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Monika Mohanbhai Agrawal, Rashmi Samir Mahajan, Freny Erachshaw Bilimoria, Kishan Rasubhai Ninama
No abstract text is available yet for this article.
November 2016: Indian Journal of Dermatology
K Jayaprakash Shetty, Chandrika Rao, H L Kishan Prasad
No abstract text is available yet for this article.
December 2016: Indian Journal of Surgical Oncology
Jonathan Nylk, Kaley McCluskey, Sanya Aggarwal, Javier A Tello, Kishan Dholakia
We have investigated the effect of Airy illumination on the image quality and depth penetration of digitally scanned light-sheet microscopy in turbid neural tissue. We used Fourier analysis of images acquired using Gaussian and Airy light-sheets to assess their respective image quality versus penetration into the tissue. We observed a three-fold average improvement in image quality at 50 μm depth with the Airy light-sheet. We also used optical clearing to tune the scattering properties of the tissue and found that the improvement when using an Airy light-sheet is greater in the presence of stronger sample-induced aberrations...
October 1, 2016: Biomedical Optics Express
Samarjit S Ghuman, Saumya Gupta, T B S Buxi, Kishan S Rawat, Anurag Yadav, Naimish Mehta, Seema Sud
Abernethy malformation, also known as congenital extrahepatic portosystemic shunts (CEPS) is a rare clinical entity and manifests with different clinical symptoms. CEPS are abnormalities of vascular development where there is shunting of portal blood into the systemic venous system. Multidetector computed tomography (MDCT) is a fast and effective modality for evaluation of CEPS. CT displays all the information desired by the surgeon as well as the clinician including the anatomy of the splenic and superior mesenteric veins, size and site of the shunt, presence or absence of the portal vein radicles, and helps to plan the therapy and even the follow-up of these patients...
July 2016: Indian Journal of Radiology & Imaging
Naomi McReynolds, Juan M Auñón Garcia, Zoe Guengerich, Terry K Smith, Kishan Dholakia
We demonstrate the ability to discriminate between five brands of commercially available extra-virgin olive oil (EVOO) using Raman spectroscopy or fluorescence spectroscopy. Data was taken on both a 'bulk optics' free space system and on a compact handheld device, each capable of taking both Raman and fluorescence data. With the compact Raman device we achieved an average sensitivity and specificity of 98.4% and 99.6% for discrimination, respectively. Our approach illustrates that both Raman and fluorescence spectroscopy can be used for portable discrimination of EVOOs...
November 2016: Applied Spectroscopy
Razia Sultana Janampet, Kishan Kumar Malavath, Rajanna Neeradi, Satyanarayana Chedurupalli, Raghunandan Thirunahari
AIM: This study was conducted to evaluate the growth performance and nutrient digestibility of guar meal, an unconventional protein-rich feed ingredient in kids in comparison to conventional groundnut cake. MATERIALS AND METHODS: A total of 18 kids were randomly allotted to three groups, and T1 group was fed on basal diet, T2 and T3 groups were offered diet replacing groundnut cake at 50% and 100% with guar meal, respectively, for a period of 120-day. At the end of the growth trial, a digestibility trial was conducted to evaluate the nutrient utilization...
October 2016: Veterinary World
Narendar Dudhipala, Kishan Veerabrahma
The intent of this investigation was to improve pharmacokinetic (PK) and pharmacodynamic (PD) effects of Rosuvastatin calcium (RC) by solid lipid nanoparticles (SLNs). RC is anti-hyperlipidemic drug with low oral bioavailability (20%) due to first-pass metabolism. Hot homogenization followed by ultrasonication method was used to prepare RC-SLNs with stearic acid, glyceryl behenate and glyceryl trilaurate as lipid matrices, egg lecithin and poloxamer 188 as surfactants. The prepared SLNs were tested for particle size, PDI, zeta potential (ZP), entrapment efficiency (EE), drug content and in vitro release...
October 31, 2016: European Journal of Pharmaceutics and Biopharmaceutics
Kishan A Manani, Kim Christensen, Nicholas S Peters
Atrial fibrillation (AF) increases the risk of stroke by a factor of 4-5 and is the most common abnormal heart rhythm. The progression of AF with age, from short self-terminating episodes to persistence, varies between individuals and is poorly understood. An inability to understand and predict variation in AF progression has resulted in less patient-specific therapy. Likewise, it has been a challenge to relate the microstructural features of heart muscle tissue (myocardial architecture) with the emergent temporal clinical patterns of AF...
October 2016: Physical Review. E
Amar U Kishan, Percy Lee
Non-small cell lung cancer (NSCLC) is the second most common solid malignancy in the United States of America, and the leading cause of cancer-related mortality. Nearly 15% of patients present with early-stage disease, for which the standard of care is lobectomy. However, the median age at diagnosis ranges from 65 to 74 years, and many patients have significant comorbidities that preclude surgical treatment. Previously, the standard of care for these patients was definitive radiotherapy (RT) with conventional fractionation (i...
