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https://www.readbyqxmd.com/read/29139172/association-between-structural-brain-network-efficiency-and-intelligence-increases-during-adolescence
#1
Marinka M G Koenis, Rachel M Brouwer, Suzanne C Swagerman, Inge L C van Soelen, Dorret I Boomsma, Hilleke E Hulshoff Pol
Adolescence represents an important period during which considerable changes in the brain take place, including increases in integrity of white matter bundles, and increasing efficiency of the structural brain network. A more efficient structural brain network has been associated with higher intelligence. Whether development of structural network efficiency is related to intelligence, and if so to which extent genetic and environmental influences are implicated in their association, is not known. In a longitudinal study, we mapped FA-weighted efficiency of the structural brain network in 310 twins and their older siblings at an average age of 10, 13, and 18 years...
November 14, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29132909/a-comprehensive-systematic-review-of-pharmacy-perspectives-on-interprofessional-education-and-collaborative-practice
#2
REVIEW
Alla El-Awaisi, Sundari Joseph, Maguy Saffouh El Hajj, Lesley Diack
INTRODUCTION: Pharmacists are key professionals in the collaborative working process and are integral members of the healthcare team. However, there is paucity of information regarding their perspectives towards interprofessional education (IPE) and collaborative practice. AIMS: The aim of this systematic review is to synthesize, summarise and evaluate the quality of the quantitative and qualitative literature related to the perspectives of pharmacy students, pharmacy faculty and practising pharmacists toward IPE and collaborative practice...
November 2, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29132065/common-components-analysis-an-adapted-approach-for-evaluating-programs
#3
Nicole R Morgan, Kelly D Davis, Cameron Richardson, Daniel F Perkins
Common Components Analysis (CCA) summarizes the results of program evaluations that utilize randomized control trials and have demonstrated effectiveness in improving their intended outcome(s) into their key elements. This area of research has integrated and modified the existing CCA approach to provide a means of evaluating components of programs without a solid evidence-base, across a variety of target outcomes. This adapted CCA approach (a) captures a variety of similar program characteristics to increase the quality of the comparison within components; (b) identifies components from four primary areas (i...
October 12, 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/29131813/mechanical-fatigue-resistance-of-an-implantable-branched-lead-system-for-a-distributed-set-of-longitudinal-intrafascicular-electrodes
#4
A E Pena, S S Kuntaegowdanahalli, J J Abbas, J Patrick, K W Horch, R Jung
OBJECTIVE: A neural interface system has been developed that consists of an implantable stimulator/recorder can with a 15-electrode lead that trifurcates into three bundles of five individual wire longitudinal intrafascicular electrodes. This work evaluated the mechanical fatigue resistance of the branched lead and distributed electrode system under conditions designed to mimic anticipated strain profiles that would be observed after implantation in the human upper arm. APPROACH: Custom test setups and procedures were developed to apply linear or angular strain at four critical stress riser points on the lead and electrode system...
November 13, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29130824/longitudinal-structural-and-functional-differences-between-proportional-and-poor-motor-recovery-after-stroke
#5
Adrian G Guggisberg, Pierre Nicolo, Leonardo G Cohen, Armin Schnider, Ethan R Buch
BACKGROUND: Evolution of motor function during the first months after stroke is stereotypically bifurcated, consisting of either recovery to about 70% of maximum possible improvement ("proportional recovery, PROP") or in little to no improvement ("poor recovery, POOR"). There is currently no evidence that any rehabilitation treatment will prevent POOR and favor PROP. OBJECTIVE: To perform a longitudinal and multimodal assessment of functional and structural changes in brain organization associated with PROP...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29129939/indigenous-migration-dynamics-in-the-ecuadorian-amazon-a-longitudinal-and-hierarchical-analysis
#6
Jason Davis, Samuel Sellers, Clark Gray, Richard Bilsborrow
Amazonian indigenous populations are approaching a critical stage in their history in which increasing education and market integration, rapid population growth and degradation of natural resources threaten the survival of their traditions and livelihoods. A topic that has hardly been touched upon in this context is migration and population mobility. We address this by analysing a unique longitudinal dataset from the Ecuadorian Amazon on the spatial mobility of five indigenous groups and mestizo co-residents...
