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Quantitative radiology

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https://www.readbyqxmd.com/read/29155639/when-machines-think-radiology-s-next-frontier
#1
Keith J Dreyer, J Raymond Geis
Artificial intelligence (AI), machine learning, and deep learning are terms now seen frequently, all of which refer to computer algorithms that change as they are exposed to more data. Many of these algorithms are surprisingly good at recognizing objects in images. The combination of large amounts of machine-consumable digital data, increased and cheaper computing power, and increasingly sophisticated statistical models combine to enable machines to find patterns in data in ways that are not only cost-effective but also potentially beyond humans' abilities...
December 2017: Radiology
https://www.readbyqxmd.com/read/29152563/integrated-radiomic-framework-for-breast-cancer-and-tumor-biology-using-advanced-machine-learning-and-multiparametric-mri
#2
Vishwa S Parekh, Michael A Jacobs
Radiomics deals with the high throughput extraction of quantitative textural information from radiological images that not visually perceivable by radiologists. However, the biological correlation between radiomic features and different tissues of interest has not been established. To that end, we present the radiomic feature mapping framework to generate radiomic MRI texture image representations called the radiomic feature maps (RFM) and correlate the RFMs with quantitative texture values, breast tissue biology using quantitative MRI and classify benign from malignant tumors...
2017: NPJ Breast Cancer
https://www.readbyqxmd.com/read/29144159/shear-wave-elastography-quantitative-assessment-of-the-male-breast-added-value-to-distinguish-benign-and-malignant-palpable-masses
#3
Amandine Crombe, Gabrielle Hurtevent-Labrot, Maryam Asad-Syed, Jean Palussiere, Gaetan MacGrogan, Michèle Kind, Stéphane Ferron
OBJECTIVE: To evaluate the ability of shear-wave elastography (SWE) to distinguish between benign and malignant palpable masses of the adult male breast. METHODS: Clinical examination, mammography, B-mode and Doppler ultrasound (US) findings and SWE quantitative parameters were compared in 50 benign lesions (including 40 gynecomastias) and 15 malignant lesions (invasive ductal carcinomas) from 65 patients who were consecutively addressed for specialized advice at our comprehensive cancer center...
November 16, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29143222/quantitative-analysis-of-the-level-of-readability-of-online-emergency-radiology-based-patient-education-resources
#4
David R Hansberry, Michael D'Angelo, Michael D White, Arpan V Prabhu, Mougnyan Cox, Nitin Agarwal, Sandeep Deshmukh
PURPOSE: The vast amount of information found on the internet, combined with its accessibility, makes it a widely utilized resource for Americans to find information pertaining to medical information. The field of radiology is no exception. In this paper, we assess the readability level of websites pertaining specifically to emergency radiology. METHODS: Using Google, 23 terms were searched, and the top 10 results were recorded. Each link was evaluated for its readability level using a set of ten reputable readability scales...
November 15, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/29132999/radiologists-and-social-media-do-not-forget-about-facebook
#5
Rebecca L Seidel, Aryan Jalilvand, Jean Kunjummen, Lea Gilliland, Richard Duszak
PURPOSE: Facebook (Facebook, Inc, Menlo Park, California, USA) is the most popular social networking platform worldwide. Facebook groups are virtual communities of people who share a common interest. Breast Imaging Radiologists is a Facebook group for radiologists with an interest in breast imaging. The purpose of this study was to analyze the membership and activity of the Breast Imaging Radiologists Facebook group (BIRFG) for 2 years since its inception. METHODS: Using both the Grytics (www...
November 11, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29118170/lyta-quantitative-pcr-on-sputum-and-nasopharyngeal-swab-samples-in-the-detection-of-pneumococcal-pneumonia-among-the-elderly
#6
Annika Saukkoriipi, Arto A Palmu, Thierry Pascal, Vincent Verlant, William P Hausdorff, Jukka Jokinen
Quantitative real-time PCR (qPCR) on sputum or nasopharyngeal specimens has shown promising results in the detection of pneumococcal community-acquired pneumonia (PncCAP). We applied qPCR for the autolysin gene (lytA) and compared sputum and nasopharyngeal swab (NPS) pneumococcal loads in elderly patients with community-acquired pneumonia (CAP), and specifically in patients with PncCAP, to those in patient groups with other respiratory disease. We studied patients aged ≥65 years with radiologically confirmed CAP, clinical CAP not retrospectively radiologically confirmed, other acute respiratory infection, or stable chronic lung disease...
