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Quantitative radiology

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https://www.readbyqxmd.com/read/28813195/prediction-of-therapeutic-response-of-hepatocellular-carcinoma-to-transcatheter-arterial-chemoembolization-based-on-pretherapeutic-dynamic-ct-and-textural-findings
#1
Hyun Jeong Park, Jung Hoon Kim, Seo-Youn Choi, Eun Sun Lee, Sang Joon Park, Jae Young Byun, Byung Ihn Choi
OBJECTIVE: The objective of our study was to assess the value of CT texture analysis for prediction of therapeutic response of hepatocellular carcinoma (HCC) to transcatheter arterial chemoembolization (TACE) with pretherapeutic dynamic CT. MATERIALS AND METHODS: We retrospectively analyzed 132 HCCs in 96 patients treated with TACE who underwent dynamic CT before initial TACE. Imaging findings and arterial enhancement ratios were analyzed. All HCCs were manually segmented, and their texture features were quantitatively extracted using in-house software...
August 16, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28777485/pls3-deletions-lead-to-severe-spinal-osteoporosis-and-disturbed-bone-matrix-mineralization
#2
Kämpe Aj, Costantini A, Levy-Shraga Y, Zeitlin L, Roschger P, Taylan F, Lindstrand A, Paschalis Ep, Gamsjaeger S, Raas-Rothschild A, Hövel M, Jiao H, Klaushofer K, Grasemann C, Mäkitie O
Mutations in the PLS3 gene, encoding Plastin 3, were described in 2013 as a cause for X-linked primary bone fragility in children. The specific role of PLS3 in bone metabolism remains inadequately understood. Here we describe for the first time PLS3 deletions as the underlying cause for childhood-onset primary osteoporosis in three boys from two families. We carried out thorough clinical, radiological and bone tissue analyses to explore the consequences of these deletions and to further elucidate the role of PLS3 in bone homeostasis...
August 4, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28776434/pneumonia-in-mechanically-ventilated-patients-no-diagnostic-and-prognostic-value-of-different-quantitative-tracheal-aspirates-thresholds
#3
J Garnacho-Montero, A Gutiérrez-Pizarraya, I Lopez-García, J C Miranda, V González-Galán, Y Corcia-Palomo, I Alonso-Araujo, L Martín-Villén, J Aznar-Martín, R Amaya-Villar
BACKGROUND: Diagnosis of pneumonia in ventilated patients is challenging due to the lack of specific and definitive clinical symptoms, laboratory data or radiological abnormalities. METHODS: Based on quantitative tracheal aspirate (QTA) results, three groups of patients were compared: <10(5) cfu/ml, ≥10(5) cfu/ml and <10(6) cfu/ml, and ≥10(6) cfu/ml. We recorded demographic variables, underlying diseases and severity of illness at ICU admission...
August 4, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28753252/utility-and-reproducibility-of-3-dimensional-printed-models-in-pre-operative-planning-of-complex-thoracic-tumors
#4
Elizabeth George, Maria Barile, Anji Tang, Ory Wiesel, Antonio Coppolino, Andreas Giannopoulos, Steven Mentzer, Michael Jaklitsch, Andetta Hunsaker, Dimitrios Mitsouras
BACKGROUND AND OBJECTIVES: 3D-printed models are increasingly used for surgical planning. We assessed the utility, accuracy, and reproducibility of 3D printing to assist visualization of complex thoracic tumors for surgical planning. METHODS: Models were created from pre-operative images for three patients using a standard radiology 3D workstation. Operating surgeons assessed model utility using the Gillespie scale (1 = inferior to 4 = superior), and accuracy compared to intraoperative findings...
September 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28752205/post-operative-radiological-predictors-of-satisfying-outcomes-occurring-after-intra-articular-calcaneal-fractures-a-three-dimensional-ct-quantitative-evaluation
#5
Minfei Qiang, Yanxi Chen, Xiaoyang Jia, Kun Zhang, Haobo Li, Yuchen Jiang, Yijie Zhang
PURPOSE: No functional outcome related to 3-D CT evaluations for calcaneal fractures has been presented. The aims of this study are to analyze the post-operative morphological parameters of calcaneal fractures in 3-D space and to correlate the 3-D morphological parameters with functional outcomes. METHODS: Between 2009 and 2015, 156 patients operatively treated for displaced calcaneal fractures were retrospectively reviewed with an average follow-up time of 32.4 months...
