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regurgitant valvular lesions

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https://www.readbyqxmd.com/read/28780660/update-on-valvular-heart-disease-in-pregnancy
#1
REVIEW
Lucy M Safi, Sarah V Tsiaras
Valvular heart disease in women of childbearing age poses an increased risk of adverse maternal and fetal outcomes, and management in pregnancy can be challenging. Ideally, patients with suspected valvular disease should have preconception counseling by a multidisciplinary team including cardiologists with expertise in pregnancy and a maternal-fetal medicine specialist. Preconception planning should include a cardiac assessment of maternal risk, determination of frequency of surveillance, and a cardiovascular management plan during delivery...
September 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28721493/modelling-of-lesions-associated-with-functional-mitral-regurgitation-in-an-ex-vivo-platform
#2
Michal Jaworek, Federico Lucherini, Claudia Romagnoni, Guido Gelpi, Monica Contino, Paolo Romitelli, Carlo Antona, Gianfranco B Fiore, Riccardo Vismara
Functional mitral regurgitation (FMR) is a complex pathology involving valvular and subvalvular structures reconfiguration, and its treatment is considered challenging. There is a lack of experimental models allowing for reliable preclinical FMR treatments' evaluation in a realistic setting. A novel approach to simulate FMR was developed and incorporated into an ex vivo passive beating heart platform. FMR was obtained by dilating the mitral annulus (MA) mainly in the antero-posterior direction and displacing the papillary muscles (PMs) apically and laterally by ad hoc designed and 3D printed dilation and displacing devices...
July 18, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28616570/a-study-of-spectrum-of-rheumatic-heart-disease-in-a-tertiary-care-hospital-in-central-nepal
#3
S Laudari, G Subramanyam
BACKGROUND AND AIMS: Rheumatic heart disease is one of the most common cause for heart failure and associated mortalities/morbidities in the young population in developing countries like Nepal imparting huge familial, social and manpower burden. MATERIALS AND METHODS: This is a hospital based descriptive cross-sectional study during June 2014 to April 2016 over a period of 22 months at College of Medical Sciences-Bharatpur including 235 patients with clinical and/or echocardiographic evidence of definite rheumatic heart disease...
June 2017: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28460759/utility-of-physical-examination-and-comparison-to-echocardiography-for-cardiac-diagnosis
#4
Ashish Patel, Nitin Singh Tomar, Anil Bharani
OBJECTIVE: To find out the accuracy of cardiac auscultation using non-digital stethoscope in physical diagnosis of cardiac diseases. METHODS: We enrolled 104 consecutive patients with abnormal cardiac auscultatory findings attending cardiology clinic and not previously evaluated by echocardiography. One time detailed cardiac physical examination followed by echocardiography within 1 month was undertaken. Agreement between two methods was calculated using mean pair percentage agreement, kappa statistics (κ) and calculation of 95% confidence interval (CI) for kappa statistics...
March 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28295517/a-giant-aneurysm-of-noncoronary-sinus-of-valsalva-concomitant-with-aortic-regurgitation-and-mitral-regurgitation
#5
Yi Luo, Zhi Fang, Wei Meng
Aneurysms of the sinus of Valsalva (ASV) are rare, with an incidence ranging from 0.1% to 3.5% of all congenital cardiac defects and a prevalence of 0.009% in an autopsy series.ASVs occur much more frequently in the right coronary sinus of Valsalva. Previous reports, based on necropsy and cardiac surgery findings, estimated that 20% of ASVs are unruptured. Patients with an unruptured ASV may remain asymptomatic for a long period of time until rupture. They may also presented with dyspnea, palpitation, and angina-like chest pain...
