keyword
MENU ▼
Read by QxMD icon Read
search

1,25 hydroxyvitamin D

keyword
https://www.readbyqxmd.com/read/28822224/is-it-necessary-for-all-samples-to-quantify-25ohd2-and-25ohd3-using-lc-ms-ms-in-clinical-practice
#1
Songlin Yu, Ruiping Zhang, Weiyan Zhou, Xinqi Cheng, Qian Cheng, Liangyu Xia, Shaowei Xie, Yicong Yin, Dandan Sun, Wei Su, Ling Qiu
BACKGROUND: The demand for vitamin D testing is increasing in China. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) immunoassay is specific and accurate but requires expensive equipment, experienced operators, and complicated pretreatment of serum. Automated immunoassays are simple and convenient but only determine total 25-hydroxyvitamin D (25OHD). The objective of this study was to quantify 25OHD2 and 25OHD3 in patients to assist clinical physicians and laboratory directors in choosing the most appropriate method to determine 25OHD...
August 19, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28808890/vitamin-d-activity-and-metabolism-in-bone
#2
REVIEW
Paul H Anderson
PURPOSE OF REVIEW: In addition to the actions of the endocrine hormone, 1alpha,25-dihydroxyvitamin D (1,25(OH)2D) in stimulating intestinal calcium absorption, the regulation of bone mineral metabolism by 1,25(OH)2D is also considered an important contributor to calcium homeostasis. However, recent evidence suggest that 1,25(OH)2D acting either via endocrine or autocrine pathways plays varied roles in bone, which suggests that vitamin D contributes to the maintenance of bone mineral in addition to its catabolic roles...
August 14, 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/28806419/effects-of-short-term-dry-immersion-on-bone-remodeling-markers-insulin-and-adipokines
#3
Marie-Thérèse Linossier, Liubov E Amirova, Mireille Thomas, Myriam Normand, Marie-Pierre Bareille, Guillemette Gauquelin-Koch, Arnaud Beck, Marie-Claude Costes-Salon, Christine Bonneau, Claude Gharib, Marc-Antoine Custaud, Laurence Vico
BACKGROUND: Dry immersion (DI), a ground-based model of microgravity previously used in Russia, has been recently implemented in France. The aim of this study was to analyze early events in a short-term DI model in which all conditions are met to investigate who is first challenged from osteo- or adipo-kines and to what extent they are associated to insulin-regulating hormones. METHODS: Twelve healthy men were submitted to a 3-day DI. Fasting blood was collected during pre-immersion phase for the determination of the baseline data collection (BDC), daily during DI (DI24h, DI48H and DI72h), then after recovery (R+3h and R+24h)...
2017: PloS One
https://www.readbyqxmd.com/read/28804921/serum-thymidine-kinase-1-canine-c-reactive-protein-haptoglobin-and-vitamin-d-concentrations-in-dogs-with-immune-mediated-hemolytic-anemia-thrombocytopenia-and-polyarthropathy
#4
M Grobman, H Outi, H Rindt, C Reinero
BACKGROUND: Relapses of immune-mediated hemolytic anemia (IMHA), thrombocytopenia (ITP), or polyarthropathy (IMPA) occur despite normal hematologic and cytologic parameters. Thymidine kinase 1 (TK1), canine C-reactive protein (c-CRP), haptoglobin (HPT), and 25-Hydroxyvitamin-D (25(OH)D) might be adjunct to current monitoring strategies. HYPOTHESIS/OBJECTIVES: Compare serum concentrations of TK1, c-CRP, HPT, and 25(OH)D in dogs with well- and poorly controlled primary IMHA, ITP, or IMPA...
August 14, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28803880/vitamin-d-and-symptoms-of-depression-in-overweight-or-obese-adults-a-cross-sectional-study-and-randomized-placebo-controlled-trial
#5
Aya Mousa, Negar Naderpoor, Maximilian P J de Courten, Barbora de Courten
Recent evidence suggests that vitamin D deficiency may contribute to increased risk of depression. However, previous studies are limited by variability in participant characteristics including vitamin D deficiency status and presence of existing diseases, use of low doses of vitamin D supplementation for short durations, and use of co-interventions or psychotropic drugs. We examined whether 25-hydroxyvitamin D (25(OH)D) concentrations were associated with symptoms of depression, as well as whether vitamin D supplementation reduced symptoms of depression in overweight or obese and vitamin D-deficient, but otherwise healthy adults...
