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https://www.readbyqxmd.com/read/28922727/the-relevance-of-gastric-cancer-biomarkers-in-prognosis-and-pre-and-post-chemotherapy-in-clinical-practice
#1
REVIEW
Muhammad Abbas, Murad Habib, Muhammad Naveed, Kumaragurubaran Karthik, Kuldeep Dhama, Meiqi Shi, Chen Dingding
Gastric cancer (GC) is one among the major cancer types, causing human deaths and present noticeable heterogeneity. The incidences and mortality rates are higher in males in comparison to females with a male to female ratio of 2.3:1. A lot of studies have revealed out the molecular basis, pathogenesis, invasion and metastasis related findings of gastric stomach cancer. Present review encompasses the salient information on various biomarkers for the early diagnosis, treatment and prognosis of gastric cancer elaborate the clinical importance of serum tumor markers in patients with this cancer as well as checking the growths, together with epigenetic changes and genetic polymorphisms...
September 14, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28922625/living-and-dying-with-advanced-dementia-a-prospective-cohort-study-of-symptoms-service-use-and-care-at-the-end-of-life
#2
Elizabeth L Sampson, Bridget Candy, Sarah Davis, Anna Buylova Gola, Jane Harrington, Michael King, Nuriye Kupeli, Gerry Leavey, Kirsten Moore, Irwin Nazareth, Rumana Z Omar, Victoria Vickerstaff, Louise Jones
BACKGROUND: Increasing number of people are dying with advanced dementia. Comfort and quality of life are key goals of care. AIMS: To describe (1) physical and psychological symptoms, (2) health and social care service utilisation and (3) care at end of life in people with advanced dementia. DESIGN: 9-month prospective cohort study. SETTING AND PARTICIPANTS: Greater London, England, people with advanced dementia (Functional Assessment Staging Scale 6e and above) from 14 nursing homes or their own homes...
August 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28922165/the-gastrointestinal-brain-axis-in-humans-as-an-evolutionary-advance-of-the-root-leaf-axis-in-plants-a-hypothesis-linking-quantum-effects-of-light-on-serotonin-and-auxin
#3
Lucio Tonello, Bekim Gashi, Alessandro Scuotto, Glenda Capello, Massimo Cocchi, Fabio Gabrielli, Jack A Tuszynski
Living organisms tend to find viable strategies under ambient conditions that optimize their search for, and utilization of, life-sustaining resources. For plants, a leading role in this process is performed by auxin, a plant hormone that drives morphological development, dynamics, and movement to optimize the absorption of light (through branches and leaves) and chemical "food" (through roots). Similarly to auxin in plants, serotonin seems to play an important role in higher animals, especially humans. Here, it is proposed that morphological and functional similarities between (i) plant leaves and the animal/human brain and (ii) plant roots and the animal/human gastro-intestinal tract have general features in common...
September 15, 2017: Journal of Integrative Neuroscience
https://www.readbyqxmd.com/read/28920138/study-on-the-sediment-characteristics-of-the-snow-in-a-typical-residential-community-and-its-integrated-biological-treatment-pattern-in-harbin
#4
Bin-Xia Xue, Tong-Yu Li, Chun-Ying Li, Li Wei, Xiao-He Hou
Winter cities have severe shortages of water resources. The effective classification and recycling of urban water resources that are available here are therefore significant for the sustainable utilization of water in winter cities, and snow is a potential water resource. In this research, the water quality of the snow and the pollutant composition in the vehicle roads of a typical residential community of Harbin are analyzed. It is concluded that there is a large amount of suspended substances, including chemical oxygen demand (COD), salt, ammonia, and oil in this snow...
September 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28920085/baseline-prescription-and-one-year-persistence-of-secondary-prevention-drugs-after-an-index-stroke-in-central-ghana
#5
Fred Stephen Sarfo, Bruce Ovbiagele, John Akassi, Gloria Kyem
BACKGROUND AND PURPOSE: There is a paucity of data on persistence of secondary prevention medications among stroke survivors in resource-limited settings where stroke is on a rapid upward trajectory and its management severely challenged. To avert new cardiovascular events after stroke, preventive medications should be promptly instituted and used continuously. We report 1-year rates and determinants of persistent utilization of secondary prevention therapies after stroke in Ghana. METHODS: A retrospective observational study involving 418 stroke survivors enrolled into a Neurology clinic in a tertiary institution in central Ghana between January 2011 and December 2013...
