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Adrian V Horodnic, Sorin Mazilu, Liviu Oprea
In order to explain informal payments in public health care services in Romania, this paper evaluates the relationship between extra payments or valuable gifts (apart from official fees) and the level of tolerance to corruption, as well as the socio-economic and spatial patterns across those individuals offering informal payments. To evaluate this, a survey undertaken in 2013 is reported. Using logistic regression analysis, the findings are that patients with a high tolerance to corruption, high socio-economic risk (those divorced, separated, or with other form of marital status, and those not working), and located in rural or less affluent areas are more likely to offer (apart from official fees) extra payments or valuable gifts for health care services...
March 15, 2018: International Journal of Health Planning and Management
Azam Peyvandipour, Nafiseh Saberian, Adib Shafi, Michele Donato, Sorin Draghici
Motivation: Identification of novel therapeutic effects for existing U.S. Food and Drug Administration (FDA)-approved drugs, drug repurposing, is an approach aimed to dramatically shorten the drug discovery process, which is costly, slow and risky. Several computational approaches use transcriptional data to find potential repurposing candidates. The main hypothesis of such approaches is that if gene expression signature of a particular drug is opposite to the gene expression signature of a disease, that drug may have a potential therapeutic effect on the disease...
March 9, 2018: Bioinformatics
Ionut Negoi, Mircea Beuran, Sorin Hostiuc, Ruxandra Irina Negoi, Yosuke Inoue
The surgeon dissecting the base of the mesenterium, around the superior mesenteric vein (SMV) and artery, is facing a complex tridimensional vascular anatomy and should be aware of the anatomical variants in this area. The aim of this systematic review is to propose a standardized terminology of the superior mesenteric vessels, with impact in colon and pancreatic resections. We conducted a systematic search in PubMed/MEDLINE and Google Scholar databases up to March 2017. Forty-five studies, involving a total of 6090 specimens were included in the present meta-analysis...
March 8, 2018: Scientific Reports
J William Schleifer, Sorin V Pislaru, Grace Lin, Brian D Powell, Raul Espinosa, Celeste Koestler, Trena Thome, Lynn Polk, Zhuo Li, Samuel J Asirvatham, Yong-Mei Cha
BACKGROUND: Pacing lead-related tricuspid regurgitation (TR), a recognized complication of ventricular pacing lead implantation, may be affected by lead position or diameter. OBJECTIVE: This study sought to determine the effect of ventricular pacing lead position and diameter on pacing lead-related TR. METHODS: A randomized, prospective trial compared pacing leads in the right ventricular apex (RVA), right ventricular mid septum (RVS), or left ventricle via the coronary sinus (LV-CS) in a 1:1:1 fashion...
February 26, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Sorin Hostiuc, Alin Moldoveanu, Ionuţ Negoi, Eduard Drima
Background: In the last years were published many epidemiological articles aiming to link driving under the influence of cannabis (DUIC) with the risk of various unfavorable traffic events (UTEs), with sometimes contradictory results. Aim: The primary objective of this study was to analyze whether there is a significant association between DUIC and UTEs. Materials and Methods: We used two meta-analytical methods to assess the statistical significance of the effect size: random-effects model and inverse variance heterogeneity model...
2018: Frontiers in Pharmacology
Guglielmo Stefanelli, Fabrizio Pirro, Alina Olaru, Giuseppe Danniballe, Clorinda Labia, Luca Weltert
OBJECTIVES: Information on the long-term safety, efficacy and durability of third-generation stentless aortic valves is lacking. METHODS: In this single-centre, single-surgeon retrospective observational study, between 2003 and 2015, consecutive, non-selected aortic valve replacement (AVR) patients were implanted with the LivaNova-Sorin Pericarbon Freedom™, a third-generation stentless aortic xenograft. Changes in clinical and echocardiographic parameters were examined, as were mortality, structural valve deterioration and reoperation, according to age at 5, 10 and 14 years...
February 21, 2018: Interactive Cardiovascular and Thoracic Surgery
Cristian Mihalea, Jildaz Caroff, Aymeric Rouchaud, Sorin Pescariu, Jacques Moret, Laurent Spelle
No abstract text is available yet for this article.