July 27, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28732135/synovial-immunophenotype-and-anti-citrullinated-protein-antibodies-in-ra-patients-relationship-to-treatment-response-and-radiological-prognosis
#6
Carl Orr, Aurelie Najm, Monika Biniecka, Trudy McGarry, Chin-Teck Ng, Francis Young, Ursula Fearon, Douglas J Veale
OBJECTIVE: Serum anti-citrullinated peptide antibodies (ACPA) may be present before development of rheumatoid arthritis (RA) and may predict more severe, erosive disease. This study examines synovial tissue immunophenotype according to ACPA status in RA patients, response to treatment and erosive status. METHODS: Consecutive RA patients were prospectively recruited and underwent clinical and serological assessment before and after treatment. Radiological assessment was performed at the time of clinical follow up...
July 21, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28728431/radiographic-temporal-subtraction-analysis-can-detect-finger-joint-space-narrowing-progression-in-rheumatoid-arthritis-with-clinical-low-disease-activity
#7
Taichi Okino, Tamotsu Kamishima, Kenneth Lee Sutherland, Jun Fukae, Akihiro Narita, Shota Ichikawa, Kazuhide Tanimura
Background Recent papers suggest that finger joints with positive synovial vascularity (SV) assessed by ultrasonography under clinical low disease activity (CLDA) in rheumatoid arthritis (RA) patients may cause joint space narrowing (JSN) progression. Purpose To investigate the performance of a computer-based method by directly comparing with the conventional scoring method in terms of the detectability of JSN progression in hand radiography of RA patients with CLDA. Material and Methods Fifteen RA patients (13 women, 2 men) with long-term sustained CLDA of >2 years were included...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28722766/comparative-analysis-of-the-radiology-of-osteoporotic-vertebral-fractures-in-women-and-men-cross-sectional-and-longitudinal-observations-from-the-canadian-multicentre-osteoporosis-study-camos
#8
Brian C Lentle, Claudie Berger, Linda Probyn, Jacques P Brown, Lisa Langsetmo, Ben Fine, Kevin Lian, Arvind K Shergill, Jacques Trollip, Stuart Jackson, William D Leslie, Jerilynn C Prior, Stephanie M Kaiser, David A Hanley, Jonathan D Adachi, Tanveer Towheed, K Shawn Davison, Angela M Cheung, David Goltzman
We compared two methods for osteoporotic vertebral fracture (VF) assessment on lateral spine radiographs, the Genant semiquantitative (GSQ) technique and a modified algorithm-based qualitative (mABQ) approach. We evaluated 4465 women and 1771 men aged ≥50 years from the Canadian Multicentre Osteoporosis Study with available X-ray images at baseline. Observer agreement was lowest for grade 1 VFs determined by GSQ. Among physician readers, agreement was greater for VFs diagnosed by mABQ (ranging from 0.62 [95% confidence interval (CI) 0...
July 19, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28719143/osteoporotic-vertebral-fracture-prevalence-varies-widely-between-radiological-assessment-methods-the-rotterdam-study
#9
L Oei, F Koromani, S J Breda, J T Schousboe, E M Clark, Jbj van Meurs, M A Ikram, J H Waarsing, Fja van Rooij, M C Zillikens, G P Krestin, Ehg Oei, F Rivadeneira
BACKGROUND: Accurate diagnosis of vertebral osteoporotic fractures is crucial for the identification of individuals at high risk of future fractures. Different methods for radiological assessment of vertebral fractures exist, but a gold standard is lacking. The aim of our study was to estimate statistical measures of agreement and prevalence of osteoporotic vertebral fractures in the population-based Rotterdam Study, across the two most commonly applied assessment methods. METHODS: The quantitative morphometry (QM) method, evaluates vertebral height loss that affects vertebral shape whereas the algorithm based qualitative (ABQ) method judges endplate integrity and includes guidelines for the differentiation of vertebral fracture and non- fracture deformities...
July 18, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28718993/role-of-fdg-pet-mri-fdg-pet-ct-and-dynamic-susceptibility-contrast-perfusion-mri-in-differentiating-radiation-necrosis-from-tumor-recurrence-in-glioblastomas
#10
Mojgan Hojjati, Chaitra Badve, Vasant Garg, Curtis Tatsuoka, Lisa Rogers, Andrew Sloan, Peter Faulhaber, Pablo R Ros, Leo J Wolansky
BACKGROUND AND PURPOSE: To compare the utility of quantitative PET/MRI, dynamic susceptibility contrast (DSC) perfusion MRI (pMRI), and PET/CT in differentiating radiation necrosis (RN) from tumor recurrence (TR) in patients with treated glioblastoma multiforme (GBM). METHODS: The study included 24 patients with GBM treated with surgery, radiotherapy, and temozolomide who presented with progression on imaging follow-up. All patients underwent PET/MRI and pMRI during a single examination...
