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Soft tissue lymphoma

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https://www.readbyqxmd.com/read/28426850/second-primary-malignant-neoplasms-and-survival-in-adolescent-and-young-adult-cancer-survivors
#1
Theresa H M Keegan, Archie Bleyer, Aaron S Rosenberg, Qian Li, Melanie Goldfarb
Importance: Although the increased incidence of second primary malignant neoplasms (SPMs) is a well-known late effect after cancer, few studies have compared survival after an SPM to survival of the same cancer occurring as first primary malignant neoplasm (PM) by age. Objective: To assess the survival impact of SPMs in adolescents and young adults (AYAs) (15-39 years) compared with that of pediatric (<15 years) and older adult (≥40 years) patients with the same SPMs...
April 20, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28422548/epidemiological-profile-and-treatment-outcomes-in-young-adults-19-29-years-of-age-treated-for-cancer-in-a-tertiary-hospital-in-s%C3%A3-o-paulo-brazil
#2
Victor Hugo Fonseca de Jesus, Taynan Nunes Ribeiro, Ludmilla T Domingos Chinen, Vanessa Alves, Maria Paula Curado, Marcello Ferretti Fanelli
BACKGROUND: Worldwide, the incidence of cancer in young adults (20-39 years) is increasing, and represents an important cause of mortality in this age group. A retrospective study was undertaken to provide information that may lead to improved treatment outcomes. METHODS: Epidemiological, clinicopathological, treatment, and survival information were retrieved from the electronic database registry of a tertiary referral hospital in São Paulo, Brazil for patients 19-29 years of age diagnosed with cancer between January 2007 and December 2012...
April 19, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28412026/primary-bone-sarcomas-in-patients-over-40-years-of-age-a-retrospective-study-using-data-from-the-bone-tumor-registry-of-japan
#3
Akihito Nagano, Daichi Ishimaru, Yutaka Nishimoto, Haruhiko Akiyama, Akira Kawai
BACKGROUND: Optimal treatments of patients aged >40 years with osteosarcoma and Ewing sarcoma and of patients with other types of bone sarcoma have not yet been established. METHODS: The clinical characteristics of 746 patients with primary bone sarcomas aged >40 years listed in the nationwide tumor registry (Bone and Soft Tissue Tumor Registry of Japan) were investigated. Patients with Ewing sarcoma, conventional chondrosarcoma, multiple myeloma, and malignant lymphoma were excluded...
April 12, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28410600/primary-adrenal-non-hodgkin-lymphoma-a-case-report-and-review-of-the-literature
#4
Nanik Ram, Owais Rashid, Saad Farooq, Imran Ulhaq, Najmul Islam
BACKGROUND: Lymphomas are cancers that arise from the white blood cells and have been traditionally divided into two large subtypes: Hodgkin and non-Hodgkin lymphoma. B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma; almost 85% of patients with lymphoma have this variant. Lymphomas can potentially arise from any lymphoid tissue located in the body; however, primary adrenal non-Hodgkin lymphoma is extremely rare. We report the history, examination findings, and laboratory results of a 50-year-old man diagnosed with a primary left adrenal diffuse large B-cell lymphoma...
April 15, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28407803/orchitis-reveals-an-extragonadal-primary-mediastinal-thymic-seminoma-a-coincidence-or-not
#5
Athanasios Tampakis, Ekaterini Christina Tampaki, Christos Damaskos, Themistoklis Feretis, Irene Thymara, Konstantinos Kontzoglou, Periklis Tomos, Gregory Kouraklis
BACKGROUND: Mediastinal thymic seminomas are rare male germ cell tumors with extragonadal origin that appear predominately with a cystic appearance. CASE PRESENTATION: A 22-year-old male was referred to our department for further investigation of a mediastinal mass discovered incidentally during routine chest X-ray. The patient has denied any symptoms including dyspnea, chest pain, cough, fever, dysphagia, hemoptysis, weight loss, and weakness. His past medical history was remarkable for orchitis, for which he had undergone a bilateral testicular biopsy, without the latter however, indicating the presence of a germ cell tumor or a premalignant lesion...