March 2017: ENeurologicalSci
https://www.readbyqxmd.com/read/28919292/treatment-patterns-health-care-resource-utilization-and-spending-in-medicaid-beneficiaries-initiating-second-generation-long-acting-injectable-agents-versus-oral-atypical-antipsychotics
#6
Dominic Pilon, Neeta Tandon, Marie-Hélène Lafeuille, Rhiannon Kamstra, Bruno Emond, Patrick Lefebvre, Kruti Joshi
PURPOSE: Second-generation long-acting injectable therapies (SGA-LAIs) may reduce health care resource utilization (HRU) and health care costs compared with daily oral atypical antipsychotics (OAAs) in patients with schizophrenia due to reduced dosing frequency, delivery/monitoring by a health care provider, and improved adherence. The aim of the present study was to compare treatment patterns, HRU, and Medicaid spending in patients with schizophrenia initiated on SGA-LAIs (overall and according to agent) versus OAAs...
September 14, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28919148/creation-and-dissemination-of-a-multispecialty-gme-curriculum-in-pediatric-and-adolescent-gynecology-the-naspag-resident-education-committee-experiences
#7
Carol Wheeler, K J Browner-Elhanan, Yolanda Evans, Nathalie Fleming, Patricia S Huguelet, Nicole W Karjane, Meredith Loveless, Hina J Talib, Paritosh Kaul
OBJECTIVE: The goal was to develop a multispecialty committee to address deficiencies in pediatric and adolescent gynecology resident education through curricular development under the auspices of the North American Society for Pediatric and Adolescent Gynecology. DESIGN: A multispecialty North American committee was organized to develop both short and long curricula in pediatric and adolescent gynecology (PAG) through a combination of conference calls and face-to-face meetings...
September 14, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28917629/decision-making-about-healthcare-related-tests-and-diagnostic-strategies-a-qualitative-study-with-experts-suggests-that-test-accuracy-data-alone-is-rarely-sufficient-for-decision-making
#8
Reem A Mustafa, Wojtek Wiercioch, Matthew Ventresca, Jan Brozek, Holger J Schünemann
OBJECTIVE: To identify the critical factors that determine recommendations and other decisions about health care related tests and diagnostic strategies (HCTDS). METHODS: We used a qualitative descriptive approach and conducted semi-structured in-depth interviews with 24 international experts (informants) in evidence and decisions about HCTDS. RESULTS: Although test accuracy (TA) was the factor most commonly considered by organizations when developing recommendations about HCTDS, informants agreed that TA is necessary but rarely, if ever, sufficient and may be misleading when solely considered...
September 13, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28917176/health-based-ingestion-exposure-guidelines-for-vibrio-cholerae-technical-basis-for-water-reuse-applications
#9
Annetta P Watson, Anthony Q Armstrong, George H White, Brandolyn H Thran
U.S. military and allied contingency operations are increasingly occurring in locations with limited, unstable or compromised fresh water supplies. Non-potable graywater reuse is currently under assessment as a viable means to increase mission sustainability while significantly reducing the resources, logistics and attack vulnerabilities posed by transport of fresh water. Development of health-based (non-potable) exposure guidelines for the potential microbial components of graywater would provide a logical and consistent human-health basis for water reuse strategies...
