keyword
MENU ▼
Read by QxMD icon Read
search

1,25 hydroxyvitamin D

keyword
https://www.readbyqxmd.com/read/29691706/low-concentrations-of-25-hydroxyvitamin-d-and-long-term-prognosis-of-copd-a-prospective-cohort-study
#1
Gitte Færk, Yunus Çolak, Shoaib Afzal, Børge G Nordestgaard
Role and importance of vitamin D deficiency in long-term prognosis of chronic obstructive pulmonary disease (COPD) still remains undetermined. We tested the hypothesis that among individuals with COPD, those with low concentrations of 25-hydroxyvitamin D have a poorer prognosis compared to those with normal concentrations. We studied 35,153 individuals from the general population aged 20-100 years with 25-hydroxyvitamin D measurements and spirometry, the Copenhagen City Heart Study [median follow-up 21 years (range 13 days-36 years)] and the Copenhagen General Population Study [7...
April 24, 2018: European Journal of Epidemiology
https://www.readbyqxmd.com/read/29690937/concentration-of-25-hydroxyvitamin-d-from-neonatal-dried-blood-spots-and-the-relation-to-gestational-age-birth-weight-and-ponderal-index-the-d-tect-study
#2
Amélie Keller, Mina N Händel, Peder Frederiksen, Ramune Jacobsen, Arieh S Cohen, John J McGrath, Berit L Heitmann
Studies have suggested that vitamin D status at birth may be associated with a range of neonatal outcomes. The aim of this study was to assess the association between neonatal 25-hydroxyvitamin D3 (25(OH)D3) concentration and gestational age, birth weight, Ponderal Index and size for gestational age. Neonatal capillary blood stored as dried blood spots was used to assess 25(OH)D3 concentrations among 2686 subjects selected from a random population sub-sample of individuals, born in Denmark from 1 May 1981 to 31 December 2002...
April 25, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29685623/dysregulated-1-25-dihydroxyvitamin-d-levels-in-high-fat-diet-induced-obesity-can-be-restored-by-changing-to-a-lower-fat-diet-in-mice
#3
Young Sun Jung, Dayong Wu, Donald Smith, Simin Nikbin Meydani, Sung Nim Han
Altered regulation of vitamin D metabolites, 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D (1,25[OH]2 D), was observed in high-fat diet (HFD)-induced obesity. We hypothesized that these HFD-induced changes in vitamin D metabolism would be reversed by decreasing fat mass through dietary intervention. Four-week-old C57BL/6J mice were assigned to 1 of 3 experimental diet groups: (1) the LL group was fed a control diet for 31 weeks, (2) the HH group was fed an HFD for 31 weeks, and (3) the HL group was fed HFD for 15 weeks then switched to the control diet for the remaining 16 weeks...
March 20, 2018: Nutrition Research
https://www.readbyqxmd.com/read/29673407/hypercalcemia-as-a-rare-presentation-of-angioimmunoblastic-t-cell-lymphoma-a-case-report
#4
Sana Chams, Inaya Hajj Hussein, Skye El Sayegh, Nour Chams, Khalid Zakaria
BACKGROUND: Angioimmunoblastic T cell lymphoma is a rare malignancy, accounting for only 2% of all non-Hodgkin lymphomas, first described in the 1970s and subsequently accepted as a distinct entity in the current World Health Organization classification. Due to the paucity of this disease, there is still no identifiable etiology, no consistent risk factors, and the pathogenesis remains unclear. CASE PRESENTATION: An 83-year-old Caucasian man presented to an emergency department with palpitations and was found to have atrial fibrillation...
April 20, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29672719/title-hormonal-contraceptive-use-is-associated-with-higher-total-but-unaltered-free-25-hydroxyvitamin-d-serum-concentrations
#5
Stefan Pilz, Rima Obeid, Verena Schwetz, Christian Trummer, Marlene Pandis, Elisabeth Lerchbaum, Thomas R Pieber, Barbara Obermayer-Pietsch, Manfred Wilhelm, Andreas Hahn, Christiane Schön
Context: Hormonal contraceptive (HC) intake is associated with higher total 25-hydroxyvitamin D (25[OH]D) concentrations but the effect of HC on free 25(OH)D is unclear. Objective: We investigated whether free 25(OH)D concentrations differ according to use of HC. Design: This is a post-hoc analysis of a randomized open trial. Setting: This study was conducted from 13th January to 9th May 2016 at a clinical research organization in Esslingen, Germany...
