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https://www.readbyqxmd.com/read/29147883/clinical-and-radiological-diagnosis-of-gallstone-ileus-a-mini-review
#1
Liisa Chang, Minna Chang, Hanna M Chang, Aina I Chang, Fuju Chang
Gallstone ileus is a rare cause of bowel obstruction, which mainly affects the elderly population. The associated mortality is estimated to be up to 30%. The presentation of gallstone ileus is notoriously non-specific, and this often contributes to the delay in diagnosis. The diagnosis of gallstone ileus relies on a radiological approach, and herein we discuss the benefits and drawbacks of the use of different modalities of radiological imaging: plain abdominal films, computed tomography, magnetic resonance imaging, and ultrasound scanning...
November 16, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/29143087/factors-associated-with-premalignant-epithelial-changes-in-chronic-calculous-cholecystitis-a-case-control-study
#2
Muhibullah Bangash, Abdul Rehman Alvi, Noman Shahzad, Amir Hafeez Shariff, Roger Christopher Gill
INTRODUCTION: Gallstones are known to be associated with premalignant changes in the gallbladder epithelium that range from atypical hyperplasia, metaplasia, dysplasia to carcinoma. Recognition of factors associated with these changes in patients with gallstones can potentially be helpful in identifying patients to whom prophylactic cholecystectomy can be offered to reduce the chances of developing carcinoma. OBJECTIVE: To identify factors associated with premalignant epithelial changes including atypical hyperplasia, metaplasia, and dysplasia in gallbladder mucosa in patients with chronic calculus cholecystitis...
November 15, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29142480/case-of-familial-hyperlipoproteinemia-type-iii-hypertriglyceridemia-induced-acute-pancreatitis-role-for-outpatient-apheresis-maintenance-therapy
#3
Mohannad Abou Saleh, Emad Mansoor, Gregory S Cooper
Hypertriglyceridemic pancreatitis (HTGP) accounts for up to 10% of acute pancreatitis presentations in non-pregnant individuals and is the third most common cause of acute pancreatitis after alcohol and gallstones. There are a number of retrospective studies and case reports that have suggested a role for apheresis and insulin infusion in the acute inpatient setting. We report a case of HTGP in a male with hyperlipoproteinemia type III who was treated successfully with insulin and apheresis on the initial inpatient presentation followed by bi-monthly outpatient maintenance apheresis sessions for the prevention of recurrent HTGP...
October 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29137063/gallstone-ileus-displaying-the-typical-rigler-triad-and-an-occult-second-ectopic-stone-a-case-report
#4
Li Wang, Ping Dong, Yi Zhang, Bole Tian
RATIONALE: Gallstone ileus is a rare complication of cholecystolithiasis. It has a female predominance and can result in high mortality rates. PATIENT CONCERNS: A 71-year-old woman complaining of recurrent vomiting and vague epigastralgia for > 2 weeks presented to our department. DIAGNOSIS: Based on her physical examination, laboratory test results and radiographic findings (the typical Rigler's triad), she was diagnosed with gallstone ileus caused by multiple ectopic stones...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29133112/persistent-abdominal-pain-after-laparoscopic-cholecystectomy-is-associated-with-increased-healthcare-consumption-and-sick-leave
#5
Sarah Z Wennmacker, Marcel G W Dijkgraaf, Gert P Westert, Joost P H Drenth, Cornelis J H M van Laarhoven, Philip R de Reuver
BACKGROUND: Although, 33% to 40% of symptomatic gallstone patients reported persistent abdominal pain after laparoscopic cholecystectomy, there is no data on the burden of this pain to the healthcare system and society at large. This study determined healthcare consumption, sick leave, and costs in patients with persistent abdominal pain after laparoscopic cholecystectomy. Secondly, predictive factors for healthcare consumption were assessed. METHODS: This cross-sectional study included all 146 patients with persistent abdominal pain (patient-reported on Gastro-Intestinal Quality of Life Index (score 0-3) 24 weeks after laparoscopic cholecystectomy, derived from a previous prospective cohort...
