keyword
https://read.qxmd.com/read/38638081/burden-of-obstructive-sleep-apnea-in-patients-with-lung-cancer-and-its-effect-on-performance-status
#1
JOURNAL ARTICLE
Mohamed H Zidan, Hany M Shaarawy, Heba S Gharraf, Suzan F Helal, Maged Hassan, Rana Rizk
The association between lung cancer and obstructive sleep apnea has remained a matter of debate for years. Obstructive sleep apnea is thought to increase the incidence of lung cancer due to intermittent hypoxaemia and sleep fragmentation. The aim of this study is to assess the prevalence of obstructive sleep apnea in patients with lung cancer and its effect on those patients' performance status. This is a prevalence study that was conducted at Chest Diseases Department, Alexandria Main University Hospitals...
April 18, 2024: Journal of Sleep Research
https://read.qxmd.com/read/38631159/age-related-disparities-in-sleep-apnea-diagnosis-using-a-wearable-device-implications-of-4-vs-3-hypopnea-scoring-criteria
#2
JOURNAL ARTICLE
Farnaz AbbasiMoradi, Maria P Mogavero, Melissa Palomino, Raffaele Ferri, Lourdes M DelRosso
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) diagnosis relies on the Apnea-Hypopnea Index (AHI), with discrepancies arising from the 3% and 4% desaturation criteria. This study investigates age-related variations in OSA severity classification, utilizing data from 1201 adult patients undergoing Home Sleep Apnea Testing (HSAT) with SleepImage Ring@ . METHODS: The study employs Bland-Altman analysis to compare AHI values obtained with the 3% and 4% desaturation criteria...
April 1, 2024: Sleep Medicine
https://read.qxmd.com/read/38627338/the-core-syndrome-an-overlap-of-severe-asthma-obstructive-sleep-apnea-rhinosinusitis-and-esophageal-reflux
#3
JOURNAL ARTICLE
Pasquale Tondo, Anela Hoxhallari, Donato Lacedonia, Pietro Magaletti, Roberto Sabato, Maria Pia Foschino Barbaro, Giulia Scioscia
PURPOSE: Asthma, obstructive sleep apnea (OSA), rhinosinusitis, and esophageal reflux are conditions that may overlap, forming a syndrome known as CORE. Whenever clinical remission of severe asthma (SA) is not achieved, it is essential to investigate the presence of comorbidities, in particular the presence of OSA that may lead to the diagnosis of CORE syndrome. METHODS: The study was conducted on naive patients with SA and concomitant rhinosinusitis and esophageal reflux, referred to our institute since 2018...
April 16, 2024: Sleep & Breathing
https://read.qxmd.com/read/38619154/complex-adhd-challenging-case-when-simple-becomes-complex-managing-clinician-bias-and-navigating-challenging-family-dynamics-in-a-6-year-old-girl-with-adhd-and-developmental-delays
#4
JOURNAL ARTICLE
Jennifer Cervantes, Jenna Wallace, Annie Kennelly Helms, Elizabeth A Diekroger, Jason Fogler
Layla is a 6.7-year-old girl diagnosed with attention-deficit/hyperactivity disorder (ADHD)-predominantly hyperactive/impulsive type-delayed adaptive skills, enuresis, unspecified malnutrition, and feeding difficulties. She presented to developmental-behavioral pediatrics (DBP) in January 2022 due to caregiver concerns for autism spectrum disorder (ASD).Layla lives in a polyamorous family with her biological mother and father, mother's partner whom Layla refers to as her uncle, and her 2 half-siblings. There is a maternal history of special education services, schizoaffective disorder, bipolar disorder, multiple sclerosis, Wolff-Parkinson-White syndrome, and ADHD...
March 2024: Journal of Developmental and Behavioral Pediatrics: JDBP
https://read.qxmd.com/read/38616458/assessment-of-obstructive-sleep-apnoea-in-children-what-are-the-challenges-we-face
#5
REVIEW
Dominic A Fitzgerald, Joanna MacLean, Brigitte Fauroux
There is an increasing demand for the assessment of sleep-disordered breathing in children of all ages to prevent the deleterious neurocognitive and behaviour consequences of the under-diagnosis and under-treatment of obstructive sleep apnoea [OSA]. OSA can be considered in three broad categories based on predominating contributory features: OSA type 1 [enlarged tonsils and adenoids], type II [Obesity] and type III [craniofacial abnormalities, syndromal, storage diseases and neuromuscular conditions]. The reality is that sleep questionnaires or calculations of body mass index in isolation are poorly predictive of OSA in individuals...