April 16, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29672176/prevalence-and-risk-factors-for-vascular-calcification-in-chinese-patients-receiving-dialysis-baseline-results-from-a-prospective-cohort-study
#6
Zhi-Hong Liu, Xue-Qing Yu, Jun-Wei Yang, Ai-Li Jiang, Bi-Cheng Liu, Chang-Ying Xing, Ji-Zhuang Lou, Mei Wang, Hong Cheng, Jun Liu, Jun-Zhou Fu, Ai-Hua Zhang, Miao Zhang, Qiao-Ling Zhou, Chen Yu, Rong Wang, Li Wang, Yu-Qing Chen, Tian-Jun Guan, Ai Peng, Chen Nan, Chuan-Ming Hao, Xu-Yang Cheng
OBJECTIVE: With limited data available on calcification prevalence in chronic kidney disease (CKD) patients on dialysis, the China Dialysis Calcification Study (CDCS) determined the prevalence of vascular/valvular calcification (VC) and association of risk factors in Chinese patients with prevalent hemodialysis (HD) or peritoneal dialysis (PD). METHODS: CKD patients undergoing HD/PD for ≥6 months were enrolled. Prevalence data for calcification and medical history were documented at baseline...
April 19, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29671819/dose-response-relationship-between-serum-retinol-levels-and-survival-in-patients-with-colorectal-cancer-results-from-the-dachs-study
#7
Haifa Maalmi, Viola Walter, Lina Jansen, Robert W Owen, Alexis Ulrich, Ben Schöttker, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner
Current knowledge on the role of retinol in the prognosis of patients with colorectal cancer (CRC) is very limited. We investigated the association of serum retinol levels with survival outcomes in a large cohort of 2908 CRC patients from Germany. Retinol concentrations were determined in serum collected shortly after diagnosis by mass spectrometry. Associations between serum retinol levels and survival outcomes were assessed using multivariable Cox regression and dose-response analyses. The joint association of serum retinol and serum 25-hydroxyvitamin D₃ (25(OH)D₃) with survival outcomes was also examined...
April 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29670260/familial-clustering-of-vitamin-d-deficiency-via-shared-environment-the-korean-national-health-and-nutrition-examination-survey-2008-2012
#8
Namki Hong, Young Ki Lee, Yumie Rhee
BACKGROUND/OBJECTIVES: Familial correlation of serum 25-hydroxyvitamin D concentration (25(OH)D) was reported in twin- or parent-offspring studies. However, data on relative contribution of environmental factors on familial clustering of 25(OH)D in extended families are limited. SUBJECTS/METHODS: We performed cross-sectional study using data from the Korean National Health and Nutrition Examination Survey (KNHANES) 2008-2012. Familial correlations of 25(OH)D were estimated in 28,551 subjects from 10,882 families...
April 18, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29666170/serum-25-hydroxyvitamin-d-levels-throughout-pregnancy-a-longitudinal-study-in-healthy-and-preeclamptic-pregnant-women
#9
Yessica Agudelo-Zapata, Luis Miguel Maldonado-Acosta, Hector Fabio Sandoval-Alzate, Natalia Elvira Poveda, María Fernanda Garcés, Jonathan Alexander Cortés-Vásquez, Andrés Felipe Linares-Vaca, Carlos Alejandro Mancera-Rodríguez, Shahar Alexandra Perea-Ariza, Karen Yuliana Ramírez-Iriarte, Camilo Andrés Castro-Saldarriaga, Juan Manuel Arteaga-Diaz, Roberto Franco-Vega, Edith Angel-Muller, Arturo José Parada-Baños, Jorge Eduardo Caminos
BACKGROUND: Worldwide there is a high prevalence of 25-hydroxyvitamin D (25OHD) deficiency, and has been associated with adverse outcomes during pregnancy. OBJECTIVE: This is a nested, case-control study in a longitudinal cohort to compare the serum 25OHD levels and other biomarkers throughout pregnancy in a group of 20 preeclamptic women and 61 healthy pregnant women. An additional group of 29 healthy non-pregnant women were also studied during the two phases of the menstrual cycle...
April 17, 2018: Endocrine Connections
https://www.readbyqxmd.com/read/29662333/the-prevalence-of-hypovitaminosis-d-and-its-associated-risk-factors-among-women-of-reproductive-age-in-saudi-arabia-a-systematic-review-and-meta-analysis
#10
REVIEW
Riyadh A Alzaheb
Vitamin D deficiency is currently a worldwide epidemic. Middle Eastern countries, including Saudi Arabia, have high vitamin D deficiency prevalence, most prominently among women, despite their plentiful year-round sunshine. Previous research investigating vitamin D status among Saudi women of reproductive age (15-49 years) is scarce, and no study has used a nationally representative sample, so this review quantified overall hypovitaminosis D prevalence among women in Saudi Arabia and explored the associated risk factors...
