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https://www.readbyqxmd.com/read/28226188/effects-of-melatonin-on-seedling-growth-mineral-nutrition-and-nitrogen-metabolism-in-cucumber-under-nitrate-stress
#1
Ruimin Zhang, Yunkuo Sun, Zeyu Liu, Wen Jin, Yan Sun
In China, excessive use of nitrogen fertilizers in greenhouses leads to nitrate accumulations in soil and plants, which then limits productivity. Melatonin, an evolutionarily highly conserved molecule, has a wide range of functions in plants. We analyzed the effects of melatonin pretreatment on the growth, mineral nutrition, and nitrogen metabolism in cucumber (Cucumis sativus L. 'Jin You No. 1') when seedlings were exposed to nitrate stress. An application of 0.1 mM melatonin significantly improved the growth of plants and reduced their susceptibility to damage due to high nitrate levels (0...
February 22, 2017: Journal of Pineal Research
https://www.readbyqxmd.com/read/28225482/a-case-report-of-posterior-reversible-encephalopathy-syndrome-in-a-patient-receiving-gemcitabine-and-cisplatin
#2
Hannah Cherniawsky, Neesha Merchant, Micheal Sawyer, Maria Ho
RATIONALE: Posterior reversible encephalopathy syndrome (PRES) is a subacute syndrome causing characteristic neurologic and radiologic findings. PRES is predominantly caused by malignant hypertension though it has been associated with immunosuppressive treatments such as chemotherapy. PATIENT CONCERNS: We describe a case of a 58 year old female who developed fluctuant level of consciousness, agitation. DIAGNOSIS: MRI findings were in keeping with posterior reversible encephalopathy syndrome following cycle 6 of palliative gemcitabine and cisplatin therapy for metastatic cholangiocarcinoma...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28225126/carborane-layered-double-hydroxide-nanohybrids-for-potential-targeted-and-magnetically-targeted-bnct-applications
#3
Ahmet Nedim Ay, Hande Akar, Adnana Zaulet, Clara Viňas, Francesc Teixidor, Birgul Zumreoglu-Karan
Carborane-intercalated layered double hydroxide nanohybrids (CB-LDH) and a magnesium ferrite (MF) supported-CB-LDH core-shell nanocomposite (CB-LDH@MF) are reported. The preparation of nanohybrids were carried out by exchanging the interlayer nitrate groups of Mg-Al-NO3-LDH with monothiol-o-carborane (SCB), 1-methyl-2-carboxyl-o-carborane (MeCB), 1-phenyl-2-carboxyl-o-carborane (PhCB) and 1,12-dicarboxyl-p-carborane (COOHCB) molecules. A magnetic core-shell nanocomposite was further prepared by supporting the COOHCB-LDH nanohybrid on MF nanoparticles...
February 22, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28224192/serum-magnesium-and-the-risk-of-prediabetes-a-population-based-cohort-study
#4
Brenda C T Kieboom, Symen Ligthart, Abbas Dehghan, Steef Kurstjens, Jeroen H F de Baaij, Oscar H Franco, Albert Hofman, Robert Zietse, Bruno H Stricker, Ewout J Hoorn
AIMS/HYPOTHESIS: Previous studies have found an association between serum magnesium and incident diabetes; however, this association may be due to reverse causation, whereby diabetes may induce urinary magnesium loss. In contrast, in prediabetes (defined as impaired fasting glucose), serum glucose levels are below the threshold for urinary magnesium wasting and, hence, unlikely to influence serum magnesium levels. Thus, to study the directionality of the association between serum magnesium levels and diabetes, we investigated its association with prediabetes...
February 21, 2017: Diabetologia
https://www.readbyqxmd.com/read/28224159/rice-bran-constituents-immunomodulatory-and-therapeutic-activities
#5
REVIEW
Ho-Young Park, Kwang-Won Lee, Hee-Don Choi
Rice bran, one of the most abundant and valuable byproducts produced during the rice milling process, is of steadily growing interest in recent years due to its potential health benefits. Evidence is rapidly accumulating for the beneficial effects of nutraceuticals. However, the potential benefits of rice bran are found in several of its bioactive ingredients including oils, polysaccharides, proteins, and micronutrients. In addition, a significant advantage of rice bran is that it contains more than 100 antioxidants and several categories of bioactive phytonutrients, such as polyphenols, phytosterols, tocotrienols, γ-oryzanol, B vitamins, minerals, and trace minerals...
