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https://www.readbyqxmd.com/read/29326112/epidemiology-of-new-onset-atrial-fibrillation-following-coronary-artery-bypass-graft-surgery
#1
Giovanni Filardo, Ralph J Damiano, Gorav Ailawadi, Vinod H Thourani, Benjamin D Pollock, Danielle M Sass, Teresa K Phan, Hoa Nguyen, Briget da Graca
OBJECTIVES: Postoperative atrial fibrillation (AF) following coronary artery bypass graft surgery (CABG) is significantly associated with reduced survival, but poor characterisation and inconsistent definitions present barriers to developing effective prophylaxis and management. We sought to address this knowledge gap. METHODS: From 2002 to 2010, 11 239 consecutive patients without AF underwent isolated CABG at five sites. Clinical data collected for the Society of Thoracic Surgeons (STS) Database were augmented with details on AF detected via continuous in-hospital ECG/telemetry monitoring to assess new-onset post-CABG AF (adjusted for STS risk of mortality); time to first AF; durations of first and longest AF episodes; total in-hospital time in AF; number of in-hospital AF episodes; operative mortality; stroke; discharge in AF; and length of stay (LOS)...
January 11, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29323578/effects-of-black-cohosh-and-estrogen-on-core-body-and-tail-skin-temperatures-in-ovariectomized-rats-by-telemetric-monitoring-with-dual-thermistor-probes
#2
Y Sun, L H Qin, X Chen, X Yan, L Mao, W Bai, J Kang
OBJECTIVES: To investigate the effects of black cohosh and estrogen on the temperature in ovariectomized rats, the core body temperature (CBT) and tail-skin temperature (TST) were simultaneously monitored and the relationship between these two temperatures was explored. METHODS: Twenty-four female Sprague-Dawley rats aged 8 weeks were randomly divided into four groups: sham-operated (SHAM), ovariectomized (OVX), OVX treated with estradiol valerate (OVX + E), and OVX treated with isopropanolic black cohosh extract (OVX + ICR)...
January 11, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/29319621/selective-cd28-inhibition-modulates-alloimmunity-and-cardiac-allograft-vasculopathy-in-anti-cd154-treated-monkeys
#3
Tianshu Zhang, Agnes M Azimzadeh, Wenji Sun, Natalie A O'Neill, Evelyn Sievert, Emily Bergbower, Gheorghe Braileanu, Lars Burdorf, Xiangfei Cheng, Thomas Monahan, Siamak Dahi, Donald Harris, Elana Rybak, Emily Welty, Anthony Kronfli, Chris Avon, Richard N Pierson
BACKGROUND: Selective CD28 inhibition is actively pursued as an alternative to B7 blockade using CTLA4-Ig based on the hypothesis that the checkpoint immune regulators CTLA-4 and PD-L1 will induce tolerogenic immune signals. We previously showed that blocking CD28 using a monovalent nonactivating reagent (single chain anti-CD28 Fv fragment linked to alpha-1 anti-trypsin: sc28AT) synergizes with calcineurin inhibitors in nonhuman primate (NHP) kidney and heart transplantation. Here, we explored the efficacy of combining a 3-week 'induction" sc28AT treatment with prolonged CD154 blockade...
January 10, 2018: Transplantation
https://www.readbyqxmd.com/read/29314105/ambulatory-diagnostic-ecg-monitoring-for-syncope-and-collapse-an-assessment-of-clinical-practice-in-the-united-states
#4
David G Benditt, Wayne O Adkisson, Richard Sutton, Robin K Mears, Scott Sakaguchi
INTRODUCTION: Diagnostic ambulatory ECG (AECG) monitoring is widely used for evaluating syncope and collapse, and practice guidelines provide recommendations regarding optimal AECG device selection. However, whether physicians utilize AECGs in accordance with the pertinent guidelines is unclear. This study assessed utilization of AECG monitoring systems for syncope and collapse diagnosis by physicians in the United States. METHODS AND RESULTS: A quantitative survey was undertaken of physicians comprising multiple specialties (Emergency Room, n = 35; Primary care, n = 35; Hospitalists, n = 30; Neurologists, n = 30; non-implanting, n = 34 and implanting-Cardiologists, n = 35)...
January 4, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29298233/empowering-bedside-nurses-to-lead-discussion-groups
#5
Kelli M Anspach, Laura Bruce, Shannon Rutberg
This article focuses on an approach three clinical nurse educators used to empower their Telemetry Education Nurse Team to grow professionally. The clinical nurse educators mentored the Telemetry Education Nurse Team, who were then able to facilitate successful discussion groups for their organization.
