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cognitive bias modification

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https://www.readbyqxmd.com/read/28329674/%C3%AE-arrestin2-couples-metabotropic-glutamate-receptor-5-to-neuronal-protein-synthesis-and-is-a-potential-target-to-treat-fragile-x
#1
Laura J Stoppel, Benjamin D Auerbach, Rebecca K Senter, Anthony R Preza, Robert J Lefkowitz, Mark F Bear
Synaptic protein synthesis is essential for modification of the brain by experience and is aberrant in several genetically defined disorders, notably fragile X (FX), a heritable cause of autism and intellectual disability. Neural activity directs local protein synthesis via activation of metabotropic glutamate receptor 5 (mGlu5), yet how mGlu5 couples to the intracellular signaling pathways that regulate mRNA translation is poorly understood. Here, we provide evidence that β-arrestin2 mediates mGlu5-stimulated protein synthesis in the hippocampus and show that genetic reduction of β-arrestin2 corrects aberrant synaptic plasticity and cognition in the Fmr1(-/y) mouse model of FX...
March 21, 2017: Cell Reports
https://www.readbyqxmd.com/read/28299526/interpretation-bias-training-in-depressed-adolescents-near-and-far-transfer-effects
#2
Joelle LeMoult, Natalie Colich, Jutta Joormann, Manpreet K Singh, Caitlin Eggleston, Ian H Gotlib
Depressed adolescents are characterized by negative interpretation biases. Although investigators have used cognitive bias modification for interpretation (CBM-I) to experimentally manipulate interpretation biases in depressed adults, the near- and far-transfer effects are not well understood in adolescents diagnosed with Major Depressive Disorder (MDD). In this study, we extend previous research by investigating the near- and far-transfer effects of 6 sessions of Positive versus Neutral CBM-I on independent measures of interpretation bias (near-transfer effects) and on attention biases and clinical symptoms (far-transfer effects) in a sample of adolescents with MDD (n = 46)...
March 15, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28287798/a-randomized-clinical-trial-targeting-anxiety-sensitivity-for-patients-with-suicidal-ideation
#3
Norman B Schmidt, Aaron M Norr, Nicholas P Allan, Amanda M Raines, Daniel W Capron
OBJECTIVE: Anxiety sensitivity (AS) is a well-established transdiagnostic risk factor for anxiety and mood psychopathology including suicide. A variety of interventions using cognitive-behavioral skills as well as cognitive bias modification (CBM) suggest that AS can be quickly and effectively reduced in nonclinical and nontreatment seeking samples. However, it is unclear whether AS reduction protocols will have efficacy for more severe clinical samples. Moreover, the combination of cognitive-behavioral techniques with CBM focused on changing interpretation bias (CBM-I) related to AS has not been evaluated...
March 13, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28242729/abandoning-and-modifying-one-action-plan-for-alternatives
#4
REVIEW
Joo-Hyun Song
Visual scenes are often complex and crowded with many different objects. To interact effectively, we must choose one object at a time as a goal for action. Certain external cues can act as a stop signal, quickly cancelling an ongoing action. Less recognized are internal signals. These can come from recent experience, anticipated action outcomes, cognitive states, and when attention is captured by a salient object. These signals elevate one action plan over alternatives and can quickly modify an initial choice...
April 19, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28221057/-understanding-the-neural-basis-of-cognitive-bias-modification-as-a-clinical-treatment-for-depression-correction-to-eguchi-et-al-2016
#5
(no author information available yet)
Reports an error in "Understanding the neural basis of cognitive bias modification as a clinical treatment for depression" by Akihiro Eguchi, Daniel Walters, Nele Peerenboom, Hannah Dury, Elaine Fox and Simon Stringer (Journal of Consulting and Clinical Psychology, Advanced Online Publication, Dec 19, 2016, np). In the article, there was an error in the Discussion section's first paragraph for Implications and Future Work. The in-text reference citation for Penton-Voak et al. (2013) was incorrectly listed as "Blumenfeld, Preminger, Sagi, and Tsodyks (2006)"...