April 13, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28405080/myeloid-sarcoma-causing-airway-obstruction
#6
Aaron R Belknap, John R Krause
Myeloid sarcoma is an extramedullary collection of blasts of the myeloid series that partially or totally effaces the architecture of the tissue in which it is found. These tumors have been described in many sites of the body, but the skin, lymph nodes, gastrointestinal tract, bone, soft tissue, and testes are most common. They can arise in a patient following the diagnosis of acute myeloid leukemia, but they may also be precursors of leukemia and should be considered diagnostic for acute myeloid leukemia. The differential diagnosis of this neoplasm includes malignant lymphoma, with which it is often mistaken, leading to diagnostic and therapeutic delays...
April 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28403103/primary-bone-lymphoma-of-radius-and-tibia-a-case-report-and-review-of-literature
#7
Yanmei Huan, Yiwei Qi, Weisheng Zhang, Jianguo Chu
RATIONALE: Primary bone lymphoma (PBL) is a rare malignant entity. There is a better survival of PBL than any other malignant bone tumors and extranodal lymphomas. PATIENT CONCERNS: We report a rare case of PBL involving radius and tibia. The patient was a 14-year-old girl with left forearm pain and swelling after trauma. Six months later after the last chemotherapy and radiotherapy, pain and swelling of left knee was presented. DIAGNOSES: Radiological imaging revealed a lytic destruction, periosteal reaction, and pathological fracture of radius and tibia with soft tissue mass...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28399341/lymphoproliferative-tumors-of-the-ocular-adnexa
#8
Robert M Verdijk
The ocular adnexa include the eyelids, conjunctiva, lacrimal apparatus, and orbital soft tissue. One percent of all lymphomas and approximately 8% of all extranodal lymphomas arise in the ocular adnexa and their incidence is increasing. Reactive lymphoid hyperplasia comprises 16% of all lymphoproliferative tumors of the ocular adnexa. The relative frequencies of ocular adnexal lymphoma presentation are in the orbit, 37%; conjunctiva, 29%; lacrimal apparatus, 20%; and eyelid, 14%. The most frequent primary lymphoma types of the ocular adnexa are extranodal marginal zone lymphoma, 62%; follicular lymphoma, 17%; and diffuse large B-cell lymphoma, 10%...
March 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28381153/alk-negative-anaplastic-large-cell-lymphoma-presenting-as-an-extranodal-soft-tissue-mass-with-an-unusual-alveolar-growth-pattern
#9
Badr AbdullGaffar, Rania M Seliem
Anaplastic large cell lymphoma (ALCL) is a T-cell lymphoma which has been recognized to have a variable clinical presentation and a broad spectrum of histomorphologic features. Its variable histomorphologic appearances are sometimes diagnostically challenging for the pathologists since they can mimic sarcomas, melanomas and undifferentiated carcinomas. To our knowledge, a previous case of axillary soft-tissue mass of ALK-positive ALCL with an alveolar growth pattern has been so far reported in the literature...
March 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28377138/daily-ct-guidance-improves-target-coverage-during-definitive-radiation-therapy-for-gastric-malt-lymphoma
#10
He Wang, Sarah A Milgrom, Bouthaina S Dabaja, Grace L Smith, Mary Martel, Chelsea C Pinnix
PURPOSE: Radiation therapy (RT) for gastric mucosa-associated lymphoid tissue (MALT) lymphoma is challenging because of variation in the stomach's position, size, and shape. We investigated the interfractional changes in stomach location, consequent dosimetric effects, and impact of daily computed tomography image guidance RT (CT-IGRT). METHODS AND MATERIALS: Twelve patients treated for gastric MALT lymphoma with intensity modulated radiation therapy, using a breath-hold technique and restriction of oral intake, were studied retrospectively...
