keyword
MENU ▼
Read by QxMD icon Read
search

Anal cancer review

keyword
https://www.readbyqxmd.com/read/29158102/human-papillomavirus-types-from-infection-to-cancer-in-the-anus-according-to-sex-and-hiv-status-a-systematic-review-and-meta-analysis
#1
Chunqing Lin, Silvia Franceschi, Gary M Clifford
BACKGROUND: Data on carcinogenicity of human papillomavirus (HPV) types in the anus are needed to inform anal cancer prevention through vaccination and screening. This is particularly the case for people infected with HIV, who are at an increased risk of anal cancer. METHODS: We did a systematic review of studies published from January, 1986, to July, 2017, in MEDLINE, Embase, and the Cochrane Library on anal HPV infection, without any language restrictions. Eligible studies reported type-specific HPV prevalence by strata of cytopathological or histopathological anal diagnosis, sex, and HIV status...
November 17, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29149907/mapping-evidence-on-the-distribution-of-human-papillomavirus-related-cancers-in-sub-saharan-africa-scoping-review-protocol
#2
Bridget K M Lekoane, Tivani P Mashamba-Thompson, Themba G Ginindza
BACKGROUND: Despite the introduction of HPV vaccines, the incidence of HPV-related cancers (cervical, penile, anal, vulvar, vagina, head, and neck) in sub-Saharan Africa has been rising. The increasing incidence of these HPV-related cancers has been attributed to changes in lifestyle-related risk factors, most notably sexual behavior. The main objective of this study is to map evidence on the distribution of HIV-related cancers in sub-Saharan Africa (SSA). METHODS AND ANALYSIS: We will conduct a scoping review to explore, describe, and map literature on the distribution of HPV-related cancers in sub-Saharan Africa...
November 17, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29125801/laparoscopic-versus-open-restorative-proctocolectomy-for-familial-adenomatous-polyposis
#3
Fábio Guilherme Campos, Carlos Augusto Real Martinez, Mariane Gouveia Monteiro de Camargo, Daniele Menezes Cesconetto, Sérgio Carlos Nahas, Ivan Cecconello
PURPOSE: This study compared outcomes after laparoscopic (LAP) or conventional (open) total proctocolectomy with outcomes after ileal J-pouch anal anastomosis (IPAA) at a single institution. METHODS: Charts from 133 familial adenomatous polyposis patients (1997-2013) were reviewed. Demographic data (age, sex, color, American Society of Anesthesiologists [ASA] status, previous surgery, and body mass index) and surgical outcomes (length of stay, early and late morbidity, reoperation, and mortality rates) were compared among 63 patients undergoing IPAA...
November 10, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29114614/preoperative-radiation-dose-escalation-for-rectal-cancer-using-a-concomitant-boost-strategy-improves-tumor-downstaging-without-increasing-toxicity-a-matched-pair-analysis
#4
Jillian R Gunther, Awalpreet S Chadha, Ui Sup Shin, In Ja Park, Kiran V Kattepogu, Jonathan D Grant, David C Weksberg, Cathy Eng, Scott E Kopetz, Prajnan Das, Marc E Delclos, Harmeet Kaur, Dipen M Maru, John M Skibber, Miguel A Rodriguez-Bigas, Y Nancy You, Sunil Krishnan, George J Chang
Purpose: Pathologic complete response to neoadjuvant chemoradiation therapy (CRT) is associated with improved outcomes for patients with locally advanced rectal cancer (LARC). Increased response rates have been reported with higher radiation doses, but these studies often lack long-term outcome and/or toxicity data. We conducted a case-control analysis of patients with LARC who underwent definitive CRT to determine the efficacy and safety of intensified treatment with a concomitant boost (CB) approach...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29114593/quantitative-fdg-pet-ct-predicts-local-recurrence-and-survival-for-squamous-cell-carcinoma-of-the-anus
#5
Michael L Cardenas, Christopher R Spencer, Stephanie Markovina, Todd A DeWees, Thomas R Mazur, Ashley A Weiner, Parag J Parikh, Jeffrey R Olsen
