keyword
Keywords Non-ischemic Dilated Cardiomyo...

Non-ischemic Dilated Cardiomyopathy

https://read.qxmd.com/read/38028049/pseudo-dilated-cardiomyopathy-dilated-cardiomyopathy-like-changes-due-to-a-combination-of-stuck-mechanical-mitral-valve-and-coronary-microvascular-dysfunction-an-autopsy-case
#21
Sato Namura, Hiroki Matsuzoe, Mayumi Inaba, Ryo Nishio, Daisuke Matsumoto, Hiroshi Takaishi
Thrombus formation in the microvessels and endocardium was suggestive of endothelial cell damage, myocardial ischemia, and a decreased coronary flow reserve. Sustained pulmonary hypertension due to thrombosis worsened the biventricular dysfunction.
November 2023: Clinical Case Reports
https://read.qxmd.com/read/38016680/utilities-and-limitations-of-cardiac-magnetic-resonance-imaging-in-dilated-cardiomyopathy
#22
REVIEW
Min Jae Cha, Yoo Jin Hong, Chan Ho Park, Yoon Jin Cha, Tae Hoon Kim, Cherry Kim, Chul Hwan Park
Dilated cardiomyopathy (DCM) is one of the most common types of non-ischemic cardiomyopathy. DCM is characterized by left ventricle (LV) dilatation and systolic dysfunction without coronary artery disease or abnormal loading conditions. DCM is not a single disease entity and has a complex historical background of revisions and updates to its definition because of its diverse etiology and clinical manifestations. In cases of LV dilatation and dysfunction, conditions with phenotypic overlap should be excluded before establishing a DCM diagnosis...
December 2023: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://read.qxmd.com/read/37998524/differences-in-androgen-receptor-expression-in-human-heart-tissue-in-various-types-of-cardiomyopathy-and-in-aortic-valve-stenosis
#23
JOURNAL ARTICLE
Katja Eildermann, Sabrina Goldmann, Ulrich Krause, David Backhoff, Friedrich A Schöndube, Thomas Paul, Thomas Quentin, Matthias J Müller
Background : Sex-specific differences in heart disease outcomes are influenced by the levels of the steroid hormones, estrogen and testosterone. While the roles of estrogen receptors in cardiac disease are well-studied in animals and humans, respective research on androgen receptors (AR) is limited. Here we investigate AR protein and mRNA expression in human myocardium of various cardiac diseases. Methods : AR expression was analyzed by western blotting in myocardium from human non-failing hearts (NF, n = 6) and patients with aortic stenosis (AS, n = 6), hypertrophic cardiomyopathy (HCM, n = 7), dilated cardiomyopathy (DCM, n = 7), and ischemic cardiomyopathy (ICM, n = 7)...
November 17, 2023: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/37998514/optimal-cardiac-resynchronization-therapy-with-conduction-system-pacing-guided-by-electro-anatomical-mapping-a-case-report
#24
Catalin Pestrea, Roxana Enache, Ecaterina Cicala, Radu Vatasescu
INTRODUCTION: Biventricular pacing has been the gold standard for cardiac resynchronization therapy in patients with left bundle branch block and severely reduced left ventricular ejection fraction for decades. However, in the past few years, this role has been challenged by the promising results of conduction system pacing in these patients, which has proven non-inferior and, at times, superior to biventricular pacing regarding left ventricular function outcomes. One of the most important limitations of both procedures is the long fluoroscopy times...
November 9, 2023: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/37970859/the-relationship-between-global-left-ventricular-function-as-indicated-by-the-tei-index-and-long-term-survival-in-patients-with-non-ischemic-dilated-cardiomyopathy
#25
JOURNAL ARTICLE
M Karabacak, A Peynirci, O Ozdil, Senol Tayyar, M S Kuyumcu
AIM: Idiopathic dilated cardiomyopathy (DCM) is one of the leading causes of low ejection fraction (EF) heart failure (HF). The Tei index is a reliable marker that reflects both left ventricular (LV) systolic and diastolic function, and it has prognostic value in patients with DCM. We aimed to investigate the relationship between the Tei index and long-term survival in non-ischemic, DCM patients. MATERIAL AND METHODS: The present study included 98 patients with non-ischemic DCM...
