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Endoscopic submucosal dissection

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https://www.readbyqxmd.com/read/28920152/sentinel-node-navigation-surgery-for-early-gastric-cancer-analysis-of-factors-which-affect-direction-of-lymphatic-drainage
#1
Atsuo Shida, Norio Mitsumori, Shuichi Fujioka, Yuta Takano, Muneharu Fujisaki, Ryosuke Hashizume, Naoto Takahashi, Yoshio Ishibashi, Katsuhiko Yanaga
BACKGROUND AND PURPOSE: We started performing sentinel node navigation surgery (SNNS) for patients with early gastric cancer (EGC) using infrared ray electronic endoscopy (IREE) with indocyanine green injection from year 2000. The EGCs usually have complex lymphatic drainage, unidirectional or multidirectional lymphatic flow. In this study, we investigated and clarified factors that affect the direction of gastric lymphatic drainage. PATIENTS AND METHOD: Consecutive 60 patients with EGC who underwent SNNS by IREE from year 2006 to 2014 were enrolled to this study...
September 18, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28917905/characterization-of-a-water-soluble-chitosan-derivative-and-its-potential-for-submucosal-injection-in-endoscopic-techniques
#2
Hidemi Hattori, Hironori Tsujimoto, Kazuo Hase, Masayuki Ishihara
To examine the potential of chitosan-based agents for submucosal injection in endoscopic techniques, a chitosan derivative was prepared with lactose moieties linked to the amino groups of its glucosamine units (CH-LA). After dissolving CH-LA in neutral pH solutions, including physiological saline (CH-LA-S), its response to different concentrations of anionic glycosaminoglycans and proteins in the surrounding environment was examined. The CH-LA-S form changed in the presence of sulfated glycosaminoglycans (heparin, chondroitin sulfate, and mucin) and protein (fibrinogen)...
November 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28917342/endoscopic-submucosal-dissection-in-endotherapy-for%C3%A2-barrett-s-esophagus-related-dysplasia-and-neoplasia-an%C3%A2-essential-or-optional-technique
#3
EDITORIAL
Prasad G Iyer
No abstract text is available yet for this article.
October 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28917341/endoscopic-submucosal-dissection-for-barrett-s-neoplasia-decade-of-experience-little-progress-is-esd-the-best-for-complex-barrett-s-neoplasia
#4
EDITORIAL
Hassan Siddiki, Norio Fukami
No abstract text is available yet for this article.
October 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28910851/efficacy-of-hemostatic-powder-in-preventing-bleeding-after-gastric-endoscopic-submucosal-dissection-in-high-risk-patients
#5
Kyu Yeon Hahn, Jun Chul Park, Yong Kang Lee, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee
BACKGROUND AND STUDY AIM: The prevention of post-endoscopic submucosal dissection (ESD) bleeding in high-risk patients is an important problem. This study evaluated the efficacy of polysaccharide hemostatic powder in preventing post-ESD bleeding in high-risk patients. METHODS: Patients at high risk for post-ESD bleeding were prospectively enrolled between December 2015 and July 2016. A high risk of post-ESD bleeding was considered if the patients were taking antithrombotic agents or had undergone a large resection (specimen size ≥ 40mm)...
September 14, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28905334/endoscopic-submucosal-dissection-for-a-heterotopic-gland-in-the-transverse-colon
#6
Sayo Ito, Kinichi Hotta, Kenichiro Imai, Tadakazu Shimoda, Hiroyuki Ono
No abstract text is available yet for this article.
September 13, 2017: Endoscopy
https://www.readbyqxmd.com/read/28904301/a-case-of-gastric-lipoma-resected-by-endoscopic-submucosa-dissection-with-difficulty-in-preoperative-diagnosis
#7
Mizue Ichinose, Takuto Hikichi, Yukiko Kanno, Naohiko Gunji, Masashi Fujita, Masahito Kuroda, Kumiko Terashima, Yoshinori Sato, Satoshi Kawana, Yuko Hashimoto, Hiromasa Ohira, Masayuki Miyata
A 66-year-old man was referred to our hospital with an increasing subepithelial lesion in the gastric antrum. Using esophagogastroduodenoscopy, a tumor with a steep, 20-mm-high rise protruding in the lumen was observed. The mucosal surface of the tumor was reddish, with ulcers forming at the base. Moreover, the tumor was mobile and soft. A biopsy specimen was taken from the ulcer, but tumor tissue was not collected from the submucosa. Endoscopic ultrasonography (EUS) showed a high echoic mass in the submucosa...