November 10, 2017: Surgery
https://www.readbyqxmd.com/read/29132523/pancreatitis-and-pancreatic-cancer
#6
REVIEW
Anne Walling, Robert Freelove
Most cases of acute pancreatitis are related to gallstones. More than 80% resolve within a few days. The diagnosis is based on upper abdominal pain, elevated lipase and/or amylase, and transabdominal ultrasound findings. Management requires early aggressive hydration, pain control, nutritional support, and monitoring for progression. Patients who develop hypovolemia, systemic inflammatory response, pancreatic necrosis, and organ failure have high mortality, risk of recurrence, and progression to chronic pancreatitis (CP)...
December 2017: Primary Care
https://www.readbyqxmd.com/read/29132521/gallbladder-dysfunction-cholecystitis-choledocholithiasis-cholangitis-and-biliary-dyskinesia
#7
REVIEW
Thad Wilkins, Edward Agabin, Jason Varghese, Asif Talukder
The prevalence of gallstones is 10% to 15% in adults. Individuals with acute cholecystitis present with right upper quadrant pain, fever, and leukocytosis. Management includes supportive care and cholecystectomy. The prevalence of choledocholithiasis is 10% to 20%, and serious complications include cholangitis and gallstone pancreatitis. The goal of management in individuals with choledocholithiasis consists of clearing common bile duct stones. Acute ascending cholangitis is a life-threatening condition involving acute inflammation and infection of the common bile duct...
December 2017: Primary Care
https://www.readbyqxmd.com/read/29127549/preservation-of-the-celiac-branch-of-the-vagal-nerve-for-pylorus-preserving-gastrectomy-is-it-meaningful
#8
Haruna Furukawa, Manabu Ohashi, Michitaka Honda, Koshi Kumagai, Souya Nunobe, Takeshi Sano, Naoki Hiki
BACKGROUND: Preserving the hepatic and pyloric branches of the vagal nerve in laparoscopic pylorus-preserving gastrectomy (LPPG) is considered necessary to maintain the function of the pyloric cuff. However, the clinical benefits of preservation of the celiac branch of the vagal nerve (CBVN) remain unclear. METHODS: Of 391 patients who underwent LPPG for early gastric cancer, 116 patients in whom the CBVN was preserved (CBP group) and 58 patients in whom it was not preserved (non-CBP group) were selected through the propensity score-matching method...
November 10, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/29119003/novel-associations-of-bile-acid-diarrhoea-with-fatty-liver-disease-and-gallstones-a-cohort-retrospective-analysis
#9
Richard N Appleby, Jonathan D Nolan, Ian M Johnston, Sanjeev S Pattni, Jessica Fox, Julian Rf Walters
Background: Bile acid diarrhoea (BAD) is a common cause of chronic diarrhoea with a population prevalence of primary BAD around 1%. Previous studies have identified associations with low levels of the ileal hormone fibroblast growth factor 19 (FGF19), obesity and hypertriglyceridaemia. The aim of this study was to identify further associations of BAD. Methods: A cohort of patients with chronic diarrhoea who underwent (75)selenohomocholic acid taurate (SeHCAT) testing for BAD was further analysed retrospectively...
2017: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/29118564/sex-related-differences-in-predicting-choledocholithiasis-using-current-american-society-of-gastrointestinal-endoscopy-risk-criteria
#10
Ankit Chhoda, Deepanshu Jain, Shashideep Singhal
Background: American Society of Gastrointestinal Endoscopy (ASGE) criteria is widely used to predict probability of choledocholithiasis among patients with symptomatic gallstone disease but does not take sex into consideration. Methods: The cohort study included patients who underwent either endoscopic retrograde cholangiopancreatography or intraoperative cholangiography for suspected choledocholithiasis at our medical center. Clinical, laboratory and radiological data were collected for each patient and used to stratify them based on the ASGE risk criteria for choledocholithiasis...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29118437/the-relation-between-gallstone-disease-and-cardiovascular-disease
#11
Lai Lai Fan, Bai Hui Chen, Zhi Juan Dai
Gallstone disease (GD) is a common digestive disorder that shares many risk factors with cardiovascular disease (CVD). CVD is an important public health issue that encompasses a large percentage of overall mortality. Several recent studies have suggested an association between GD and CVD, while others have not. In this report, we present a meta-analysis of cohort studies to assess the association between GD and CVD. We included eight studies published from 1980 to 2017, including nearly one million participants...