February 13, 2018: World Neurosurgery
Catalin Tiliscan, Victoria Arama, Raluca Mihailescu, Daniela Munteanu, Diana Gabriela Iacob, Cristina Popescu, Remulus Catana, Anca Negru, Alina Lobodan, Stefan Sorin Arama
BACKGROUND: Adiponectin and leptin are adipose tissue hormones that regulate important lipid and glucose metabolic pathways. Our objective was to evaluate the interplay of these hormones described by the adiponectin/leptin ratio (ALR) in correlation to lipid and carbohydrate metabolism parameters in nondiabetic HIV-infected patients during antiretroviral therapy (ART). MATERIALS AND METHODS: We enrolled consecutive nondiabetic patients with confirmed HIV infection, undergoing stable ART regimens for at least six months...
February 16, 2018: Endocrine Research
Sorin Claudiu Man, Valentina Sas, Cristina Schnell, Camelia Florea, Adelina Ţuţu, Ariana Szilágyi, Sergiu Belenes, Amalia Hebriştean, Anca Bonaţ, Claudia Cladovan, Cornel Aldea
Background and aims: Community-acquired pneumonia (CAP) is a both common and serious childhood infection. Antibiotic treatment guidelines help to reduce inadequate antibiotics prescriptions. Methods: We conducted a retrospective study at the Clinical Emergency Hospital for Children, 3rd Pediatric Clinic, Cluj-Napoca and Dr. Gavril Curteanu Clinical City Hospital, in Oradea. All patients discharged with a diagnosis of CAP between December 1, 2014 and February 28, 2015, were included in the study...
2018: Clujul Medical (1957)
Jacob C Jentzer, Nandan S Anavekar, Sunil V Mankad, Roger D White, Kianoush B Kashani, Gregory W Barsness, Alejandro A Rabinstein, Sorin V Pislaru
AIM: Reversible myocardial dysfunction is common after out-of-hospital cardiac arrest (OHCA). The aim of this study was to determine if changes on serial transthoracic echocardiography (TTE) can predict long-term mortality in OHCA subjects. METHODS: This is a single-center historical cohort study of OHCA subjects undergoing targeted temperature management who received >1 TTE during hospitalization. Two-dimensional and Doppler parameters of systolic and diastolic function were compared between paired TTE...
February 10, 2018: Resuscitation
T Aaltonen, V M Abazov, B Abbott, B S Acharya, M Adams, T Adams, J P Agnew, G D Alexeev, G Alkhazov, A Alton, S Amerio, D Amidei, A Anastassov, A Annovi, J Antos, G Apollinari, J A Appel, T Arisawa, A Artikov, J Asaadi, W Ashmanskas, A Askew, S Atkins, B Auerbach, K Augsten, A Aurisano, V Aushev, Y Aushev, C Avila, F Azfar, F Badaud, W Badgett, T Bae, L Bagby, B Baldin, D V Bandurin, S Banerjee, A Barbaro-Galtieri, E Barberis, P Baringer, V E Barnes, B A Barnett, P Barria, J F Bartlett, P Bartos, U Bassler, M Bauce, V Bazterra, A Bean, F Bedeschi, M Begalli, S Behari, L Bellantoni, G Bellettini, J Bellinger, D Benjamin, A Beretvas, S B Beri, G Bernardi, R Bernhard, I Bertram, M Besançon, R Beuselinck, P C Bhat, S Bhatia, V Bhatnagar, A Bhatti, K R Bland, G Blazey, S Blessing, K Bloom, B Blumenfeld, A Bocci, A Bodek, A Boehnlein, D Boline, E E Boos, G Borissov, D Bortoletto, M Borysova, J Boudreau, A Boveia, A Brandt, O Brandt, L Brigliadori, M Brochmann, R Brock, C Bromberg, A Bross, D