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qi gong

Quanwei Zhang, Qi Wang, Jishang Gong, Jiaxing Du, Yong Zhang, Xingxu Zhao
Insulin-like growth factor 2 (IGF2) recapitulates many of the activities of insulin and promotes differentiation of myoblasts and osteoblasts, which likely contribute to genetic variations of growth potential. However, little is known about the functions and signaling properties of IGF2 variants in yaks. The over-expression vector and knockdown sequence of yak IGF2 were transfected into yak fibroblasts, and the effects were detected by a series of assays. IGF2 expression in yak muscle tissues was significantly lower than that of other tissues...
March 20, 2018: Genes
Jiao Ji, Yan Yu, Zhi-Ling Li, Ming-Yuan Chen, Rong Deng, Xiang Huang, Guang-Feng Wang, Meng-Xia Zhang, Qi Yang, Senthilkumar Ravichandran, Gong-Kan Feng, Xue-Lian Xu, Chen-Lu Yang, Miao-Zhen Qiu, Lin Jiao, Dajun Yang, Xiao-Feng Zhu
Rationale: Nasopharyngeal carcinoma (NPC) is the most frequent head and neck tumor in South China. The presence of cancer stem cells (CSCs) in NPC contributes to tumor maintenance and therapeutic resistance, while the ability of CSCs to escape from the apoptosis pathway may render them the resistant property to the therapies. Inhibitor of apoptosis proteins family proteins (IAPs), which are overexpressed in nasopharyngeal carcinoma stem cells, may play an important role in maintaining nasopharyngeal cancer stem cell properties...
2018: Theranostics
Lixia Fu, Jing Guan, Yujia Zhang, Pei Ma, Yuanyuan Zhuang, Jinye Bai, Yasi Ding, Qi Hou, Wan Gong, Mingbao Lin, Wensheng Zheng, Jianmin Zhang
Background: Tulobuterol patch, one of strongest bronchodilators, was recently shown to improve bronchial hyperresponsiveness and significantly decrease the sputum eosinophil counts by combining with nonspecific anti-inflammatory drugs on patients with asthma. However, there is limited study on the anti-inflammatory activities of tulobuterol patch and its potential machenism. Results: The tulobuterol patch significantly ameliorated inflammatory cell infiltration in the lung tissue, reduced the number of total leukocytes and its differential count, markedly reduced the production of IL-1β, TNF-α, IL-6, CCL-11 and IL-4 in bronchial alveolar lavage fluid, as well as a reduction in IL-4/IFN-γ ratio...
February 23, 2018: Oncotarget
Qiuyun Fang, Tian Yuan, Yan Li, Juan Feng, Xiaoyuan Gong, Qinghua Li, Xingli Zhao, Kaiqi Liu, Kejing Tang, Zheng Tian, Qi Zhang, Ying Wang, Bingcheng Liu, Min Wang, Kun Ru, Jianxiang Wang, Yingchang Mi
The multiplex ligation-dependent probe amplification (MLPA) method was used to detect the copy number alterations (CNAs) of IKAROS family zinc finger 1 ( IKZF1 ), paired box 5 ( PAX5 ), ETS variant 6 ( ETV6 ), RB transcriptional corepressor 1 ( RB1 ), BTG anti-proliferation factor 1 ( BTG1 ), early B-cell factor 1 ( EBF1 ), cyclin dependent kinase inhibitor 2A/2B ( CDKN2A/2B ) and cytokine receptor like factor 2 ( CRLF2 ) genes in 87 adults with acute lymphoblastic leukemia (ALL) in China. The effects of CNAs on prognosis were analyzed...
April 2018: Oncology Letters
Qi Sui, Peng Li, Ning-Ning Yang, Teng Gong, Ran Bu, En-Qing Gao
Since amines have high toxicity and exist widely, the development of selective sensing materials for amine detection has received considerable attentions. In this article, we demonstrate for the first time that a degree of discriminative detection of alkylamines can be achieved by a metal-organic coordination material. The material is derived from CdII and 4,4'-bipyridinium-1,1'-bis(phenylene-3-carboxylate), shows 1D channels lined with electron-deficient viologen chromophores, and exhibits different colors upon contact with amine vapors of different molecular sizes and types (primary, secondary and tertiary)...