November 8, 2023: Kardiologiia
https://read.qxmd.com/read/37893478/associations-between-oral-glucose-lowering-agents-and-increased-risk-for-life-threatening-arrhythmias-in-patients-with-type-2-diabetes-mellitus-a-literature-review
#26
REVIEW
Cristina Tudoran, Mariana Tudoran, Catalina Giurgi-Oncu, Ahmed Abu-Awwad, Simona-Alina Abu-Awwad, Florica Voiţă-Mekereş
Background and Objectives : The relationship between type 2 diabetes mellitus (T2DM) and cardiovascular (CV) morbidity and mortality is well-established. Ventricular arrhythmias (VA) are frequently diagnosed in patients with T2DM, especially in those with associated coronary syndrome, non-ischemic dilated cardiomyopathy (NIDCM), and heart failure (HF). In these patients, VA and sudden cardiac arrest (SCA) are considered responsible for more than 50% of CV deaths. Newly developed glucose-lowering agents (GLA) seem not only to ameliorate CV morbidity and mortality, but also to reduce the risk of VA and SCA...
October 2, 2023: Medicina
https://read.qxmd.com/read/37887857/potential-prognostic-relevance-of-left-ventricular-global-longitudinal-strain-and-of-the-summation-of-the-mitral-and-tricuspid-regurgitation-volume-in-patients-with-non-ischemic-dilated-cardiomyopathy
#27
JOURNAL ARTICLE
Karolina Mėlinytė-Ankudavičė, Eglė Ereminienė, Vaida Mizarienė, Gintarė Šakalytė, Jurgita Plisienė, Renaldas Jurkevičius
BACKGROUND: The aim of this pilot study was to determine the potential prognostic relevance of novel multidirectional myocardial and volumetric echocardiographic parameters in patients with non-ischemic dilated cardiomyopathy (NIDCM). METHODS: Multidirectional myocardial parameters (longitudinal, radial, and circumferential left-ventricular (LV) strain using speckle tracking echocardiography) and a new volumetric parameter (the sum of the mitral and tricuspid regurgitation volume (mitral-tricuspid regurgitation volume) were assessed...
September 27, 2023: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/37880753/safety-and-outcomes-analysis-transcatheter-implantation-of-autologous-angiogenic-cell-precursors-for-the-treatment-of-cardiomyopathy
#28
JOURNAL ARTICLE
Jane R Schubart, Amirhossein Zare, Roberto M Fernandez-de-Castro, Hector Rosario Figueroa, Ina Sarel, Kelly Tuchman, Kaitlyn Esposito, Fraser C Henderson, Ernst von Schwarz
BACKGROUND: Stem cell transplantation is an emerging therapy for severe cardiomyopathy, proffering stem cell recruitment, anti-apoptosis, and proangiogenic capabilities. Angiogenic cell precursors (ACP-01) are autologous, lineage-specific, cells derived from a multipotent progenitor cell population, with strong potential to effectively engraft, form blood vessels, and support tissue survival and regeneration. METHODS: This IRB approved outcome analysis reports upon 74 consecutive patients who failed medical management for severe cardiomyopathy, and were selected to undergo transcatheter intramyocardial or intracoronary implantation of ACP-01...
October 26, 2023: Stem Cell Research & Therapy
https://read.qxmd.com/read/37873442/deriving-explainable-metrics-of-left-ventricular-flow-by-reduced-order-modeling-and-classification
#29
María Guadalupe Borja, Pablo Martinez-Legazpi, Cathleen Nguyen, Oscar Flores, Andrew M Kahn, Javier Bermejo, Juan C Del Álamo
BACKGROUND: Extracting explainable flow metrics is a bottleneck to the clinical translation of advanced cardiac flow imaging modalities. We hypothesized that reduced-order models (ROMs) of intraventricular flow are a suitable strategy for deriving simple and interpretable clinical metrics suitable for further assessments. Combined with machine learning (ML) flow-based ROMs could provide new insight to help diagnose and risk-stratify patients. METHODS: We analyzed 2D color-Doppler echocardiograms of 81 non-ischemic dilated cardiomyopathy (DCM) patients, 51 hypertrophic cardiomyopathy (HCM) patients, and 77 normal volunteers (Control)...
October 5, 2023: medRxiv
https://read.qxmd.com/read/37840136/systematic-in-vivo-candidate-evaluation-uncovers-therapeutic-targets-for-lmna-dilated-cardiomyopathy-and-risk-of-lamin-a-toxicity
#30
JOURNAL ARTICLE
Chia Yee Tan, Pui Shi Chan, Hansen Tan, Sung Wei Tan, Chang Jie Mick Lee, Jiong-Wei Wang, Shu Ye, Hendrikje Werner, Ying Jie Loh, Yin Loon Lee, Matthew Ackers-Johnson, Roger S Y Foo, Jianming Jiang
BACKGROUND: Dilated cardiomyopathy (DCM) is a severe, non-ischemic heart disease which ultimately results in heart failure (HF). Decades of research on DCM have revealed diverse aetiologies. Among them, familial DCM is the major form of DCM, with pathogenic variants in LMNA being the second most common form of autosomal dominant DCM. LMNA DCM is a multifactorial and complex disease with no specific treatment thus far. Many studies have demonstrated that perturbing candidates related to various dysregulated pathways ameliorate LMNA DCM...