March 14, 2017: Echocardiography
https://www.readbyqxmd.com/read/28291779/echocardiographic-diagnosis-of-rare-pathological-patterns-of-sinus-of-valsalva-aneurysm
#6
Yali Yang, Li Zhang, Xinfang Wang, Qing Lü, Lin He, Jing Wang, Bin Wang, Ling Li, Li Yuan, Jinfeng Liu, Shuping Ge, Mingxing Xie
OBJECTIVE: To evaluate the value and improve the diagnostic accuracy of echocardiography in the diagnosis of a sinus of Valsalva aneurysm (SVA) with rare pathological patterns. METHODS: Echocardiographic features and surgical findings from 270 Chinese patients with SVA treated in the last 18 years (1995-2013) at the Union Hospital were compared retrospectively; 22 of 270 cases had rare patterns. RESULTS: The patients with SVA, a rare origin, a rare extending position, or a rare course accounted for 3...
2017: PloS One
https://www.readbyqxmd.com/read/28228300/lutembacher-s-syndrome-is-the-mitral-pathology-always-rheumatic
#7
Pradeep Vaideeswar, Supreet Marathe
The mitral valve disease (MVD) in Lutembacher's syndrome has been infrequently analyzed from a pathological standpoint. In this study, we have attempted to elucidate the pathology of MVD in this interesting syndrome in 44 autopsied cases of combined non-primum atrial septal defect (ASD) and MVD collected over 16 years. The patients were divided into 3 groups: Group 1: non-primum ASD with clinically diagnosed mitral stenosis (MS)±regurgitation, Group 2: non-primum ASD with clinically diagnosed mitral regurgitation (MR) and, Group 3: non-primum ASD with no clinically evident MVD, but with mitral valve pathology diagnosed at autopsy...
January 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28038799/the-role-of-myocardial-performance-index-in-assessment-of-left-ventricular-function-in-patients-with-valvular-mitral-regurgitation
#8
Muataz Fawzi Hussein, Samirra Rashid Jabbar Al-Mayahi, Samar I Essa
BACKGROUND: Mitral regurgitation (MR) is the most commonly encountered valve lesion in modern clinical practice. Severe mitral regurgitation may cause systolic dysfunction. Left ventricular ejection fraction may not be an accurate measurement of LV function in patients with mitral insufficiency. Myocardial performance index (MPI) is a simple non invasive measure of myocardial function. METHODS: The study involved 50 patients with valvular mitral regurgitation and 50 healthy subjects as a control group...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27866289/echocardiographic-findings-in-asymptomatic-systemic-lupus-erythematosus-patients
#9
Abdel GaffarA Mohammed, Abdulaziz A Alghamdi, Mohammad A ALjahlan, Ibrahim A Al-Homood
The aim of this study is to use transthoracic echocardiographic (TTE) imaging methods to identify cardiac dysfunction in asymptomatic systemic lupus erythematosus (SLE) patients and to determine the association between echocardiographic findings and serology. This is a prospective cross-sectional study where 50 patients with confirmed diagnoses of SLE were recruited from rheumatology outpatient clinics. Clinical and serological evaluation to confirm the diagnosis of lupus was done in all patients. Fifty SLE patients, 46 (92%) females and 4 (8%) males, were recruited...
March 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/27567391/characteristics-and-outcomes-of-indian-children-enrolled-in-a-rheumatic-heart-disease-registry
#10
Anurag Mehta, Anita Saxena, Rajnish Juneja, Sivasubramanian Ramakrishnan, Saurabh Gupta, Shyam Sundar Kothari
BACKGROUND: Rheumatic heart disease (RHD) causes significant morbidity among children of low and middle-income countries. We aimed to assess characteristics and outcomes of Indian children enrolled in a tertiary care hospital RHD registry. METHODS: Pediatric patients (≤18years) were prospectively enrolled over three years. We evaluated their clinical and echocardiographic characteristics, valvular interventions, adherence to penicillin prophylaxis, and mortality...