March 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28170102/enhancement-of-self-conducted-exposure-for-ocd-using-cognitive-bias-modification-a-case-study
#6
Sadia Najmi, Nader Amir
The psychological treatment of choice for obsessive-compulsive disorder (OCD) is exposure and response prevention (ERP). However, the training required for practitioners to be proficient in delivering ERP is not readily available, thereby rendering the treatment inaccessible to most patients. Self-directed ERP (sERP) programs designed to increase the accessibility of ERP have not proven effective, perhaps because patients find it difficult to comply with exposure exercises without the guidance of a clinician...
February 7, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28095313/prefrontal-mediation-of-emotion-regulation-in-social-anxiety-disorder-during-laughter-perception
#7
Benjamin Kreifelts, Carolin Brück, Thomas Ethofer, Jan Ritter, Lena Weigel, Michael Erb, Dirk Wildgruber
Social anxiety disorder (SAD) is characterized by negatively biased perception of social cues and deficits in emotion regulation. While negatively biased perception is thought to maintain social anxiety, emotion regulation represents an ability necessary to overcome both biased perception and social anxiety. Here, we used laughter as a social threat in a functional magnetic resonance imaging (fMRI) study to identify cerebral mediators linking SAD with attention and interpretation biases and their modification through cognitive emotion regulation in the form of reappraisal...
February 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28073958/rudeness-and-medical-team-performance
#8
Arieh Riskin, Amir Erez, Trevor A Foulk, Kinneret S Riskin-Geuz, Amitai Ziv, Rina Sela, Liat Pessach-Gelblum, Peter A Bamberger
OBJECTIVES: Rudeness is routinely experienced by medical teams. We sought to explore the impact of rudeness on medical teams' performance and test interventions that might mitigate its negative consequences. METHODS: Thirty-nine NICU teams participated in a training workshop including simulations of acute care of term and preterm newborns. In each workshop, 2 teams were randomly assigned to either an exposure to rudeness (in which the comments of the patient's mother included rude statements completely unrelated to the teams' performance) or control (neutral comments) condition, and 2 additional teams were assigned to rudeness with either a preventative (cognitive bias modification [CBM]) or therapeutic (narrative) intervention...
February 2017: Pediatrics
https://www.readbyqxmd.com/read/28055119/a-pilot-randomized-controlled-trial-of-cognitive-bias-modification-to-reduce-fear-of-breast-cancer-recurrence
#9
Wendy G Lichtenthal, Geoffrey W Corner, Elizabeth T Slivjak, Kailey E Roberts, Yuelin Li, William Breitbart, Stephanie Lacey, Malwina Tuman, Katherine N DuHamel, Victoria S Blinder, Courtney Beard
BACKGROUND: The most common, persistent concern among survivors of breast cancer is the fear that their disease will return, yet to the authors' knowledge, few interventions targeting fear of cancer recurrence (FCR) have been developed to date. The current pilot study examined the feasibility, acceptability, and preliminary efficacy of a home-delivered cognitive bias modification intervention to reduce FCR. The intervention, called Attention and Interpretation Modification for Fear of Breast Cancer Recurrence (AIM-FBCR), targeted 2 types of cognitive biases (ie, attention and interpretation biases)...
January 5, 2017: Cancer
https://www.readbyqxmd.com/read/28013069/cognitive-bias-modification-and-cbt-as-early-interventions-for-adolescent-social-and-test-anxiety-two-year-follow-up-of-a-randomized-controlled-trial
#10
Eva de Hullu, B Esther Sportel, Maaike H Nauta, Peter J de Jong
BACKGROUND AND OBJECTIVES: This two-year follow-up study evaluated the long-term outcomes of two early interventions that aimed at reducing social and test anxiety in young adolescents at risk for developing social anxiety disorder. METHODS: In this RCT, moderately socially anxious adolescents (N=240, mean age 13.6 years) were randomly assigned to a 10-week internet-based multifaceted cognitive bias modification training (CBM), a 10-week school-based cognitive behavioral group training (CBT), or a no-intervention control condition...
