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Quantitative radiology

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https://www.readbyqxmd.com/read/29340779/dose-image-quality-and-spine-modeling-assessment-of-biplanar-eos-micro-dose-radiographs-for-the-follow-up-of-in-brace-adolescent-idiopathic-scoliosis-patients
#1
Baptiste Morel, Sonia Moueddeb, Eleonore Blondiaux, Stephen Richard, Manon Bachy, Raphael Vialle, Hubert Ducou Le Pointe
PURPOSE: The aim of this study was to compare the radiation dose, image quality and 3D spine parameter measurements of EOS low-dose and micro-dose protocols for in-brace adolescent idiopathic scoliosis (AIS) patients. METHODS: We prospectively included 25 consecutive patients (20 females, 5 males) followed for AIS and undergoing brace treatment. The mean age was 12 years (SD 2 years, range 8-15 years). For each patient, in-brace biplanar EOS radiographs were acquired in a standing position using both the conventional low-dose and micro-dose protocols...
January 16, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29326049/quantitative-ct-assessment-of-gynecomastia-in-the-general-population-and-in-dialysis-cirrhotic-and-obese-patients
#2
Eyal Klang, Nayroz Kanana, Alon Grossman, Steve Raskin, Jana Pikovsky, Miri Sklair, Lior Heller, Shelly Soffer, Edith M Marom, Eli Konen, Marianne Michal Amitai
RATIONALE AND OBJECTIVES: Gynecomastia is the benign enlargement of the male breast because of proliferation of the glandular component. To date, there is no radiological definition of gynecomastia and no quantitative evaluation of breast glandular tissues in the general male population. The aims of this study were to supply radiological-based measurements of breast glandular tissue in the general male population, to quantitatively assess the prevalence of gynecomastia according to age by decades, and to evaluate associations between gynecomastia and obesity, cirrhosis, and dialysis...
January 8, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29325186/qualitative-and-quantitative-radiological-measures-of-fracture-healing
#3
John R Field, Greg R Ruthenbeck
The formulation of appropriate postoperative strategies, following fracture repair, currently involves an understanding of radiological and clinical outcome measures. This study has evaluated several modalities used to assess the progression of bone healing in a sheep tibial segmental defect model. Measures of defect optical density and volumetric data including bone density (BD), bone volume (BV) and bone mass (BM) were compared with qualitative data involving visual appraisal of radiographs [% bridging callus and modified radiographic union score tibia (mRUST)] and a clinical outcome measure (locomotory function)...
January 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29324560/contrast-media-extravasations-in-patients-undergoing-computerized-tomography-scanning-a-systematic-review-and-meta-analysis-of-risk-factors-and-interventions
#4
Sandrine Ding, Nicole Richli Meystre, Cosmin Campeanu, Giuseppe Gullo
OBJECTIVE: To identify risk factors and interventions preventing or reducing contrast medium extravasation. INTRODUCTION: Computed tomography (CT) is a radiological examination essential for the diagnosis and monitoring of many diseases. It is often performed with the intravenous (IV) injection of contrast agents. Use of these products can result in a significant complication, extravasation, which is the accidental leakage of IV material into the surrounding tissue...
January 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29323746/the-acetabular-and-spino-pelvic-morphologies-are-different-in-subjects-with-symptomatic-cam-femoro-acetabular-impingement
#5
George Grammatopoulos, Andrew D Speirs, K C Geoffrey Ng, Charles Riviere, Kawan S Rakhra, Mario Lamontagne, Paul E Beaule
Acetabular and spino-pelvic (SP) morphological parameters are important determinants of hip joint dynamics. This prospective study aimed to determine whether acetabular and SP morphological differences exist between hips with and without cam morphology and between symptomatic and asymptomatic hips with cam morphology. A cohort of 67 patients/hips was studied. Hips were either asymptomatic with no cam (Controls, n = 18), symptomatic with cam (n = 26) or asymptomatic with cam (n = 23). CT-based quantitative assessments of femoral, acetabular, pelvic and spino-pelvic parameters were performed...
