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Endoscopic submucosal dissection

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https://www.readbyqxmd.com/read/28078115/usefulness-and-feasibility-of-endoscopic-submucosal-dissection-for-colorectal-tumor-a-nationwide-multicenter-retrospective-study-in-korea
#1
Ji Hye Kim, Il Hyun Baek, Kyoung Oh Kim, Hyun Joo Jang, Gwang Ho Baik, Chang Kyun Lee, Kyeong Won Min
BACKGROUND: Detection rate of precursor lesion of colorectal cancer and early colon cancer have recently been rising because of increased screening endoscopy and increased incidence of colorectal cancer. Endoscopic submucosal dissection (ESD) technique has been reported to be useful in the treatment of such superficial lesions in colon. However, nationwide multicenter study for usefulness and feasibility of colorectal ESD is still limited. METHODS: From January 2009 to February 2014, colorectal ESD data performed at nationwide university hospitals were enrolled in retrospective design...
December 2016: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28070097/a-well-differentiated-early-gastric-cancer-in-a-patient-confirmed-negative-for-helicobacter-pylori
#2
Narihiro Shibukawa, Shuji Wakamatsu, Shohei Ouchi, Yuhei Wakahara, Nobuyuki Tatsumi, Akira Kaneko
A woman in her 70s was an outpatient at our hospital. Esophagogastroduodenoscopy revealed a slightly elevated lesion with erosion, 10mm in diameter, located at the greater curvature of the antrum. Helicobacter pylori testing yielded negative results, and there was no atrophy of the gastric mucosa. Biopsy revealed a well-differentiated tubular adenocarcinoma. Complete en bloc resection was performed via endoscopic submucosal dissection, in accordance with the current Japanese guidelines. The gastric adenocarcinoma of the fundic gland type and coexisting with a hyperplastic or fundic gland polyp was negative according to the histological examination...
2017: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/28068717/endoscopic-submucosal-dissection-a-medical-education-perspective
#3
Neel Sharma
No abstract text is available yet for this article.
January 2017: Endoscopy
https://www.readbyqxmd.com/read/28068703/tunnel-and-clip-endoscopic-submucosal-dissection-of-a-pharyngeal-superficial-squamous-cell-carcinoma-detected-with-narrow-band-imaging
#4
Jérémie Jacques, Jérôme Rivory, Vincent Lépilliez, Leslie Rinaldi, Jean-Christophe Saurin, Thierry Ponchon, Mathieu Pioche
No abstract text is available yet for this article.
February 2017: Endoscopy
https://www.readbyqxmd.com/read/28068694/feasibility-of-performing-esophageal-endoscopic-submucosal-dissection-using-master-and-slave-transluminal-endoscopic-robot
#5
Nobuyoshi Takeshita, Khek Yu Ho, Soo Jay Phee, Jennie Wong, Philip Wai Yan Chiu
No abstract text is available yet for this article.
February 2017: Endoscopy
https://www.readbyqxmd.com/read/28064398/prognostic-significance-of-hyperfibrinogenemia-in-patients-with-esophageal-squamous-cell-carcinoma
#6
Takashi Suzuki, Hideaki Shimada, Tatsuki Nanami, Yoko Oshima, Satoshi Yajima, Naohiro Washizawa, Hironori Kaneko
BACKGROUND: Preoperative hyperfibrinogenemia is associated with inflammatory mediators and a poor prognosis in several types of cancer. However, there is no published information on the monitoring of patients with preoperative hyperfibrinogenemia after surgery. The aim of the study reported here was to assess the clinicopathological and prognostic significance of plasma fibrinogen levels in patients with esophageal squamous cell carcinoma before and after surgical treatment. METHODS: Plasma fibrinogen levels were analyzed before surgical treatment (endoscopic submucosal dissection and surgery) in 82 patients with esophageal squamous cell carcinoma...