2017: Journal of Development Studies
https://www.readbyqxmd.com/read/29129195/barriers-to-integrating-the-continuum-of-care-for-opioid-and-alcohol-use-disorders-in-primary-care-a-qualitative-longitudinal-study
#7
Erik D Storholm, Allison J Ober, Sarah B Hunter, Kirsten M Becker, Praise O Iyiewuare, Chau Pham, Katherine E Watkins
Untreated substance use disorders remain a pervasive public health problem in the United States, especially among medically-underserved and low-income populations, with opioid and alcohol use disorders (OAUD) being of particular concern. Primary care is an underutilized resource for delivering treatment for OAUD, but little is known about the organizational capacity of community-based primary care clinics to integrate treatment for OAUD. The objective of this study was to use an organizational capacity framework to examine perceived barriers to implementing the continuum of care for OAUD in a community-based primary care organization over three time points: pre-implementation (preparation), early implementation (practice), and full implementation...
December 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29128508/relative-and-absolute-test-retest-reliabilities-of-biomechanical-risk-factors-for-knee-osteoarthritis-progression-benchmarks-for-meaningful-change
#8
Nicholas M Brisson, Paul W Stratford, Monica R Maly
OBJECTIVE: Biomechanical factors are important treatment targets in knee osteoarthritis. The knee adduction (KAM) and flexion (KFM) moments, quadriceps strength and power, load frequency, and body mass index (BMI) all have the potential to affect knee articular cartilage integrity by modulating forces across the joint. To identify clinically meaningful change, however, these measurements must be reliable and sensitive to change. This study estimated relative and absolute test-retest reliabilities over long periods of biomechanical risk factors for knee osteoarthritis progression...
November 8, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29127911/healthy-minds-from-0-100-years-optimising-the-use-of-european-brain-imaging-cohorts-lifebrain
#9
K B Walhovd, A M Fjell, R Westerhausen, L Nyberg, K P Ebmeier, U Lindenberger, D Bartrés-Faz, W F C Baaré, H R Siebner, R Henson, C A Drevon, G P Knudsen, I Budin-Ljøsne, B W J H Penninx, P Ghisletta, O Rogeberg, L Tyler, L Bertram
The main objective of "Lifebrain" is to identify the determinants of brain, cognitive and mental (BCM) health at different stages of life. By integrating, harmonising and enriching major European neuroimaging studies across the life span, we will merge fine-grained BCM health measures of more than 5,000 individuals. Longitudinal brain imaging, genetic and health data are available for a major part, as well as cognitive and mental health measures for the broader cohorts, exceeding 27,000 examinations in total...
November 8, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29127484/progress-in-developing-transgenic-monkey-model-for-huntington-s-disease
#10
REVIEW
Brooke R Snyder, Anthony W S Chan
Huntington's disease (HD) is a complex neurodegenerative disorder that has no cure. Although treatments can often be given to relieve symptoms, the neuropathology associated with HD cannot be stopped or reversed. HD is characterized by degeneration of the striatum and associated pathways that leads to impairment in motor and cognitive functions as well as psychiatric disturbances. Although cell and rodent models for HD exist, longitudinal study in a transgenic HD nonhuman primate (i.e., rhesus macaque; HD monkeys) shows high similarity in its progression with human patients...
November 10, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29126930/white-matter-integrity-mediates-decline-in-age-related-inhibitory-control
#11
Peipei Li, Angeliki Tsapanou, Razlighi R Qolamreza, Yunglin Gazes
Previous DTI studies have reported associations between white matter integrity and performance on the Stroop interference task. The current study aimed to add to these studies of inhibitory control by investigating how the differences in age and in white matter integrity relate to Stroop performance, and to examine whether the effect of age on Stroop performance is mediated by white matter integrity. 179 healthy adults from 20 to 80 years old were recruited in the study. DTI data were processed through TRACULA and the mean fractional anisotropy (FA) of 18 major white matter tracts were extracted and used for statistical analysis...