October 2016: Seminars in Respiratory and Critical Care Medicine
Esther Rani P, N Kishan
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
Timothy E Audas, Danielle E Audas, Mathieu D Jacob, J J David Ho, Mireille Khacho, Miling Wang, J Kishan Perera, Caroline Gardiner, Clay A Bennett, Trajen Head, Oleksandr N Kryvenko, Mercé Jorda, Sylvia Daunert, Arun Malhotra, Laura Trinkle-Mulcahy, Mark L Gonzalgo, Stephen Lee
The amyloid state of protein organization is typically associated with debilitating human neuropathies and is seldom observed in physiology. Here, we uncover a systemic program that leverages the amyloidogenic propensity of proteins to regulate cell adaptation to stressors. On stimulus, cells assemble the amyloid bodies (A-bodies), nuclear foci containing heterogeneous proteins with amyloid-like biophysical properties. A discrete peptidic sequence, termed the amyloid-converting motif (ACM), is capable of targeting proteins to the A-bodies by interacting with ribosomal intergenic noncoding RNA (rIGSRNA)...
October 24, 2016: Developmental Cell
Kishan Bakrania, Thomas Yates, Alex V Rowlands, Dale W Esliger, Sarah Bunnewell, James Sanders, Melanie Davies, Kamlesh Khunti, Charlotte L Edwardson
OBJECTIVES: (1) To develop and internally-validate Euclidean Norm Minus One (ENMO) and Mean Amplitude Deviation (MAD) thresholds for separating sedentary behaviours from common light-intensity physical activities using raw acceleration data collected from both hip- and wrist-worn tri-axial accelerometers; and (2) to compare and evaluate the performances between the ENMO and MAD metrics. METHODS: Thirty-three adults [mean age (standard deviation (SD)) = 27.4 (5.9) years; mean BMI (SD) = 23...
2016: PloS One
Vernon Bond, Bryan H Curry, Krishna Kumar, Sudhakar Pemminati, Vasavi R Gorantla, Kishan Kadur, Richard M Millis
OBJECTIVES: Acupuncture treatments are safe and effective for a wide variety of diseases involving autonomic dysregulation. Heart rate variability (HRV) is a noninvasive method for assessing sympathovagal balance. The low frequency/high frequency (LF/HF) spectral power ratio is an index of sympathovagal influence on heart rate and of cardiovascular health. This study tests the hypothesis that from rest to 30% to 50% of peak oxygen consumption, the nonlinear Conte-Zbilut-Federici (CZF) method of computing the LF/HF ratio is a more reliable index of changes in the HRV than linear methods are...
September 2016: Journal of Pharmacopuncture
Kishan S Parikh, Melissa A Greiner, Takeki Suzuki, Adam D DeVore, Chad Blackshear, Joseph F Maher, Lesley H Curtis, Adrian F Hernandez, Emily C O'Brien, Robert J Mentz
Importance: Increased resting heart rate is associated with worse outcomes in studies of mostly white populations, but its significance is not well established in African Americans persons whose cardiac comorbidities and structural abnormalities differ. Objective: To study the prognostic utility of heart rate in a community-based African American cohort in the Jackson Heart Study. Design, Setting, and Participants: A total of 5261 participants in the Jackson Heart Study, a prospective, community-based study in Jackson, Mississippi, were evaluated...
September 28, 2016: JAMA Cardiology
D O'Connell, N Shaverdian, A U Kishan, D H Thomas, L Yang, J Lewis, J M Lamb, M Cao, S E Tenn, P Lee, D Low
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
J D D Pennington, A U Kishan, A M Chen
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
N Shaverdian, J Demanes, D Veruttipong, J Wang, A U Kishan, S A McCloskey, P A Kupelian, M L Steinberg, C R King
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
A U Kishan, T Shaikh, J Wang, R Reiter, J Said, G Raghavan, N Nickols, W Aronson, A Sadeghi, M Kamrava, D J Demanes, M L Steinberg, E M Horwitz, P A Kupelian, C R King
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
A U Kishan, J Wang, J C Rwigema, C Saigal, M Rettig, M L Steinberg, C R King
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Anudeep Sandanamudi, Kishan R Bharadwaj, Radha Cheruppanpullil
Chitin binding activity of moringa seed resistant protein (MSRP) isolated from defatted moringa seed flour was investigated in the present study "Characterization of soluble dietary fiber from Moringa oleifera seeds and its immunomodulatory effects" (S. Anudeep, V.K. Prasanna, S.M. Adya, C. Radha, 2016) [1]. The assay reaction mixture contained 0.4 mg/ml of MSRP and different amounts (20-100 mg) of chitin. MSRP exhibited binding activity over wide range of chitin concentration. Maximum binding activity was observed at 80 mg of chitin...
December 2016: Data in Brief
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