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https://www.readbyqxmd.com/read/28717912/management-of-the-open-abdomen-after-liver-transplantation
#1
Christian Hobeika, Marc-Antoine Allard, Petru-Octav Bucur, Salima Naili, Antonio Sa Cunha, Daniel Cherqui, Denis Castaing, René Adam, Eric Vibert
INTRODUCTION: The optimal management of the open abdomen (OA) after liver transplantation (LT) is unclear. The negative pressure wound therapy (NPWT) has been shown to be safe and can increase the chance for early fascial closure in trauma or septic patients. However, little data are available on the specific setting of LT. We aimed to report our experience of OA after LT, marked by the recent use of NPWT. METHODS: All patients with postponed wall closure after LT, from 2002 to 2014, in a single institution were included and retrospectively analyzed...
July 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28667199/predicting-death-over-8-years-in-a-prospective-cohort-of-hiv-infected-women-the-women-s-interagency-hiv-study
#2
Deborah R Gustafson, Qiuhu Shi, Susan Holman, Howard Minkoff, Mardge H Cohen, Michael W Plankey, Richard Havlik, Anjali Sharma, Stephen Gange, Monica Gandhi, Joel Milam, Donald R Hoover
OBJECTIVES: Predicting mortality in middle-aged HIV-infected (HIV+) women on antiretroviral therapies (ART) is important for understanding the impact of HIV infection. Several health indices have been used to predict mortality in women with HIV infection. We evaluated: (1) an HIV biological index, Veterans Aging Cohort Study (VACS); (2) a physical index, Fried Frailty Index (FFI); and (3) a mental health index, Center for Epidemiologic Studies-Depression (CES-D). Proportional hazards regression analyses were used to predict death and included relevant covariates...
June 30, 2017: BMJ Open
https://www.readbyqxmd.com/read/28630851/vacuum-assisted-closure-in-patients-with-post-operative-infections-after-instrumented-spine-surgery-a-series-of-12-cases
#3
Maya Kale, Pravin Padalkar, Varshil Mehta
INTRODUCTION: Post-operative wound infections after spinal surgery is a very serious problem, leading to a risk of significant morbidity which may even lead to prolonged hospitalization. Various treatment protocols have been recommended for debridement, antibiotic, and soft-tissue management, but with mixed results. However, the risk of morbidity is still high with these treatment options. Vacuum-assisted closure (VAC) system has been gaining popularity recently in the management of subacute, acute, and chronic wounds...
January 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28566587/the-superiority-of-vonoprazan-based-first-line-triple-therapy-with-clarithromycin-a-prospective-multi-center-cohort-study-on-helicobacter-pylori-eradication
#4
Soichiro Sue, Hirofumi Kuwashima, Yuri Iwata, Hiroyuki Oka, Isao Arima, Takehide Fukuchi, Katsuyuki Sanga, Yasuhiro Inokuchi, Yuniba Ishii, Masatomo Kanno, Masahiro Terada, Hitoshi Amano, Makoto Naito, Shigeru Iwase, Hiroshi Okazaki, Kazuto Komatsu, Atsushi Kokawa, Ichiro Kawana, Manabu Morimoto, Toshifumi Saito, Yosuke Kunishi, Akihiko Ikeda, Daisuke Takahashi, Haruo Miwa, Tomohiko Sasaki, Toshihide Tamura, Masaaki Kondo, Wataru Shibata, Shin Maeda
Objective We evaluated the safety and efficacy of vonoprazan-based amoxicillin and clarithromycin 7-day triple therapy (VAC) in comparison to proton pump inhibitor (PPI)-based (PAC) as a first-line treatment and vonoprazan-based amoxicillin and metronidazole 7-day triple therapy (VAM) in comparison to PPI-based (PAM) as a second-line treatment for the eradication of Helicobacter pylori in Japan. Methods We performed a non-randomized, multi-center, parallel-group study to compare first-line VAC to PAC and second-line VAM to PAM...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28548706/45-gy-is-not-sufficient-radiotherapy-dose-for-group-iii-orbital-embryonal-rhabdomyosarcoma-after-less-than-complete-response-to-12-weeks-of-arst0331-chemotherapy-a-report-from-the-soft-tissue-sarcoma-committee-of-the-children-s-oncology-group
#5
Ralph P Ermoian, John Breneman, David O Walterhouse, Yueh-Yun Chi, Jane Meza, James Anderson, Douglas S Hawkins, Andrea A Hayes-Jordan, David M Parham, Torunn I Yock, Sarah S Donaldson, Suzanne L Wolden
BACKGROUND: Recent Children's Oncology Group (COG) trials tested the efficacy of reduced therapy in an effort to lessen late effects compared to the Intergroup Rhabdomyosarcoma Study (IRS) IV regimen with associated hematologic and hepatic toxicity, and infertility. Here, we analyze the efficacy of 45 Gray (Gy) local radiotherapy (RT) in patients with Group III orbital embryonal rhabdomyosarcoma (ERMS) enrolled on the COG low-risk study ARST0331. PROCEDURE: Sixty-two patients with Group III orbital ERMS were treated on ARST0331 with four cycles of vincristine (VCR), dactinomycin (DACT), and cyclophosphamide (CPM; VAC, total cumulative CPM dose 4...
