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https://www.readbyqxmd.com/read/28440738/restricted-feeding-modulates-the-daily-variations-of-liver-glutamate-dehydrogenase-activity-expression-and-histological-location
#1
Olivia Vázquez-Martínez, Isabel Méndez, Isaías Turrubiate, Héctor Valente-Godínez, Moisés Pérez-Mendoza, Paola García-Tejada, Mauricio Díaz-Muñoz
Glutamate dehydrogenase is an important enzyme in the hepatic regulation of nitrogen and energy metabolism. It catalyzes one of the most relevant anaplerotic reactions. Although its relevance in liver homeostasis has been widely described, its daily pattern and responsiveness to restricted feeding protocols has not been studied. We explored the daily variations of liver glutamate dehydrogenase transcription, protein, activity, and histochemical and subcellular location in a protocol of daytime food synchronization in rats...
May 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28430046/an-outpatient-methadone-weaning-program-by-a-neonatal-intensive-care-unit-for-neonatal-abstinence-syndrome
#2
Andrew Lai, Patrick Philpot, Jenny Boucher, Andrew Meyer
Through retrospective chart review, this study described characteristics and length of stay for a cohort of newborns discharged on methadone following an inpatient weaning for neonatal abstinence syndrome (NAS). Data were assessed for all term infants born between January 1, 2010, and December 31, 2014, admitted to the hospital with a co-diagnosis of NAS at discharge, for gestational age, length of stay, days on treatment protocol before discharge, time to once-daily interval methadone dosing, and hospital charges, as well as for categorical characteristics...
April 21, 2017: Population Health Management
https://www.readbyqxmd.com/read/28414868/protective-effects-of-diallyl-sulphide-against-ethanol-induced-injury-in-rat-adipose-tissue-and-primary-human-adipocytes
#3
Venkata Harini Kema, Imran Khan, Reshma Jamal, Sandeep Kumar Vishwakarma, Chandrakala Lakki Reddy, Kirti Parwani, Farhin Patel, Dhara Patel, Aleem A Khan, Palash Mandal
BACKGROUND: Alcohol consumption is the fourth leading cause of death and disability worldwide. Several cellular pathways contribute to alcohol mediated tissue injury. Adipose tissue apart from being functioning as an endocrine organ secretes several hormones and cytokines known as adipokines that are known to play a significant role in alcohol induced tissue damage. OBJECTIVE: This study was designed to test the efficacy of diallyl sulphide (DAS) in regulating the alcohol induced outcomes on adipose tissue...
April 17, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28414008/implementation-utilization-and-influence-of-a-community-based-participatory-nutrition-promotion-programme-in-rural-ethiopia-programme-impact-pathway-analysis
#4
Yunhee Kang, Seungman Cha, Sarah Yeo, Parul Christian
OBJECTIVE: A community-based participatory nutrition promotion (CPNP) programme, involving a 2-week group nutrition session, attempted to improve child feeding and hygiene. The implementation, utilization and influence of the CPNP programme were examined by programme impact pathway (PIP) analysis. DESIGN: Five CPNP programme components were evaluated: (i) degree of implementation; (ii) participants' perception of the nutrition sessions; (iii) participants' message recall; (iv) utilization of feeding and hygiene practices at early programme stage; and (v) participants' engagement in other programmes...
April 17, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28411363/animal-models-of-alcoholic-liver-disease-pathogenesis-and-clinical-relevance
#5
Bin Gao, Ming-Jiang Xu, Adeline Bertola, Hua Wang, Zhou Zhou, Suthat Liangpunsakul
Alcoholic liver disease (ALD), a leading cause of chronic liver injury worldwide, comprises a range of disorders including simple steatosis, steatohepatitis, cirrhosis, and hepatocellular carcinoma. Over the last five decades, many animal models that have been useful for the study of ALD pathogenesis have been developed. Recently, a chronic-plus-binge ethanol feeding model was reported. This model induces significant steatosis, hepatic neutrophil infiltration, and liver injury. A clinically relevant model of high-fat diet feeding plus binge ethanol was also developed, which highlights the risk of excessive binge drinking in obese/overweight individuals...
