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https://www.readbyqxmd.com/read/29207114/elderly-apolipoprotein-e%C3%A2-%C3%A2-mice-with-advanced-atherosclerotic-lesions-in-the-aorta-do-not-develop-alzheimer-s-disease-like-pathologies
#1
Reut Shnerb Ganor, Dror Harats, Ginette Schiby, Kinneret Rosenblatt, Irit Lubitz, Aviv Shaish, Ophira Salomon
Atherosclerosis and Alzheimer's disease (AD) are a major cause of morbidity and mortality in Western societies. These diseases share common risk factors, which are exhibited in old age, including hypertension, diabetes, hypercholesterolemia and apolipoprotein (Apo) ε4 allele. We previously demonstrated that factor XI (FXI) deficiency in mice reduced the atherosclerotic plaque area in coronary sinuses and the aortic arch. This led us to investigate whether FXI deficiency in elderly ApoE knockout (KO) mice would decrease pathological alterations compatible with atherosclerosis and AD...
November 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29187942/-double-aortic-arch-about-two-cases
#2
Sihame Lemouakni, Amale Hassani, Hakim Elyajouri, Mohammed Kmari, Hakim Ourrai, Rachid Abilkacem, Aomar Agadr
Double aortic arch is a rare anomaly of the aortic arch. It is due to the absence of involution of the caudal dorsal aorta. The disease usually begins to show itself in very early clinical signs, already detectable in the neonatal period. Angiography is of great interest to its diagnosis as well as to the choice of the therapeutic approach. Only surgical treatment allows to eliminate tracheoesophageal compression. Surgical mortality rate is low thanks to the progress of postoperative resuscitation. We here report two cases of double aortic arch in order to highlight the contribution of imaging in the difficult diagnosis of this anomaly...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29174590/double-outlet-right-ventricle-with-subpulmonary-ventricular-septal-defect-taussig-bing-anomaly-and-other-complex-congenital-cardiac-malformations-in-an-american-quarter-horse-foal
#3
Rebecca Kohnken, Karsten Schober, Jennifer Godman, Alison Gardner, Tiffany Jenkins, Eric Schroeder, Peter Baker, Laura Dunbar
A 4-week-old American Quarter Horse colt presented with a recent history of diarrhea and decreased activity level. On initial physical examination, the animal was bright and alert and major findings were limited to a loud systolic heart murmur radiating widely over both sides of the thorax. While in the hospital, the clinical condition of the foal warranted further imaging to determine the cause and extent of cardiac disease. A variety of congenital cardiac malformations were identified during echocardiographic examination and autopsy, including a double outlet right ventricle and a subpulmonary interventricular septal defect (Taussig-Bing anomaly), ventricular inversion with atrioventricular discordance, tricuspid valve atresia, a septum primum interatrial septal defect, mitral valve dysplasia with a cleft in the septal mitral valve cusp, aortic, and subaortic stenosis, tubular hypoplasia of the ascending aorta and the aortic arch, a patent ductus arteriosus, an aberrant circumflex coronary artery, and aberrant left and right subclavian arteries...
November 21, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/29174374/tracheobronchial-stenting-for-airway-malacia
#4
REVIEW
Colin Wallis, Clare A McLaren
Tracheobronchomalacia is a rare but clinically troublesome condition in paediatrics. The softening of the major airways - which can include some or all of the tracheobronchial tree can lead to symptoms ranging from the minor (harsh barking cough, recurrent chest infections) to severe respiratory difficulties including prolonged ventilator support and 'near death attacks'. The causes are broadly divided into intrinsic softening of the airway wall which is considered a primary defect (e.g. syndromes; post tracheo-oesophageal fistula repair; extreme prematurity) or secondary malacia due to external compression from vascular structures or cardiac components...