Purpose: (18)F-fluorodeoxyglucose (FDG) positron emission tomography-(PET)/computed tomography (CT) imaging is used for staging and treatment planning of patients with anal cancer. Quantitative pre- and posttreatment metrics that are predictive of recurrence are unknown. We evaluated the association between pre- and posttreatment FDG-PET/CT parameters and outcomes for patients with squamous cell carcinoma of the anus (SCCA). Methods and materials: The records of 110 patients treated between 2003 and 2013 with definitive radiation therapy for SCCA were reviewed under an institutional review board-approved protocol...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29112562/initiation-of-a-transanal-total-mesorectal-excision-program-at-an-academic-training-program-evaluating-patient-safety-and-quality-outcomes
#6
Justin A Maykel, Uma R Phatak, Pasithorn A Suwanabol, Andrew T Schlussel, Jennifer S Davids, Paul R Sturrock, Karim Alavi
BACKGROUND: Short-term results have shown that transanal total mesorectal excision is safe and effective for patients with mid to low rectal cancers. Transanal total mesorectal excision is considered technically challenging; thus, adoption has been limited to a few academic centers in the United States. OBJECTIVE: The aim of this study is to describe outcomes after the initiation of a transanal total mesorectal excision program in the setting of an academic colorectal training program...
December 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29107432/-reconstruction-of-abdo-perineal-resection-by-taylor-flap-about-68-patients
#7
D Boccara, K SerroR, J Lefevre, M Mimoun, M Chaouat
PURPOSES: Healing after abdomino-perineal resection is often difficult, especially in patients who have undergone radiation therapy. Vaginal reconstruction is also an important issue for the women who undergo this surgery. We describe and analyze here our series of perineal reconstructions with modified Taylor flaps. Between 2010 and 2016, 68 patients (52 women, 16 men) with cancer of the anal canal (53), adenocarcinoma of the lower rectum (9), or other malignant neoplasms of the perineum underwent reconstruction with a rectus abdominis myocutaneous (RAM) flap with an inferior pedicle and an oblique skin paddle...
October 26, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/29100742/outcome-of-neoadjuvant-chemoradiation-in-mri-staged-locally-advanced-rectal-cancer-retrospective-analysis-of-123-chinese-patients
#8
Shing Fung Lee, Chi Leung Chiang, Francis Ann Shing Lee, Yiu Wah Wong, Chi Ming Poon, Frank Chi Sing Wong, Stewart Yuk Tung
BACKGROUND: For advanced rectal cancer with involved or threatened mesorectal fascia (MRF), current standard is pre-operative long course chemoradiotherapy (PLCRT) with either capecitabine or 5-fluorouracil (5-FU). However, few Chinese data on its clinical outcome are available, especially for those with pelvic MRI staging. METHODS: Between Jan-2009 and Oct-2014, 123 consecutive patients with biopsy proven adenocarcinoma of rectum, all with pelvic MRI staging, selected for PLCRT after multi-disciplinary team discussion were recruited...
November 1, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/29098433/effect-of-transanal-total-mesorectal-excision-for-rectal-cancer-comparison-of-short-term-outcomes-with-laparoscopic-and-open-surgeries
#9
Sharaf Karim Perdawood, Benjamin Sejr Thinggaard, Maya Xania Bjoern
OBJECTIVE: To compare short-term results of total mesorectal excision (TME) for mid and low rectal cancer, achieved by transanal (TaTME), laparoscopic (LaTME), and open (OpTME) approaches. BACKGROUND: The impact of TaTME on the surgical treatment of mid and low rectal cancer has yet to be clarified. METHODS: This is a case-matched study, based on data from a prospectively maintained database of patients who underwent TaTME from May 2015 to March 2017, and a retrospective chart review of patients who underwent LaTME and OpTME in the previous period...