March 16, 2018: ACS Applied Materials & Interfaces
Ding Peng, Cui-Jian Zhang, Qi Tang, Lei Zhang, Kai-Wei Yang, Xiao-Teng Yu, Yanqing Gong, Xue-Song Li, Zhi-Song He, Li-Qun Zhou
BACKGROUND: To evaluate the prognostic significance of the novel index combining preoperative hemoglobin and albumin levels and lymphocyte and platelet counts (HALP) in renal cell carcinoma (RCC) patients. METHODS: We enrolled 1360 patients who underwent nephrectomy in our institution from 2001 to 2010. The cutoff values for HALP, neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio were defined by using X-tile software. Survival was analyzed by the Kaplan-Meier method, with differences analyzed by the log-rank test...
March 15, 2018: BMC Urology
Wu-Qi Qiu, Ju-Fang Shi, Lan-Wei Guo, A-Yan Mao, Hui-Yao Huang, Guang-Yu Hu, Pei Dong, Fang-Zhou Bai, Xiao-Ling Yan, Xian-Zhen Liao, Guo-Xiang Liu, Ya-Na Bai, Jian-Song Ren, Xiao-Jie Sun, Xin-Yu Zhu, Jin-Yi Zhou, Ji-Yong Gong, Lin Zhu, Ling Mai, Ling-Bing Du, Qi Zhou, Xiao-Jing Xing, Bing-Bing Song, Yu-Qin Liu, Pei-An Lou, Xiao-Hua Sun, Shou-Ling Wu, Rong Cao, Xiao Qi, Li Lan, Ying Ren, Kai Zhang, Jie He, Chunfeng Qu, Min Dai
Objective: This study aims to understand the medical expenditure for liver cancer during 2002-2011 in urban areas of China. Materials and Methods: This is a retrospective study. Based on a stratified cluster sampling method, a medical expenditure survey collected basic personal information from related medical records. Two-tailed independent sample t-test, variance analysis, and Student-Newman-Keuls Tests were used in cost analysis for the corresponding data types...
January 2018: Journal of Cancer Research and Therapeutics
Xin-Bo Ai, Zhen-Jiang Wang, Qi-Chao Dong, Xu Lin, Yu-Ping Chen, Fei-Yue Gong, Hui Liang
Gastrointestinal histoplasmosis (GIH) without pulmonary and bone marrow involvement is very rare worldwide. It can be misdiagnosed as intestinal tuberculosis or Crohn's disease. There are just few case reports of GIH in patients with a positive HIV antibody test. Here, we report a patient who presented to our hospital with repeated intestinal obstruction. The suspicious diagnosis was intestinal tuberculosis or Crohn's disease due to unspecific clinical manifestations and radiologic images. Our patient's HIV antibody test was negative...
January 2018: Case Reports in Gastroenterology
Dongmei Lin, Aihua Zhang, Jason Gu, Xiaolei Chen, Qi Wang, Liming Yang, Yongxin Chou, Gongcai Liu, Jingyang Wang
BACKGROUND AND OBJECTIVE: Pulse signals contain a wealth of human physiological and pathological information. How to get full pulse information is especially challenging, and most of the traditional pulse sensors can only get the pulse wave of a single point. This study is aimed at developing a binocular pulse detection system and method to obtain multipoint pulse waves and dynamic three-dimensional pulse shape of the radial artery. METHODS: The proposed pulse detection approach is image-based and implemented by two steps...
March 2018: Computer Methods and Programs in Biomedicine
Xuewen Wei, JuanJuan Gong, Juyun Ma, Taiyu Zhang, Yihang Li, Ting Lan, Peng Guo, Suhua Qi
It is well known that Wnt5a activation plays a pivotal role in brain injury and β-arrestin2 induces c-Jun N-terminal kinase (JNK3) activation is involved in neuronal cell death. Nonetheless, the relationship between Wnt5 and JNK3 remains unexplored during cerebral ischemia/reperfusion (I/R). In the present study, we tested the hypothesis that Wnt5a-mediated JNK3 activation via the Wnt5a- Dvl-1-β-arrestin2-JNK3 signaling pathway was correlated with I/R brain injury. We found that cerebral I/R could enhance the assembly of the Dvl-1-β-arrestin2-JNK3 signaling module, Dvl-1 phosphorylation and JNK3 activation...