September 14, 2017: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/28894466/clinical-factors-of-delayed-perforation-after-endoscopic-submucosal-dissection-for-gastric-neoplasms
#8
Yoshinobu Yamamoto, Hogara Nishisaki, Hideki Sakai, Nagahiro Tokuyama, Hiroaki Sawai, Aya Sakai, Takuya Mimura, Saeko Kushida, Hidetaka Tsumura, Takeshi Sakamoto, Ikuya Miki, Masahiro Tsuda, Hideto Inokuchi
BACKGROUND: Delayed perforation is a rare but severe complication of endoscopic submucosal dissection (ESD) for early gastric neoplasm (EGN). The aim of this study was to clarify clinical factors related to delayed perforation after ESD. METHODS: A total of 1158 consecutive patients with 1199 EGNs underwent ESD at our hospital between January 2000 and December 2015. Univariate analysis was used to identify clinicopathological factors related to delayed perforation...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28890117/potential-for-peritoneal-cancer-cell-seeding-in-endoscopic-full-thickness-resection-for-early-gastric-cancer
#9
Osamu Goto, Masayuki Shimoda, Motoki Sasaki, Yoshiyuki Kiguchi, Yutaka Mitsunaga, Teppei Akimoto, Yasutoshi Ochiai, Ai Fujimoto, Tadateru Maehata, Toshihiro Nishizawa, Hiroya Takeuchi, Yuko Kitagawa, Kaori Kameyama, Naohisa Yahagi
BACKGROUND AND AIMS: During endoscopic full-thickness resection (EFTR) for cancers, whether exposure of the lumen to the abdominal cavity during the procedure is acceptable is controversial because of the potential risk of tumor cell seeding. To assess the possibility of transplantation due to contact with tumor cells during the procedure, we prospectively investigated the ability of cancer cells to be detached by touching the tumor surface. METHODS: In 48 patients with a single early gastric cancer resected by endoscopic submucosal dissection, stamp cytology was performed by touching the surface of the specimens to glass slides...
September 7, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28885903/a-minimally-invasive-treatment-for-early-gi-cancers
#10
REVIEW
Lady Katherine Mejía-Pérez, Seiichiro Abe, Tyler Stevens, Mansour A Parsi, Sunguk N Jang, Ichiro Oda, John J Vargo, Yutaka Saito, Amit Bhatt
Endoscopic submucosal dissection (ESD) allows curative resection of early malignant gastrointestinal (GI) lesions, potentially avoiding open surgery. Unfortunately, awareness of this technique is low, and many patients undergo surgery without consideration of ESD. This article reviews the indications for ESD and its advantages and limitations, and guides internists in their approach to patients with early GI cancer.
September 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28885374/predictive-factors-to-diagnosis-undifferentiated-early-gastric-cancer-after-endoscopic-submucosal-dissection
#11
Dae G Ryu, Cheol W Choi, Dae H Kang, Hyung W Kim, Su B Park, Su J Kim, Hyeong S Nam
It is difficult to predict precisely whether the lesion corresponds to endoscopic resection indication. Furthermore, discrepancy may occur between endoscopic forceps biopsy (EFB) and finally resected specimen, which may be diagnosed as undifferentiated cancer and additional surgery may be required. Our study aimed to evaluate predictive factors to diagnose undifferentiated cancer after endoscopic submucosal dissection (ESD).Among the 532 patients diagnosed by ESD between January 2009 and December 2015, 557 early gastric cancer (EGC) cases were studied...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28885349/endoscopic-submucosal-dissection-for-large-colorectal-epithelial-neoplasms-a-single-center-experience-in-north-china
#12
Xin Xu, Tao Wang, Zhongqing Zheng, Xin Chen, Wentian Liu, Chao Sun, Bangmao Wang
Colorectal endoscopic submucosal dissection (ESD) is a technically difficult procedure with a higher risk of complications, especially for large colorectal epithelial neoplasms. This study aimed to report our experience and clinical outcomes, and to estimate the factors associated with incomplete resection and complications.One hundred forty one colorectal epithelial neoplasms in 130 consecutive patients treated by ESD at the endoscopy center of Tianjin Medical University General Hospital from January 2013 to January 2016 were included...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28885329/simultaneous-endoscopic-submucosal-dissection-for-multiple-early-gastric-cancers-in-a-low-volume-center
#13
Zhao-Sheng Chen, Xi-Feng Jin, Hong-Lei Wu, Jian-Qiang Guo
The aim of the study is to evaluate the safety and efficacy of simultaneous endoscopic submucosal dissection (ESD) for multiple early gastric cancers.A total of 70 solitary early gastric cancers from 70 patients and 20 multiple early gastric cancers from 10 patients were included in this retrospective study. The curative resection rate, en bloc resection rate, procedure-related complications, and local recurrence were compared between the 2 groups.There was no statistical difference in the rate of complete resection, en bloc resection, and curative resection between the 2 groups (P > ...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28884493/endoscopic-submucosal-dissection-in-the-west-current-status-and-future-directions
#14
REVIEW
Michael X Ma, Michael J Bourke
Endoscopic submucosal dissection (ESD) was first conceptually described almost 30 years ago in Japan and is now widely practiced throughout East Asia. ESD expands the boundaries of endoscopic resection (ER) by allowing en bloc resection of large early neoplastic lesions within the gastrointestinal tract (GIT). This offers advantages over other ER techniques by facilitating definitive histological staging and curative treatment of early cancer in selected cases. Indeed the experience of ESD in Eastern countries is significant, and excellent outcomes from high volume centres are reported...