November 2, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29027878/are-prophylactic-antibiotic-agents-indicated-in-anorectal-surgery-for-patients-with-human-immunodeficiency-virus
#10
Shaivi A Patel, Robert J Kucejko, Edward A Fazendin, Juan L Poggio
BACKGROUND: With increased survival among patients with human immunodeficiency virus (HIV), surgeons have been seeing more cases of anal dysplasia and cancer. There is, however, no data on the incidence of surgical site infections (SSIs) in HIV-positive patients undergoing elective anorectal procedures, nor on the administration of prophylactic antibiotic agents. We reviewed a HIV-positive population that has undergone elective anorectal biopsy of areas of dysplasia observed on office anoscopy to assess the need for antibiotic prophylaxis...
October 13, 2017: Surgical Infections
https://www.readbyqxmd.com/read/29026506/an-analysis-of-widely-viewed-youtube-videos-on-anal-cancer
#11
Corey H Basch, Aleksandar Kecojevic, Alyssa Berdnik, Valerie Cadorett, Charles E Basch
BACKGROUND: Rates of anal squamous cell carcinoma have increased over recent decades. The aim of this study was to describe characteristics of widely viewed YouTube videos about anal cancer. METHODS: A total of 57 videos were identified and reviewed. Videos were assessed and coded with respect to date uploaded, upload source, gender of presenter, number of views, length in minutes, number of likes and dislikes, and selected aspects of content. Each video was assessed to determine if the sole purpose of the video was to provide information regarding anal cancer or existed to serve another purpose...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28972796/pet-imaging-in-anal-canal-cancer-a-systematic-review-and-meta-analysis
#12
Aamer Mahmud, Raymond Poon, Derek Jonker
OBJECTIVE: The aim of this study was to systematically review the literature to synthesize and summarize the evidence surrounding the clinical utility of positron emission tomography (PET) imaging in patients with anal canal cancer. METHODS: The literature was searched using MEDLINE, EMBASE and Cochrane Database of Systematic Reviews databases. Studies comparing PET or PET/CT with conventional imaging in the staging, response evaluation and follow-up of anal canal cancer were deemed eligible for inclusion...
December 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28962572/impact-of-hpv-vaccination-health-gains-in-the-italian-female-population
#13
Andrea Marcellusi
BACKGROUND: Human papillomavirus (HPV) is the leading cause of cervical cancer and other malignant and benign neoplastic lesions. HPV vaccination has three potential goals: to prevent transmission, infection, and disease. At present, there are no available data about health consequences of HPV immunization in Italy. The aim of this study is to evaluate the effect of current HPV vaccination strategy in Italy. METHODS: A multistate morbidity-mortality model was developed to estimate the infection process in a theoretical cohort of Italian women...
September 29, 2017: Population Health Metrics
https://www.readbyqxmd.com/read/28959428/coincidence-or-not-a-rare-case-of-rectal-leiomyosarcoma-amidst-incidental-findings-of-anal-squamous-cell-carcinoma-case-presentation-and-literature-review
#14
Gosta Iwasiuk, Jason Nealy
Leiomyosarcoma accounts for only a small percentage of colorectal malignancies and remains a difficult disease to diagnose and treat. Here, we describe a case of leiomyosarcoma in a middle-age female first identified on colonoscopy. The cancer had invaded the posterior vaginal wall necessitating an abdominoperineal resection with partial vaginectomy and pelvic floor reconstruction with neovagina creation. Final pathologic analysis revealed invasion into the posterior vaginal wall without direct involvement of the vaginal squamous mucosa...
September 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28956458/9-valent-human-papillomavirus-vaccine-a-review-of-the-clinical-development-program
#15
Alain Luxembourg, Erin Moeller
The 9-valent human papillomavirus (9vHPV) vaccine covers the same HPV types (6/11/16/18) as the quadrivalent HPV (qHPV) vaccine and 5 additional cancer-causing types (31/33/45/52/58). Epidemiological studies indicate that the 9vHPV vaccine could prevent approximately 90% of cervical cancers, 70-85% of high-grade cervical dysplasia (precancers), 85-95% of HPV-related vulvar, vaginal, and anal cancers, and 90% of genital warts. Areas covered: Study design features and key findings from the 9vHPV vaccine clinical development program are reviewed...
