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Bone densitometry

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https://www.readbyqxmd.com/read/29049519/association-of-bone-mineral-density-with-the-risk-of-intracranial-aneurysm
#1
Yong-Won Shin, Kyung-Il Park, Jangsup Moon, Soon-Tae Lee, Kon Chu, Sang Kun Lee, Jae-Kyu Roh, Keun-Hwa Jung
Importance: Disruption of extracellular matrix integrity is critically involved in both intracranial aneurysm and bone fragility. Furthermore, both intracranial aneurysm and osteoporosis have a female predominance, and sex hormones are considered to affect this discrepancy. Objective: To evaluate the association between bone mineral density and intracranial aneurysm. Design, Setting, and Participants: A cross-sectional study conducted with 14 328 patients who underwent brain magnetic resonance angiography and bone mineral densitometry as a part of a health examination at a specialized center for comprehensive health examination in Seoul, the largest metropolitan area in the Republic of Korea, between December 2004 and November 2015...
October 16, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29044313/evaluation-of-the-anti-osteoporotic-effect-of-ginkgo-biloba-l-in-wistar-rats-with-glucocorticoid-induced-osteoporosis-by-bone-densitometry-using-dual-energy-x-ray-absorptiometry-dexa-and-mechanical-testing
#2
Leda M F Lucinda, Beatriz J V Aarestrup, Maycon M Reboredo, Thais D A Pains, Raphael Z Chaves, João E P Reis, Mário J Q Louzada, Martha O Guerra
Evaluate the effect of the extract of Ginkgo biloba in the bone alkaline phosphatase, bone mineral density, in the mechanical properties of the tibia in rats with glucocorticoid-induced-osteoporosis. After osteoporosis induction, the rats were divided into five groups: Osteoporosis; EGb1 (28 mg/Kg); EGb2 (56 mg/Kg); alendronate (0.2 mg/animal) and control. The animals were treated during 20 and 30 days. The control group was compared with the osteoporosis's (Student's t-test), while the other were analyzed by ANOVA test followed by Tukey/Dunnett'T3 (p<0...
October 16, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29038394/factors-associated-with-lumbar-and-femoral-bone-mineral-density-in-kidney-transplants-candidates
#3
Mohammad Aghighi, Mitra Mahdavi Mazdeh, Mohsen Nafar, Vahid Rakhshan
INTRODUCTION: Data on risk factors associated with low bone mineral density are limited in patients with end-stage renal disease. This study evaluated the factors deemed associated with lumbar and femoral Z and T scores. MATERIALS AND METHODS: Clinical and demographic data of 98 patients waiting for kidney transplantation were collected, as well as lumbar and femoral bone densitometries, before transplantation. Osteoporosis and osteopenia and factors associated with bone mineral density were assessed...
October 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/29036996/-analysis-of-prevalence-and-related-factors-of-osteoporosis-in-retired-population-based-on-dongfeng-tongji-cohort
#4
H Yan, X Z Liu, Y Z Zhang, M A He, T C Wu
Objective: To investigate the prevalence and related factors of osteoporosis among retired population in Dongfeng-Tongji cohort. Methods: 27 009 retired participants were recruited from Dongfeng Motor Corporation in Hubei Province in 2008 and followed up from April to October in 2013. newly retired participants also were recruited. Data were collected by using questionnaire, physical examination, serum hepatase detection and bone densitometry. Totally, 30 916 participants were included for data analysis after excluding participants with severe bone metabolic diseases, taking hormone drugs, incomplete follow-up data and who were under 45 years old...
October 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29034241/bone-mineral-density-after-weight-gain-in-160-patients-with-anorexia-nervosa
#5
Najate Achamrah, Moïse Coëffier, Pierre Jésus, Jocelyne Charles, Agnès Rimbert, Pierre Déchelotte, Sébastien Grigioni
Low bone mineral density (BMD) is a frequent complication in anorexia nervosa (AN). There are controversial points of views regarding the restoration of bone mineralization after recovery in AN. We aimed to assess changes of BMD at 3 years in patients with AN and to explore the relationships between body composition, physical activity, and BMD. Patients with AN were included from 2009 to 2011 in a first visit (T0) with evaluation of weight, height, body mass index (BMI), body composition [fat mass (FM) and fat-free mass], and BMD...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29032291/impact-of-an-osteoporosis-specialized-unit-on-bone-health-in-breast-cancer-survivals-treated-with-aromatase-inhibitors
#6
Purificación Martínez, Elena Galve, Virginia Arrazubi, M Ángeles Sala, Seila Fernández, Clara E Pérez, Juan F Arango, Iñaki Torre
OBJECTIVE: Considering the increased fracture risk in early breast cancer patients treated with aromatase inhibitors (AI), we assessed the impact of a preventive intervention conducted by a specialized osteoporosis unit on bone health at AI treatment start. MATERIAL AND METHODS: Retrospective cohort of postmenopausal women who started treatment with AI after breast cancer surgical/chemotherapy treatment and were referred to the osteoporosis unit for a comprehensive assessment of bone health...
