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https://www.readbyqxmd.com/read/28914106/concomitant-diseases-and-their-effect-on-disease-prognosis-in-meniere-s-disease-diabetes-mellitus-identified-as-a-negative-prognostic-factor
#1
Teemu Pieskä, Jouko Kotimäki, Minna Männikkö, Martti Sorri, Elina Hietikko
OBJECTIVE: To study comorbidities and their effect on the disease progression in Meniere's disease (MD). METHODS: Retrospective study on 350 definite MD patients diagnosed according to AAO-HNS 1995 criteria using hospital records and postal questionnaire. RESULTS: The prevalence of migraine, hypothyroidism, allergies, coronary heart disease and autoimmune diseases was more common in MD patients than reported in the general population of Finland...
September 15, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28903936/aortic-valve-stenosis-alters-expression-of-regional-aortic-wall-shear-stress-new-insights-from-a-4-dimensional-flow-magnetic-resonance-imaging-study-of-571-subjects
#2
Pim van Ooij, Michael Markl, Jeremy D Collins, James C Carr, Cynthia Rigsby, Robert O Bonow, S Chris Malaisrie, Patrick M McCarthy, Paul W M Fedak, Alex J Barker
BACKGROUND: Wall shear stress (WSS) is a stimulus for vessel wall remodeling. Differences in ascending aorta (AAo) hemodynamics have been reported between bicuspid aortic valve (BAV) and tricuspid aortic valve patients with aortic dilatation, but the confounding impact of aortic valve stenosis (AS) is unknown. METHODS AND RESULTS: Five hundred seventy-one subjects underwent 4-dimensional flow magnetic resonance imaging in the thoracic aorta (210 right-left BAV cusp fusions, 60 right-noncoronary BAV cusp fusions, 245 tricuspid aortic valve patients with aortic dilatation, and 56 healthy controls)...
September 13, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28888903/appropriateness-and-total-knee-arthroplasty-an-examination-of-the-american-academy-of-orthopaedic-surgeons-appropriateness-rating-system
#3
Daniel L Riddle, Robert A Perera
OBJECTIVE: The American Academy of Orthopaedic Surgeons (AAOS) recently published appropriateness criteria for patients with knee osteoarthritis (OA) who are being considered for total knee arthroplasty (TKA). We evaluated the extent to which predictor variables used by the AAOS contribute to final classification, rated as "appropriate," "may be appropriate" or "rarely appropriate." METHODS: The RAND/UCLA Appropriateness method was used by AAOS to develop 864 clinical vignettes, each incorporating eight evidence-based variables associated with TKA outcome or need...
September 6, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28888721/tmem106b-and-apoe-polymorphisms-in-chmp2b-mediated-frontotemporal-dementia-ftd-3
#4
Nina Rostgaard, Peter Roos, Esben Budtz-Jørgensen, Peter Johannsen, Gunhild Waldemar, Anne Nørremølle, Suzanne G Lindquist, Susanne Gydesen, Jeremy M Brown, John Collinge, Adrian M Isaacs, Troels T Nielsen, Jørgen E Nielsen
Single-nucleotide polymorphisms in the TMEM106B gene have been identified as a risk factor in frontotemporal dementia (FTD). The major allele of SNP rs3173615 is a risk factor in sporadic FTD, whereas the minor allele seems protective in GRN- and C9orf72-mediated FTD. The role of apolipoprotein E (ApoE) in FTD is uncertain, though an established risk factor in Alzheimer's disease. In a unique Danish family, inherited FTD is caused by a mutation in the CHMP2B gene located on chromosome 3 (FTD-3). In this family, both risk factors TMEM106B and ApoE were analyzed and correlated to age at onset (AAO) and progression in terms of age at institutionalization (AAI) and age at death (AAD)...
July 11, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28879771/nanopore-based-electrochemiluminescence-for-detection-of-micrornas-via-duplex-specific-nuclease-assisted-target-recycling
#5
Xiao-Lei Huo, Hui Yang, Wei Zhao, Jing-Juan Xu, Hong-Yuan Chen
In this study, we proposed a nanopore-based electrochemiluminescence (ECL) sensor combined with duplex-specific nuclease (DSN)-assisted target recycling amplification to detect microRNAs. Because of the synergetic effect of electrostatic repulsion and volume exclusion of gold nanoparticle-labeled DNA capture (DNA-Au NPs) to the negatively charged luminol anion probe, the DNA-Au NP-modified anodized aluminum oxide (AAO) nanopore electrode exhibited high ECL decline in comparison with the bare AAO electrode. Upon the introduction of DSN and target microRNA, the specific DNA-RNA binding and enzyme cleaving could trigger the detachment of capture DNA from the membrane surface, resulting in uncapping of AAO and an increased ECL signal...
