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https://www.readbyqxmd.com/read/29452852/reduction-of-patient-radiation-dose-with-a-new-organ-based-dose-modulation-technique-for-thoraco-abdominopelvic-computed-tomography-ct-liver-dose-right-index
#1
M Fillon, S Si-Mohamed, P Coulon, A Vuillod, P Klahr, L Boussel
PURPOSE: To evaluate the radiation dose reduction, image quality and diagnostic confidence with thoraco-abdominopelvic computed tomography (TACT) using a new organ based dose modulation system (liver dose right index [Liver DRI]), compared to TACT using a standard automatic exposure control adjusting mA according to attenuation. METHODS: A total of 37 patients who had two TACT examinations on 2 different CT scanners, one using standard automatic exposure control (combination of a DoseRight automatic current selection and Z modulation) and one using Liver DRI were included...
February 13, 2018: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/29452703/validation-of-the-eighth-edition-of-the-american-joint-committee-on-cancer-staging-system-for-ampulla-of-vater-cancer
#2
Sung Joo Kim, Soyeon An, Hyo Jeong Kang, Joo Young Kim, Min Ah Jang, Jae Hoon Lee, Ki-Byung Song, Dae Wook Hwang, HyungJun Cho, Song Cheol Kim, Eunsil Yu, Seung-Mo Hong
BACKGROUND: The American Joint Committee on Cancer recently proposed the eighth edition of cancer staging system. Validation studies are required to evaluate the prognostic stratification of ampulla of Vater cancer patients. METHODS: In the study, 369 operatively resected patients with ampullary cancers were grouped based on the eighth T (T1a, limited to sphincter of Oddi; T1b, invasion to duodenal submucosa; T2, invasion to duodenal proper muscle; T3a, invasion to pancreas ≤0...
February 13, 2018: Surgery
https://www.readbyqxmd.com/read/29451364/the-prevalence-of-celiac-disease-in-adult-chinese-patients-with-diarrhea-predominant-irritable-bowel-syndrome-of-china-a-prospective-controlled-cohort-study
#3
Guanjun Kou, Jing Guo, Xiuli Zuo, Changqing Li, Chao Liu, Rui Ji, Han Liu, Xiao Wang, Yanqing Li
BACKGROUND: Celiac disease (CD) is a chronic inflammatory enteropathy with a symptom spectrum similar to that of irritable bowel syndrome (IBS). CD is a common, but largely undiagnosed, condition in Western countries. However, it is extremely rare among Chinese people, and few studies have evaluated its prevalence in China. OBJECTIVE: To determine the prevalence of CD in IBS patients diagnosed using the Rome III criteria in North China. METHODS: This was a single-center, prospective, controlled cohort study performed in Qilu Hospital involving 246 IBS patients and 246 healthy controls...
February 16, 2018: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29451295/evaluation-of-hif-1%C3%AE-and-inos-in-ischemia-reperfusion-gastric-model-bioimpedance-histological-and-immunohistochemical-analyses
#4
Eduardo Peña-Mercado, Mario Garcia-Lorenzana, Elena Arechaga-Ocampo, Claudia H González-De la Rosa, Nohra E Beltran
Gastrointestinal ischemia/reperfusion (I/R) generates pathological alterations that could lead to death. Early ischemic damage markers could be used to guide therapy and improve outcomes. AIM: To relate hypoxia-inducible factor 1α (HIF-1α) activation and inducible nitric oxide synthase (iNOS) expression to gastric impedance changes due to I/R damage. METHODS: Experimental animals were randomly distributed into 3 groups: control, ischemia (30 min) and I/R (60 min)...