October 13, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/29173997/the-impact-of-different-torques-for-the-insertion-of-immediately-loaded-implants-on-the-peri-implant-levels-of-angiogenesis-and-bone-related-markers
#5
A Verrastro Neto, R Andrade, M G Corrêa, R C V Casarin, M Z Casati, S P Pimentel, F V Ribeiro, F R Cirano
The aim of this split-mouth, randomized, double-blind, controlled clinical trial was to evaluate the influence of different insertion torque values for dental implants on bone- and angiogenesis-related marker profiles. Eighteen edentulous patients received dental implants and fixed complete-arch mandibular prostheses. The implants (n=36) were assigned randomly to two groups: reduced torque (n=18), with insertion torque <30Ncm; and conventional torque (n=18), with insertion torque ≥30Ncm. Levels of vascular endothelial growth factor (VEGF), placental growth factor, bone morphogenetic protein 9 (BMP-9), periostin, osteoprotegerin (OPG), and tartrate-resistant acid phosphatase (TRAP) in the peri-implant fluid were quantified at 7, 14, 30, and 120days after implant placement...
November 22, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29173856/changes-of-bite-force-and-occlusal-contacts-in-the-retention-phase-of-orthodontic-treatment-a-controlled-clinical-trial
#6
Suzana Varga, Stjepan Spalj, Sandra Anic Milosevic, Marina Lapter Varga, Senka Mestrovic, Magda Trinajstic Zrinski, Mladen Slaj
INTRODUCTION: We aimed to determine whether appliance type affects changes in maximum voluntary bite force (MVBF) and the number of occlusal contacts (NOC) during retention, controlling for sex, age, and body mass index. METHODS: The sample comprised 176 examinees (70 male, 106 female) aged 14 to 20 years: 30 had maxillary and mandibular Essix retainers, 30 had wrap-around retainers, and 30 had a combination of fixed mandibular canine-to-canine retainers bonded on each tooth separately (double twisted, 0...
December 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/29082655/immediately-restored-full-arch-fixed-prosthesis-on-implants-placed-in-both-healed-and-fresh-extraction-sockets-after-computer-planned-flapless-guided-surgery-a-3-year-follow-up-study
#7
Giampiero Ciabattoni, Alessandro Acocella, Roberto Sacco
BACKGROUND: The treatment of patients by the use of immediate implant placement in post-extractive site is a challenging procedure. PURPOSE: A 3-year clinical and radiological study of post-extractive implants placed using flapless guided surgery and immediately functioning. MATERIALS AND METHODS: Thirty-two patients (23 females and 9 males), aged between 44 and 73 years (a mean age of 59.5) were treated with immediate full arch restorations and flapless implant surgery in fresh extraction and healed sites...
October 29, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29061187/elevated-microrna-129-5p-level-ameliorates-neuroinflammation-and-blood-spinal-cord-barrier-damage-after-ischemia-reperfusion-by-inhibiting-hmgb1-and-the-tlr3-cytokine-pathway
#8
Xiao-Qian Li, Feng-Shou Chen, Wen-Fei Tan, Bo Fang, Zai-Li Zhang, Hong Ma
BACKGROUND: Ischemia-reperfusion (IR) affects microRNA (miR) expression and causes substantial inflammation. Multiple roles of the tumor suppressor miR-129-5p in cerebral IR have recently been reported, but its functions in the spinal cord are unclear. Here, we investigated the role of miR-129-5p after spinal cord IR, particularly in regulating high-mobility group box-1 (HMGB1) and the Toll-like receptor (TLR)-3 pathway. METHODS: Ischemia was induced via 5-min occlusion of the aortic arch...
October 23, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29033732/double-aortic-arch-presenting-with-respiratory-distress-a-case-report-and-review-of-the-literature
#9
Abdelhafid Houba, Mustapha Bensghir, Redouane Ahtil, Badr Slioui, Hicham Balkhi, Salim Jaafar Lalaoui
Tracheal compression by vascular structures in infants is uncommon and may be masked by nonspecific respiratory symptoms. Double aortic arch (DAA) is the most common vascular ring. We describe a case of a 9-month-old male infant presented with respiratory distress and found to have a DAA. In this report, the authors emphasize the consideration of this pathology-induced respiratory distress and discuss its anesthetic management.