September 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28870179/the-quality-of-systematic-reviews-about-interventions-for-refractive-error-can-be-improved-a-review-of-systematic-reviews
#6
Evan Mayo-Wilson, Sueko Matsumura Ng, Roy S Chuck, Tianjing Li
BACKGROUND: Systematic reviews should inform American Academy of Ophthalmology (AAO) Preferred Practice Pattern® (PPP) guidelines. The quality of systematic reviews related to the forthcoming Preferred Practice Pattern® guideline (PPP) Refractive Errors & Refractive Surgery is unknown. We sought to identify reliable systematic reviews to assist the AAO Refractive Errors & Refractive Surgery PPP. METHODS: Systematic reviews were eligible if they evaluated the effectiveness or safety of interventions included in the 2012 PPP Refractive Errors & Refractive Surgery...
September 5, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28858183/poorer-fusion-outcomes-in-diabetic-cervical-spondylotic-myelopathy-patients-undergoing-single-level-anterior-cervical-discectomy-and-fusion-does-not-compromise-functional-outcomes-and-quality-of-life
#7
Ming Han Lincoln Liow, Merrill Lee, Graham Seow-Hng Goh, Li Tat John Chen, Wai-Mun Yue, Chang Ming Guo, Seang Beng Tan
STUDY DESIGN: Retrospective matched pair cohort study using prospectively collected registry data. OBJECTIVES: To determine if patients with DM have (1):poorer patient-reported outcomes and;(2):poorer fusion rates after undergoing a single-level ACDF for cervical myelopathy. SUMMARY OF BACKGROUND DATA: Anterior Cervical Discectomy and fusion (ACDF) remains the most common procedure in the treatment of cervical spondylotic myelopathy (CSM);however, there is a paucity of literature with regards to patient-reported outcome measures (PROMs), health-related quality-of-life (HRQOL) scores and fusion rates post-ACDF in diabetic patients with CSM...
August 29, 2017: Spine
https://www.readbyqxmd.com/read/28820347/association-between-eye-diagnosis-and-positive-syphilis-test-results-in-a-large-urban-sexually-transmitted-infection-primary-care-clinic-population
#8
Ann-Marie Lobo, Yan Gao, Laura Rusie, Magda Houlberg, Supriya D Mehta
In 2015, the Centers for Disease Control and Prevention (CDC) and the American Academy of Ophthalmology (AAO) released clinical advisories on rising cases of ocular syphilis. We examined the association between eye disease and syphilis infection among primary care and sexually transmitted infection (STI) clinic patients attending an urban lesbian, gay, bisexual, transgender (LGBT) health center. We conducted a retrospective medical record review of all patients who underwent syphilis testing at Howard Brown Health between 1 January 2010 and 31 December 2015...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28805651/electrodeposition-of-vertically-standing-ag-nanoplates-and-nanowires-on-transparent-conductive-electrode-using-porous-anodic-aluminum-oxide-template
#9
Jue Wang, Shanlin Pan
We report fabricating vertically standing Ag nanoplates and nanowires on a transparent conductive substrate of indium tin oxides (ITO) with the assistance of a porous anodic aluminum oxide (AAO) template. Two-dimensional Ag nanoplates can be electrodeposited onto an AAO covered ITO surface without using an adhesion layer. Ag nanoplates obtained using AAO templates have 3 × {222} superlattice fringes, different from the 3 × {422} superlattice fringes reported in the previous study. Ag nanowires can be electrodeposited onto ITO which is initially covered with an AAO template through a conductive polymer poly (3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS)...
August 14, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28783302/monolayer-growth-front-of-precious-metals-through-insulating-mesoporous-membranes
#10
Nicholas Linck, Alex Peek, Bruce J Hinds
Monolayers of precious metals are deposited within the pores of insulating mesoporous anodized aluminum oxide (AAO) membranes via a new electrochemical underpotential Cu deposition growth front mechanism, followed by spontaneous galvanic replacement of copper by platinum or iridium as demonstrated by XPS, ICP-OES, conductivity, and current analysis. Applications include fuel cells, hydrogen storage, flow batteries, and electrocatalytic conversions.
