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https://www.readbyqxmd.com/read/29149474/interventions-for-old-world-cutaneous-leishmaniasis
#1
REVIEW
Julio Heras-Mosteiro, Begoña Monge-Maillo, Mariona Pinart, Patricia Lopez Pereira, Emely Garcia-Carrasco, Pedro Campuzano Cuadrado, Ana Royuela, Irene Mendez Roman, Rogelio López-Vélez
BACKGROUND: Cutaneous leishmaniasis, caused by a parasitic infection, is considered one of the most serious skin diseases in many low- and middle-income countries. Old World cutaneous leishmaniasis (OWCL) is caused by species found in Africa, Asia, the Middle East, the Mediterranean, and India. The most commonly prescribed treatments are antimonials, but other drugs have been used with varying success. As OWCL tends to heal spontaneously, it is necessary to justify the use of systemic and topical treatments...
November 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29149469/cuffed-versus-uncuffed-endotracheal-tubes-for-general-anaesthesia-in-children-aged-eight-years-and-under
#2
REVIEW
Flavia A De Orange, Rebeca Gac Andrade, Andrea Lemos, Paulo Sgn Borges, José N Figueiroa, Pete G Kovatsis
BACKGROUND: Since the introduction of endotracheal intubation in paediatrics, uncuffed endotracheal tubes (ETTs) have been the standard of care for children under eight years old, based on the presumption that complications, particularly postoperative stridor, are higher with cuffed ETTs. The major disadvantages of uncuffed ETTs cited for this shift in procedure include the difficulty in achieving tidal volumes due to leakage around an uncuffed ETT. To seal the airway adequately, uncuffed tubes may need to be exchanged for another tube with a larger diameter, which sometimes requires several attempts before the appropriate size is found...
November 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29133274/gender-differences-in-the-impact-of-anemia-on-subclinical-myocardial-damage-and-cardiovascular-mortality-in-the-general-population-the-yamagata-takahata-study
#3
Yuki Honda, Tetsu Watanabe, Yoichiro Otaki, Harutoshi Tamura, Satoshi Nishiyama, Hiroki Takahashi, Takanori Arimoto, Tetsuro Shishido, Takuya Miyamoto, Yoko Shibata, Tsuneo Konta, Ryo Kawasaki, Makoto Daimon, Yoshiyuki Ueno, Takeo Kato, Takamasa Kayama, Isao Kubota
BACKGROUND: Anemia has been shown to worsen cardiovascular diseases. However, it is unclear whether there is a gender difference in the impact of anemia on subclinical myocardial damage and cardiovascular mortality in the general population. METHODS: A prospective cohort study was conducted in a community based on annual health checks. Serum heart-type fatty acid binding protein (H-FABP) levels, which is a marker for myocardial damage, and blood counts were measured at baseline in subjects without previous cardiovascular diseases (n=3111)...
November 10, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29113966/cystic-fibrosis-newborn-screening-outcome-of-infants-with-normal-sweat-tests
#4
Claire Edmondson, Christopher Grime, Ammani Prasad, Jacqui Cowlard, Chinedu E C Nwokoro, Gary Ruiz, Colin Wallis, Ian M Balfour-Lynn
Newborn babies positively screened for cystic fibrosis (CF) (high serum immunoreactive trypsin (IRT) with DNA analysis) are referred for a diagnostic sweat test, which may be normal (sweat chloride <30 mmol/L). Unless two gene mutations are identified during Newborn screening (NBS), the babies are discharged from follow-up. We wished to check that none had subsequently developed symptoms suggestive of CF. We retrospectively reviewed patient notes and contacted general practitioners of all babies with a negative sweat test, conducted in one of the four paediatric specialist CF centres in London, over the first 6 years of screening in South East England...
November 7, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29079032/association-between-accumulation-of-advanced-glycation-end-products-and-hearing-impairment-in-community-dwelling-older-people-a-cross-sectional-sukagawa-study
#5
Kakuya Niihata, Sei Takahashi, Noriaki Kurita, Nobuyuki Yajima, Kenji Omae, Shingo Fukuma, Takayuki Okano, Yukio Nomoto, Koichi Omori, Shunichi Fukuhara
OBJECTIVES: The experimental studies suggested the hypothesis that the accumulation of advanced glycation end-products (AGEs) could induce hearing impairment. The purpose of this study is to examine the hypothesis among elderly people using an epidemiologic approach. DESIGN: Cross-sectional study. SETTING: Sukagawa City, Fukushima, Japan. PARTICIPANTS: A total of 270 residents aged 75 years or over without dementia, who participated in a health check-up conducted in 2015...
