keyword
https://read.qxmd.com/read/38046974/ga68-fapi-imaging-and-lu177-fapi-therapy-in-a-case-of-metastatic-solitary-fibrous-tumor
#21
Karuna Luthra, Vikram Lele, Kallur Kumar
Solitary fibrous tumor (SFT) of the central nervous system (previously called hemangiopericytoma) is a rare mesenchymal tumor. Malignant SFT has a tendency to recur after surgery and can metastasize to distant organs. Treatment options for metastatic disease are limited. This case demonstrated high expression of FAP (fibroblast activating protein) in all metastatic sites with Ga-FAPI positron emission tomography-computed tomography imaging. Subsequently, the patient was treated with Lu177-FAPI-targeted radionuclide therapy...
2023: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://read.qxmd.com/read/37974783/unveiling-a-rarity-a-case-report-on-glomangiopericytoma-in-the-nasal-cavity
#22
JOURNAL ARTICLE
Akshat Kushwaha, Ngohlaki Khaimeichho, Sreerekha Jinkala, Lokesh Kumar Penubarthi
UNLABELLED: Sino-nasal glomangiopericytoma is a rare benign tumour comprising only about 0.5% of all sino-nasal tumours. Presenting as a bleeding nasal mass, it is among the myriad of differential diagnoses for the same. Clinical characterisation of mass becomes difficult; hence, histopathology and immunohistocytochemistry play an essential role in clenching the diagnosis. Optimal treatment includes complete tumour excision with endoscopic or open approaches with or without preoperative embolization and a long post-operative follow-up period...
December 2023: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/37955760/postoperative-stereotactic-radiosurgery-for-intracranial-solitary-fibrous-tumors-systematic-review-and-pooled-quantitative-analysis
#23
REVIEW
Danielle Golub, Joshua D McBriar, Hayley Donaldson, Taylor Wong, Prashin Unadkat, Timothy G White, Eric T Quach, Sara Haddock, Bhargava Chitti, Yonah Ziemba, Anuj Goenka, Samuel Singer, Michael Schulder, Amir R Dehdashti
BACKGROUND: Intracranial solitary fibrous tumors (SFTs), formerly hemangiopericytomas (HPCs), are rare, aggressive dural-based mesenchymal tumors. While adjuvant radiation therapy has been suggested to improve local tumor control (LTC), especially after subtotal resection, the role of postoperative stereotactic radiosurgery (SRS) and the optimal SRS dosing strategy remain poorly defined. METHODS: PubMed, EMBASE, and Web of Science were systematically searched according to PRISMA guidelines for studies describing postoperative SRS for intracranial SFTs...
November 13, 2023: Journal of Neuro-oncology
https://read.qxmd.com/read/37909001/three-cases-of-non-islet-cell-tumor-hypoglycemia-highlighting-efficacy-of-glucocorticoid-treatment
#24
Kimberly Voon, Aaron Simpson, Peter Gerard Fegan, John P Walsh
Non-islet cell tumor hypoglycemia (NICTH) is a rarely encountered cause of hypoglycemia. It is most often caused by tumor secretion of precursor insulin-like growth factor-2 (IGF-2) which, in high concentrations, binds to insulin receptors exerting insulin-like metabolic effects. It is often associated with mesenchymal and hepatic tumors. We describe 3 cases of NICTH: a 60-year-old man with an unresectable pelvic sarcoma and two women ages 43 and 57 with metastatic hemangiopericytoma. Biochemical assessment identified hypoglycemia associated with suppressed insulin, c-peptide, and beta-hydroxybutyrate levels...
July 2023: JCEM Case Rep
https://read.qxmd.com/read/37908275/hypoglycemia-from-metastatic-meningeal-solitary-fibrous-tumor-occurring-over-two-decades-after-initial-diagnosis
#25
John J Orrego, Joseph A Chorny
Despite multiple intracranial and extracranial relapses associated with a widely metastatic meningeal solitary fibrous tumor (formerly classified as hemangiopericytoma), a 66-year-old type 2 diabetic man was first diagnosed with paraneoplastic hypoglycemia 23 years after the original diagnosis and 12 years after the onset of extracranial metastatic disease. An enlarging mass entirely replacing the left kidney measuring 11.6 × 10 × 28 cm, which had not been locally treated before, was considered to be the putative source of IGF-2 excess...