September 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28917016/predictors-of-outpatient-resource-utilization-following-ventral-and-incisional-hernia-repair
#10
Alex Wade, Margaret A Plymale, Daniel L Davenport, Sara E Johnson, Vashisht V Madabhushi, Erica Mastoroudis, Charlie Tancula, John Scott Roth
INTRODUCTION: Little is known about the predictors of increased ambulatory costs following open ventral and incisional hernia repair (VIHR); however, postoperative complications would be expected to be associated with an increased burden on outpatient resources. The purpose of this study is to evaluate the impact of perioperative factors on outpatient resource utilization following VIHR. METHODS: With IRB approval, the surgery scheduling system was queried to identify all cases of VIHR done at our institution over 3 years...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28916490/decision-making-about-healthcare-related-tests-and-diagnostic-strategies-a-systematic-review-shows-limitations-in-most-tools-designed-to-assess-quality-and-develop-recommendations
#11
Reem A Mustafa, Wojtek Wiercioch, Maicon Falavigna, Yuan Zhang, Liudmila Ivanova, Ingrid Arevalo-Rodriguez, Adrienne Cheung, Barbara Prediger, Matthew Ventresca, Jan Brozek, Nancy Santesso, Patrick Bossuyt, Amit X Garg, Nancy Lloyd, Monika Lelgemann, Diedrich Bühler, Holger J Schünemann
OBJECTIVES: To identify and describe critical appraisal tools designed for assessing the quality of evidence (QoE) and/or strength of recommendations (SoR) related to healthcare related tests and diagnostic strategies (HCTDS). STUDY DESIGN: and Settings: We conducted a systematic review to identify tools applied in guidelines, methodological articles, and systematic reviews to assess HCTDS. RESULTS: We screened 5534 titles and abstracts, 1004 full text articles, and abstracted data from 330 references...
September 12, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28916453/making-the-legal-and-ethical-case-for-universal-screening-for-postpartum-mood-and-anxiety-disorders-in-pediatric-primary-care
#12
Amy Lewis Gilbert, Casey Balio, Nerissa S Bauer
Postpartum depression (PPD), part of a larger spectrum of perinatal mood and anxiety disorders, affects up to 15% of women following the birth of an infant. Fathers may also be affected. PPD not only affects caregivers, but also impacts infants through mechanisms such as inadequate caregiver-infant interactions and non-adherence to safety practices. The negative impact on infants may extend across the life course through adulthood. This article seeks to move the needle toward universal screening for PPD using validated tools in pediatric primary care settings for new caregivers by making the legal and ethical case for this course of action in a manner that is both compelling and accessible for clinicians...
September 12, 2017: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/28915841/is-there-room-for-resilience-a-scoping-review-and-critique-of-substance-use-literature-and-its-utilization-of-the-concept-of-resilience
#13
REVIEW
Katherine Rudzinski, Peggy McDonough, Rosemary Gartner, Carol Strike
Research in the area of illicit substance use remains preoccupied with describing and analyzing the risks of people who use drugs (PWUD), however more recently there has been a drive to use a strengths-based or resilience approach as an alternative to investigating drug use. This leads us to ask: what can be known about PWUD from the point of view of resilience? The objective of this scoping review is to analyze how the concept of resilience is defined, operationalized, and applied in substance use research...
September 15, 2017: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/28915208/appropriate-use-criteria-for-cardiac-computed-tomography-impact-on-diagnostic-utility
#14
Karan Bami, Manuja Premaratne, Jasmine Lamba, Yeung Yam, Alomgir Hossain, Marissa Keenan, Tony Haddad, Saipriya Anand, Ian G Burwash, Terrence D Ruddy, Girish Dwivedi, Benjamin J W Chow
BACKGROUND: Appropriate Use Criteria (AUC) guidelines for cardiac computed tomography (CCT) were developed to limit testing to reasonable clinical settings. However, significant testing is still done for inappropriate indications. This study investigates the impact of AUC on evaluability of CCT to determine if inappropriate tests result in a greater proportion of nondiagnostic results. METHODS: Investigators reviewed the medical records of 2417 consecutive patients who underwent CCT at the University of Ottawa Heart Institute...
September 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28915165/employee-organizational-commitment-and-hospital-performance
#15
Kevin M Baird, Amy Tung, Yanjie Yu
BACKGROUND: There is widespread evidence of the purported benefits of employee organizational commitment (EOC) and its impact on both individual and organizational performance. This study contributes to this literature by providing a unique insight into this relationship, focusing on the interrelationship between EOC with hospital performance and the role of the provision of adequate facilities in eliciting EOC. PURPOSE: The aim of this study was to introduce and empirically examine a new theoretical model in which it is argued that the performance of hospitals with regard to the provision of adequate facilities (medical facilities, support facilities, and staff resources) influences the level of EOC, which in turn influences hospital performance with regard to patient care and operational effectiveness...
