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Hemangiopericytoma

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https://www.readbyqxmd.com/read/29687253/real-time-intraoperative-contrast-enhanced-ultrasound-ceus-in-vascularized-spinal-tumors-a-technical-note
#1
Giuseppe Maria Della Pepa, Pier Paolo Mattogno, Giuseppe La Rocca, Giovanni Sabatino, Alessandro Olivi, Luca Ricciardi, Filippo Maria Polli
BACKGROUNDS: Intra-operative ultrasound (ioUS), and the recently introduced contrast-enhanced ultrasound (CEUS) demonstrated to be an extremely valuable tool in oncological cerebral neurosurgery. METHODS: The authors applied ioUS/CEUS techniques to spinal oncological surgery as showed in the illustrative case of a dorsal hemangiopericytoma. RESULTS AND CONCLUSIONS: ioUS and CEUS provide real-time information that proved useful in identifying both vascular and parenchymatous tumoral patterns, anatomical relations with nervous structure, plan surgical strategy, and identify residuals...
April 23, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29682136/metastatic-cervical-paravertebral-solitary-fibrous-tumor-detected-by-fluorodeoxyglucose-positron-emission-tomography-computed-tomography
#2
Hoiwan Cheung, Courtney Lawhn-Heath, Giselle Lopez, Maya Vella, Carina Mari Aparici
Solitary fibrous tumor/hemangiopericytomas (SFT/HPC) are soft tissue tumors that can arising from the abomen, pleura, head and neck, or extremities. We report an unusual case of recurrent hemangiopericytoma in a 67-year-old female presenting with a painless and palpable mass within her right posterior neck. Eight years after initial resection of the mass, a follow-up MRI showed multiple enlarging calvarial lesions. A whole body FDG-PET/CT revealed not only hypermetabolic calvarial lesions but also numerous hypermetabolic axillary node and osseous metastases...
April 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29682031/solitary-fibrous-tumors-of-the-orbit-and-central-nervous-system-a-case-series-analysis
#3
Marisa Brum, Hipólito Nzwalo, Edson Oliveira, Maria Rita Pelejão, Pedro Pereira, João Paulo Farias, José Pimentel
Introduction: Solitary fibrous tumor (SFT) is rarely diagnosed in clinical practice. Since its initial descriptions in the central nervous system (CNS) and the orbits, very few case reports and small case series have expanded their clinical and pathological characterization. We sought to describe a cases series of SFT from a single laboratory of neuropathology belonging to a tertiary university hospital. Methods: Retrospective clinical and histopathological description of eight cases of CNS and orbital SFT diagnosed over a 21-year period of time...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29675794/association-between-programmed-cell-death-ligand-1-expression-and-extracranial-metastasis-in-intracranial-solitary-fibrous-tumor-hemangiopericytoma
#4
Dai Kamamoto, Kentaro Ohara, Yohei Kitamura, Kazunari Yoshida, Yutaka Kawakami, Hikaru Sasaki
BACKGROUND: Intracranial solitary fibrous tumor/hemangiopericytoma (SFT/HPC) often shows extracranial metastasis, and treatment options are very limited. Immune-checkpoint molecules have not been studied well in SFT/HPCs, and their role in intracranial SFT/HPCs remains unclear. METHODS: We investigated the expression of programmed cell death-1 (PD-1), programmed cell death ligand-1 (PD-L1), and tumor-infiltrating lymphocytes (TIL) in 16 patients of intracranial SFT/HPC by immunohistochemistry to determine if correlation with prognosis exists...
