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https://www.readbyqxmd.com/read/29691948/lifestyle-factors-and-the-course-of-depression-in-older-adults-a-nesdo-study
#1
REVIEW
Myrthe C Bruin, Hannie C Comijs, Rob M Kok, Roos C Van der Mast, Julia F Van den Berg
OBJECTIVES: To investigate whether lifestyle indicators including physical exercise, sleep duration, alcohol use, body mass index, smoking status, and a composite lifestyle index are associated with the depression course in older adults. METHODS: Data of 283 older adults were used from the Netherlands Study of Depression in Older Persons. Depressive disorders at baseline were assessed with the Composite International Diagnostic Interview. The depression course at 2-year follow-up was assessed with the Inventory of Depressive Symptoms (IDS, score 0-84) every 6 months; physical exercise with the International Physical Activity Questionnaire; alcohol use with the Alcohol Use Disorders Identification Test; body mass index by anthropometry; and sleep duration and smoking status by interview questions...
April 24, 2018: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29691788/tissue-identification-in-a-porcine-model-by-differential-ion-mobility-spectrometry-analysis-of-surgical-smoke
#2
Anton Kontunen, Markus Karjalainen, Jukka Lekkala, Antti Roine, Niku Oksala
Electrosurgery is widely used in various surgical operations. When tissue is cut with high-frequency current, the cell contents at the incision area evaporate and together with water and possible soot particles, form surgical smoke. The smoke contains cell metabolites, and therefore, possible biomarkers for cancer or bacterial infection. Thus, the analysis of surgical smoke could be used in intraoperative medical diagnostics. We present a method that can be used to detect the characteristics of various tissue types by means of differential ion mobility spectrometry (DMS) analysis of surgical smoke...
April 24, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29691685/adherence-and-health-literacy-as-related-to-outcome-of-patients-treated-for-rheumatoid-arthritis-analyses-of-a-large-scale-observational-study
#3
J G Kuipers, M Koller, F Zeman, K Müller, J U Rüffer
BACKGROUND: Disabilities in daily living and quality of life are key endpoints for evaluating the treatment outcome for rheumatoid arthritis (RA). Factors possibly contributing to good outcome are adherence and health literacy. METHODS: The survey included a representative nationwide sample of German rheumatologists and their patients with RA. The physician questionnaire included the disease activity score (DAS28) and medical prescriptions. The patient questionnaire included fatigue (EORTC QLQ-FA13), health assessment questionnaire (HAQ), quality of life (SF-12), health literacy (HELP), and patients' listings of their medications...
April 24, 2018: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/29691286/cognitive-function-trajectories-and-their-determinants-in-older-people-8-years-of-follow-up-in-the-english-longitudinal-study-of-ageing
#4
Paola Zaninotto, G David Batty, Michael Allerhand, Ian J Deary
BACKGROUND: Maintaining cognitive function is an important aspect of healthy ageing. In this study, we examined age trajectories of cognitive decline in a large nationally representative sample of older people in England. We explored the factors that influence such decline and whether these differed by gender. METHODS: Latent growth curve modelling was used to explore age-specific changes, and influences on them, in an 8-year period in memory, executive function, processing speed and global cognitive function among 10 626 participants in the English Longitudinal Study of Ageing...
April 24, 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29691216/the-usability-and-effectiveness-of-mobile-health-technology-based-lifestyle-and-medical-intervention-apps-supporting-health-care-during-pregnancy-systematic-review
#5
REVIEW
Sanne B Overdijkink, Adeline V Velu, Ageeth N Rosman, Monique Dm van Beukering, Marjolein Kok, Regine Pm Steegers-Theunissen
BACKGROUND: A growing number of mobile health (mHealth) technology-based apps are being developed for personal lifestyle and medical health care support, of which several apps are related to pregnancy. Evidence on usability and effectiveness is limited but crucial for successful implementation. OBJECTIVE: This study aimed to evaluate the usability, that is, feasibility and acceptability, as well as effectiveness of mHealth lifestyle and medical apps to support health care during pregnancy in high-income countries...
