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https://www.readbyqxmd.com/read/29346787/speech-and-communication-changes-reported-by-people-with-parkinson-s-disease
#1
Ellika Schalling, Kerstin Johansson, Lena Hartelius
BACKGROUND: Changes in communicative functions are common in Parkinson's disease (PD), but there are only limited data provided by individuals with PD on how these changes are perceived, what their consequences are, and what type of intervention is provided. AIM: To present self-reported information about speech and communication, the impact on communicative participation, and the amount and type of speech-language pathology services received by people with PD. METHODS: Respondents with PD recruited via the Swedish Parkinson's Disease Society filled out a questionnaire accessed via a Web link or provided in a paper version...
January 18, 2018: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/29346651/bipartite-network-analysis-of-gene-sharings-in-the-microbial-world
#2
Eduardo Corel, Raphaël Méheust, Andrew K Watson, James O McInerney, Philippe Lopez, Eric Bapteste
Extensive microbial gene flows affect how we understand virology, microbiology, medical sciences, genetic modification and evolutionary biology. Phylogenies only provide a narrow view of these gene flows: plasmids and viruses, lacking core genes, cannot be attached to cellular life on phylogenetic trees. Yet viruses and plasmids have a major impact on cellular evolution, affecting both the gene content and the dynamics of microbial communities. Using bipartite graphs that connect up to 149,000 clusters of homologous genes with 8217 related and unrelated genomes, we can in particular show patterns of gene sharing that do not map neatly with the organismal phylogeny...
January 15, 2018: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29346579/web-based-cognitive-behavior-therapy-for-chronic-pain-patients-with-aberrant-drug-related-behavior-outcomes-from-a-randomized-controlled-trial
#3
Honoria Guarino, Chunki Fong, Lisa A Marsch, Michelle C Acosta, Cassandra Syckes, Sarah K Moore, Ricardo A Cruciani, Russell K Portenoy, Dennis C Turk, Andrew Rosenblum
Objective: There is high unmet need for effective behavioral treatments for chronic pain patients at risk for or with demonstrated histories of opioid misuse. Despite growing evidence supporting technology-based delivery of self-management interventions for chronic pain, very few such programs target co-occurring chronic pain and aberrant drug-related behavior. This randomized controlled trial evaluated the effectiveness of a novel, web-based self-management intervention, grounded in cognitive behavior therapy, for chronic pain patients with aberrant drug-related behavior...
January 13, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29346510/viper-a-web-application-for-rapid-expert-review-of-variant-calls
#4
Marius Wöste, Martin Dugas
Summary: With the rapid development in next-generation sequencing, cost and time requirements for genomic sequencing are decreasing, enabling applications in many areas such as cancer research. Many tools have been developed to analyze genomic variation ranging from single nucleotide variants to whole chromosomal aberrations. As sequencing throughput increases, the number of variants called by such tools also grows. Often employed manual inspection of such calls is thus becoming a time-consuming procedure...
January 15, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29346446/osteopontin-opn-as-a-csf-and-blood-biomarker-for-multiple-sclerosis-a-systematic-review-and-meta-analysis
#5
Elmira Agah, Arshia Zardoui, Amene Saghazadeh, Mona Ahmadi, Abbas Tafakhori, Nima Rezaei
Identifying a reliable biomarker may accelerate diagnosis of multiple sclerosis (MS) and lead to early management of the disease. Accumulating evidence suggest that cerebrospinal fluid (CSF) and peripheral blood concentration of osteopontin (OPN) may have diagnostic and prognostic value in MS. We conducted a systematic review and meta-analysis of studies that measured peripheral blood and CSF levels of OPN in MS patients and controls to evaluate the diagnostic potential of this biomarker better. We searched PubMed, Web of Science and Scopus databases to find articles that measured OPN concentration in peripheral blood and CSF samples from MS patients up to October 19, 2016...