August 10, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28799838/vitamin-d-receptor-gene-foki-polymorphism-in-egyptian-children-and-adolescents-with-sle-a-case-control-study
#6
A A Imam, H E Ibrahim, M A A Farghaly, U M Alkholy, H H Gawish, N Abdalmonem, A M Sherif, Y F Ali, M E Hamed, N M Waked, M M Fathy, A M Khalil, M A Noah, M S Hegab, B R Ibrahim, R M Nabil, L A Fattah
Background Childhood-onset systemic lupus erythematosus (cSLE) is a lifelong autoimmune disorder. The vitamin D receptor (VDR) gene is a potential candidate gene for cSLE susceptibility. In this study, we aimed to investigate the FokI polymorphism in the VDR gene in Egyptian children and adolescents with SLE, to determine whether this polymorphism could be a genetic marker for cSLE susceptibility or disease activity and we also measured the serum level of 25-hydroxyvitamin D [25(OH) D] to assess its relation to such polymorphism...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28795765/vitamin-d-predictors-in-polycystic-ovary-syndrome-a-meta-analysis
#7
Flora Bacopoulou, Evangelia Kolias, Vasiliki Efthymiou, Constantine N Antonopoulos, Evangelia Charmandari
BACKGROUND: The aim of this meta-analysis was to examine differences and predictors of serum 25-hydroxyvitamin D concentrations in women with polycystic ovary syndrome (PCOS) compared with non-PCOS controls matched for body mass index. MATERIALS AND METHODS: Three databases were searched (2003-2015) to retrieve studies that evaluated serum 25-hydroxyvitamin D in PCOS women and controls. Meta-regression analysis was performed with anthropometric and metabolic/endocrine parameters as covariates...
August 10, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28795340/vertebral-fractures-assessed-with-dual-energy-x-ray-absorptiometry-in-patients-with-addison-s-disease-on-glucocorticoid-and-mineralocorticoid-replacement-therapy
#8
Valentina Camozzi, Corrado Betterle, Anna Chiara Frigo, Veronica Zaccariotto, Martina Zaninotto, Erica De Caneva, Paola Lucato, Walter Gomiero, Silvia Garelli, Chiara Sabbadin, Monica Salvà, Miriam Dalla Costa, Marco Boscaro, Giovanni Luisetto
PURPOSE: to assess bone damage and metabolic abnormalities in patients with Addison's disease given replacement doses of glucocorticoids and mineralocorticoids. METHODS: A total of 87 patients and 81 age-matched and sex-matched healthy controls were studied. The following parameters were measured: urinary cortisol, serum calcium, phosphorus, creatinine, 24-h urinary calcium excretion, bone alkaline phosphatase, parathyroid hormone, serum CrossLaps, 25 hydroxyvitamin D, and 1,25 dihydroxyvitamin D...
August 9, 2017: Endocrine
https://www.readbyqxmd.com/read/28794553/vitamin-d-level-in-alopecia-areata
#9
Yasmeen Jabeen Bhat, Insha Latif, Rauf Malik, Iffat Hassan, Gousia Sheikh, Kouser Sideeq Lone, Sabiya Majeed, Peerzada Sajad
BACKGROUND: Alopecia areata (AA) is an immune-mediated disease in which autoantigens play an important part in activating T-lymphocytes. Vitamin D has been associated with various autoimmune diseases, and Vitamin D receptors are strongly expressed in hair follicles and their expression in keratinocytes is necessary for the maintenance of the normal hair cycle. AIM: The aim of this study was to find the association between Vitamin D level and AA. MATERIALS AND METHODS: This was a hospital-based cross-sectional study in which 50 patients with clinically and trichoscopically diagnosed AA cases, and 35 healthy age- and sex-matched controls were studied in summer months...
July 2017: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/28791667/prevalence-of-vitamin-d-deficiency-in-girls-with-idiopathic-central-precocious-puberty
#10
Yue Zhao, Wenjun Long, Caiqi Du, Huanhuan Yang, Shimin Wu, Qin Ning, Xiaoping Luo
The relationship between vitamin D deficiency and idiopathic central precocious puberty (ICPP) has been recently documented. In this study, 280 girls diagnosed with ICPP and 188 normal puberty control girls of similar ages were enrolled and retrospectively studied. The ICPP group had significantly lower serum 25-hydroxyvitamin D (25[OH]D) levels than the control group. Furthermore, a nonlinear relationship was found between serum 25[OH]D and ICPP, and a cut-off point for serum 25[OH]D was found at 31.8 ng/ml for ICPP with and without adjusting the different confounding factors...