May 26, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28541897/capacitive-micro-machined-ultrasound-transducers-for-interstitial-high-intensity-ultrasound-therapies
#6
W Apoutou N'Djin, Bjoern Gerold, Jeremy Vion, Michael Canney, An Nguyen-Dinh, Alexandre Carpentier, Jean-Yves Chapelon
Capacitive Micro-machined Ultrasound Transducers (CMUTs) exhibit several potential advantages over conventional piezo technologies for use in therapeutic ultrasound devices, including: ease of miniaturization and integration with electronics, broad bandwidth (>several MHz), and compatibility with magnetic resonance imaging (MRI). In this work, the electro-acoustic performance of CMUTs designed for interstitial high intensity contact ultrasound (HICU) applications was evaluated and the feasibility of generating ultrasound-induced heating and thermal destruction of biological tissues was studied...
May 24, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28460201/deep-sternal-wound-infections-a-severe-complication-after-cardiac-surgery
#7
A Morgante, F Romeo
Sternal Wound Infections (SWI) represent a dangerous complication after cardiac surgery entailing significantly longer hospital stays and worse short-term survival, especially in case of deep infections (DSWI) with the onset of osteomielitis or mediastinitis. The real incidence of SWI can be estimated between 0.25% and 10%; among the risk factors for sternal dehiscences after a longitudinal median sternotomy, several experiences underline the role of diabetes as an independent risk factor for post-operative infections, especially in patients affected by COPD with higher BMI...
January 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/28427404/retraction-note-evaluation-of-low-cost-custom-made-vac-therapy-compared-with-conventional-wound-dressings-in-the-treatment-of-non-healing-lower-limb-ulcers-in-lower-socio-economic-group-patients-of-kashmir-valley
#8
Zameer Ali, Afshan Anjum, Lubna Khurshid, Hamayun Ahad, Saheel Maajid, Shabir Ahmad Dhar
No abstract text is available yet for this article.
April 20, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28396234/intraoral-vacuum-assisted-closure-therapy-a-pilot-study-in-medication-related-osteonecrosis-of-the-jaw
#9
Johannes Laimer, Otto Steinmassl, Martin Hechenberger, Michael Rasse, Rajmond Pikula, Emanuel Bruckmoser
PURPOSE: For approximately 2 decades, vacuum-assisted closure (VAC) therapy has been widely used for the management of complex wounds and soft tissue defects on the external surface of the body. As yet, this technique has not been studied for intraoral wound management. Therefore, this study evaluated the feasibility, safety, and effectiveness of intraoral VAC therapy in patients with medication-related osteonecrosis of the jaw (MRONJ). PATIENTS AND METHODS: After successful construction of an intraoral device providing sufficient airtight sealing, individually manufactured appliances were used in a prospective clinical trial of 3 patients using the VAC therapy system...