January 2023: JCEM Case Rep
https://read.qxmd.com/read/37899318/-perivascular-epithelioid-cell-tumor-of-the-lung-a-clinicopathological-analysis-of-eight-cases
#26
JOURNAL ARTICLE
J Li, R P Huang, P Pang, X Guo, Y H Wang, L C Guo, S Huang
Objective: To investigate the clinicopathological features of perivascular epithelioid cell tumor (PEComa) of the lung. Methods: Eight PEComa cases of the lung diagnosed at the First Affiliated Hospital of Soochow University, Suzhou, China from July 2008 to December 2021 were collected and subject to immunohistochemical staining, fluorescence in situ hybridization and next generation sequencing. The relevant literature was reviewed and the clinicopathological features were analyzed. Results: There were 5 males and 3 females, aged from 18 to 70 years (mean 39 years)...
November 8, 2023: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://read.qxmd.com/read/37801720/intracranial-solitary-fibrous-tumor-mimicking-meningioma
#27
JOURNAL ARTICLE
Xiaowei Tao, Xuelei Yan, Yifei Zhang, Shiqiang Qin
Solitary fibrous tumor (SFT) is a clinically rare tumor derived from mesenchymal spindle cells. Central nervous system SFT represents only 0.09% of tumors occurring on the meninges, while intracranial solitary fibrous tumors (ISFT) are even more rare. Due to the similar genetic characteristics it shares with hemangiopericytoma, in 2016, the World Health Organization (WHO) classified it as a single disease called solitary fibrous tumor (SFT)/hemangiopericytoma. We reported a case of a 60-year-old female with an intracranial solitary fibrous tumor (ISFT)...
October 1, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/37792156/glomangiosarcoma-like-anaplastic-transformation-in-papillary-thyroid-carcinoma-a-novel-form-of-heterologous-differentiation-and-a-systematic-review-of-heterologous-element-prevalence
#28
JOURNAL ARTICLE
Rayan Rammal, Jason K Wasserman, Aatur D Singhi, Christopher C Griffith, Raja R Seethala
Anaplastic thyroid carcinoma (ATC) demonstrates a wide variety of morphologies and is characteristically associated with a differentiated thyroid carcinoma component. Heterologous differentiation is a rare, potentially challenging phenomenon in ATC, mostly observed as osteosarcomatous or chondrosarcomatous differentiation. We now describe a novel 'glomangiosarcoma-like' differentiation, review our archival experience from two institutions (UPMC, CC), and perform a systematic review for the prevalence of heterologous elements in ATC...
December 2023: Endocrine Pathology
https://read.qxmd.com/read/37779748/recurrent-solitary-fibrous-tumor-in-a-73-year-old-male-presenting-with-small-bowel-obstruction-a-case-report
#29
Adam Talaat, Aron Mcguirt
Solitary fibrous tumors (SFTs) are rare soft tissue tumors that can arise in the abdomen, pleura, and central nervous system, among other sites. Surgical resection is the mainstay of management, although recurrence rates remain substantial. This case describes a 73-year-old male treated surgically for both a recurrent SFT and small bowel obstruction (SBO) secondary to adhesions. The patient had undergone numerous intra-abdominal operations for malignant SFT since 1994, highlighting the importance of meticulous resection at the initial presentation of local disease...
August 2023: Curēus
https://read.qxmd.com/read/37743335/-mesenchymal-and-non-meningothelial-tumors-involving-the-central-nervous-system
#30
JOURNAL ARTICLE
Soichi Oya, Chiaki Murakami
In the World Health Organization Classification of Brain Tumors Fifth Edition, mesenchymal non-meningothelial tumors involving the central nervous system are divided into three major categories: soft tissue tumors, chondro-osseous tumors, and notochordal tumors. Soft tissue tumors are classified into four groups: fibroblastic and myofibroblastic tumors, vascular tumors, skeletal muscle tumors, and tumors of uncertain differentiation. This article will focus on solitary fibrous tumors(SFTs), which are frequently encountered clinically and continue to undergo classification revisions in the 5th edition, and outline the three newly added histological diagnoses...