April 24, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29691142/oxidative-stress-biomarkers-and-clinical-dimensions-in-first-10-years-of-schizophrenia
#6
Leticia González-Blanco, María Paz García-Portilla, Leticia García-Álvarez, Lorena de la Fuente-Tomás, Celso Iglesias García, Pilar A Sáiz, Susana Rodríguez-González, Ana Coto-Montes, Julio Bobes
INTRODUCTION: Several studies have described increased oxidative stress parameters in patients with schizophrenia. The objectives of the current study were to identify potential oxidative stress biomarkers in stable patients during first 10 years of schizophrenia and determine if they are associated with specific clinical dimensions. MATERIAL AND METHODS: Seventy-three clinically stable outpatients with schizophrenia and 73 sex and age-matched healthy controls were recruited...
April 21, 2018: Revista de Psiquiatrí́a y Salud Mental
https://www.readbyqxmd.com/read/29691085/the-smyd3-vntr-3-3-polymorphism-confers-an-increased-risk-and-poor-prognosis-of-hepatocellular-carcinoma-in-a-chinese-population
#7
Rui-Dong Li, Yan-Hua Tang, Hui-Li Wang, Dong Yang, Li-Jun Sun, Wei Li
OBJECTIVE: Hepatocellular carcinoma (HCC) is one of the most lethal human malignancies in China, and the genetic link of hepatocarcinogenesis remains to be defined. Thus, we explored the role of SET and myeloid translocation protein 8, Nervy, and DEAF1 (MYND) domain containing protein 3 (SMYD3) gene polymorphism on risk and prognosis of HCC. METHODS: A total of 236 patients with HCC who received treatment in Affiliated Hospital of Jining Medical University for the first time and 230 healthy individuals were enrolled in the study...
April 17, 2018: Pathology, Research and Practice
https://www.readbyqxmd.com/read/29690773/therapeutic-inertia-in-antiplatelet-therapy-in-patients-with-a-cardiovascular-event-attended-in-an-emergency-department
#8
José Antonio García-Macías, Antonio Palazón-Bru, María Ángeles Carbonell-Torregrosa, Miguel Navarro-Juan, Vicente Francisco Gil-Guillén
OBJECTIVE: As very few studies have assessed therapeutic inertia (TI) in antiplatelet therapy in patients in secondary cardiovascular prevention, we designed a study in our hospital emergency department to quantify its magnitude and its associated factors. METHODS: This descriptive cross-sectional observational study involved a sample of 223 patients with a history of cardiovascular disease and recommendation for antiplatelet therapy who attended the emergency department in a Spanish region in 2016...
April 25, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29690696/-expression-and-potential-clinical-significance-of-cytidine-triphosphate-phosphocholine-cytidylyltransferase-%C3%AE-in-oral-squamous-cell-carcinoma
#9
F C Lu, X Y Xie, X M Yin, Y J Gao
Objective: To examine the expression and potential clinical significance of CCT (cytidine triphosphate: phosphocholine cytidylyltransferase)-α in oral squamous cell carcinoma (OSCC). Methods: Fifty-eight OSCC and paired adjacent non-malignant epithelia samples (between May 2016 and July 2016) were obtained from dental center, Second Xiangya Hospital, Central South University. CCT-α expression was examined by immunohistochemistry. The relationship between CCT-α and clinicopathological features of OSCC patients was analyzed...
April 9, 2018: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/29690578/depressive-symptoms-increase-the-risk-of-mortality-for-white-but-not-black-older-adults
#10
Shervin Assari
Introduction. Long-term studies have shown that depressive symptoms predict the risk of mortality. However, it is unknown if this effect is present in shorter time intervals. In addition, recent research suggests that the salience of the negative affect on the risk of mortality is not similar across racial groups. The current study uses data from a national study of Black and White older adults to examine racial differences in the effect of baseline depressive symptoms on mortality risk over three years in the United States...