March 18, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28391076/improvised-vacuum-assisted-closure-for-severe-neck-infection-in-poorly-equipped-conditions
#10
S Adam, H D Sama, C Chossegros, M K Bouassalo, M Y Akpoto, E Kpemissi
INTRODUCTION: Dental infections are common and are mainly due to dental caries. When left untreated, these infections can lead to severe life-threatening sepsis. CASE REPORT: The authors reported a case of a severe odontogenic deep neck space infection in a 54-year-old male. The patient was a heavy smoker with incidentally discovered diabetes. He was successfully treated by surgical drainage combined with an improvised Vacuum-Assisted Closure (VAC) system. The results of surgical drainage followed by insertion of an improvised VAC system were spectacular...
April 6, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28345371/ewma-document-negative-pressure-wound-therapy
#11
Jan Apelqvist, Christian Willy, Ann-Mari Fagerdahl, Marco Fraccalvieri, Malin Malmsjö, Alberto Piaggesi, Astrid Probst, Peter Vowden
1. Introduction Since its introduction in clinical practice in the early 1990's negative pressure wounds therapy (NPWT) has become widely used in the management of complex wounds in both inpatient and outpatient care.(1) NPWT has been described as a effective treatment for wounds of many different aetiologies(2,3) and suggested as a gold standard for treatment of wounds such as open abdominal wounds,(4-6) dehisced sternal wounds following cardiac surgery(7,8) and as a valuable agent in complex non-healing wounds...
March 1, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28331276/an-easy-technique-for-negative-pressure-wound-therapy-for-extremities-using-collagen-powder-and-sterile-gloves
#12
L S Sreelesh, P Laxminarayan Bhandari
Negative-pressure wound therapy (NPWT) has become the standard of care for wound management. Application of NPWT to the hand and foot is technically challenging due to difficulty in obtaining a proper air seal. The cost of the treatment is another negative factor affecting NPWT in developing countries. We describe an easy and economical technique for the application of NPWT to the extremities using collage powder and sterile surgical glove. Collagen creates a physiological interface between the wound surface and the environment and is also non-immunogenic, non-pyrogenic, hypoallergenic, and pain-free...
February 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/28280658/cost-effective-alternative-for-negative-pressure-wound-therapy
#13
Jeff J Kim, Mieczyslawa Franczyk, Lawrence J Gottlieb, David H Song
BACKGROUND: Current predominantly used equipments for negative-pressure wound therapy (NPWT) are expensive. In current healthcare climate continually emphasizing cost containment, importance in developing more cost-effective alternatives cannot be understated. Previously, therapeutically equivalent methods of providing NPWT was demonstrated using just low-cost, universally available supplies, coined Gauze-SUCtion (GSUC). Here, we examine long-term potential financial savings of utilizing GSUC over commercialized products...
February 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28256293/use-of-a-home-vacuum-assisted-closure-device-in-the-burn-population-is-both-cost-effective-and-efficacious
#14
Oren P Mushin, Jarrod T Bogue, Mica D Esquenazi, Nicole Toscano, Derek E Bell
INTRODUCTION: The vacuum assisted closure device (VAC) improves wound-healing when utilized as a bolster to secure split thickness skin grafts (STSG). Patients typically remain hospitalized for VAC therapy; however, home VACs (hVAC) are now available. Limited studies examine burns treated with hVAC as a STSG bolster. METHOD: A retrospective study of records from an ABA verified regional burn center was conducted over 23 months. Patients included STSGs for burn. Data points included demographics, burn mechanism and location, graft characteristics, hospital length of stay (LOS), and time to heal...