March 3, 2018: Neuropharmacology
Fei-Fei Zhang, Wei Peng, John A Sweeney, Zhi-Yun Jia, Qi-Yong Gong
Depression is the leading cause of disability around the world, but little is known about its pathology. Currently, the diagnosis of depression is made based on clinical manifestations, with little objective evidence. Magnetic resonance imaging (MRI) has been used to investigate the pathological changes in brain anatomy associated with this disorder. MRI can identify structural alterations in depressive patients in vivo, which could make considerable contributions to clinical diagnosis and treatment. Numerous studies that focused on gray and white matter have found significant brain region alterations in major depressive disorder patients, such as in the frontal lobe, hippocampus, temporal lobe, thalamus, striatum, and amygdala...
March 5, 2018: CNS Neuroscience & Therapeutics
Lin Jin, Xiaomin Guo, Chuanbin Shen, Xue Hao, Peng Sun, Pengpeng Li, Tao Xu, Chunmiao Hu, Ombati Rose, Hongning Zhou, Mingdong Yang, Cheng-Feng Qin, Jingya Guo, Hua Peng, Mingzhao Zhu, Gong Cheng, Xiaopeng Qi, Ren Lai
Pathogens have co-evolved with mosquitoes to optimize transmission to hosts. Mosquito salivary-gland extract is known to modulate host immune responses and facilitate pathogen transmission, but the underlying molecular mechanisms of this have remained unknown. In this study, we identified and characterized a prominent 15-kilodalton protein, LTRIN, obtained from the salivary glands of the mosquito Aedes aegypti. LTRIN expression was upregulated in blood-fed mosquitoes, and LTRIN facilitated the transmission of Zika virus (ZIKV) and exacerbated its pathogenicity by interfering with signaling through the lymphotoxin-β receptor (LTβR)...
March 5, 2018: Nature Immunology
Soohyun Kim, Lawrence Chang, Bianca Weinstock-Guttman, Sirin Gandhi, Dejan Jakimovski, Ellen Carl, Robert Zivadinov, Murali Ramanathan
OBJECTIVES: To investigate the factors associated with complementary and alternative medicine (CAM) usage by multiple sclerosis (MS) patients. Design, Setting/Location: Single-center, prospective clinical study at an academic MS center in the northeastern United States. METHODS: This study included CAM data from 524 MS patients and 304 healthy controls (HC) enrolled in a prospective study of clinical, neuroimaging, and environmental risk factors in MS at an academic MS Center...
March 2, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
P Dong, W Q Qiu, J F Shi, A Y Mao, H Y Huang, Z X Sun, J W Huang, X Z Liao, G X Liu, D B Wang, Y N Bai, X J Sun, J S Ren, L W Guo, L Lan, Y Q Liu, J Y Gong, L Yang, X J Xing, B B Song, Q Zhou, L Mai, L Zhu, L B Du, Y Z Zhang, J Y Zhou, M F Qin, S L Wu, X Qi, X H Sun, P A Lou, B Cai, K Zhang, J He, M Dai
Objective: To explore the sustainability of cancer screening strategy from potential demander's perspective in Chinese country, we conducted a study on the use of cancer screening services and willingness-to-pay among the urban community residents. All the participants of this study had not been on the Cancer Screening Program in Urban China (CanSPUC) or any other national level cancer screening projects. Methods: Target communities and populations were selected from the 16 project provinces in China which were on the program between 2014 and 2015, by using the multi-center cross-sectional convenience sampling method...
February 10, 2018: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
Qi-Zhe Gong, Di Xiao, Feng Feng, Xiao-Dong Wen, Wei Qu
Ent-sauchinone, a lignan isolated from Saururus chinensis (Lour.) Bail, was reported that it could modulate the expression of Signal transducer and activator of transcription 3 (STAT3). Since STAT3 plays a key role in invasion, migration and metastasis of cancer, we investigated whether ent-sauchinone could exert promising inhibitory effects on the invasion and migration of the metastatic human liver cancer cell line SMMC-7721 in the present study. Ent-sauchinone was extracted from dried herbs of Saururus chinensis (Lour...