Brown, E Brucken, X B Bu, J Budagov, H S Budd, M Buehler, V Buescher, V Bunichev, S Burdin, K Burkett, G Busetto, P Bussey, C P Buszello, P Butti, A Buzatu, A Calamba, E Camacho-Pérez, S Camarda, M Campanelli, F Canelli, B Carls, D Carlsmith, R Carosi, S Carrillo, B Casal, M Casarsa, B C K Casey, H Castilla-Valdez, A Castro, P Catastini, S Caughron, D Cauz, V Cavaliere, A Cerri, L Cerrito, S Chakrabarti, K M Chan, A Chandra, A Chapelain, E Chapon, G Chen, Y C Chen, M Chertok, G Chiarelli, G Chlachidze, K Cho, S W Cho, S Choi, D Chokheli, B Choudhary, S Cihangir, D Claes, A Clark, C Clarke, J Clutter, M E Convery, J Conway, M Cooke, W E Cooper, M Corbo, M Corcoran, M Cordelli, F Couderc, M-C Cousinou, C A Cox, D J Cox, M Cremonesi, D Cruz, J Cuevas, R Culbertson, J Cuth, D Cutts, A Das, N d'Ascenzo, M Datta, G Davies, P de Barbaro, S J de Jong, E De La Cruz-Burelo, F Déliot, R Demina, L Demortier, M Deninno, D Denisov, S P Denisov, M D'Errico, S Desai, C Deterre, K DeVaughan, F Devoto, A Di Canto, B Di Ruzza, H T Diehl, M Diesburg, P F Ding, J R Dittmann, A Dominguez, S Donati, M D'Onofrio, M Dorigo, A Driutti, A Drutskoy, A Dubey, L V Dudko, A Duperrin, S Dutt, M Eads, K Ebina, R Edgar, D Edmunds, A Elagin, J Ellison, V D Elvira, Y Enari, R Erbacher, S Errede, B Esham, H Evans, A Evdokimov, V N Evdokimov, S Farrington, A Fauré, L Feng, T Ferbel, J P Fernández Ramos, F Fiedler, R Field, F Filthaut, W Fisher, H E Fisk, G Flanagan, R Forrest, M Fortner, H Fox, J Franc, M Franklin, J C Freeman, H Frisch, S Fuess, Y Funakoshi, C Galloni, P H Garbincius, A Garcia-Bellido, J A García-González, A F Garfinkel, P Garosi, V Gavrilov, W Geng, C E Gerber, H Gerberich, E Gerchtein, Y Gershtein, S Giagu, V Giakoumopoulou, K Gibson, C M Ginsburg, G Ginther, N Giokaris, P Giromini, V Glagolev, D Glenzinski, O Gogota, M Gold, D Goldin, A Golossanov, G Golovanov, G Gomez, G Gomez-Ceballos, M Goncharov, O González López, I Gorelov, A T Goshaw, K Goulianos, E Gramellini, P D Grannis, S Greder, H Greenlee, G Grenier, Ph Gris, J-F Grivaz, A Grohsjean, C Grosso-Pilcher, S Grünendahl, M W Grünewald, T Guillemin, J Guimaraes da Costa, G Gutierrez, P Gutierrez, S R Hahn, J Haley, J Y Han, L Han, F Happacher, K Hara, K Harder, M Hare, A Harel, R F Harr, T Harrington-Taber, K Hatakeyama, J M Hauptman, C Hays, J Hays, T Head, T Hebbeker, D Hedin, H Hegab, J Heinrich, A P Heinson, U Heintz, C Hensel, I Heredia-De La Cruz, M Herndon, K Herner, G Hesketh, M D Hildreth, R Hirosky, T Hoang, J D Hobbs, A Hocker, B Hoeneisen, J Hogan, M Hohlfeld, J L Holzbauer, Z Hong, W Hopkins, S Hou, I Howley, Z Hubacek, R E Hughes, U Husemann, M Hussein, J Huston, V Hynek, I Iashvili, Y Ilchenko, R Illingworth, G Introzzi, M Iori, A S Ito, A Ivanov, S Jabeen, M Jaffré, E James, D Jang, A Jayasinghe, B Jayatilaka, E J Jeon, M S Jeong, R Jesik, P Jiang, S Jindariani, K Johns, E Johnson, M Johnson, A Jonckheere, M Jones, P Jonsson, K K Joo, J Joshi, S Y Jun, A W Jung, T R Junk, A Juste, E Kajfasz, M Kambeitz, T Kamon, P E Karchin, D Karmanov, A Kasmi, Y Kato, I Katsanos, M Kaur, R Kehoe, S Kermiche, W Ketchum, J Keung, N Khalatyan, A Khanov, A Kharchilava, Y N