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https://www.readbyqxmd.com/read/28900587/prevalence-and-predictors-of-depression-amongst-hypertensive-individuals-in-karachi-pakistan
#1
Samar Mahmood, Syeda Z Hassan, Muqadus Tabraze, Mohammad O Khan, Iqra Javed, Ameer Ahmed, Omer M Siddiqui, Mehek Narmeen, Maham J Ahmed, Afreen Tariq, Mustafa S Patel, Kaneez Fatima
OBJECTIVE: While studies evaluating the prevalence of depression and hypertension have been extensively carried out in high income countries, there is a paucity of information assessing the prevalence of depression within hypertensive patients in low income nations. The primary objective of this study was to investigate the prevalence of undiagnosed depression in hypertensive patients within a tertiary care facility in Karachi, Pakistan. The secondary objective was to assess factors associated with undiagnosed depression in this group...
June 26, 2017: Curēus
https://www.readbyqxmd.com/read/28862406/double-blind-randomized-controlled-clinical-trial-of-nacl-chitosan-3-vs-nacl-on-high-blood-pressure-parameters-of-healthy-volunteers-with-pre-hypertension-characterized-by-a-systolic-blood-pressure-between-130-mmhg-and-140-mmhg
#2
François-André Allaert
BACKGROUND: Because of the impressive increase in the risk of cardiovascular complications associated with levels of BP previously considered to be normal, the JNC 7 report has introduced a new classification that includes the term "prehypertension" for those with BPs ranging from 120-139 mmHg systolic and/or 80-89 mmHg diastolic. In the framework of a salt reduction as recommended by health authorities, this trial evaluates if the use of Symbiosal® reduces more prehypertension than standard table marine salt (NaCl)...
August 31, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/28828478/association-of-jnc-8-and-sprint-systolic-blood-pressure-levels-with-cognitive-function-and-related-racial-disparity
#3
Ihab Hajjar, Kristine J Rosenberger, Ambar Kulshreshtha, Hilsa N Ayonayon, Kristine Yaffe, Felicia C Goldstein
Importance: The Eighth Joint National Committee (JNC-8) recommended treating systolic blood pressure (SBP) to a target below 150 mm Hg in older adults, whereas data from the Systolic Blood Pressure Intervention Trial (SPRINT) suggested that a SBP level of lower than 120 mm Hg decreases cardiovascular event rates. Target SBP guidelines have not addressed the potential that black patients may have greater morbidity and mortality from hypertension, especially with regard to cognitive outcomes...
October 1, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28822507/prevalence-and-incidence-of-hypertension-results-from-a-representative-cohort-of-over-16-000-adults-in-three-cities-of-south-asia
#4
Dorairaj Prabhakaran, Panniyammakal Jeemon, Shreeparna Ghosh, Roopa Shivashankar, Vamadevan S Ajay, Dimple Kondal, Ruby Gupta, Mohammed K Ali, Deepa Mohan, Viswanathan Mohan, Masood M Kadir, Nikhil Tandon, Kolli Srinath Reddy, K M Venkat Narayan
BACKGROUND: Despite high projected burden, hypertension incidence data are lacking in South Asian population. We measured hypertension prevalence and incidence in the Center for cArdio-metabolic Risk Reduction in South Asia (CARRS) adult cohort. METHODS: The CARRS Study recruited representative samples of Chennai, Delhi, and Karachi in 2010/11, and socio-demographic and risk factor data were obtained using a standard common protocol. Blood pressure (BP) was measured in the sitting position using electronic sphygmomanometer both at baseline and two year follow-up...