November 25, 2016: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/27991805/understanding-the-neural-basis-of-cognitive-bias-modification-as-a-clinical-treatment-for-depression
#11
Akihiro Eguchi, Daniel Walters, Nele Peerenboom, Hannah Dury, Elaine Fox, Simon Stringer
[Correction Notice: An Erratum for this article was reported in Vol 85(3) of Journal of Consulting and Clinical Psychology (see record 2017-07144-002). In the article, there was an error in the Discussion section's first paragraph for Implications and Future Work. The in-text reference citation for Penton-Voak et al. (2013) was incorrectly listed as "Blumenfeld, Preminger, Sagi, and Tsodyks (2006)". All versions of this article have been corrected.] Objective: Cognitive bias modification (CBM) eliminates cognitive biases toward negative information and is efficacious in reducing depression recurrence, but the mechanisms behind the bias elimination are not fully understood...
December 19, 2016: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/27986741/cognitive-bias-modification-for-interpretation-with-and-without-prior-repetitive-negative-thinking-to-reduce-worry-and-rumination-in-generalised-anxiety-disorder-and-depression-protocol-for-a-multisession-experimental-study-with-an-active-control-condition
#12
Charlotte Krahé, Andrew Mathews, Jessica Whyte, Colette R Hirsch
INTRODUCTION: Worry and rumination are two forms of repetitive thinking characterised by their negative content and apparently uncontrollable nature. Although worry and rumination share common features and have been conceptualised as part of a transdiagnostic repetitive negative thinking (RNT) process, it remains unclear whether they share the same underlying cognitive mechanisms. This multisession experimental study investigates the tendency to make negative interpretations regarding ambiguous information as a cognitive mechanism underlying RNT...
December 16, 2016: BMJ Open
https://www.readbyqxmd.com/read/27931196/attentional-bias-modification-in-depression-through-gaze-contingencies-and-regulatory-control-using-a-new-eye-tracking-intervention-paradigm-study-protocol-for-a-placebo-controlled-trial
#13
Carmelo Vazquez, Ivan Blanco, Alvaro Sanchez, Richard J McNally
BACKGROUND: Attentional biases, namely difficulties both to disengage attention from negative information and to maintain it on positive information, play an important role in the onset and maintenance of the disorder. Recently, researchers have developed specific attentional bias modification (ABM) techniques aimed to modify these maladaptive attentional patterns. However, the application of current ABM procedures has yielded, so far, scarce results in depression due, in part, to some methodological shortcomings...
December 8, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27923780/attentional-bias-modification-with-serious-game-elements-evaluating-the-shots-game
#14
Wouter J Boendermaker, Soraya Sanchez Maceiras, Marilisa Boffo, Reinout W Wiers
BACKGROUND: Young adults often experiment with heavy use of alcohol, which poses severe health risks and increases the chance of developing addiction problems. In clinical patients, cognitive retraining of automatic appetitive processes, such as selective attention toward alcohol (known as "cognitive bias modification of attention," or CBM-A), has been shown to be a promising add-on to treatment, helping to prevent relapse. OBJECTIVE: To prevent escalation of regular use into problematic use in youth, motivation appears to play a pivotal role...
December 6, 2016: JMIR Serious Games
https://www.readbyqxmd.com/read/27917364/cognitive-remediation-and-bias-modification-strategies-in-mood-and-anxiety-disorders
#15
Alexandra K Gold, Rebecca E Montana, Louisa G Sylvia, Andrew A Nierenberg, Thilo Deckersbach
PURPOSE OF REVIEW: Cognitive impairments and biases, which are prevalent in patients with mood and anxiety disorders, can affect quality of life and functioning. Traditional treatments are only insufficiently addressing these impairments and biases. We review the cognitive impairments and biases present in these disorders as well as treatments targeting these domains. RECENT FINDINGS: Interventions aimed at improving cognitive impairments and biases may help improve cognitive deficits and overall functioning in patients with mood and anxiety disorders...