February 22, 2017: Food & Function
https://www.readbyqxmd.com/read/28223869/compatibility-study-of-paracetamol-chlorpheniramine-maleate-and-phenylephrine-hydrochloride-in-physical-mixtures
#6
G G G de Oliveira, A Feitosa, K Loureiro, A R Fernandes, E B Souto, P Severino
Paracetamol (PAR), phenylephrine hydrochloride (PHE) and chlorpheniramine maleate (CPM) are commonly used in clinical practice as antipyretic and analgesic drugs to ameliorate pain and fever in cold and flu conditions. The present work describes the use of thermal analysis for the characterization of the physicochemical compatibility between drugs and excipients during the development of solid dosage forms. Thermogravimetric analysis (TGA) and Differential Scanning Calorimetry (DSC) were used to study the thermal stability of the drug and of the physical mixture (drug/excipients) in solid binary mixtures (1:1)...
January 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28223849/review-about-gabapentin-misuse-interactions-contraindications-and-side-effects
#7
REVIEW
Gabriel C Quintero
The current work is targeted to review the risks of gabapentin misuse, its potential interactions with other drugs, side effects and use contraindications. This review consists of a total of 99 biographical references (from the year 1983 to 2016). A publication search of PubMed was performed from January 1983 to December 2016. It included animal studies, clinical studies, case studies and reviews related to gabapentin misuse, potential interactions, side effects and use contraindications. The search terms were gabapentin, anticonvulsant and antiepileptic...
2017: Journal of Experimental Pharmacology
https://www.readbyqxmd.com/read/28223552/ca-mg-zn-co3-and-ca-mg-co3-tri-and-bi-elemental-carbonate-microparticles-for-novel-injectable-self-gelling-hydrogel-microparticle-composites-for-tissue-regeneration
#8
Timothy E L Douglas, Katarzyna Sobczyk, Agata Lapa, Katarzyna Wlodarczyk, Gilles Brackman, Irina Vidiasheva, Katarzyna Reczyńska, Krzysztof Pietryga, David Schaubroeck, Vitaliy Bliznuk, Pascal Van der Voort, Heidi Declercq, Jan Van den Bulcke, Sangram Samal, Dmitry Khalenkow, Bogdan Parakhonskiy, Joris Van Acker, Tom Coenye, Malgorzata Lewandowska-Szumiel, Elzbieta Pamula, Andre Skirtach
Injectable composites for tissue regeneration can be developed by dispersion of inorganic microparticles and cells in a hydrogel phase. In this study, multifunctional carbonate microparticles containing different amounts of calcium, magnesium and zinc were mixed with solutions of gellan gum (GG), an anionic polysaccharide, to form injectable hydrogel-microparticle composites, containing Zn, Ca and Mg. Zn and Ca were incorporated into microparticle preparations to a greater extent than Mg. Microparticle groups were heterogeneous and contained microparticles of differing shape and elemental composition...
February 22, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28222929/magnesium-an-overlooked-electrolyte
#9
Jaya Kala, Ala Abudayyeh
BACKGROUND: Hypermagnesemia is rare and usually iatrogenic. Due to decreased renal function, older patients are generally more susceptible to hypermagnesemia than are younger patients. Because it is not one of the commonly assessed electrolytes in the blood work panel of patients, high levels are usually missed. CASE REPORT: An elderly gentleman with history of leukemia presented with complaints of shortness of breath and extreme weakness while walking. He was diagnosed with severe hypermagnesemia, but unfortunately succumbed to cardiorespiratory arrest...
February 17, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28222767/knockdown-of-slc41a1-magnesium-transporter-promotes-mineralization-and-attenuates-magnesium-inhibition-during-osteogenesis-of-mesenchymal-stromal-cells
#10
Yu-Tzu Tsao, Ya-Yi Shih, Yu-An Liu, Yi-Shiuan Liu, Oscar K Lee
BACKGROUND: Magnesium is essential for numerous physiological functions. Magnesium exists mostly in bone and the amount is dynamically regulated by skeletal remodeling. Accelerating bone mass loss occurs when magnesium intake is insufficient; whereas high magnesium could lead to mineralization defects. However, the underlying magnesium regulatory mechanisms remain elusive. In the present study, we investigated the effects of high extracellular magnesium concentration on osteogenic differentiation of mesenchymal stromal/stem cells (MSCs) and the role of magnesium transporter SLC41A1 in the mineralization process...
