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https://www.readbyqxmd.com/read/28231627/factors-predicting-recovery-from-suicide-in-attempted-suicide-patients
#1
Fan-Ko Sun, Chu-Yun Lu, Yun Shan Tseng, Chun-Ying Chiang
AIMS AND OBJECTIVES: The aim of this study was to explore the factors predicting suicide recovery and to provide guidance for healthcare professionals when caring for individuals who have attempted suicide. BACKGROUND: The high rate of suicide is a global health problem. Suicide prevention has become an important issue in contemporary mental health. Most suicide research has focused on suicidal prevention and care. There is a lack of research on the factors predicting suicidal recovery DESIGN: A cross-sectional design was adopted...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231604/variations-in-body-morphology-explain-gender-differences-in-thermoeffector-function-during-compensable-heat-stress
#2
Sean R Notley, Joonhee Park, Kyoko Tagami, Norikazu Ohnishi, Nigel A S Taylor
Gender is sometimes thought to independently modulate cutaneous vasomotor and sudomotor function during heat exposure. Nevertheless, it was hypothesised that, when assessed during compensable exercise that evoked equal heat-loss requirements across participants, gender differences in those thermoeffectors would be explained by variations in the ratio between body surface area and mass (specific surface area). To evaluate that possibility, vasomotor and sudomotor functions were assessed in sixty individuals (36 males, 24 females) with widely varying (overlapping) specific surface areas (range: 232...
February 23, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28231557/comparison-of-body-s-center-of-mass-motion-relative-to-center-of-pressure-between-treadmill-and-over-ground-walking
#3
Hsuan-Lun Lu, Tung-Wu Lu, Hsiu-Chen Lin, Wing P Chan
Treadmills have been used in rehabilitation settings to provide convenient protocols and continuous monitoring of movement over multiple cycles at well-controlled speeds for gait and balance training. However, the potential differences in the movement control may affect the translation of the training outcomes to real life over-ground walking (OW). The similarities and differences in the balance control between treadmill walking (TW) and OW have largely been unexplored. The current study bridged the gap by comparing the motions of the body's center of mass (COM) relative to the center of pressure (COP) between TW and OW, in terms of the COM-COP inclination angle (IA) and its rate of change (RCIA)...
February 9, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28231528/identification-of-uv-absorbing-extractables-from-rubber-closures-used-in-containers-of-injectable-powder-and-safety-assessment-of-leachables-in-the-drug
#4
Yulei Wei, Ying Wu, Tingli Zhu, Zhiyan Li, Yilan Zhang
Rubber closures have been of great concern to regulatory authorities on account of their potential safety risks to patients. The aim of our work is to provide part of data about the compatibility of the injectable powder and its packaging materials for the drug registration. In this report, methodologies were established to study the system of the preparation. Firstly, three major extractables were isolated by semi-preparative HPLC method combined with silica gel-based chromatographic methods. NMR spectra including 1D NMR ((1)H, (13)C, DEPT135) and 2D NMR (COSY, HSQC, HMBC) were introduced to identify the extractables, besides HPLC, GC-MS, ESI-MS/MS and HRMS...
February 16, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28231439/the-rights-of-drug-treatment-patients-experience-of-addiction-treatment-in-poland-from-a-human-rights-perspective
#5
Justyna Klingemann
BACKGROUND: Drug dependence is a recognized medical condition and therefore, right to health applies in the same way to drug dependence as it does to any other health condition. The human rights in patient care framework - which refers to the application of basic human rights principles in the delivery of health care services - was used to explore the experiences of equality in the dignity and rights protected by Polish law within four different specialist drug treatment settings in Poland...
February 20, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28231400/evaluation-of-the-combined-use-of-narrow-band-imaging-and-high-speed-imaging-to-discriminate-laryngeal-lesions
#6
Veronika Volgger, Axelle Felicio, Jörg Lohscheller, Anna S Englhard, Hanan Al-Muzaini, Christian S Betz, Maria E Schuster
BACKGROUND AND OBJECTIVE: Laryngeal lesions are usually investigated by microlaryngoscopy, biopsy, and histopathology. This study aimed to evaluate the combined use of Narrow Band Imaging (NBI) and High-Speed Imaging (HSI) in the differentiation of glottic lesions in awake patients. STUDY DESIGN: Prospective diagnostic study. MATERIALS AND METHODS: Thirty-six awake patients with 41 glottic lesions were investigated with both NBI and HSI, and the suspected diagnoses were compared to the histopathological results of tissue biopsies taken during subsequent microlaryngoscopies...
February 23, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28231398/living-with-melanoma-%C3%A2-for-a-day-a-phenomenological-analysis-of-medical-students-simulated-experiences
#7
M Corr, G Roulston, N King, T Dornan, C Blease, G J Gormley
BACKGROUND: Despite the rising incidence of melanoma, medical students have progressively fewer opportunities to encounter patients with this important condition. Curricula tend to attach the greatest value to intellectual forms of learning. Compared to intellectual learning, however, experiential learning affords students deep insights about a condition. Doctors who experience ill health are more empathic towards patients. However opportunities to learn about cancer experientially are limited...