August 8, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/28791297/vitamin-d-uptake-in-patients-treated-with-a-high-dosed-purified-omega-3-compound-in-a-randomized-clinical-trial-following-an-acute-myocardial-infarction
#11
Patrycja A Naesgaard, Heidi Grundt, Arne F Nordøy, Harry Staines, Dennis W T Nilsen
BACKGROUND: Fish is the natural dietary source of vitamin D. Reports on the influence of purified omega-3 fatty acids on its uptake are scarce. OBJECTIVES: We investigated the impact of a purified high-dose omega-3 compound compared to corn oil on 25-hydroxyvitamin D [25(OH)D] levels following an acute myocardial infarction. METHODS: 228 patients were randomized 1:1 to receive a daily dose of either 4 g omega-3 (OMACOR(®)) or an equal dose of corn oil, administered double-blindly for 12 months...
2017: Frontiers in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28789713/vitamin-d-supplementation-and-vitamin-d-status-in-children-of-immigrant-background-in-norway
#12
Ahmed A Madar, Thomas E Gundersen, Anne M Haug, Haakon E Meyer
OBJECTIVE: Sufficient vitamin D status during infancy is important for child health and development. Several initiatives for improving vitamin D status among immigrant children have been implemented in Norway. The present study aimed to evaluate the vitamin D status and its determinants in children of immigrant background in Oslo. DESIGN: Cross-sectional study. SETTING: Child health clinics in Oslo. SUBJECTS: Healthy children with immigrant background (n 102) aged 9-16 months were recruited at the routine one-year check-up from two child health clinics with high proportions of immigrant clients...
August 9, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28780891/vitamin-d-and-corticotropin-releasing-hormone-in-term-and-preterm-birth-potential-contributions-to-preterm-labor-and-birth-outcome
#13
Sara A Mohamed, Abdeljabar El Andaloussi, Ayman Al-Hendy, Ramkumar Menon, Faranak Behnia, Jay Schulkin, Michael L Power
BACKGROUND: Poor maternal vitamin D status and elevated circulating corticotropin-releasing hormone (CRH) are associated with preterm birth. It is not known if these risk factors are independent or interrelated. Both are associated with inflammation. METHODS: We measured maternal circulating 25-hydroxyvitamin D (25-OH-D) and CRH from 97 samples collected from 15 early-preterm, 31 late-preterm, 21 early-term, and 30 term births. The potential involvement of vitamin D in the regulation of inflammation was evaluated by Q-PCR in human uterine smooth muscle (UTSM) cell line...
August 7, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28779988/impact-of-polymorphism-rs7041-and-rs4588-of-vitamin-d-binding-protein-on-the-extent-of-coronary-artery-disease
#14
V Daffara, M Verdoia, R Rolla, M Nardin, P Marino, G Bellomo, A Carriero, G De Luca
BACKGROUND AND AIM: 25-hydroxyvitamin D deficiency represents a widespread social problem but also an emerging risk factor for cardiovascular disease. Genetic variants of the Vitamin D Binding Protein (VDBP), the main transporter of vitamin D in the bloodstream, have been shown to account for a significant variability in the levels and systemic effects of vitamin D. We investigated whether the single nucleotide polymorphisms, rs7041 and rs4588, of VDBP are associated to the prevalence and extent of coronary artery disease...
June 24, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28776491/an-analysis-of-factors-associated-with-25-hydroxyvitamin-d-levels-in-white-and-non-white-canadians
#15
Stephen Brooks, Linda Greene-Finestone, Susan Whiting, Vitali Fioletov, Patrick Laffey, Nicholas Petronella
Vitamin D status was assessed in 19–79 year old whites (8351 participants of European ancestry) and non-whites (1840 participants encompassing all other ancestries) from cycles 1 to 3 (years 2007–2013) of the Canadian Health Measures Survey. Status was assessed using the U.S. Institute of Medicine (IOM) 25-hydroxyvitamin D [25(OH)D] cut point values of 30 and 40 nmol/L. Overall, median 25(OH)D concentrations were significantly higher in whites [58.9 (28.6, 100.1) nmol/L; 5th and 95th percentile] compared with non-whites [43...
