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https://www.readbyqxmd.com/read/28191713/tissue-characterization-and-phenotype-classification-in-patients-presenting-with-acute-myocardial-infarction-insights-from-the-iwonder-study
#1
Cristiano F Souza, Akiko Maehara, Gary S Mintz, Mitsuaki Matsumura, Claudia M R Alves, Antonio Carlos Carvalho, Adriano Caixeta
OBJECTIVES: We sought to assess a new modality of radiofrequency intravascular ultrasound (IVUS) called iMAP-IVUS (Boston Scientific, Santa Clara, California) during the evaluation of patients presenting with high-risk acute coronary syndromes. BACKGROUND: There are limited data on plaque tissue characterization and phenotype classification using iMAP-IVUS. METHODS: In the iWonder study patients presenting with ST-elevation myocardial infarction (STEMI) or non-STEMI underwent three-vessel grayscale IVUS and iMAP-IVUS tissue characterization prior to percutaneous intervention...
February 13, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28153614/internal-maxillary-artery-preoperative-embolization-using-nbca-and-pushable-coils-for-temporomandibular-joint-ankylosis-surgery-technical-note
#2
Yazan J Alderazi, Darshan Shastri, John Wessel, Melvin Mathew, Tareq Kass-Hout, Shahid R Aziz, Charles J Prestigiacomo, Chirag D Gandhi
INTRODUCTION: Temporomandibular joint (TMJ) ankylosis causes disability through impaired digestion, mastication, speech and appearance. Surgical treatment increases range of motion with resultant functional improvement. However, substantial perioperative blood loss can occur, up to three liters, if the internal maxillary artery (IMAX) is injured as it traverses the ankylotic mass. Achieving hemostasis is difficult due to limited proximal IMAX access and poor visualization. Our aim is to investigate the technical feasibility and preliminary safety of preoperative IMAX embolization in patients undergoing TMJ ankylosis surgery...
January 30, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28149625/five-years-of-keeping-a-watch-on-the-left-atrial-appendage-how-has-the-watchman-fared
#3
COMMENT
Mohammad-Ali Jazayeri, Venkat Vuddanda, Valay Parikh, Madhav Lavu, Donita Atkins, Y Madhu Reddy, Jayant Nath, Dhanunjaya R Lakkireddy
Left atrial appendage closure (LAAC) is a promising site-directed therapy for stroke prevention in patients with non-valvular atrial fibrillation (AF) who are ineligible or contraindicated for long-term oral anticoagulation. A variety of LAAC modalities are available, including percutaneous endocardial occluder devices such as WATCHMAN(TM) (Boston Scientific Corp., Marlborough, MA, USA), and an ever-increasing body of evidence is helping to define the optimal use of each technique. Similarly increased experience with LAAC has revealed challenges such as device-related thrombi and peri-device leaks for which the long-term significance and appropriate management are areas of active investigation...
December 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28104422/tipless-nitinol-stone-baskets-comparison-of-penetration-force-radial-dilation-force-opening-dynamics-and-deflection
#4
Nishant Patel, Arash Akhavein, Bryan Hinck, Rajat Jain, Manoj Monga
OBJECTIVE: To evaluate 5 commercially available tipless nitinol baskets (2.2F) in 4performance factors: penetration force, radial dilation force, opening dynamics and deflection limitation. MATERIAL AND METHODS: The 2.2F Coloplast Dormia No-Tip®, 1.5F Sacred Heart Medical Halo®, 2.2F Cook NCircle Nitinol Tipless Stone Extractor ®, 1.9F Bard SkyLite Tipless Nitinol Basket® and the 1.9F Boston Scientific Zero TipTM baskets were tested for penetration force (safety metric), radial dilation force (functional metric for ureteral calculi), and opening/closing dynamics...