February 23, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28231337/4d-dose-simulation-in-volumetric-arc-therapy-accuracy-and-affecting-parameters
#8
Thilo Sothmann, Tobias Gauer, René Werner
Radiotherapy of lung and liver lesions has changed from normofractioned 3D-CRT to stereotactic treatment in a single or few fractions, often employing volumetric arc therapy (VMAT)-based techniques. Potential unintended interference of respiratory target motion and dynamically changing beam parameters during VMAT dose delivery motivates establishing 4D quality assurance (4D QA) procedures to assess appropriateness of generated VMAT treatment plans when taking into account patient-specific motion characteristics...
2017: PloS One
https://www.readbyqxmd.com/read/28231314/satisfaction-guaranteed-how-individual-partner-and-relationship-factors-impact-sexual-satisfaction-within-partnerships
#9
Julia Velten, Jürgen Margraf
Within committed relationships, a wide range of factors may challenge or facilitate sexual satisfaction. The aim of this study was to clarify which individual, partner-, and partnership-related aspects of a sexual relationship are crucial for the prediction of sexual satisfaction. The study included data of a representative sample of 964 couples from the general population. The actor-partner interdependence model was used to estimate actor and partner effects. Overall, predictors explained 57% of outcome variance...
2017: PloS One
https://www.readbyqxmd.com/read/28231309/improving-molecular-diagnosis-of-aniridia-and-wagr-syndrome-using-customized-targeted-array-based-cgh
#10
Fiona Blanco-Kelly, María Palomares, Elena Vallespín, Cristina Villaverde, Rubén Martín-Arenas, Camilo Vélez-Monsalve, Isabel Lorda-Sánchez, Julián Nevado, María José Trujillo-Tiebas, Pablo Lapunzina, Carmen Ayuso, Marta Corton
Chromosomal deletions at 11p13 are a frequent cause of congenital Aniridia, a rare pan-ocular genetic disease, and of WAGR syndrome, accounting up to 30% of cases. First-tier genetic testing for newborn with aniridia, to detect 11p13 rearrangements, includes Multiplex Ligation-dependent Probe Amplification (MLPA) and karyotyping. However, neither of these approaches allow obtaining a complete picture of the high complexity of chromosomal deletions and breakpoints in aniridia. Here, we report the development and validation of a customized targeted array-based comparative genomic hybridization, so called WAGR-array, for comprehensive high-resolution analysis of CNV in the WAGR locus...
2017: PloS One
https://www.readbyqxmd.com/read/28231247/favipiravir-pharmacokinetics-in-ebola-infected-patients-of-the-jiki-trial-reveals-concentrations-lower-than-targeted
#11
Thi Huyen Tram Nguyen, Jérémie Guedj, Xavier Anglaret, Cédric Laouénan, Vincent Madelain, Anne-Marie Taburet, Sylvain Baize, Daouda Sissoko, Boris Pastorino, Anne Rodallec, Géraldine Piorkowski, Sara Carazo, Mamoudou N Conde, Jean-Luc Gala, Joseph Akoi Bore, Caroline Carbonnelle, Frédéric Jacquot, Hervé Raoul, Denis Malvy, Xavier de Lamballerie, France Mentré
BACKGROUND: In 2014-2015, we assessed favipiravir tolerance and efficacy in patients with Ebola virus (EBOV) disease (EVD) in Guinea (JIKI trial). Because the drug had never been used before for this indication and that high concentrations of the drugs were needed to achieve antiviral efficacy against EBOV, a pharmacokinetic model had been used to propose relevant dosing regimen. Here we report the favipiravir plasma concentrations that were achieved in participants in the JIKI trial and put them in perspective with the model-based targeted concentrations...
February 23, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28231149/microalgae-nutraceuticals
#12
REVIEW
Marcello Nicoletti
Among the new entries in the food supplements sector, an important place must be assigned to nutraceuticals containing microalgae, nowadays accounting for a large and rapidly expanding market. The marketed products are mainly based on three production strains, i.e., Spirulina and Chlorella, followed at a distance by Klamath. It is a composite situation, since two of them are cyanobacteria and the second one is eukaryotic. The reality is that each presents similarities in shape and appearance concerning the marketed form and several utilizations, and peculiarities that need special attention and adequate studies...
August 22, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28231087/reducing-postharvest-losses-during-storage-of-grain-crops-to-strengthen-food-security-in-developing-countries
#13
REVIEW
Deepak Kumar, Prasanta Kalita
While fulfilling the food demand of an increasing population remains a major global concern, more than one-third of food is lost or wasted in postharvest operations. Reducing the postharvest losses, especially in developing countries, could be a sustainable solution to increase food availability, reduce pressure on natural resources, eliminate hunger and improve farmers' livelihoods. Cereal grains are the basis of staple food in most of the developing nations, and account for the maximum postharvest losses on a calorific basis among all agricultural commodities...