November 7, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29126345/integrating-item-accuracy-and-reaction-time-to-improve-the-measurement-of-inhibitory-control-abilities-in-early-childhood
#12
Brooke E Magnus, Michael T Willoughby, Clancy B Blair, Laura J Kuhn
Efforts to improve children's executive function are often hampered by the lack of measures that are optimized for use during the transition from preschool to elementary school. Whereas preschool-based measures often emphasize response accuracy, elementary school-based measures emphasize reaction time (RT)-especially for measures inhibitory control (IC) tasks that typically have a speeded component. The primary objective of this study was to test in a preschool-aged sample whether the joint use of item-level accuracy and RT data resulted in improved scoring for three IC tasks relative to scores derived from accuracy data alone...
November 1, 2017: Assessment
https://www.readbyqxmd.com/read/29126059/enhancing-early-psychosis-treatment-using-smartphone-technology-a-longitudinal-feasibility-and-validity-study
#13
Tara A Niendam, Laura M Tully, Ana-Maria Iosif, Divya Kumar, Kathleen E Nye, Jennifer C Denton, Lauren N Zakskorn, Taylor L Fedechko, Katherine M Pierce
Smartphone applications that promote symptom tracking and self-management may improve treatment of serious mental illness (SMI). Although feasibility has been established in chronic adult outpatient or inpatient SMI samples, no data exist regarding implementation of smartphone technology in adolescent and young adult populations as part of early psychosis (EP) outpatient care. We implemented a smartphone "app" plus clinician Dashboard as an add-on treatment tool in the University of California, Davis Early Psychosis Program...
October 21, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29125694/impaired-long-contact-white-matter-fibers-integrity-is-related-to-depression-in-parkinson-s-disease
#14
Jia-Yong Wu, Yang Zhang, Wen-Bo Wu, Gang Hu, Yun Xu
AIMS: Depression is one of the most common nonmotor symptoms in Parkinson's disease (PD). But the pathogenesis is still unclear. Studies have shown that depression in PD is closely related to the white matter abnormalities, but the number of studies is still very small and lack of whole brain white matter lesions study. METHODS: In this study, we investigated whole brain white matter integrity in 31 depressed PD patients and 37 nondepressed PD patients by diffusion tensor imaging...
November 10, 2017: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/29122811/comparison-of-inappropriate-shocks-and-other-health-outcomes-between-single-and-dual-chamber-implantable-cardioverter-defibrillators-for-primary-prevention-of-sudden-cardiac-death-results-from-the-cardiovascular-research-network-longitudinal-study-of-implantable
#15
Pamela N Peterson, Robert T Greenlee, Alan S Go, David J Magid, Andrea Cassidy-Bushrow, Romel Garcia-Montilla, Karen A Glenn, Jerry H Gurwitz, Stephen C Hammill, John Hayes, Alan Kadish, Kristi Reynolds, Param Sharma, David H Smith, Paul D Varosy, Humberto Vidaillet, Chan X Zeng, Sharon-Lise T Normand, Frederick A Masoudi
BACKGROUND: In US clinical practice, many patients who undergo placement of an implantable cardioverter-defibrillator (ICD) for primary prevention of sudden cardiac death receive dual-chamber devices. The superiority of dual-chamber over single-chamber devices in reducing the risk of inappropriate ICD shocks in clinical practice has not been established. The objective of this study was to compare risk of adverse outcomes, including inappropriate shocks, between single- and dual-chamber ICDs for primary prevention...