October 9, 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28931234/the-evva-cohort-study-anal-and-cervical-type-specific-human-papillomavirus-prevalence-persistence-and-cytologic-findings-in-women-living-with-hiv
#16
Alexandra de Pokomandy, Elaina Kaufman, Christina de Castro, Marie-Hélène Mayrand, Ann N Burchell, Marina Klein, Louise Charest, Manon Auger, Sophie Rodrigues-Coutlée, François Coutlée
Background: The risk of anal cancer due to high-risk human papillomavirus (HR-HPV) is higher in women living with human immunodeficiency virus (HIV) than in the general population. We present findings of cervical and anal HPV and cytologic tests at baseline in the EVVA cohort study and HPV persistence data 6 months after baseline. Methods: Semiannual visits included questionnaires, chart reviews, cervical/anal cytologic and cervical/anal HPV testing for 2 years...
August 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28926109/role-of-viruses-in-gastrointestinal-cancer
#17
REVIEW
Habibollah Mirzaei, Hossein Goudarzi, Gita Eslami, Ebrahim Faghihloo
Gastrointestinal cancers are a global public health problem, which represent a vast majority of all cancer-caused deaths in both men and women. On the other hand, viral pathogens have been long implicated as etiological factors in the onset of certain human cancers, including gastrointestinal tumors. In this regard, Human Papilloma Virus (HPV), Epstein-Barr Virus (EBV), and John Cunningham Virus (JCV) have been more strongly suggested to be involved in gastrointestinal carcinogenesis; so that, the association of HPV with oropharyngeal and anal cancers and also the association of EBV with gastric cancer have been etiologically confirmed by epidemiological and experimental investigations...
September 19, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28918994/meaningful-methods-for-increasing-human-papillomavirus-vaccination-rates-an%C3%A2-integrative-literature-review
#18
Kristin Vollrath, Susan Thul, Jenny Holcombe
Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States and is a well-known cause of oropharyngeal, cervical, vaginal, vulvar, penile, and anal cancers. Despite the proven efficacy of the HPV vaccine, vaccination rates remain persistently low. Much literature has focused on attitudes toward the HPV vaccine; however, researchers have also investigated strategies clinicians can use to improve vaccination attitudes and acceptance. Such strategies include provider education, vaccine reminder/recall, and chart audit and feedback...
September 15, 2017: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/28918425/definitive-chemoradiotherapy-for-anal-carcinoma-long-term-results-based-on-consistent-time-to-event-endpoints
#19
Francesca De Felice, Maria Teresa Martinetti, Simone Orelli, Nadia Bulzonetti, Daniela Musio, Vincenzo Tombolini
AIM: To report the long-term results after definitive chemoradiotherapy (CRT) for anal carcinoma, using consistent time-to-event endpoints. METHODS AND MATERIALS: Anal carcinoma patient charts were reviewed. All patients received definitive CRT. Overall survival (OS), local failure-free survival (LFFS), locoregional failure-free survival (LRFFS), distant metastasis-free survival (DMFS), and anal dysfunction-free survival (ADFS) were estimated. RESULTS: In total, 65 patients were included...
September 16, 2017: Oncology
https://www.readbyqxmd.com/read/28898333/-usefulness-of-imaging-studies-in-prostate-cancer-analysis-of-241-patients
#20
Nagel Martínez M, Carlos Calvo, Álvaro Ibarra, Christian Ramos, Norman Zambrano
BACKGROUND: The role of staging studies in patients with prostate cancer (PCa) is a topic of discussion. AIM: To evaluate the usefulness of imaging studies in patients with prostate cancer. MATERIAL AND METHODS: We reviewed the pathology service records to identify patients with prostate cancer diagnosed between 2003 and 2013. We reviewed the electronic medical records of those patients identified as having a prostate cancer. Patients were grouped according D’amico’s classification of cancer dissemination risk...
May 2017: Revista Médica de Chile
keyword
keyword
13956
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"