January 11, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29312871/patient-specific-three-dimensional-printing-for-pre-surgical-planning-in-hepatocellular-carcinoma-treatment
#6
Elizabeth Perica, Zhonghua Sun
Background: Recently, three-dimensional (3D) printing has shown great interest in medicine, and 3D printed models may be rendered as part of the pre-surgical planning process in order to better understand the complexities of an individual's anatomy. The aim of this study is to investigate the feasibility of utilising 3D printed liver models as clinical tools in pre-operative planning for resectable hepatocellular carcinoma (HCC) lesions. Methods: High-resolution contrast-enhanced computed tomography (CT) images were acquired and utilized to generate a patient-specific 3D printed liver model...
December 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29308604/towards-precision-medicine-from-quantitative-imaging-to-radiomics
#7
U Rajendra Acharya, Yuki Hagiwara, Vidya K Sudarshan, Wai Yee Chan, Kwan Hoong Ng
Radiology (imaging) and imaging-guided interventions, which provide multi-parametric morphologic and functional information, are playing an increasingly significant role in precision medicine. Radiologists are trained to understand the imaging phenotypes, transcribe those observations (phenotypes) to correlate with underlying diseases and to characterize the images. However, in order to understand and characterize the molecular phenotype (to obtain genomic information) of solid heterogeneous tumours, the advanced sequencing of those tissues using biopsy is required...
2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29291453/climate-change-and-landscape-development-in-post-closure-safety-assessment-of-solid-radioactive-waste-disposal-results-of-an-initiative-of-the-iaea
#8
T Lindborg, M Thorne, E Andersson, J Becker, J Brandefelt, T Cabianca, M Gunia, A T K Ikonen, E Johansson, V Kangasniemi, U Kautsky, G Kirchner, R Klos, R Kowe, A Kontula, P Kupiainen, A-M Lahdenperä, N S Lord, D J Lunt, J-O Näslund, M Nordén, S Norris, D Pérez-Sánchez, A Proverbio, K Riekki, A Rübel, L Sweeck, R Walke, S Xu, G Smith, G Pröhl
The International Atomic Energy Agency has coordinated an international project addressing climate change and landscape development in post-closure safety assessments of solid radioactive waste disposal. The work has been supported by results of parallel on-going research that has been published in a variety of reports and peer reviewed journal articles. The project is due to be described in detail in a forthcoming IAEA report. Noting the multi-disciplinary nature of post-closure safety assessments, here, an overview of the work is given to provide researchers in the broader fields of radioecology and radiological safety assessment with a review of the work that has been undertaken...
December 29, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29290259/radiomics-and-radiogenomics-in-lung-cancer-a-review-for-the-clinician
#9
REVIEW
Rajat Thawani, Michael McLane, Niha Beig, Soumya Ghose, Prateek Prasanna, Vamsidhar Velcheti, Anant Madabhushi
Lung cancer is responsible for a large proportion of cancer-related deaths across the globe, with delayed detection being perhaps the most significant factor for its high mortality rate. Though the National Lung Screening Trial argues for screening of certain at-risk populations, the practical implementation of these screening efforts has not yet been successful and remains in high demand. Radiomics refers to the computerized extraction of data from radiologic images, and provides unique potential for making lung cancer screening more rapid and accurate using machine learning algorithms...
January 2018: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29284291/the-use-of-quantitative-eeg-for-differentiating-frontotemporal-dementia-from-late-onset-bipolar-disorder
#10
Sinem Zeynep Metin, Turker Tekin Erguzel, Gulhan Ertan, Celal Salcini, Betul Kocarslan, Merve Cebi, Baris Metin, Oguz Tanridag, Nevzat Tarhan
The behavioral variant frontotemporal dementia (bvFTD) usually emerges with behavioral changes similar to changes in late-life bipolar disorder (BD) especially in the early stages. According to the literature, a substantial number of bvFTD cases have been misdiagnosed as BD. Since the literature lacks studies comparing differential diagnosis ability of electrophysiological and neuroimaging findings in BD and bvFTD, we aimed to show their classification power using an artificial neural network and genetic algorithm based approach...
