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https://www.readbyqxmd.com/read/29454565/investigation-of-the-biomechanical-and-histopathological-effects-of-autologous-conditioned-serum-on-healing-of-achilles-tendon
#1
Erdinç Genç, Ozan Beytemur, Serdar Yuksel, Yılmaz Eren, Aysel Çağlar, Bedri Onur Küçükyıldırım, Mehmet Akif Güleç
OBJECTIVE: The aim of this study to evaluate the effects of autologous conditioned serum (ACS) on the healing of transected rat Achilles tendons via the assessment of biomechanical and histological parameters. METHODS: The study was conducted on 45 male Sprague-Dawley rats. Five rats were used as donors for ACS preparation. Animals were randomly assigned to the experimental or control group. In both groups, the Achilles tendon was cut transversally and then sutured...
February 14, 2018: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/29453583/reconstruction-for-chronic-achilles-tendinopathy-comparison-of-flexor-hallucis-longus-fhl-transfer-versus-v-y-advancement
#2
Jackson R Staggers, Kenneth Smith, Cesar de C Netto, Sameer Naranje, Krishna Prasad, Ashish Shah
BACKGROUND: Several operative techniques exist for Achilles tendinopathy. The purpose of our study was to compare the clinical and functional outcomes of flexor hallucis longus (FHL) transfer and V-Y advancement for the treatment of chronic insertional Achilles tendinopathy. METHODS: Retrospective chart review from 2010 to 2016 of patients that underwent FHL transfer or V-Y advancement for chronic insertional Achilles tendinopathy. Outcome measures were compared for these two procedures...
February 16, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29452899/influence-of-dominant-as-compared-with-nondominant-side-symptoms-on-disabilities-of-the-arm-shoulder-and-hand-and-western-ontario-rotator-cuff-scores-in-patients-with-rotator-cuff-tendinopathy
#3
David Høyrup Christiansen, Lori Michener, Jean-Sébastien Roy
HYPOTHESIS AND BACKGROUND: The Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire and the Western Ontario Rotator Cuff (WORC) index are 2 widely used patient-reported questionnaires in individuals with rotator cuff (RC) tendinopathy. In contrast to the WORC index, for which the items are specific to the affected shoulder, the items of the DASH questionnaire assess the ability to perform activities regardless of the arm used. The objective of this study is to determine whether scores on the DASH questionnaire and WORC index are affected if the symptoms are on the dominant or nondominant side in individuals with RC tendinopathy...
February 13, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29447933/ultrasound-guided-percutaneous-electrolysis-a-new-therapeutic-option-for-mammary-fistulas
#4
Juan D Berná-Serna, José A García-Vidal, Pilar Escolar-Reina, Juan D Berná-Mestre
Mammary fistula (MF) is a recurrent condition characterised by the draining of abscesses around the areola. The best management for MF remains challenging. Moreover, the main problem is the high recurrence rate of this disease. MF is considered a chronic process. The percutaneous electrolysis (PE) technique involves the application of a galvanic current with an ultrasound-guided needle to induce ablation and repair of the affected tissue. Good results have been obtained with PE in chronic tendinopathies. Below we present a hypothesis that PE may be a new therapeutic option for MF...
March 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29447021/release-of-pro-inflammatory-cytokines-from-muscle-and-bone-causes-tenocyte-death-in-a-novel-rotator-cuff-in-vitro-explant-culture-model
#5
Brianne K Connizzo, Alan J Grodzinsky
Tendinopathy is a significant clinical problem thought to be associated with altered mechanical loading. Explant culture models allow researchers to alter mechanical loading in a controlled in vitro environment while maintaining tenocytes in their native matrix. However, current models do not accurately represent commonly injured tendons, ignoring contributions of associated musculature and bone, as well as regional collagen structure. This study details the characterization of a mouse rotator cuff explant culture model, including bone, tendon, and muscle (BTM)...
