competence of laboratory-reared Ae...
August 9, 2017: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/28783051/microcephaly-prevalence-in-infants-born-to-zika-virus-infected-women-a-systematic-review-and-meta-analysis
#18
REVIEW
Antonio Victor Campos Coelho, Sergio Crovella
Zika virus is an emergent flavivirus transmitted by Aedes genus mosquitoes that recently reached the Americas and was soon implicated in an increase of microcephaly incidence. The objective of the present study is to systematically review the published data and perform a meta-analysis to estimate the prevalence of microcephaly in babies born to Zika virus-infected women during pregnancy. We searched PubMed and Cochrane databases, included cohort studies, and excluded case reports and case series publications...
August 5, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28782121/rift-valley-fever-virus-and-european-mosquitoes-vector-competence-of-culex-pipiens-and-stegomyia-albopicta-%C3%A2-aedes-albopictus
#19
M Brustolin, S Talavera, A Nuñez, C Santamaría, R Rivas, N Pujol, M Valle, M Verdún, A Brun, N Pagès, N Busquets
Rift Valley fever (RVF) is a mosquito-borne disease caused by the Rift Valley fever virus (RVFV). Rift Valley fever affects a large number of species, including human, and has severe impact on public health and the economy, especially in African countries. The present study examined the vector competence of three different European mosquito species, Culex pipiens (Linnaeus, 1758) form molestus (Diptera: Culicidae), Culex pipiens hybrid form and Stegomyia albopicta (= Aedes albopictus) (Skuse, 1894) (Diptera: Culicidae)...
August 7, 2017: Medical and Veterinary Entomology
https://www.readbyqxmd.com/read/28782097/interactions-between-cannabidiol-and-commonly-used-antiepileptic-drugs
#20
Tyler E Gaston, E Martina Bebin, Gary R Cutter, Yuliang Liu, Jerzy P Szaflarski
OBJECTIVE: To identify potential pharmacokinetic interactions between the pharmaceutical formulation of cannabidiol (CBD; Epidiolex) and the commonly used antiepileptic drugs (AEDs) through an open-label safety study. Serum levels were monitored to identify interactions between CBD and AEDs. METHODS: In 39 adults and 42 children, CBD dose was started at 5 mg/kg/day and increased every 2 weeks by 5 mg/kg/day up to a maximum of 50 mg/kg/day. Serum AED levels were obtained at baseline prior to CBD initiation and at most study visits...
August 6, 2017: Epilepsia
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