April 14, 2017: Gene Expression
https://www.readbyqxmd.com/read/28409822/non-hazardous-biocatalytic-oxidation-in-nylon-9-monomer-synthesis-on-a-40-gram-scale-with-efficient-downstream-processing
#6
Sofia Milker, Michael J Fink, Florian Rudroff, Marko D Mihovilovic
This paper describes the development of a biocatalytic process on the multi-dozen gram scale for the synthesis of a precursor to Nylon-9, a specialty polyamide. Such materials are growing in demand, but their corresponding monomers are often difficult to synthesize, giving rise to biocatalytic approaches. Here, we implemented cyclopentadecanone monooxygenase as an Escherichia coli whole-cell biocatalyst in a defined medium, together with a substrate feeding-product removal concept, and an optimized downstream processing (DSP)...
April 14, 2017: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/28409756/standardized-slow-enteral-feeding-protocol-reduces-necrotizing-enterocolitis-in-micropremies
#7
S Viswanathan, R Merheb, Xintong Wen, M Collin, S Groh-Wargo
BACKGROUND: Compared to early enteral feeds, delayed introduction and slow enteral feeding advancement to reduce necrotizing enterocolitis (NEC) is not well studied in micropremies (<750g birth weight). METHODS: Pre-post case control study. Micropremies who followed a standardized slow enteral feeding (SSEF) protocol (September 2009 to March 2015) were compared with a similar group of historical controls (PreSSEF, January 2003 to July 2009). Enteral feeding withheld for first 10-14 days and advanced at <10 ml/kg/day in the SSEF group...
April 8, 2017: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/28397621/performance-of-holstein-calves-receiving-equal-quantities-of-milk-at-fixed-or-variable-amounts-per-day-during-milk-feeding-period
#8
M Khani, F Ahmadi, M Ariana, S Omidian, S Sharifi, M H Ghaffari, H Beiranvand
Two experiments were conducted to determine the effects of feeding equal quantities of milk during the pre-weaning period through different milk-feeding regimes on calf growth, starter intake and selected blood metabolites. In experiment 1, 44 female Holstein calves (3 days of age and 39.2±4.3 kg of BW) were distributed randomly to one of two milk-feeding programs (1 calf per pen; 22 pens per treatment group): (1) consistent (CONS; 6 l/day of milk from days 3 to 60 and 3 l/day from days 61 to 65 of age) or (2) step-up/step-down (SUSD; 5 l/day of milk from days 3 to 15, 8 l/day from days 16 to 40, 6 l/day from days 41 to 50, 3 l/day from days 51 to 60 and then 2 l/day from days 61 to 65 of age)...
April 11, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28393691/biotechnological-approaches-for-production-of-anti-cancerous-compounds-resveratrol-podophyllotoxin-and-zerumbone
#9
Krishnadas Nandagopal, Mihir Halder, Biswabhusan Dash, Sanghamitra Nayak, Sumita Jha
Secondary metabolites from numerous plant sources have been developed as anti-cancer reagents and compounds such as resveratrol, podophyllotoxin and zerumbone are of particular importance in this regard. Since their de novo chemical synthesis is both arduous and commercially expensive, there has been an impetus to develop viable, biotechnological methods of production. Accordingly, this review focuses on recent developments in the field, highlighting the use of micropropagation, cell suspension cultures, callus cultures, hairy root cultures, recombinant microbes and genetically modified higher plants...
April 4, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28391763/detection-by-real-time-pcr-and-pyrosequencing-of-the-cry1ab-and-cry1ac-genes-introduced-in-gm-constructs
#10
Frederic Debode, Erik Janssen, Claude Bragard, Gilbert Berben
The presence of GMOs in food and feed is mainly detected by the use of targets focusing on promoters and terminators. As some genes are frequently used in GM construction, they also constitute excellent screening elements and their use is increasing. In this work, we propose a new target for the detection of cry1Ab and cry1Ac genes by real-time PCR and pyrosequencing. The specificity, sensitivity and robustness of the real-time PCR method were tested following the recommendations of international guidelines and the method met the expected performance criteria...
