keyword
https://read.qxmd.com/read/38459128/structure-of-the-human-kmn-complex-and-implications-for-regulation-of-its-assembly
#21
JOURNAL ARTICLE
Soumitra Polley, Tobias Raisch, Sabrina Ghetti, Marie Körner, Melina Terbeck, Frauke Gräter, Stefan Raunser, Camilo Aponte-Santamaría, Ingrid R Vetter, Andrea Musacchio
Biorientation of chromosomes during cell division is necessary for precise dispatching of a mother cell's chromosomes into its two daughters. Kinetochores, large layered structures built on specialized chromosome loci named centromeres, promote biorientation by binding and sensing spindle microtubules. One of the outer layer main components is a ten-subunit assembly comprising Knl1C, Mis12C and Ndc80C (KMN) subcomplexes. The KMN is highly elongated and docks on kinetochores and microtubules through interfaces at its opposite extremes...
March 8, 2024: Nature Structural & Molecular Biology
https://read.qxmd.com/read/38458561/safer-bars-a-cluster-randomized-effectiveness-evaluation-of-alcohol-related-sexual-violence-prevention-through-bar-staff-bystander-training
#22
JOURNAL ARTICLE
Kelly Cue Davis, Mary P Koss, Elise C Lopez, Karyn Roberts
BACKGROUND: Sexual assault is consistently associated with social contexts that support high levels of alcohol consumption such as alcohol-serving establishments (i.e., bars). The significant rates of alcohol-involved sexual assault among college students demonstrate the critical need for evidence-based efforts to reduce alcohol-involved sexual assault in this population. Although bystander approaches have demonstrated some promise for reducing alcohol-involved sexual assault, to date no published studies have examined the effectiveness of implementing bystander prevention approaches with bar staff...
March 6, 2024: Contemporary Clinical Trials
https://read.qxmd.com/read/38454733/ultra-short-term-forecasting-model-of-power-load-based-on-fusion-of-power-spectral-density-and-morlet-wavelet
#23
JOURNAL ARTICLE
Lihe Liang, Jinying Cui, Juanjuan Zhao, Yan Qiang, Juanjuan Zhao
An accurate ultra-short-term time series prediction of a power load is an important guarantee for power dispatching and the safe operation of power systems. Problems of the current ultra-short-term time series prediction algorithms include low prediction accuracy, difficulty capturing the local mutation features, poor stability, and others. From the perspective of series decomposition, a multi-scale sequence decomposition model (TFDNet) based on power spectral density and the Morlet wavelet transform is proposed that combines the multidimensional correlation feature fusion strategy in the time and frequency domains...
February 4, 2024: Mathematical Biosciences and Engineering: MBE
https://read.qxmd.com/read/38453763/fatal-police-shootings-of-victims-with-mental-health-crises-a-descriptive-analysis-of-data-from-the-2014-2015-national-violent-death-reporting-system
#24
JOURNAL ARTICLE
Harun Khan, Matthew Miller, Catherine Barber, Deborah Azrael
One in five fatal police shooting victims may have been experiencing a mental health crisis (MHC) at the time of their death [1]. We use data on fatal police shootings from the National Violent Death Reporting System (2014-2015) to (a) identify incidents where the victim is reported to have experienced an MHC at the time of their death, (b) describe the characteristics of these incidents, and (c) compare the characteristics of MHC to fatal police shootings where the victim was not experiencing an MHC at the time of their death...
March 7, 2024: Journal of Urban Health
https://read.qxmd.com/read/38453733/-physician-assisted-interhospital-transfer-an-analysis-from-schleswig-holstein
#25
JOURNAL ARTICLE
Andrea Köser, Christine Eimer, Maximilian Feth, Ulf Lorenzen, Stephan Seewald, Henrik Lehn, Michael Corzillius, Bjarne Schmalbach, Florian Reifferscheid
BACKGROUND: The need for interhospital transport (IHT) of intensive care patients is increasing due to changes in the hospital environment. Interhospital transports are challenging and require careful operational planning of personnel and rescue vehicles. OBJECTIVE: To investigate the need for IHT, an analysis was conducted in the service area of the emergency medical service central dispatch center (IRLS) in Schleswig-Holstein. MATERIAL AND METHODS: Emergency physician-assisted IHT were analyzed in the period from 01...