September 2023: No Shinkei Geka. Neurological Surgery
https://read.qxmd.com/read/37743328/-classification-and-molecular-diagnosis-of-benign-brain-tumors
#31
JOURNAL ARTICLE
Koji Yoshimoto
Classification and molecular diagnosis of benign brain tumors, focusing on cranial and pasaspinal nerve tumors, meningioma, mesenchymal, and non-meningothelial tumors involving the central nervous system(CNS)has been reviewed based on the 5th edition of the World Health Organization Classification of Tumors of the Central Nervous System. In sporadic schwannomas, the novel fusion gene SH3PXD2A-HTRA1 , which activates the MAPK pathway, has been discovered. Meningioma shows frequent chromosomal alterations, including at the NF2 locus...
September 2023: No Shinkei Geka. Neurological Surgery
https://read.qxmd.com/read/37711282/complete-resection-of-a-torcular-herophili-hemangiopericytoma-without-sinus-reconstruction-a-case-report-and-review-of-the-literature
#32
Salah-Edine Safi, Julie Godfrain, Herbert Rooijakkers, Frederic Collignon
A 78-year-old woman presented to the emergency department with mild headaches and a sudden onset of blurred vision. Computerized tomography scan and magnetic resonance imaging showed what was described at first as a meningioma invading and occluding the torcular Herophili, the posterior third of the superior sagittal sinus and the proximal part of the right transverse sinus. Gross total resection of the tumor was performed without reconstructing dural sinuses. The patient was discharged home without new neurological deficit...
2023: Case Reports in Surgery
https://read.qxmd.com/read/37636140/separation-surgery-and-adjuvant-carbon-ion-radiotherapy-for-a-recurrent-solitary-fibrous-tumor-hemangiopericytoma-a-case-report
#33
JOURNAL ARTICLE
Yusuke Tomomatsu, Eiji Takasawa, Shintaro Shiba, Masahiko Okamoto, Hayato Ikota, Kazuhiro Inomata, Akira Honda, Sho Ishiwata, Tokue Mieda, Yoichi Iizuka, Tatsuya Ohno, Hirotaka Chikuda
No abstract text is available yet for this article.
July 27, 2023: Spine surgery and related research
https://read.qxmd.com/read/37632344/head-and-neck-hemangiopericytoma-a-rare-case-report-and-literature-review
#34
JOURNAL ARTICLE
Hanlin Liu, Yuting Lu, Qing He, Xiaolin Cao
Hemangiopericytomas (HPCs) are rare vascular tumors, and head and neck hemangiopericytoma (HNHPC) accounts for 11% to 16% of all HPCs, possibly occurring at any age. However, according to a recent study, HNHPC was most frequently observed in middle-aged adults and had a slight predominance of female patients. In the present case, we report the successful treatment of HNHPC.
August 26, 2023: Ear, Nose, & Throat Journal
https://read.qxmd.com/read/37608822/diagnosis-and-management-of-a-pelvic-solitary-fibrous-tumor-in-a-postmenopausal-woman-a-case-report
#35
Constant Ndjapa-Ndamkou, Sharol Ngwenya, Dimitrije Mamontov, Langanani Mbodi, Logie Govender, Thifhelimbilu Luvhengo, Lawrence Chauke
BACKGROUND: Solitary fibrous tumors, previously known as hemangiopericytomas, originate from mesenchymal tissue and can occur at many body sites, such as the thorax, head and neck, retroperitoneal space and abdomen. These tumors are generally rare and pelvic location is extremely uncommon. Consequently, pelvic solitary tumors could be mistaken for ovarian cancer in menopausal women. This report presents a case of pelvic solitary tumor to highlight the importance of considering this diagnosis in a postmenopausal woman presenting with a solid pelvic mass, normal tumor markers and no ascites...