February 15, 2018: Connective Tissue Research
https://www.readbyqxmd.com/read/29447016/tgf-b1-or-hypoxia-enhance-glucose-metabolism-and-lactate-production-via-hif1a-signaling-in-tendon-cells
#6
Katie J Sikes, Jun Li, Shu-Guang Gao, Quan Shen, John D Sandy, Anna Plaas, Vincent M Wang
Healthy tendons are maintained in homeostasis through controlled usage of glucose for energy and redox equilibrium. Tendon cell stress imposed by overuse injury or vascular insufficiency is accompanied by activation of wound healing pathways which facilitate an adaptive response and the restoration of homeostasis. To understand this response at the gene expression level we have studied the in vivo effects of injected TGF-β1 in a murine model of tendinopathy, as well as treatment of murine tendon explants with either TGF-β1 or hypoxia in vitro...
February 15, 2018: Connective Tissue Research
https://www.readbyqxmd.com/read/29444754/clinical-rating-systems-in-elbow-research-a-systematic-review-exploring-trends-and-distributions-of-use
#7
REVIEW
Jonathan P Evans, Chris D Smith, Nicola F Fine, Ian Porter, Jaheeda Gangannagaripalli, Victoria A Goodwin, Jose M Valderas
BACKGROUND: Clinical rating systems are used as outcome measures in clinical trials and attempt to gauge the patient's view of his or her own health. The choice of clinical rating system should be supported by its performance against established quality standards. METHODS: A search strategy was developed to identify all studies that reported the use of clinical rating systems in the elbow literature. The strategy was run from inception in Medline Embase and CINHAL...
February 12, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29438431/novel-animal-model-for-achilles-tendinopathy-controlled-experimental-study-of-serial-injections-of-collagenase-in-rabbits
#8
Cesar de Cesar Netto, Alexandre Leme Godoy-Santos, Pedro Augusto Pontin, Renato Jose Mendonça Natalino, Cesar Augusto Martins Pereira, Francisco Diego de Oliveira Lima, Lucas Furtado da Fonseca, Jackson Rucker Staggers, Leonardo Muntada Cavinatto, Lew Charles Schon, Olavo Pires de Camargo, Túlio Diniz Fernandes
Our goal was to develop a novel technique for inducing Achilles tendinopathy in animal models which more accurately represents the progressive histological and biomechanical characteristic of chronic Achilles tendinopathy in humans. In this animal research study, forty-five rabbits were randomly assigned to three groups and given bilateral Achilles injections. Low dose (LD group) (n = 18) underwent a novel technique with three low-dose (0.1mg) injections of collagenase that were separated by two weeks, the high dose group (HD) (n = 18) underwent traditional single high-dose (0...
2018: PloS One
https://www.readbyqxmd.com/read/29436233/intratissue-percutaneous-electrolysis-vs-corticosteroid-infiltration-for-the-treatment-of-plantar-fasciosis
#9
Álvaro Iborra-Marcos, Juan José Ramos-Álvarez, Guillermo Rodriguez-Fabián, Federico Del Castillo-González, Antonio López-Román, Carlos Polo-Portes, Manuel Villanueva-Martínez
BACKGROUND: Corticosteroid infiltration (CI) is commonly used for treatment of plantar fasciosis. In recent years, however, interest has grown in the use of intratissue percutaneous electrolysis (EPI) for the treatment of tendinopathies. The aim of our study was to compare the effectiveness of the above techniques in the treatment of plantar fasciosis. METHODS: The results achieved over a period of 1 year following the use of these techniques to treat plantar fasciosis were examined...
February 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29428875/ultrasound-guided-percutaneous-needle-tenotomy-for-chronic-proximal-tensor-fascia-lata-tendinopathy-a-report-of-2-cases
#10
David M Bradberry, Walter I Sussman, Kenneth Mautner
Proximal tensor fascia lata (TFL) tendinopathy at its origin on the anterior superior iliac crest is one potential cause of lateral hip pain. However, there is limited literature regarding the mechanism, disease course or management of this condition. There is growing evidence supporting the effective treatment of percutaneous needle tenotomy (PNT) for chronic tendinopathy. Only a single case series has examined the efficacy of PNT for tendinopathy about the hip and pelvis. Presented here are examples of two cases of chronic recalcitrant proximal ultrasound confirmed TFL tendinopathy effectively treated with ultrasound-guided PNT...