July 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28658794/a-comparative-study-on-clinical-and-biochemical-parameters-in-amlodipine-and-cilnidipine-treated-hypertensive-patients
#5
Kiran Shetty, Ranjan Shetty, Lakshminarayana Bairy, Pragna Rao, Amruth Kiran, Manjunath Shetty, Deepak, Vidya Nayak
INTRODUCTION: Hypertension is a major health issue worldwide. Calcium Channel Blockers (CCBs) are the most commonly used antihypertensive agents. CCBs act on voltage-dependent calcium channels and they were categorized into two subclasses, Dihydropyridine (DHP) and non-Dihydropyridine (non-DHP) derivative. Amlodipine is a third generation L-type of DHP and Cilnidipine is a novel L/N-type of DHP CCB, both drugs have excellent pharmacological profiles with the unique actions. AIM: To study the clinical and biochemical profile in Amlodipine and Cilnidipine treated mild to moderate hypertensive patients...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28525818/hypertension-update-jnc8-and-beyond
#6
REVIEW
Tara Shrout, David W Rudy, Michael T Piascik
Hypertension is the most preventable major risk factor for cardiovascular morbidity and mortality. The etiology of elevated blood pressure is a complex process involving the interaction of genetics, demographics, comorbid disorders, and environmental influences. Effective hypertensive therapy has been shown to reduce cardiovascular morbidity and mortality. JNC reports have served as a valuable source of guidelines, and JNC 8 is the most recently updated guideline for the prevention, diagnosis, and treatment of hypertension...
April 2017: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/28099585/impact-of-different-normality-thresholds-for-24-hour-abpm-at-the-primary-health-care-level
#7
Guilherme Brasil Grezzana, David William Moraes, Airton Tetelbon Stein, Lucia Campos Pellanda
Background: Hypertension is an important risk factor for cardiovascular outcomes. Primary health care (PHC) physicians should be prepared to act appropriately in the prevention of cardiovascular risk factors. However, the rates of patients with control of blood pressure (BP) remain low. The impact of the reclassification of high BP by 24-hour ambulatory BP monitoring (ABPM) can lead to different medical decisions in PHC. Objective: To evaluate the agreement between the BP measured by a conventional method by PHC physicians and by 24-hour ABPM, considering different BP normal thresholds for the 24-hour ABPM according to the V Brazilian ABPM Guidelines and the European Society of Hypertension Guidelines...
February 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28070471/importance-of-mean-red-cell-distribution-width-in-hypertensive-patients
#8
Ahmed Bilal, Junaid H Farooq, Immad Kiani, Salman Assad, Haider Ghazanfar, Imran Ahmed
PURPOSE: Red cell distribution width (RDW), expressed in femtoliters (fl), is a measure of the variation in the size of circulating erythrocytes and is often expressed as a direct measurement of the width of the distribution. We aim to observe the mean value of red cell distribution width (RDW) in hypertensive patients. Increased RDW can be used as a tool for early diagnosis, as an inflammatory marker, and a mortality indicator in hypertensive patients due to its close relation to inflammation...
November 29, 2016: Curēus
https://www.readbyqxmd.com/read/28033742/assessment-of-achieved-systolic-blood-pressure-in-newly-treated-hypertensive-patients-aged-60-79-years-before-and-after-eighth-joint-national-committee-recommendations
#9
RANDOMIZED CONTROLLED TRIAL
Michael S Kelly, Joseph J Saseen, Joel C Marrs
OBJECTIVE: To determine whether patients who were newly prescribed antihypertensive therapy after the Eighth Joint National Committee (JNC 8) update were treated to a relaxed systolic blood pressure (SBP) goal compared with patients treated before the update. METHODS: A retrospective cohort study approved by the Colorado Multiple Institutional Review Board. Patients aged 60-79 years, without diabetes or chronic kidney disease (CKD), newly treated for hypertension at a University of Colorado primary care clinics were included...