November 8, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29097316/quantitative-surface-analysis-of-combined-mri-and-pet-enhances-detection-of-focal-cortical-dysplasias
#7
Yee-Leng Tan, Hosung Kim, Seunghyun Lee, Tarik Tihan, Lawrence Ver Hoef, Susanne G Mueller, Anthony James Barkovich, Duan Xu, Robert Knowlton
OBJECTIVE: Focal cortical dysplasias (FCDs) often cause pharmacoresistant epilepsy, and surgical resection can lead to seizure-freedom. Magnetic resonance imaging (MRI) and positron emission tomography (PET) play complementary roles in FCD identification/localization; nevertheless, many FCDs are small or subtle, and difficult to find on routine radiological inspection. We aimed to automatically detect subtle or visually-unidentifiable FCDs by building a classifier based on an optimized cortical surface sampling of combined MRI and PET features...
October 31, 2017: NeuroImage
https://www.readbyqxmd.com/read/29092948/dcmqi-an-open-source-library-for-standardized-communication-of-quantitative-image-analysis-results-using-dicom
#8
Christian Herz, Jean-Christophe Fillion-Robin, Michael Onken, Jörg Riesmeier, Andras Lasso, Csaba Pinter, Gabor Fichtinger, Steve Pieper, David Clunie, Ron Kikinis, Andriy Fedorov
Quantitative analysis of clinical image data is an active area of research that holds promise for precision medicine, early assessment of treatment response, and objective characterization of the disease. Interoperability, data sharing, and the ability to mine the resulting data are of increasing importance, given the explosive growth in the number of quantitative analysis methods being proposed. The Digital Imaging and Communications in Medicine (DICOM) standard is widely adopted for image and metadata in radiology...
November 1, 2017: Cancer Research
https://www.readbyqxmd.com/read/29092816/dysregulation-of-both-mir-140-3p-and-mir-140-5p-in-synovial-fluid-correlate-with-osteoarthritis-severity
#9
C-M Yin, W-C-W Suen, S Lin, X-M Wu, G Li, X-H Pan
OBJECTIVES: This study looked to analyse the expression levels of microRNA-140-3p and microRNA-140-5p in synovial fluid, and their correlations to the severity of disease regarding knee osteoarthritis (OA). METHODS: Knee joint synovial fluid samples were collected from 45 patients with OA of the knee (15 mild, 15 moderate and 15 severe), ten healthy volunteers, ten patients with gouty arthritis, and ten with rheumatoid arthritis. The Kellgren-Lawrence grading (KLG) was used to assess the radiological severity of knee OA, and the patients were stratified into mild (KLG < 2), moderate (KLG = 2), and severe (KLG > 2)...
November 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/29091003/american-college-of-radiology-compliant-short-protocol-breast-mri-for-high-risk-breast-cancer-screening-a-prospective-feasibility-study
#10
Basak E Dogan, Marion E Scoggins, Jong Bum Son, Wei Wei, Rosalind Candelaria, Wei T Yang, Jingfei Ma
OBJECTIVE: The purpose of this study was to assess the feasibility of a short protocol for screening breast MRI that is noninferior to standard-of-care (SOC) MRI in image quality that complies with American College of Radiology accreditation requirements. SUBJECTS AND METHODS: In a prospective feasibility trial, 23 women at high risk underwent both an initial SOC MRI examination that included axial iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) and T1-weighted volume imaging for breast assessment (VIBRANT) dynamic contrast-enhanced sequences and a separate short breast MRI protocol comprising a fast spin-echo (FSE) triple-echo Dixon T2 sequence for T2-weighted imaging and a 3D dual-echo fast spoiled gradient-echo two-point Dixon sequence for dynamic contrast-enhanced imaging from October 1, 2015, through May 2, 2016...