February 8, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29427310/psychological-factors-not-strength-deficits-are-associated-with-severity-of-gluteal-tendinopathy-a-cross-sectional-study
#11
M L Plinsinga, B K Coombes, R Mellor, P Nicolson, A Grimaldi, P Hodges, K Bennell, B Vicenzino
BACKGROUND: Gluteal tendinopathy is the most common lower limb tendinopathy presenting to general practice. It has a high prevalence among middle-aged females and impacts on daily activities, work participation and quality of life. The aim was to compare physical and psychological characteristics between subgroups of severity of pain and disability. METHODS: A multi-centre cross-sectional cohort of 204 participants (mean age 55 years, 82% female) who had a clinical diagnosis of gluteal tendinopathy with MRI confirmation were assessed...
February 9, 2018: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29417635/magnetic-resonance-imaging-following-regional-limb-perfusion-of-gadolinium-contrast-medium-in-26-horses
#12
S Aarsvold, M Solano, J Garcia-Lopez
BACKGROUND: Systemic administration of gadolinium contrast medium is common in small animals to increase lesion conspicuity and determine vascularisation of lesions identified with magnetic resonance imaging (MRI); however, the large volume required for systemic administration limits its use in equine patients. OBJECTIVES: The purpose of this study was to assess the feasibility of administering a low dose of contrast medium via venous regional limb perfusion. STUDY DESIGN: Prospective clinical study...
February 8, 2018: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29416964/arthroscopic-rotator-cuff-repair-with-mini-open-subpectoral-biceps-tenodesis
#13
Nicholas I Kennedy, George Sanchez, Sandeep Mannava, Márcio B Ferrari, Salvatore J Frangiamore, Matthew T Provencher
With a range of tear characteristics such as chronicity, degree of fatty atrophy, and number of tendons involved as well as varying patient-specific characteristics including age, injury mechanism, and expectations after treatment to consider, proper and successful treatment of a rotator cuff tear is multifactorial and, consequently, challenging. Although conservative management of a rotator cuff tear may be successful, a more severe tear with involvement of more tendons may warrant surgical intervention. Furthermore, additional pathology including biceps tendinopathy may result in greater patient morbidity and an even more complex treatment decision-making process and surgical technique...
October 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29409286/percutaneous-soft-tissue-release-performed-using-a-blunt-cannula-in-rabbits-with-chronic-collagenase-induced-achilles-tendinopathy
#14
Yueh-Ling Hsieh, Ming-Ta Lin, Chang-Zern Hong, Hsin-Shui Chen
BACKGROUND: This study investigated the effects of percutaneous soft tissue release (PSTR) performed using a blunt cannula on (1) the inflammatory cells-count, (2) expressions of calcitonin gene-related peptide (CGRP) and (3) substance P (SP) in rabbits with chronic phase of collagenase-induced Achilles tendinopathy. METHODS: Thirty-two adult male New Zealand rabbits were randomly divided into four groups: (1) collagenase and PSTR treatment; (2) collagenase and sham-operated PSTR treatment; (3) vehicle-only injection and PSTR treatment; and (4) vehicle-only injection and sham-operated PSTR treatment...
October 29, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29409246/prospective-study-of-the-inside-out-arthroscopic-ankle-ligament-technique-preliminary-result
#15
Caio Nery, Lucas Fonseca, Fernando Raduan, Marcus Moreno, Daniel Baumfeld
BACKGROUND: Lateral ankle ligament injury is among the most common orthopedic injuries. The objective of this study is to present the preliminary prospective results of treatment using the "Inside-Out" variant of the fully arthroscopic Broström-Gould technique. METHODS: Twenty six patients were included: 20 male and 6 female, aged 19-60 years, mean 41 years. All patients had positive "anterior drawer" and "talar tilt" tests. When necessary, cartilage injuries were treated with microfracture and arthroscopic resection for anterior impingement; three patients had hindfoot varus, on whom Dwyer osteotomy was performed; one patient had peroneal tendinopathy and was treated with tendoscopic debridement and another one had partial injury of the deltoid ligament, which was treated by direct repair...