January 7, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28058023/laparoscopic-and-endoscopic-co-operative-surgery-for-non-ampullary-duodenal-tumors
#7
Daisuke Ichikawa, Shuhei Komatsu, Osamu Dohi, Yuji Naito, Toshiyuki Kosuga, Kazuhiro Kamada, Kazuma Okamoto, Yoshito Itoh, Eigo Otsuji
AIM: To assess the safety and feasibility of laparoscopic and endoscopic co-operative surgery (LECS) for early non-ampullary duodenal tumors. METHODS: Twelve patients with a non-ampullary duodenal tumor underwent LECS at our hospital. One patient had two mucosal lesions in the duodenum. The indication for this procedure was the presence of duodenal tumors with a low risk for lymph node metastasis. In particular, the tumors included small (less than 10 mm) submucosal tumors (SMT) and epithelial mucosal tumors, such as mucosal cancers or large mucosal adenomas with malignant suspicion...
December 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28052695/management-of-early-colonic-neoplasia-where-are-we-now-and-where-are-we-heading
#8
Gaius Longcroft-Wheaton, Pradeep Bhandari
There have been considerable advances in the endoscopic treatment of colorectal neoplasia. The development of endoscopic submucosal dissection and full thickness resection techniques is changing the way benign disease and early cancers are managed. This article reviews the evidence behind these new techniques and discusses where this field is likely to move in the future. Areas covered: A PubMed literature review of resection techniques for colonic neoplasia was performed. The clinical and cost effectiveness of endoscopic mucosal resection (EMR) is examined...
January 4, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28052288/frequent-presence-of-lymphovascular-invasion-in-small-rectal-neuroendocrine-tumors-on-immunohistochemical-analysis
#9
Yoshiyasu Kitagawa, Dai Ikebe, Takuto Suzuki, Taro Hara, Makiko Itami, Taketo Yamaguchi
Rectal neuroendocrine tumors (RNETs) have become common in recent years and are good candidates for endoscopic resection (ER). To achieve clear resection margins, more advanced techniques such as endoscopic submucosal dissection, endoscopic submucosal resection with a ligation device, and cap-assisted endoscopic mucosal resection are available for ER. After ER, lymphovascular invasion (LVI) is regarded as an important predictor of nodal metastasis. Previous studies have shown that small RNETs with LVI were uncommon (0-8...
2017: Digestion
https://www.readbyqxmd.com/read/28052275/endoscopic-submucosal-dissection-and-endoscopic-mucosal-resection-for-non-ampullary-superficial-duodenal-tumor
#10
Shu Hoteya, Tsukasa Furuhata, Toba Takahito, Yumiko Fukuma, Yugo Suzuki, Daisuke Kikuchi, Toshifumi Mitani, Akira Matsui, Satoshi Yamashita, Kosuke Nomura, Yasutaka Kuribayashi, Toshiro Iizuka, Mitsuru Kaise
BACKGROUND: Endoscopic submucosal resection (ESD) and endoscopic mucosal resection (EMR) are well established as curable and safety procedures for treating superficial tumors of the stomach, esophagus and colon. However, a majority of endoscopic resection strategies for non-ampullary superficial duodenal tumors (NASDTs) remains undefined. The aim of this study was to clarify which was the right method for NASDT treatment - EMR or ESD. SUMMARY: We analyzed 129 consecutive endoscopic resection (74 ESD and 55 EMR) procedures performed with NADSTs and divided the ESD group into 49 large ESD groups (more than 20 mm in diameter) and 25 small ESD groups (less than 20 mm in diameter)...
2017: Digestion
https://www.readbyqxmd.com/read/28050913/technological-review-on-endoscopic-submucosal-dissection-available-equipment-recent-developments-and-emerging-techniques
#11
Georgios Mavrogenis, Juergen Hochberger, Pierre Deprez, Morteza Shafazand, Dimitri Coumaros, Katsumi Yamamoto
Endoscopic submucosal dissection (ESD) is widely practiced in Japan and the Eastern World and is rapidly expanding in western countries for the management of early malignancies of the upper and lower gastrointestinal tube. In addition, novel therapeutic applications deriving from ESD have emerged including the treatment of achalasia, of submucosal tumors, of diverticula, of strictures and of reflux disease. An ESD procedure necessitates not only skills and specific training, but also familiarization with a vast spectrum of devices (endoscopes, high-frequency generators and their settings, endoknives, hoods, irrigation devices) and techniques (such as countertraction, artificial ulcer closure), that render the procedure faster, more efficient and safer...