April 19, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29629229/ambiguity-in-the-dural-tail-sign-on-mri
#5
Ramesh S Doddamani, Rajesh K Meena, Dattaraj Sawarkar
Background: Meningiomas give rise to the dural tail sign (DTS) on contrast-enhanced magnetic resonance imaging (CEMRI). The presence of DTS does not always qualify for a meningioma, as it is seen in only 60-72% of cases. This sign has been described in various other lesions like lymphomas, metastasis, hemangiopericytomas, schwannomas and very rarely glioblastoma multiforme (GBM). The characteristics of dural-based GBMs are discussed here, as only eleven such cases are reported in the literature till date...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29626688/the-houdini-tumor-a-case-report-and-literature-review-of-pregnancy-associated-meningiomas
#6
Vikram Chakravarthy, Brett Kaplan, Vadim Gospodarev, Hannah Myers, Kenneth De Los Reyes, Adina Achiriloaie
BACKGROUND: Meningiomas are common intracranial neoplasms of undetermined etiology. Accelerated growth during episodes of elevated serum estrogen and progesterone have been demonstrated in pregnant patients, as exhibited by an overexpression of estrogen or progesterone upon immunohistochemical analysis. This case report and literature review describes a case of complete meningioma regression in a postpartum patient. CASE DESCRIPTION: A 23-year-old female presented at 37 weeks of pregnancy with 1-month history of fluctuating severe left-sided headaches, periodic blurry vision, nausea and vomiting...
April 4, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29600523/grading-of-meningeal-solitary-fibrous-tumors-hemangiopericytomas-analysis-of-the-prognostic-value-of-the-marseille-grading-system-in-a-cohort-of-132-patients
#7
Nicolas Macagno, Rob Vogels, Romain Appay, Carole Colin, Karima Mokhtari, Benno Küsters, Pieter Wesseling, Dominique Figarella-Branger, Uta Flucke, Corinne Bouvier
The finding that meningeal solitary fibrous tumors (SFTs) and meningeal hemangiopericytomas (HPCs) are both characterized by NAB2-STAT6 gene fusion has pushed their inclusion in the WHO 2016 Classification of tumors of the central nervous system (CNS) as different manifestations of the same entity. Given that the clinical behavior of the CNS SFT/HPC spectrum ranges from benign to malignant, it is presently unclear whether the grading criteria are still adequate. Here, we present the results of a study that analyzed the prognostic value of an updated version of the Marseille Grading System (MGS) in a retrospectively assembled cohort of 132 primary meningeal SFTs/HPCs with nuclear overexpression of STAT6...
March 30, 2018: Brain Pathology
https://www.readbyqxmd.com/read/29595682/salvage-preoperative-embolization-of-an-infratemporal-solitary-fibrous-tumor-a-case-report-with-review-of-the-literature
#8
Kabalane Yammine, Haydar A Nasser, Usama Hadi, Mohamad Ali Natout, Vicky Najjar, Claude Tayar
RATIONALE: Head and Neck Solitary fibrous tumors (SFT) are very rare. They could be misdiagnosed as hemangiopericytomas (HPC). PATIENT CONCERNS: We report a 60 y o lady presenting with sinonasal mass, causing recurrent profuse bleeding. DIAGNOSES: Hemangioperocytomas versus SFT were among the differentials, according to Radiological studies. Upon Biopsy, the diagnosis of SFT has been adopted. INTERVENTIONS: Salvage pre-operative embolization resulted in bleeding control, bridging the patient to surgery...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29566950/biphenotypic-sinonasal-sarcoma-a-series-of-six-cases-with-evaluation-of-role-of-%C3%AE-catenin-immunohistochemistry-in-differential-diagnosis
#9
Aanchal Kakkar, Madhu Rajeshwari, Pirabu Sakthivel, Mehar C Sharma, Suresh C Sharma
INTRODUCTION: Biphenotypic sinonasal sarcoma (BSNS) is a recently described mesenchymal tumor exclusive to the sinonasal region. It is a low grade sarcoma, displaying evidence of myogenic and neural differentiation. Role of β-catenin immunohistochemistry in distinguishing it from its morphological mimics is not well-established. We conducted this study to identify cases of BSNS from our archives, and to examine immunopositivity for β-catenin in them as well as in its close differential diagnosis...
April 2018: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/29555080/non-islet-cell-tumour-hypoglycaemia-nicth-about-a-series-of-6-cases
#10
Arnaud Jannin, Stéphanie Espiard, Kanza Benomar, Christine Do Cao, Bénédicte Mycinski, Henri Porte, Michèle D'Herbomez, Nicolas Penel, Marie-Christine Vantyghem
The purpose of this study was to analyse the characteristics of 6 patients managed in a university hospital between 1996 and 2016 for non-islet cell tumor hypoglycemia (NICTH), a form of hypoglycaemia due to the paraneoplastic secretion of IGF-2 or its related substances. RESULTS: Three of these 6 patients (50%), aged over 69 years, including 2 with acromegaloid phenotype, presented with a pleural solitary fibrous tumor (SFT), with median diameter 20 cm (interquartile range, 12.5-20.5) with a low median SUV (3...
