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Claire M Lawlor, Charles A Riley, John M Carter, Kimsey H Rodriguez
Importance: The 1996 Tonsillectomy and Adenoidectomy Inpatient Guidelines of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) Pediatric Otolaryngology Committee recommended that children younger than 3 years be admitted following tonsillectomy. Recommendations for hospital observation were not included as a key action statement in the 2011 AAO-HNS Clinical Practice Guidelines for Tonsillectomy in Children. Objective: To examine the association between posttonsillectomy complication rate and the age and weight of the child at the time of surgery...
March 15, 2018: JAMA Otolaryngology—Head & Neck Surgery
Javier Viña-Gonzalez, Katarina Elbl, Xavier Ponte, Francisco Valero, Miguel Alcalde
Aryl-alcohol oxidase (AAO) plays a fundamental role in the fungal ligninolytic secretome, acting as a supplier of H2 O2 . Despite its highly selective mechanism of action, the presence of this flavooxidase in different biotechnological settings has hitherto been hampered by the lack of appropriate heterologous expression systems. We recently described the functional expression of the AAO from Pleurotus eryngii in Saccharomyces cerevisiae by fusing a chimeric signal peptide (preαproK) and applying structure-guided evolution...
March 13, 2018: Biotechnology and Bioengineering
Samuel G Antoine, Alexander C Small, James M McKiernan, Ojas Shah
INTRODUCTION: Surgical subspecialty societies release clinical practice guidelines (CPGs) to provide topic-specific recommendations to healthcare providers. We hypothesize that there may be significant differences in statement strength and evidence quality both within the American Urological Association (AUA) guidelines and compared to those published by the American Academy of Orthopedic Surgeons (AAOS) and American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS). MATERIALS AND METHODS: CPGs issued through 2017 were extracted from the AUAnet...
February 2018: Canadian Journal of Urology
Anita Jeyakumar, Rodolpho E Bégué, Yu Jiang, Brian J McKinnon
OBJECTIVE: Guidelines for vaccination of cochlear implant (CI) recipients have been promulgated and updated by the Center for Disease Control and Prevention (CDC) to mitigate bacterial meningitis risk. The objective of this study was to survey current CI specialists on: 1) knowledge of current CDC CI recipient immunization recommendations, and 2) impediments to implementation of those guidelines. METHODS: A survey to assess knowledge of the CI recipient vaccination guidelines was administered to the American Academy of Otolaryngology-Head and Neck surgery (AAO-HNS), the American Cochlear Implant Alliance (ACIA), and the American Neurotology Society (ANS)...
March 9, 2018: Laryngoscope
Nada Abdulaziz, Anjali R Shah, William J McCune
PURPOSE OF REVIEW: Antimalarial drugs including chloroquine, its less toxic quinolone-derivative hydroxychloroquine (HCQ), and quinacrine have become cornerstones in the treatment of autoimmune diseases including systemic lupus, rheumatoid arthritis, sarcoidosis, and Sjogren syndrome; cutaneous disorders, antiphospholipid syndrome, and have recently been employed at higher dioses in oncology. Benefits include anti-inflammatory effects, protection against thrombosis, and improved control of hyperglycemia and hyperlipidemia...
March 6, 2018: Current Opinion in Rheumatology
Dohyun Im, Daisuke Matsui, Takatoshi Arakawa, Kimiyasu Isobe, Yasuhisa Asano, Shinya Fushinobu
l-Amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813 (l-AAO/MOG) catalyzes both the oxidative deamination and oxidative decarboxylation of the α-group of l-Lys to produce a keto acid and amide, respectively. l-AAO/MOG exhibits limited specificity for l-amino acid substrates with a basic side chain. We previously determined its ligand-free crystal structure and identified a key residue for maintaining the dual activities. Here, we determined the structures of l-AAO/MOG complexed with l-Lys, l-ornithine, and l-Arg and revealed its substrate recognition...