January 4, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28050786/multicenter-prospective-study-on-the-safety-of-upper-gastrointestinal-endoscopic-procedures-in-antithrombotic-drug-users
#12
Yoshiyasu Kono, Minoru Matsubara, Tatsuya Toyokawa, Ryuta Takenaka, Seiyu Suzuki, Junichirou Nasu, Masao Yoshioka, Masahiro Nakagawa, Motowo Mizuno, Hiroyuki Sakae, Makoto Abe, Tatsuhiro Gotoda, Ko Miura, Hiromitsu Kanzaki, Masaya Iwamuro, Keisuke Hori, Takao Tsuzuki, Masahide Kita, Seiji Kawano, Yoshiro Kawahara, Hiroyuki Okada
BACKGROUND: The Japan Gastroenterological Endoscopy Society updated its guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment in July 2012. However, the safety of endoscopic procedures in antithrombotic drug users has not been fully investigated. AIMS: To evaluate the safety of upper gastrointestinal endoscopic procedures in antithrombotic drug users. METHODS: From September 2013 to September 2015, patients who were taking antithrombotic drugs and who underwent upper gastrointestinal endoscopic procedures were prospectively enrolled at five hospitals...
January 3, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28042389/clinical-problems-with-antithrombotic-therapy-for-endoscopic-submucosal-dissection-for-gastric-neoplasms
#13
REVIEW
Toshiyuki Yoshio, Tsutomu Nishida, Yoshito Hayashi, Hideki Iijima, Masahiko Tsujii, Junko Fujisaki, Tetsuo Takehara
Endoscopic submucosal dissection (ESD) is minimally invasive and thus has become a widely accepted treatment for gastric neoplasms, particularly for patients with comorbidities. Antithrombotic agents are used to prevent thrombotic events in patients with comorbidities such as cardio-cerebrovascular diseases and atrial fibrillation. With appropriate cessation, antithrombotic therapy does not increase delayed bleeding in low thrombosis-risk patients. However, high thrombosis-risk patients are often treated with combination therapy with antithrombotic agents and occasionally require the continuation of antithrombotic agents or heparin bridge therapy (HBT) in the perioperative period...
December 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28042239/oral-steroid-prophylaxis-is-effective-in-preventing-esophageal-strictures-after-large-endoscopic-resection
#14
Jean-Philippe Ratone, Erwan Bories, Fabrice Caillol, Christian Pesenti, Sebastien Godat, Flora Poizat, Chiara De Cassan, Marc Giovannini
BACKGROUND: Strictures are frequent complications of large endoscopic mucosal resections (EMR) and endoscopic submucosal dissections of the esophagus. Local or systemic steroid therapy has shown promise in the prevention of secondary stenosis. The aim of this study was to evaluate the safety and efficacy of systemic steroid therapy following endoscopic resection of at least hemi-circumferential esophageal mucosa. METHODS: This was a single-center retrospective study in a tertiary center...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28039646/learning-curve-and-clinical-outcome-of-gastric-endoscopic-submucosal-dissection-performed-by-trainee-operators
#15
Masao Yoshida, Naomi Kakushima, Keita Mori, Kimihiro Igarashi, Noboru Kawata, Masaki Tanaka, Kohei Takizawa, Sayo Ito, Kenichiro Imai, Kinichi Hotta, Hirotoshi Ishiwatari, Hiroyuki Matsubayashi, Hiroyuki Ono
BACKGROUND: Although endoscopic submucosal dissection (ESD) represents a significant progress in therapeutic endoscopy, little is known about how trainees attain its technical proficiency. The aims of this study were to evaluate the learning curve and clinical outcomes of gastric ESD performed by trainee endoscopists. METHODS: Between April 2009 and March 2014, 334 gastric ESD procedures were performed by seven trainees (42-50 consecutive cases per trainee). The learning curve for gastric ESD was evaluated using the cumulative sum (CUSUM) method...
