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Foetal cardiology

Olga Panagiotopoulou, Sotirios Fouzas, Xenophon Sinopidis, Stefanos P Mantagos, Gabriel Dimitriou, Ageliki A Karatza
BACKGROUND: Increased incidence of congenital heart disease (CHD) has been reported in the offspring of monochorionic twin gestations. Assisted reproductive technology (ART), which is related to increased rates of twinning, has also been associated with higher risk of birth defects. We studied the incidence of CHD in a cohort of twins to clarify the contribution of type of conception and chorionicity. METHODS: Data concerning 874 live-born twins of which at least one was admitted in our Neonatal Unit during 1995-2012 were analysed...
September 1, 2016: International Journal of Cardiology
Ewa-Lena Bratt, Stina Järvholm, Britt-Marie Ekman-Joelsson, Lars-Åke Mattson, Mats Mellander
BACKGROUND: Prenatal screening for foetal cardiac abnormalities has been increasingly practiced in Sweden during the last 25 years. A prenatal diagnosis may have medical benefits but may also cause sustained parental psychological distress. The aim of this study was to explore pregnant women's, and their partner's, experiences of counselling and need for support during continued pregnancy following a prenatal diagnosis of a cardiac defect. A second aim was to use this information to propose a structured follow-up programme for continued support after the first counselling...
2015: BMC Pregnancy and Childbirth
Mats Mellander, Helena Gardiner
The update course in foetal cardiology held by the Fetal Working Group of the Association for European Paediatric and Congenital Cardiology in Istanbul in May 2012 included a session on foetal cardiac therapy. In the introductory overview to this symposium, we critically examine the level of evidence supporting or refuting proposed foetal cardiac therapies including transplacental treatment of foetal tachyarrhythmias, steroid treatment in foetal atrioventricular block, and foetal aortic valvuloplasty. In summary, the evidence for the efficiency and safety of currently available foetal cardiac therapies is low, with no therapy based on a randomised controlled trial...
October 2014: Cardiology in the Young
Dick Oepkes, Monique Haak
Foetal echocardiography has become an established subspecialty in paediatric cardiology. The skills to perform detailed assessment of foetal cardiac anomalies in a tiny, moving foetus surrounded by sometimes challenging layers of maternal tissue are not easy to obtain, and require prolonged periods of specific training and supervised scanning in expert centres. The goal of this overview is to discuss the importance of the awareness of the fact that expert examination of the foetal heart and in-depth knowledge of newborn surgical interventions are only a part of the picture; many cardiac abnormal foetuses do not just have an isolated cardiac defect...
October 2014: Cardiology in the Young
Joachim Behar, Fernando Andreotti, Sebastian Zaunseder, Qiao Li, Julien Oster, Gari D Clifford
Accurate foetal electrocardiogram (FECG) morphology extraction from non-invasive sensors remains an open problem. This is partly due to the paucity of available public databases. Even when gold standard information (i.e derived from the scalp electrode) is present, the collection of FECG can be problematic, particularly during stressful or clinically important events.In order to address this problem we have introduced an FECG simulator based on earlier work on foetal and adult ECG modelling. The open source foetal ECG synthetic simulator, fecgsyn, is able to generate maternal-foetal ECG mixtures with realistic amplitudes, morphology, beat-to-beat variability, heart rate changes and noise...
August 2014: Physiological Measurement
Joachim Behar, Julien Oster, Gari D Clifford
Despite significant advances in adult clinical electrocardiography (ECG) signal processing techniques and the power of digital processors, the analysis of non-invasive foetal ECG (NI-FECG) is still in its infancy. The Physionet/Computing in Cardiology Challenge 2013 addresses some of these limitations by making a set of FECG data publicly available to the scientific community for evaluation of signal processing techniques.The abdominal ECG signals were first preprocessed with a band-pass filter in order to remove higher frequencies and baseline wander...
August 2014: Physiological Measurement
A Old, R Arya, K Macleod, A Verma, P Chattington
: CMACE 2008 has shown that the overall rate of mortality from cardiac disease has tripled over the last two decades being, the largest cause of indirect maternal death; mainly due to acquired heart disease. With the current increase in older mothers, obesity, immigration and survival of babies operated on for congenital heart disease, the need to identify women at risk of heart disease and to plan their careful management is crucial. Early identification of risk factors include hypertension, pre-eclampsia, diabetes, smoking, obesity and hyperlipidaemia and a multidisciplinary management improves maternal and foetal outcomes...
