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Quantitative radiology

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https://www.readbyqxmd.com/read/27908253/assessment-of-bone-quality-in-osteoporosis-treatment-with-bone-anabolic-agents-really-something-new
#1
Fabio Massimo Ulivieri, Renata Caudarella, Marzia Camisasca, Daniela Maria Cabrini, Ilaria Merli, Carmelo Messina, Luca Petruccio Piodi
Osteoporosis is a chronic pathologic condition, particularly of the elderly, in which a reduction of bone mineral density (BMD) weakens bone, leading to the so-called fragility fractures, most often of spine and femur. The gold standard exam for the quantitative measurement of BMD is the dual X-ray photon absorptiometry (DXA), a radiological method. However, a relevant number of fragility fractures occurs in the range of normal BMD values, meaning that also qualitative aspects of bone play a role, namely bone architecture and bone geometry...
December 1, 2016: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/27903193/three-dimensional-assessment-of-the-effects-of-high-density-embolization-material-on-the-absorbed-dose-in-the-target-for-gamma-knife-radiosurgery-of-arteriovenous-malformations
#2
Yoichi Watanabe, Divyajot Sandhu, Leighton Warmington, Sean Moen, Ramachandra Tummala
OBJECTIVE Arteriovenous malformation (AVM) is an intracranial vascular disorder. Gamma Knife radiosurgery (GKRS) is used in conjunction with intraarterial embolization to eradicate the nidus of AVMs. Clinical results indicate that patients with prior embolization tend to gain less benefit from GKRS. The authors hypothesized that this was partly caused by dosimetric deficiency. The actual dose delivered to the target may be smaller than the intended dose because of increased photon attenuation by high-density embolic materials...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27890986/correlation-of-chest-computed-tomography-findings-with-dyspnea-and-lung-functions-in-post-tubercular-sequelae
#3
Ananya Panda, Ashu Seith Bhalla, Raju Sharma, Anant Mohan, Vishnu Sreenivas, Umasankar Kalaimannan, Ashish Dutt Upadhyay
AIMS: To study the correlation between dyspnea, radiological findings, and pulmonary function tests (PFTs) in patients with sequelae of pulmonary tuberculosis (TB). MATERIALS AND METHODS: Clinical history, chest computed tomography (CT), and PFT of patients with post-TB sequelae were recorded. Dyspnea was graded according to the Modified Medical Research Council (mMRC) scale. CT scans were analyzed for fibrosis, cavitation, bronchiectasis, consolidation, nodules, and aspergilloma...
November 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27880938/pathologic-stratification-of-operable-lung-adenocarcinoma-using-radiomics-features-extracted-from-dual-energy-ct-images
#4
Jung Min Bae, Ji Yun Jeong, Ho Yun Lee, Insuk Sohn, Hye Seung Kim, Ji Ye Son, O Jung Kwon, Joon Young Choi, Kyung Soo Lee, Young Mog Shim
PURPOSE: To evaluate the usefulness of surrogate biomarkers as predictors of histopathologic tumor grade and aggressiveness using radiomics data from dual-energy computed tomography (DECT), with the ultimate goal of accomplishing stratification of early-stage lung adenocarcinoma for optimal treatment. RESULTS: Pathologic grade was divided into grades 1, 2, and 3. Multinomial logistic regression analysis revealed i-uniformity and 97.5th percentile CT attenuation value as independent significant factors to stratify grade 2 or 3 from grade 1...
November 21, 2016: Oncotarget
https://www.readbyqxmd.com/read/27878338/reporting-standards-for-the-imaging-based-diagnosis-of-renal-masses-on-ct-and-mri-a-national-survey-of-academic-abdominal-radiologists-and-urologists
#5
Matthew S Davenport, Eric M Hu, Andrew D Smith, Hersh Chandarana, Khaled Hafez, Ganesh S Palapattu, J Stuart Wolf, Stuart G Silverman
PURPOSE: To define important elements of a structured radiology report of a CT or MRI performed to evaluate an indeterminate renal mass. METHODS: IRB approval was waived for this multi-site prospective quality improvement study. A 35-question survey investigating elements of a CT or MRI report describing a renal mass was created through an iterative process by the Society of Abdominal Radiology Disease-Focused Panel on renal cell carcinoma. Surveys were distributed to consenting abdominal radiologists and urologists at nine academic institutions...