February 16, 2018: Histology and Histopathology
https://www.readbyqxmd.com/read/29447966/molecular-insights-on-the-interaction-and-preventive-potential-of-epigallocatechin-3-gallate-in-celiac-disease
#5
Ricardo Dias, Natércia F Brás, Iva Fernandes, Maria Pérez-Gregório, Nuno Mateus, Victor Freitas
Celiac Disease (CD) is now recognized as a worldwide epidemic. Although a gluten free diet usually induces clinical improvements within days or weeks, adhering to this routine is still troublesome. Therefore, new solutions are needed for quality-of-life improvement of CD patients. The present work intends to bring molecular and thermodynamic insights on the ability of green tea epigalhocatechin-3-gallate (EGCG) to interact and modulate the bioavailability of a major CD immunodominant peptide (32-mer). Characterization of peptide binding was assessed by means of both 1D and 2D 1 H NMR experiments, ITC and Molecular Dynamics simulations...
February 12, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29446669/segmental-arterial-mediolysis-abdominal-imaging-of-and-disease-course-in-111-patients
#6
Sailen G Naidu, Christine O Menias, Rahmi Oklu, Robert S Hines, Kinan Alhalabi, Gerges Makar, Fadi E Shamoun, Stanislav Henkin, Robert D McBane
OBJECTIVE: The purpose of this study is to identify the imaging characteristics of segmental arterial mediolysis (SAM) at presentation and establish the longitudinal course of disease. MATERIALS AND METHODS: We retrospectively identified patients with SAM at a single institution from 2000 through 2015. Diagnosis was based on published guidelines with multidisciplinary consensus. Imaging studies obtained at initial evaluation were reviewed to evaluate imaging findings and vascular territory distribution...
February 15, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29439526/the-effect-of-oligofructose-enriched-inulin-on-faecal-bacterial-counts-and-microbiota-associated-characteristics-in-celiac-disease-children-following-a-gluten-free-diet-results-of-a-randomized-placebo-controlled-trial
#7
Natalia Drabińska, Elżbieta Jarocka-Cyrta, Lidia Hanna Markiewicz, Urszula Krupa-Kozak
Celiac disease (CD) is associated with intestinal microbiota alterations. The administration of prebiotics could be a promising method of restoring gut homeostasis in CD. The aim of this study was to evaluate the effect of prolonged oligofructose-enriched inulin (Synergy 1) administration on the characteristics and metabolism of intestinal microbiota in CD children following a gluten-free diet (GFD). Thirty-four paediatric CD patients (mean age 10 years; 62% females) on a GFD were randomized into two experimental groups receiving Synergy 1 (10 g/day) or placebo (maltodextrin; 7 g/day) for 3 months...
February 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29435875/a-prospective-study-to-evaluate-the-role-of-duodenal-bulb-biopsy-in-the-diagnosis-of-celiac-disease
#8
Bhanwar Singh Dhandhu, Gaurav Kumar Gupta, Shashank J Wanjari, Nidhi Sharma, Sandeep Nijhawan
BACKGROUND: Celiac disease (CeD) requires a biopsy from the small intestine to confirm the diagnosis. Conventionally, duodenal bulb (D1) was avoided as a biopsy site due to histological confounding factors at this site. However, sometimes, the bulb mucosa is the only affected site. The aim of the present study was to assess changes in duodenal bulb histology and compare it to distal duodenal histology and to analyze whether the addition of duodenal bulb biopsy increases the diagnostic yield of the CeD...
February 13, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29435874/a-tandem-approach-of-ttga-testing-a-new-approach-for-celiac-disease-screening
#9
EDITORIAL
Hetty J Bontkes, Chris J J Mulder
No abstract text is available yet for this article.