October 11, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/29018567/do-we-need-bone-mineral-density-to-estimate-osteoporotic-fracture-risk-a-10-year-prospective-multicentre-validation-study
#7
Andréa Marques, Raquel Lucas, Eugénia Simões, Suzanne M M Verstappen, Johannes W G Jacobs, Jose A P da Silva
OBJECTIVE: Evaluate the performance of FRAX®, with and without bone mineral densitometry (BMD), in predicting the occurrence of fragility fractures over 10 years. METHODS: Participants aged ≥40 years at baseline, with a complete set of data and a minimum of 8.5 years of follow-up were identified from three cohorts (n=2626). Ten-year fracture risk at baseline were estimated with FRAX® and assessed by comparison with observed fractures and receiver operating characteristic analysis...
2017: RMD Open
https://www.readbyqxmd.com/read/28977305/assessment-of-the-late-effects-on-bones-and-on-body-composition-of-children-and-adolescents-treated-for-acute-lymphocytic-leukemia-according-to-brazilian-protocols
#8
Poliana Cristina Carmona Molinari, Henrique Manoel Lederman, Maria Lucia de Martino Lee, Eliana Maria Monteiro Caran
OBJECTIVE: To evaluate the impact of therapy on bone mineral density (BMD) and body composition in survivors of acute lymphoblastic leukemia (ALL) treated in accordance with Brazilian protocols by the Brazilian Cooperative Group of Treatment of Lymphoblastic Leukemia in Childhood (GBTLI) LLA-93 and LLA-99. METHODS: A cross-sectional study with 101 patients was performed. BMD and body composition were evaluated using bone densitometry and were interpreted according to the age group and the reference population...
January 2017: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/28968828/homeostatic-expansion-of-cd4-t-cells-promotes-cortical-and-trabecular-bone-loss-while-cd8-t-cells-induce-trabecular-bone-loss-only
#9
M Neale Weitzmann, Tatyana Vikulina, Susanne Roser-Page, Masayoshi Yamaguchi, Ighovwerha Ofotokun
Background: Bone loss occurs in HIV infection, but paradoxically is intensified by HIV-antiretroviral therapy (ART) causing increased fracture incidence that is largely independent of antiretroviral regimen. Inflammation in the bone microenvironment associated with T-cell repopulation following ART-initiation, may explain ART-induced bone loss. Indeed, we have reported that reconstitution of CD3+ T-cells in immunodeficient mice, mimics ART-induced bone loss observed in humans. In this study, we quantified the relative effects of CD4+ and CD8+ T-cell subsets on bone...
August 25, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28954488/the-peripheral-quantitative-computed-tomographic-and-densitometric-analysis-of-skeletal-tissue-in-male-wistar-rats-after-chromium-sulfate-treatment
#10
Marek Bieńko, Radosław Piotr Radzki, Dariusz Wolski
INTRODUCTION: This study evaluates the effects of three different doses of chromium sulphate on bone density and the tomographic parameters of skeletal tissue of rats. MATERIAL AND METHODS: The experiment was performed on 40 male Wistar rats which received, by gavage, during 90 days, a chromium sulphate in either a daily dose of 400, 600 or 800 µg/kg BW. At the end of experiment, the rats were scanned using the densitometry method (DXA) to determine the bone mineral density, bone mineral content of total skeleton and vertebral column (L2-L4) and parameters of body composition (Lean Mass and Fat Mass)...