March 6, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28376906/braf-v600e-expression-in-histiocytic-sarcoma-associated-with-splenic-marginal-zone-lymphoma-a-case-report
#11
John L Vaughn, C Eric Freitag, Jessica A Hemminger, Jeffrey A Jones
BACKGROUND: Histiocytic sarcoma is a rare histiocytic neoplasm of unknown etiology that constitutes less than 1% of hematologic malignancies. A few cases of histiocytic sarcoma harboring the BRAF (V600E) mutation have been reported, but this finding has not been confirmed in all studies. CASE PRESENTATION: We report the case of a 63-year-old white woman with a history of splenic marginal zone lymphoma who presented with 2 weeks of right-sided neck swelling. Positron emission tomography revealed an intensely hypermetabolic and destructive soft tissue mass in her right skull base...
April 5, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28372572/distal-appendicular-skeletal-involvement-of-diffuse-large-b-cell-lymphoma-on-technetium-99m-methylenediphosphonate-bone-scintigraphy-and-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-a-case-report
#12
Insook Park, Sungmin Kang
BACKGROUND: We report a case of a patient with appendicular bone involvement of diffuse large B-cell lymphoma visualized by whole-body technetium-99m methylenediphosphonate bone scintigraphy (bone scan) and (18)F-fluorodeoxyglucose positron emission tomography/computed tomography. CASE PRESENTATION: A 73-year-old Asian man who had gingival swelling of the labial area of the left maxillary lateral incisor presented to our institution. Positron emission tomography/computed tomography demonstrated hypermetabolic lesions with maximum standardized uptake values of 12...
April 4, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28344538/surgical-excision-of-mycosis-fungoides-using-thumb-sparing-reconstruction
#13
Giancarlo McEvenue, Ashley Kim, Paul Binhammer
Background: The differential for soft tissue tumors of the hand and upper limb is broad. Hematologic malignancy remains quite low on the differential for soft tissue tumors involving the hand, and there is little in the literature describing surgical management of such cutaneous manifestations. When the tumor is large or involves the thumb, careful consideration of reconstructive options is required. Methods: We present a rare case of an aggressively enlarging mycosis fungoides, a cutaneous T-cell lymphoma tumor, involving the thumb...
March 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28328599/burkitt-lymphoma-in-adult-with-atypical-clinical-presentation-primarily-involving-the-oral-soft-tissue
#14
Natália Galvão Garcia, Moacyr Tadeu Vicente Rodrigues, Rodrigo Queiroz Aleixo, Denise Tostes Oliveira
Non-Hodgkin lymphoma is the second most common neoplasm of the head and neck after squamous cell carcinoma. However, it accounts for only 3.5% of all malignancies of the oral cavity. Oral lesions are often a component of disseminated disease process that may involve regional lymph nodes or may at times represent the primary extra nodal form of the disease. Although, isolated oral lymphoma in adults is extremely rare, this paper presents a patient with Burkitt lymphoma in an adult male with atypical clinical presentation primarily involving the oral soft tissue...
March 21, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28303852/differentiation-of-lymphoma-presenting-as-retroperitoneal-mass-and-retroperitoneal-fibrosis-evaluation-with-multidetector-row-computed-tomography
#15
Shuai Zhang, Min Chen, Chun-Mei Li, Guo-Dong Song, Ying Liu
BACKGROUND: Retroperitoneal fibrosis (RPF) and lymphoma presenting as retroperitoneal mass may closely resemble each other and misdiagnosis may occur. This study investigated the differential imaging features of RPF and lymphoma which presented as a retroperitoneal soft tissue using multidetector-row computed tomography (MDCT). METHODS: The 42 consecutive patients were included in this retrospective review, including 19 RPF patients (45.2%; including 13 males and 6 females; mean age: 56...