March 2018: FEBS Open Bio
Oliver J Gagné, Andrea Veljkovic, Mark Glazebrook, Timothy R Daniels, Murray J Penner, Kevin J Wing, Alastair S E Younger
BACKGROUND: People who are affected by end-stage ankle arthritis are as disabled as those suffering from arthritis in other main articulations of the lower extremity. Once these patients become unable to perform their job duties, they leave the workforce and require financial aid from government agencies, which represents a considerable economic burden. Regardless of whether arthrodesis or arthroplasty is performed, we hypothesized that patients younger than 55 years at the time of surgery should be able to return to work within 2 years and require less social assistance...
March 1, 2018: Foot & Ankle International
Fu Zhao, Bo Wang, Zhijun Yang, Qiangyi Zhou, Peng Li, Xingchao Wang, Jing Zhang, Junting Zhang, Pinan Liu
Surgical treatment of vestibular schwannoma (VS) in patients with neurofibromatosis type 2 (NF2) along with functional preservation of cranial nerves is challenging. The aim of this study was to analyze the outcomes of hearing and facial nerve function in patients with NF2 who underwent large-size VS (> 2 cm) surgery. From 2006 to 2016, one hundred and forty NF2 patients were included with 149 large-size VS resections using retrosigmoid approach. Hearing function was classified according to the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) criteria...
February 28, 2018: Journal of Neuro-oncology
Sujana S Chandrasekhar
Women otolaryngologists face issues that interfere with their wellness on a regular basis. Over the course of my career-in positions of leadership in academic practice and at the Academy's Board of Governors and Women in Otolaryngology Section and as past president of the AAO-HNS/F-I have had experiences and observations that I feel can help move the needle forward on these very important conversations.
February 1, 2018: Otolaryngology—Head and Neck Surgery
Jason A Beyea, Emily Rosen, Trina Stephens, Paul Nguyen, Stephen F Hall
Objective Tympanostomy tube (TT) insertion is the most common ambulatory surgery performed on children. American Academy of Otolaryngology-Head and Neck Surgery Founda-tion (AAO-HNSF) Clinical Practice Guidelines (CPGs) recommend hearing testing for all pediatric TT candidates. The aim of this study was to assess audiometric testing in this population. Study Design Retrospective population-based cohort study. Setting All hospitals in the Canadian province of Ontario. Subjects and Methods All patients 12 years of age and younger who underwent at least 1 TT procedure between January 1993 and June 2016...
February 1, 2018: Otolaryngology—Head and Neck Surgery
Irene Isabel López-Torres, Pablo Sanz-Ruíz, Coral Sánchez-Pérez, Ricardo Andrade-Albarracín, Javier Vaquero
INTRODUCTION: Acetabular revision surgery poses a challenge due to the increased frequency of severe defects and poor quality of the remaining bone. We compare the clinical and radiological outcomes, complications, and survival of two systems commonly used in complex acetabular revisions (AAOS types II, III, and IV): trabecular metal system (TM) and Burch-Schneider antiprotrusion cages (BS). METHODS: Eighty-four patients underwent acetabular revision surgery with TM or BS in our centre between 2008 and 2014...
February 26, 2018: International Orthopaedics
Yu-Chin Chien, Huei Chu Weng
In magnetowetting, the material properties of liquid, surface morphology of solid, and applied external field are three major factors used to determine the wettability of a liquid droplet on a surface. For wetting measurements, an irregular or uneven surface could result in a significant experimental uncertainty. The periodic array with a hexagonal symmetry structure is an advantage of the anodic aluminum oxide (AAO) structure. This study presents the results of the wetting properties of magnetic nanofluid sessile droplets on surfaces of various AAO pore sizes under an applied external magnetic field...
February 20, 2018: Nanomaterials
Benzhou Gong, Yingmu Wang, Jiale Wang, Wei Huang, Jian Zhou, Qiang He
A modified anaerobic-anoxic-oxic (AAO) reactor embedding electrolysis was constructed for treatment of low carbon/nitrogen (C/N) wastewater. The effect of different current conditions on the performance of reactor was investigated in this study. When the current ranged from 0 mA to 200 mA, the removal efficiency of total nitrogen (TN) increased from 61.25% (0 mA) to 75.60% (200 mA), and that of total phosphorus (TP) increased from 72.24% (0 mA) to 93.93% (200 mA). In addition, the removal efficiencies of chemical oxygen demand (COD) and NH4 + -N were not affected...