April 10, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/28390757/multistage-sclerotherapy-for-extensive-lymphatic-malformations-with-airway-involvement-in-infants-a-protocol-to-prevent-tracheotomy
#11
An-Wei Chen, Tao Wang, Ying-Ying Huang, Shao-Hua Liu
PURPOSE: The management of extensive head and neck lymphatic malformations (LMs) in infants is challenging because of life-threatening upper airway compression. The aim of this study was to present a management protocol and evaluate the clinical outcomes for preventing tracheotomy in these patients. MATERIALS AND METHODS: Fifteen infants with extensive head and neck LMs and airway involvement were enrolled from August 2010 through September 2015 at the Qilu Hospital of Shandong University (Jinan, China)...
March 18, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28388951/implementing-the-emergency-triage-assessment-and-treatment-plus-admission-care-etat-clinical-practice-guidelines-to-improve-quality-of-hospital-care-in-rwandan-district-hospitals-healthcare-workers-perspectives-on-relevance-and-challenges
#12
Celestin Hategeka, Leah Mwai, Lisine Tuyisenge
BACKGROUND: An emergency triage, assessment and treatment plus admission care (ETAT+) intervention was implemented in Rwandan district hospitals to improve hospital care for severely ill infants and children. Many interventions are rarely implemented with perfect fidelity under real-world conditions. Thus, evaluations of the real-world experiences of implementing ETAT+ are important in terms of identifying potential barriers to successful implementation. This study explored the perspectives of Rwandan healthcare workers (HCWs) on the relevance of ETAT+ and documented potential barriers to its successful implementation...
April 7, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28386520/behavioral-and-stereological-analysis-of-the-effects-of-intermittent-feeding-diet-on-the-orally-administrated-mdma-ecstasy-in-mice
#13
Zeinab Ebrahimian, Zeinab Karimi, Mohammad Javad Khoshnoud, Mohammad Reza Namavar, Bahram Daraei, Mohsen Raza Haidari
Background: 3,4-methylenedioxy-methamphetamine or MDMA (also known as "ecstasy" or "molly") is a commonly abused drug that affects behavior and can lead to neuronal damage. Intermittent feeding is an effective dietary protocol that promotes neuroprotection and improves behavioral outcomes in animal models of neurotoxicity and neurodegenerative diseases. In this study, we investigated the behavioral and histological outcomes of the effect of intermittent feeding on the orally administered MDMA in mice. Methods: The animals (male albino mice) were divided into four groups: ad libitum (AL), intermittent feeding (IF) (food given every other day), and AL and IF control groups...
January 2017: Innovations in Clinical Neuroscience
https://www.readbyqxmd.com/read/28382771/patterns-of-cultural-consensus-and-intracultural-diversity-in-ghanaian-complementary-feeding-practices
#14
Nikhila Kalra, Gretel Pelto, Charlotte Tawiah, Stephanie Zobrist, Peiman Milani, Grace Manu, Amos Laar, Megan Parker
Designing effective interventions to improve infant and young child (IYC) feeding requires knowledge about determinants of current practices, including cultural factors. Current approaches to obtaining and using research on culture tend to assume cultural homogeneity within a population. The purpose of this study was to examine the extent of cultural consensus (homogeneity) in communities where interventions to improve IYC feeding practices are needed to address undernutrition during the period of complementary feeding...
April 6, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28382696/aiding-targeted-protein-degradation-in-drosophila
#15
Xu Zhang, Frank Schnorrer
Conditional protein depletion is highly desirable for investigating protein functions in complex organisms. In this issue, Bence and colleagues combined auxin-inducible degradation with CRISPR, establishing an elegant tool to control protein levels. They achieve precise spatio-temporal control of protein degradation during Drosophila oogenesis and early embryogenesis by combining suitable GAL4 drivers (spatial control) with auxin feeding protocols (temporal control).