August 4, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28775375/the-relationship-between-maternal-25-hydroxyvitamin-d-status-in-pregnancy-and-childhood-adiposity-and-allergy-an-observational-study
#16
V T Boyle, E B Thorstensen, J M D Thompson, L M E McCowan, E A Mitchell, K M Godfrey, L Poston, C R Wall, R Murphy, W Cutfield, T Kenealy, L C Kenny, P N Baker
BACKGROUND: Vitamin D insufficiency (defined as <75 nmol/l) is widespread amongst pregnant women around the world and has been proposed to influence offspring outcomes in childhood and into adult life, including adiposity and allergy. Disorders including asthma and eczema are on the rise amongst children. Our aim was to investigate the relationship between maternal 25-hydroxyvitamin D status in pregnancy and offspring adiposity, asthma and eczema in childhood. SUBJECTS AND METHODS: Maternal 25-hydroxyvitamin D concentrations were analysed in serum samples collected at 15 weeks' gestation from 1710 participants of the prospective Screening for Pregnancy Endpoints (SCOPE) cohort study...
August 4, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28771378/pretransplant-vitamin-d-deficiency-is-associated-with-higher-relapse-rates-in-patients-allografted-for-myeloid-malignancies
#17
Aleksandar Radujkovic, Lambros Kordelas, Julia Krzykalla, Dietrich W Beelen, Axel Benner, Nicola Lehners, Katharina Schmidt, Peter Dreger, Thomas Luft
Purpose Vitamin D (VitD) deficiency is common in patients with hematologic malignancies undergoing allogeneic transplantation (alloSCT), but its prognostic relevance is unclear. Patients and Methods The impact of pretransplant VitD status on overall survival, relapse mortality, and nonrelapse mortality was investigated retrospectively in a cohort of 492 patients undergoing alloSCT at our center from 2002 to 2013. VitD deficiency was defined as a serum level of 25-hydroxyvitamin D3 < 20 ng/mL (equivalent to < 50 nM) before alloSCT and was assessed using accredited laboratory methods and a standard chemiluminescent immunoassay...
August 3, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28768705/effects-of-vitamin-d2-supplementation-on-vitamin-d3-metabolism-in-health-and-ckd
#18
Zona Batacchi, Cassianne Robinson-Cohen, Andrew N Hoofnagle, Tamara Isakova, Bryan Kestenbaum, Kevin J Martin, Myles S Wolf, Ian H de Boer
BACKGROUND AND OBJECTIVES: Vitamin D supplements are prescribed to correct low circulating concentrations of 25-hydroxyvitamin D. In CKD, vitamin D metabolism is complicated by decreased conversion of 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D by CYP27B1 and possibly decreased conversion of 25-hydroxyvitamin D to 24,25-dihydroxyvitamin D by CYP24A1. The aim of this study was to determine the effects of vitamin D2 supplementation on vitamin D metabolism in health and CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a treatment-only intervention study of 25 individuals with CKD (eGFR<60 ml/min per 1...
August 2, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28768407/the-big-vitamin-d-mistake
#19
Dimitrios T Papadimitriou
Since 2006, type 1 diabetes in Finland has plateaued and then decreased after the authorities' decision to fortify dietary milk products with cholecalciferol. The role of vitamin D in innate and adaptive immunity is critical. A statistical error in the estimation of the recommended dietary allowance (RDA) for vitamin D was recently discovered; in a correct analysis of the data used by the Institute of Medicine, it was found that 8895 IU/d was needed for 97.5% of individuals to achieve values ≥50 nmol/L. Another study confirmed that 6201 IU/d was needed to achieve 75 nmol/L and 9122 IU/d was needed to reach 100 nmol/L...
July 2017: Journal of Preventive Medicine and Public Health, Yebang Ŭihakhoe Chi
https://www.readbyqxmd.com/read/28767604/serum-25-hydroxyvitamin-d-might-be-an-independent-prognostic-factor-for-graves-disease-recurrence
#20
Hwa Young Ahn, Yun Jae Chung, Bo Youn Cho
Graves disease is the most common cause of thyrotoxicosis. Although medical intervention with antithyroid drugs (ATDs) is commonly the first choice of treatment in Korea, the remission rate associated with this approach is not satisfactory. During ATD therapy, low or undetectable serum levels of thyroid-stimulating hormone (TSH) receptor antibodies (TRAbs) have been reported to affect the incidence of Graves disease remission. This study evaluated the correlation between serum 25-hydroxyvitamin D levels and TRAb levels, as well as the effect of 25-hydroxyvitamin D on the recurrence of Graves disease...
August 2017: Medicine (Baltimore)
keyword
keyword
13888
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"