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https://www.readbyqxmd.com/read/28529142/gender-differences-in-the-effects-of-cathinone-and-the-interaction-with-caffeine-on-temperature-and-locomotor-activity-in-the-rat
#1
Hadeel A Alsufyani, James R Docherty
We have investigated gender differences in the effects of cathinone and the interaction with caffeine on temperature and movement activity in Wistar rats. Telemetry probes were implanted in rats under isoflurane anaesthesia, and 7 days later, temperature and activity were recorded in conscious unrestrained animals. Caffeine (10mg/lkg) or vehicle, and 30min later, cathinone (5mg/kg) or vehicle, were injected subcutaneously. Cathinone produced significant and marked increases in activity, and the response to cathinone was significantly greater in female animals...
May 18, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28527719/involvement-of-serotonin-in-the-ventral-tegmental-area-in-thermoregulation-of-freely-moving-rats
#2
Takayuki Ishiwata, Hiroshi Hasegawa, Benjamin N Greenwood
We have recently reported that the serotonin (5-HT) projections from the midbrain's raphe nuclei that contains 5-HT cell bodies may play a role both in heat production and in heat loss. The purpose of the present study was to clarify the involvement of 5-HT in the ventral tegmental area (VTA), where 5-HT is suggested to participate in thermoregulation, using the combined methods of telemetry, microdialysis, and high performance liquid chromatography, with a special emphasis on regulation of the body temperature (Tb) in freely moving rats...
May 17, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28521325/effect-of-high-salt-diet-on-age-related-high-blood-pressure-and-hypothalamic-redox-signaling
#3
Bilgen Basgut, Melissa A Whidden, Nataliya Kirichenko, Mary Woods, Benedek Erdos, Philip J Scarpace, Nihal Tümer
AIM: The aim of this study was to investigate the effect of a high salt (HS) diet on age-related changes in blood pressure (BP) and the possible role played by regulatory central mechanisms. METHODS: Young (5 months) and old (27 months) male Fischer 344 × Brown Norway (F344/BN) rats were fed standard chow or 8% HS diet for 12 days. BP and heart rate (HR) were measured by telemetry. RESULTS: Mean arterial BP (MAP) was significantly elevated in old rats during the day and night when compared with young animals...
May 19, 2017: Pharmacology
https://www.readbyqxmd.com/read/28509764/environmental-and-physiological-factors-affect-football-head-impact-biomechanics
#4
Jason P Mihalik, Adam Z Sumrall, Susan W Yeargin, Kevin M Guskiewicz, Kevin B King, Scott C Trulock, Edgar W Shields
PURPOSE: Recent anecdotal trends suggest a disproportionate number of head injuries in collegiate football players occur during preseason football camp. In warmer climates, this season also represents the highest risk for heat-related illness among collegiate football players. Since concussion and heat illnesses share many common symptoms, we need 1) to understand if environmental conditions, body temperature, and hydration status affect head impact biomechanics; and 2) to determine if an in-helmet thermistor could provide a valid measure of gastrointestinal temperature...
May 15, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28509726/sodium-butyrate-suppresses-angiotensin-ii-induced-hypertension-by-inhibition-of-renal-pro-renin-receptor-and-intrarenal-renin-angiotensin-system
#5
Lei Wang, Qing Zhu, Aihua Lu, Xiaofen Liu, Linlin Zhang, Chuanming Xu, Xiyang Liu, Haobo Li, Tianxin Yang
OBJECTIVES: Butyrate, a short-chain fatty acid, is the end product of the fermentation of complex carbohydrates by the gut microbiota. Recently, sodium butyrate (NaBu) has been found to play a protective role in a number of chronic diseases. However, it is still unclear whether NaBu has a therapeutic potential in hypertension. The present study was aimed to investigate the role of NaBu in angiotensin II (Ang II)-induced hypertension and to further explore the underlying mechanism. METHODS: Ang II was infused into uninephrectomized Sprague-Dawley rats with or without intramedullary infusion of NaBu for 14 days...
