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Endoscopic submucosal dissection

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https://www.readbyqxmd.com/read/28806821/endoscopic-submucosal-dissection-of-colitis-related-dysplasia
#1
Noriko Suzuki, Takashi Toyonaga, James E East
Background and study aims Endoscopic submucosal dissection (ESD) offers en bloc resection of lesions, allowing precise pathological assessment. Although possible in ulcerative colitis (UC) patients, the chronic inflammation may increase the procedural risks and reduce the complete resection rate. The aim of this study was to assess the feasibility of ESD for UC and to consider the factors contributing to its technical difficulty. Patients and methods Multicenter experiences of ESD for UC were retrospectively analyzed by reviewing endoscopic videos, pictures, reports, and clinical notes...
August 14, 2017: Endoscopy
https://www.readbyqxmd.com/read/28803459/prediction-of-esophageal-stricture-in-patients-administered-locoregional-triamcinolone-injections-immediately-after-endoscopic-submucosal-dissection
#2
Yasuaki Nagami, Masaki Ominami, Masatsugu Shiba, Taishi Sakai, Shusei Fukunaga, Satoshi Sugimori, Koji Otani, Shuhei Hosomi, Fumio Tanaka, Koichi Taira, Noriko Kamata, Hirokazu Yamagami, Tetsuya Tanigawa, Toshio Watanabe, Takuma Ishihara, Kouji Yamamoto, Yasuhiro Fujiwara
BACKGROUND AND AIM: Esophageal endoscopic submucosal dissection (ESD) to resect widespread lesions has increased the incidence of strictures, and some patients develop strictures despite receiving prophylactic locoregional triamcinolone injections. This study evaluated the predictive factors for esophageal stricture formation in patients administered prophylactic triamcinolone injections after ESD. METHODS: This was a retrospective observational study. Of 552 consecutive patients who underwent ESD, those who received prophylactic triamcinolone injections immediately after ESD were enrolled...
August 13, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28799258/helicobacter-pylori-infection-and-serum-level-of-pepsinogen-are-associated-with-the-risk-of-metachronous-gastric-neoplasm-after-endoscopic-resection
#3
Y Kwon, S Jeon, S Nam, I Shin
BACKGROUND: Patients who have undergone endoscopic resection of early gastric cancers (EGCs) are at risk for metachronous gastric neoplasm. AIM: To determine whether serum level of pepsinogen (PG), a marker of gastric atrophy, can determine which patients who have undergone endoscopic submucosal dissection for EGC are at risk for metachronous gastric neoplasm. We also investigated the effects of Helicobacter pylori eradication on metachronous gastric neoplasm incidence...
August 11, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28797987/continued-use-of-low-dose-aspirin-may-increase-risk-of-bleeding-after-gastrointestinal-endoscopic-submucosal-dissection-a-meta-analysis
#4
Wei Wu, Jingdi Chen, Qianshan Ding, Dongmei Yang, Honggang Yu, Jun Lin
BACKGROUND/AIMS: Endoscopic submucosal dissection has been widely accepted. At present, the number of antiplatelet (APT) users has been growing. Moreover, because of high risks of thromboembolism, some patients need to continuously receive APT agents. The relationship between hemorrhage and continuous therapy with low-dose aspirin (LDA) remains controversial. MATERIALS AND METHODS: A systematic search was conducted; studies were screened out- if data of no-anticoagulant/APT drugs use and interrupted and continued-LDA use were reported separately...
August 9, 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/28795364/survival-benefit-of-additional-surgery-after-non-curative-endoscopic-submucosal-dissection-for-early-gastric-cancer-a-propensity-score-matching-analysis
#5
Sho Suzuki, Takuji Gotoda, Waku Hatta, Tsuneo Oyama, Noboru Kawata, Akiko Takahashi, Yoshikazu Yoshifuku, Shu Hoteya, Masahiro Nakagawa, Masaaki Hirano, Mitsuru Esaki, Mitsuru Matsuda, Ken Ohnita, Kohei Yamanouchi, Motoyuki Yoshida, Osamu Dohi, Jun Takada, Keiko Tanaka, Shinya Yamada, Tsuyotoshi Tsuji, Hirotaka Ito, Yoshiaki Hayashi, Tooru Shimosegawa
BACKGROUND AND PURPOSE: Previous studies comparing survival outcomes between patients who did and did not undergo additional surgery after non-curative endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) were limited in that the baseline characteristics differed significantly between the groups. We aimed to address this limitation and compared survival outcomes between these two groups using propensity score matching analysis. METHODS: The study enrolled 1969 consecutive patients who underwent non-curative ESD for EGC between 2000 and 2011 at any of 19 institutions across Japan...
