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https://www.readbyqxmd.com/read/29149584/the-ill-fated-quest-for-fame-in-psychological-research
#1
Alexandra M Freund
The question "Am I famous yet?" directs our attention to the outcome of the journey of being a psychological scientist. There is nothing inherently wrong with wanting to achieve the highest possible outcomes when pursuing a goal. However, for a researcher, fame is an outcome that is very vague, abstract, distal, and unlikely to be attained. Focusing on this outcome might undermine motivation and persistence in the difficult endeavor of doing excellent research and contributing to psychological knowledge. To become an excellent psychological scientist might be a better outcome to which to aspire...
November 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/29149247/quantitative-proteomic-profiling-of-bovine-follicular-fluid-during-follicle-development
#2
Rodrigo de Andrade Ferrazza, Elizabeth Moreira Dos Santos Schmidt, Monika Mihm Carmichael, Fabiana Ferreira de Souza, Richard Burchmore, Roberto Sartori, Peter David Eckersall, João Carlos Pinheiro Ferreira
Bovine follicular fluid (FF) constitutes the microenvironment of follicles and includes various biologically active proteins. We performed a study involving 18 healthy non-lactating Holstein cows to determine the protein expression profile of FF at key-stages of follicular development. Follicles were individually aspirated in vivo at pre-deviation (F1∼7.0mm); deviation (F1∼8.5mm); post-deviation (F1∼12.0mm); and pre-ovulatory stages of follicle development, which were confirmed by measurement of follicular estradiol and progesterone concentrations...
November 15, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29149022/pyogenic-brain-abscess-caused-by-peptostreptococcus-in-a-patient-with-hiv-1-infection
#3
Jose Armando Gonzales Zamora, Luis Alberto Espinoza
In the setting of HIV, cerebral lesions are usually secondary to lymphoma and opportunistic infections; however, in patients with CD4 counts above 200 cells/uL, other pathologies such as pyogenic brain abscess could gain importance. The microbiology of pyogenic brain abscess has Staphylococcus and Streptococcus as the leading etiologic pathogens in immunocompetent individuals. Peptostreptococcus is also recognized as a common cause of brain abscess in this patient population. In HIV-infected individuals, there have been sporadic reports of Peptostreptococcus infections but none of brain abscess...
November 17, 2017: Diseases (Basel)
https://www.readbyqxmd.com/read/29149019/incidence-and-consequences-of-near-drowning-related-pneumonia-a-descriptive-series-from-martinique-french-west-indies
#4
Laura Cerland, Bruno Mégarbane, Hatem Kallel, Yanick Brouste, Hossein Mehdaoui, Dabor Resiere
Drowning represents one major cause of accidental death. Near-drowning patients are exposed to aspiration that may result in pneumonia with life-threatening consequences. We designed this descriptive study to investigate the frequency, nature, and consequences of post-drowning pneumonia. One hundred and forty-four near-drowning patients (33 children and 111 adults) admitted during four years to the University Hospital of Martinique, French Indies, were included. Patients presented pre-hospital cardiac arrest (41%) and exhibited acute respiratory failure (54%), cardiovascular failure (27%), and lactic acidosis (75%) on admission...
November 17, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29148420/the-expression-of-mrna-for-peptidylarginine-deiminase-type-2-and-type-4-in-bone-marrow-cd34-cells-in-rheumatoid-arthritis
#5
Tatsuo Nagai, Yu Matsueda, Tetsuya Tomita, Hideki Yoshikawa, Shunsei Hirohata
OBJECTIVES: Antibodies directed to citrullinated proteins are highly specific for rheumatoid arthritis (RA). Citrullination is catalyzed by peptidylarginine deiminase (PAD) enzymes. The current study examined the mRNA expression of PADI2 and PADI4 in bone marrow (BM) CD34+ cells from RA patients. METHODS: CD34+ cells were purified from BM samples obtained from 48 RA patients and from 30 osteoarthritis (OA) patients during joint operations via aspiration from the iliac crest...
November 14, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29148123/donohue-syndrome-a-review-of-literature-case-series-and-anesthetic-considerations
#6
REVIEW
Alana Kirkwood, Grant Stuart, Louise Harding
BACKGROUND: Donohue syndrome is a rare autosomal recessive disorder of insulin resistance, causing a functional defect in insulin receptor function, and affecting the ability of the insulin to bind the receptor. Features include severe hyperinsulinism and fasting hypoglycemia, along with severe failure to thrive despite feeding. An accelerated fasting state results in muscle wasting, decreased subcutaneous fat, and an excess of thick skin. A reduced thoracic diameter is accentuated by increased abdominal distension, which impacts on respiratory reserve...