December 2016: Current Behavioral Neuroscience Reports
https://www.readbyqxmd.com/read/27866085/cognitive-bias-modification-of-interpretation-in-children-with-social-anxiety-disorder
#16
Faith Orchard, Adela Apetroaia, Kiri Clarke, Cathy Creswell
Negative (or a lack of positive) interpretation of ambiguous social situations has been hypothesised to maintain social anxiety disorder in children, yet there is currently limited evidence to support this. Cognitive Bias Modification of Interpretation (CBM-I) provides a means to explore the causal influence of interpretation bias on social anxiety disorder, and has been associated with a reduction in social anxiety symptoms in adults. Seven to twelve year old children with a diagnosis of social anxiety disorder completed CBM-I training, adapted from materials designed for socially anxious children in the community, or no training...
January 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/27829693/practicing-emotionally-biased-retrieval-affects-mood-and-establishes-biased-recall-a-week-later
#17
Janna N Vrijsen, Paula T Hertel, Eni S Becker
Cognitive Bias Modification (CBM) can yield clinically relevant results. Only few studies have directly manipulated memory bias, which is prominent in depression. In a new approach to CBM, we sought to simulate or oppose ruminative processes by training the retrieval of negative or positive words. Participants studied positive and negative word pairs (Swahili cues with Dutch translations). In the positive and negative conditions, each of the three study trials was followed by a cued-recall test of training-congruent translations; a no-practice condition merely studied the pairs...
2016: Cognitive Therapy and Research
https://www.readbyqxmd.com/read/27809880/investigating-the-cost-effectiveness-of-attention-bias-modification-abm-for-outpatients-with-major-depressive-disorder-mdd-a-randomized-controlled-trial-protocol
#18
Gina R A Ferrari, Eni S Becker, Filip Smit, Mike Rinck, Jan Spijker
BACKGROUND: Despite the range of available, evidence-based treatment options for Major Depressive Disorder (MDD), the rather low response and remission rates suggest that treatment is not optimal, yet. Computerized attention bias modification (ABM) trainings may have the potential to be provided as cost-effective intervention as adjunct to usual care (UC), by speeding up recovery and bringing more patients into remission. Research suggests, that a selective attention for negative information contributes to development and maintenance of depression and that reducing this negative bias might be of therapeutic value...
November 3, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27790791/a-clinical-trial-with-combined-transcranial-direct-current-stimulation-and-alcohol-approach-bias-retraining
#19
Tess E den Uyl, Thomas E Gladwin, Mike Rinck, Johannes Lindenmeyer, Reinout W Wiers
Two studies showed an improvement in clinical outcomes after alcohol approach bias retraining, a form of Cognitive Bias Modification (CBM). We investigated whether transcranial direct current stimulation (tDCS) could enhance effects of CBM. TDCS is a neuromodulation technique that can increase neuroplasticity and has previously been found to reduce craving. One hundred alcohol-dependent inpatients (91 used for analysis) were randomized into three experimental groups in a double-blind parallel design. The experimental group received four sessions of CBM while receiving 2 mA of anodal tDCS over the dorsolateral prefrontal cortex (DLPFC)...
October 27, 2016: Addiction Biology
https://www.readbyqxmd.com/read/27714985/development-of-an-evidence-based-fall-risk-assessment-tool-and-evaluation-of-interrater-reliability-and-nurses-perceptions-of-the-tool-s-clarity-and-usability
#20
Miki Higaonna, Maki Enobi, Shizuka Nakamura
AIM: To develop and test interrater reliability of an evidence-based fall risk assessment tool for nurses and to investigate how nurses perceived the clarity and usability of the tool. METHODS: In phase 1, an evidence-based fall risk assessment tool was developed based on a literature review and expert discussion. The finalized tool assessed 11 risk factors and comprised 23 items. In phase 2, reliability testing was done. Two nurses out of a possible 125 participating nurses independently assessed each participating patient on admission with the assessment tool...
October 7, 2016: Japan Journal of Nursing Science: JJNS
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