August 9, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28791503/endoscopic-submucosal-dissection-for-esophagogastric-junction-tumors-a-single-center-experience
#6
Joong Keun Kim, Gwang Ha Kim, Bong Eun Lee, Chul Hong Park, Hye Kyung Jeon, Dong Hoon Baek, Geun Am Song
BACKGROUND: Surgical resection for esophagogastric junction (EGJ) tumors is more aggressive and worsens the quality of life of the patients and leads to poor prognosis even after surgery compared with tumors in other sites of the stomach. Endoscopic submucosal dissection (ESD) is a widely accepted treatment modality for premalignant lesions and early cancers in the stomach. However, EGJ tumor is one of the most technically difficult lesions to resect by ESD. Therefore, this study aimed to evaluate the therapeutic outcomes of ESD for EGJ epithelial neoplasms and to assess the predictive factors for incomplete resection...
August 8, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28791322/efficacy-and-safety-of-endoscopic-submucosal-dissection-for-superficial-cancer-of-the-cervical-esophagus
#7
Toshiro Iizuka, Daisuke Kikuchi, Shu Hoteya, Yoshiaki Kajiyama, Mitsuru Kaise
BACKGROUND AND STUDY AIMS : Cervical esophageal cancer (CEC) is a less common form of cancer and often locally advanced at the time of diagnosis; thus, survival rates for patients with CEC remain poor. However, no reports exist on results of endoscopic submucosal dissection (ESD) for superficial cancer at the cervical esophagus. The aim of this retrospective study was to elucidate the clinicopathological features and clinical outcomes of ESD for superficial CEC. PATIENTS AND METHODS:  ESD was performed on 891 lesions (in 662 patients) for superficial esophageal cancer from January 2008 to December 2015...
August 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28791321/two-electrosurgical-endo-knives-for-endoscopic-submucosal-dissection-of-colorectal-superficial-neoplasms-a-prospective-randomized-study
#8
Yuusaku Sugihara, Keita Harada, Yoshiro Kawahara, Daisuke Takei, Shiho Takashima, Toshihiro Inokuchi, Asuka Nakarai, Masahiro Takahara, Kenji Kuwaki, Sakiko Hiraoka, Hiroyuki Okada
BACKGROUND AND STUDY AIMS : Few studies have directly compared endo-knives for endoscopic submucosal dissection (ESD) in humans. We compared the performances of the Mucosectom2 and SB knife Jr. PATIENTS AND METHODS:  Two trainee endoscopists performed ESD of 36 lesions in this prospective, randomized controlled trial. Mucosal incision with a 1.5-mm Dual knife and submucosal dissection using the Mucosectom2 were performed in 1 group. Mucosal incision with a 1...
August 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28783926/filling-the-technical-gap-between-standard-endoscopic-mucosal-resection-and-full-endoscopic-submucosal-dissection-for-20-35-mm-sized-colorectal-neoplasms
#9
https://www.readbyqxmd.com/read/28769979/safety-and-effectiveness-of-endoscopist-directed-nurse-administered-sedation-during-gastric-endoscopic-submucosal-dissection
#10
Yong Suk Cho, Sang Youn Shin, Changhyeok Hwang, Jeonghun Seo, Jong Won Choi, Byung Kyu Park, Sun Young Won, Chun Kyon Lee, Yong Kang Lee, Han Ho Jeon
BACKGROUND AND AIMS: Endoscopic submucosal dissection (ESD) is routinely performed in treating gastric neoplasia and requires long-term higher levels of sedation. Endoscopist-directed nurse-administered sedation (EDNAS) has not been well studied in ESD. This study aimed to evaluate the safety and effectiveness of EDNAS for ESD. METHODS: Patients treated with ESD for gastric tumors between 2013 and 2015 were retrospectively collected. Patients were divided into a midazolam-treated group (M group) and a midazolam plus propofol-treated group (MP group)...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28761366/colorectal-endoscopic-submucosal-dissection-patient-selection-and-special-considerations
#11
REVIEW
Andrew Emmanuel, Shraddha Gulati, Margaret Burt, Bu'Hussain Hayee, Amyn Haji
Endoscopic submucosal dissection (ESD) enables en bloc resection of large complex colorectal superficial neoplastic lesions, resulting in very low rates of local recurrence, high-quality pathologic specimens for accurate histopathologic diagnosis and potentially curative treatment of early adenocarcinoma without resorting to major surgical resection. The safety and efficacy of the technique, which was pioneered in the upper gastrointestinal tract, has been established by the consistently impressive outcomes from expert centers in Japan and some other eastern countries...