November 1, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29090500/five-minute-knee-mri-for-simultaneous-morphometry-and-t2-relaxometry-of-cartilage-and-meniscus-and-for-semiquantitative-radiological-assessment-using-double-echo-in-steady-state-at-3t
#11
Akshay S Chaudhari, Marianne S Black, Susanne Eijgenraam, Wolfgang Wirth, Susanne Maschek, Bragi Sveinsson, Felix Eckstein, Edwin H G Oei, Garry E Gold, Brian A Hargreaves
BACKGROUND: Biomarkers for assessing osteoarthritis activity necessitate multiple MRI sequences with long acquisition times. PURPOSE: To perform 5-minute simultaneous morphometry (thickness/volume measurements) and T2 relaxometry of both cartilage and meniscus, and semiquantitative MRI Osteoarthritis Knee Scoring (MOAKS). STUDY TYPE: Prospective. SUBJECTS: Fifteen healthy volunteers for morphometry and T2 measurements, and 15 patients (five each Kellgren-Lawrence grades 0/2/3) for MOAKS assessment...
November 1, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29089821/selection-and-reporting-of-statistical-methods-to-assess-reliability-of-a-diagnostic-test-conformity-to-recommended-methods-in-a-peer-reviewed-journal
#12
Ji Eun Park, Kyunghwa Han, Yu Sub Sung, Mi Sun Chung, Hyun Jung Koo, Hee Mang Yoon, Young Jun Choi, Seung Soo Lee, Kyung Won Kim, Youngbin Shin, Suah An, Hyo-Min Cho, Seong Ho Park
OBJECTIVE: To evaluate the frequency and adequacy of statistical analyses in a general radiology journal when reporting a reliability analysis for a diagnostic test. MATERIALS AND METHODS: Sixty-three studies of diagnostic test accuracy (DTA) and 36 studies reporting reliability analyses published in the Korean Journal of Radiology between 2012 and 2016 were analyzed. Studies were judged using the methodological guidelines of the Radiological Society of North America-Quantitative Imaging Biomarkers Alliance (RSNA-QIBA), and COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) initiative...
November 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/29084064/new-insights-into-cerebral-small-vessel-disease-and-vascular-cognitive-impairment-from-mri
#13
Eric E Smith, Andrew E Beaudin
PURPOSE OF REVIEW: We review recent MRI research that addresses two important challenges in cerebral small vessel disease (SVD) research: early diagnosis, and linking SVD with cognitive impairment. First, we review studies of MRI measurements of blood flow and blood-brain barrier integrity. Second, we review MRI studies identifying neuroimaging correlates of SVD-related cognitive dysfunction, focusing on brain connectivity and white matter microarchitecture. This research is placed in context through discussion of recent recommendations for management of incidentally discovered SVD, and neuroimaging biomarker use in clinical trials...
October 27, 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29081020/a-model-of-fracture-risk-used-to-examine-the-link-between-bone-mineral-density-and-the-impact-of-different-therapeutic-mechanisms-on-fracture-outcomes-in-patients-with-osteoporosis
#14
Rena J Eudy-Byrne, William Gillespie, Matthew M Riggs, Marc R Gastonguay
A hazard model of fracture was developed using individual patient data (IPD) from the NHANES (2005-2008) database and summary-level data from an aggregate dataset (AD). The AD was built by performing a comprehensive and systematic literature search of clinical studies published from 1995 to 2015, recording fracture rate and bone mineral density (BMD) for both treatment and placebo arms. The search resulted in a metadata set comprised of 21 studies investigating the effects of various bisphosphonates, teriparatide, denosumab, and raloxifene in 65,254 patients over a cumulative 56...
October 28, 2017: Journal of Pharmacokinetics and Pharmacodynamics
https://www.readbyqxmd.com/read/29074467/vertebral-body-spread-in-thoracolumbar-burst-fractures-can-predict-posterior-construct-failure
#15
Federico De Iure, Giorgio Lofrese, Pasquale De Bonis, Michele Cappuccio, Francesco Cultrera, Sofia Battisti
BACKGROUND CONTEXT: The Load Sharing Classification (LSC) laid foundations for a scoring system able to indicate which thoracolumbar fractures, after short-segment posterior-only fixations, would need for longer instrumentations or additional anterior supports. PURPOSE: We analyzed surgically treated thoracolumbar fractures, quantifying the vertebral body's fragments displacement with the aim of identifying a new parameter which could predict the posterior-only construct failure...
