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https://www.readbyqxmd.com/read/29660388/outcomes-of-gracilis-muscle-flaps-in-the-management-of-groin-complications-after-arterial-bypass-with-prosthetic-graft
#1
Anahita Dua, Vy T Ho, Christina Rao, Sapan S Desai
INTRODUCTION: This study details two-year outcomes of a modified gracilis muscle flap (GMF) technique in providing tissue coverage for groin complications after arterial bypass surgery with synthetic graft. METHODS: All patients who developed groin infections after lower extremity arterial bypass with synthetic graft that underwent a GMF were included from June 2014 to March 2017 from a prospectively collected, purpose-built institutional database. Modifications to the standard technique included identification of the muscle using ultrasound to ensure precise skip incisions, preservation of the segmental blood supply, widening of the tunnel through which the muscle is retroflexed, placement of a wound VAC for healing, and lifelong antibiotics...
April 13, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29600578/successful-treatment-of-enteroatmospheric-fistulas-in-combination-with-negative-pressure-wound-therapy-experience-on-3-cases-and-literature-review
#2
Ulrich Wirth, Bernhard W Renz, Dorian Andrade, Tobias S Schiergens, Helmut Arbogast, Joachim Andrassy, Jens Werner
Enteroatmospheric fistulas (EAF) are rare but challenging and morbid complications of abdominal surgery and require time- as well as resource-consuming management. Furthermore, they severely affect patients' quality of life. Several treatment modalities for EAF management are described in the literature. We describe 3 consecutive cases of EAF treatment by employing negative pressure wound therapy (NPWT) along with either a special silicone fistula adapter or a Silo-Vac-like system in another case to isolate the fistula from the remaining abdominal wound...
March 30, 2018: International Wound Journal
https://www.readbyqxmd.com/read/29595535/-jelly-vac-for-negative-pressure-therapy-for-complex-wound-closure-a-report-of-two-cases
#3
Patrick F Bergin, Jason R Wild, Timothy G Weber
CASE: A 35-year-old man sustained an open calcaneal fracture with bone loss, and a 57-year-old woman sustained an avulsion of the entirety of the plantar skin. Both patients were treated with multiple debridements and soft-tissue coverage. "Jelly-VAC" (vacuum-assisted closure) therapy was used after each debridement and during the soft-tissue coverage. CONCLUSION: Jelly-VAC therapy is a promising alternative that allows negative-pressure therapy with the use of ultrasound jelly to prevent air leakage into the wound...
January 2018: JBJS Case Connector
https://www.readbyqxmd.com/read/29563372/the-effect-of-ultrasound-assisted-debridement-combined-with-vacuum-pump-therapy-in-deep-sternal-wound-infections
#4
Lachmandath Tewarie, Nikolay Chernigov, Andreas Goetzenich, Ajay Moza, Rüdiger Autschbach, Rashad Zayat
PURPOSE: To assess whether a combined treatment of low-frequency (25 kHz) ultrasonic-debridement systems followed by vacuum-assisted wound closure (VAC) produces a better outcome in deep sternal wound infections (SWIs) compared to that of VAC alone. METHODS: We evaluated 45 consecutive patients (25 males) between January 2013 and December 2016, in whom deep SWI was treated with a combination of low-frequency ultrasonic debridement system followed by vacuum-assisted closure (group A, n = 23) or with only vacuum-assisted closure therapy (group B, n = 22)...
March 22, 2018: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29541566/surgical-interventions-for-advanced-parameningeal-rhabdomyosarcoma-of-children-and-adolescents
#5
REVIEW
Paul J Choi, Joe Iwanaga, R Shane Tubbs, Emre Yilmaz
Owing to its rarity, rhabdomyosarcoma of the head and neck (HNRMS) has seldom been discussed in the literature. As most of the data is based only on the retrospective experiences of tertiary healthcare centers, there are difficulties in formulating a standard treatment protocol. Moreover, the disease is poorly understood at its pathological, genetic, and molecular levels. For instance, 20% of all histological assessment is inaccurate; even an experienced pathologist can confuse rhabdomyosarcoma (RMS) with neuroblastoma, Ewing's sarcoma, and lymphoma...