2018: Clinical Medicine Insights. Women's Health
https://www.readbyqxmd.com/read/29661746/effects-of-oral-vitamin-d-3-supplementation-in-stage-3-chronic-kidney-disease-subjects-insulin-resistance-syndrome-and-hormonal-disturb-interactions
#11
Amina Tahar, Faiza Zerdoumi, Messaoud Saidani, Lakhdar Griene, Elhadj-Ahmed Koceir
The 1-25-hydroxyvitamine D (1-25OHD) or calcitriol deficiency in chronic kidney disease (CKD) patients was associated with increases vascular calcification risk, nephrons reduction, bone deficit and cardiovascular mortality by atherosclerosis. The objective of this study was to investigate the pleiotropic effects of 200.000 IU (D200 group) every 3 months versus 30.000 IU (D30 group) every month dose vitamin D supplementation in stage 3 CKD patients. A cohort of 132 adult subjects was randomized into 2 groups according to dose vitamin D supplementation in deficient subjects (25OHD <50 nmol/L or <20 ng/mL)...
April 16, 2018: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/29655559/associations-between-bone-and-energy-metabolism-in-cows-fed-diets-differing-in-level-of-dietary-cation-anion-difference-and-supplemented-with-cholecalciferol-or-calcidiol
#12
R M Rodney, N P Martinez, P Celi, E Block, P C Thomson, G Wijffels, D R Fraser, J E P Santos, I J Lean
Bone-derived hormones play an important role in metabolism. This study examined the hypothesis that interactions between bone and energy metabolism, particularly those involving osteocalcin, are present in dairy cattle and have feedback mechanisms over time. Associations between metabolites in blood were examined in 32 Holstein cows blocked by parity and milk yield and randomly allocated to diets containing either 0.27 mg/kg dry matter (DM) calcidiol or cholecalciferol for an anticipated intake of 3 mg/d (120,000 IU/d) at 11 kg of DM, and positive (+130 mEq/kg DM) or negative (-130 mEq/kg DM) dietary cation-anion difference (DCAD) from 252 d of gestation to calving...
April 11, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29653103/sterol-regulatory-element-binding-protein-1-trans-activates-25-hydroxy-vitamin-d-3-24-hydroxylase-gene-expression-in-renal-proximal-tubular-cells
#13
Tomohiro Kagawa, Mina Kozai, Masashi Masuda, Nagakatsu Harada, Otoki Nakahashi, Mari Tajiri, Ryouhei Yoshikawa, Mari Nakao, Yuichiro Takei, Masayuki Iwano, Eiji Takeda, Yutaka Taketani, Hironori Yamamoto
The physiological activity of the steroid derived hormone vitamin D is regulated by several enzymatic steps. Both 25-hydroxy vitamin D3 1α-hydroxylase (CYP27B1) and 25-hydroxyvitamin D3 24-hydroxylase (CYP24A1) modulate blood levels of 1,25-dihydroxyvitamin D3 , an activated form of vitamin D. We previously demonstrated that CYP27B1 expression was trans-activated by sterol regulatory element binding protein 1 (SREBP1), although whether SREBP1 also regulates CYP24A1 transcription was unclear. Here we investigated the ability of SREBP1 to affect CYP24A1 transcription...
April 10, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29652819/the-when-what-how-of-measuring-vitamin-d-metabolism-in-clinical-medicine
#14
REVIEW
Niek F Dirks, Mariëtte T Ackermans, Paul Lips, Renate T de Jongh, Marc G Vervloet, Robert de Jonge, Annemieke C Heijboer
We now have the ability to measure a number of different vitamin D metabolites with very accurate methods. The most abundant vitamin D metabolite, 25-hydroxyvitamin D, is currently the best marker for overall vitamin D status and is therefore most commonly measured in clinical medicine. The added value of measuring metabolites beyond 25-hydroxyvitamin D, like 1,25-, and 24,25-dihydroxyvitamin D is not broadly appreciated. Yet, in some more complicated cases, these metabolites may provide just the information needed for a legitimate diagnosis...
April 13, 2018: Nutrients
https://www.readbyqxmd.com/read/29652114/associations-between-vitamin-d-levels-and-polycystic-ovary-syndrome-pcos-phenotypes
#15
Erin M Davis, Jennifer D Peck, Karl R Hansen, Barbara R Neas, LaTasha B Craig
BACKGROUND: Studies comparing serum 25-hydroxyvitamin D concentrations in women with and without PCOS have produced inconsistent results. Additionally, no previous studies have evaluated associations between vitamin D and specific PCOS phenotypes. METHODS: This case-control study was conducted among women undergoing intrauterine insemination. Cases (n=137) were diagnosed with PCOS and then further classified into 3 diagnostic phenotypes based on combinations of the Rotterdam criteria [ovulatory dysfunction +polycystic ovaries (n=55); ovulatory dysfunction +androgen excess (n=15); and ovulatory dysfunction, +polycystic ovaries, +androgen excess (n=67)]...