November 22, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27865797/radboud-centre-for-mitochondrial-medicine-pediatric-mri-score
#6
Sheila Suet-Na Wong, Bozena Goraj, Cheuk-Wing Fung, Jeroen Vister, Lonneke de Boer, Saskia Koene, Jan Smeitink
We developed the first user-friendly, semi-quantitative, and quick-to-perform Radboud Centre for Mitochondrial Medicine Pediatric MRI score (RCMM-PMRIS), focusing on the six most commonly described neuroimaging abnormalities in the literature. The RCMM-PMRIS was validated through individual review of 30 sets of brain MRI studies in 24 patients with genetically confirmed mitochondrial disorders by six raters. The application of RCMM-PMRIS can help to define the extent of the brain involvement and therefore to assess the radiological mitochondrial disease severity, to monitor disease progression and consequently to act as an outcome measure for treatment effects in patients with mitochondrial disease...
November 16, 2016: Mitochondrion
https://www.readbyqxmd.com/read/27862628/history-physical-exam-laboratory-testing-and-emergency-department-ultrasonography-for-the-diagnosis-of-acute-cholecystitis
#7
Ashika Jain, Ninfa Mehta, Michael Secko, Joshua Schecter, Dimitri Papanagnou, Shreya Pandya, Richard Sinert
BACKGROUND: Acute Cholecystitis (AC) is a common differential for patients presenting to the Emergency Department (ED) with abdominal pain. The diagnostic accuracy of history, physical exam and bedside lab tests for AC have not been quantitatively described. OBJECTIVES: We performed a systematic review to determine the utility of History/Physical exam (H&P), Laboratory studies and Ultrasonography (US) in diagnosing AC in the ED. METHODS: We searched medical literature from January 1965 to March 2016 in PubMed, EMBASE and SCOPUS using a strategy derived from the following formulation of our clinical question: Patients: ED patients suspected of AC...
November 15, 2016: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/27846229/microrna-expression-for-early-prediction-of-late-occurring-hematologic-acute-radiation-syndrome-in-baboons
#8
Matthias Port, Francis Herodin, Marco Valente, Michel Drouet, Reinhard Ullmann, Sven Doucha-Senf, Andreas Lamkowski, Matthäus Majewski, Michael Abend
For effective medical management of radiation-exposed persons after a radiological/nuclear event, blood-based screening measures in the first few days that could predict hematologic acute radiation syndrome (HARS) are needed. For HARS severity prediction, we used microRNA (miRNA) expression changes measured on days one and two after irradiation in a baboon model. Eighteen baboons underwent different patterns of partial or total body irradiation, corresponding to an equivalent dose of 2.5 or 5 Gy. According to changes in blood cell counts (BCC) the surviving baboons (n = 17) exhibited mild (H1-2, n = 4) or more severe (H2-3, n = 13) HARS...
2016: PloS One
https://www.readbyqxmd.com/read/27833411/the-impact-of-iterative-reconstruction-in-low-dose-computed-tomography-on-the-evaluation-of-diffuse-interstitial-lung-disease
#9
Hyun-Ju Lim, Myung Jin Chung, Kyung Eun Shin, Hye Sun Hwang, Kyung Soo Lee
OBJECTIVE: To evaluate the impact of iterative reconstruction (IR) on the assessment of diffuse interstitial lung disease (DILD) using CT. MATERIALS AND METHODS: An American College of Radiology (ACR) phantom (module 4 to assess spatial resolution) was scanned with 10-100 effective mAs at 120 kVp. The images were reconstructed using filtered back projection (FBP), adaptive statistical iterative reconstruction (ASIR), with blending ratios of 0%, 30%, 70% and 100%, and model-based iterative reconstruction (MBIR), and their spatial resolution was objectively assessed by the line pair structure method...
November 2016: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/27832795/bone-histomorphometric-changes-in-children-with-rheumatic-disorders-on-chronic-glucocorticoids
#10
Jennifer Harrington, Douglas Holmyard, Earl Silverman, Etienne Sochett, Marc Grynpas
BACKGROUND: Rheumatic diseases are associated with an increased fracture risk. The tissue level characteristics of the bone involvement in children have not been well elucidated. Our objectives were to describe the bone micro-architectural characteristics in children with rheumatic diseases on chronic glucocorticoids, and to determine associations between micro-architectural findings with clinical and radiological variables. METHODS: Children on chronic glucocorticoids for an underlying rheumatic disease were referred for evaluation of bone fragility given the presence of vertebral compression fractures...