March 7, 2024: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://read.qxmd.com/read/38451835/surgical-management-of-perineal-groove
#26
JOURNAL ARTICLE
Kristen Bridges, Pratibha Vemulapalli, Patrick LeBlanc, Brian Gilchrist
Alberto Peña's contributions to our understanding of pediatric perineal surgery and anatomy make this the rarest of anomalies both discernable and reparable. We diagnosed, managed and operated on the 24 th ever reported case of pure perineal groove. We review here the embryology, workup and surgical management necessary to successfully dispatch this disabling defect. Perineal grooves are so rare that a discussion of them is not included in Peña's masterpiece, "Surgical Management of Anorectal Malformations...
March 4, 2024: Journal of the American College of Surgeons
https://read.qxmd.com/read/38448994/characteristics-and-critical-care-interventions-in-drowning-patients-treated-by-the-danish-air-ambulance-from-2016-to-2021-a-nationwide-registry-based-study-with-30-day-follow-up
#27
JOURNAL ARTICLE
Niklas Breindahl, Signe A Wolthers, Thea P Møller, Stig N F Blomberg, Jacob Steinmetz, Helle C Christensen
BACKGROUND: Improving oxygenation and ventilation in drowning patients early in the field is critical and may be lifesaving. The critical care interventions performed by physicians in drowning management are poorly described. The aim was to describe patient characteristics and critical care interventions with 30-day mortality as the primary outcome in drowning patients treated by the Danish Air Ambulance. METHODS: This retrospective cohort study with 30-day follow-up identified drowning patients treated by the Danish Air Ambulance from January 1, 2016, through December 31, 2021...
March 6, 2024: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://read.qxmd.com/read/38448812/perceptions-of-professional-challenges-by-emergency-medical-services-providers-a-qualitative-content-analysis-study
#28
JOURNAL ARTICLE
Afshin Khazaei, Ali Afshari, Mahnaz Khatiban, Seyed Reza Borzou, Khodayar Oshvandi, Majedeh Nabavian, Maryam Maddineshat
INTRODUCTION: Emergency medical services (EMS) providers encounter a variety of challenges due to the unpredictable, uncontrollable, and dynamic conditions in the pre-hospital field. This study explored the perceived professional challenges among EMS providers. MATERIALS AND METHODS: This study was conducted using a qualitative research approach and the method of content analysis. Eighteen EMS providers were purposively selected from EMS stations in Hamadan, Iran...
March 6, 2024: BMC Emergency Medicine
https://read.qxmd.com/read/38448540/data-driven-assisted-real-time-optimal-control-strategy-of-submerged-arc-furnace-via-intelligent-energy-terminals-considering-large-scale-renewable-energy-utilization
#29
JOURNAL ARTICLE
Bowen Zheng, Mingming Pan, Qixin Liu, Xu Xu, Chang Liu, Xuchen Wang, Wen Chu, Shiming Tian, Jindou Yuan, Yuting Xu, Zishang Xu, Yongjun Li
This study presents a data-driven assisted real-time optimization model which is an innovative approach to address the challenges posed by integrating Submerged Arc Furnace (SAF) systems with renewable energy sources, specifically photovoltaic (PV) and wind power, with modern intelligent energy terminals. Specifically, the proposed method is divided into two stages. The first stage is related to data-driven prediction for addressing local time-varying renewable energy and electricity market prices with predicted information, and the second stage uses an optimization model for real-time SAF dispatch...
March 7, 2024: Scientific Reports
https://read.qxmd.com/read/38445487/compression-only-or-standard-cardiopulmonary-resuscitation-for-trained-laypersons-in-out-of-hospital-cardiac-arrest-a-nationwide-randomized-trial-in-sweden
#30
JOURNAL ARTICLE
Gabriel Riva, Erik Boberg, Mattias Ringh, Martin Jonsson, Andreas Claesson, Anette Nord, Sten Rubertsson, Hans Blomberg, Per Nordberg, Sune Forsberg, Mårten Rosenqvist, Leif Svensson, Cecilia Andréll, Johan Herlitz, Jacob Hollenberg
BACKGROUND: The ongoing TANGO2 (Telephone Assisted CPR. AN evaluation of efficacy amonGst cOmpression only and standard CPR) trial is designed to evaluate whether compression-only cardiopulmonary resuscitation (CPR) by trained laypersons is noninferior to standard CPR in adult out-of-hospital cardiac arrest. This pilot study assesses feasibility, safety, and intermediate clinical outcomes as part of the larger TANGO2 survival trial. METHODS: Emergency medical dispatch calls of suspected out-of-hospital cardiac arrest were screened for inclusion at 18 dispatch centers in Sweden between January 1, 2017, and March 12, 2020...