October 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28944358/ceramic-vs-composite-veneering-of-full-arch-implant-supported-zirconium-frameworks-assessing-patient-preference-and-satisfaction-a-crossover-double-blind-randomised-controlled-trial
#10
Mauro Merli, Eugenio Bianchini, Giorgia Mariotti, Marco Moscatelli, Matteo Piemontese, Giorgio Rappelli, Michele Nieri
PURPOSE: The objectives of this two-period, crossover, mono-centred, double-blind, randomised controlled trial (RCT) were to compare two different materials used for full arch implant-supported prosthetic restorations with regard to patient preference and impact on a patient's quality of life. MATERIALS AND METHODS: Edentulous patients requesting one full arch restoration in the mandible or maxilla supported by dental implants were included in this study. Patients were randomised to receive either a full arch zirconia framework hand-veneered with ceramic, or a full arch zirconia framework hand-veneered with composite material...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28936103/double-c1-posterior-arches
#11
Pralaya Kishore Nayak
No abstract text is available yet for this article.
August 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28933235/aortopexy-for-life-threatening-airway-obstruction-following-division-of-double-aortic-arch
#12
Katrina Hammond-Jack, Karthik Vaidyanathan Ramakrishnan, Dilip S Nath
Symptoms of airway compression secondary to double aortic arch are relieved by division of one of the two aortic arches. However, in some cases inherent tracheomalacia and other factors may result in persistence of symptoms. We report one such occurrence in our experience and describe the use of aortopexy as a curative procedure to tackle this problem.
January 1, 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28906510/retrospective-analysis-on-survival-rate-template-related-complications-and-prevalence-of-peri-implantitis-of-694-anodized-implants-placed-using-computer-guided-surgery-results-between-1-and-10-years-of-follow-up
#13
Marco Tallarico, Silvio Mario Meloni
PURPOSE: To report survival rate, early surgical template-related complications, and prevalence of peri-implantitis of dental implants placed in private practices using computer-guided, template-assisted surgery and followed between 1 and 10 years. MATERIALS AND METHODS: The present retrospective multicenter study evaluated data collected from fully or partially edentulous patients, with anodized-surface implants placed using computer-guided, template-assisted surgery between January 2006 and December 2015...
September 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28885582/effect-of-vertical-shoot-positioned-scott-henry-geneva-double-curtain-arch-cane-and-parral-training-systems-on-the-volatile-composition-of-albari%C3%A3-o-wines
#14
Mar Vilanova, Zlatina Genisheva, Miguel Tubio, Katia Álvarez, Jose Ramón Lissarrague, José Maria Oliveira
Viticultural practices influence both grape and wine quality. The influence of training systems on volatile composition was investigated for Albariño wine from Rías Baixas AOC in Northwest Spain. The odoriferous contribution of the compounds to the wine aroma was also studied. Volatile compounds belonging to ten groups (alcohols, C₆-compounds, ethyl esters, acetates, terpenols, C13-norisoprenoids, volatile phenols, volatile fatty acids, lactones and carbonyl compounds) were determined in Albariño wines from different training systems, Vertical Shoot-Positioned (VSP), Scott-Henry (SH), Geneva Double-Curtain (GDC), Arch-Cane (AC), and Parral (P) during 2010 and 2011 vintages...
September 8, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28854527/3d-imaging-evaluation-of-double-aortic-arch-with-mscta-a-case-report-and-mini-review
#15
Xu Zhu, Chun Wu, Yun He, Bin Qin, Haiyan Yang, Hong Huang, Xiaojuan Ji
Double aortic arch (DAA) is a rare congenital anomaly associated with the formation of a vascular ring. Patients with DAA commonly suffer from complications caused by intracardiac and extracardiac malformations and different degrees of airway stenosis. Multislice computed tomographic angiography (MSCTA) is an intuitive and effective medical imaging technique in clinical diagnosis of DAA. MSCTA can accurately manifest the aortic arch and the course of the descending aorta and airway stenosis in three-dimension (3D)...