November 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29117670/association-between-dietary-intake-and-postlaparoscopic-cholecystectomic-symptoms-in-patients-with-gallbladder-disease
#12
Yongju Shin, Dongho Choi, Kyeong Geun Lee, Ho Soon Choi, Yongsoon Park
Background/Aims: After cholecystectomy, patients have reported postcholecystectomic syndromes such as abdominal symptoms, dyspepsia, and diarrhea, which suggest a relationship between cholecystectomic symptoms and diet, although the details of this association remain unclear. The present study investigated the hypothesis that dietary intake of nutrients and foods was significantly associated with postcholecystectomic syndromes. Methods: Gallstone patients (n = 59) who underwent laparoscopic cholecystectomy were enrolled, and dietary intake and clinical parameters were assessed immediately postcholecystectomy and 3 months later...
November 10, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29115653/bridge-treatment-for-early-cholecystectomy-in-geriatric-patients-with-acute-cholecystitis-percutaneous-cholecystostomy
#13
Sezgin Zeren, Zülfü Bayhan, Cengiz Koçak, Uğur Kesici, Mehmet Korkmaz, Mehmet Fatih Ekici, Mustafa Cem Algın, Faik Yaylak
BACKGROUND: The main cause of acute cholecystitis (AC) is gallstones, and the incidence of gallstones in elderly patients is high. METHODS: In this study, we aimed to investigate the efficacy of percutaneous cholecystostomy (PC) before early cholecystectomy in geriatric patients with AC. This retrospective study included 85 patients undergoing laparoscopic or conventional cholecystectomy during early stage of calculous AC. RESULTS: All patients were over 65 years old and were divided into two groups: Group I, PC plus early cholecystectomy and Group II, only cholecystectomy without PC...
November 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29114226/metformin-use-correlates-with-reduced-risk-of-gallstones-in-diabetic-patients-a-12-year-follow-up-study
#14
Kuan-Fu Liao, Hsun-Yang Chuang, Shih-Wei Lai
Objective: Few studies are available on the association between gallstones and metformin use. The objective of the study was to determine whether metformin use is associated with gallstones. Methods: A population-based retrospective cohort study was conducted using the database of the Taiwan National Health Insurance Program. Subjects of newly diagnosed diabetes mellitus were included from 2002 to 2013. The metformin-exposure group was defined as ≥29 cumulative defined daily dose (DDD) of metformin use. The un-exposure group was defined as <29 cumulative DDD of metformin use...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29113145/associations-between-nut-consumption-and-health-vary-between-omnivores-vegetarians-and-vegans
#15
Rachel C Brown, Andrew R Gray, Siew Ling Tey, Alexandra Chisholm, Victoria Burley, Darren C Greenwood, Janet Cade
Regular nut consumption is associated with reduced risk factors for chronic disease; however, most population-based studies lack consideration of effect modification by dietary pattern. The UK Women's Cohort Study (UKWCS) provides an ideal opportunity to examine relationships between nut consumption and chronic disease risk factors in a large sample with diverse dietary patterns. Nut and nutrient intake from 34,831 women was estimated using a food frequency questionnaire among self-identified omnivores, vegetarians and vegans...