March 6, 2024: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/38445118/small-bowel-obstruction-due-to-abdominal-cocoon-syndrome-in-post-covid-19-patients
#31
JOURNAL ARTICLE
Mohammad Aboelnaga, Mohamed S Elkadi, Islam E Abdelhady, Yomna H Elwan
BACKGROUND: Abdominal cocoon syndrome, also recognized as encapsulating peritoneal sclerosis, is an exceedingly rare medical condition characterized by an anomalous membranous envelopment of the small bowel. Despite its clinical rarity, the precise etiology and pathogenic mechanisms of this syndrome remain elusive. METHODS: This comprehensive discussion presents a case series encompassing six patients who sought medical attention in the Emergency Room, all sharing a common presentation: severe abdominal distension and persistent constipation...
February 2024: Curēus
https://read.qxmd.com/read/38444508/co-optimisation-of-wind-and-solar-energy-and-intermittency-for-renewable-generator-site-selection
#32
JOURNAL ARTICLE
Hao Wu, Samuel R West
Sites for the construction of wind and solar farms have typically been chosen to maximise total energy generation of an individual site, but rarely consider the intermittency of the renewable resource available at each location. As more renewable generation is added to electricity grids around the world, this intermittency is rapidly becoming a major factor constraining the volume of renewable generation that can be added cost-effectively, as additional fast-response storage or dispatchable generation must compensate for periods of low renewable generation...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38441422/current-trends-in-the-management-of-out-of-hospital-cardiac-arrest-ohca
#33
JOURNAL ARTICLE
Michal Plodr, Eva Chalusova
Sudden cardiac arrest remains a relevant problem with a significant number of deaths worldwide. Although survival rates have more than tripled over the last 20 years (4% in 2001 vs. 14% in 2020), survival rates with good neurological outcomes remain persistently low, representing a major socioeconomic problem. Every minute of delay from patient collapse to start cardiopulmonary resuscitation (CPR) and early defibrillation reduces the chance of survival by approximately 10-12%. Therefore, the time to treatment is a crucial factor in the prognosis of patients with out-of-hospital cardiac arrest (OHCA)...
March 4, 2024: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://read.qxmd.com/read/38435580/daily-natural-gas-load-prediction-method-based-on-apso-optimization-and-attention-bilstm
#34
JOURNAL ARTICLE
Xinjing Qi, Huan Wang, Yubo Ji, Yuan Li, Xuguang Luo, Rongshan Nie, Xiaoyu Liang
As the economy continues to develop and technology advances, there is an increasing societal need for an environmentally friendly ecosystem. Consequently, natural gas, known for its minimal greenhouse gas emissions, has been widely adopted as a clean energy alternative. The accurate prediction of short-term natural gas demand poses a significant challenge within this context, as precise forecasts have important implications for gas dispatch and pipeline safety. The incorporation of intelligent algorithms into prediction methodologies has resulted in notable progress in recent times...
2024: PeerJ. Computer Science
https://read.qxmd.com/read/38429656/characteristics-of-the-most-severely-ill-and-injured-patients-in-a-norwegian-helicopter-emergency-medical-service-a-retrospective-cohort-study
#35
JOURNAL ARTICLE
Eirik Ringen, Helge Haugland, Jostein Rødseth Brede
BACKGROUND: Physician-staffed helicopter emergency medical services (HEMS) are dispatched to a variety of incidents, ranging from less serious to life-threatening. The skillset of a physician may be important to provide appropriate care for the most critically ill and severely injured patients. A better understanding of these patients may therefore be important to optimize dispatch criteria, training, and equipment setups for HEMS units. The aim of this study was to describe the characteristics of patients with the national advisory committee on aeronautics (NACA) score 5 and 6, primarily by diagnostic group and interventions performed...