February 27, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28249233/vac-therapy-with-long-term-continuous-saline-infusion-for-secondary-septic-peritonitis-a-new-strategy-for-the-reduction-of-perioperative-risks
#15
Fulvio Nisi, Federico Marturano, Eleonora Natali, Antonio Galzerano, Patrizia Ricci, Vito Aldo Peduto
BACKGROUND: The management of a septic peritonitis open abdomen is a serious problem for clinicians. Open surgery is associated with several complications such as bleeding and perforation of the bowel. CASE PRESENTATION: The authors report a case of a 59-years-old female who underwent a sigmoid resection with an latero-terminal (L-T) anastomosis for the perforation of a diverticulum. After a few days the patients developed a new widespread peritonitis. At the emergency re-laparotomy, surgeons found dehiscence of the posterior wall of the anastomosis with fecal contamination...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28211936/reduction-of-cyclophosphamide-dose-for-patients-with-subset-2-low-risk-rhabdomyosarcoma-is-associated-with-an-increased-risk-of-recurrence-a-report-from-the-soft-tissue-sarcoma-committee-of-the-children-s-oncology-group
#16
David O Walterhouse, Alberto S Pappo, Jane L Meza, John C Breneman, Andrea Hayes-Jordan, David M Parham, Timothy P Cripe, James R Anderson, William H Meyer, Douglas S Hawkins
BACKGROUND: Failure-free survival (FFS) and overall survival (OS) rates were found to improve on Intergroup Rhabdomyosarcoma Study (IRS) IV (IRS-IV) compared with IRS-III for patients with subset 2 (IRS stage 1, group III nonorbit or stage 3, group I/II) low-risk embryonal rhabdomyosarcoma with the addition of cyclophosphamide (total cumulative cyclophosphamide dose of 26.4 g/m(2) ) to the combination of vincristine and dactinomycin (VAC). The goal of Children's Oncology Group ARST0331 for subset 2 low-risk patients was to reduce the total cumulative cyclophosphamide dose without compromising FFS...
February 17, 2017: Cancer
https://www.readbyqxmd.com/read/28210943/faces-of-frailty-in-aging-with-hiv-infection
#17
REVIEW
Marion Thurn, Deborah R Gustafson
PURPOSE OF THE REVIEW: The number of adults who are aging successfully and have HIV infection is increasing. More effective antiretroviral therapy (ART) regimens are preventing individuals infected with HIV from reaching end stages of the HIV infection and developing AIDS (acquired immunodeficiency syndrome). However, even at lower viral loads, chronic HIV infection appears to have consequences on aging processes, including the development of frailty. RECENT FINDINGS: Frailty is a term used to describe vulnerability in aging...
February 2017: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/28202371/negative-pressure-wound-therapy-an-update
#18
Ahmed Hassan El-Sabbagh
PURPOSE: To get the maximum benefit of vacuum-assisted closure (VAC) in the management of acute and chronic wounds without abuse or misuse. METHODS: Fourty one patients were included in the study. Among them, 9 patients had chronic wounds and the rest 32 patients had acute wounds. In acute wounds, 19 patients had co-morbid conditions. Seven patients had gaped wounds, 4 patients had necrotizing fasciitis and 2 patients had enterocutaneous fistula. RESULTS: The hospitalization period varied from 1 to 6 weeks...
April 2017: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/28198150/the-effectiveness-of-negative-pressure-therapy-on-infected-wounds-preliminary-results
#19
Federico Lo Torto, Marco Ruggiero, Paola Parisi, Zachary Borab, Manuel Sergi, Bruno Carlesimo
Vacuum-assisted closure (VAC) therapy is a sophisticated system that maintains a closed, humid, sterile and isolated environment. Wound infection is considered a relative contraindication. The objective of this study is to extend the indications for VAC therapy to include infected wounds by demonstrating its ability to increase the antibiotic concentration in the damaged and infected tissues. Patients who presented with ulcers infected with daptomycin-sensitive bacteria were eligible to be enrolled in this prospective study...
February 15, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28050534/the-use-of-negative-pressure-wound-therapy-in-the-treatment-of-infected-wounds-case-studies
#20
Daniel de Alcântara Jones, Wilson Vasconcelos Neves Filho, Janice de Souza Guimarães, Daniel de Araújo Castro, Antonio Marcos Ferracini
OBJECTIVE: To evaluate the results and benefits obtained from the topical use of negative pressure wound therapy (NPWT) in patients with infected wounds. METHODS: This was a retrospective study of 20 patients (17 males and three females, mean age 42 years) with infected wounds treated using NPWT. The infected wounds were caused by trauma. The treatment system used was VAC.(®) (Vacuum Assisted Closure, KCI, San Antonio, United States) applied to the wound in continuous mode from 100 to 125 mmHg...
November 2016: Revista Brasileira de Ortopedia
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