March 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28292479/costs-for-childhood-and-adolescent-cancer-90-days-prediagnosis-and-1-year-postdiagnosis-a-population-based-study-in-ontario-canada
#16
Claire de Oliveira, Karen E Bremner, Ning Liu, Mark L Greenberg, Paul C Nathan, Mary L McBride, Murray D Krahn
BACKGROUND: Childhood and adolescent cancers are uncommon, but they have important economic and health impacts on patients, families, and health care systems. Few studies have measured the economic burden of care for childhood and adolescent cancers. OBJECTIVES: To estimate costs of cancer care in population-based cohorts of children and adolescents from the public payer perspective. METHODS: We identified patients with cancer, aged 91 days to 19 years, diagnosed from 1995 to 2009 using cancer registry data, and matched each to three noncancer controls...
March 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28291146/malignant-lymphoma-mimicking-an-infection-after-shoulder-surgery
#17
Jabari Ian Justin Martin, Jasmine Bauknight, Vincent Desiderio, Bahman Sadr
Involvement of the musculoskeletal system by primary or metastatic malignant neoplasms mimicking common orthopaedic conditions is well recognized. The diagnosis may be delayed in the absence of radiographic abnormalities. Twenty-five percent of lymphoma cases have skeletal involvement, and they can affect both bone and soft tissue. Lymphoma is sometimes discovered by means of routine histologic examination of tissue collected at the time of orthopaedic surgery. To the best of our knowledge, this is the first report of lymphoma occurring at the site of prior shoulder surgery and mimicking an infection...
April 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28287948/spectrum-of-ct-findings-in-thoracic-extranodal-non-hodgkin-lymphoma
#18
Mathew P Bligh, Joy N Borgaonkar, Steven C Burrell, David A MacDonald, Daria Manos
Non-Hodgkin lymphoma (NHL) frequently manifests in extranodal structures in the chest, often in the form of secondary involvement but occasionally as primary disease. Because staging and treatment are affected by the presence of extranodal disease at imaging, radiologists' interpretation and management of suspicious findings are critical to patient care. Unfortunately, owing to considerable imaging overlap with other diseases, primary extranodal lymphoma is difficult to diagnose with imaging alone. Radiologists should have a heightened degree of suspicion in patients at risk (including patients with immune compromise, autoimmune diseases, or a history of stem cell or solid organ transplant) or with particular imaging appearances (including the vertebral wraparound sign, nonresolving consolidation, an infiltrative soft-tissue mass, and lesions demonstrating vascular encasement without invasion)...
March 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28272651/subcutaneous-leiomyosarcoma-metastasized-to-the-lymph-nodes-involved-with-small-lymphocytic-lymphoma-chronic-lymphocytic-leukemia
#19
Ayfer Kamali Polat, Atilla Soran, Amal Kanbour-Shakir, Howard Edington
Herein, we present a case of a 76-year-old Caucasian man with a very large fungating, ulcerating mass, involving the right neck and parotid area, which developed while he was being treated for chronic lymphocytic leukemia/small lymphocytic lymphoma. Resection of the fungating right neck tumor, right modified radical neck dissection, and right superficial parotidectomy with flap reconstruction were performed. The final pathological diagnosis was high-grade leiomyosarcoma of the skin and the subcutaneous tissue, with invasion into the skeletal muscle, skin, and soft tissue...
February 4, 2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28257637/access-to-principal-treatment-centres-and-survival-rates-for-children-and-young-people-with-cancer-in-yorkshire-uk
#20
Lesley Fairley, Daniel P Stark, Daniel Yeomanson, Sally E Kinsey, Adam W Glaser, Susan V Picton, Linda Evans, Richard G Feltbower
BACKGROUND: Principal Treatment Centres (PTC) were established to provide age-appropriate care as well as clinical expertise for children and young people with cancer. However, little is known about the effects of specialist treatment centres on survival outcomes especially for teenagers and young adults. This population-based study aimed to describe access to PTC and the associated trends in survival for 0-24 year olds accounting for stage of disease at presentation and treatment. METHODS: Patients diagnosed from 1998-2009 aged 0-24 years were extracted from the Yorkshire Specialist Register of Cancer in Children and Young People, including information on all treating hospitals, followed-up until 31st December 2014...
March 4, 2017: BMC Cancer
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