February 2017: Therapeutic Advances in Cardiovascular Disease
https://www.readbyqxmd.com/read/28019714/a-prospective-study-of-the-association-between-total-sleep-duration-and-incident-hypertension
#10
Dhananjay Yadav, Dae Sung Hyun, Song Vogue Ahn, Sang-Baek Koh, Jang Young Kim
The aim of this prospective study was to evaluate total sleep duration as a potential risk factor for the development of hypertension after a mean of 2.6 years of follow-up. The study participants comprised 1715 Korean adults aged 40 to 70 years. The participants were without hypertension at baseline (2005-2008) and during follow-up (2008-2011) to determine the incident cases of hypertension. Based on a self-reported questionnaire, the individuals were stratified according to total sleep duration (<6 hours, 6-7...
May 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/27957711/the-role-of-beta-blockers-in-the-treatment-of-hypertension
#11
John M Cruickshank
IMPORTANCE: Two major guide-line committees (JNC-8 and NICE UK) have dropped beta-blockers as first-line therapy in the treatment of hypertension. Also, recent meta-analyses (that do not take age into account) have concluded that beta-blockers are inappropriate first-line agents in the treatment of hypertension. This review seeks to shed some light on the "rights and wrongs" of such actions and conclusions. OBJECTIVES: Because the pathophysiology of primary/essential hypertension differs in elderly and younger subjects, the latter being closely linked to obesity and increased sympathetic nerve activity, the author sought to clarify the efficacy of beta-blockers in the younger/middle-aged group in reducing the risk of death, and cardiovascular end-points...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27899129/a-community-based-study-on-prevalence-and-correlates-of-erectile-dysfunction-among-kinondoni-district-residents-dar-es-salaam-tanzania
#12
Pedro Pallangyo, Paulina Nicholaus, Peter Kisenge, Henry Mayala, Noel Swai, Mohamed Janabi
BACKGROUND: Globally, erectile dysfunction burden (ED) is rising appreciably and it is projected to affect about 332 million men by the year 2025. This rise is attributable to the rising incidence of conditions associated with ED including obesity, diabetes, hypertension, coronary artery disease and depression. We conducted this community-based screening to elucidate on the prevalence of ED and its associated factors among men residing in an urban community in Tanzania. METHODS: We conducted a cross-sectional community-based study and interviewed 441 men aged at least 18 years...
November 29, 2016: Reproductive Health
https://www.readbyqxmd.com/read/27856202/total-antihypertensive-therapeutic-intensity-score-and-its-relationship-to-blood-pressure-reduction
#13
Phillip D Levy, Robina Josiah Willock, Michael Burla, Aaron Brody, James Mahn, Alexander Marinica, Samar A Nasser, John M Flack
Predicting blood pressure (BP) response to antihypertensive therapy is challenging. The therapeutic intensity score (TIS) is a summary measure that accounts for the number of medications and the relative doses a patient received, but its relationship to BP change and its utility as a method to project dosing equivalence has not been reported. We conducted a prospective, single center, randomized controlled trial to compare the effects of Joint National Committee (JNC) 7 compliant treatment with more intensive (<120/80 mm Hg) BP goals on left ventricular structure and function in hypertensive patients with echocardiographically determined subclinical heart disease who were treated over a 12-month period...