January 9, 2018: Curēus
https://www.readbyqxmd.com/read/29527250/temporary-abdominal-closure-combined-with-an-irrigating-system-utilizing-hypochlorous-acid-solution-to-decrease-abdominal-mucopurulence
#6
Marc R Matthews, Asia N Quan, Alexandra S Weir, Kevin N Foster, Daniel M Caruso
Introduction: Leaving the abdominal cavity open is a well-described and frequently utilized technique in the treatment of severe intra-abdominal sepsis. Irrigation through a negative pressure wound therapy device is a technique employed to assist in the closure of wounds as well as the reduction of bacterial contamination. Furthermore, hypochlorous acid has been found to be safe and effective in microorganismal elimination from extremity wounds. There is no literature regarding the infusion of hypochlorous solution into the abdominal cavity for intra-abdominal sepsis or mucopurulent abscesses or biofilm...
2018: Eplasty
https://www.readbyqxmd.com/read/29515846/on-the-feasibility-of-the-computational-modelling-of-the-endoluminal-vacuum-assisted-closure-of-an-oesophageal-anastomotic-leakage
#7
Ester Comellas, Facundo J Bellomo, Iván Rosales, Luis F Del Castillo, Ricardo Sánchez, Pau Turon, Sergio Oller
Endoluminal vacuum-assisted closure (E-VAC) is a promising therapy to treat anastomotic leakages of the oesophagus and bowel which are associated with high morbidity and mortality rates. An open-pore polyurethane foam is introduced into the leakage cavity and connected to a device that applies a suction pressure to accelerate the closure of the defect. Computational analysis of this healing process can advance our understanding of the biomechanical mechanisms at play. To this aim, we use a dual-stage finite-element analysis in which (i) the structural problem addresses the cavity reduction caused by the suction and (ii) a new constitutive formulation models tissue healing via permanent deformations coupled to a stiffness increase...
February 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29481377/management-of-early-deep-wound-infection-after-thoracolumbar-instrumentation-continuous-irrigation-suction-system-versus-vacuum-assisted-closure-system
#8
Wei Yuan, Xuan Liu, Xiaoshu Zhou, Lei Pei, Yue Zhu
STUDY DESIGN: A retrospective study. OBJECTIVE: To compare the clinical outcomes of continues irrigation suction systems (CISS) or vacuum assisted closure system (VACS) in early deep wound infection (DWI) after thoracolumbar instrumentation. SUMMARY OF BACKGROUND DATA: DWI after thoracolumbar instrumentation is challenging and debridement followed by either CISS or VACS has been proven to be effective. So far which one of the system has more advantages over the other remains unclear...
February 23, 2018: Spine
https://www.readbyqxmd.com/read/29460403/effects-of-ivabradine-on-endothelial-function-aortic-properties-and-ventricular-arterial-coupling-in-chronic-systolic-heart-failure-patients
#9
Ivano Bonadei, Edoardo Sciatti, Enrico Vizzardi, Davide Fabbricatore, Mattia Pagnoni, Laura Rossi, Valentina Carubelli, Carlo M Lombardi, Marco Metra
AIM: Heart rate (HR) is an important prognostic factor in patients affected by chronic heart failure (CHF); ivabradine has been demonstrated to significantly reduce nonfatal myocardial infarction and hospitalization rate for acute heart failure and to improve left ventricular (LV) reverse remodeling, quality of life, exercise capacity, and arterial elastance (Ea) in these patients. We aimed at evaluating the short-term effects of ivabradine on ventricular-arterial coupling (VAC), aortic stiffness, and endothelial function in stable patients with CHF...
February 20, 2018: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/29457605/negative-pressure-therapy-in-the-regeneration-of-the-sciatic-nerve-using-vacuum-assisted-closure-in-a-rabbit-model
#10
Jian-Ping Wu, Zhen-Huan Jiang, Xiao-Jun Feng, Jian-Nong Jiang, Mao-Hua Cheng
BACKGROUND The aim of this study was to investigate the effects of negative pressure therapy in the regeneration of the rabbit sciatic nerve using vacuum assisted closure (VAC). MATERIAL AND METHODS Thirty male New Zealand white rabbits underwent surgical injury of the sciatic nerve, followed by negative pressure therapy using vacuum assisted closure (VAC), in three treatment groups: Group A: 0 kPa; Group B: -20 kPa; Group C: -40 kPa. At 12 weeks following surgery, the following factors were studied: motor nerve conduction velocity (MNCV); the number of myelinated nerve fibers; the wet weight of the gastrocnemius muscle...