November 6, 2017: Nutrients
https://www.readbyqxmd.com/read/29101565/comparison-of-clinical-efficacies-and-safeties-of-lumen-apposing-metal-stent-and-conventional-type-metal-stent-assisted-eus-guided-pancreatic-wall-off-necrosis-drainage-a-real-life-experience-in-a-tertiary-hospital
#16
Siu Tong Law, Carlos De La SernaHiguera, Paula Gil Simón, Manuel Pérez-MirandaCastillo
BACKGROUND: Endoscopic ultrasound (EUS)-guided drainage of pancreatic wall-off necrosis (WON) with transmural stent is regarded as firstline therapy. We aimed at comparing its efficacy and safety with using fully covered self-expandable metal stent (FCSEMS) and lumen-apposing metal stent (LAMS). METHODS: A retrospective review was performed on all consecutive patients with pancreatic WONs who underwent EUS-guided drainage by either FCSEMS or LAMS. RESULTS: From 2011 to 2016, 68 patients (66...
November 3, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29100225/acute-pancreatitis-etiology-pathology-diagnosis-and-treatment
#17
Shirin Majidi, Adam Golembioski, Stephen L Wilson, Errington C Thompson
Acute pancreatitis is a fascinating disease. In the United States, the two most common etiologies of acute pancreatitis are gallstones and excessive alcohol consumption. The diagnosis of acute pancreatitis is made with a combination of history, physical examination, computed tomography scan, and laboratory evaluation. Differentiating patients who will have a benign course of their pancreatitis from patients who will have severe pancreatitis is challenging to the clinician. C-reactive protein, pro-calcitonin, and the Bedside Index for Severity of Acute Pancreatitis appeared to be the best tools for the early and accurate diagnosis of severe pancreatitis...
November 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/29092966/use-of-emergency-department-point-of-care-ultrasound-in-a-case-of-cholecystitis
#18
Nicolas Lim, Aileen McCabe, John Cronin
A 54-year-old man presented with severe right upper quadrant (RUQ) abdominal pain. He denied any infective symptoms. On clinical examination, he was afebrile and anicteric. His abdomen was soft with tenderness elicited on the RUQ. A point-of-care ultrasound in the emergency department demonstrated a distended gallbladder with a thickened wall and an impacted large gallstone at the neck of the gallbladder. Furthermore, the point-of-care ultrasound also identified a highly reflective echo from the anterior surface of the gallstone and marked posterior acoustic shadowing...
November 1, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29089735/role-of-tranexamic-acid-on-blood-loss-in-laparoscopic-cholecystectomy
#19
Paras Kumar Pandove, Rachan Lal Singla, Pallavi Mittal, Nikhil Mahajan, Ashwani Kumar
CONTEXT: Nonsurgical uses of tranexamic acid include the management of bleeding associated with leukemia, ocular bleeding, recurrent hemoptysis, menorrhagia, hereditary angioneurotic edema, and numerous other medical problems. However, there is hardly any documentation of the use of tranexamic acid in laparoscopic cholecystectomy. AIMS: This study was conducted to evaluate the role of tranexamic acid in limiting blood loss in laparoscopic cholecystectomy and to evaluate the effect of blood loss on morbidity in terms of hospital stay and mortality of the patient...
July 2017: Nigerian Journal of Surgery: Official Publication of the Nigerian Surgical Research Society
https://www.readbyqxmd.com/read/29082890/acute-pancreatitis-after-coronary-artery-bypass-surgery-treated-by-plasmapheresis
#20
Emine Şeyma Denli Yalvaç, Mustafa Aldağ, Cemal Kocaaslan, Ebubekir Şenateş, Ebuzer Aydın
Acute pancreatitis (AP) is a common disorder and an important cause of morbidity and mortality. There are different causes of AP, including gallstones and excessive alcohol consumption. AP after coronary artery bypass grafting (CABG) surgery is seen less frequently but it is associated with a high mortality rate due to its atypical and misleading symptoms. Supportive treatment, pain management, and treatment of complications are used in the treatment of AP. The treatment of hypertriglyceridemia-induced pancreatitis is plasmapheresis, which is an extracorporeal separation of blood components to assist in the removal of inflammatory mediators...
October 30, 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
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