January 16, 2017: Urology
https://www.readbyqxmd.com/read/28097472/proceedings-of-the-third-international-molecular-pathological-epidemiology-mpe-meeting
#5
REVIEW
Peter T Campbell, Timothy R Rebbeck, Reiko Nishihara, Andrew H Beck, Colin B Begg, Alexei A Bogdanov, Yin Cao, Helen G Coleman, Gordon J Freeman, Yujing J Heng, Curtis Huttenhower, Rafael A Irizarry, N Sertac Kip, Franziska Michor, Daniel Nevo, Ulrike Peters, Amanda I Phipps, Elizabeth M Poole, Zhi Rong Qian, John Quackenbush, Harlan Robins, Peter K Rogan, Martha L Slattery, Stephanie A Smith-Warner, Mingyang Song, Tyler J VanderWeele, Daniel Xia, Emily C Zabor, Xuehong Zhang, Molin Wang, Shuji Ogino
Molecular pathological epidemiology (MPE) is a transdisciplinary and relatively new scientific discipline that integrates theory, methods, and resources from epidemiology, pathology, biostatistics, bioinformatics, and computational biology. The underlying objective of MPE research is to better understand the etiology and progression of complex and heterogeneous human diseases with the goal of informing prevention and treatment efforts in population health and clinical medicine. Although MPE research has been commonly applied to investigating breast, lung, and colorectal cancers, its methodology can be used to study most diseases...
February 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28086805/the-safety-of-introducing-a-new-generation-tavr-device-one-departments-experience-from-introducing-a-second-generation-repositionable-tavr
#6
Henrik Bjursten, Shahab Nozohoor, Malin Johansson, Igor Zindovic, Carl-Fredrik Appel, Johan Sjögren, Magnus Dencker, Göran Olivecrona, Jan Harnek, Sasha Koul, Ted Feldman, Michael J Reardon, Matthias Götberg
BACKGROUND: In the evolving field of transcatheter aortic valve replacements a new generation of valves have been introduced to clinical practice. With the complexity of the TAVR procedure and the unique aspects of each TAVR device, there is a perceived risk that changing or adding a new valve in a department could lead to a worse outcome for patients, especially during the learning phase. The objective was to study the safety aspect of introducing a second generation repositionable transcatheter valve (Boston Scientific Lotus valve besides Edwards Sapien valve) in a department...
January 13, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28073884/pacemaker-detected-severe-sleep-apnea-predicts-new-onset-atrial-fibrillation
#7
Andrea Mazza, Maria Grazia Bendini, Raffaele De Cristofaro, Mariolina Lovecchio, Sergio Valsecchi, Giuseppe Boriani
AIMS: Sleep apnea (SA) diagnosed on overnight polysomnography is a risk factor for atrial fibrillation (AF). Advanced pacemakers are now able to monitor intrathoracic impedance for automatic detection of SA events. METHODS AND RESULTS: We enrolled 160 consecutive recipients of a dual-chamber pacemaker endowed with the ApneaScan algorithm (Boston Scientific). If the pacemaker-measured Respiratory Disturbance Index was ≥30 episodes per hour for at least one night during the first week after implantation, SA was defined as severe...
January 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28070890/the-role-of-conventional-and-right-sided-ecg-screening-for-subcutaneous-icd-in-a-tetralogy-of-fallot-population
#8
Pau Alonso, Joaquín Osca, Oscar Cano, Pedro Pimenta, Ana Andrés, Jaime Yagüe, José Millet, Joaquín Rueda, María José Sancho-Tello
BACKGROUND: Information regarding suitability for S-ICD implant in Tetralogy of Fallot (ToF) population is scarce and needs to be further explored. THE AIMS OF OUR STUDY WERE: (i) to determine the proportion of patients with ToF eligible for S-ICD, (ii) to identify the optimal sensing vector in ToF patients, (iii) to test specifically the eligibility for sICD with right-sided screening, and (iv) to compare with the proportion of eligible patients in a non-selected ICD population...
January 10, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28057045/validation-of-a-new-method-for-the-endoscopic-measurement-of-post-bariatric-gastric-outlet-using-a-standard-guidewire-an-observer-agreement-study
#9
Luiz Gustavo de Quadros, Manoel Dos Passos Galvão Neto, Josemberg Marins Campos, Roberto Luiz Kaiser Junior, Eduardo Grecco, Mario Flamini Junior, Marcelo Falcao de Santana, Idiberto Jose Zotarelli Filho, Adriano Augusto Tomas Vasconcelos Almeida Alexandre
BACKGROUND AND AIMS: Between 10 and 20% of all patients undergoing bariatric surgery procedures regain weight secondary to a gastrojejunostomy enlargement. The aim of this study was to validate the interobserver agreement while measuring gastric outlet diameters using a new standard guidewire. METHODS: We selected thirty-five videos of consecutive endoscopic procedures on patients undergoing esophagogastroduodenoscopy after a Roux-en-Y gastric bypass procedure. All videos were evaluated by four raters: two expert endoscopists and two trainees...