April 23, 2018: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29690521/the-gaba-a-receptor-%C3%AE-2-subunit-activates-a-neuronal-tlr4-signal-in-the-ventral-tegmental-area-that-regulates-alcohol-and-nicotine-abuse
#11
Irina Balan, Kaitlin T Warnock, Adam Puche, Marjorie C Gondre-Lewis, Harry June, Laure Aurelian
Alcoholism initiates with episodes of excessive alcohol drinking, known as binge drinking, which is one form of excessive drinking (NIAAA Newsletter, 2004) that is related to impulsivity and anxiety (Ducci et al., 2007; Edenberg et al., 2004) and is also predictive of smoking status. The predisposition of non-alcohol exposed subjects to initiate binge drinking is controlled by neuroimmune signaling that includes an innately activated neuronal Toll-like receptor 4 (TLR4) signal. This signal also regulates cognitive impulsivity, a heritable trait that defines drug abuse initiation...
April 21, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29690510/reference-intervals-for-urinary-cotinine-levels-and-the-influence-of-sampling-time-and-other-predictors-on-its-excretion-among-italian-schoolchildren
#12
Carmela Protano, Roberta Andreoli, Antonio Mutti, Maurizio Manigrasso, Pasquale Avino, Matteo Vitali
(1) Background: Environmental Tobacco Smoke (ETS) exposure remains a public health problem worldwide. The aims are to establish urinary (u-) cotinine reference values for healthy Italian children, to evaluate the role of the sampling time and of other factors on children's u-cotinine excretion. (2) Methods: A cross-sectional study was performed on 330 children. Information on participants was gathered by a questionnaire and u-cotinine was determined in two samples for each child, collected during the evening and the next morning...
April 21, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29689496/methylallyl-sulfone-attenuates-inflammation-oxidative-stress-and-lung-injury-induced-by-cigarette-smoke-extract-in-mice-and-raw264-7-cells
#13
Ang Li, Yan Liu, Xiaosong Zhu, Xiao Sun, Xiuli Feng, Dawei Li, Jiangqiang Zhang, Meihua Zhu, Zhongxi Zhao
In this study, we revealed that methylallyl sulfone (AMSO2), the metabolite of active organosulfur compounds, had anti-inflammatory and antioxidant effect in a cigarette smoke extract (CSE)-induced lung injury model. Firstly, histological analysis showed that the CSE group exhibited lung injury compared with the control, which was alleviated by AMSO2. Secondly, we estimated its anti-inflammatory capacity. The results indicated that pretreatment with AMSO2 significantly decreased CSE-elevated tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in serum...
April 21, 2018: International Immunopharmacology
https://www.readbyqxmd.com/read/29689485/the-effect-of-high-dose-dronabinol-oral-thc-maintenance-on-cannabis-self-administration
#14
Nicolas J Schlienz, Dustin C Lee, Maxine L Stitzer, Ryan Vandrey
BACKGROUND: There is a clear need for advancing the treatment of cannabis use disorders. Prior research has demonstrated that dronabinol (oral THC) can dose-dependently suppress cannabis withdrawal and reduce the acute effects of smoked cannabis. The present study was conducted to evaluate whether high-dose dronabinol could reduce cannabis self-administration among daily users. METHODS: Non-treatment seeking daily cannabis users (N = 13) completed a residential within-subjects crossover study and were administered placebo, low-dose dronabinol (120 mg/day; 40 mg tid), or high-dose dronabinol (180-240 mg/day; 60-80 mg tid) for 12 consecutive days (order counterbalanced)...
April 17, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29689471/prevalence-and-characteristics-of-young-adult-smokers-in-the-u-s-in-the-precontemplation-stage-of-smoking-cessation
#15
Mary E Andrews, Melanie Sabado, Kelvin Choi
INTRODUCTION: The precontemplation stage of smoking cessation refers to having no intention to quit smoking in the next six months. We aimed to estimate the prevalence of and characteristics associated with the precontemplation stage of smoking cessation among U.S. young adult smokers to inform the development of targeted interventions. METHODS: We analyzed data in 2017 from the 2013-2014 National Adult Tobacco Survey. Young adult (18-29 years old) daily and non-daily smokers were included (n = 1809)...