June 2014: Archives of Disease in Childhood. Fetal and Neonatal Edition
Victoria C Jowett, Srividhya Sankaran, Sherrida L Rollings, Richard Hall, Pippa M Kyle, Gurleen K Sharland
OBJECTIVES: The aim of this study was to determine the timing of neonatal cardiac intervention in babies with antenatally diagnosed congenital heart disease and the impact on obstetric management. METHODS: A retrospective review of all deliveries between January, 2008 and December, 2009 was conducted in a tertiary centre with foetal and paediatric cardiology, maternal-foetal medicine, and obstetric units. All live births with antenatally detected congenital heart disease were included...
June 2014: Cardiology in the Young
Jolien W Roos-Hesselink, Titia P E Ruys, Jörg I Stein, Ulf Thilén, Gary D Webb, Koichiro Niwa, Harald Kaemmerer, Helmut Baumgartner, Werner Budts, Aldo P Maggioni, Luigi Tavazzi, Nasser Taha, Mark R Johnson, Roger Hall
AIMS: To describe the outcome of pregnancy in patients with structural or ischaemic heart disease. METHODS AND RESULTS: In 2007, the European Registry on Pregnancy and Heart disease was initiated by the European Society of Cardiology. Consecutive patients with valvular heart disease, congenital heart disease, ischaemic heart disease (IHD), or cardiomyopathy (CMP) presenting with pregnancy were enrolled. Data for the normal population were derived from the literature...
March 2013: European Heart Journal
Giuseppe Mercuro, Pier Paolo Bassareo, Giovanna Flore, Vassilios Fanos, Ilaria Dentamaro, Pietro Scicchitano, Nicola Laforgia, Marco Matteo Ciccone
Although the survival rate for preterm subjects has improved considerably, due to the progress in the field of perinatal medicine, preterm birth is frequently the cause underlying a series of notorious complications: morphological, neurological, ophthalmological, and renal alterations. In addition, it has recently been demonstrated how low gestational age and reduced foetal growth contribute towards an increased cardiovascular risk in preterm neonates. In fact, cardiovascular mortality is higher among former preterm adults than those born at term...
April 2013: European Journal of Preventive Cardiology
Maboury Diao, Adama Kane, Mouhamadou Bamba Ndiaye, Alassane Mbaye, Malick Bodian, Mouhamadoul Mounir Dia, Moustapha Sarr, Abdoul Kane, Jean-Jacques Monsuez, Serigne Abdou Ba
BACKGROUND: Although previous studies showed that pregnancy with heart disease is associated with significant complications, few focused on patients with valvular heart disease in sub-Saharan Africa. METHODS: We report maternal and foetal outcomes in 50 pregnant women with heart disease admitted to the Department of Cardiology of the University of Dakar, during an 8-year period. RESULTS: Rheumatic heart disease was observed in 46 women, seven of whom had previously been operated on...
June 2011: Archives of Cardiovascular Diseases
Senka Dinarević
Thanks to embryological knowledge, morphological anatomy and segmental analysis, paediatric cardiology is today an exact science. Modern diagnostically and therapeutical approach in paediatric cardiology allows early application of foetal echocardiography in order of achieving diagnosis of congenital heart anomalies in utero. Diagnostic modalities in paediatric cardiology are represented the application of transthoracic echocardiography, transoesophageal, 3D and in recent years 4D echocardiography with possibilities of heart imaging via magnetic resonance and computerised tomography...
2007: Medicinski Arhiv
Paweł Własienko, Anita Hamela-Olkowska, Katarzyna Jalinik, Joanna Dangel
OBJECTIVE: To assess the possibility of foetal circulatory system evaluation between 11+0 to 13+6 weeks of gestation in a reference perinatal cardiology centre. MATERIAL AND METHODS: A prospective study was conducted between January 2004 and June 2008 in patients admitted to the reference perinatal cardiology centre for a foetal echocardiographic examination. 1170 foetuses were examined: 31 in 2004, 167 in 2005, 310 in 2006, 406 in 2007 and 262 in the first half of 2008...
April 2009: Ginekologia Polska
Peter H Gray, Cameron Ward, Fung-Yee Chan
AIM: To determine cardiac outcomes of foetal hydrops as a result of twin-twin transfusion syndrome treated with laser surgery. METHODS: Hydrops identified in 16 recipient foetuses with twin-twin transfusion syndrome was treated with laser ablation surgery to anastomotic vessels. Prior to laser surgery, the foetuses were assessed by echocardiography for cardiac abnormalities and ventricular and valvular dysfunction. After delivery, echocardiography was performed on 15 of the 16 newborn infants...