December 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27754180/ed-08-4-diagnosis-and-treatment-of-hypertensive-emergency-in-children
#14
Lin Shi
According to the seventh report of Joint National Committee (JNC 7), hypertensive emergency (HE), a kind of hypertensive crisis, is defined as a sudden and abrupt elevation in blood pressure so as to cause acute target organ dysfunctions, including central nervous system, cardiovascular system or kidneys. Patients with HE require immediate reduction in markedly elevated blood pressure. Currently, there are no international guidelines for children HE, so the JNC definition is commonly used. Hypertensive emergency in children is rare but a life-threatening emergency...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754110/os-22-06-evaluating-the-health-related-quality-of-life-of-hypertensive-patients
#15
Mansi Patil, Manoj Durairaj, Syed Mohammed Tauseef
OBJECTIVE: To evaluate and assess the health related quality of life (HRQOL) of hypertensive patients in West India using the MINCHAL scale and WHO-BREF questionnaire. DESIGN AND METHOD: 500 male hypertensives (age group 20-60 years) that were on anti-hypertensive treatment for minimum six months were chosen for a cross-sectional study. They were divided into 3 categories of hypertension according to the JNC-7 classification i.e., Stage 1 and Stage 2 as "uncontrolled" hypertension and pre-hypertensive as "controlled" hypertension...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754095/os-20-09-diagnosis-and-treatment-of-cognitive-disorders-in-arterial-hypertension
#16
Viktoria Krotova, Tatyana Khomazyuk
OBJECTIVE: One of the first disorders of affection subcortical brain structures in arterial hypertension (AH) is a decrease in mental processes, intellectual rigidity. To investigate the cognitive disorders (CD) in AH patients 1-2 stages of working age and the effectiveness of nootropic agent (phenibutum) and anticholinergic drug (ipidacrinum) in combined antihypertensive therapy. DESIGN AND METHOD: Observed 60 patients with controlled AH 1-2 stages and CD. The median age-55,3 ± 9,1 years and duration of AH-10,2 ± 5,8 years...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754018/js-ksh-jsh-chl-01-1-cardio-metabolic-risks-in-hypertension-are-we-different-from-western-societies
#17
Hiroshi Itoh
Many hypertension guidelines have been published mainly from Western countries to standardize the management of hypertension all over the world, however, the significance of hypertension, along with other cardio-metabolic risks, such as obesity, diabetes or dyslipidemia should differ among different races. This paper compares the relevance of hypertension, one of the most important cardio-metabolic risk factors, in Asian and Western societies.1) Low target level of blood pressure control for diabetic hypertensives in JapanIn the Japanese Society of Hypertension Guidelines for the management of Hypertension (JSH2014), the target of blood pressure (BP) control in hypertensive patients with diabetes was set as < 130/80 mmHg...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754001/db-02-3-strict-control-of-hypertension-in-the-elderly-with-diabetes-and-chronic-kidney-disease-pro
#18
Lawrence Appel
The identification of explicit blood pressure targets for clinical management remains controversial, particularly in older individuals with co-morbidities. Recommendations from the panel appointed to the Eighth Joint National Committee (JNC 8) and results of the SPRINT trial have rekindled interest in this issue. JNC8 recommended a higher (more relaxed) BP goal of < 150/90, instead of the traditional BP goal of <140/90, in persons aged 60+. In contrast, the recently completed SPRINT trial, which enrolled high risk patients without diabetes, documented that a lower (more stringent) SBP goal of <120 mmHg reduced total mortality and cardiovascular disease events compared to <140 mmHg...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27734656/cilnidipine-next-generation-calcium-channel-blocker
#19
Mukesh Madhukar Shete
Hypertension is one of the most common conditions seen in primary care and a major public health problem in India. It can lead to various complications if not detected early and treated appropriately. As per the latest Eighth Joint National Committee (JNC 8) the goal BP in most hypertensive patients age <60 years should be <140/90 mmHg and treatment can be started by selecting drugs from among 4 specific medication classes i.e. angiotensin converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB), calcium channel blocker (CCB) or diuretics...
April 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27678289/the-relationship-between-cognitive-functioning-and-the-jnc-8-guidelines-for-hypertension-in-older-adults
#20
Felicia C Goldstein, Ihab M Hajjar, Callie B Dunn, Allan I Levey, Whitney Wharton
BACKGROUND: Guidelines for hypertension treatment by the Eighth Joint National Committee (JNC-8) in 2014 recommended a target systolic blood pressure (BP) of <150/<90 mmHg in persons older than 60 years, in contrast to the 2003 JNC-7 recommendations of systolic BP <140 mmHg. This study evaluated the implications of raising the BP target on cognitive functioning and conversion from normal cognition to mild cognitive impairment (MCI). METHODS: This was a longitudinal study of individuals older than 60 years enrolled in the NIH-NIA Alzheimer's Disease Centers...
January 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
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