March 16, 2018: Annales D'endocrinologie
https://www.readbyqxmd.com/read/29551003/surveillance-for-metastatic-hemangiopericytoma-solitary-fibrous-tumors-systematic-literature-review-on-incidence-predictors-and-diagnosis-of-extra-cranial-disease
#11
REVIEW
Tarini Ratneswaren, Florence Rosie Avila Hogg, Mathew Joseph Gallagher, Keyoumars Ashkan
BACKGROUND: Intracranial hemangiopericytomas (HPC) and solitary fibrous tumors (SFTs) (HPC-SFT) are rare vascular tumors that resemble meningioma on imaging and predominantly affect young adults. HPC-SFT have a high rate of local recurrence with well-known propensity for extracranial metastases. This provides clinical dilemmas frequently encountered in oncology: (i) How should these patients be monitored long term? (ii) Which primary tumors are more likely to metastasize? OBJECTIVES: This systematic review aims to identify the incidence, common locations and time to presentation of extra-cranial metastases of HPC-SFT...
March 17, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29531582/value-of-sstr2a-and-claudin-1-in-differentiating-meningioma-from-schwannoma-and-hemangiopericytoma
#12
Shady E Anis, Mira Lotfalla, Muhammad Zain, Nora N Kamel, Ahmed A Soliman
BACKGROUND: The distinction between meningioma, schwannoma and solitary fibrous tumour/ hemangiopericytoma can be challenging in some cases. This study evaluates the expression of Somatostatin receptor 2A (SSTR2A) and Claudin-1 in these different tumours. MATERIAL AND METHODS: Thirty-five cases of meningioma, 10 cases of intracranial schwannoma and 10 cases of hemangiopericytoma were assessed. The immunohistochemical expression of SSTR2A and Claudin-1 was evaluated and scored according to the percentage of immunostained tumour cells (0: 1+, 2+ and 3)...
February 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29530746/myopericytoma-of-the-lip-a-case-report-of-this-rare-lesion
#13
Eric Strayer, Roger Throndson, Cecilia Clement, Keith McDaniel
Myopericytomas are rare benign tumors that show a distinctive, concentric perivascular proliferation of oval to spindle-shaped myoid-appearing cells that are predominantly arranged concentrically around thin-walled vascular channels. These lesions are similar in histologic appearance to hemangiopericytomas, myofibromas, and glomus tumors. The myopericytoma is usually found in the distal extremities, but a handful of reports have shown the lesion to be present in the oral cavity. A review of the literature to date shows only 4 other reported cases of myopericytomas occurring in the lips...
February 19, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29521591/solitary-fibrous-tumor-hemangiopericytoma-treatment-results-based-on-the-2016-who-classification
#14
Kyoung Su Sung, Ju Hyung Moon, Eui Hyun Kim, Seok-Gu Kang, Se Hoon Kim, Chang-Ok Suh, Sun Ho Kim, Kyu-Sung Lee, Won Seok Chang, Jong Hee Chang
OBJECTIVE Solitary fibrous tumor/hemangiopericytoma (SFT/HPC) is a new combined entity for which a soft-tissue-type grading system, ranging from grades I to III, has been introduced in the 2016 WHO classification of tumors of the CNS. The results of the treatment of this new disease entity require evaluation. METHODS The authors retrospectively reevaluated the pathological findings and medical records of patients with SFT/HPC. This study included 60 patients (27 men and 33 women, median age 42.5 years, range 13-69 years) treated at Severance Hospital between February 1981 and February 2016...
March 9, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29509373/combined-use-of-mr-pet-and-5-ala-for-neurosurgical-management-of-recurrent-multiple-malignant-hemangiopericytomas
#15
Doortje C Engel, Simone Peraio, Sotirios Bisdas, Jens Schittenhelm, Marcos Tatagiba
No abstract text is available yet for this article.