2017: Clinical and Experimental Gastroenterology
https://www.readbyqxmd.com/read/28759932/water-pressure-method-for-duodenal-endoscopic-submucosal-dissection
#12
Naohisa Yahagi, Toshihiro Nishizawa, Motoki Sasaki, Yasutoshi Ochiai, Toshio Uraoka
No abstract text is available yet for this article.
July 31, 2017: Endoscopy
https://www.readbyqxmd.com/read/28759148/efficacy-of-prednisone-for-prevention-of-esophageal-stricture-after-endoscopic-submucosal-dissection-for-superficial-esophageal-squamous-cell-carcinoma
#13
Gaosu Zhou, Fangfang Yuan, Jizhen Cai, Xiaowei Tang, Wei Gong, Lei Su, Yali Zhang
BACKGROUND: Our objective was to investigate the efficacy and safety of oral prednisone for the prevention of esophageal stricture formation after endoscopic submucosal dissection (ESD) in an optimal administration program. METHODS: Patients who underwent circumferential or semi-circumferential (more than three quarters but not a complete circular) ESD for esophageal squamous cell carcinoma were eligible for this study. Oral prednisolone was administered to the study group at a dose of 30 mg/day on the third day post-ESD, and then tapered gradually (30, 25, 20, 15, 10, and 5 mg for 14 days)...
July 31, 2017: Thoracic Cancer
https://www.readbyqxmd.com/read/28757866/efficacy-safety-and-overall-quality-of-life-of-endoscopic-submucosal-dissection-for-early-colorectal-cancer-in-elderly-patients
#14
Liang Liu, Xingjie Shen, Jingyu Zhu
PURPOSE: Studies reporting the treatment of early colorectal cancer (ECC) by endoscopic submucosal dissection (ESD) in elderly patients are lacking in China. The aim was to evaluate the efficacy, safety and overall quality of life of elderly patients with ECC who undergoing ESD. METHODS: Three hundred and seventy-nine patients with 401 colorectal lesions entered into our study from March 2013 to March 2016 (Patients with an age 70 years old or older were divided into the elderly group and those who were less than 70-year-old entered the non-elderly group)...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28756652/iatrogenic-gastric-pseudolipomatosis-during-endoscopic-submucosal-dissection
#15
Sang Wook Kim, Woo Sung Moon
No abstract text is available yet for this article.
July 31, 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/28750769/comparison-of-endoscopic-therapies-for-rectal-carcinoid-tumors-endoscopic-mucosal-resection-with-circumferential-incision-versus-endoscopic-submucosal-dissection
#16
Jinyan Zhang, Ming Liu, Hua Li, Jinzhong Chen, Hong Su, Jianwei Zheng, Guanxia Lin, Xiaoyi Lei
BACKGROUND AND OBJECTIVE: Although various endoscopic resection techniques have been established for rectal carcinoid tumors, there remains controversy regarding the best endoscopic treatment modality for these tumors. This study aimed to evaluate and compare the therapeutic efficacy and safety of EMR with circumferential incision (EMR-CI) and endoscopic submucosal dissection (ESD) for endoscopic resection of rectal carcinoid tumors. METHODS: From March 2012 to June 2016, 66 rectal carcinoid tumors in 66 patients were resected by using EMR-CI (n=30) or ESD (n=36)...