November 17, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29147919/alterations-to-swallowing-physiology-as-the-result-of-effortful-swallowing-in-healthy-seniors
#7
Sonja M Molfenter, Chuan-Ya Hsu, Ying Lu, Cathy L Lazarus
A significant proportion of healthy seniors report difficulty swallowing, thought to result from age-related decline in muscle bulk/function. Effortful Swallowing (ES) is used both as a compensatory maneuver to improve pharyngeal propulsion/clearance and has been proposed as an exercise to improve pharyngeal strength. This study sought to quantify the immediate kinematic, temporal, and functional changes during an ES maneuver to quantify its exercise potential to combat age-related changes in swallowing. Videofluoroscopy data were collected from 44 healthy seniors (21 male) over 65 years old (mean = 76...
November 17, 2017: Dysphagia
https://www.readbyqxmd.com/read/29147753/defective-wnt-signaling-associates-with-bone-marrow-fibrosis-a-cross-sectional-cohort-study-in-a-family-with-wnt1-osteoporosis
#8
R E Mäkitie, R Niinimäki, S Kakko, T Honkanen, P E Kovanen, O Mäkitie
This study explores bone marrow function in patients with defective WNT1 signaling. Bone marrow samples showed increased reticulin and altered granulopoiesis while overall hematopoiesis was normal. Findings did not associate with severity of osteoporosis. These observations provide new insight into the role of WNT signaling in bone marrow homeostasis. INTRODUCTION: WNT signaling regulates bone homeostasis and survival and self-renewal of hematopoietic stem cells. Aberrant activation may lead to osteoporosis and bone marrow pathology...
November 16, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29147594/lactobacillus-gasseri-causing-bilateral-empyema
#9
Angela Esquibel, Ala S Dababneh, Bharath Raj Palraj
Lactobacilli are common commensal bacteria found in the gastrointestinal and genitourinary tract. Although they are usually thought to be nonpathogenic, there have been several cases that demonstrate severe infections caused by these microorganisms. This is a case of a 49-year-old male with previously undiagnosed type two diabetes mellitus who presented with a 3-month history of cough and was found to have right sided Lactobacillus gasseri empyema for which he underwent video-assisted thoracoscopic surgery (VATS) with chest tube placement...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29147454/late-onset-chemo-radiation-induced-tracheoesophageal-fistula-in-squamous-cell-cancer-of-the-lung
#10
Ashraf Abugroun, Fatima Ahmed, Namrata Singh, Mojtaba Nadiri
We report a 72-year-old male with past medical history of stage IV squamous lung cancer treated with radiation therapy and chemotherapy with gemcitabine/carboplatin. One year later, he presented with hemoptysis treated with another session of palliative radiotherapy. Two weeks later, patient developed aspiration pneumonia and further workup showed trachea-esophageal fistula documented by barium swallow. This case shows a rare complication of chemotherapy and radiation therapy on the setting of primary lung cancer...
October 2017: World Journal of Oncology
https://www.readbyqxmd.com/read/29146632/the-evolution-of-a-one-stop-outpatient-manual-vacuum-aspiration-service-for-termination-of-pregnancy
#11
Joanna Speedie, Stephen Robson
No abstract text is available yet for this article.
November 16, 2017: Journal of Family Planning and Reproductive Health Care
https://www.readbyqxmd.com/read/29146229/evaluating-the-projected-surgical-impact-of-reclassifying-noninvasive-encapsulated-follicular-variant-of-papillary-thyroid-cancer-as-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features
#12
Rajshri Mainthia, Heather Wachtel, Yufei Chen, Elizabeth Mort, Sareh Parangi, Peter M Sadow, Carrie C Lubitz
BACKGROUND: The reclassification of noninvasive encapsulated follicular variant of papillary thyroid cancer to noninvasive follicular thyroid neoplasm with papillary-like nuclear features will reduce nonefficacious and potentially harmful care. Reclassification is estimated in 18.6% of patients with papillary thyroid carcinoma; we aimed to quantify the implications of this change. METHODS: Pathology reports from April 2006 to April 2016 were reviewed to isolate cases that would have been designated as neoplasm with papillary-like nuclear features...
November 13, 2017: Surgery
https://www.readbyqxmd.com/read/29146168/bone-marrow-derived-mesenchymal-stromal-cells-enhanced-by-platelet-rich-plasma-maintain-adhesion-to-scaffolds-in-arthroscopic-simulation
#13
Alexander R Hoberman, Carl Cirino, Mary Beth McCarthy, Mark P Cote, Leo Pauzenberger, Knut Beitzel, Augustus D Mazzocca, Felix Dyrna
PURPOSE: To assess the response of bone marrow-derived mesenchymal stromal cells (bMSCs) enhanced by platelet-rich plasma (PRP) in the setting of a normal human tendon (NHT), a demineralized bone matrix (DBM), and a fibrin scaffold (FS) with simulated arthroscopic mechanical washout stress. METHODS: Bone marrow was aspirated from the humeral head and concentrated. BMSCs were counted, plated, and grown to confluence. Cells were seeded onto 3 different scaffolds: (1) NHT, (2) DBM, and (3) FS...