January 3, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28031677/durable-results-with-in-situ-graft-repair-of-ruptured-salmonella-aneurysm-in-a-patient-with-autoimmune-deficiency-syndrome
#10
Patrick C Thompson, Lisa Wang, Jesse Columbo, Andres Schanzer, William P Robinson
We describe a case of a 42-year-old male patient with advanced autoimmune deficiency syndrome (AIDS) (CD4 count of 16 cells/mm(3)) found to have a ruptured infected infrarenal aortic aneurysm. Emergent in situ repair was performed with a Hemashield Dacron graft (Boston Scientific, Natick, MA). Aortic tissue cultures grew group D Salmonella. Patient was placed initially on intravenous ciprofloxacin followed by lifelong oral levofloxacin and trimethoprim. Over 2 years following repair, he remains asymptomatic, with repair intact and no recurrent infection...
December 2016: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/27989696/methyl-mercury-exposure-and-neurodevelopmental-outcomes-in-the-seychelles-child-development-study-main-cohort-at-age-22-and-24years
#11
Edwin van Wijngaarden, Sally W Thurston, Gary J Myers, Donald Harrington, Deborah A Cory-Slechta, J J Strain, Gene E Watson, Grazyna Zareba, Tanzy Love, Juliette Henderson, Conrad F Shamlaye, Philip W Davidson
BACKGROUND: All fish contain methyl mercury (MeHg), a known neurotoxicant at adequate dosage. There is still substantial scientific uncertainty about the consequences, if any, of mothers consuming fish with naturally-acquired levels of MeHg contamination. In 1989-1990, we recruited the Main Cohort of the Seychelles Child Development Study to assess the potential developmental effects of prenatal MeHg exposure. We report here on associations with neurodevelopmental outcomes obtained at 22 and 24years of age...
January 2017: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/27987616/deep-venous-thrombosis-associated-with-caval-extension-of-iliac-stents
#12
Erin H Murphy, Blake Johns, Elliot Varney, William Buck, Arjun Jayaraj, Seshadri Raju
BACKGROUND: It is generally difficult to place an iliac vein stent precisely at the iliocaval junction with venographic control or even with intravascular ultrasound guidance. Furthermore, mechanical properties of the Wallstent (Boston Scientific, Marlborough, Mass) can predispose precisely placed stents to distal displacement or stent collapse. Our center has thus advocated extending Wallstents 3 to 5 cm into the inferior vena cava to prevent complications of missed proximal lesions or stent migration...
January 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27981862/evaluation-of-a-novel-single-use-flexible-ureteroscope
#13
Joanne Andrea Dale, Adam Geoffrey Kaplan, Daniela Radvak, Richard Shin, Anika Ackerman, Tony T Chen, Charles D Scales, Michael N Ferrandino, W Neal Simmons, Glenn M Preminger, Michael Eric Lipkin
INTRODUCTION: A novel single-use flexible ureteroscope promises the optical characteristics and maneuverability of a reusable 4th generation flexible ureteroscope. In this study, the LithoVue Single-Use Digital flexible ureteroscope was directly compared to contemporary reusable flexible ureteroscopes, with regards to optics, deflection and irrigation flow. METHODS: Three flexible ureteroscopes including the LithoVue (Single Use, Boston Scientific, USA), Flex-Xc (Karl Storz, Germany) and Cobra (Richard Wolf, Germany) were assessed in vitro for image resolution, distortion, color representation, grayscale imaging, field of view and depth of field...
December 16, 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27974669/initial-experience-of-bioabsorbable-polymer-everolimus-eluting-synergy-stents-in-high-risk-patients-undergoing-complex-percutaneous-coronary-intervention-with-early-discontinuation-of-dual-antiplatelet-therapy
#14
Rebecca L Noad, Colm G Hanratty, Simon J Walsh
AIMS: As more elderly and co-morbid patients require percutaneous revascularization, 1 year of dual-antiplatelet therapy (DAPT) becomes concerning. Synergy stents (Boston Scientific) allow for early cessation of DAPT. This study assessed those in our unit who underwent percutaneous coronary intervention (PCI) with a Synergy stent to examine a minimum of 6 months of clinical outcomes after early discontinuation of DAPT. METHODS AND RESULTS: All non-trial patients in our unit who had PCI with a Synergy stent from August 2013 to February 2016 were retrospectively analyzed...