April 4, 2024: Paediatric Respiratory Reviews
https://read.qxmd.com/read/38613859/objectively-assessed-sleep-quality-parameters-in-multiple-sclerosis-at-home-association-to-disease-disease-severity-and-physical-activity
#6
JOURNAL ARTICLE
Vaishali Vinod, Karolina Saegner, Walter Maetzler, Elke Warmerdam, Robbin Romijnders, Thorben Beyer, Robert Göder, Clint Hansen, Klarissa Stürner
BACKGROUND: Multiple Sclerosis (MS) is a chronic inflammatory autoimmune, neurodegenerative disease that affects regular mobility and leads predominantly to physical disability. Poor sleep quality, commonly reported in MS patients, impacts their physical activity (PA). Accelerometers monitor 24-h activity patterns, offering insights into disease progression in daily life. OBJECTIVE: To test if the sleep quality variables of MS patients, as assessed with wrist-worn accelerometers, differ from those of controls and are associated with PA and disease severity variables...
March 22, 2024: Sleep Medicine
https://read.qxmd.com/read/38610649/esophagus-dilation-and-quality-of-life-in-adults-with-scleroderma-and-concomitant-obstructive-sleep-apnea
#7
JOURNAL ARTICLE
Tugce Yakut, Caner Cinar, Sait Karakurt, Haner Direskeneli, Yasemin Yalcinkaya, Yüksel Peker
(1) Background : Systemic sclerosis (SSc) is a rare systemic disease, which often affects the esophagus, leading to dilation and complications such as dysphagia and reflux. Obstructive sleep apnea (OSA) is a chronic condition with recurrent episodes of upper airway collapsibility and is known to impair quality of life (QoL). The primary aim of this study was to investigate the occurrence of esophagus dilation in patients with SSc and concomitant OSA and, further, to address the impact of these conditions on QoL...
March 25, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610432/performance-evaluation-of-a-new-sport-watch-in-sleep-tracking-a-comparison-against-overnight-polysomnography-in-young-adults
#8
JOURNAL ARTICLE
Andrée-Anne Parent, Veronica Guadagni, Jean M Rawling, Marc J Poulin
Introduction : This study aimed to validate the ability of a prototype sport watch (Polar Electro Oy, FI) to recognize wake and sleep states in two trials with and without an interval training session (IT) 6 h prior to bedtime. Methods : Thirty-six participants completed this study. Participants performed a maximal aerobic test and three polysomnography (PSG) assessments. The first night served as a device familiarization night and to screen for sleep apnea. The second and third in-home PSG assessments were counterbalanced with/without IT...
March 30, 2024: Sensors
https://read.qxmd.com/read/38587464/daily-associations-between-salivary-cortisol-and-eeg-assessed-sleep-a-15-day-intensive-longitudinal-study
#9
JOURNAL ARTICLE
Yang Yap, Natasha Yan Chi Tung, Lin Shen, Bei Bei, Andrew Phillips, Joshua F Wiley
STUDY OBJECTIVES: Current evidence suggests that cortisol levels are bi-directionally associated with sleep. However, the daily, naturalistic cortisol-sleep associations remain unclear, as current evidence is mostly cross-sectional. This study tested whether pre-sleep cortisol predicts sleep duration and quality, and whether these sleep parameters predict the following day's diurnal cortisol slope using a 15-day intensive longitudinal design with electroencephalographic measures and saliva sampling...
April 8, 2024: Sleep
https://read.qxmd.com/read/38584515/sleep-duration-and-association-with-cardiometabolic-health-in-adolescents-and-adults-with-type-1-diabetes-results-from-the-bcqr-t1d-study
#10
JOURNAL ARTICLE
Stacey L Simon, Janet K Snell-Bergeon, Michal Schäfer, Alex J Barker, Lorna P Browne, Uyen Truong, Shoshana S Tell, Timothy Vigers, Amy D Baumgartner, Ellen Lyon, Sarit Polsky, Irene E Schauer, Kristen J Nadeau
AIM: Type 1 diabetes (T1D) increases the risk of morbidity and mortality from cardiovascular disease, and insufficient sleep is prevalent. Emerging evidence suggests a link between sleep and cardiometabolic health, but this has not been examined across the lifespan in individuals with T1D. We aimed to examine associations between sleep and cardiometabolic health in adolescents and adults with T1D in a secondary analysis of data from a 4-week double-blind, random-order, placebo-controlled crossover trial of bromocriptine quick release (BCQR) therapy with a 4-week washout in between conditions...
April 8, 2024: Diabetes, Obesity & Metabolism
https://read.qxmd.com/read/38582728/prevalence-of-and-factors-associated-with-burnout-in-pediatric-urology-fellows
#11
JOURNAL ARTICLE
Emily A Reeson, Daniel Salevitz, Bernice Alcanzo, Chung Yon Lin, Gwen M Grimsby
INTRODUCTION: The 2016 AUA census found 39% of practicing urologists experienced burnout. Burnout is a syndrome of emotional exhaustion, depersonalization, and decreased feelings of personal accomplishment due to workplace stress. Despite the demands of training, little is known about the prevalence of burnout in pediatric urology fellows. OBJECTIVE: To determine the prevalence of burnout in pediatric urology fellows and factors associated with higher levels of burnout...