May 13, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28506591/early-echocardiography-has-a-low-yield-in-patients-with-transient-ischemic-attack
#6
Elie Harmouche, Ghada A Mahmoud, Michael Ross, Jason Hockenberry, Robin Dharia, Fadi Nahab
STUDY OBJECTIVE: Current guidelines recommend patients presenting with transient ischemic attack (TIA) undergo echocardiography to evaluate for a cardiac source. However, echocardiography is not available daily at many centers. We assessed the yield from early transthoracic echocardiography (TTE) in consecutive patients with TIA evaluated in an emergency department observation unit (EDOU) protocol. METHODS: This observational cohort study took place in an academic medical center from January 1, 2011 to July 31, 2013...
May 11, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28504992/trends-in-perioperative-practice-and-resource-utilization-in-patients-with-obstructive-sleep-apnea-undergoing-joint-arthroplasty
#7
Crispiana Cozowicz, Jashvant Poeran, Ashley Olson, Madhu Mazumdar, Eva E Mörwald, Stavros G Memtsoudis
BACKGROUND: Emerging evidence associating obstructive sleep apnea (OSA) with adverse perioperative outcomes has recently heightened the level of awareness among perioperative physicians. In particular, estimates projecting the high prevalence of this condition in the surgical population highlight the necessity of the development and adherence to "best clinical practices." In this context, a number of expert panels have generated recommendations in an effort to provide guidance for perioperative decision-making...
May 11, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28503374/sooty-tern-onychoprion-fuscatus-survival-oil-spills-shrimp-fisheries-and-hurricanes
#8
Ryan M Huang, Oron L Bass, Stuart L Pimm
Migratory seabirds face threats from climate change and a variety of anthropogenic disturbances. Although most seabird research has focused on the ecology of individuals at the colony, technological advances now allow researchers to track seabird movements at sea and during migration. We combined telemetry data on Onychoprion fuscatus (sooty terns) with a long-term capture-mark-recapture dataset from the Dry Tortugas National Park to map the movements at sea for this species, calculate estimates of mortality, and investigate the impact of hurricanes on a migratory seabird...
2017: PeerJ
https://www.readbyqxmd.com/read/28502871/a-leadless-pacemaker-in-the-real-world-setting-the-micra-transcatheter-pacing-system-post-approval-registry
#9
Paul R Roberts, Nicolas Clementy, Faisal Al Samadi, Christophe Garweg, Jose Luis Martinez-Sande, Saverio Iacopino, Jens Brock Johansen, Xavier Vinolas Prat, Robert Kowal, Didier Klug, Lluis Mont, Jan Steffel, Shelby Li, Dirk Van Osch, Mikhael F El-Chami
BACKGROUND: First-in-man studies of leadless pacemakers have demonstrated high implant success rates, and safety and efficacy objectives were achieved. Outside of the investigational setting, there are particular concerns over cardiac effusion/perforation, device dislodgement, infection, telemetry, and battery issues. OBJECTIVE: The acute performance of the Micra transcatheter pacemaker from a worldwide post-approval registry is reported. METHODS: The registry is an ongoing prospective single-arm observational study designed to assess the safety and effectiveness of Micra in the post-approval setting...
May 11, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28500612/electric-smog-telemetry-interference-between-icd-and-lvad
#10
REVIEW
David Duncker, Thorben König, Johanna Müller-Leisse, Roman Michalski, Hanno Oswald, Jan D Schmitto, Johann Bauersachs, Christian Veltmann
Electromagnetic interferences between implantable cardioverter/defibrillators (ICD) and left ventricular assist devices (LVAD) impacting telemetry have been described in previous generations of ICD as well as LVAD, but have been predominantly overcome in current ICD generations. After introduction of a new fully magnetically levitated centrifugal continuous-flow circulatory pump, we report a case of tenacious telemetry interference between the HeartMate 3 LVAD and an ICD after battery exchange to an Iforia 5...