November 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27537190/transcatheter-mitral-valve-implantation-30-day-outcome-of-first-in-man-experience-with-an-apically-tethered-device
#11
Cesare Quarto, Simon Davies, Alison Duncan, Alistair Lindsay, Georg Lutter, Lucian Lozonschi, Neil Moat
OBJECTIVE: A small number of transcatheter mitral valve implants (TMVIs) have been reported using devices designed to treat secondary mitral regurgitation (MR). However, MR has many etiologies, and patients have a broad spectrum of annular size, geometry, and lesions. There are a number of technical challenges for TMVI including left ventricular outflow tract obstruction and paravalvular MR. Thirty days' outcome of first-in-man implants with a novel TMVI device is reported. METHODS: The Tendyne TMVI system consists of a porcine pericardial valve in a tethered nitinol frame...
May 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27534982/assessment-of-cardiovascular-disease-in-the-donkey-clinical-echocardiographic-and-pathological-observations
#12
S L Roberts, J Dukes-McEwan
The Donkey Sanctuary (DS) owns 3500-4000 donkeys, estimated to be about 35 per cent of the UK population. Although postmortem surveys suggest a high prevalence of cardiovascular disease in donkeys, there is sparse clinical information about cardiovascular examination findings and echocardiographic findings in health and disease. In this cross-sectional study, auscultation findings were recorded, and in a subset of donkeys, echocardiography was used to screen for structural and functional cardiac disease. 202 donkeys were examined; 117 geldings and 85 females...
October 15, 2016: Veterinary Record
https://www.readbyqxmd.com/read/27534757/children-with-post-rheumatic-valvulopathies-in-natural-history-five-years-follow-up-in-the-cardiac-centre-st-elizabeth-catholic-general-hospital-shisong-cameroon
#13
J C Tantchou Tchoumi, J C Ambassa, G Butera
The aim of the study was to investigate the pattern of valvular lesions, the mortality and the challenges in five years follow-up in children with post-rheumatic valvulopathies in natural history in St. Elizabeth Catholic General hospital Shisong, cardiac centre. This retrospective analysis included 270 patients aged between 5 and 16 years old suffering from post-rheumatic valvulopathies who consulted in the cardiac centre from July 2008 through July 2013. Postrheumatic valvulopathies were diagnosed according to the World heart federation criteria...
December 2016: Bulletin de la Société de Pathologie Exotique
https://www.readbyqxmd.com/read/27479126/pathological-investigation-of-congenital-bicuspid-aortic-valve-stenosis-compared-with-atherosclerotic-tricuspid-aortic-valve-stenosis-and-congenital-bicuspid-aortic-valve-regurgitation
#14
Yasuhiro Hamatani, Hatsue Ishibashi-Ueda, Toshiyuki Nagai, Yasuo Sugano, Hideaki Kanzaki, Satoshi Yasuda, Tomoyuki Fujita, Junjiro Kobayashi, Toshihisa Anzai
BACKGROUND: Congenital bicuspid aortic valve (CBAV) is the main cause of aortic stenosis (AS) in young adults. However, the histopathological features of AS in patients with CBAV have not been fully investigated. METHODS AND RESULTS: We examined specimens of aortic valve leaflets obtained from patients who had undergone aortic valve re/placement at our institution for severe AS with CBAV (n = 24, CBAV-AS group), severe AS with tricuspid aortic valve (n = 24, TAV-AS group), and severe aortic regurgitation (AR) with CBAV (n = 24, CBAV-AR group)...
2016: PloS One
https://www.readbyqxmd.com/read/27464536/-clinical-data-analysis-of-valvular-involvement-in-takayasu-arteritis
#15
N Gao, W P Ci, C Y Tian, J Du, Z J Zhou, T Wang
OBJECTIVE: To investigate the clinical features of valvular lesions in Takayasu's arteritis. METHODS: We analyzed 22 medical records of patients with Takayasu's arteritis and valvular lesions in Anzhen Hospital, Capital Medical University from January 2012 to January 2015. RESULTS: The spectrums of valvular involvements were aortic valve regurgitation (11, 50%), aortic valve stenosis (1, 4.5%), mitral valve regurgitation (1, 4.5%), mitral valve stenosis (1, 4...