September 7, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28881911/vascular-density-of-superficial-esophageal-squamous-cell-carcinoma-determined-by-direct-observation-of-resected-specimen-using-narrow-band-imaging-with-magnifying-endoscopy
#15
D Kikuchi, T Iizuka, S Hoteya, K Nomura, Y Kuribayashi, T Toba, M Tanaka, S Yamashita, T Furuhata, A Matsui, T Mitani, N Inoshita, M Kaise
Observation of the microvasculature using narrow band imaging (NBI) with magnifying endoscopy is useful for diagnosing superficial squamous cell carcinoma. Increased vascular density is indicative of cancer, but not many studies have reported differences between cancerous and noncancerous areas based on an objective comparison. We observed specimens of endoscopic submucosal dissection (ESD) using NBI magnification, and determined the vascular density of cancerous and noncancerous areas. A total of 25 lesions of esophageal squamous cell carcinoma that were dissected en bloc by ESD between July 2013 and December 2013 were subjected to NBI magnification...
November 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28881900/changes-in-esophageal-motility-after-endoscopic-submucosal-dissection-for-superficial-esophageal-cancer-a-high-resolution-manometry-study
#16
K Takahashi, Y Sato, M Takeuchi, H Sato, N Nakajima, S Ikarashi, K Hayashi, K-I Mizuno, Y Honda, S Hashimoto, J Yokoyama, S Terai
The effect of endoscopic submucosal dissection (ESD) on esophageal motility remains unknown. Therefore, the aim of this study is to elucidate changes in esophageal motility after ESD along with the cause of dysphagia using high-resolution manometry (HRM). This is a before-and-after trial of the effect of ESD on the esophageal motility. Twenty patients who underwent ESD for superficial esophageal carcinoma were enrolled in this study. Patients filled out a questionnaire about dysphagia and underwent HRM before and after ESD...
November 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28881899/polyglycolic-acid-sheet-and-fibrin-glue-for-preventing-esophageal-stricture-after-endoscopic-submucosal-dissection-a-historical-control-study
#17
T Iizuka, D Kikuchi, S Hoteya, Y Kajiyama, M Kaise
There have been several reports that steroid administration is effective at preventing strictures after endoscopic submucosal dissection (ESD). However, adverse events after steroid use are of great concern. We have reported that shielding with a polyglycolic acid (PGA) sheet and fibrin glue can be useful for prevention of stricture after ESD. We conducted a retrospective analysis of efficiency of shielding with a PGA sheet and fibrin glue for prevention of esophageal stricture compared with intralesional steroid injection...
November 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28881703/current-status-of-lymph-node-micrometastasis-in-gastric-cancer
#18
REVIEW
Yang Zhou, Guo-Jing Zhang, Ji Wang, Kai-Yuan Zheng, Weihua Fu
Lymph node metastasis is one of the most important prognostic factors in patients with gastric cancer. An inadequate number of dissected lymph nodes is an independent risk factor affecting recurrence, even in patients who are node negative. Oddly, certain early-stage patients still experience recurrence or metastasis within a short time, even if they have undergone standard radical mastectomy. Many researchers have attributed these adverse events to lymph node micrometastasis (LNM), which is defined as a microscopic deposit of malignant cells of less than 2 mm in diameter...
August 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28879570/preoperative-pulmonary-function-tests-predict-aspiration-pneumonia-after-gastric-endoscopic-submucosal-dissection
#19
Akihiro Matsumi, Ryuta Takenaka, Chihiro Ando, Yuki Sato, Kensuke Takei, Eriko Yasutomi, Shotaro Okanoue, Shohei Oka, Daisuke Kawai, Junro Kataoka, Koji Takemoto, Hirofumi Tsugeno, Shigeatsu Fujiki, Yoshiro Kawahara
BACKGROUND: ESD allows higher rates of en-bloc and R0 resections, but has occasionally complications such as aspiration pneumonia. Factors associated with aspiration pneumonia are not completely understood. AIMS: To analyze the relationship between aspiration pneumonia and preoperative factors including pulmonary function tests. METHODS: A total of 978 patients with gastric tumors who had received pulmonary function tests were treated by ESD between June 2006 and May 2014...
September 6, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28877814/limited-resection-of-the-duodenum-for-nonampullary-duodenal-tumors-with-review-of-the-literature
#20
REVIEW
Daisuke Hashimoto, Kota Arima, Akira Chikamoto, Katsunobu Taki, Risa Inoue, Takayoshi Kaida, Takaaki Higashi, Katsunori Imai, Toru Beppu, Hideo Baba
The surgical management of duodenal pathology is challenging because of its retroperitoneal position and shared blood supply with the pancreas. We present three types of limited resection of the duodenum for the removal of superficial or small nonampullary duodenal (NADL) lesions, and also a review of the English literature regarding management, such as endoscopic resection and limited duodenal resection. Ten cases underwent limited resections of the duodenum for superficial or small NADL lesions from 2011 to 2015...
November 1, 2016: American Surgeon
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