May 12, 2017: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/28500597/blood-pressure-monitoring-using-radio-telemetry-method-in-mice
#11
Yu Wang, Sean E Thatcher, Lisa A Cassis
The TA11PA-C10 implantable transmitter (Data Sciences International, DSI) is designed to measure blood pressure (BP) and activity in freely moving laboratory mice. The fluid filled catheter is placed in the free flowing blood of the systemic artery (inserted into the left carotid artery and extended into the aorta), and the transmitter body is placed in a benign location for long-term biocompatibility. The transmitter can be used to monitor BP in mice (as small as 17 g) under normal physiological and unrestricted conditions 24 h a day while remaining free from stress associated with human interaction...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28498076/cochlear-implantation-in-mondini-s-deformity-could-the-straight-electrode-array-with-length-of-31%C3%A2-mm-be-fully-inserted
#12
Jia-Qiang Sun, Jing-Wu Sun, Xiao-Yan Hou
CONCLUSIONS: The straight electrode array with length of 31 mm can be fully inserted using round window insertion in cochlear implantation with Mondini's deformity. It is a safe and effective process, but also a challenging task of the full implantation in children with Mondini's deformity. OBJECTIVE: The aim of this study is to discuss whether the straight electrode array with a length of 31 mm could be fully inserted in cochlear implantation with Mondini's deformity...
February 22, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28495301/2017-ishne-hrs-expert-consensus-statement-on-ambulatory-ecg-and-external-cardiac-monitoring-telemetry
#13
Jonathan S Steinberg, Niraj Varma, Iwona Cygankiewicz, Peter Aziz, Paweł Balsam, Adrian Baranchuk, Daniel J Cantillon, Polychronis Dilaveris, Sergio J Dubner, Nabil El-Sherif, Jaroslaw Krol, Malgorzata Kurpesa, Maria Teresa La Rovere, Suave S Lobodzinski, Emanuela T Locati, Suneet Mittal, Brian Olshansky, Ewa Piotrowicz, Leslie Saxon, Peter H Stone, Larisa Tereshchenko, Gioia Turitto, Neil J Wimmer, Richard L Verrier, Wojciech Zareba, Ryszard Piotrowicz
Ambulatory ECG (AECG) is very commonly employed in a variety of clinical contexts to detect cardiac arrhythmias and/or arrhythmia patterns which are not readily obtained from the standard ECG. Accurate and timely characterization of arrhythmias is crucial to direct therapies that can have an important impact on diagnosis, prognosis or patient symptom status. The rhythm information derived from the large variety of AECG recording systems can often lead to appropriate and patient-specific medical and interventional management...
May 4, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28495063/topical-amiodarone-during-cardiac-surgery-does-epicardial-application-of-amiodarone-prevent-postoperative-atrial-fibrillation
#14
David Greenstein, Jordan Beau, Gary Gottlieb, Daniel Teller, Alexander Kulik
OBJECTIVES: Atrial fibrillation (AF) is a common complication after cardiac surgery. Topical amiodarone on the epicardium may help prevent postoperative AF while avoiding the side effects of its systemic administration. The purpose of this study was to evaluate the all-comer strategy of epicardial amiodarone application for the prevention of postoperative AF. METHODS: A retrospective observational study was performed that evaluated the incidence of new-onset AF in a consecutive series of cardiac surgery patients who were treated with either no amiodarone (historical control, n = 100), epicardial application of amiodarone mixed in a topical hydrogel (n = 50), or epicardial application of an amiodarone-soaked sealant patch (n = 50)...
April 13, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28490242/-telemetry-data-based-on-comparative-study-of-physical-activity-in-patients-with-resynchronization-device
#15
Csaba Melczer, László Melczer, Ilona Goják, Attila Kónyi, Sándor Szabados, L Bence Raposa, András Oláh, Pongrác Ács
INTRODUCTION: The effect of regular physical activity on health is widely recognized, but several studies have shown its key importance for heart patients. AIM: The present study aimed to define the PA % values, and to convert them into metabolic equivalent values (MET), which describes oxygen consumption during physical activity. METHOD: A total of seventeen patients with heart disease; 3 females and 14 males; age: 57.35 yrs ± 9.54; body mass 98...
May 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28489550/a-fully-integrated-wireless-soc-for-motor-function-recovery-after-spinal-cord-injury
#16
Yi-Kai Lo, Yen-Cheng Kuan, Stanislav Culaclii, Brian Kim, Po-Min Wang, Chih-Wei Chang, Jonathan A Massachi, Minji Zhu, Kuanfu Chen, Parag Gad, V Reggie Edgerton, Wentai Liu
This paper presents a wirelessly powered, fully integrated system-on-a-chip (SoC) supporting 160-channel stimulation, 16-channel recording, and 48-channel bio-impedance characterization to enable partial motor function recovery through epidural spinal cord electrical stimulation. A wireless transceiver is designed to support quasi full-duplex data telemetry at a data rate of 2 Mb/s. Furthermore, a unique in situ bio-impedance characterization scheme based on time-domain analysis is implemented to derive the Randles cell electrode model of the electrode-electrolyte interface...