March 2, 2024: BMC Emergency Medicine
https://read.qxmd.com/read/38422686/police-mental-health-co-response-versus-police-as-usual-response-to-behavioral-health-emergencies-a-pragmatic-randomized-effectiveness-trial
#36
JOURNAL ARTICLE
Evan Marie Lowder, Eric Grommon, Katie Bailey, Bradley Ray
BACKGROUND: People with mental illness are overrepresented in United States (US) criminal legal systems. In response, alternatives to traditional police response to behavioral health emergencies have become more common, despite limited evidence for their effectiveness. We conducted the first randomized controlled trial of a police-mental health co-response team to determine program effectiveness relative to a police-as-usual response on key outcomes identified by community stakeholders...
February 24, 2024: Social Science & Medicine
https://read.qxmd.com/read/38422061/evaluation-of-the-environmental-polio-surveillance-system-northern-region-ghana-2021
#37
JOURNAL ARTICLE
Benjamin Baguune, Eunice Baiden Laryea, Joseph Asamoah Frimpong, Samuel Dapaa, Kwame Kodom Achempem, Ernest Kenu, Dennis Odai Laryea
BACKGROUND: Acute Flaccid Paralysis (AFP) surveillance is the gold standard in the polio eradication initiative. The environmental component of polio surveillance can detect circulating Polioviruses from sewage without relying on clinical presentation. The effectiveness of the Environmental Surveillance (ES) is crucial to global polio eradication. We assessed the usefulness and attributes of the ES system in the Northern region and determined if the system is meeting its objectives. METHODS: We conducted a descriptive cross-sectional evaluation in the Northern region from 2019 to 2020 using the updated US Centers for Disease Control and Prevention guideline...
2024: PloS One
https://read.qxmd.com/read/38419263/the-impact-of-extreme-heat-on-older-regional-and-rural-australians-a-systematic-review
#38
REVIEW
Grace Harvey, Suzanne Bain-Donohue, Sari Puspa Dewi
INTRODUCTION: Extreme heat causes a major health burden, especially for older Australians. OBJECTIVE: To assess the impact of extreme heat on older regional and rural Australians, including clinical presentations, social implications, and health-seeking behaviours and adaptations. DESIGN: A systematic review and narrative synthesis. FINDINGS: Ten articles were included in the review with research on this topic limited...
February 28, 2024: Australian Journal of Rural Health
https://read.qxmd.com/read/38415406/overcrowding-in-the-dispatching-centre-during-the-covid-19-crisis-are-medical-students-a-resource
#39
JOURNAL ARTICLE
Delphine Douillet, Delphine Plard, François Morin, Yannick Courjault, Gwladys Gaultier, Nicolas Lerolle, François Templier, Pierre-Marie Roy, Dominique Savary
INTRODUCTION: In February, the emergence of COronaVIrus Disease 2019 (COVID - 19) in France made it necessary to rapidly adapt emergency and SAMU services in order to take care of many infected patients. To respond to the increase in the number of calls in the dispatch centers, reinforcements were necessary on the fronts of the Medical Regulation Assistants (ARM). The aim of this study was to assess the relevance of medical students' responses to first calls exclusively concerning COVID-19...
February 28, 2024: Disaster Medicine and Public Health Preparedness
https://read.qxmd.com/read/38415353/prehospital-point-of-care-ultrasound-in-ruptured-abdominal-aortic-aneurysms-a-retrospective-cohort-study
#40
JOURNAL ARTICLE
Signe Voigt Lauridsen, Morten Thingemann Bøtker, Nikolaj Eldrup, Peter Juhl-Olsen
BACKGROUND: Patients with ruptured abdominal aortic aneurysm (rAAA) require immediate vascular treatment to survive. The use of prehospital point-of-care ultrasound (POCUS) may support clinical assessment, correct diagnosis, appropriate triage and reduce system delay. The aim was to study the process of care and outcome in patients receiving prehospital POCUS versus patients not receiving prehospital POCUS in patients with rAAA, ruptured iliac aneurysm or impending aortic rupture. METHODS: We performed a retrospective cohort study in patients diagnosed with rAAA in the Central Denmark Region treated by a prehospital critical care physician from 1 January 2017 to 31 December 2021...
February 28, 2024: Acta Anaesthesiologica Scandinavica
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