February 21, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28222697/magnesium-sulphate-attenuate-remifentanil-induced-postoperative-hyperalgesia-via-regulating-tyrosine-phosphorylation-of-the-nr2b-subunit-of-the-nmda-receptor-in-the-spinal-cord
#11
Jiehao Sun, Hai Lin, Guodong He, Wendong Lin, Jianping Yang
BACKGROUND: Remifentanil induced hyperalgesia (RIH) is characterized by stimulation evoked pain including allodynia and thermal hyperalgesia after remifentanil infusion. N-methyl-D-aspartate (NMDA) receptor was reported to be involved in the progress of RIH. We hypothesized that intrathecal MgSO4 could relieve hyperalgesia after remifentanil infusion via regulating phosphorylation of NMDA receptor NR2B subunit activity in this study. METHODS: Thirty two rats were randomly allocated into control group, model of RIH group, RIH plus 100ug MgSO4 group, RIH plus 300ug MgSO4 group...
February 21, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28222407/parathyroid-hormone-response-to-severe-vitamin-d-deficiency-is-associated-with-femoral-neck-bone-mineral-density-an-observational-study-of-405-women-with-hip-fracture
#12
Marco Di Monaco, Carlotta Castiglioni, Rosa Tappero
OBJECTIVE: Hip-fracture patients with vitamin D deficiency can have either secondary hyperparathyroidism or normal levels of parathyroid hormone (PTH). We hypothesized that bone mineral density (BMD) could be lower in patients with high PTH levels than in those with normal levels of PTH, irrespectively of the severity of vitamin D depletion. DESIGN: In this cross-sectional study, we examined 405 women who had serum 25-hydroxyvitamin D below 12ng/ml 20.0 ± 5.9 (mean ± SD) days after a hip-fracture...
October 2016: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28221876/effect-of-magnesium-acetate-on-the-antimold-activity-of-lactobacillus
#13
Katarzyna Kycia, Anna Bzducha-Wróbel, Karolina Kraśniewska, Anna Chlebowska-Śmigiel, Małgorzata Gniewosz
The antimold activity of lactic acid bacteria (LAB) is used in food biopreservation. The aim of this study was to evaluate the effect of magnesium acetate added to de Man Rogosa Sharpe (MRS) medium on the antimold activity of three LAB strains ( Lactobacillus plantarum , Lactobacillus brevis , and Lactobacillus fermentum ) against molds contaminating food ( Aspergillus oryzae , Aspergillus niger , Penicillium chrysogenum , Fusarium avenaceum , and Rhizopus arrhizus ) and their ability to produce organic acids (acetic acid, lactic acid, and phenyllactic acid)...
January 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28221141/-etiopathogenic-factors-of-the-different-types-of-urinary-litiasis
#14
Miguel Arrabal-Martín, María Carmen Cano-García, Miguel Ángel Arrabal-Polo, Alejandro Domínguez-Amillo, Nelson Canales-Casco, Javier de la Torre-Trillo, José Manuel Cózar-Olmo
In this review, we analyze the etiopathogenic principles of urinary lithiasis formation. In the kidney, calcifications that may cause renal lithiasis are produced as a consequence of processes that injury the urothelium at the papilla and Bellini's ducts. With the improvement of imaging techniques, mainly micro CT scan, it is possible to detect them and we may be able to anticipate to the formation of lithiasis. As we well know, there are different factors that influence the formation of the calculi depending on their composition...
January 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28219433/several-grain-dietary-patterns-are-associated-with-better-diet-quality-and-improved-shortfall-nutrient-intakes-in-us-children-and-adolescents-a-study-focusing-on-the-2015-2020-dietary-guidelines-for-americans
#15
Yanni Papanikolaou, Julie Miller Jones, Victor L Fulgoni
BACKGROUND: The present study identified the most commonly consumed grain food patterns in US children and adolescents (2-18 years-old; N = 8,367) relative to those not consuming grains and compared diet quality and nutrient intakes, with focus on 2015-2020 Dietary Guidelines for Americans (2015-2020 DGA) shortfall nutrients. METHODS: Cluster analysis using data from the National Health and Nutrition Examination Survey 2005-2010, identified 8 unique grain food patterns: a) no consumption of main grain groups, b) cakes, cookies and pies, c) yeast bread and rolls, d) cereals, e) pasta, cooked cereals and rice, f) crackers and salty snacks, g) pancakes, waffles and French toast and other grains, and h) quick breads...