November 9, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29122573/cause-specific-life-years-lost-in-people-with-mental-disorders-a-nationwide-register-based-cohort-study
#16
Annette Erlangsen, Per Kragh Andersen, Anita Toender, Thomas Munk Laursen, Merete Nordentoft, Vladimir Canudas-Romo
BACKGROUND: People with mental disorders have higher mortality rates than the general population and more detailed estimates of mortality differences are needed to address this public health issue. We aimed to assess whether differences in cause-specific mortality between people with and without mental disorders have changed between 1995 and 2014 by quantifying life-years lost and assessing differences over time. METHODS: Using a cohort design, we linked nationwide population data from the Danish Civil Registration System to information about hospital contacts from the Psychiatric Central Research Register and deaths from the Danish Cause of Death register...
November 6, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/29121916/a-longitudinal-study-looking-at-and-beyond-care-recipient-health-as-a-predictor-of-long-term-care-home-admission
#17
Raquel S D Betini, John P Hirdes, Donna S Lero, Susan Cadell, Jeff Poss, George Heckman
BACKGROUND: The unpaid care provided by informal caregivers allows care recipients to live longer in their homes, which often results in fewer unnecessary long term care home (LTCH) admissions. Although the relationship between care recipient's health characteristics and institutionalization is well known, the influence of caregiver distress and caregiving coresidence and relationship on this outcome is less clear. This study examines the association of care recipient care needs, caregiver distress and caregiving coresidence and relationship with care recipient long term care home admission...
November 9, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29120940/bilateral-hemispheric-changes-and-language-outcomes-in-chronic-left-hemisphere-stroke
#18
Won Min Lee, Sunghyon Kyeong, Eun Young Park, Hee Seung Yang, Hyunkoo Kang, Dae Hyun Kim
The role of the right hemisphere in recovery of language function after left hemisphere stroke remains unclear. This prospective study aimed to determine the relationship between bilateral hemispheric changes and severity of aphasia in patients with chronic left hemisphere stroke. Twenty-three patients with left hemisphere stroke with aphasia and 10 healthy control patients underwent high-resolution T1-weighted and diffusion tensor imaging. Patients with aphasia were assessed using the Korean version of the Western Aphasia Battery, and severity of aphasia was quantified in terms of aphasia quotient; patients were classified into two groups - the mild-to-moderate and severe groups - on the basis of severity of aphasia...
November 8, 2017: Neuroreport
https://www.readbyqxmd.com/read/29118202/bayesian-optimal-adaptation-explains-age-related-human-sensorimotor-changes
#19
Faisal Karmali, Gregory T Whitman, Richard F Lewis
The brain uses information from different sensory systems to guide motor behavior, and aging is associated with a simultaneous decline in the quality of sensory information provided to the brain and a deterioration in motor control. Correlations between age-dependent decline in sensory anatomical structures and behavior have been demonstrated, and it has recently been suggested that a Bayesian framework could explain these relationships. Here we show that age-dependent changes in a human sensorimotor reflex, the vestibulo-ocular reflex, are explained by a Bayesian optimal adaptation in the brain occurring in response to death of motion-sensing hair cells...
November 8, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29118146/dental-hygiene-students-perceptions-of-importance-and-confidence-in-applying-motivational-interviewing-during-patient-care
#20
Angela Mills, Wendy E Kerschbaum, Philip S Richards, Gail A Czarnecki, Janet S Kinney, Anne E Gwozdek
Purpose: Motivational Interviewing (MI) is an evidence-based, patient-centered counseling approach for eliciting behavior change. In 2012, the University of Michigan (U-M) Dental Hygiene Program significantly enhanced their behavior change curriculum by reinforcing and building upon the Motivational Interviewing segment. The purpose of this study was to examine students' perceptions of the importance of MI and their confidence in applying it during patient care.Methods: A convenience sample of 22 U-M Class of 2015 dental hygiene students who had received an enhanced curriculum participated in this study, utilizing a retrospective, pre-test/post-test design...
February 2017: Journal of Dental Hygiene: JDH
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