2018: PloS One
https://www.readbyqxmd.com/read/29346410/an-evaluation-of-multi-probe-locality-sensitive-hashing-for-computing-similarities-over-web-scale-query-logs
#6
Graham Cormode, Anirban Dasgupta, Amit Goyal, Chi Hoon Lee
Many modern applications of AI such as web search, mobile browsing, image processing, and natural language processing rely on finding similar items from a large database of complex objects. Due to the very large scale of data involved (e.g., users' queries from commercial search engines), computing such near or nearest neighbors is a non-trivial task, as the computational cost grows significantly with the number of items. To address this challenge, we adopt Locality Sensitive Hashing (a.k.a, LSH) methods and evaluate four variants in a distributed computing environment (specifically, Hadoop)...
2018: PloS One
https://www.readbyqxmd.com/read/29346378/evaluating-the-impact-of-a-virtual-clinic-on-patient-experience-personal-and-provider-costs-of-care-in-urinary-incontinence-a-randomised-controlled-trial
#7
Georgina Jones, Victoria Brennan, Richard Jacques, Hilary Wood, Simon Dixon, Stephen Radley
OBJECTIVE: To evaluate the impact of using a 'virtual clinic' on patient experience and cost in the care of women with urinary incontinence. MATERIALS AND METHODS: Women, aged > 18 years referred to a urogynaecology unit were randomised to either (1) A Standard Clinic or (2) A Virtual Clinic. Both groups completed a validated, web-based interactive, patient-reported outome measure (ePAQ-Pelvic Floor), in advance of their appointment followed by either a telephone consultation (Virtual Clinic) or face-to-face consultation (Standard Care)...
2018: PloS One
https://www.readbyqxmd.com/read/29346063/linking-data-from-health-surveys-and-electronic-health-records-a-demonstration-project-in-two-chicago-health-center-clinics
#8
Fikirte Wagaw, Catherine A Okoro, Sunkyung Kim, Jessica Park, Fred Rachman
INTRODUCTION: Monitoring and understanding population health requires conducting health-related surveys and surveillance. The objective of our study was to assess whether data from self-administered surveys could be collected electronically from patients in urban, primary-care, safety-net clinics and subsequently linked and compared with the same patients' electronic health records (EHRs). METHODS: Data from self-administered surveys were collected electronically from a convenience sample of 527 patients at 2 Chicago health centers from September through November, 2014...
January 18, 2018: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29345970/the-prevalence-and-significance-of-staphylococcus-aureus-in-patients-with-non-cystic-fibrosis-bronchiectasis
#9
Mark L Metersky, Timothy R Aksamit, Alan Barker, Radmila Choate, Charles L Daley, Leigh A Daniels, Angela DiMango, Edward Eden, David Griffith, Margaret Johnson, Michael Knowles, Anne E O'Donnell, Kenneth Olivier, Matthias Salathe, Byron Thomashow, Gregory Tino, Gerard Turino, Kevin L Winthrop, David Mannino
RATIONALE: Staphylococcus aureus is commonly cultured from the sputum of patients with bronchiectasis, however little is known about the prevalence of the organism in these patients, the characteristics of patients who have grown the organism or its implications. OBJECTIVES: Determine the relationship between S. aureus and pulmonary function, frequency of exacerbations and frequency of hospitalization in patients with bronchiectasis Methods: The Bronchiectasis Research Registry is a database of adults with non-cystic fibrosis bronchiectasis identified from 13 sites within the United States...
January 18, 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29345799/self-criticism-self-report-measures-systematic-review
#10
REVIEW
Alexandra V Rose, Katharine A Rimes
PURPOSE: Self-criticism is a transdiagnostic process that has been attracting research and clinical interest. The accurate measurement of this construct is therefore crucial; however, there are currently numerous measures of self-criticism and no guidelines about which to use in different contexts. This systematic review evaluated the measurement properties of self-report questionnaires of self-criticism. METHODS: OvidSP and Web of Science were used to search through multiple databases, and an initial grey literature search was completed...