July 18, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28716246/cognitive-impairment-predicts-worse-short-term-response-to-spinal-tap-test-in-normal-pressure-hydrocephalus
#11
Thomas Wolfsegger, Raffi Topakian
INTRODUCTION: In patients with idiopathic normal pressure hydrocephalus (iNPH), the spinal tap test (STT) is commonly used to predict ventriculoperitoneal shunt responsiveness. Clinical improvement following STT usually is measured by testing gait function. In our study, we investigated the impact of cognitive impairment on gait improvement after STT. METHODS: 22 patients with the clinical and radiological diagnosis of iNPH underwent gait analyses (mobile measuring system Medilogic) before and 2-4h after STT in self-paced gait velocity over 7m...
August 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28707256/monitoring-in-vivo-the-mammary-gland-microstructure-during-morphogenesis-from-lactation-to-post-weaning-using-diffusion-tensor-mri
#12
Noam Nissan, Edna Furman-Haran, Myra Shapiro-Feinberg, Dov Grobgeld, Hadassa Degani
Lactation and the return to the pre-conception state during post-weaning are regulated by hormonal induced processes that modify the microstructure of the mammary gland, leading to changes in the features of the ductal / glandular tissue, the stroma and the fat tissue. These changes create a challenge in the radiological workup of breast disorder during lactation and early post-weaning. Here we present non-invasive MRI protocols designed to record in vivo high spatial resolution, T2-weighted images and diffusion tensor images of the entire mammary gland...
July 13, 2017: Journal of Mammary Gland Biology and Neoplasia
https://www.readbyqxmd.com/read/28696850/advanced-mr-imaging-techniques-for-differentiation-of-neuropathic-arthropathy-and-osteomyelitis-in-the-diabetic-foot
#13
Teodoro Martín Noguerol, Antonio Luna Alcalá, Luis S Beltrán, Marta Gómez Cabrera, Jordi Broncano Cabrero, Joan C Vilanova
Diagnosis and treatment of foot disease in patients with diabetes is a common clinical-radiologic challenge, particularly the differentiation of neuropathic arthropathy from osteomyelitis. Conventional clinical tests and imaging techniques have limited accuracy for evaluation of the diabetic foot. The introduction of morphologic magnetic resonance (MR) imaging in these patients has provided a qualitative leap in diagnosis. The characteristics of soft-tissue and bone marrow edema and their patterns of distribution throughout the foot allow discrimination between both entities...
July 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28694111/the-pathophysiology-of-watershed-infarction-a-three-dimensional-time-of-flight-magnetic-resonance-angiography-study
#14
Caroline Weill, Laurent Suissa, Jacques Darcourt, Marie-Hélène Mahagne
BACKGROUND: Most of the time, watershed infarcts (WIs) involve steno-occlusive carotid disease. The pathophysiological mechanism could be predicted by their pattern: internal WIs (IWIs) are thought to be due to hemodynamic impairment in contrast to cortical WIs (CWIs), which are more likely to be caused by microembolic phenomena. We used a 3D time-of-flight (TOF) magnetic resonance angiography (MRA) study to assess this hypothesis. METHODS: In 45 consecutive patients with a recent WI and ipsilateral cervical carotid stenosis, clinical and radiological data were obtained retrospectively...
September 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28691528/ribbing-disease-a-systematic-review
#15
Bart G Pijls, Koen Steentjes, Jan W Schoones, Sander Pd Dijkstra
Background Ribbing disease, or multiple diaphyseal sclerosis, is a rare benign bone dysplasia. Purpose To systematically review the literature to determine the clinical and radiological presentation of patients with Ribbing disease as well as the effects of attempted treatments. Material and Methods We considered individual patient data of patients diagnosed with Ribbing disease derived from patient reports and patient series. All stages of the review were performed by two reviewers independently. Standard descriptive statistics were used for quantitative analyses and mixed model analyses were used when appropriate Results The literature search yielded 420 unique hits of which 23 studies were included, covering a total of 40 patients of whom 29 had bilateral involvement...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28688156/comparison-and-combination-of-strain-and-shear-wave-elastography-of-breast-masses-for-differentiation-of-benign-and-malignant-lesions-by-quantitative-assessment-preliminary-study
#16
Mirinae Seo, Hye Shin Ahn, Sung Hee Park, Jong Beum Lee, Byung Ihn Choi, Yu-Mee Sohn, So Youn Shin
OBJECTIVES: To compare the diagnostic performance of strain and shear wave elastography of breast masses for quantitative assessment in differentiating benign and malignant lesions and to evaluate the diagnostic accuracy of combined strain and shear wave elastography. METHODS: Between January and February 2016, 37 women with 45 breast masses underwent both strain and shear wave ultrasound (US) elastographic examinations. The American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) final assessment on B-mode US imaging was assessed...