April 9, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29689434/estimating-the-cost-effectiveness-of-lung-cancer-screening-with-low-dose-computed-tomography-for-high-risk-smokers-in-australia
#16
Stephen Wade, Marianne Weber, Michael Caruana, Yoon-Jung Kang, Henry Marshall, Renee Manser, Shalini Vinod, Nicole Rankin, Kwun Fong, Karen Canfell
BACKGROUND: Health economic evaluations of lung cancer screening with low dose computerised tomography (LDCT) that are underpinned by clinical outcomes are few. METHODS: We assessed the cost-effectiveness of LDCT lung screening in Australia by applying Australian cost and survival data to the outcomes observed in the U.S. National Lung Screening Trial (NLST), in which a 20% lung cancer mortality benefit was demonstrated for three rounds of annual screening among high-risk smokers aged 55-74 years...
April 21, 2018: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/29689290/multigenerational-effects-of-maternal-cigarette-smoke-exposure-during-pregnancy-on-sperm-counts-of-f1-and-f2-male-offspring
#17
Hye Jeong Lee, Na Young Choi, Yo Seph Park, Seung-Won Lee, Jin Seok Bang, Yukyeong Lee, Jae-Sung Ryu, Seong-Jin Choi, Sang-Hyub Lee, Gwang Soo Kim, Hyun Woo Chung, Kisung Ko, Kyuhong Lee, Kinarm Ko
Animal models and human studies showed that in utero cigarette smoke exposure decreases sperm counts of offspring. This study used a mouse model to investigate the effects of maternal exposure to cigarette smoke on reproductive systems in F1 and F2 male offspring. Female ICR mice were exposed either to clean air or to cigarette smoke during pregnancy at the post-implantation stage. Epididymal sperm counts were decreased in a cigarette smoke dose-dependent manner in F1 (by 40-60%) and F2 males (by 23-40%) at postnatal day 56...
April 21, 2018: Reproductive Toxicology
https://www.readbyqxmd.com/read/29688777/frequency-of-cannabis-use-and-medical-cannabis-use-among-persons-living-with-hiv-in-the-united-states-findings-from-a-nationally-representative-sample
#18
Lauren R Pacek, Sheri L Towe, Andrea L Hobkirk, Denis Nash, Renee D Goodwin
Little is known about cannabis use frequency, medical cannabis use, or correlates of use among persons living with HIV (PLWH) in United States nationally representative samples. Data came from 626 PLWH from the 2005-2015 National Survey on Drug Use and Health. Logistic regression identified characteristics associated with frequency of cannabis use. Chi-squares identified characteristics associated with medial cannabis use. Non-daily and daily cannabis use was reported by 26.9% and 8.0%. Greater perceived risk of cannabis use was negatively associated with daily and non-daily use...
April 2018: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/29688775/impacts-of-hiv-stigma-on-psychosocial-well-being-and-substance-use-behaviors-among-people-living-with-hiv-aids-in-china-across-the-life-span
#19
Chen Zhang, Xiaoming Li, Yu Liu, Yuejiao Zhou, Zhiyong Shen, Yi Chen
To date, existing studies have indicated that stigma against people living with HIV/AIDS (PLWHA) negatively affects their psychosocial well-being, and the impact may differ by age. In the current study, we aim to assess the impact of various types of stigma on PLWHA's psychological status and concomitant substance use. We explored different types of HIV stigma with psychosocial well-being and substance use employing mixed effect models among 2,987 Chinese PLWHA. Multivariate analyses revealed that each type of HIV stigma is positively associated with psychosocial distress, but negatively related to resilience and self-esteem across all age groups of PLWHA, with enacted stigma showing the strongest impact...
April 2018: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/29688733/drug-use-for-secondary-prevention-of-cardiovascular-diseases-in-golestan-iran-results-from-the-golestan-cohort-study
#20
Mahdi Nalini, Sadaf G Sepanlou, Akram Pourshams, Hossein Poustchi, Maryam Sharafkhah, Hossein Bahrami, Farin Kamangar, Reza Malekzadeh
BACKGROUND: Little is known about secondary prevention of cardiovascular diseases, using cardio-protective drugs, in the community-level, especially in low- and middle-income countries. We aimed to assess main drug use and its predictors in Northeast of Iran. METHODS: This is a cross-sectional analysis on the Golestan Cohort Study data (2004-2008) with 50 045 participants. We assessed drug use in those with a history of ischemic heart disease (IHD) or stroke, recorded by face-to-face interviews...
March 1, 2018: Archives of Iranian Medicine
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