March 1, 2018: Chemistry & Biodiversity
Xiaoguang Cao, Peng Wang, Cai Meng, Xiangzhi Bai, Guoping Gong, Miaoming Liu, Jun Qi
In this paper, a novel algorithm based on convolutional neural network (CNN) is proposed to detect foreign object debris (FOD) based on optical imaging sensors. It contains two modules, the improved region proposal network (RPN) and spatial transformer network (STN) based CNN classifier. In the improved RPN, some extra select rules are designed and deployed to generate high quality candidates with fewer numbers. Moreover, the efficiency of CNN detector is significantly improved by introducing STN layer. Compared to faster R-CNN and single shot multiBox detector (SSD), the proposed algorithm achieves better result for FOD detection on airfield pavement in the experiment...
March 1, 2018: Sensors
Jilei Zhang, Li Chen, Jiawei Wang, Afrah Kamal Yassin, Patrick Butaye, Patrick Kelly, Jiansen Gong, Weina Guo, Jing Li, Min Li, Feng Yang, Zhixing Feng, Ping Jiang, Chunlian Song, Yaoyao Wang, Jinfeng You, Yi Yang, Stuart Price, Kezong Qi, Yuan Kang, Chengming Wang
Antimicrobial resistance against colistin has emerged worldwide and is threatening the efficacy of colistin treatment of multi-resistant Gram-negative bacteria. In this study, PCRs were used to detect mcr genes (mcr-1, mcr-2, mcr-3) in 213 anal and 1,339 nasal swabs from pigs (n = 1,454) in nine provinces of China, and 1,696 cloacal and 1,647 oropharyngeal samples from poultry (n = 1,836) at live-bird markets in 24 provinces. The mcr-1 prevalences in pigs (79.2%) and geese (71.7%) were significantly higher than in chickens (31...
February 27, 2018: Scientific Reports
Ji Qi, Shaoqun Zhang, Lei Zhang, Ruiyue Ping, Kaike Ping, Da Ye, Honggui Shen, Yili Chen, Yikai Li
OBJECTIVES: This study aimed to preliminarily explore the effects of the soft tissue mobilization of pushing on Qiao-Gong (MPQ) on biomechanical properties of the carotid artery using an animal model of carotid atherosclerosis (CAS). METHODS: Fifty rabbits were randomly divided into 4 groups: animals with CAS treated with MPQ (CAS-MPQ [n = 15]); animals with CAS treated without MPQ (CAS [n = 15]); normal animals treated with MPQ (normal-MPQ [n = 10]); and a blank control group (n = 10)...
February 2018: Journal of Manipulative and Physiological Therapeutics
Yue Yuan, Qin Zhang, Yun Yan, Miaomiao Gong, Qi Zhao, Zhihong Bao, Kaerdun Liu, Siling Wang
We report a simple strategy to prepare Tween 60@2β-CD self-assembly vesicles in aqueous solution as a new drug delivery carrier for cancer chemotherapy. The spherical shape of vesicles was confirmed by transmission electron microscopy (TEM) and mean particle sizes were about 33.7 nm, as measured by dynamic light scattering, micro-IR results indicated that the self-assembly vesicles was driven by hydrogen bonding. Hydrophilic doxorubicin (DOX) was successfully loaded into the self-assembly vesicles with drug loading content of 7...
November 2018: Drug Delivery
Mario Gotta, Christoph A Mayer, Jutta Huebner
BACKGROUND: The use of complementary and alternative medicine (CAM) for chronic diseases such as multiple sclerosis (MS) is becoming an increasingly important issue for those affected. Especially in Germany there are only a few studies dealing with CAM, as yet. The aim of this study was to assess the prevalence, the methods used, the subjective benefits as well as physician/patient communication. METHODS: A structured questionnaire including demographic and disease-specific data, CAM use, perceived benefits as well as physician/patient communication was sent to real and web-based self-help groups for MS in Germany...
February 2018: Complementary Therapies in Medicine
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