September 15, 2017: Health Care Management Review
https://www.readbyqxmd.com/read/28915109/factors-affecting-utilization-of-youth-friendly-health-services-in-lagos-state-nigeria
#16
Toriola Temitope Femi-Adebayo, Yetunde Kuyinu, Olusola Adedeji Adejumo, Olayinka Goodman
Background Youth friendly health services (YFHS) are services that attract, respond to the needs of and retain young people for continuing care. This study was conducted to determine the factors affecting utilization of government (GYFF) and non-governmental youth friendly facilities (NGYFF) in Lagos state, Nigeria. Methods A descriptive cross-sectional study was conducted. A total of 543 adolescents aged 15-24 years, between August 1, 2014 and October 31, 2014 were consecutively recruited from 10 (five government and five non-governmental) youth friendly health facilities that had been in operation for at least 6 months prior to the study...
September 15, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28914803/achieving-congestion-mitigation-using-distributed-power-control-for-spectrum-sensor-nodes-in-sensor-network-aided-cognitive-radio-ad-hoc-networks
#17
Long Zhang, Haitao Xu, Fan Zhuo, Hucai Duan
The data sequence of spectrum sensing results injected from dedicated spectrum sensor nodes (SSNs) and the data traffic from upstream secondary users (SUs) lead to unpredictable data loads in a sensor network-aided cognitive radio ad hoc network (SN-CRN). As a result, network congestion may occur at a SU acting as fusion center when the offered data load exceeds its available capacity, which degrades network performance. In this paper, we present an effective approach to mitigate congestion of bottlenecked SUs via a proposed distributed power control framework for SSNs over a rectangular grid based SN-CRN, aiming to balance resource load and avoid excessive congestion...
September 15, 2017: Sensors
https://www.readbyqxmd.com/read/28914747/appropriate-use-criteria-for-cardiac-computed-tomography-does-computed-tomography-have-incremental-value-in-all-appropriate-use-criteria-categories
#18
Fernanda Erthal, Manuja Premaratne, Yeung Yam, Li Chen, Jasmine Lamba, Marissa Keenan, Tony Haddad, Kishu Pharasi, Saipriya Anand, Rob S Beanlands, Ian G Burwash, Girish Dwivedi, Terrence D Ruddy, Benjamin J W Chow
PURPOSE: Cardiac imaging expenditures have come under scrutiny, and a focus on appropriate use criteria (AUC) has arisen to ensure cost-effective resource utilization. Although AUC has been developed by clinical experts, it has not undergone rigorous quality assurance testing to ensure that inappropriate indications for testing yield little clinical benefit. The objective of the study was to evaluate the potential incremental prognostic value of coronary computed tomographic angiography (CCTA) in the different AUC categories...
September 13, 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28914497/fuel-production-from-seawater-and-fuel-cells-using-seawater
#19
Shunichi Fukuzumi, Yong-Min Lee, Wonwoo Nam
Seawater is the most abundant resource on our planet and fuel production from seawater has the remarkable merit that it would not compete with growing demands of pure water. This review focuses on the production of fuels from seawater and their direct use in fuel cells. Electrolysis of seawater under appropriate conditions affords hydrogen and dioxygen with 100% Faradaic efficiency without oxidation of chloride ion. Photoelectrocatalytic production of hydrogen from seawater provides promising way to produce hydrogen with low cost and high efficiency...
September 15, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28914470/selective-electrochemical-reduction-of-co2-to-ethanol-on-b-and-n-codoped-nanodiamond
#20
Yanming Liu, Yujing Zhang, Kai Chen, Xie Quan, Xinfei Fan, Yan Su, Shuo Chen, Huimin Zhao, Yaobin Zhang, Hongtao Yu, Michael R Hoffmann
Electrochemical reduction of CO2 to ethanol, a clean and renewable liquid fuel with high heating value, is an attractive strategy for global warming mitigation and resource utilization. However, converting CO2 to ethanol remains great challenge due to the low activity, poor product selectivity and stability of electrocatalysts. Here, B and N codoped nanodiamond (BND) was reported as an efficient and stable electrode for selective reduction of CO2 to ethanol. Good ethanol selectivity was achieved on BND with high Faradaic efficiency of 93...
September 15, 2017: Angewandte Chemie
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