February 19, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29372375/endoluminal-vacuum-therapy-e-vac-a-treatment-option-in-oesophagogastric-surgery
#11
D J Pournaras, R H Hardwick, P M Safranek, V Sujendran, J Bennett, G D Macaulay, A Hindmarsh
BACKGROUND: Leaks from the upper gastrointestinal tract often pose a management challenge, particularly when surgical treatment has failed or is impossible. Vacuum therapy has revolutionised the treatment of wounds, and its role in enabling and accelerating healing is now explored in oesophagogastric surgery. METHODS: A piece of open cell foam is sutured around the distal end of a nasogastric tube using a silk suture. Under general anaesthetic, the foam covered tip is placed endoscopically through the perforation and into any extra-luminal cavity...
January 25, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29319719/a-new-low-cost-negative-pressure-wound-therapy-versus-a-commercially-available-therapy-device-widely-used-to-treat-complex-traumatic-injuries-a-prospective-randomized-non-inferiority-trial
#12
Fabio Kamamoto, Ana Lucia Munhoz Lima, Marcelo Rosa de Rezende, Rames Mattar-Junior, Marcos de Camargo Leonhardt, Kodi Edson Kojima, Carla Chineze Dos Santos
OBJECTIVES: Negative-pressure wound therapy has been widely adopted to reduce the complexity of treating a broad range of acute and chronic wounds. However, its cost is high. The objective of this study was to evaluate the following two different methods of negative-pressure wound therapy in terms of healing time: a low-cost method of negative-pressure wound therapy (a pressure stabilizer device connected to a hospital wall-vacuum system with a gauze-sealed dressing, USP) and the standard of care (vacuum-assisted closure, VAC)...
December 2017: Clinics
https://www.readbyqxmd.com/read/29280702/effective-management-of-extensive-tissue-loss-after-abdominoperineal-resection-for-buschke-loewenstein-tumor
#13
G Balducci, G Carbotta, M G Sederino, A Delvecchio, R Laforgia, P Sallustio, P Lobascio, F Ferrarese, M Minafra, S Fedele, N Palasciano
The giant condyloma acuminatum or Buschke-Loewenstein tumor is a rare, sexually transmitted disease. It is an epithelial tumor characterized by its high potential of malignancy towards developing into a highly invasive squamous cell carcinoma. The present case concerns a drug addicted 40-year-old man who smuggled drugs using his rectum. He had a partially ulcerated mass in the perianal area of about 20 x 10 cm. He reported a progressive growth of this neoplasm during the last 3 years associated with perianal pain, obstructed defecation, bad sitting posture, no fever and weight loss...
September 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29231172/cefazolin-and-coagulation-disorders-a-case-report
#14
Eugénie Gay, Anne Barthel, Nicolas Rouzic, Basile Henriot, Baptiste Quélennec, Aurélien Lorleac'h, Nathalie Prades, François Schmitt
We report the case of a 79-year-old patient, admitted to the department of infectious diseases at Bretagne Sud Hospital Center for a right calcaneal osteitis, complicated by a pacemaker leads infectious endocarditis. Meticillin sensitive Staphylococcus aureus was documented by blood culture. Antibiotic treatment was established using intravenous cefazolin for an initial 6 weeks period. Prothrombin time (PT) decreased as well as vitamin K dependent factors, without anticoagulation therapy, at day 7 of cefazolin treatment...