January 2009: Journal of Paediatrics and Child Health
N Chevalier, B Bständig, M -B Galand-Portier, V Isnard, A Bongain, P Fénichel
Turner's syndrome is characterized by an ovarian failure, which occurs in most cases before puberty and leads to infertility. In vitro fertilization with oocyte donation has dramatically transformed the prognosis of infertility of these women. However, in the same time, it has become obvious that pregnancies in Turner's syndrome are at very high risk of possible sudden death because of a specific risk for cardiovascular complications involving aortic root dissection. We report the case of a serious cardiac failure occurred during a twin pregnancy obtained by oocyte donation in a 39-year-old patient with Turner's syndrome...
September 2009: Annales D'endocrinologie
Martial M Massin, Houssem Masmoudi, Hugues Dessy, Michel Goor, Karim Khaldi, Marielle Morissens, Gilles Rondia, Pierre Viart
BACKGROUND: Few data are available on the evolution in the number of referrals and the spectrum and frequency of issues addressed in paediatric cardiac outpatient clinics. AIM: To assess the volume and range of symptoms and diagnoses in patients, referred to a paediatric cardiac outpatient clinic in an academic hospital setting. METHODS: Data were collected prospectively over 6 months. RESULTS: Historical comparison showed that the number of outpatient visits increased from 819 during the first semester of 2004 to 865, 1045 and 1391 during the first semesters of 2005, 2006 and 2007, respectively...
November 2008: Archives of Cardiovascular Diseases
M Mbaye, P-M Moreira, S M K Guèye, C T Cissé, J-C Moreau, A Kane, M Diao
OBJECTIVE: The persistence of the rheumatic valvular cardiopathie and the access to cardiac surgery make this association frequent. This work will deal with a description of the epidemiological and clinic profile and the evaluation of the cares to the pregnancies with cardiac valvular prostheses. METHODOLOGY: We took a retrospective study beginning from 1987 to 2006 about 14 cases, which had benefited from collaboration between the Gynaecologic and Obstetric Clinic and the Cardiological Clinic of the University Hospital Center of Dakar...
February 2009: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
Fedro A Peccatori, Hatem A Azim, Giovanna Scarfone, Angiolo Gadducci, Cristina Bonazzi, Oreste Gentilini, Viviana Galimberti, Mattia Intra, Marzia Locatelli, Barbara Acaia, Piero Rossi, Saverio Cinieri, Liliana Calabrese, Aron Goldhirsch
BACKGROUND: GBC is a rare disease and chemotherapy in this setting lacks a standardized approach. PATIENTS AND METHODS: Patients 16-30 weeks pregnant with locally advanced/metastatic disease or with high risk of recurrence after surgery were evaluated. RESULTS: Twenty patients received weekly epirubicin 35 mg/m(2). Median maternal age was 37 years (23-42). Median gestational age at chemotherapy was 19 weeks. Thirteen patients were treated after surgery while 7 had locally advanced tumours of which one had liver metastases...
June 2009: Breast Cancer Research and Treatment
A Sánchez Andrés, B Insa Albert, J I Carrasco Moreno, A Cano Sánchez, A Moya Bonora, J M Sáez Palacios
INTRODUCTION: Primary cardiac tumours are very rare in the paediatric age, their incidence varies from 0.0017 % to 0.28 %. More than 90 % are benign in nature. The most common variety is the rhabdomyoma, present in over 60 % of cases with tuberous sclerosis. MATERIAL AND METHODS: We performed a retrospective analysis of medical records with a diagnosis of primary cardiac tumor between March 1977 and March 2007, finding a total of 27 patients. RESULTS: The age of initial diagnosis is more prevalent in the neonatal period, beginning with the discovery of a heart murmur (11 cases)...
July 2008: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
J C Fouron
Foetal cardiology is a well established field of paediatric cardiology. It is no longer a simple exercise of prenatal diagnosis of cardiac malformations. It also covers the investigation and treatment of arrhythmias and functional and dynamic cardiocirculatory evaluation of the foetus which does not always have primary organic cardiac disease. It is this aspect which will be described in this article. The interactions of the left heart / foetal haemodynamics are classified in two main groups according to whether the left myocardial dysfunction is primary or secondary to changes of pre- or afterload...
May 2006: Archives des Maladies du Coeur et des Vaisseaux
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