Kharzheev, B Kilminster, D H Kim, H S Kim, J E Kim, M J Kim, S H Kim, S B Kim, Y J Kim, Y K Kim, N Kimura, M Kirby, I Kiselevich, J M Kohli, K Kondo, D J Kong, J Konigsberg, A V Kotwal, A V Kozelov, J Kraus, M Kreps, J Kroll, M Kruse, T Kuhr, A Kumar, A Kupco, M Kurata, T Kurča, V A Kuzmin, A T Laasanen, S Lammel, S Lammers, M Lancaster, K Lannon, G Latino, P Lebrun, H S Lee, H S Lee, J S Lee, S W Lee, W M Lee, X Lei, J Lellouch, S Leo, S Leone, J D Lewis, D Li, H Li, L Li, Q Z Li, J K Lim, A Limosani, D Lincoln, J Linnemann, V V Lipaev, E Lipeles, R Lipton, A Lister, H Liu, Q Liu, T Liu, Y Liu, A Lobodenko, S Lockwitz, A Loginov, M Lokajicek, R Lopes de Sa, D Lucchesi, A Lucà, J Lueck, P Lujan, P Lukens, R Luna-Garcia, G Lungu, A L Lyon, J Lys, R Lysak, A K A Maciel, R Madar, R Madrak, P Maestro, R Magaña-Villalba, S Malik, S Malik, V L Malyshev, G Manca, A Manousakis-Katsikakis, J Mansour, L Marchese, F Margaroli, P Marino, J Martínez-Ortega, K Matera, M E Mattson, A Mazzacane, P Mazzanti, R McCarthy, C L McGivern, R McNulty, A Mehta, P Mehtala, M M Meijer, A Melnitchouk, D Menezes, P G Mercadante, M Merkin, C Mesropian, A Meyer, J Meyer, T Miao, F Miconi, D Mietlicki, A Mitra, H Miyake, S Moed, N Moggi, N K Mondal, C S Moon, R Moore, M J Morello, A Mukherjee, M Mulhearn, Th Muller, P Murat, M Mussini, J Nachtman, Y Nagai, J Naganoma, E Nagy, I Nakano, A Napier, M Narain, R Nayyar, H A Neal, J P Negret, J Nett, P Neustroev, H T Nguyen, T Nigmanov, L Nodulman, S Y Noh, O Norniella, T Nunnemann, L Oakes, S H Oh, Y D Oh, T Okusawa, R Orava, J Orduna, L Ortolan, N Osman, C Pagliarone, A Pal, E Palencia, P Palni, V Papadimitriou, N Parashar, V Parihar, S K Park, W Parker, R Partridge, N Parua, A Patwa, G Pauletta, M Paulini, C Paus, B Penning, M Perfilov, Y Peters, K Petridis, G Petrillo, P Pétroff, T J Phillips, G Piacentino, E Pianori, J Pilot, K Pitts, C Plager, M-A Pleier, V M Podstavkov, L Pondrom, A V Popov, S Poprocki, K Potamianos, A Pranko, M Prewitt, D Price, N Prokopenko, F Prokoshin, F Ptohos, G Punzi, J Qian, A Quadt, B Quinn, P N Ratoff, I Razumov, I Redondo Fernández, P Renton, M Rescigno, F Rimondi, I Ripp-Baudot, L Ristori, F Rizatdinova, A Robson, T Rodriguez, S Rolli, M Rominsky, M Ronzani, R Roser, J L Rosner, A Ross, C Royon, P Rubinov, R Ruchti, F Ruffini, A Ruiz, J Russ, V Rusu, G Sajot, W K Sakumoto, Y Sakurai, A Sánchez-Hernández, M P Sanders, L Santi, A S Santos, K Sato, G Savage, V Saveliev, M Savitskyi, A Savoy-Navarro, L Sawyer, T Scanlon, R D Schamberger, Y Scheglov, H Schellman, P Schlabach, E E Schmidt, M Schott, C Schwanenberger, T Schwarz, R Schwienhorst, L Scodellaro, F Scuri, S Seidel, Y Seiya, J Sekaric, A Semenov, H Severini, F Sforza, E Shabalina, S Z Shalhout, V Shary, S Shaw, A A Shchukin, T Shears, P F Shepard, M Shimojima, O Shkola, M Shochet, I Shreyber-Tecker, V Simak, A Simonenko, P Skubic, P Slattery, K Sliwa, J R Smith, F D Snider, G R Snow, J Snow, S Snyder, S Söldner-Rembold, H Song, L Sonnenschein, V Sorin, K Soustruznik, R St Denis, M Stancari, J Stark, N Stefaniuk, D Stentz, D A Stoyanova, M Strauss, J Strologas, Y Sudo, A Sukhanov, I Suslov, L Suter, P Svoisky, K Takemasa, Y