July 24, 2017: Clinics and Research in Hepatology and Gastroenterology
https://www.readbyqxmd.com/read/28749205/esophageal-endoscopic-submucosal-dissection-using-sodium-hyaluronate-is-safe-and-effective
#17
Chihiro Iwashita, Hirotsugu Sakamoto, Yoshimasa Miura, Satoshi Shinozaki, Yoshikazu Hayashi, Yuji Ino, Hiroyuki Osawa, Mio Tamba, Kohei Morita, Alan Kawarai Lefor, Hironori Yamamoto
BACKGROUND/AIMS: A submucosal cushion of sodium hyaluronate facilitates gastric and colorectal endoscopic submucosal dissection (ESD). However, few studies have evaluated the utility of sodium hyaluronate for ESD of esophageal lesions. The aim of this study is to evaluate the utility and safety of sodium hyaluronate for ESD of superficial esophageal squamous cell neoplasms (ESCN). MATERIAL AND METHODS: We retrospectively reviewed 111 ESCN in 86 patients treated by ESD between September 2007 and April 2013...
July 27, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28748455/resection-of-rectal-cancer-resembling-submucosal-tumor-that-was-preoperatively-diagnosed-with-endoscopic-ultrasound-guided-biopsy
#18
Akimitsu Tanio, Hiroaki Saito, Keigo Ashida, Shouichi Urushibara, Manabu Yamamoto, Naruo Tokuyasu, Teruhisa Sakamoto, Soichiro Honjo, Yoshihiko Maeta, Yoshiyuki Fujiwara
BACKGROUND: Colorectal cancer (CRC) resembling submucosal tumor (SMT; CRC/SMT) is very rare. Because its biopsy is challenging, accurate preoperative diagnosis is also very rare. CASE PRESENTATION: A 55-year-old woman with a high serum carcinoembryonic antigen level underwent a computed tomography colonoscopy, which showed extrinsic rectum compression. A coronal magnetic resonance image showed a 4-cm low-intensity tumor between her rectum and sacrum. Endoscopic ultrasound (EUS) showed a 30-mm low-echoic lesion originating from the rectum...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28746176/comparison-of-clinical-outcomes-after-endoscopic-submucosal-dissection-and-surgery-in-the-treatment-of-early-gastric-cancer-a-single-institute-study
#19
COMPARATIVE STUDY
Ji Young Chang, Ki-Nam Shim, Chung Hyun Tae, Ko Eun Lee, Jihyun Lee, Kang Hoon Lee, Chang Mo Moon, Seong-Eun Kim, Hye-Kyung Jung, Sung-Ae Jung, Joo-Ho Lee, Min-Sun Cho
The feasibility of expanding the indications for endoscopic submucosal dissection to treat early gastric cancer based on long-term outcomes has shown conflicting results. This study aimed to investigate whether outcomes or adverse events associated with endoscopic submucosal dissection are comparable to those of surgery for early gastric cancer that including the absolute and expanded indications.Data of 159 early gastric cancers from 153 patients treated with endoscopic submucosal dissection or surgery between January 2004 and October 2014 were reviewed retrospectively...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28743145/endoscopic-submucosal-dissection-of-early-colorectal-neoplasms-with-a-monopolar-scissor-type-knife-short-to-long-term-outcomes
#20
Toshio Kuwai, Toshiki Yamaguchi, Hiroki Imagawa, Yuki Sumida, Takeshi Takasago, Yuki Miyasako, Tomoyuki Nishimura, Sumio Iio, Atsushi Yamaguchi, Hirotaka Kouno, Hiroshi Kohno, Sauid Ishaq
Background and study aims Endoscopic submucosal dissection (ESD) for colorectal neoplasms remains challenging because of technical issues imposed by the complex anatomical features of the large intestine. We evaluated the feasibility, and the short- and long-term clinical outcomes of ESD for early colorectal neoplasms performed using the Stag-beetle Knife Jr. (SB Knife Jr.) Patients and methods We retrospectively assessed 228 patients who underwent ESD for 247 colorectal lesions with the SB Knife Jr. Clinicopathological characteristics of the neoplasms, complications, and various short- and long-term outcomes were evaluated...
July 25, 2017: Endoscopy
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