December 1, 2017: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/29273322/radiologic-and-functional-analysis-of-compensatory-lung-growth-after-living-donor-lobectomy
#11
Kei Shikuma, Toyofumi F Chen-Yoshikawa, Tsuyoshi Oguma, Takeshi Kubo, Keiji Ohata, Masatsugu Hamaji, Atsushi Kawaguchi, Hideki Motoyama, Kyoko Hijiya, Akihiro Aoyama, Hisako Matsumoto, Shigeo Muro, Hiroshi Date
BACKGROUND: Whether compensatory lung growth occurs in adult humans is controversial. The aim of this study was to confirm compensatory lung growth by analyzing ipsilateral residual lung after lower lobectomy in living lung transplant donors with quantitative and qualitative computed tomography assessments. METHODS: Chest computed tomography and pulmonary function tests were performed in 31 eligible donors before and 1 year after donor lobectomy. Ipsilateral residual lung volume was measured with three-dimensional computed tomography volumetry...
December 19, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29261354/prospective-comparison-of-standard-versus-low-radiation-dose-ct-enterography-for-the-quantitative-assessment-of-crohn-disease
#12
Greg Rosenfeld, Jacqueline Brown, Patrick M Vos, Jonathon Leipsic, Robert Enns, Brian Bressler
OBJECTIVE: CT enterography (CTE) is sensitive and specific for active inflammatory changes of Crohn disease (CD), but its use has been limited by exposure to ionizing radiation. The objective of this study is to show the noninferiority of a model-based iterative reconstruction (MBIR) technique using lower radiation doses compared with standard-dose CTE in the assessment of CD. SUBJECTS AND METHODS: Patients referred to a hospital radiology department for CTE for the evaluation of CD underwent both a standard examination (used to generate filtered back-projection and adaptive statistical iterative reconstruction [ASIR] images) and low-dose MBIR CTE performed in a random sequence on the same day...
December 20, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29250567/multicenter-survey-of-pet-ct-protocol-parameters-that-affect-standardized-uptake-values
#13
Darrin Byrd, Rebecca Christopfel, John Buatti, Eduardo Moros, Sadek Nehmeh, Adam Opanowski, Paul Kinahan
Clinical trials that evaluate cancer treatments may benefit from positron emission tomography (PET) imaging, which for many cancers can discriminate between effective and ineffective treatments. However, the image metrics used to quantify disease and evaluate treatment may be biased by many factors related to clinical protocols and PET system settings, many of which are site- and/or manufacturer-specific. An observational study was conducted using two surveys that were designed to record key sources of bias and variability in PET imaging...
January 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29247372/smoking-related-lung-abnormalities-on-computed-tomography-images-comparison-with-pathological-findings
#14
REVIEW
Tae Iwasawa, Tamiko Takemura, Takashi Ogura
Smoking-related lung abnormalities are now an increasing public health concern. According to the findings of large-cohort studies, approximately 8% of smokers have interstitial lung abnormalities, which are associated with a relatively high risk of all-cause mortality. We reviewed the radiological and pathological findings of smoking-related interstitial lung diseases, such as respiratory bronchiolitis-interstitial lung disease, desquamative interstitial pneumonia, and airspace enlargement with fibrosis. We have also discussed the histological basis of unclassifiable interstitial pneumonia in smokers, which exhibits airway-centered cystic lesions with fibrosis...
December 15, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29241596/essentials-of-statistical-methods-for-assessing-reliability-and-agreement-in-quantitative-imaging
#15
Arash Anvari, Elkan F Halpern, Anthony E Samir
Quantitative imaging is increasing in almost all fields of radiological science. Modern quantitative imaging biomarkers measure complex parameters including metabolism, tissue microenvironment, tissue chemical properties or physical properties. In this paper, we focus on measurement reliability assessment in quantitative imaging. We review essential concepts related to measurement such as measurement variability and measurement error. We also discuss reliability study methods for intraobserver and interobserver variability, and the applicable statistical tests including: intraclass correlation coefficient, Pearson correlation coefficient, and Bland-Altman graphs and limits of agreement, standard error of measurement, and coefficient of variation...