January 2018: Journal for Nurses in Professional Development
https://www.readbyqxmd.com/read/29296050/the-hospice-information-system-and-its-association-with-the-congruence-between-the-preferred-and-actual-place-of-death
#6
Huang-Ren Lin, Jen-Hung Wang, Jyh-Gang Hsieh, Ying-Wei Wang, Sheng-Lun Kao
Objective: A Hospice Information System (HIS) developed in eastern Taiwan in 2012 aimed to improve the quality of hospice care through an integrated system that provided telemetry-based vital sign records, online 24/7 consultations, online video interviews, and online health educations. The purpose of this study was to explore the congruence between the preferred and actual place of death (POD) among patients who received HIS services. Materials and Methods: A retrospective study was performed from January 2012 to August 2016...
October 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/29289782/applying-acoustic-telemetry-to-understand-contaminant-exposure-and-bioaccumulation-patterns-in-mobile-fishes
#7
Matthew D Taylor, Dylan E van der Meulen, Stephanie Brodie, Gwenaël Cadiou, Nathan A Knott
Contamination in urbanised estuaries presents a risk to human health, and to the viability of populations of exploited species. Assessing animal movements in relation to contaminated areas may help to explain patterns in bioaccumulation, and assist in the effective management of health risks associated with consumption of exploited species. Using polychlorinated dibenzodioxin and polychlorinated dibenzofuran (PCDD/Fs) contamination in Sydney Harbour estuary as a case study, we present a study that links movement patterns resolved using acoustic telemetry to the accumulation of contaminants in mobile fish on a multi-species basis...
December 28, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29287870/postoperative-bradycardia-following-adenotonsillectomy-in-children-does-intraoperative-administration-of-dexmedetomidine-play-a-role
#8
Benjamin Bush, Joseph D Tobias, Chen Lin, James Ruda, Kris R Jatana, Garth Essig, Jennifer Cooper, Dmitry Tumin, Charles A Elmaraghy
INTRODUCTION: Dexmedetomidine is a novel pharmacologic agent that has become a frequently used adjunct during care of pediatric patients with obstructive sleep apnea (OSA) undergoing tonsillectomy. While generally safe and effective, dexmedetomidine is associated with adverse effects of hypotension and bradycardia from its central sympatholytic effects. Due to safety concerns, our institution routinely admits patients with OSA for overnight cardiorespiratory monitoring following tonsillectomy...
January 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29280975/design-and-practical-evaluation-of-a-family-of-lightweight-protocols-for-heterogeneous-sensing-through-ble-beacons-in-iot-telemetry-applications
#9
Dixys L Hernández-Rojas, Tiago M Fernández-Caramés, Paula Fraga-Lamas, Carlos J Escudero
The Internet of Things (IoT) involves a wide variety of heterogeneous technologies and resource-constrained devices that interact with each other. Due to such constraints, IoT devices usually require lightweight protocols that optimize the use of resources and energy consumption. Among the different commercial IoT devices, Bluetooth and Bluetooth Low Energy (BLE)-based beacons, which broadcast periodically certain data packets to notify their presence, have experienced a remarkable growth, specially due to their application in indoor positioning systems...
December 27, 2017: Sensors
https://www.readbyqxmd.com/read/29276556/atrial-fibrillation-predictors-on-mobile-cardiac-telemetry-in-cryptogenic-ischemic-stroke
#10
Omar Kass-Hout, Tareq Kass-Hout, Ankit Parikh, Michael Hoskins, Stephen D Clements, Srikant Rangaraju, Ali Reza Noorian, Lauren Ayala, Debra Blanke, Laura Bamford, Aaron Anderson, Samir Belagaje, Manuel Yepes, Michael Frankel, Fadi Nahab
Background and Purpose: The objective of our study was to evaluate magnetic resonance imaging (MRI) and echocardiographic characteristics that would identify patients with cryptogenic ischemic stroke (IS) and transient ischemic attack (TIA) who subsequently developed paroxysmal atrial fibrillation (PAF) on mobile cardiac outpatient telemetry (MCOT). Methods: All patients with cryptogenic IS or TIA seen at the Emory University Hospital and Emory University Hospital Midtown from January 1, 2009, to June 30, 2013, who underwent MCOT were included in this analysis...