February 13, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29435751/impact-of-anatomical-position-of-the-pancreas-on-postoperative-complications-and-drain-amylase-concentrations-after-laparoscopic-distal-gastrectomy-for-gastric-cancer
#10
Koshi Kumagai, Naoki Hiki, Souya Nunobe, Satoshi Kamiya, Masahiro Tsujiura, Satoshi Ida, Manabu Ohashi, Toshiharu Yamaguchi, Takeshi Sano
BACKGROUND: Laparoscopic surgery for gastric cancer requires traction or compression of the pancreas, with the extent depending on the anatomical position of the pancreas. This study investigated the impact of the position of the pancreas on postoperative complications and drain amylase concentrations after laparoscopic distal gastrectomy (LDG). METHODS: Gastric cancer patients who underwent LDG were assessed retrospectively. The following anatomical parameters were measured retrospectively in preoperative computed tomography sagittal projections: the length of the vertical line between the pancreas and the aorta (P-A length), representing the height of the slope looking down the celiac artery from the top of the pancreas, and the angle between a line drawn from the upper border of the pancreas to the root of the celiac artery and the aorta (UP-CA angle), representing the steepness of the slope...
February 12, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29435314/mucosal-healing-and-the-risk-of-serious-infections-in-patients-with-celiac-disease
#11
Louise Emilsson, Benjamin Lebwohl, Peter Hr Green, Joseph A Murray, Karl Mårild, Jonas F Ludvigsson
Background: Patients with celiac disease (CD) are at increased risk of certain infections, but it is unknown if mucosal healing influences this risk. Methods: We collected data on 29,096 individuals with CD (equal to villous atrophy) through Sweden's 28 pathology departments undergoing biopsy 1969-2008. Through the Swedish Patient Register we obtained information on any infection and specifically sepsis, streptococcal infection, influenza, Clostridium difficile , herpes zoster and pneumococcal infection up until December 2009...
February 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29435186/prevalence-of-celiac-disease-in-patients-with-down-syndrome-a-meta-analysis
#12
Yang Du, Ling-Fei Shan, Zong-Ze Cao, Jin-Chao Feng, Yong Cheng
Background: The association between Down syndrome and celiac disease has been reported by many studies. However, the prevalence of celiac disease (CD) in Down syndrome (DS) varies considerably across studies (from 0 % to 19 %). The aim of this study was to use meta-analysis to exam the prevalence of CD in patients with DS. Methods: A systematic search of English articles from Pubmed, Web of Science and CNKI without year limitation. Data were extracted by two independent observers and pooled using a random effects model by the Comprehensive Meta-Analysis Version 2 software...
January 12, 2018: Oncotarget
https://www.readbyqxmd.com/read/29431403/mildly-elevated-liver-transaminase-levels-causes-and-evaluation
#13
Robert C Oh, Thomas R Hustead, Syed M Ali, Matthew W Pantsari
Mild, asymptomatic elevations (less than five times the upper limit of normal) of alanine transaminase and aspartate transaminase levels are common in primary care. It is estimated that approximately 10% of the U.S. population has elevated transaminase levels. An approach based on the prevalence of diseases that cause asymptomatic transaminase elevations can help clinicians efficiently identify common and serious liver disease. The most common causes of elevated transaminase levels are nonalcoholic fatty liver disease and alcoholic liver disease...
December 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/29430886/endovascular-treatment-of-para-anastomotic-aneurysms-after-open-abdominal-aortic-surgery
#14
Konstantinos Spanos, Tilo Kölbel, George Kouvelos, Nikolaos Tsilimparis, Sebastian E Debus, Athanasios D Giannoukas
INTRODUCTION: The repair of long-term complications of open abdominal aortic repair such as para-anastomotic aneurysm (PAA) and pseudoaneurysm (PSA) is very challenging. The aim of this study was to assess the outcomes of endovascular repair of PAA/PSA after previous open aortic surgery for aneurismal or occlusive disease. EVIDENCE ACQUISITION: A systematic review was undertaken; a search was performed (PRISMA) in MEDLINE, CENTRAL, Cochrane databases and key references of all studies of endovascular treatment of PAA/PSA after open aortic surgery...
February 8, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29426626/antituberculosis-treatment-in-a-patient-with-celiac-disease
#15
Alicia Cerezo Lajas, José Antonio Caminero Luna, María Del Carmen Rodríguez Guzmán, Javier de Miguel Díez
No abstract text is available yet for this article.