March 18, 2024: Journal of Pediatric Urology
https://read.qxmd.com/read/38575160/adverse-pregnancy-outcomes-and-pharyngeal-flow-limitation-during-sleep-nulliparous-pregnancy-outcomes-study-monitoring-mothers-to-be-numom2b
#12
JOURNAL ARTICLE
Raichel M Alex, Dwayne L Mann, Ali Azarbarzin, Daniel Vena, Laura K Gell, Andrew Wellman, William A Grobman, Francesca L Facco, Robert M Silver, Grace W Pien, Judette M Louis, Phyllis C Zee, Michael Rueschman, Tamar Sofer, Susan Redline, Scott A Sands
RATIONALE: Pharyngeal flow limitation during pregnancy may be a risk factor for adverse pregnancy outcomes but was previously challenging to quantify. OBJECTIVE: To determine whether a novel objective measure of flow limitation identifies an increased risk of preeclampsia (primary outcome) and other adverse outcomes in a prospective cohort: Nulliparous Pregnancy Outcomes Study Monitoring Mothers-to-be. METHODS: Flow limitation severity scores (0%=fully obstructed, 100%=open airway)- quantified from breath-by-breath airflow shape-were obtained from home sleep tests during early (6-15 weeks) and mid (22-31 weeks) pregnancy...
April 4, 2024: European Respiratory Journal
https://read.qxmd.com/read/38566023/can-a-prolonged-healing-pressure-injury-be-benefited-by-using-an-ai-mattress-a-case-study
#13
JOURNAL ARTICLE
Tung Fang Ni, Jyh-Liang Wang, Chih-Kuang Chen, De Fen Shih, Jeng Wang
BACKGROUND: Pressure injuries are a common and serious issue for bedridden residents in long-term-care facilities. Areas of bony prominences, such as the scapula, sacrum, and heels, are more likely to develop pressure injuries. The management of pressure injury wounds include dressing changes, repositioning, away from moisture, decreasing the occurrence of friction and shear, and more. Some supportive surfaces are also used for pressure injury cases such as gel pads, alternating pressure air mattresses, and air-fluidized beds...
April 2, 2024: BMC Geriatrics
https://read.qxmd.com/read/38557875/common-mental-health-problems-and-associated-factors-among-recovered-covid-19-patients-in-rural-area-a-community-based-survey-in-bangladesh
#14
JOURNAL ARTICLE
Zobayer Ibne Zaid, Anika Tasnim, Md Maruf Haque Khan, Zubair Ahmed Ratan, Mohammad Tanvir Islam, M Atiqul Haque
PURPOSE: Since the coronavirus (COVID-19) was announced as being a global pandemic on 11 March, governments from all parts of the world declared a quarantine period, during which people were prohibited from leaving their homes (except for essential activities) to contain the spread of the virus. Since then, the population has faced different levels of restrictions (i.e., mobility, social activities) that limited participation in normal daily routines. Consequently, these restrictions may have adversely changed physical activity, diet, sleep patterns, and screen time or work routine...
2024: PloS One
https://read.qxmd.com/read/38548567/which-adolescents-are-more-likely-to-complete-home-based-sleep-manipulation-trials
#15
JOURNAL ARTICLE
Andrea L Fidler, Gargi Rajput, Nanhua Zhang, Dean W Beebe
OBJECTIVES: Attrition and nonadherence are common concerns that can distort findings in clinical trials. This study examines the potential for systematic attrition in the largest sample to date of adolescents undergoing sleep manipulation. METHODS: Using pooled data across two trials involving 242 adolescents, a cumulative logistic regression tested whether demographics and baseline sleep predicted study completion/adherence. RESULTS: Race, a composite measure of socioeconomic status, and its elements (e...
March 27, 2024: Sleep Health
https://read.qxmd.com/read/38547961/tirzepatide-for-the-treatment-of-obstructive-sleep-apnea-rationale-design-and-sample-baseline-characteristics-of-the-surmount-osa-phase-3-trial
#16
JOURNAL ARTICLE
Atul Malhotra, Josef Bednarik, Sujatro Chakladar, Julia P Dunn, Terri Weaver, Ron Grunstein, Ingo Fietze, Susan Redline, Ali Azarbarzin, Scott A Sands, Richard J Schwab, Mathijs C Bunck
BACKGROUND: Weight reduction is a standard recommendation for obstructive sleep apnea (OSA) treatment in people with obesity or overweight; however, weight loss can be challenging to achieve and maintain without bariatric surgery. Currently, no approved anti-obesity medication has demonstrated effectiveness in OSA management. This study is evaluating the efficacy and safety of tirzepatide for treatment of moderate to severe OSA in people with obesity. METHODS: SURMOUNT-OSA, a randomized, placebo -controlled, 52-week phase 3 trial, is investigating the efficacy and safety of tirzepatide for treatment of moderate to severe OSA (apnea hypopnea- index ≥15 events/h) in participants with obesity (body mass index ≥30 kg/m2 ) and an established OSA diagnosis...