November 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29145979/current-ultrasound-application-in-the-foot-and-ankle
#14
REVIEW
Nahum Michael Beard, Robert Patrick Gousse
This article is a comprehensive review of the current utilizations of ultrasound in the treatment of orthopedic conditions of the foot and ankle. It reviews the diagnostic and interventional applications to commonly encountered lower-extremity ailments, including plantar fasciosis, tendinosis, and peripheral nerve disorders. It also outlines minimally invasive ultrasound-guided procedures and emerging therapies as alternatives to current treatments. These emerging therapies can be used to assist surgeons and provide options for patients needing intervention...
January 2018: Orthopedic Clinics of North America
https://www.readbyqxmd.com/read/29145967/bone-intramedullary-reaming-grafts-the-fracture-site-with-cd146-skeletal-progenitors-and-downmodulates-the-inflammatory-environment
#15
Leonardo R Rocha, Rafaela C Sartore, Ana C Leal, Rhayra B Dias, Maria Eugenia L Duarte, João Antônio M Guimarães, Danielle C Bonfim
INTRODUCTION: Femoral shaft fractures generally occur in young adults following a high-energy trauma and are prone to delayed union/non-union. Novel therapies to stimulate bone regeneration will have to mimic some of the aspects of the biology of fracture healing; however, which are these aspects is unclear. Locked intramedullary nailing is the current treatment of choice for the stabilisation of femur shaft fractures, and it is associated with accelerated healing and increased union rates...
October 2017: Injury
https://www.readbyqxmd.com/read/29145904/-an-older-man-with-a-supraclavicular-mass
#16
A M Heerink, P Noë, P H P Groeneveld
An 80-year-old man, originally from Vietnam, was examined for a painful supraclavicular mass on the right side. Puncture and aspiration of the mass revealed purulent fluid. Examination of the aspirate showed acid-fast bacteria, consistent with tuberculous lymphadenitis. The patient was successfully treated with a 4-drug regimen.
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29145466/serum-tsh-levels-as-a-predictor-of-malignancy-in-thyroid-nodules-a-prospective-study
#17
Lenara Golbert, Ana Patrícia de Cristo, Carlo Sasso Faccin, Mauricio Farenzena, Heloísa Folgierini, Marcia Silveira Graudenz, Ana Luiza Maia
BACKGROUND: The role of serum TSH concentrations as a predictor of malignancy of thyroid nodule remains unclear. OBJECTIVE: To prospectively evaluate the usefulness of serum TSH levels as a predictor of malignancy in thyroid nodules. METHODS: Patients with thyroid nodule(s) who underwent fine-needle aspiration biopsy under ultrasonographic guidance in a tertiary, university-based hospital were consecutively evaluated. Patients with known thyroid cancer and/or patients receiving thyroid medication were excluded...
2017: PloS One
https://www.readbyqxmd.com/read/29145304/partially-cystic-thyroid-nodules-in-ultrasound-guided-fine-needle-aspiration-prevalence-of-thyroid-carcinoma-and-ultrasound-features
#18
Wenbo Li, Qingli Zhu, Yuxin Jiang, Qing Zhang, Zhilan Meng, Jian Sun, Jianchu Li, Qing Dai
Partially cystic thyroid nodules (PCTNs) are common on ultrasound (US). However, there are insufficient data on the prevalence of thyroid carcinoma among such nodules. The purpose of this study was thus to evaluate the prevalence and differentiation of partially cystic thyroid cancers in US-guided fine needle aspiration (FNA).A total of 1342 consecutive patients with 1360 thyroid nodules underwent prospective US diagnosis and FNA biopsy. In total, 281 nodules (20.7%) were partially cystic lesions. The nodules were prospectively analyzed based on US features (ie, solid portion positions, shapes, margins, and microcalcifications) and US diagnosis (benign, suspicious, or malignant)...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29144794/endoscopic-ultrasound-guided-fine-needle-aspiration-eus-fna-in-the-diagnosis-of-adrenal-metastasis-in-a-high-risk-population
#19
Catherine D Zhang, Dana Erickson, Michael J Levy, Ferga C Gleeson, Diva R Salomao, Danae A Delivanis, Irina Bancos
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in the diagnosis of adrenal metastasis in a high-risk population Objective: While the left adrenal gland is readily accessible via endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), data regarding the utility of EUS-FNA in the diagnosis of adrenal lesions remain limited. We aimed to 1) describe the clinical context, adverse event rate, and diagnostic performance of EUS-FNA and 2) compare the safety profile and diagnostic accuracy of EUS-FNA with percutaneous adrenal biopsy...
November 16, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29144056/oropharyngeal-dysphagia-profiles-in-individuals-with-oculopharyngeal-muscular-dystrophy
#20
L C Tabor, E K Plowman, C Romero-Clark, S Youssof
BACKGROUND: Although dysphagia represents a hallmark manifestation of oculopharyngeal muscular dystrophy (OPMD), limited knowledge exists regarding the underlying nature of oropharyngeal swallowing impairments in this patient population. We aimed to delineate global pharyngeal dysphagia profiles in OPMD and identify the prevalence and physiologic associations of impairments in swallowing safety and efficiency. METHODS: Twenty-two individuals with OPMD completed a videofluoroscopic swallowing evaluation...
November 16, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
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