February 20, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28218661/exploring-the-effect-of-lactium%C3%A2-and-zizyphus-complex-on-sleep-quality-a-double-blind-randomized-placebo-controlled-trial
#16
Andrew Scholey, Sarah Benson, Amy Gibbs, Naomi Perry, Jerome Sarris, Greg Murray
Acute, non-clinical insomnia is not uncommon. Sufferers commonly turn to short-term use of herbal supplements to alleviate the symptoms. This placebo-controlled, double-blind study investigated the efficacy of LZComplex3 (lactium™, Zizyphus, Humulus lupulus, magnesium and vitamin B6), in otherwise healthy adults with mild insomnia. After a 7-day single-blind placebo run-in, eligible volunteers (n = 171) were randomized (1:1) to receive daily treatment for 2 weeks with LZComplex3 or placebo. Results revealed that sleep quality measured by change in Pittsburgh Sleep Quality Index (PSQI) score improved in both the LZComplex3 and placebo groups...
February 17, 2017: Nutrients
https://www.readbyqxmd.com/read/28218527/bioactive-peptides-isolated-from-casein-phosphopeptides-enhance-calcium-and-magnesium-uptake-in-caco-2-cell-monolayers
#17
Yong Cao, Jian-Yin Miao, Guo Liu, Zhen Luo, Zumeng Xia, Fei Liu, Mingfei Yao, Xiaoqiong Cao, Shengwei Sun, Yanyin Lin, Yaqi Lan, Hang Xiao
The ability of casein phosphopeptides (CPPs) to bind and transport minerals has been previously studied. However, the single bioactive peptides responsible for the effects of CPPs have not been identified. This study was to purify calcium-binding peptides from CPPs and to determine their effects on calcium and magnesium uptake by Caco-2 cell monolayers. Five monomer peptides designated P1 to P5 were isolated and the amino acid sequences were determined using LC-MS/MS. Compared with the CPP-free control, all five monomeric peptides exhibited significant enhancing effects on the uptake of calcium and magnesium (P < 0...
February 20, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28218524/general-fabrication-of-boride-carbide-and-nitride-nanocrystals-via-a-metal-hydrolysis-assisted-process
#18
Ling Zhou, Lishan Yang, Li Shao, Bo Chen, Fanhui Meng, Yitai Qian, Liqiang Xu
Metal boride, carbide, and nitride materials are useful owing to their wide variety of interesting chemical and physical properties. However, the synthesis of these materials with nano or mesoscale sizes is challenging due to the usually required high temperatures and long reaction durations. To our knowledge, the exploration of a number of simultaneous chemical reactions through rapid synthesis still remains a great challenge. In this study, a general route for the reduction and transformation of metal oxides into related metal boride (TiB2, MoB2, DyB4, ErB4, YB4, LaB6, CeB6, SmB6, EuB6), carbide (SiC, TiC, VC, WC, W2C, ZrC, MoC, NbC), and nitride (TiN, VN, BN, AlN, CrN, MgSiN2) nanocrystals were achieved at 150 °C...
February 20, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28218507/enabling-inkjet-printed-graphene-for-ion-selective-electrodes-with-post-print-thermal-annealing
#19
Qing He, Suprem R Das, Nathaniel T Garland, Dapeng Jing, John A Hondred, Allison A Cargill, Shaowei Ding, Chandran Karunakaran, Jonathan C Claussen
Inkjet printed graphene (IPG) has recently shown tremendous promise in reducing the cost and complexity of graphene circuit fabrication. Herein we demonstrate, for the first time, the fabrication of an ion selective electrode (ISE) with IPG. A thermal annealing process in a nitrogen ambient environment converts the IPG into a highly conductive electrode (sheet resistance changes from 52.8 ± 7.4 MΩ/☐ for unannealed graphene to 172.7 ± 33.3Ω/☐ for graphene annealed at 950°C). Raman spectroscopy and field emission scanning electron microscopy (FESEM) analysis reveals that the printed graphene flakes begin to smooth at an annealing temperature of 500°C and then become more porous and more electrically conductive when annealed at temperatures of 650°C and above...
February 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28218351/the-role-of-ionized-calcium-and-magnesium-in-regional-citrate-anticoagulation-and-its-impact-on-inflammatory-parameters
#20
Karin Strobl, Stephan Harm, Viktoria Weber, Jens Hartmann
INTRODUCTION: Regional anticoagulation with citrate has been found to be superior to heparin in terms of biocompatibility, and numerous protocols for regional citrate anticoagulation have been published, while a consensus on the target concentration of ionized calcium (Ca2+) in the extracorporeal circuit has not been reached so far. METHODS: The aim of this in vitro study was to assess the impact of different citrate concentrations on coagulation as well as on complement activation and cytokine secretion and to investigate the impact of ionized magnesium (Mg2+) on these parameters...
February 13, 2017: International Journal of Artificial Organs
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