January 15, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28231086/a-theoretical-analysis-for-assessing-the-variability-of-secondary-model-thermal-inactivation-kinetic-parameters
#14
Maria C Giannakourou, Nikolaos G Stoforos
Traditionally, for the determination of the kinetic parameters of thermal inactivation of a heat labile substance, an appropriate index is selected and its change is measured over time at a series of constant temperatures. The rate of this change is described through an appropriate primary model and a secondary model is applied to assess the impact of temperature. By this approach, the confidence intervals of the estimates of the rate constants are not taken into account. Consequently, the calculated variability of the secondary model parameters can be significantly lower than the actual variability...
January 12, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28231066/valuing-environmental-health-for-informed-policy-making
#15
Vojtěch Máca, Jan Melichar, Milan Ščasný, Markéta Braun Kohlová
BACKGROUND: Monetized environmental health impact assessments help to better evaluate the environmental burden of a wide range of economic activities. Apart from the limitations and uncertainties in physical and biological science used in such assessments, assumptions taken from economic valuation may also substantially influence subsequent policy-making considerations. AIM: This study attempts to demonstrate the impact of normative policy assumptions on quantified external costs using a case study of recently discussed variants of future coal mining and use of extracted coal in electricity and heat generation in the Czech Republic...
February 23, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/28231056/temporal-and-regional-variability-in-the-request-of-vitamin-d-from-general-practitioners-in-spain
#16
Maria Salinas, Maite López-Garrigós, Emilio Flores, Carlos Leiva-Salinas
BACKGROUND: Our main goal is to study the inter-practice regional variability and the temporal evolution in the request of 25-hydroxyvitamin D (25[OH]D) by general practitioners (GPs) in Spain. METHODS: Clinical laboratories in different autonomic communities (AACCs) were invited to report the number of 25(OH)D test requested by GPs during 2012 and 2014. The number of 25(OH)D requested per 1000 inhabitants and the index of variability were calculated, and compared between regions and time periods...
February 23, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28231023/increasing-nocardia-incidence-associated-with-bronchiectasis-at-a-tertiary-care-center
#17
Michael H Woodworth, Jennifer L Saullo, Paul M Lantos, Gary M Cox, Jason E Stout
RATIONALE: Nocardia is a genus of pathogens that most commonly afflicts immunocompromised hosts, but may be an emerging infection among persons with bronchiectasis. OBJECTIVES: To examine the epidemiology and clinical presentation of adult patients with Nocardia and bronchiectasis relative to other patient groups. METHODS: We examined a retrospectively-assembled cohort of adults at Duke University Hospital in Durham, North Carolina with at least one positive culture from a bodily fluid or tissue specimen for Nocardia between January 1996 and December 2013...
February 23, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28230909/a-general-instrumental-variable-framework-for-regression-analysis-with-outcome-missing-not-at-random
#18
Eric J Tchetgen Tchetgen, Kathleen E Wirth
The instrumental variable (IV) design is a well-known approach for unbiased evaluation of causal effects in the presence of unobserved confounding. In this article, we study the IV approach to account for selection bias in regression analysis with outcome missing not at random. In such a setting, a valid IV is a variable which (i) predicts the nonresponse process, and (ii) is independent of the outcome in the underlying population. We show that under the additional assumption (iii) that the IV is independent of the magnitude of selection bias due to nonresponse, the population regression in view is nonparametrically identified...
February 23, 2017: Biometrics
https://www.readbyqxmd.com/read/28230899/shared-care-across-the-interface-between-primary-and-specialty-care-in-management-of-long-term-conditions
#19
REVIEW
Susan M Smith, Gráinne Cousins, Barbara Clyne, Shane Allwright, Tom O'Dowd
BACKGROUND: Shared care has been used in the management of many chronic conditions with the assumption that it delivers better care than primary or specialty care alone; however, little is known about the effectiveness of shared care. OBJECTIVES: To determine the effectiveness of shared care health service interventions designed to improve the management of chronic disease across the primary/specialty care interface. This is an update of a previously published review...
February 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28230893/the-effect-of-body-mass-on-outdoor-adult-human-decomposition
#20
Lindsey G Roberts, Jessica R Spencer, Gretchen R Dabbs
Forensic taphonomy explores factors impacting human decomposition. This study investigated the effect of body mass on the rate and pattern of adult human decomposition. Nine males and three females aged 49-95 years ranging in mass from 73 to 159 kg who were donated to the Complex for Forensic Anthropology Research between December 2012 and September 2015 were included in this study. Kelvin accumulated degree days (KADD) were used to assess the thermal energy required for subjects to reach several total body score (TBS) thresholds: early decomposition (TBS ≥6...
February 23, 2017: Journal of Forensic Sciences
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