November 10, 2016: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/27799242/evaluation-of-clinicians-knowledge-and-practices-regarding-medical-radiological-exposure-findings-from-a-mixed-methods-investigation-survey-and-qualitative-study
#11
B Lumbreras, J Vilar, I González-Álvarez, M Guilabert, L A Parker, M Pastor-Valero, M L Domingo, M F Fernández-Lorente, I Hernández-Aguado
OBJECTIVES: To assess the impact of initiatives aiming to increase clinician awareness of radiation exposure; to explore the challenges they face when communicating with patients; to study what they think is the most appropriate way of communicating the long-term potential risks of medical radiological exposure to patients. DESIGN: A quantitative and qualitative evaluation through a survey and focal groups. SETTING: San Juan Hospital and Dr Peset Hospital (Southeast Spain) and clinicians from Spanish scientific societies...
October 31, 2016: BMJ Open
https://www.readbyqxmd.com/read/27790358/study-of-fruit-and-vegetable-intake-in-breast-cancer-patients-in-the-city-of-sabzevar
#12
Akram Kooshki, Manidgeh Yousefi Moghaddam, Roya Akbarzadeh
INTRODUCTION: Diet is one of the most important modifiable risk factors for prevention and control of chronic diseases, including breast cancer. This study aimed to determine the fruit and vegetable intake in women with cancer breast in Sabzevar. METHODS: This cross-sectional study was conducted on 125 women with breast cancer in Sabzevar in 2011. Census sampling was done on volunteers in a visiting home and suspected women referred to the mammography, ultrasound, and radiology clinic in the Sabzevar center for breast cancer...
September 2016: Electronic Physician
https://www.readbyqxmd.com/read/27779124/automated-segmentation-of-liver-and-liver-cysts-from-bounded-abdominal-mr-images-in-patients-with-autosomal-dominant-polycystic-kidney-disease
#13
Youngwoo Kim, Sonu K Bae, Tianming Cheng, Cheng Tao, Yinghui Ge, Arlene B Chapman, Vincente E Torres, Alan S L Yu, Michal Mrug, William M Bennett, Michael F Flessner, Doug P Landsittel, Kyongtae T Bae
Liver and liver cyst volume measurements are important quantitative imaging biomarkers for assessment of disease progression in autosomal dominant polycystic kidney disease (ADPKD) and polycystic liver disease (PLD). To date, no study has presented automated segmentation and volumetric computation of liver and liver cysts in these populations. In this paper, we proposed an automated segmentation framework for liver and liver cysts from bounded abdominal MR images in patients with ADPKD. To model the shape and variations in ADPKD livers, the spatial prior probability map (SPPM) of liver location and the tissue prior probability maps (TPPMs) of liver parenchymal tissue intensity and cyst morphology were generated...
November 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27778168/visceral-to-subcutaneous-fat-ratio-predicts-acuity-of-diverticulitis
#14
Salvatore Docimo, Young Lee, Prav Chatani, Ann M Rogers, Frank Lacqua
INTRODUCTION: There is an association between obesity and more complicated diverticular disease. We hypothesize that this link may be due to an increased level of visceral fat rather than an elevated body mass index alone. Adipose tissue secretes inflammatory cytokines, and chronic inflammation may account for the link between obesity and a more severe presentation of diverticular disease. We have applied a quantitative measure of visceral fat content in a series of patients admitted with diverticulitis, comparing those who required emergent versus elective surgical procedures for diverticulitis...
October 24, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27774334/brain-mr-contribution-to-the-differential-diagnosis-of-parkinsonian-syndromes-an-update
#15
Giovanni Rizzo, Stefano Zanigni, Roberto De Blasi, Daniela Grasso, Davide Martino, Rodolfo Savica, Giancarlo Logroscino
Brain magnetic resonance (MR) represents a useful and feasible tool for the differential diagnosis of Parkinson's disease. Conventional MR may reveal secondary forms of parkinsonism and may show peculiar brain alterations of atypical parkinsonian syndromes. Furthermore, advanced MR techniques, such as morphometric-volumetric analyses, diffusion-weighted imaging, diffusion tensor imaging, tractography, proton MR spectroscopy, and iron-content sensitive imaging, have been used to obtain quantitative parameters useful to increase the diagnostic accuracy...