February 6, 2018: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/29425234/targeted-liquid-chromatography-tandem-mass-spectrometry-to-quantitate-wheat-gluten-using-well-defined-reference-proteins
#16
Kathrin Schalk, Peter Koehler, Katharina Anne Scherf
Celiac disease (CD) is an inflammatory disorder of the upper small intestine caused by the ingestion of storage proteins (prolamins and glutelins) from wheat, barley, rye, and, in rare cases, oats. CD patients need to follow a gluten-free diet by consuming gluten-free products with gluten contents of less than 20 mg/kg. Currently, the recommended method for the quantitative determination of gluten is an enzyme-linked immunosorbent assay (ELISA) based on the R5 monoclonal antibody. Because the R5 ELISA mostly detects the prolamin fraction of gluten, a new independent method is required to detect prolamins as well as glutelins...
2018: PloS One
https://www.readbyqxmd.com/read/29424803/clozapine-associated-with-microscopic-colitis-in-the-setting-of-biopsy-proven-celiac-disease
#17
Kelly Holz, Natalie A Martos, Russell L Margolis
No abstract text is available yet for this article.
February 8, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29424384/hematological-and-biometric-traits-of-tuvira-gymnotus-inaequilabiatus-valenciennes-1839-gymnotiformes-gymnotidae-from-the-brazilian-pantanal
#18
Robson A Rodrigues, Eduarda S Silva, Sandriely F Marcondes, Gizela M Galindo, Gustavo G DE Oliveira, Alda I DE Souza, José Ragusa-Netto, Carlos E Fernandes
This study describes the hematological and biometric characteristics of male and female Gymnotus species from the Pantanal, Mato Grosso do Sul state, Brazil. Fifty adult specimens of Gymnotus inaequilabiatus were weighed, measured, and then euthanized. Blood was collected by puncturing the celiac mesenteric vein to determine the hematocrit, hemoglobin content, number of erythrocytes, mean corpuscular volume, mean corpuscular hemoglobin concentration, glucose level, absolute value of leukocytes, and relative value of leukocytes and thrombocytes...
February 1, 2018: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29422338/linear-%C3%AE-1%C3%A2-%C3%A2-%C3%A2-6-d-glucan-from-bifidobacterium-bifidum-bim-%C3%B0-733d-is-low-molecular-mass-biopolymer-with-unique-immunochemical-properties
#19
Elena P Kiseleva, Konstantin I Mikhailopulo, Evelina L Zdorovenko, Yuriy A Knirel, Galina I Novik
Role of microorganisms in induction of/protection from autoimmune diseases is proven though molecular mechanisms and bacterial/viral/yeast biopolymers responsible for these effects are in the research stage. Autoantobodies (AAbs) to thyroid peroxidase (anti-TPO) and thyroglobulin (anti-Tg) as well as AAbs to transglutaminase 2 (anti-TG2) and antibodies to gliadins (anti-gliadins) are serological markers of autoimmune thyroid disease and celiac disease, respectively, and players in pathogenesis of these autoimmune diseases...
December 20, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/29422261/risk-of-colorectal-adenomas-in-patients-with-celiac-disease-a-systematic-review-and-meta-analysis
#20
J Lasa, A Rausch, I Zubiaurre
INTRODUCTION AND AIMS: Whether celiac disease increases the risk of presenting with colorectal adenoma or not, has not been extensively evaluated. This question becomes relevant when considering early screening methods in patients with the disease. The aim of our article was to determine the risk of colorectal adenomas in celiac disease patients. MATERIALS AND METHODS: A computer-assisted search of the MEDLINE-Pubmed, EMBASE, LILACS, Cochrane Library, and Google Scholar databases was carried out, encompassing the time frame of 1966 to December 2016...
February 5, 2018: Revista de Gastroenterología de México
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