September 2023: Case Reports in Women's Health
https://read.qxmd.com/read/37554166/a-pregnant-woman-with-a-giant-bilateral-parietal-hemangiopericytoma-underwent-multiple-surgeries-and-radiotherapy-a-case-report-and-literature-review
#36
Yingxi Wu, Yafei Xue, Xinqi Wang, Junting Li, Yan Qu, Tianzhi Zhao
Intracranial hemangiopericytoma is a rare invasive tumor originating from mesenchymal fibroblasts and is prone to local recurrence and distant metastasis. This study reports a case of a 27-year-old woman who presented with severe headache, nausea and vomiting for two weeks at thirty-three weeks of gestation. Cranial magnetic resonance imaging (MRI) demonstrated a giant lesion in the bilateral parietal lobe with a size of 5.12x9.19x6.03 cm and severe edema in the surrounding brain tissue. The patient underwent four operations and 3 gamma knife radiosurgery procedures and is recovering well now...
2023: Frontiers in Oncology
https://read.qxmd.com/read/37530348/infantile-congenital-anaplastic-intracranial-solitary-fibrous-tumor-hemangiopericytoma-a-case-report-with-brief-literature-review
#37
Mohapatra Debahuti, Lenka Anasuya, Deo R Chandra, Das Prateek
Solitary fibrous tumor/hemangiopericytoma (SFT/HPC) is a rare primary central nervous system (CNS) tumor, included in the World Health Organization (WHO) 2016 classification. Very few cases have been described in the literature so far, especially the infantile type. It is a mesenchymal tumor of the fibroblastic type, characterized by the fusion of NAB 2 and STAT 6 genes. A 10-month-old boy presented to our neurosurgery department with complaints of increasing head circumference since 1 month of age. The magnetic resonance imaging (MRI) showed a space-occupying lesion measuring 8...
2023: Indian Journal of Pathology & Microbiology
https://read.qxmd.com/read/37520395/combined-treatments-with-microballoon-catheters-and-multiple-cryoablation-probes-for-shoulder-subclavian-soft-tissue-hemangiopericytoma-a-case-report
#38
Renato Argirò, Giorgio Ciccarese, Leonardo Vattermoli, Sara Crociati, Vincenzo Iannibelli, Valentina Forte, Daniele Morosetti, Roberto Floris
We describe a case of a 65-year-old woman affected by hemangiopericytoma/solitary fibrous tumor of the right shoulder-subclavian region. Hemangiopericytoma/solitary fibrous tumor is a rare tumor of uncertain malignancy. She reports shoulder pain and inability to abduct the arm and elevate the shoulder. Imaging showed erosion of the scapula. The patient underwent 5 sessions of "on demand" embolization in the previous 2 years scheduled for recurrence of symptoms-swelling of tissues. Further 2 treatments were achieved through embolization via 2 different microballoon catheter combined with percutaneous cryoablation with 5 probes...
September 2023: Radiology Case Reports
https://read.qxmd.com/read/37492853/a-rare-case-of-intracranial-solitary-fibrous-tumor-that-is-still-alive-after-multiple-surgical-resections-a-case-report-and-review-of-the-literature
#39
YiMeng Gao, Yan Xu, RuiZhi Xie, YouBi Shen, DaoJin Xue, Zheng Zhen, JingJing Lu, Tao Huang, ZiZhuang Peng
A Solitary Fibrous Tumor (SFT) is a rare, aggressive, and metastasis- and recurrence- prone mesenchymal tumor. In this case report and review, we describe a rare instance of intracranial SFT, discovered for the first time. It was discovered in 2008 and following total surgical removal, the pathology was categorized as hemangiopericytoma cell tumor (HPC) at the time by WHO tumor criteria. An imaging review 8 months after surgery revealed a tumor recurrence: combined radiation and gamma-knife therapy was continued throughout this time...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37482670/68ga-prostate-specific-membrane-antigen-pet-ct-in-imaging-of-hemangiopericytoma
#40
JOURNAL ARTICLE
Jolanta Kunikowska, Beata E Chrapko
Hemangiopericytoma is a mesenchymal neoplasm that derives from pericytes surrounding the capillaries presenting overexpression of PSMA, which can be a source of pitfall in 68Ga-PSMA-11 PET/CT. We reported 2 cases with recurrent hemangiopericytoma grade III with high expression of 68Ga-PSMA-11 in PET/CT. Based on the performed examination, one of them received targeted α-therapy with the IV injection of 225Ac-PSMA-617.
July 24, 2023: Clinical Nuclear Medicine
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