March 26, 2024: Contemporary Clinical Trials
https://read.qxmd.com/read/38546939/sleep-duration-and-social-jetlag-in-healthy-adolescents-association-with-anxiety-depression-and-chronotype-a-pilot-study
#17
JOURNAL ARTICLE
Solveig Magnusdottir, Ingibjorg Magnusdottir, Audur Karen Gunnlaugsdottir, Hugi Hilmisson, Laufey Hrolfsdottir, Anna Eyfjord Eiriksdottir M Paed
PURPOSE: Misalignment between sleep opportunity and chronotype preference during adolescence may affect sleep and mental health. The aim of this study was to objectively evaluate sleep duration and social jetlag (SJL) to observe if there is a relationship with anxiety, depression, or chronotype. METHODS: Community based cohort study (n = 65) was conducted in Northern Europe. Participants recorded their sleep during the regular school schedule for 3 school nights and 2 free nights with FDA-cleared/EU Medical Device Directive (CE-02862) compliant home sleep test...
March 28, 2024: Sleep & Breathing
https://read.qxmd.com/read/38545244/effectiveness-of-mandibular-advancement-devices-in-positional-osa-patients-a-retrospective-analysis-of-predictive-variables-in-a-sample-of-adult-patients
#18
JOURNAL ARTICLE
Floriana Pintucci, Francesca Cremonini, Giulia Romagnolo, Gianluca Giorgio Marrano, Francesca Barbanti, Giorgio Alfredo Spedicato, Claudio Vicini, Luca Lombardo
Objectives  To evaluate the efficacy of mandibular advancement devices (MADs) in improving apnea-hypopnea index (AHI) in positional obstructive sleep apnea (POSA), compared with a control group of nonpositional OSA (NPOSA) patients, from mild to very severe degree, in order to to find the main variables characterizing the examined group as potential predictors of treatment success. Materials and Methods  In the present observational study, we retrospectively collected polysomnographic records of 39 positional adult patients, divided into 30 supine isolated OSA (siOSA) and 9 supine predominant OSA (spOSA) undergoing MADs from 2003 to 2019, and compared with those of a control group of 47 NPOSA patients...
March 2024: Sleep Science
https://read.qxmd.com/read/38534798/a-protocol-for-evaluating-digital-technology-for-monitoring-sleep-and-circadian-rhythms-in-older-people-and-people-living-with-dementia-in-the-community
#19
JOURNAL ARTICLE
Ciro Della Monica, Kiran K G Ravindran, Giuseppe Atzori, Damion J Lambert, Thalia Rodriguez, Sara Mahvash-Mohammadi, Ullrich Bartsch, Anne C Skeldon, Kevin Wells, Adam Hampshire, Ramin Nilforooshan, Hana Hassanin, The Uk Dementia Research Institute Care Research Amp Technology Research Group, Victoria L Revell, Derk-Jan Dijk
Sleep and circadian rhythm disturbance are predictors of poor physical and mental health, including dementia. Long-term digital technology-enabled monitoring of sleep and circadian rhythms in the community has great potential for early diagnosis, monitoring of disease progression, and assessing the effectiveness of interventions. Before novel digital technology-based monitoring can be implemented at scale, its performance and acceptability need to be evaluated and compared to gold-standard methodology in relevant populations...
February 29, 2024: Clocks & Sleep
https://read.qxmd.com/read/38524766/assessing-the-real-world-long-term-impact-of-lemborexant-on-sleep-quality-in-a-home-based-clinical-study
#20
Seiko Miyata, Kunihiro Iwamoto, Ippei Okada, Akihiro Fujimoto, Yuki Kogo, Daisuke Mori, Manabu Amano, Nao Matsuyama, Kazuki Nishida, Masahiko Ando, Toshiaki Taoka, Shinji Naganawa, Norio Ozaki
PURPOSE: Both subjective and objective evaluations are essential for the treatment of insomnia. Lemborexant has been shown to be effective in the long-term based solely on a subjective basis, and no long-term objective measures have been evaluated under natural sleep conditions. Small, lightweight sleep electroencephalogram (EEG) monitor was used, instead of polysomnography, to objectively evaluate sleep at home 4 and 12 weeks after lemborexant treatment. PATIENTS AND METHODS: Adults and elderly subjects with insomnia disorder, per the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, were enrolled in this open-label, single-arm, single-center trial...
2024: Nature and Science of Sleep
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