Takeuchi, J Tang, M Tecchio, P K Teng, J Thom, E Thomson, V Thukral, M Titov, D Toback, S Tokar, V V Tokmenin, K Tollefson, T Tomura, D Tonelli, S Torre, D Torretta, P Totaro, M Trovato, Y-T Tsai, D Tsybychev, B Tuchming, C Tully, F Ukegawa, S Uozumi, L Uvarov, S Uvarov, S Uzunyan, R Van Kooten, W M van Leeuwen, N Varelas, E W Varnes, I A Vasilyev, F Vázquez, G Velev, C Vellidis, A Y Verkheev, C Vernieri, L S Vertogradov, M Verzocchi, M Vesterinen, M Vidal, D Vilanova, R Vilar, J Vizán, M Vogel, P Vokac, G Volpi, P Wagner, H D Wahl, R Wallny, M H L S Wang, S M Wang, J Warchol, D Waters, G Watts, M Wayne, J Weichert, L Welty-Rieger, W C Wester, D Whiteson, A B Wicklund, S Wilbur, H H Williams, M R J Williams, G W Wilson, J S Wilson, P Wilson, B L Winer, P Wittich, M Wobisch, S Wolbers, H Wolfmeister, D R Wood, T Wright, X Wu, Z Wu, T R Wyatt, Y Xie, R Yamada, K Yamamoto, D Yamato, S Yang, T Yang, U K Yang, Y C Yang, W-M Yao, T Yasuda, Y A Yatsunenko, W Ye, Z Ye, G P Yeh, K Yi, H Yin, K Yip, J Yoh, K Yorita, T Yoshida, S W Youn, G B Yu, I Yu, J M Yu, A M Zanetti, Y Zeng, J Zennamo, T G Zhao, B Zhou, C Zhou, J Zhu, M Zielinski, D Zieminska, L Zivkovic, S Zucchelli
The CDF and D0 experiments at the Fermilab Tevatron have measured the asymmetry between yields of forward- and backward-produced top and antitop quarks based on their rapidity difference and the asymmetry between their decay leptons. These measurements use the full data sets collected in proton-antiproton collisions at a center-of-mass energy of sqrt[s]=1.96  TeV. We report the results of combinations of the inclusive asymmetries and their differential dependencies on relevant kinematic quantities. The combined inclusive asymmetry is A_{FB}^{tt[over ¯]}=0...
January 26, 2018: Physical Review Letters
Sorin Buga, Chandana Banerjee, Jaroslava Salman, Marissa Cangin, Finly Zachariah, Bonnie Freeman
Patients with head and neck cancers (HNC) face multiple psychosocial and physical challenges that require multidisciplinary attention and care throughout their disease process. The psychoemotional symptoms may be triggered by cosmetic disfigurement and/or functional deficits related to the cancer itself or cancer-directed treatments. These physical and emotional symptoms can be demoralizing and require acute and long-term professional assistance throughout a patient's lifespan. HNC remains one of the most challenging cancers to treat due to disfigurement, emotional suffering, social isolation, and loss of self-esteem...
2018: Cancer Treatment and Research
Katherine S McGilton, Riva Sorin-Peters, Elizabeth Rochon, Veronique Boscart, Mary Fox, Charlene H Chu, Steven C Stewart, Souraya Sidani
PURPOSE OF THE STUDY: This small scale study examined the influence of an interprofessional (IP) evidence based patient-centered communication intervention (PCCI), delivered by trained nurses in collaboration with Speech Language Pathologists, on patient outcomes in an active stroke rehabilitation setting. DESIGN AND METHODS: The setting constraints imposed the use of a single-group pretest and post-test design to determine the influence of the intervention on patient outcomes...