March 6, 2018: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29486569/-cor-occidere-a-novel-strategy-of-targeting-the-tumor-core-by-radiosurgery-in-a-radio-and-chemo-resistant-intracranial-hemangiopericytoma
#16
You Quan Li, Eu Tiong Chua, Kevin L M Chua, Melvin L K Chua
Intracranial hemangiopericytomas (HPC) are chemotherapy- and radiotherapy (RT)-resistant. Here, we report on a novel stereotactic radiosurgery (SRS) technique-"Cor Occidere" (Latin), as a potential strategy of overcoming radioresistance of HPC. A 36-year old female presented to our clinic for consideration of a 3rd-course of RT for her recurrent cavernous sinus HPC, following previous cranial RT at 13 and 5 years prior, and a failed 9 months trial of bevacizumab/temozolomide. The tumor-adjacent brain stem and carotid artery risked substantial damage given the cumulative RT doses to these organs...
February 2018: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/29482421/multifocal-cytokeratin-expression-in-a-dedifferentiated-solitary-fibrous-tumor-with-heterologous-rhabdomyosarcomatous-differentiation-a-challenging-diagnosis
#17
David Creytens, Liesbeth Ferdinande, Jo Van Dorpe
We report the case of a dedifferentiated solitary fibrous tumor with heterologous rhabdomyosarcomatous differentiation in a 74-year-old male presenting with a rapidly growing, large soft tissue tumoral mass in the gluteal muscles of the right hip. Dedifferentiation in solitary fibrous tumor had not been recognized until very recently and is an extremely rare phenomenon in this tumor type. In the present case, the diagnosis of dedifferentiated solitary fibrous tumor was difficult because of the absence of areas of conventional solitary fibrous tumor with a predominantly poorly differentiated, anaplastic tumor component in the incision biopsy composed of heterogeneous areas with small blue round cell (Ewing sarcoma-like), rhabdoid, epithelioid, and pleomorphic morphology...
February 1, 2018: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29427152/solitary-fibrous-tumor-hemangiopericytoma-of-the-central-nervous-system-a-population-based-study
#18
Connor J Kinslow, Samuel S Bruce, Ali I Rae, Sameer A Sheth, Guy M McKhann, Michael B Sisti, Jeffrey N Bruce, Adam M Sonabend, Tony J C Wang
The World Health Organization (WHO) classification of tumors of the central nervous system (CNS) was recently updated, restructuring solitary fibrous tumor (SFT) and hemangiopericytoma (HPC) into one combined entity. This is the first population-based study to examine outcomes of SFT/HPC based on the new WHO guidelines. The Surveillance, Epidemiology, and End Results (SEER) database (1998-2013) was queried to examine age-adjusted incidence and prognostic factors associated with overall survival in 416 surgically resected cases...
February 9, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29425741/patterns-of-care-and-outcomes-of-postoperative-radiation-for-intracranial-hemangiopericytoma-in-united-states-hospitals
#19
Anna Lee, Baho Sidiqi, Arthur Wang, Joseph Safdieh, David Schreiber
OBJECTIVE: Several small (<100 patients) studies have been suggestive of a survival benefit associated with postoperative radiation for intracranial hemangiopericytoma. Given the rarity of this disease, we sought to examine the patterns of care and outcomes of this tumor in the National Cancer Database (NCDB). PATIENTS AND METHODS: We accessed the NCDB to identify patients with intracranial hemangiopericytoma between 2004-2012. Patients were categorized by surgical status, postoperative radiation usage, and location (meningeal or brain parenchyma)...
February 5, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29423351/hemangiopericytoma-in-the-olfactory-groove-a-rare-and-unusual-presentation
#20
Raghav Gupta, Justin M Moore, Kai Miller, Griffith R Harsh
Intracranial hemangiopericytomas (HPCs) are solitary fibrous tumors of the smooth muscle and the mesenchymal origin. While meningiomas located within the olfactory groove are common, an HPC in this location has never been reported previously. Here we describe the rare presentation of a differentiated HPC masquerading as an olfactory groove meningioma in a 33-year-old female presenting with the progressive headaches, anosmia, and visual field disturbances. Following resection, the histopathological analysis confirmed a grade II HPC...
November 25, 2017: Curēus
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