December 11, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29233836/radiomic-features-are-superior-to-conventional-quantitative-computed-tomographic-metrics-to-identify-coronary-plaques-with-napkin-ring-sign
#16
Márton Kolossváry, Júlia Karády, Bálint Szilveszter, Pieter Kitslaar, Udo Hoffmann, Béla Merkely, Pál Maurovich-Horvat
BACKGROUND: Napkin-ring sign (NRS) is an independent prognostic imaging marker of major adverse cardiac events. However, identification of NRS is challenging because of its qualitative nature. Radiomics is the process of extracting thousands of quantitative parameters from medical images to create big-data data sets that can identify distinct patterns in radiological images. Therefore, we sought to determine whether radiomic analysis improves the identification of NRS plaques. METHODS AND RESULTS: From 2674 patients referred to coronary computed tomographic angiography caused by stable chest pain, expert readers identified 30 patients with NRS plaques and matched these with 30 non-NRS plaques with similar degree of calcification, luminal obstruction, localization, and imaging parameters...
December 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29228056/back-and-neck-pain-and-function-in-females-with-adolescent-idiopathic-scoliosis-a-follow-up-at-least-23-years-after-conservative-treatment-with-a-milwaukee-brace
#17
Ewa Misterska, Jakub Głowacki, Adam Okręt, Maria Laurentowska, Maciej Głowacki
We aimed to explore the long-term outcomes of back and neck pain and functionality in adult females with adolescent idiopathic scoliosis (AIS), who had been treated with a Milwaukee brace, in a follow-up study a minimum of 23 years after the completion of the treatment, using radiological, clinical and socio-demographical data. Thirty AIS patients (scoliosis group-SG), were included in the study based on an extensive search of Pediatric Orthopedics and Traumatology Clinic charts. All treatments were successfully completed between 1974 and 1990...
2017: PloS One
https://www.readbyqxmd.com/read/29225790/update-on-ventilator-associated-pneumonia
#18
REVIEW
Jean-Francois Timsit, Wafa Esaied, Mathilde Neuville, Lila Bouadma, Bruno Mourvllier
Ventilator-associated pneumonia (VAP) is the most frequent life-threatening nosocomial infection in intensive care units. The diagnostic is difficult because radiological and clinical signs are inaccurate and could be associated with various respiratory diseases. The concept of infection-related ventilator-associated complication has been proposed as a surrogate of VAP to be used as a benchmark indicator of quality of care. Indeed, bundles of prevention measures are effective in decreasing the VAP rate. In case of VAP suspicion, respiratory secretions must be collected for bacteriological secretions before any new antimicrobials...
2017: F1000Research
https://www.readbyqxmd.com/read/29219887/short-term-automated-quantification-of-radiologic-changes-in-the-characterization-of-idiopathic-pulmonary-fibrosis-versus-nonspecific-interstitial-pneumonia-and-prediction-of-long-term-survival
#19
Federica De Giacomi, Sushravya Raghunath, Ronald Karwoski, Brian J Bartholmai, Teng Moua
PURPOSE: Fibrotic interstitial lung diseases presenting with nonspecific and overlapping radiologic findings may be difficult to diagnose without surgical biopsy. We hypothesized that baseline quantifiable radiologic features and their short-term interval change may be predictive of underlying histologic diagnosis as well as long-term survival in idiopathic pulmonary fibrosis (IPF) presenting without honeycombing versus nonspecific interstitial pneumonia (NSIP). MATERIALS AND METHODS: Forty biopsy-confirmed IPF and 20 biopsy-confirmed NSIP patients with available high-resolution chest computed tomography 4 to 24 months apart were studied...
December 6, 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/29198424/the-uterine-fibroid-myoma-tumour-analysis-of-the-global-research-architecture-using-density-equalizing-mapping
#20
Dörthe Brüggmann, Frank Louwen, Tatjana Braun, Doris Klingelhöfer, Jan Bauer, Michael H Bendels, Matthias Bundschuh, David Quarcoo, Jenny Jaque, Eileen M Wanke, David A Groneberg
Uterine fibroids can severely impact a woman's quality of life, result in significant morbidity and are a leading indication for hysterectomy. Many aspects of the disease remain largely obscure. Despite these knowledge gaps, no detailed maps of the global fibroid research architecture have yet been generated. This study used the NewQIS approach to assess worldwide research productivity, encompassing numerous aspects of the scientific output, quality and socioeconomic features. Regression analysis indicated an increase in fibroid research activity in the investigated time periods...
November 15, 2017: Reproductive Biomedicine Online
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