February 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27974668/importance-of-adjunct-delivery-techniques-to-optimize-deployment-success-of-distal-protection-filters-during-vein-graft-intervention
#15
Antony G Kaliyadan, Harnish Chawla, David L Fischman, Nicholas Ruggiero, Michael Gannon, Paul Walinsky, Michael P Savage
OBJECTIVES: This study assessed the impact of adjunct delivery techniques on the deployment success of distal protection filters in saphenous vein grafts (SVGs). BACKGROUND: Despite their proven clinical benefit, distal protection devices are underutilized in SVG interventions. Deployment of distal protection filters can be technically challenging in the presence of complex anatomy. Techniques that facilitate the delivery success of these devices could potentially improve clinical outcomes and promote greater use of distal protection...
February 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27970129/tct-744-new-generation-devices-for-transfemoral-transcatheter-aortic-valve-replacement-boston-scientific-lotus-valve-and-edwards-sapien-3-are-superior-compared-with-last-generation-devices-edwards-xt-and-medtronic-corevalve-with-respect-to-varc-2-outcome
#16
Julia Seeger, Birgid Gonska, Christoph Rodewald, Wolfgang Rottbauer, Jochen Wöhrle
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970036/tct-663-twelve-months-outcome-in-patients-undergoing-transfemoral-aortic-valve-replacement-tavr-with-the-repositionable-and-retrievable-boston-scientific-lotus-valve-compared-with-the-balloon-expandable-edwards-sapien-3-device
#17
Julia Seeger, Birgid Gonska, Christoph Rodewald, Wolfgang Rottbauer, Jochen Wöhrle
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27920835/atriofascicular-pathway-detection-with-novel-ablation-catheter
#18
Padmanabhan Shakkottai, Adrian Baranchuk, Neil Hobson, Jane Caldwell
Atriofascicular pathways are a rare cause of antidromic atrioventricular reciprocating tachycardia. The IntellaTip MiFi ablation catheter (Boston Scientific, MA, USA) is a novel ablation catheter that allows enhanced signal clarity with highly localized electrograms. This is the first report of this catheter being successfully used to map and ablate the atriofascicular pathway potentials.
December 2016: Journal of Arrhythmia
https://www.readbyqxmd.com/read/27913272/the-northeast-regional-sps-meeting-update-safety-pharmacology-innovations-and-applications
#19
REVIEW
Malar Pannirselvam, Tiffini Brabham, Alfred W Botchway, Donald B Hodges, Martin Traebert, Michael K Pugsley
The Safety Pharmacology Society (SPS) held a Northeast (NE) regional meeting in Boston, MA on May 13, 2016 at the Vertex Pharmaceuticals Incorporated site. There were 103 attendees from the pharmaceutical industry, contract research organizations (CROs), academia, and global regulatory agencies. An assortment of scientific topics were presented by 7 speakers that included broad topics in the cardiovascular (organ on chip, statistical power and translation of rat cardiovascular telemetry data and dual inhibition of IKr and IKs on QT interval prolongation) and central nervous system (in vitro platform for neurotoxicity, an integrated risk assessment of suicidal ideation and behavior, and EEG advances in safety pharmacology) and a novel topic discussing preclinical challenges faced in the development of a novel gene therapy...
November 29, 2016: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/27894948/don-t-be-rejected-how-can-we-help-authors-reviewers-and-editors-report-of-a-symposium-for-editors-publishers-and-others-with-an-interest-in-scientific-publication-held-in-boston-on-wednesday-11-march-2015-during-the-annual-meeting-of-the-international-association
#20
K A Eaton, N Innes, S M Balaji, C Pugh, E Honkala, C D Lynch
This satellite symposium was the fifth in a series for editors, publishers, reviewers and all those with an interest in scientific publishing. It was held on Wednesday, 11 March 2015 at the IADR meeting in Boston, Massachusetts. The symposium attracted more than 210 attendees. The symposium placed an emphasis on strategies to ensure that papers are accepted by peer reviewed journals. The speaker, representing the Journal of Dental Research gave a history of peer review and explained how to access material to advise new authors...
November 25, 2016: Journal of Dentistry
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