2016: Parkinson's Disease
https://www.readbyqxmd.com/read/27773345/evaluating-affordable-cranial-ultrasonography-in-east-african-neonatal-intensive-care-units
#16
David E Clay, Annika C Linke, Daniel J Cameron, Bobby Stojanoski, Stephen Rulisa, Aggrey Wasunna, Sandrine de Ribaupierre, Rhodri Cusack
Neuroimaging is a valuable diagnostic tool for the early detection of neonatal brain injury, but equipment and radiologic staff are expensive and unavailable to most hospitals in developing countries. We evaluated an affordable, portable ultrasound machine as a quantitative and qualitative diagnostic tool and to establish whether a novice sonographer could effectively operate the equipment and obtain clinically important information. Cranial ultrasonography was performed on term healthy, pre-term and term asphyxiated neonates in Rwandan and Kenyan hospitals...
January 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27762080/a-proposed-approach-for-quantitative-benefit-risk-assessment-in-diagnostic-radiology-guideline-development-the-american-college-of-radiology-appropriateness-criteria-example
#17
Maria Agapova, Brian B Bresnahan, Mitchell Higashi, Larry Kessler, Louis P Garrison, Beth Devine
The American College of Radiology develops evidence-based practice guidelines to aid appropriate utilization of radiological procedures. Panel members use expert opinion to weight trade-offs and consensus methods to rate appropriateness of imaging tests. These ratings include an equivocal range, assigned when there is disagreement about a technology's appropriateness and the evidence base is weak or for special circumstances. It is not clear how expert consensus merges with the evidence base to arrive at an equivocal rating...
October 19, 2016: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/27744213/temporal-variation-of-dose-rate-distribution-around-the-fukushima-daiichi-nuclear-power-station-using-unmanned-helicopter
#18
Yukihisa Sanada, Tadashi Orita, Tatsuo Torii
Aerial radiological survey using an unmanned aerial vehicle (UAV) was applied to measurement surface contamination around the Fukushima Daiichi nuclear power station (FDNPS). An unmanned helicopter monitoring system (UHMS) was developed to survey the environmental effect of radioactive cesium scattered as a result of the FDNPS accident. The UHMS was used to monitor the area surrounding the FDNPS six times from 2012 to 2015. Quantitative changes in the radioactivity distribution trend were revealed from the results of these monitoring runs...
October 3, 2016: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/27742112/radiomics-in-brain-tumors-an-emerging-technique-for-characterization-of-tumor-environment
#19
Aikaterini Kotrotsou, Pascal O Zinn, Rivka R Colen
The role of radiomics in the diagnosis, monitoring, and therapy planning of brain tumors is becoming increasingly clear. Incorporation of quantitative approaches in radiology, in combination with increased computer power, offers unique insights into macroscopic tumor characteristics and their direct association with the underlying pathophysiology. This article presents the most recent findings in radiomics and radiogenomics with respect to identifying potential imaging biomarkers with prognostic value that can lead to individualized therapy...
November 2016: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/27739409/quantitative-assessment-of-provability-of-radiation-related-cancers-considering-unavoidable-existence-of-unadjusted-risk-factors
#20
H Ogino, Y Fujimichi, M Sasaki, N Hamada, T Iwasaki, K Yoshida, T Hattori
The attribution of stochastic effects to exposure to ionizing radiation has been qualitatively discussed by introducing two distinct concepts of provability and probability. This study aims to develop a method of quantitatively assessing the provability of radiation-related cancers. To this end, the 'minimum provable dose' (MPD) was developed and applied to actual cancer mortality in Japan. The background lifetime risk of cancer mortality was calculated for the esophagus, stomach, colon, liver, lungs, skin, breasts, ovaries, bladder, and bone marrow as well as the age-specific risk coefficients reproducing those given in the 2007 Recommendations of the International Commission on Radiological Protection (ICRP)...
October 14, 2016: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
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