October 23, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29063052/quantitative-magnetic-resonance-imaging-biomarkers-in-oncological-clinical-trials-current-techniques-and-standardization-challenges
#16
REVIEW
Jie Deng, Yi Wang
Radiological imaging plays an important role in oncological trials to provide imaging biomarkers for disease staging, stratifying patients, defining dose setting, and evaluating the safety and efficacy of new candidate drugs and innovative treatment. This paper reviews the techniques of most commonly used quantitative magnetic resonance imaging (qMRI) biomarkers (dynamic contrast enhanced, dynamic susceptibility contrast, and diffusion weighted imaging) and their applications in oncological trials. Challenges of incorporating qMRI biomarkers in oncological trials are discussed including understanding biological mechanisms revealed by MRI biomarkers, consideration of rigorous trial design and standardized implementation of qMRI protocols...
March 25, 2017: Chronic Dis Transl Med
https://www.readbyqxmd.com/read/29057899/breast-lesion-characterization-using-textural-features-of-quantitative-ultrasound-parametric-maps
#17
Ali Sadeghi-Naini, Harini Suraweera, William Tyler Tran, Farnoosh Hadizad, Giancarlo Bruni, Rashin Fallah Rastegar, Belinda Curpen, Gregory J Czarnota
This study evaluated, for the first time, the efficacy of quantitative ultrasound (QUS) spectral parametric maps in conjunction with texture-analysis techniques to differentiate non-invasively benign versus malignant breast lesions. Ultrasound B-mode images and radiofrequency data were acquired from 78 patients with suspicious breast lesions. QUS spectral-analysis techniques were performed on radiofrequency data to generate parametric maps of mid-band fit, spectral slope, spectral intercept, spacing among scatterers, average scatterer diameter, and average acoustic concentration...
October 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29055617/qualitative-and-quantitative-radiological-analysis-of-non-contrast-ct-is-a-strong-indicator-in-patients-with-acute-pyelonephritis
#18
Fadi El-Merhi, May Mohamad, Ali Haydar, Lena Naffa, Rami Nasr, Nadine Hamieh, Ziad Tayara, Charbel Saade
OBJECTIVE: To evaluate the performance of non-contrast computed tomography (CT) by reporting the difference in attenuation between normal and inflamed renal parenchyma in patients clinically diagnosed with acute pyelonephritis (APN). MATERIAL AND METHODS: This is a retrospective study concerned with non-contrast CT evaluation of 74 patients, admitted with a clinical diagnosis of APN and failed to respond to 48h antibiotics treatment. Mean attenuation values in Hounsfield units (HU) were measured in the upper, middle and lower segments of the inflamed and the normal kidney of the same patient...
September 18, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29049949/rhinovirus-viremia-in-adult-patients-with-high-viral-load-in-bronchoalveolar-lavages
#19
Anneloes L Van Rijn, Eric C Claas, Peter A von dem Borne, Aloys C M Kroes, Jutte J C de Vries
BACKGROUND: In children, rhinovirus viremia has been associated with higher nasopharyngeal loads and increase in severity of clinical signs and symptoms. OBJECTIVES: This study aims to detect rhinovirus viremia in adult patients and to establish potential correlations with the clinical course. STUDY DESIGN: Adult patients with rhinovirus strongly positive bronchoalveolar lavages (BAL, quantitation cycle, Cq values <25) detected between 2008 and 2014 were studied retrospectively...
October 12, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29042471/measuring-patient-perception-of-quality-in-a-radiology-department-by-adapting-a-standardized-industry-proven-tool
#20
Farouk Dako, Rick Wray, Omer Awan, Rathan M Subramaniam
Introduction: Our study quantitatively measures patient perception of quality and satisfaction in a PET-CT center at the point of care using a psychometrically validated questionnaire, SERVPERF, to guide subsequent quality improvement interventions. SERVPERF is a survey instrument that captures service quality by measuring performance of various services. It has demonstrated reliability and validity across various industries including healthcare, banking, transportation, telecommunication and higher education...
October 17, 2017: Journal of Nuclear Medicine Technology
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