May 5, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28488214/if-and-when-intrinsic-differences-and-environmental-stressors-influence-migration-in-brown-trout-salmo-trutta
#17
Kathryn S Peiman, Kim Birnie-Gauvin, Jonathan D Midwood, Martin H Larsen, Alexander D M Wilson, Kim Aarestrup, Steven J Cooke
Partial migration is a common phenomenon, yet the causes of individual differences in migratory propensity are not well understood. We examined factors that potentially influence timing of migration and migratory propensity in a wild population of juvenile brown trout (Salmo trutta) by combining experimental manipulations with passive integrated transponder telemetry. Individuals were subjected to one of six manipulations: three designed to mimic natural stressors (temperature increase, food deprivation, and chase by a simulated predator), an injection of exogenous cortisol designed to mimic an extreme physiological challenge, a sham injection, and a control group...
May 9, 2017: Oecologia
https://www.readbyqxmd.com/read/28480691/profile-of-match-performance-and-heart-rate-response-in-japanese-amputee-soccer
#18
Hirofumi Maehana, Aya Miyamoto, Kenichi Koshiyama, Toshio Tanaka Yanagiya, Masafumi Yoshimura
BACKGROUND: The purpose of this study was to profile the match performance and heart rate response in Japanese amputee soccer. METHODS: Twelve amputee soccer players participated in this study. Match data were collected 20 samples in 4 matches. Match performances data such as total distance, high-intensity running (HIR: ≥13km·h-1) were collected using a global positioning systems technology. Heart rate (HR) was recorded using short-range radio telemetry. In addition, the rating of perceived exertion (RPE) was assessed immediately using Borg's original after the first half and the second half...
May 5, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28480632/2017-ishne-hrs-expert-consensus-statement-on-ambulatory-ecg-and-external-cardiac-monitoring-telemetry
#19
Jonathan S Steinberg, Niraj Varma, Iwona Cygankiewicz, Peter Aziz, Paweł Balsam, Adrian Baranchuk, Daniel J Cantillon, Polychronis Dilaveris, Sergio J Dubner, Nabil El-Sherif, Jaroslaw Krol, Malgorzata Kurpesa, Maria Teresa La Rovere, Suave S Lobodzinski, Emanuela T Locati, Suneet Mittal, Brian Olshansky, Ewa Piotrowicz, Leslie Saxon, Peter H Stone, Larisa Tereshchenko, Gioia Turitto, Neil J Wimmer, Richard L Verrier, Wojciech Zareba, Ryszard Piotrowicz
Ambulatory ECG (AECG) is very commonly employed in a variety of clinical contexts to detect cardiac arrhythmias and/or arrhythmia patterns which are not readily obtained from the standard ECG. Accurate and timely characterization of arrhythmias is crucial to direct therapies that can have an important impact on diagnosis, prognosis or patient symptom status. The rhythm information derived from the large variety of AECG recording systems can often lead to appropriate and patient-specific medical and interventional management...
May 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/28474988/premedication-with-fentanyl-midazolam-improves-sevoflurane-anesthesia-for-surgical-intervention-in-laboratory-mice
#20
Miriam Lipiski, Margarete Arras, Paulin Jirkof, Nikola Cesarovic
Balanced anesthesia allows for a reduced dosage of each component, while inducing general anesthesia of sufficient depth with potentially fewer side effects. Here, we compare two anesthetic protocols combining sevoflurane anesthesia with pre-medication (ketamine [K] or fentanyl-midazolam [FM]) to a sevoflurane monoanesthesia (S) concerning their ability to provide reliable anesthesia suitable for moderate surgery in laboratory mice. Twenty-one female C57BL/6J mice assigned randomly to one of three protocols underwent a 50-min anesthesia and a sham embryo transfer...
January 1, 2017: Experimental Biology and Medicine
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