February 2018: Applied Nursing Research: ANR
Chelsea Maedler, Thomas Arnason, Alastair Dorreen, Heidi Sapp, Mathieu Castonguay, Joanne Murphy, Sorin Selegean, Weei-Yuarn Huang
Goblet cell carcinoid (GCC) is an uncommon tumor of the vermiform appendix. Due to a broad spectrum of morphological differentiation, subclassification and grading of GCCs remains an area of controversy. Two separate systems have proposed classifying GCC tumors into three (classical GCC; adenocarcinoma ex-GCC, signet ring cell type; adenocarcinoma ex-GCC, poorly differentiated carcinoma type) OR two subgroups (low and high grade GCC) based on morphological criteria. We independently compared the inter-observer variability associated with each classification system...
February 2018: Annals of Diagnostic Pathology
Sorin Aldea, Stéphan Gaillard
Unilateral suprasellar meningiomas have distinct features compared to other midline tumors, as they may produce severe visual symptoms even if small due to an early involvement of the optic canal. Surgical treatment of these tumors from an ipsilateral approach is challenging, as the tumor is covered by the optic nerve that needs to be mobilized to access the optic canal extension. A contralateral approach allows a direct line of sight to the tumor despite a longer working distance. We report the case of a 49-year-old patient presenting with unilateral visual loss related to a left suprasellar meningioma extending to the left optic canal and displacing the optic nerve laterally...
February 2018: Journal of Neurological Surgery. Part B, Skull Base
A Vairinho, A Al Hindi, M Revol, A Legras, K Rem, Y Guenane, S Cristofari, T Sorin
INTRODUCTION: Soft tissue and bone radionecrosis are rare but serious complications may occur late after radiotherapy. CASE REPORT: We report the case of an 86-year-old woman with a history an infiltrating ductal carcinoma of the left breast, treated by total mastectomy, left axillary dissection and adjuvant radiotherapy. Eighteen years later, the first radionecrosis lesions appeared and grew progressively in a 6-month period. These lesions are deep, involving the anterior aspect of the 4th to the 6th ribs and infiltrating the chest wall to the left cardio-thoracic space communicating largely with the pericardium...
February 2, 2018: Annales de Chirurgie Plastique et Esthétique
Deidre McPherson, Valentin Neuhaus, Rohin Dhar, Sorin Edu, Andrew J Nicol, Pradeep H Navsaria
BACKGROUND: The purpose of this study was to determine whether the outcomes of hemodynamically stable patients undergoing exploratory laparotomy for penetrating abdominal trauma differed as a result of their HIV status. METHODS: This was an observational, prospective study from February 2016 to May 2017. All hemodynamically stable patients with penetrating abdominal trauma requiring a laparotomy were included. The mechanism of injury, the HIV status, age, the penetrating abdominal trauma index (PATI), and the revised trauma score (RTS) were entered into a binary logistic regression model...
January 31, 2018: World Journal of Surgery
Henry D Huang, Viren M Patel, Parikshit S Sharma, Zenith Jameria, Sorin Lazar, Richard Trohman, Erik Wissner
No abstract text is available yet for this article.
January 2018: HeartRhythm Case Reports
Kathrin Freystaetter, Faruk Özalp
Quadricuspid aortic valve (QAV) is a rare occurrence, usually presenting with insufficiency rather than stenosis. We report a case of aortic valve replacement in a septuagenarian with a stenotic QAV, achieving a good result with a Sorin Perceval sutureless bioprosthesis. We emphasize the particular technique of implantation and possible pitfalls. Sutureless bioprosthetic valves present a feasible option for aortic valve replacement in patients with uncommon valve morphologies, aiming to reduce operative time...
January 24, 2018: Annals of Thoracic Surgery
Pradeep Navsaria, Andrew Nicol, Jake Krige, Sorin Edu, Sharfuddin Chowdhury
PURPOSE: Nonoperative management (NOM) of gunshot liver injuries (GLI) is infrequently practiced. The aim of this study was to assess the safety of selective NOM of GLI. METHODS: A prospective, protocol-driven study, which included patients with GLI admitted to a level 1 trauma center, was conducted over a 52-month period. Stable patients without peritonism or sustained hypotension with right-sided thoracoabdominal (RTA) and right upper quadrant (RUQ), penetrating wounds with or without localized RUQ tenderness, underwent contrasted abdominal CT scan to determine the trajectory and organ injury...
January 24, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
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