September 21, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28935593/factors-affecting-peri-implant-fracture-following-locking-plate-for-osteoporotic-distal-femur-fractures
#11
Ki-Chul Park, Seung-Jae Lim, Young Sik Song, Kyu-Tae Hwang
INTRODUCTION: The purpose of this study is to evaluate the outcomes and to analyze the risk factors for the occurrence of peri-implant fracture after treatment of osteoporotic distal femoral fracturesusing a locking plate. HYPOTHESIS: Risk factors affecting peri-implant fracture exist after locking plate fixation in osteoporotic distal femur fracture. MATERIALS AND METHODS: Eighty nine(88 patients) with osteoporotic distal femoral fractures were evaluated between January2006 and January2014...
September 18, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28922726/chronic-arsenicosis-and-cadmium-exposure-in-wild-snowshoe-hares-lepus-americanus-breeding-near-yellowknife-northwest-territories-canada-part-2-manifestation-of-bone-abnormalities-and-osteoporosis
#12
S Amuno, A Al Kaissi, A Jamwal, S Niyogi, C E Quenneville
Various bone abnormalities, including osteoporosis, have been associated with chronic arsenic and cadmium exposure in experimental animal models, but information regarding the bone pathology of wild population of small mammals breeding in contaminated environment is limited. This present study was conducted to comparatively assess the prevalence and pattern of skeletal abnormalities in free ranging snowshoe hares inhabiting an area heavily contaminated by arsenic and other trace metals, near the vicinity of the abandoned Giant mine, and in a reference location approximately 20km from the city of Yellowknife, Northwest Territories, Canada...
September 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28919366/prevalence-and-risk-factors-for-fragility-fracture-in-systemic-mastocytosis
#13
Yannick Degboé, Marine Eischen, Delphine Nigon, Pol-André Apoil, Claire Mailhol, Emilie Tournier, Camille Laurent, Katia Hanssens, Olivier Hermine, Carle Paul, Michel Laroche, Cristina Bulai-Livideanu
OBJECTIVES: Systemic mastocytosis (SM) is characterized by the accumulation of mast cells in tissues other than the skin. Bone involvement although frequent has not been thoroughly evaluated. Primary objective was to determine risk factors associated with fragility fractures (FF) in SM. Secondary objectives were to evaluate the ability of bone marrow tryptase (BMT) level to identify patients with FF, and to describe bone involvement in SM. METHODS: We analyzed retrospectively all consecutive patients seen in our expert center, with a diagnosis of SM according to the 2001 WHO criteria, and with complete bone assessment...
September 14, 2017: Bone
https://www.readbyqxmd.com/read/28860112/risk-factors-for-falls-in-older-patients-with-cancer
#14
Xiaotao Zhang, Ming Sun, Suyu Liu, Cheuk Hong Leung, Linda Pang, Uday R Popat, Richard Champlin, Holly M Holmes, Vicente Valero, Colin P Dinney, Debu Tripathy, Beatrice J Edwards
OBJECTIVES: A rising number of patients with cancer are older adults (65 years of age and older), and this proportion will increase to 70% by the year 2020. Falls are a common condition in older adults. We sought to assess the prevalence and risk factors for falls in older patients with cancer. METHODS: This is a single-site, retrospective cohort study. Patients who were receiving cancer care underwent a comprehensive geriatric assessments, including cognitive, functional, nutritional, physical, falls in the prior 6 months and comorbidity assessment...
August 31, 2017: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/28853593/changes-in-bone-turnover-markers-in-primary-hyperparathyroidism-and-response-to-surgery
#15
P Rajeev, A Movseysan, A Baharani
Introduction Involvement of the bone is common in primary hyperparathyroidism. The aim of the study was to assess bone turnover markers in response to surgery for primary hyperparathyroidism. Methods This was a retrospective study of patients diagnosed and treated for parathyroid disease between 2005 and 2012. Interventions studied were surgery and medical treatment. The main outcome measures studied were serum levels of calcium, intact parathyroid hormone (iPTH), bone-specific alkaline phosphatase, N-terminal cross-linking propeptide of type 1 procollagen (P1NP) and C-terminal cross-linking telopeptides of type I collagen (CTX), both pre- and postoperatively at 6 months and 1 year; bone mineral density (at the spine and hip assessed by dual-energy x-ray absorptiometry after 1 year of treatment...