April 12, 2018: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29649340/the-relationship-between-alkaline-phosphatase-and-bone-alkaline-phosphatase-activity-and-the-growth-hormone-insulin-like-growth-factor-1-axis-and-vitamin-d-status-in-children-with-growth-hormone-deficiency
#16
Ewelina Witkowska-Sędek, Anna Stelmaszczyk-Emmel, Anna Majcher, Urszula Demkow, Beata Pyrżak
The relationships between bone turnover, the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and vitamin D are complex, but still not fully explained. The GH/IGF-1 axis and vitamin D can mutually modulate each other's metabolism and influence the activation of cell proliferation, maturation, and mineralization as well as bone resorption. The aim of this study was to evaluate the reciprocal associations between bone formation markers [alkaline phosphatase (ALP), bone alkaline phosphatase (BALP)], the GH/IGF-1 axis and 25-hydroxyvitamin D [25(OH)D] in children with growth hormone deficiency at baseline and during recombinant human growth hormone (rhGH) therapy...
April 13, 2018: Acta Biochimica Polonica
https://www.readbyqxmd.com/read/29644951/vitamin-d-deficiency-and-insufficiency-among-us-adults-prevalence-predictors-and-clinical-implications
#17
Xuefeng Liu, Ana Baylin, Phillip D Levy
Vitamin D deficiency (VDD) and insufficiency (VDI) are increasing at a global level, and they are associated with increased risk of various diseases. However, little information is available on the prevalence and predictors of VDD and VDI in a representative population of US adults. Serum 25-hydroxyvitamin D (25(OH)D) measurements were collected from 26 010 adults aged ≥18 years from the National Health and Nutrition Examination Survey (NHANES) 2001-2010. Using thresholds recommended by the Endocrine Society, VDD was defined as 25(OH)D<50 nmol/l and VDI as 50≤25(OH)D<75 nmol/l...
April 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29628969/association-between-vitamin-d-and-urinary-tract-infection-in-children
#18
Abolfazl Mahyar, Parviz Ayazi, Sara Safari, Reza Dalirani, Amir Javadi, Shiva Esmaeily
Purpose: The present study aimed to determine the relationship between serum 25-hydroxyvitamin D (25(OH)D) level and Urinary tract infections (UTIs) in children. Methods: In this case-control study, 70 children with UTI (case group) were compared with 70 healthy children (control group) in terms of serum 25(OH)D levels. The children were between 1 month and 12 years of age. Serum 25(OH)D levels were measured using enzyme-linked immunosorbent assay (ELISA). The results were analyzed and compared between both groups...
March 2018: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29623823/low-25-hydroxyvitamin-d-levels-are-independently-associated-with-autoimmune-thyroiditis-in-a-cohort-of-apparently-healthy-overweight-and-obese-subjects
#19
Giovanni De Pergola, Vincenzo Triggiani, Nicola Bartolomeo, Vito Angelo Giagulli, Michele Anelli, Michele Masiello, Vittoria Candita, Dario De Bellis, Franco Silvestris
BACKGROUND: Low vitamin D levels have been associated with autoimmune disorders and, then, with the Hashimoto's autoimmune thyroiditis (AT), the most common autoimmune disease. Obesity is characterized by lower vitamin D levels and higher risk to develop autoimmune diseases. The aim of the study was to examine the possibility of an association between AT and decreased 25(OH) vitamin D (25(OH)D) levels in a cohort of otherwise healthy overweight and obese subjects. MATERIALS AND METHODS: Two hundred sixty one overweight subjects (mean age: 40...
April 6, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29623355/clinical-and-laboratory-features-of-patients-with-osteomalacia-initially-presenting-with-neurological-manifestations
#20
S W Kim, N Hong, Y Rhee, Y-C Choi, H Y Shin, S M Kim
Patients with osteomalacia often visit the neurology department with conditions mimicking other myopathies. We analyzed clinical features of osteomalacia patients who visited the neurology department. These patients frequently presented with hypocalcemia, hypovitaminosis D, and pain with less severe weakness. Osteomalacia should be considered when patients present with pain and weakness. INTRODUCTION: Osteomalacia is a disease of bone metabolism; however, some patients with osteomalacia initially visit the neurology department...
April 5, 2018: Osteoporosis International
keyword
keyword
13888
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"