July 8, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28680874/the-potential-benefits-of-applying-recent-advances-in-esophageal-motility-testing-in-patients-with-esophageal-atresia
#17
REVIEW
Nathalie Rommel, Maissa Rayyan, Charlotte Scheerens, Taher Omari
Infants and children with esophageal atresia commonly present with swallowing dysfunction or dysphagia. Dysphagia can lead to a range of significant consequences such as aspiration pneumonia, malnutrition, dehydration, and food impaction. To improve oral intake, the clinical diagnosis of dysphagia in patients with esophageal atresia should focus on both the pharynx and the esophagus. To characterize the complex interactions of bolus flow and motor function between mouth, pharynx, and esophagus, a detailed understanding of normal and abnormal deglutition is required through the use of adequate and objective assessment techniques...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28679024/multi-pronged-proteomic-analysis-to-study-the-glioma-pathobiology-using-cerebrospinal-fluid-samples
#18
Nikita Gahoi, Darpan Malhotra, Aliasgar Moiyadi, Santosh G Varma, Mayuri N Gandhi, Sanjeeva Srivastava
PURPOSE: Gliomas are one of the most aggressive and lethal brain tumors arising from neoplastic transformation of astrocytes and oligodendrocytes. In this study, we have carried out a comprehensive quantitative analysis of proteome level differences in cerebrospinal fluid (CSF) across different grades of gliomas for a better understanding of glioma pathobiology. EXPERIMENTAL DESIGN: Glioma patients were diagnosed by radiology and histochemistry- based analyses. Differential proteomic analysis of high (n = 12) and low (n = 8) grade gliomas, and control (n = 3) samples was performed by using two complementary quantitative proteomic approaches; 2D-DIGE and iTRAQ...
July 5, 2017: Proteomics. Clinical Applications
https://www.readbyqxmd.com/read/28674518/brain-susceptibility-changes-in-a-patient-with-natalizumab-related-progressive-multifocal-leukoencephalopathy-a-longitudinal-quantitative-susceptibility-mapping-and-relaxometry-study
#19
Giuseppe Pontillo, Sirio Cocozza, Roberta Lanzillo, Pasquale Borrelli, Anna De Rosa, Vincenzo Brescia Morra, Enrico Tedeschi, Giuseppe Palma
BACKGROUND: Brain MRI plays an essential role in both diagnosis and follow-up of the JC virus infection of the brain. Recently, MR studies with susceptibility-weighted imaging (SWI) sequences have shown hypointensities in U-fibers adjacent to white matter (WM) lesions of progressive multifocal leukoencephalopathy (PML). This finding has been confirmed with the use of quantitative susceptibility mapping (QSM), allowing to hypothesize a paramagnetic effect in these regions. Here, we report the first longitudinal assessment of QSM and R2* maps in natalizumab-associated PML to evaluate serial changes in susceptibility contrast images and their role in PML diagnosis and follow-up...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28669431/radiology-online-patient-education-materials-provided-by-major-university-hospitals-do-they-conform-to-nih-and-ama-guidelines
#20
Arpan V Prabhu, Ashley L Donovan, Tudor Crihalmeanu, David R Hansberry, Nitin Agarwal, Sushil Beriwal, Hrishikesh Kale, Matthew Heller
AIMS: The internet creates opportunities for Americans to access medical information about imaging tests and modalities to guide them in their medical decision-making. Owing to health literacy variations in the general population, the American Medical Association and National Institutes of Health recommend patient education resources to be written between the third and seventh grade levels. Our purpose is to quantitatively assess the readability levels of online radiology educational materials, written for the public, in 20 major university hospitals...
May 22, 2017: Current Problems in Diagnostic Radiology
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