April 2017: FEBS Journal
https://www.readbyqxmd.com/read/28380012/finishing-pigs-that-are-divergent-in-feed-efficiency-show-small-differences-in-intestinal-functionality-and-structure
#16
Barbara U Metzler-Zebeli, Peadar G Lawlor, Elizabeth Magowan, Ursula M McCormack, Tânia Curião, Manfred Hollmann, Reinhard Ertl, Jörg R Aschenbach, Qendrim Zebeli
Controversial information is available regarding the feed efficiency-related variation in intestinal size, structure and functionality in pigs. The present objective was therefore to investigate the differences in visceral organ size, intestinal morphology, mucosal enzyme activity, intestinal integrity and related gene expression in low and high RFI pigs which were reared at three different geographical locations (Austria, AT; Northern Ireland, NI; Republic of Ireland, ROI) using similar protocols. Pigs (n = 369) were ranked for their RFI between days 42 and 91 postweaning and low and high RFI pigs (n = 16 from AT, n = 24 from NI, and n = 60 from ROI) were selected...
2017: PloS One
https://www.readbyqxmd.com/read/28379192/attack-classification-schema-for-smart-city-wsns
#17
Victor Garcia-Font, Carles Garrigues, Helena Rifà-Pous
Urban areas around the world are populating their streets with wireless sensor networks (WSNs) in order to feed incipient smart city IT systems with metropolitan data. In the future smart cities, WSN technology will have a massive presence in the streets, and the operation of municipal services will be based to a great extent on data gathered with this technology. However, from an information security point of view, WSNs can have failures and can be the target of many different types of attacks. Therefore, this raises concerns about the reliability of this technology in a smart city context...
April 5, 2017: Sensors
https://www.readbyqxmd.com/read/28377725/gut-microbiota-dependent-metabolite-trimethylamine-n-oxide-contributes-to-cardiac-dysfunction-in-western-diet-induced-obese-mice
#18
Kui Chen, Xiaoqian Zheng, Mingchen Feng, Dongliang Li, Hongqi Zhang
Excessive consumption of diets high in sugars and saturated fat, frequently known as western diet (WD), may lead to obesity and metabolic syndrome. Recent evidence shows that WD-induced obesity impairs cardiac function, but the underlying mechanisms are not fully understood. Trimethylamine N-oxide (TMAO), a gut microbiota-dependent metabolite of specific dietary nutrients, has emerged as a key contributor to cardiovascular disease pathogenesis. We tested the hypothesis that elevated circulating TMAO levels contribute to cardiac dysfunction in WD-induced obesity...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28376725/improving-feeding-and-growth-of-hiv-positive-children-through-nutrition-training-of-frontline-health-workers-in-tanga-tanzania
#19
Bruno F Sunguya, Linda B Mlunde, David P Urassa, Krishna C Poudel, Omary S Ubuguyu, Namala P Mkopi, Germana H Leyna, Anna T Kessy, Keiko Nanishi, Akira Shibanuma, Junko Yasuoka, Masamine Jimba
BACKGROUND: Nutrition training can boost competence of health workers to improve children's feeding practices. In this way, child undernutrition can be ameliorated in general populations. However, evidence is lacking on efficacy of such interventions among Human Immunodeficiency Virus (HIV)-positive children. We aimed to examine the efficacy of a nutrition training intervention to improve midlevel providers' (MLPs) nutrition knowledge and feeding practices and the nutrition statuses of HIV-positive children in Tanga, Tanzania...
April 4, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28376549/incidence-of-nasogastric-and-gastrostomy-tube-at-discharge-is-reduced-after-implementing-an-oral-feeding-protocol-in-premature-%C3%A2-30-weeks-infants
#20
Michael D Kamitsuka, Patricia A Nervik, Shana L Nielsen, Reese H Clark
Objective Reduce the number of infants requiring home tube feeds by initiating an oral feeding protocol (OFP). Study Design All infants < 30 weeks' gestation were eligible. The OFP involved four steps: encourage non-nutritive suck before 30 weeks, oral motor exercises starting as early as 30 weeks, swallowing exercises as early as 31 weeks, and an infant-driven oral feeding pathway as early as 32 weeks. Results The study included 129 infants before the protocol (January 2010 to December 2011) and 141 infants after the protocol (March 2013 to May 2015)...
May 2017: American Journal of Perinatology
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