January 18, 2018: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/29345588/the-role-of-percutaneous-coronary-intervention-in-the-treatment-of-chronic-total-occlusions-rationale-and-review-of-the-literature
#11
Harsh Agrawal, Richard Lange, Ruben Montanez, Soma Wali, Khan Omar Mohammad, Subrata Kar, Mohamed Teleb, Debabrata Mukherjee
BACKGROUND: Chronic total occlusion (CTO) of a coronary artery is defined as an occluded segment with no antegrade flow and a known or estimated duration of at least 12 weeks. OBJECTIVE: We considered the current literature describing the indications and clinical outcomes for de-novo CTO- percutaneous coronary intervention (PCI), and discuss the role of CTO-PCI and future directions for this procedure. METHOD: Databases (PubMed, the Cochrane Library, Embase, EBSCO, Web of Science, and CINAHL were searched and relevant studies of CTO-PCI were selected for review...
January 16, 2018: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/29345582/is-the-impact-of-starvation-on-the-gut-microbiota-specific-or-unspecific-to-anorexia-nervosa-a-narrative-review-based-on-a-systematic-literature-search
#12
Isabelle Mack, John Penders, Jessica Cook, Jaslyn Dugmore, Nazar Mazurak, Paul Enck
BACKGROUND: The role of the gut microbiota in Anorexia nervosa (AN) has long been neglected by researchers, although the former is known to play an important role in health, disease and weight regulation. Overweight and underweight due to natural states of starvation and refeeding are normal in many vertebrates in their ecological niches. OBJECTIVE: The aim of this review was to compare the similarities and differences between the gut microbiota in eating disorders with conditions of fasting and refeeding in other vertebrates...
January 17, 2018: Current Neuropharmacology
https://www.readbyqxmd.com/read/29345498/effects-of-blueberry-and-cranberry-consumption-on-type-2-diabetes-glycemic-control-a-systematic-review
#13
Dmup Rocha, Aps Caldas, Bp da Silva, Hh Hermsdorff, Rcg Alfenas
The metabolic effects of cranberry and blueberry consumption on glycemic control have been evaluated in vitro and in animal models as well as in human studies, although findings have not been systematically reviewed yet. Therefore, a systematic review was carried out of relevant randomized clinical trials (RCTs) in order to assess the effect of berries (blueberry and cranberry) consumption on type 2 diabetes (T2DM) glycemic control. Some evidences were also discussed on the anti-diabetic mechanisms exerted by berries polyphenols...
January 18, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29345222/development-and-implementation-of-multilocus-sequence-typing-to-study-the-diversity-of-the-yeast-kluyveromyces-marxianus-in-italian-cheeses
#14
Fabrizia Tittarelli, Javier A Varela, Loughlin Gethins, Catherine Stanton, R P Ross, Giovanna Suzzi, Luigi Grazia, Rosanna Tofalo, John P Morrissey
The yeast Kluyveromyces marxianus possesses advantageous traits like rapid growth, GRAS (generally regarded as safe) status and thermotolerance that make it very suitable for diverse biotechnological applications. Although physiological studies demonstrate wide phenotypic variation within the species, there is only limited information available on the genetic diversity of K. marxianus. The aim of this work was to develop a multilocus sequence typing (MLST) method for K. marxianus to improve strain classification and selection...
January 18, 2018: Microbial Genomics
https://www.readbyqxmd.com/read/29345049/cryolipolysis-for-the-treatment-of-submental-fat-review-of-the-literature
#15
REVIEW
Shari R Lipner
BACKGROUND: Submental fat accumulation is a common cosmetic concern. Cryolipolysis utilizes noninvasive cooling to lyse adipocytes. A cryolipolysis device was recently approved for treatment of submental fat. OBJECTIVE: This manuscript provides a review of the preclinical work and clinical trials related to cryolipolysis for the treatment of submental fat. Settings, efficacy, and side effects are also discussed. MATERIALS AND METHODS: A literature search was performed through Pubmed, EMBASE, Web of Science, and CINAHL, using the search terms "cryolipolysis," "submental," and "paradoxical adipose hyperplasia"...