October 16, 2023: Journal of Translational Medicine
https://read.qxmd.com/read/37793054/left-bundle-branch-area-pacing-too-far-away-from-the-tricuspid-annulus-may-cause-pacing-induced-cardiomyopathy
#31
JOURNAL ARTICLE
Michael Meyers, Xiaoke Liu
BACKGROUND: Physiologic pacing through left bundle branch area pacing (LBBAP) has recently been shown to be a very promising alternative for cardiac resynchronization therapy (CRT) and to avoid pacing induced cardiomyopathy. However, it is not clear whether the position of LABBP lead may affect the clinical outcomes. CASE REPORT: We here report a case of likely LBBAP induced worsening heart failure and cardiomyopathy reversed by re-positioning of the pacing lead towards a more annular position...
October 4, 2023: Pacing and Clinical Electrophysiology: PACE
https://read.qxmd.com/read/37778991/evaluation-of-left-ventricular-mass-in-different-cardiac-geometry-using-three-dimensional-contrast-enhanced-echocardiography
#32
JOURNAL ARTICLE
Meiqing Zhang, Xu Chen, Feifei Yang, Yanjie Song, Dai Zhang, Qiang Chen, Yongjiang Ma, Shuhua Wang, Dongdong Ji, Zhongxiang Duan, Liwei Zhang, Qiushuang Wang
A total of 69 patients were enrolled in the study, including 23 patients with hypertrophic cardiomyopathy (HCM), 26 patients with Left Ventricle (LV) enlargement comprising 16 dilated cardiomyopathy (DCM) patients and 10 ischemic cardiomyopathy (ICM) patients, and 20 control subjects. All patients underwent 2DE, contrast-enhanced 2DE (Contrast-2DE), 3DE, Contrast-3DE, and single photon emission computed tomography (SPECT) examinations. The 2DE-AL and 3DE methods measured the left ventricular mass (LVM). The results were compared with those measured by SPECT...
2023: International Heart Journal
https://read.qxmd.com/read/37769574/obesity-paradox-in-heart-failure-revisited-etiology-as-effect-modifier
#33
JOURNAL ARTICLE
Liyan Huang, Xuemei Zhao, Lin Liang, Pengchao Tian, Yuyi Chen, Mei Zhai, Yan Huang, Qiong Zhou, Yuhui Zhang, Jian Zhang
The prognostic value of overweight/obesity in heart failure (HF) may vary according to HF etiologies. We aim to determine whether body mass index has differential impacts on survival among hospitalized HF patients with varying etiologies. Consecutive hospitalized HF patients between December 2006 and December 2017 were included. Multivariable analyses, including Cox proportional hazard models and restricted cubic splines, were used to investigate the impact of body mass index on mortality by HF etiology. Among the 3,836 patients included (mean age 57...
September 26, 2023: American Journal of Cardiology
https://read.qxmd.com/read/37753363/iatrogenic-orbital-hematoma-an-exceptional-complication-of-upper-gastrointestinal-endoscopy
#34
Myriam Ayari, Sameh Riahi, Imen Abdelaali, Taieb Jomni, Mohamed Hedi Douggui
Iatrogenic orbital hematoma is a rare event, most often manifested by a painful exophthalmos that could compromise the patient's visual prognosis. We report the case of a 51-year-old female patient with a history of non-ischemic dilated cardiomyopathy and high blood pressure, who developed a painful exophthalmos following an upper gastrointestinal sedation-free endoscopy. The diagnosis of an intra-orbital hematoma was made by computed tomographic scan and a conservative attitude was adopted after a thorough ophthalmological examination...
December 2023: Future Science OA
https://read.qxmd.com/read/37753057/prognostic-implication-of-liver-fibrosis-scores-in-patients-with-non-ischemic-dilated-cardiomyopathy
#35
JOURNAL ARTICLE
Yupeng Liu, Jingjing Song, Wenyao Wang, Yi-Da Tang
AIMS: Liver fibrosis was associated with adverse outcomes in various cardiovascular diseases. The current risk stratification of non-ischemic dilated cardiomyopathy (NIDCM) still largely depends on the left ventricular ejection fraction (LVEF). At present, the relationship between liver fibrosis and prognosis in patients with NIDCM remains blank. METHODS AND RESULTS: A total of 433 NIDCM patients were analysed in this study. Liver fibrosis was assessed by three liver fibrosis scores (LFS), including aspartate aminotransferase to platelet ratio index (APRI), aspartate aminotransferase/alanine aminotransferase ratio (AST/ALT ratio), and gamma-glutamyltransferase to platelet ratio (GPR)...