October 24, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29067145/electroacupuncture-therapy-for-auricular-paresthesia
#6
Masaya Fukushima, Hinata Sakuraba, Nobuko Shiraiwa, Shonosuke Matsushita
Background: The great auricular nerve (GAN) provides sensory innervation to the skin around the auricle. Although disorder of this nerve has been reported, great auricular neuralgia, as reported by Blumenthal in 1992, is uncommon. The authors report a case of auricular paresthesia that responded well to electroacupuncture treatment (EAT). Case: A man in his 60s was consulted in the clinic after a 6-month history of experiencing tingling sensations of the skin around the auricle. General degenerative deformity of the cervical spine was observed using computed radiography scans and magnetic resonance imaging; tactile hyperesthesia in the skin of the GAN area was also noted...
October 1, 2017: Medical Acupuncture
https://www.readbyqxmd.com/read/29063827/subcutaneous-injection-of-adalimumab-trial-compared-with-control-sciatic-a-randomised-controlled-trial-of-adalimumab-injection-compared-with-placebo-for-patients-receiving-physiotherapy-treatment-for-sciatica
#7
Nefyn H Williams, Alison Jenkins, Nia Goulden, Zoe Hoare, Dyfrig A Hughes, Eifiona Wood, Nadine E Foster, David A Walsh, Dawn Carnes, Valerie Sparkes, Elaine M Hay, John Isaacs, Kika Konstantinou, Dylan Morrissey, Jaro Karppinen, Stephane Genevay, Clare Wilkinson
BACKGROUND: Biological treatments such as adalimumab (Humira(®); AbbVie Ltd, Maidenhead, UK) are antibodies targeting tumour necrosis factor alpha, released from ruptured intervertebral discs, which might be useful in sciatica. Recent systematic reviews concluded that they might be effective, but that a definitive randomised controlled trial was needed. Usual care in the NHS typically includes a physiotherapy intervention. OBJECTIVES: To test whether or not injections of adalimumab plus physiotherapy are more clinically effective and cost-effective than injections of saline plus physiotherapy for patients with sciatica...
October 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29052014/predictive-validity-of-a-service-setting-based-measure-to-identify-infancy-mental-health-problems-a-population-based-cohort-study
#8
Janni Ammitzbøll, Lau Caspar Thygesen, Bjørn E Holstein, Anette Andersen, Anne Mette Skovgaard
Measures to identify infancy mental health problems are essential to guide interventions and reduce the risk of developmental psychopathology in early years. We investigated a new service-setting-based measure the Copenhagen Infant Mental Health Screening (CIMHS) within the general child health surveillance by community health nurses (CHN). The study population of 2973 infants was assessed by CIMHS at age 9-10 months. A subsample of 416 children was examined at age 1½ years, using parent interviews including the Child Behavior Checklist (CBCL 1½-5), Check List of Autism and Toddlers (CHAT), Infant-Toddler Symptom Checklist (ITSCL), and the Bayley Scales of Infant and Toddler Development (BSID) and observations of behavior, communication, and interaction...
October 20, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29040336/characteristics-of-private-partners-in-chiranjeevi-yojana-a-public-private-partnership-to-promote-institutional-births-in-gujarat-india-lessons-for-universal-health-coverage
#9
Veena Iyer, Kristi Sidney, Rajesh Mehta, Dileep Mavalankar, Ayesha De Costa
BACKGROUND: The Chiranjeevi Yojana (CY) is a Public-Private-Partnership between the state and private obstetricians in Gujarat, India, since 2007. The state pays for institutional births of the most vulnerable households (below-poverty-line and tribal) in private hospitals. An innovative remuneration package has been designed to disincentivise unnecessary cesareans. This study examines characteristics of private facilities which participated in the program. METHODS: We conducted a cross-sectional survey of all facilities which had conducted any births between June 2012 and April 2013 in three districts...