July 19, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27435353/red-blood-cell-distribution-width-can-it-be-a-predictive-marker-for-long-term-valvular-involvement-in-children-with-acute-rheumatic-carditis
#16
M Kucuk, R Ozdemir, C Karadeniz, K Celegen, M Demirol, M M Yilmazer, T Mese, N Unal
INTRODUCTION: In this study, we aimed to evaluate Red blood cell distribution width (RDW) in patients with acute rheumatic carditis during the acute phase and after anti-inflammatory therapy. METHODS: Pediatric patients diagnosed with acute rheumatic carditis (ARC) between 2006 and 2014 and age- and sex-matched controls were retrospectively analyzed. At the time of diagnosis and after 2 months of medical therapy, we reviewed the obtained demographic features; echocardiographic data; complete blood count reports, including RDW; acute phase reactants, including C-reactive protein; and erythrocyte sedimentation rate values...
October 2016: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/27266500/-clinical-data-analysis-of-cardiovascular-involvement-in-behcet-s-disease
#17
N Gao, W Han, W P Ci, H Liao, J Du
OBJECTIVE: To analysis the clinical features of cardiovascular involvement in Behcet's disease. METHODS: We reviewed 35 medical records of Behcet's disease with cardiovascular lesions in Anzhen Hospital, Capital Medical University from January 2002 to January 2014. 77.1% patients (27/35) were male. The mean (x±s) age when cardiovascular diseases occur was 37.19±10.4 years in male and 36.0±8.6 years in female respectively. RESULTS: The clinical spectrum of cardiovascular abnormalities included valvular regurgitation (20, 57...
May 24, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27212978/valve-sparing-surgery-in-an-adult-patient-with-dextrocardia-and-annuloaortic-ectasia
#18
Rahmi Zeybek, Ahmet Bacaksiz, Rasul Sharifov, Emrah Sevgili, Yasin Ay
We report the case of a patient with situs inversus totalis, annuloaortic ectasia complicated by aortic insufficiency and mitral regurgitation which induced congestive heart failure. Both valvular lesions were repaired physiologically using aortic root sparing Yacoub 'remodeling' technique and mitral ring annuloplasty. Valve sparing techniques can be used effectively even in patients with complicated clinical scenarios (like dextrocardia and annuloaortic ectasia) to avoid the potential risks related to prosthetic valve implantation and lifelong anticoagulation therapy...
March 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/27175283/plasma-brain-natriuretic-peptide-concentrations-in-patients-with-valvular-heart-disease
#19
Vishal Sharma, Ralph A Stewart, Mildred Lee, Ruvin Gabriel, Niels Van Pelt, David E Newby, Andrew J Kerr
OBJECTIVE: Plasma brain natriuretic peptide (BNP) concentrations predict prognosis in patients with valvular heart disease (VHD), but it is unclear whether this directly relates to disease severity. We assessed the relationship between BNP and echocardiographic measures of disease severity in patients with VHD. METHODS: Plasma BNP concentrations were measured in patients with normal left ventricular (LV) systolic function and isolated VHD (mitral regurgitation (MR), n=33; aortic regurgitation (AR), n=39; aortic stenosis (AS), n=34; mitral stenosis (MS), n=30), and age-matched and sex-matched controls (n=39) immediately prior to exercise stress echocardiography...
2016: Open Heart
https://www.readbyqxmd.com/read/27170744/surgery-for-doubly-committed-ventricular-septal-defects
#20
Ahmad Mahir Shamsuddin, Yen Chuan Chen, Abdul Rahim Wong, Trong-Phi Le, Robert H Anderson, Antonio F Corno
OBJECTIVES: Doubly committed ventricular septal defects (VSDs) account for up to almost one-third of isolated ventricular septal defects in Asian countries, compared with only 1/20th in western populations. In our surgical experience, this type of defect accounted for almost three-quarters of our practice. To date, patch closure has been considered the gold standard for surgical treatment of these lesions. Our objectives are to evaluate the indications and examine the outcomes of surgery for doubly committed VSDs...
August 2016: Interactive Cardiovascular and Thoracic Surgery
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