January 2018: Neurohospitalist
https://www.readbyqxmd.com/read/29260780/-the-results-of-bilateral-cochlear-implantation-in-the-children-who-survived-meningitis
#11
N A Daikhes, Kh M Diab, A R Siraeva, N V Tarasova, D S Kondratchikov, A S Machalov, O A Pashchinina, A O Kuznetsov, K D Yusifov
The objective of the present study was the prospective analysis of the results of bilateral cochlear implantation (CI) in the children presenting with bilateral ossification of the cochlea after they had survived meningitis. A total of 15 patients underwent the surgical intervention. In those exhibiting bilateral ossification of the basal cochlear helix over the 5 mm segment (up to first bend of the cochlear turn) and partial ossification of the second helix (in 6 children), the affected portions were removed with the placement of two choleostomies, the lower one (from the ossified membrane of the cochlear window) and the upper one (toward the second helix)...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/29250465/the-distribution-and-numbers-of-cheetah-acinonyx-jubatus-in-southern-africa
#12
Florian J Weise, Varsha Vijay, Andrew P Jacobson, Rebecca F Schoonover, Rosemary J Groom, Jane Horgan, Derek Keeping, Rebecca Klein, Kelly Marnewick, Glyn Maude, Jörg Melzheimer, Gus Mills, Vincent van der Merwe, Esther van der Meer, Rudie J van Vuuren, Bettina Wachter, Stuart L Pimm
Assessing the numbers and distribution of threatened species is a central challenge in conservation, often made difficult because the species of concern are rare and elusive. For some predators, this may be compounded by their being sparsely distributed over large areas. Such is the case with the cheetah Acinonyx jubatus. The IUCN Red List process solicits comments, is democratic, transparent, widely-used, and has recently assessed the species. Here, we present additional methods to that process and provide quantitative approaches that may afford greater detail and a benchmark against which to compare future assessments...
2017: PeerJ
https://www.readbyqxmd.com/read/29248268/trifluoroacetic-acid-three-times-the-fluoride-three-times-the-toxicity
#13
Christie Sun, Bryan Corbett
Trifluoroacetic acid (TFAA) is a carboxylic acid, similar to acetic acid, used industrially and in laboratories. There is a paucity of data regarding exposure and the concern is that toxicity may mimic that of hydrofluoric acid (HF), causing electrolyte abnormalities, dysrhythmia, and cardiac arrest. We report a case of a 27-year-old male that presents with a dermal exposure to TFAA. His exam was remarkable for a 4% body surface area partial thickness burn to the right forearm. There were no initial electrolyte abnormalities or dysrhythmias and the patient was admitted to telemetry monitoring overnight...
December 12, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29239867/effects-of-triple-combination-therapy-with-azilsartan-amlodipine-hydrochlorothiazide-on-office-home-blood-pressure-a-randomized-controlled-trial-in-japanese-essential-hypertensive-patients
#14
Hiromi Rakugi, Kohei Shimizu, Yuhei Sano, Yuya Nishiyama, Yoshinobu Kinugawa, Souhei Terashio
OBJECTIVE: The efficacy and safety of triple therapy with azilsartan (AZI), amlodipine besylate (AML), and hydrochlorothiazide (HCTZ) compared with dual therapy with AZI/AML or HCTZ monotherapy were evaluated in Japanese essential hypertensive patients in a double-blinded manner. PATIENTS AND METHODS: A total of 353 patients with office blood pressure (BP) of at least 150/95 mmHg were randomized to a 10-week treatment with AZI/AML/HCTZ 20/5/12.5 mg, AZI/AML/HCTZ 20/5/6...
December 12, 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/29237288/the-effect-of-continuous-glucose-monitoring-in-preventing-inpatient-hypoglycemia-in-general-wards-the-glucose-telemetry-system
#15
Elias K Spanakis, David L Levitt, Tariq Siddiqui, Lakshmi G Singh, Lillian Pinault, John Sorkin, Guillermo E Umpierrez, Jeffrey C Fink
BACKGROUND: Few studies have examined the use of continuous glucose monitoring (CGM) devices in the general wards. The aim of this pilot study was to examine whether CGM readings can be successfully transmitted from the bedside to a central monitoring device in the nursing station, and whether a glucose telemetry system can prevent hypoglycemic events. METHODS: We present pilot data on 5 consecutive insulin treated general medicine patients with type 2 diabetes (T2DM) whose glucose values were observed with CGM (DEXCOM) and the results were transmitted to a central nursing station monitoring system using DEXCOM Follow and Share 2 software...