August 24, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/28852840/biomechanical-study-of-novel-unilateral-c1-posterior-arch-screws-and-c2-laminar-screws-combined-with-an-ipsilateral-crossed-c1-c2-pedicle-screw-rod-fixation-for-atlantoaxial-instability
#16
Kai Shen, Zhongliang Deng, Junsong Yang, Chao Liu, Ranxi Zhang
INTRODUCTION: Current surgical methods to treat atlantoaxial instability pose potential risks to the surrounding blood vessels and nerves of operative approach. Therefore, more secure and highly effective methods are expected. This study sought to assess the biomechanical efficacy of a novel unilateral double screw-rod fixation system by comparing with traditional and emerging fixation methods in cadaveric models. MATERIALS AND METHODS: Ligamentous cervical spines (C0-C7) from ten fresh cadaveric specimens were used to complete range of motion (ROM) test in their intact condition (control group), destabilization, and stabilization after different fixations, including unilateral C1-C2 pedicle screws (PS) with a screw-rod system (Group A), bilateral C1-C2 PS with screw-rod systems (Group B), unilateral C1 posterior arch screws (PAS) and C2 laminar screws (LS) combined with an ipsilateral paralleled C1-C2 PS-rod (Group C), and unilateral C1 PAS and C2 LS combined with an ipsilateral crossed C1-C2 PS-rod (Group D)...
August 29, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28851468/persistent-fifth-aortic-arch-the-great-pretender-in-clinical-practice
#17
David F A Lloyd, S Y Ho, Kuberan Pushparajah, Subhasis Chakraborty, Mohamed Nasser, Hideki Uemura, Rodney Franklin, Alan G Magee
Persistence of the embryonic "fifth aortic arch" in postnatal life is a rare, enigmatic - and at times controversial - condition, with variable anatomical forms and physiological consequences. First described in humans over 40 years ago by Van Praagh, the condition was labelled the "great pretender" by Gerlis 25 years later, because of its apparent propensity to mimic anatomically similar structures. Despite many subsequent case reports citing the condition, the true developmental origin of these structures remains unresolved, and has been the subject of debate among embryologists for more than a century...
August 30, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28843327/role-of-computational-modelling-in-planning-and-executing-interventional-procedures-for-congenital-heart-disease
#18
REVIEW
Timothy C Slesnick
Increasingly, computational modelling and numerical simulations are used to help plan complex surgical and interventional cardiovascular procedures in children and young adults with congenital heart disease. From its origins more than 30 years ago, surgical planning with analysis of flow hemodynamics and energy loss/efficiency has helped design and implement many modifications to existing techniques. On the basis of patient-specific medical imaging, surgical planning allows accurate model production that can then be manipulated in a virtual surgical environment, with the proposed solutions finally tested with advanced computational fluid dynamics to evaluate the results...
September 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28843154/numerical-analysis-of-wall-shear-stress-in-ascending-aorta-before-tearing-in-type-a-aortic-dissection
#19
Qingzhuo Chi, Ying He, Yong Luan, Kairong Qin, Lizhong Mu
Although the incidence of many cardiovascular diseases has declined as medical treatments have improved, the prevalence of aortic dissection (AD) has increased. Compared to type B dissections, type A dissections are more severe, and most patients with type A dissections require surgical treatment. The objective of this study was to investigate the relationships between the wall shear stress (WSS) on the aortic endothelium and the frequent tearing positions using computational fluid dynamics. Five type A dissection cases and two normal aortas were included in the study...
August 1, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28840674/-case-report-comprehensive-treatment-of-forefoot-with-double-brachymetatarsia-in-one-surgical-stage
#20
I Caldiño-Lozada, O Gallegos-de la Torre, R Esperón-Hernández
Brachymetatarsia (shortening of the metatarsal) directly affects the transversal arch of the foot causing severe deformities, such as hallux valgus, divergent toes, overlapping toes, metatarsalgia, all of these alter the biomechanics of the foot and gait. Treatment consists of two main techniques, one-stage lengthening with bone graft or elongation through callotaxis with external fixator; there are variants of both techniques used to minimize the disadvantages of each. The objective of treatment must be to return the structural harmony to the forefoot, improving the biomechanics, resulting in a satisfactory outcome for the patients...
March 2017: Acta Ortopédica Mexicana
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