2017: PloS One
https://www.readbyqxmd.com/read/29016823/the-effect-of-cardiorespiratory-fitness-assessment-in-preventive-health-checks-a-randomised-controlled-trial
#10
Kirsten Høj, Mette Vinther Skriver, Helle Terkildsen Maindal, Bo Christensen, Annelli Sandbæk
Background: Poor cardiorespiratory fitness (CRF) increases morbidity and mortality risks. Routine CRF assessment in clinical practice has thus been advocated, but little is known about the effect. In this study, we investigated the effect of CRF assessment on CRF in a preventive health check programme. Methods: We used a randomised design, in which we invited 4153 middle-aged adults and included 2201 participants who received a preventive health check with CRF assessment (intervention) or without CRF assessment (control)...
July 18, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28990535/voluntary-medical-male-circumcision-to-prevent-hiv-in-tanah-papua-indonesia-field-trial-to-assess-acceptability-and-feasibility
#11
M Ridwan Ansari, Elan Lazuardi, Frank Stephen Wignall, Constant Karma, Sylvanus A Sumule, Siti Nadia, Robert Magnani
BACKGROUND: Relatively little attention has been directed to the significant HIV prevention role that voluntary medical male circumcision (VMMC) can play in populations with moderate levels of HIV prevalence. One such location is Tanah Papua, Indonesia, which in 2013 had a general population HIV prevalence of 2.3% concentrated among indigenous Papuans (2.9% prevalence), very few of whom are circumcised. This article reports the findings of an implementation research study assessing the acceptability and feasibility of introducing VMMC for HIV prevention...
October 5, 2017: Current HIV Research
https://www.readbyqxmd.com/read/28986645/assessing-the-utility-of-a-distress-screening-tool-at-capturing-sexual-concerns-in-a-gyne-oncology-follow-up-clinic
#12
Lauren M Walker, Majken P Villiger, John W Robinson
PURPOSE: Communication and assessment of sexual health within cancer care is poor despite high rates of sexual dysfunction in cancer survivors. Screening for distress programs have been implemented, as a standardized part of cancer care across Canada, with the aim of increasing identification and improving access to support. Alberta Health Services uses a general distress screening form, containing the Canadian Problem Checklist, which includes a list of possible problems, one of which is "intimacy/sexuality...
October 6, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28985958/a-scoping-review-of-evidence-based-interventions-available-to-parents-of-maltreated-children-ages-0-5-involved-with-child-welfare-services
#13
Ashley L Landers, Alan McLuckie, Robin Cann, Valerie Shapiro, Sarah Visintini, Bruce MacLaurin, Nico Trocmé, Michael Saini, Normand J Carrey
Parents referred to child welfare services for child maltreatment often struggle against chronic risk factors including violence, substance abuse, mental health concerns, and poverty, which impinge upon their ability to be sensitive caregivers. The first line of intervention within the child welfare context is to modify parenting behavior. This scoping review comprehensively surveyed all available literature to map the extent and range of research activity around the types of interventions available within a child welfare context to parents of infants and toddlers (0-5 years of age), to identify the facilitators and/or barriers to the uptake of interventions, and to check that interventions match the risk factors faced by parents...
October 3, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28977687/professional-structural-and-organisational-interventions-in-primary-care-for-reducing-medication-errors
#14
REVIEW
Hanan Khalil, Brian Bell, Helen Chambers, Aziz Sheikh, Anthony J Avery
BACKGROUND: Medication-related adverse events in primary care represent an important cause of hospital admissions and mortality. Adverse events could result from people experiencing adverse drug reactions (not usually preventable) or could be due to medication errors (usually preventable). OBJECTIVES: To determine the effectiveness of professional, organisational and structural interventions compared to standard care to reduce preventable medication errors by primary healthcare professionals that lead to hospital admissions, emergency department visits, and mortality in adults...
October 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28957371/predictors-of-all-cause-mortality-among-514-866-participants-from-the-korean-national-health-screening-cohort
#15
Choonghyun Ahn, Yunji Hwang, Sue K Park
BACKGROUND: There is not enough evidence regarding how information obtained from general health check-ups can predict individual mortality based on long-term follow-ups and large sample sizes. This study evaluated the applicability of various health information and measurements, consisting of self-reported data, anthropometric measurements and laboratory test results, in predicting individual mortality. METHODS: The National Health Screening Cohort included 514,866 participants (aged 40-79 years) who were randomly selected from the overall database of the national health screening program in 2002-2003...