September 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28835759/associated-factors-of-bone-mineral-density-and-osteoporosis-in-elderly-males
#16
Behzad Heidari, Abdollah Muhammadi, Yahya Javadian, Ali Bijani, Reza Hosseini, Mansour Babaei
BACKGROUND: Low bone mineral density and osteoporosis is prevalent in elderly subjects. This study aimed to determine the associated factors of bone mineral density and osteoporosis in elderly males. METHODS: All participants of the Amirkola health and ageing project cohort aged 60 years and older entered the study. Bone mineral density at femoral neck and lumbar spine was assessed by the dual energy X-ray absorptiometry (DXA) method. Osteoporosis was diagnosed by the international society for clinical densitometry criteria and the association of bone mineral density and osteoporosis with several clinical, demographic and biochemical parameters...
January 2017: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28802981/errors-in-patient-positioning-for-bone-mineral-density-assessment-by-dual-x-ray-absorptiometry-effect-of-technologist-retraining
#17
Sasivimol Promma, Chanika Sritara, Saowanee Wipuchwongsakorn, Krisanat Chuamsaamarkkee, Chirawat Utamakul, Wichana Chamroonrat, Arpakorn Kositwattanarerk, Yoch Anongpornjossakul, Kanungnij Thamnirat, Boonsong Ongphiphadhanakul
Improper positioning is one of the factors that can lead to incorrect bone mineral density (BMD) results. This study aimed to assess the frequencies of erroneous positioning during three periods: before retraining of the technologists (BR), after retraining (AR), and at the current timepoint 8 years after retraining (C). The BMD images of the first 150 consecutive patients who underwent DXA of the lumbar spine and hip during each of the three periods were retrospectively reviewed. Patients were excluded if they had severe scoliosis, rendering proper positioning impossible...
August 9, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28798322/luciferase-expression-allows-bioluminescence-imaging-but-imposes-limitations-on-the-orthotopic-mouse-4t1-model-of-breast-cancer
#18
V P Baklaushev, A Kilpeläinen, S Petkov, M A Abakumov, N F Grinenko, G M Yusubalieva, A A Latanova, I L Gubskiy, F G Zabozlaev, E S Starodubova, T O Abakumova, M G Isaguliants, V P Chekhonin
Implantation of reporter-labeled tumor cells in an immunocompetent host involves a risk of their immune elimination. We have studied this effect in a mouse model of breast cancer after the orthotopic implantation of mammary gland adenocarcinoma 4T1 cells genetically labelled with luciferase (Luc). Mice were implanted with 4T1 cells and two derivative Luc-expressing clones 4T1luc2 and 4T1luc2D6 exhibiting equal in vitro growth rates. In vivo, the daughter 4T1luc2 clone exhibited nearly the same, and 4T1luc2D6, a lower growth rate than the parental cells...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28781228/assessment-of-the-bone-mineral-content-in-the-mandible-by-dual-energy-x-ray-absorptiometry-to-evaluate-short-term-change
#19
Yun Sun, Min Min An, Jingmei Wang, Fan Yang, Liying He, Chad A Dudzek, Congjin Liu, Patrick C Cunniff, Xingdang Liu, Tom V Sanchez
With the objective of being able to assess response to disease or clinical treatment, the densitometry community has long sought the ability to assess short-term change in bone density. The mandible, known to have a high bone turnover, an increased vascularity, and a greater susceptibility to osteoclastic and osteoblastic activities, has long been suggested but has fallen short as a site from which to monitor an early change in the response to a treatment or a disease. The current study developed a method to assess bone density in the superimposed left and right mandibles...
August 3, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28766134/bone-health-in-long-term-gastric-cancer-survivors-a-prospective-study-of-high-dose-vitamin-d-supplementation-using-an-easy-administration-scheme
#20
Marta Climent, Manuel Pera, Isabel Aymar, José M Ramón, Luis Grande, Xavier Nogués
Bone disease in long-term survivors after gastric cancer resection has received little research attention. This study aimed to investigate bone health after curative resection of gastric cancer and the consequences of high-dose vitamin D supplementation in patients with low levels of 25-(OH)-vitamin D. Disease-free patients at least 24 months after gastric cancer resection represented the study cohort. Serum markers of bone metabolism were assessed at baseline and at 3 and 12 months. Bone mineral density and presence of fractures were assessed by X-ray at baseline...
August 1, 2017: Journal of Bone and Mineral Metabolism
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