December 30, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/28028382/fice-vs-narrow-band-imaging-for-in-vivo-histologic-diagnosis-of-polyps
#16
Cevher Akarsu, Nuri Alper Sahbaz, Ahmet Cem Dural, Mustafa Gokhan Unsal, Osman Kones, Ali Kocatas, Ilkay Halicioglu, Halil Alis
BACKGROUND AND OBJECTIVES: Gastrointestinal cancers are the most frequently occurring cancers worldwide. Diagnosis and removal of polyps during screening endoscopy decreases the prevalence of colon cancer and cancer-related mortality, and it is considered to be the gold standard in gastrointestinal system cancer prevention. Technological innovations in endoscopy have led to revolutionary developments in many areas. Flexible spectral imaging color enhancement (FICE) and narrow-band imaging (NBI) are forms of digital chromoendoscopy and enhance the endoscopic images without the need for a dye...
October 2016: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28018108/heparin-bridge-therapy-and-post-polypectomy-bleeding
#17
Toshiyuki Kubo, Kentaro Yamashita, Kei Onodera, Tomoya Iida, Yoshiaki Arimura, Masanori Nojima, Hiroshi Nakase
AIM: To identify risk factors for post-polypectomy bleeding (PPB), focusing on antithrombotic agents. METHODS: This was a case-control study based on medical records at a single center. PPB was defined as bleeding that occurred 6 h to 10 d after colonoscopic polypectomy and required endoscopic hemostasis. As risk factors for PPB, patient-related factors including anticoagulants, antiplatelets and heparin bridge therapy as well as polyp- and procedure-related factors were evaluated...
December 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28011512/double-endoscopic-intraluminal-operation-deilo-for-early-gastric-cancer-outcome-of-novel-procedure-for-endoscopic-submucosal-dissection
#18
Kyoichi Ogata, Mitsuhiro Yanai, Kengo Kuriyama, Masaki Suzuki, Toru Yanoma, Akiharu Kimura, Norimichi Kogure, Yoshitaka Toyomasu, Tetsuro Ohno, Erito Mochiki, Hiroyuki Kuwano
Endoscopic submucosal dissection (ESD) has been used to treat patients with early gastric cancer (EGC). Although several endoscopic devices have been developed to ensure easy and safe ESD, this technique still requires an experienced, highly skilled endoscopist, as it is performed through a single gastroscope, thus requiring one-handed surgical techniques. To overcome these limitations, many ESD procedures with counter-traction have been developed, such as the double scope, double channel scope, clip with line, magnetic anchor, percutaneous traction and external grasping forceps methods...
January 2017: Anticancer Research
https://www.readbyqxmd.com/read/28009738/lymph-node-metastasis-in-mucosal-gastric-cancer-reappraisal-of-expanded-indication-of-endoscopic-submucosal-dissection
#19
Seung-Young Oh, Kyung-Goo Lee, Yun-Suhk Suh, Min A Kim, Seong-Ho Kong, Hyuk-Joon Lee, Woo Ho Kim, Han-Kwang Yang
OBJECTIVE: To evaluate risk factors for lymph node (LN) metastasis in mucosal gastric cancer, particularly the effect of cellular differentiation, and implications for the indication of endoscopic submucosal dissection (ESD). SUMMARY BACKGROUND DATA: The indication of ESD has been expanded to undifferentiated-type (UD-type) gastric cancer despite risk of LN metastasis. METHODS: Patients who underwent radical gastrectomy for pT1a stage primary gastric adenocarcinoma between 2008 and 2012 were retrospectively analyzed...
January 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28008290/in-situ-gelation-properties-of-a-collagen-genipin-sol-with-a-potential-for-the-treatment-of-gastrointestinal-ulcers
#20
Takefumi Narita, Shunji Yunoki, Yoshimi Ohyabu, Naohisa Yahagi, Toshio Uraoka
We investigated the potential of collagen-genipin sols as biomaterials for treating artificial ulcers following endoscopic submucosal dissection. Collagen sol viscosity increased with condensation, allowing retention on tilted ulcers before gelation and resulting in collagen gel deposition on whole ulcers. The 1.44% collagen sols containing genipin as a crosslinker retained sol fluidity at 23°C for >20 min, facilitating endoscopic use. Collagen sols formed gel depositions on artificial ulcers in response to body temperature, and high temperature responsiveness of gelation because of increased neutral phosphate buffer concentration allowed for thick gel deposition on tilted ulcers...
2016: Medical Devices: Evidence and Research
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