Edward Christopher Dee, Victor C Ng, Eileen M O'Reilly, Alice C Wei, Stephanie M Lobaugh, Anna M Varghese, Melissa Zinovoy, Paul B Romesser, Abraham J Wu, Carla Hajj, John J Cuaron, Danny N Khalil, Wungki Park, Kenneth H Yu, Zhigang Zhang, Jeffrey A Drebin, William R Jarnagin, Christopher H Crane, Marsha Reyngold
Introduction: The rate of isolated locoregional recurrence after surgery for pancreatic adenocarcinoma (PDAC) approaches 25%. Ablative radiation therapy (A-RT) has improved outcomes for locally advanced disease in the primary setting. We sought to evaluate the outcomes of salvage A-RT for isolated locoregional recurrence and examine the relationship between subsequent patterns of failure, radiation dose, and treatment volume. Methods : We conducted a retrospective analysis of all consecutive participants who underwent A-RT for an isolated locoregional recurrence of PDAC after prior surgery at our institution between 2016 and 2021...
April 30, 2024: Journal of Clinical Medicine