2017: PloS One
https://www.readbyqxmd.com/read/28943803/primary-hyperoxaluria-detected-by-bone-marrow-biopsy-case-report
#16
F Nachite, M Dref, A Fakhri, H Rais
BACKGROUND: Primary hyperoxaluria is a rare disease with an estimated prevalence of 1 to 3 cases per million. It is due to a hepatic enzyme deficiency responsible for an endogenous overproduction of oxalate. Oxalate crystals commonly deposit in the kidney and more rarely in bone marrow. The literature has reported, to the best of our knowledge, only two cases of hyperoxaluria diagnosed by bone marrow biopsy and our case is the only one that does not show radiological bone lesions. CASE PRESENTATION: A young 22 year old chronic hemodialysis patient with nephrocalcinosis...
2017: BMC Clinical Pathology
https://www.readbyqxmd.com/read/28926565/a-snp-panel-and-online-tool-for-checking-genotype-concordance-through-comparing-qr-codes
#17
Yonghong Du, Joshua S Martin, John McGee, Yuchen Yang, Eric Yi Liu, Yingrui Sun, Matthias Geihs, Xuejun Kong, Eric Lingfeng Zhou, Yun Li, Jie Huang
In the current precision medicine era, more and more samples get genotyped and sequenced. Both researchers and commercial companies expend significant time and resources to reduce the error rate. However, it has been reported that there is a sample mix-up rate of between 0.1% and 1%, not to mention the possibly higher mix-up rate during the down-stream genetic reporting processes. Even on the low end of this estimate, this translates to a significant number of mislabeled samples, especially over the projected one billion people that will be sequenced within the next decade...
2017: PloS One
https://www.readbyqxmd.com/read/28922089/the-jolly-fat-effect-in-middle-aged-korean-women
#18
Gyeyoon Yim, Younjhin Ahn, Juhee Cho, Yoosoo Chang, Seungho Ryu, Joong-Yeon Lim, Hyun-Young Park
BACKGROUND: It has been hypothesized that depression and obesity are bi-directionally associated, and when overweight people appear to show a lower risk of depression, this supports the "Jolly Fat" hypothesis. The aim of this study was to examine the "Jolly Fat" hypothesis in middle-aged women in Korea, by different perceived stress levels. METHODS: We performed a cross-sectional study of 44 to 56 aged Korean women (n = 2201) who underwent a health check-up program at the healthcare centers of Kangbuk Samsung Hospital (Seoul and Suwon centers) in Korea...
November 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28898390/comprehensive-geriatric-assessment-for-older-adults-admitted-to-hospital
#19
REVIEW
Graham Ellis, Mike Gardner, Apostolos Tsiachristas, Peter Langhorne, Orlaith Burke, Rowan H Harwood, Simon P Conroy, Tilo Kircher, Dominique Somme, Ingvild Saltvedt, Heidi Wald, Desmond O'Neill, David Robinson, Sasha Shepperd
BACKGROUND: Comprehensive geriatric assessment (CGA) is a multi-dimensional, multi-disciplinary diagnostic and therapeutic process conducted to determine the medical, mental, and functional problems of older people with frailty so that a co-ordinated and integrated plan for treatment and follow-up can be developed. This is an update of a previously published Cochrane review. OBJECTIVES: We sought to critically appraise and summarise current evidence on the effectiveness and resource use of CGA for older adults admitted to hospital, and to use these data to estimate its cost-effectiveness...
September 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28886739/an-australian-general-practice-based-strategy-to-improve-chronic-disease-prevention-and-its-impact-on-patient-reported-outcomes-evaluation-of-the-preventive-evidence-into-practice-cluster-randomised-controlled-trial
#20
Mark Fort Harris, Sharon M Parker, John Litt, Mieke van Driel, Grant Russell, Danielle Mazza, Upali W Jayasinghe, Jane Smith, Chris Del Mar, Riki Lane, Elizabeth Denney-Wilson
BACKGROUND: Implementing evidence-based chronic disease prevention with a practice-wide population is challenging in primary care. METHODS: PEP Intervention practices received education, clinical audit and feedback and practice facilitation. Patients (40‑69 years) without chronic disease from trial and control practices were invited to participate in baseline and 12 month follow up questionnaires. Patient-recalled receipt of GP services and referral, and the proportion of patients at risk were compared over time and between intervention and control groups...
September 8, 2017: BMC Health Services Research
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