September 2023: Eur Heart J Open
https://read.qxmd.com/read/37745419/dcm-progress-predicting-end-stage-heart-failure-in-non-ischemic-dilated-cardiomyopathy-patients
#36
A F Schmidt, P Leinveber, R Panovsky, L Soukup, P Machac, R R van de Leur, A Sammani, K Lekadir, A Ter Riele, F W Asselbergs, M J Boonstra
AIMS: Patients with non-ischemic dilated cardiomyopathy (DCM) are at considerable risk for end-stage heart failure (HF), requiring close monitoring to identify early signs of disease. We aimed to develop a model to predict the 5-years risk of end-stage HF, allowing for tailored patient monitoring and management. METHODS AND RESULTS: Derivation data were available from a Dutch cohort of 293 DCM patients, with external validation available from a Czech Republic cohort of 235 DCM patients...
September 11, 2023: medRxiv
https://read.qxmd.com/read/37736356/transcatheter-aortic-valve-replacement-among-heart-transplant-recipients-with-donor-aortic-valve-diseases-a-systematic-review-of-the-literature
#37
JOURNAL ARTICLE
Saeed Shoar, Ashok Chaudhary, Varinder Bansro, Mohammad Sadegh Asadi
BACKGROUND: Despite high surgical risk among heart transplant (HTx) recipients, who develop aortic valve diseases (AVD), transcutaneous aortic valve replacement (TAVR) has been scarcely reported as a viable option in this patient population. METHODS: A systematic review was conducted to identify studies reporting the outcomes of HTx recipients who developed AVD of the donor heart and underwent TAVR. Studies were eligible if they provided individual-level data for HTx recipients, who underwent TAVR on the donor heart...
2023: American Journal of Cardiovascular Disease
https://read.qxmd.com/read/37721634/accurate-classification-of-non-ischemic-cardiomyopathy
#38
REVIEW
Yifan Wang, Hao Jia, Jiangping Song
PURPOSE OF REVIEW: This article aims to review the accurate classification of non-ischemic cardiomyopathy, including the methods, basis, subtype characteristics, and prognosis, especially the similarities and differences between different classifications. RECENT FINDINGS: Non-ischemic cardiomyopathy refers to a myocardial disease that excludes coronary artery disease or ischemic injury and has a variety of etiologies and high incidence. Recent studies suggest that traditional classification methods based on primary/mixed/acquired or genetic/non-genetic cannot meet the precise needs of contemporary clinical management...
October 2023: Current Cardiology Reports
https://read.qxmd.com/read/37676474/right-ventricular-systolic-function-and-mechanical-dyssynchrony-in-ischemic-or-non-ischemic-dilated-cardiomyopathy-a-speckle-tracking-study
#39
JOURNAL ARTICLE
Asmaa Ahmed Ali, Shaimaa Ahmed Habib, Ola Hassan AbdElaziz, Safaa Abouelfadl Mohammad
AIM: This study assessed RV dyssynchrony (irrespective to QRS duration) and RV systolic function in non-ischemic dilated cardiomyopathy (NIDCM) versus ischemic dilated cardiomyopathy (IDCM) patients by using different echo-Doppler modalities. METHODS: Eighty-five cases (48 patients with DCM [whether ischemic or non-ischemic] and 37 age-matched healthy controls) were studied. Conventional echo-Doppler study, tissue Doppler (TDI), and speckle tracking (STE) were carried out to measure LV and RV systolic function...
September 7, 2023: Echocardiography
https://read.qxmd.com/read/37659618/lmna-cardiomyopathy-important-considerations-for-the-heart-failure-clinician
#40
REVIEW
Karen Flores Rosario, Ravi Karra, Kaitlyn Amos, Andrew P Landstrom, Neal K Lakdawala, Kyla Brezitski, Han Kim, Adam D Devore
BACKGROUND: A diagnosis of Lamin proteins A and C cardiomyopathy (LMNA-CM) not only impacts disease prognosis, but also leads to specific guideline-recommended treatment options for these patients. This etiology is fundamentally different from other genetic causes of dilated CM. METHODS AND RESULTS: LMNA-CM often presents early in the third to fourth decades and there is an age-dependent penetrance of nearly 90% among those with a positive genotype for LMNA-CM. Oftentimes, electrical abnormalities with either conduction disturbances and/or either atrial or ventricular arrhythmias manifest before there is imaging evidence of left ventricular dysfunction...
December 2023: Journal of Cardiac Failure
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