January 17, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29345027/does-flavoured-dentifrice-increase-fluoride-intake-compared-with-regular-toothpaste-in-children-a-systematic-review-and-meta-analysis
#16
REVIEW
Thiago Isidro Vieira, Adrielle Mangabeira, Adílis Kalina Alexandria, Daniele Masterson T P Ferreira, Tatiana Kelly da Silva Fidalgo, Ana Maria Gondim Valença, Lucianne Cople Maia
BACKGROUND: Toothpaste manufacturers encourage through aggressive marketing strategies the overconsumption of fluoridated dentifrices. There are conflicting results regarding fluoride intake from toothpastes in children. AIM: The aim of this systematic review and meta-analysis was to determine whether dentifrice flavour increases fluoride ingestion by children. DESIGN: We included clinical trials on children that evaluated the use of flavoured dentifrice - FD vs regular dentifrice - RD to identify the fluoride intake...
January 18, 2018: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/29344727/work-related-stress-as-a-cardiovascular-risk-factor-in-police-officers-a-systematic-review-of-evidence
#17
N Magnavita, I Capitanelli, S Garbarino, E Pira
PURPOSE: Several studies suggest that work-related stress in police officers may be associated with an increased risk of cardiovascular diseases. A systematic review of studies is, however, still lacking. METHOD: According to PRISMA statement, a systematic search of PubMed, ISI Web of Science, Cinahl and PsychInfo electronic databases was undertaken. Studies published in English between 1/1/2000 and 31/12/2016 were included. A studies quality assessment was performed using the Newcastle Ottawa scale (NOS)...
January 17, 2018: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/29344682/68ga-prostate-specific-membrane-antigen-psma-positron-emission-tomography-pet-for-primary-staging-of-high-risk-prostate-cancer-a-systematic-review
#18
Julia Corfield, Marlon Perera, Damien Bolton, Nathan Lawrentschuk
PURPOSE: To systematically review currently available data on 68Ga-prostate specific membrane antigen (PSMA) positron emission tomography (PET) used for the primary staging of high-risk prostate cancer. METHODS: We performed critical reviews of EMBASE, Web of Science (including MEDLINE) and Cochrane databases in October 2016 according to the Preferred Reporting Items for Systematic Review and Meta-analysis statement. We included studies that utilized 68Ga-PSMA PET for primary staging of prostate cancer...
January 17, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29344622/barriers-to-and-facilitators-of-implementing-enhanced-recovery-pathways-using-an-implementation-framework-a-systematic-review
#19
Alexander B Stone, Christina T Yuan, Michael A Rosen, Michael C Grant, Lauren E Benishek, Elizabeth Hanahan, Lisa H Lubomski, Clifford Ko, Elizabeth C Wick
Importance: Enhanced recovery pathways (ERPs) have the potential to reduce length of hospital stay, costs, and complications following surgery but can be challenging to implement. Objective: To examine the body of literature on ERPs to assess how authors describe barriers and facilitators of ERP implementation and identify, in aggregate, the best practices that should be considered utilizing the Consolidated Framework for Implementation Research (CFIR) to extract these elements and summarize common barriers and facilitators according to its 5 major domains: (1) intervention characteristics, (2) inner setting, (3) outer setting, (4) characteristics of the individuals, and (5) the process of implementation...
January 17, 2018: JAMA Surgery
https://www.readbyqxmd.com/read/29344507/definition-management-and-outcomes-of-acute-kidney-injury-an-international-survey-of-nephrologists
#20
Umar Farooq, Aaron Tober, Vernon Chinchilli, W Brian Reeves, Nasrollah Ghahramani
Background: Acute kidney injury (AKI) is a complex disease burdened by uncertainties of definition, management strategies, and prognosis. This study explores the relationship between demographic characteristics of nephrologists and their perceptions about the definition, management, and follow-up of AKI. Methods: We developed a Web-based survey, the International Survey on Acute Kidney Injury (ISAKI), consisting of 29 items in 4 categories: (1) demographic and practice characteristics, (2) definition of AKI, (3) management of renal replacement therapy (RRT) in AKI, and (4) sequelae of AKI...
December 2017: Kidney Diseases
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