January 1, 2018: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/29228443/postoperative-deep-wound-dehiscence-of-thoracotomy-with-isolation-of-corynebacterium-tuberculostearicum-surgical-site-infection-or-colonization
#15
A Tampakis, E C Tampaki, K Kontzoglou, E Patsouris, G Kouraklis, D Lardinois
OBJECTIVE: Infections with Corynebacterium tuberculostearicum are very rare as in most of the cases its isolation is associated with tissue colonization rather than infection. CASE REPORT: An 80-year old female patient was sent to the consultation hour of thoracic surgery for evaluation of a symptomatic persistent unilateral pleural effusion of her right lung. The differential diagnosis included either the presence of a chronic pleural empyema or the presence of malignancy...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29218673/results-of-endoscopic-vacuum-assisted-closure-device-for-treatment-of-upper-gi-leaks
#16
Marc Bludau, Hans F Fuchs, Till Herbold, Martin K H Maus, Hakan Alakus, Felix Popp, Jessica M Leers, Christiane J Bruns, Arnulf H Hölscher, Wolfgang Schröder, Seung-Hun Chon
BACKGROUND: Esophageal perforations and postoperative leakage of esophagogastrostomies are considered to be life-threatening conditions due to the potential development of mediastinitis and consecutive sepsis. Vacuum-assisted closure (VAC) techniques, a well-established treatment method for superficial infected wounds, are based on a negative pressure applied to the wound via a vacuum-sealed sponge. Endoluminal VAC (E-VAC) therapy as a treatment for GI leakages in the rectum was introduced in 2008...
April 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29124073/first-necrotizing-fasciitis-caused-by-haemophilus-influenza-serotype-a
#17
Giang T Quach, Jared Frisby, Kurt Kralovich, Mustafa Bohra
Necrotizing fasciitis (NF) is an infrequently encountered skin infection that has high morbidity and mortality, even with prompt medical and surgical intervention. We describe the case of a 67-year-old male presenting with significant NF in his left lower extremity, despite aggressive surgical intervention, and included multiple surgical debridements, ACell Matrix, split-thickness, and negative wound VAC therapy. Ultimately, this patient required a below the knee amputation. This is the first documented case of Haemophilus influenza type a causing NF...
October 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/29046458/a-tyrosine-based-trafficking-motif-of-the-tegument-protein-pul71-is-crucial-for-human-cytomegalovirus-secondary-envelopment
#18
Andrea N Dietz, Clarissa Villinger, Stefan Becker, Manfred Frick, Jens von Einem
The human cytomegalovirus (HCMV) tegument protein pUL71 is required for efficient secondary envelopment and accumulates at the Golgi compartment-derived viral assembly complex (vAC) during infection. Analysis of various C-terminally truncated pUL71 proteins fused to enhanced green fluorescent protein (eGFP) identified amino acids 23 to 34 as important determinants for its Golgi complex localization. Sequence analysis and mutational verification revealed the presence of an N-terminal tyrosine-based trafficking motif (YXXΦ) in pUL71...
January 1, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29034563/heart-failure-study-of-multipoint-pacing-effects-on-ventriculoarterial-coupling-rationale-and-design-of-the-humvee-trial
#19
Christina Chrysohoou, Polychronis Dilaveris, Christos-Konstantinos Antoniou, Ioannis Skiadas, Konstantinos Konstantinou, Konstantinos Gatzoulis, Ioannis Kallikazaros, Dimitrios Tousoulis
Cardiac resynchronization therapy (CRT) is an established therapy for symptomatic heart failure (HF). Unfortunately, many recipients remain nonresponders. Studies have revealed the potential role of multipoint pacing (MPP) in improving response and outcomes. The aim of this study is to compare the effects of MPP against those of standard biventricular pacing (BVP) on (i) ventriculoarterial coupling (VAC) and energy efficiency of the failing heart, (ii) diastolic function, (iii) quality of life, and (iv) NT-proBNP levels and glomerular filtration rate (GFR) during a follow-up of 13 months...
October 15, 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29019713/modified-endoscopic-vacuum-therapy-for-nonhealing-esophageal-anastomotic-leak-technique-description-and-review-of-literature
#20
Guy Pines, Ilan Bar, Amir Elami, Shimon Sapojnikov, Ofir Hikri, Dennis Ton, Bruce Mosenkis, Ehud Melzer
BACKGROUND: Endoscopic vacuum-assisted closure (EVAC) therapy is increasingly being used as a new promising method for repairing upper gastrointestinal defects of different etiologies with high success rates. EVAC therapy consists of placing a sponge either within the lumen or within an abscess cavity connected with a nasogastric (NG) tube to a negative pressure system, thus decreasing bacterial contamination and edema and promoting granulation tissue proliferation, thereby gradually decreasing the cavity size until complete closure...
January 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
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