March 22, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29409219/-%C3%A2-diagnostic-and-therapeutic-injections-of-the-foot-and-ankle-an-overview
#16
REVIEW
Cesar de Cesar Netto, Lucas Furtado da Fonseca, Felipe Simeone Nascimento, Andres Eduardo O'Daley, Eric W Tan, Eric J Dein, Alexandre Leme Godoy-Santos, Lew Charles Schon
Foot and ankle injections are useful diagnostic and therapeutic tools, particularly when the pain etiology is uncertain. A variety of foot and ankle injuries and pathologies, including degenerative joint disease, plantar fasciitis and different tendinopathies are amenable to injections. Understanding the foot and ankle anatomical landmarks, a thorough physical exam and knowledge of the different injection techniques is key for a successful approach to different pathologies. The objective of this study is to review the use of foot and ankle injections in the orthopaedic literature, present the readers with the senior author's experience and provide a comprehensive clinical guideline to the most common foot and ankle diagnostic and therapeutic injections...
February 14, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29409190/clinical-presentation-and-surgical-management-of-chronic-achilles-tendon-disorders-a-retrospective-observation-on-a-set-of-consecutive-patients-being-operated-by-the-same-orthopedic-surgeon
#17
Håkan Alfredson, Christoph Spang
BACKGROUND: Non-invasive treatment is not always successful in patients with Achilles tendon disorders, and surgical treatment is instituted as the next step. There is sparse knowledge about the diagnoses, pain levels before surgery, surgically confirmed pathologies and postoperative complications in large patient groups. AIMS: To study the diagnoses, pain scores before surgery, macroscopic surgical findings and postoperative complications in a series of patients treated for Achilles disorders...
June 12, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29399753/sonography-in-the-instability-of-the-long-head-of-the-biceps-tendon-confronted-with-histopathologic-and-arthroscopic-findings
#18
Jan Zabrzyński, Łukasz Paczesny, Agnieszka Zabrzyńska, Dariusz Grzanka, Łukasz Łapaj
Disorders of the long head of the biceps tendon (LHBT) are a common source of shoulder pain and disability. This tendon can be well visualized using ultrasonography; however, little is known if such examination allows clinicians to predict pathological changes of the tendon structure. In the study described below, we compare preoperative sonographic findings with the data from shoulder arthroscopy and microscopic examination of the excised tendon fragments in 19 consecutive patients with LHB tendinopathy and clinical suspicion of its instability...
February 5, 2018: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/29399446/mini-open-subpectoral-biceps-tenodesis-using-a-suture-anchor
#19
Christopher Arena, Aman Dhawan
The long head of the biceps (LHB) tendon is a potential source of shoulder pain encountered by orthopaedic surgeons. A multitude of approaches to addressing LHB tendinopathy have been described. These include various surgical techniques such as tenodesis versus tenotomy, an arthroscopic versus an open approach, and differing methods of tenodesis fixation. Our preferred approach to addressing LHB tendinopathy is through a mini-open approach using a double-loaded 4.5-mm suture anchor. This Technical Note with accompanying video describes our technique for performing this procedure, as well as supporting clinical evidence and technical pearls...
October 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29395632/predictors-of-clinical-success-in-runners-with-patellofemoral-pain-secondary-analyses-of-a-randomized-clinical-trial
#20
Jean-Francois Esculier, Laurent J Bouyer, Blaise Dubois, Jean Leblond, Mélanie Brisson, Luc Chau, Jean-Sébastien Roy
OBJECTIVES: To identify predictors of outcome to a rehabilitation program focused on education and management of training loads in runners with patellofemoral pain (PFP). DESIGN: Secondary analyses of a randomized clinical trial. METHODS: Fifty-eight runners with PFP (62% female, aged 31.2±6.6years, running 20.3±5.6km/week) were included in analyses. Following baseline collection of demographics, anthropometry, symptomatology, isometric strength, running mechanics and radiological data, runners were randomized to one of the three 8-week intervention program: (1) Education on symptoms management and training modifications; (2) Education+Exercise program; (3) Education+Gait retraining...
January 27, 2018: Journal of Science and Medicine in Sport
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