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29229685/the-essential-role-of-phospho-t38-cpi-17-in-the-maintenance-of-physiological-blood-pressure-using-genetically-modified-mice
#16
Qunhui Yang, Wataru Fujii, Noriyuki Kaji, Shigeru Kakuta, Kodai Kada, Masayoshi Kuwahara, Hirokazu Tsubone, Hiroshi Ozaki, Masatoshi Hori
PKC-potentiated phosphorylation-dependent inhibitory protein of protein phosphatase 1 (CPI-17), an endogenous myosin phosphatase inhibitory protein, is considered a key molecule for Ca2+ sensitization of the contractile apparatus. Here, we have used clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 to generate CPI-17-deficient [knockout (KO)] and threonine 38 (T38)-phospho-resistant mice [Threonine mutant into Alanine (TA)], and then effects of CPI-17 on vascular contractility in vitro and mean blood pressure (MBP) in vivo were investigated...
December 11, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29228251/the-magnitude-and-time-course-of-iop-change-in-response-to-body-position-change-in-nonhuman-primates-measured-using-continuous-iop-telemetry
#17
Daniel C Turner, Brian C Samuels, Carrie Huisingh, Christopher A Girkin, J Crawford Downs
Purpose: To study the effect and time course of body position changes on IOP in nonhuman primates. Methods: We recorded continuous bilateral IOP measurements with a wireless telemetry implant in three rhesus macaques in seven different body positions. IOP measurements were acquired in the seated-upright, standing, prone, supine, right and left lateral decubitus positions (LDPs), and head-down inverted positions. Continuous IOP was recorded for 90 seconds in each position before returning to a supine reference position until IOP stabilized; measurements were averaged after IOP stabilized at each position...
December 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29225010/initiation-and-outcomes-with-class-ic-antiarrhythmic-drug-therapy
#18
Xu Gao, Avirup Guha, Benjamin Buck, Dilesh Patel, Melissa J Snider, Michael Boyd, Muhammad Afzal, Auroa Badin, Hemant Godara, Zhenguo Liu, Jaret Tyler, Raul Weiss, Steven Kalbfleisch, John Hummel, Ralph Augostini, Mahmoud Houmsse, Emile G Daoud
BACKGROUND: Expert opinion recommends performing exercise testing with initiation of Class Ic antiarrhythmic medication. OBJECTIVE: To evaluate the rate and reason for discontinuation of Ic agent within the first year of follow up, with particular attention to rate of proarrhythmia and the value of routine treadmill testing. METHODS: This is a single center retrospective cohort study including consecutive patients with atrial arrhythmias who were initiated on a Class Ic agent from 2011 to 2016...
December 7, 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29215757/hypothalamic-paraventricular-nucleus-neuronal-nitric-oxide-synthase-activity-is-a-major-determinant-of-renal-sympathetic-discharge-in-conscious-wistar-rats
#19
F D McBryde, B H Liu, E V Roloff, S Kasparov, J F R Paton
The paraventricular nucleus of the hypothalamus (PVN) plays a crucial role in cardiovascular and neuroendocrine regulation. Application of nitric oxide donors to the PVN stimulates GABAergic transmission, and may suppress sympathetic nerve activity (SNA) to lower arterial pressure. However, the role of endogenous nitric oxide within PVN in regulating renal SNA chronically remains to be established in conscious animals. To address this, we used our previously established lentiviral vectors to selectively knock down neuronal nitric oxide synthase (nNOS) in the PVN of conscious Wistar rats...
December 7, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/29212722/first-satellite-tracks-of-south-atlantic-sea-turtle-lost-years-seasonal-variation-in-trans-equatorial-movement
#20
Katherine L Mansfield, Milagros L Mendilaharsu, Nathan F Putman, Maria A G Dei Marcovaldi, Alexander E Sacco, Gustave Lopez, Thais Pires, Yonat Swimmer
In the South Atlantic Ocean, few data exist regarding the dispersal of young oceanic sea turtles. We characterized the movements of laboratory-reared yearling loggerhead turtles from Brazilian rookeries using novel telemetry techniques, testing for differences in dispersal during different periods of the sea turtle hatching season that correspond to seasonal changes in ocean currents. Oceanographic drifters deployed alongside satellite-tagged turtles allowed us to explore the mechanisms of dispersal (passive drift or active swimming)...
December 6, 2017: Proceedings. Biological Sciences
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