September 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28772655/fabrication-of-polymeric-antireflection-film-manufactured-by-anodic-aluminum-oxide-template-on-dye-sensitized-solar-cells
#11
Jenn-Kai Tsai, Yu-Shin Tu
In this study, high energy conversion efficient dye-sensitized solar cells (DSSCs) were successfully fabricated by attaching a double anti-reflection (AR) layer, which is composed of a subwavelength moth-eye structured polymethyl methacrylate (PMMA) film and a polydimethylsiloxane (PDMS) film. An efficiency of up to 6.79% was achieved. The moth-eye structured PMMA film was fabricated by using an anodic aluminum oxide (AAO) template which is simple, low-cost and scalable. The nano-pattern of the AAO template was precisely reproduced onto the PMMA film...
March 15, 2017: Materials
https://www.readbyqxmd.com/read/28770931/high-performance-asymmetric-v2o5-sno2-nanopore-battery-by-atomic-layer-deposition
#12
Chanyuan Liu, Nam Kim, Gary W Rubloff, Sang Bok Lee
Here we report the high performance and cyclability of an asymmetric full cell nanopore battery, comprised of V2O5 as the cathode and prelithiated SnO2 as the anode, with integrated nanotubular Pt current collectors underneath each nanotubular storage electrode, confined within an anodized aluminium oxide (AAO) nanopore. Enabled by atomic layer deposition (ALD), this coaxial nanotube full cell is fully confined within a high aspect ratio nanopore (150 nm in diameter, 50 μm in length), with an ultra-small volume of about 1 fL...
August 3, 2017: Nanoscale
https://www.readbyqxmd.com/read/28770282/-diagnostic-criteria-for-meni%C3%A3-re-s-disease-according-to-the-classification-committee-of-the-b%C3%A3-r%C3%A3-ny-society
#13
REVIEW
J A Lopez-Escamez, J Carey, W-H Chung, J A Goebel, M Magnusson, M Mandalà, D E Newman-Toker, M Strupp, M Suzuki, F Trabalzini, A Bisdorff
This paper presents diagnostic criteria for Menière's disease jointly formulated by the Classification Committee of the Bárány Society, The Japan Society for Equilibrium Research, the European Academy of Otology and Neurotology (EAONO), the Equilibrium Committee of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) and the Korean Balance Society. The classification includes two categories: definite Menière's disease and probable Menière's disease. The diagnosis of definite Menière's disease is based on clinical criteria and requires the observation of an episodic vertigo syndrome associated with low- to medium-frequency sensorineural hearing loss and fluctuating aural symptoms (hearing, tinnitus and/or fullness) in the affected ear...
August 2, 2017: HNO
https://www.readbyqxmd.com/read/28760618/control-of-vertigo-in-m%C3%A3-ni%C3%A3-re-s-disease-by-intratympanic-dexamethasone
#14
A Weckel, M Marx, M-J Esteve-Fraysse
OBJECTIVE: The main objective was to assess the efficacy of intratympanic dexamethasone injection in controlling vertigo in unilateral Ménière's disease refractory to medical treatment. MATERIALS AND METHODS: A retrospective study included 25 patients with disabling unilateral Ménière's disease, defined according to the American Academy of Otorhinolaryngology-Head and Neck Surgery (AAO-HNS) criteria. Patients received intratympanic dexamethasone during the monitoring period...
July 28, 2017: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/28745487/self-climbed-amorphous-carbon-nanotubes-filled-with-transition-metal-oxide-nanoparticles-for-large-rate-and-long-lifespan-anode-materials-in-lithium-ion-batteries
#15
Shuoyu Li, Yuyi Liu, Peisheng Guo, Chengxin Wang
A composed material of amorphous carbon nanotubes (ACNTs) and encapsulated transition metal oxide (TMOs) nanoparticles was prepared by a common thermophysics effect, which is named the Marangoni effect, and a simple anneal process. The prepared ropy solution would form a Marangoni convection and climb into the channel of anodic aluminum oxide template (AAO) spontaneously. The ingenious design of the preparation method determined a distinctive structure of TMOs nanoparticles with a size of ∼5 nm and amorphous carbon coated outside full in the ACNTs...
August 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28744025/genetic-loci-associated-with-an-earlier-age-at-onset-in-multiplex-schizophrenia
#16
Annemarie L Woolston, Po-Chang Hsiao, Po-Hsiu Kuo, Shi-Heng Wang, Yin-Ju Lien, Chih-Min Liu, Hai-Gwo Hwu, Tzu-Pin Lu, Eric Y Chuang, Li-Ching Chang, Chien-Hsiun Chen, Jer-Yuarn Wu, Ming T Tsuang, Wei J Chen
An earlier age at onset (AAO) has been associated with greater genetic loadings in schizophrenia. This study aimed to identify modifier loci associated with an earlier AAO of schizophrenia. A genome-wide association analysis (GWAS) was conducted in 94 schizophrenia probands with the earliest AAO and 91 with the latest AAO. Candidate single nucleotide polymorphisms (SNPs) were then genotyped in the co-affected siblings and unrelated probands. Multi-SNP genetic risk scores (GRS) composed of the candidate loci were used to distinguish patients with an early or late AAO...
July 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28741408/appropriateness-of-tympanostomy-tubes-in-the-boston-metropolitan-area-are-the-aao-hnsf-guidelines-being-met
#17
Amy L Hughes, David Roberson, Cassandra Bannos, Emily K Trudell, Louis Vernacchio
Introduction Otitis media (OM) is the most common reason children receive general anesthesia, with bilateral tympanostomy tube (TT) insertion the second most common surgery in children. Prior research suggests overuse of TT. As part of a project designed to improve appropriateness of OM referrals, we evaluated appropriateness of TT insertion in a patient cohort. Methods Patients younger than 9 years with initial otolaryngology (ORL) visits in academic and private office settings for OM from January 1, 2012, to August 31, 2013, were identified through claims database...
July 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28738504/prevention-of-melanin-formation-during-aryl-alcohol-oxidase-production-under-growth-limited-conditions-using-an-aspergillus-nidulans-cell-factory
#18
Oscar Pardo-Planas, Rolf A Prade, Michael Müller, Hasan K Atiyeh, Mark R Wilkins
An Aspergillus nidulans cell factory was genetically engineered to produce an aryl alcohol oxidase (AAO). The cell factory initiated production of melanin when growth-limited conditions were established using stationary plates and shaken flasks. This phenomenon was more pronounced when the strain was cultured in a trickle bed reactor (TBR). This study investigated different approaches to reduce melanin formation in fungal mycelia and liquid medium in order to increase the enzyme production yield. Removal of copper from the medium recipe reduced melanin formation in agar cultures and increased enzyme activities by 48% in agitated liquid cultures...
July 8, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28737666/the-role-of-aopp-in-age-related-bone-loss-and-the-potential-benefits-of-berry-anthocyanins
#19
REVIEW
Melissa M Melough, Xin Sun, Ock K Chun
Age-related bone loss is a major factor in osteoporosis and osteoporotic fractures among the elderly. Because bone homeostasis involves a balance between bone formation and resorption, multiple mechanisms may induce age-dependent changes in bone. Oxidative stress is one such factor that contributes to the pathology of aging-associated osteoporosis (AAO). Advanced oxidation protein products (AOPP) are a biomarker of oxidant-mediated protein damage, and can also act to increase the production of reactive oxygen species (ROS), thereby perpetuating oxidative damage...
July 22, 2017: Nutrients
https://www.readbyqxmd.com/read/28733647/boiling-and-quenching-heat-transfer-advancement-by-nanoscale-surface-modification
#20
Hong Hu, Cheng Xu, Yang Zhao, Kirk J Ziegler, J N Chung
All power production, refrigeration, and advanced electronic systems depend on efficient heat transfer mechanisms for achieving high power density and best system efficiency. Breakthrough advancement in boiling and quenching phase-change heat transfer processes by nanoscale surface texturing can lead to higher energy transfer efficiencies, substantial energy savings, and global reduction in greenhouse gas emissions. This paper reports breakthrough advancements on both fronts of boiling and quenching. The critical heat flux (CHF) in boiling and the Leidenfrost point temperature (LPT) in quenching are the bottlenecks to the heat transfer advancements...
July 21, 2017: Scientific Reports
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