February 7, 2018: Bioresource Technology
Xiao-Yi Lv, Jun-Wei Hou, Zhi-Xian Gao, Hong-Fei Liu
CdS nanowires arrays were successfully synthesized by a simple solvothermal process using AAO as templates. The phase structures, morphologies, and optical properties of the products were investigated by X-ray diffraction, scanning electron microscopy, high-resolution transmission electron microscopy, Raman spectroscopy, and photoluminescence spectroscopy. It was found that the nanowires were composed of hexagonal structure CdS nanoparticles and the average diameters is about 60-70 nm. A strong green emission with a maximum around 505 nm was observed from the synthesized CdS nanowires at room temperature, which was attributed to near-band-edge emission...
May 1, 2018: Journal of Nanoscience and Nanotechnology
Jiangxia Fan, Xinxin Zhu, Kunzhou Wang, Xiaoyuan Chen, Xinqing Wang, Minhao Yan, Yong Ren
We have fabricated highly ordered anodized aluminum oxide (AAO) membranes with different diameter through improved hard anodization (HA) at high temperature. This process can generate thick AAO membranes (30 μm) in a short anodizing time with high growth rate 20-60 μm h-1 which is much faster than that in traditional mild two-step anodization. We enlarged the AAO pore diameter by adjusting the voltage rise rate at the same time, which has a great influence on current density and temperature. The AAO pore diameter varies from 60-110 nm to 160-190 nm...
May 1, 2018: Journal of Nanoscience and Nanotechnology
Xiaoqing Du, Yumeng Yang, Chenxi Yi, Yu Chen, Chao Cai, Zhao Zhang
Ni NTs and CeO2-Ni nanotubes (NTs) have been prepared by galvanostatic electrodeposition in anodic aluminum oxide (AAO) Templates. Scanning electron microscope (SEM), high resolution transmission electron microscopy (HRTEM), energy dispersive X-ray spectroscopic (EDS) and X-ray Diffraction (XRD) are used to characterize the prepared NTs. The results showed that the preparation process of CeO2-Ni NTs was accompanied by the formation of many new phases CeNix (x = 1, 2, 3.5 or 5) and preferential orientation crystal face of Ni in CeO2-Ni NTs is 〈111〉, which is different from that Ni 〈200〉 in Ni NTs...
July 1, 2018: Journal of Nanoscience and Nanotechnology
Alfredo de la Escosura-Muñiz, Marisol Espinoza-Castañeda, Alejandro Chamorro-García, Carlos J Rodríguez-Hernández, Carmen de Torres, Arben Merkoçi
In this work, we propose for the first time the use of anodic aluminum oxide (AAO) nanoporous membranes for in situ monitoring of parathyroid hormone-like hormone (PTHLH) secretion in cultured human cells. The biosensing system is based on the nanochannels blockage upon immunocomplex formation, which is electrically monitored through the voltammetric oxidation of Prussian blue nanoparticles (PBNPs). Models evaluated include a neuroblastoma cell line (SK-N-AS) and immortalized keratinocytes (HaCaT) as a control of high PTHLH production...
February 3, 2018: Biosensors & Bioelectronics
P M Bennett, T Stevenson, I D Sargeant, A Mountain, J G Penn-Barwell
OBJECTIVES: The surgical challenge with severe hindfoot injuries is one of technical feasibility, and whether the limb can be salvaged. There is an additional question of whether these injuries should be managed with limb salvage, or whether patients would achieve a greater quality of life with a transtibial amputation. This study aims to measure functional outcomes in military patients sustaining hindfoot fractures, and identify injury features associated with poor function. METHODS: Follow-up was attempted in all United Kingdom military casualties sustaining hindfoot fractures...
February 2018: Bone & Joint Research
Noah M Raizman, Philip E Blazar
No abstract text is available yet for this article.
March 15, 2018: Journal of the American Academy of Orthopaedic Surgeons
Shan-Shan Wang, Wen-Jing Hong, Yu-Qi Zhang, Shu-Bao Chen, Guo-Ying Huang, Hong-Yan Zhang, Li-Jun Chen, Lan-Ping Wu, Rong Shen, Yi-Qing Liu, Jun-Xue Zhu
OBJECTIVE: Clinical decision making in children with heart disease relies on detailed measurements of cardiac structures using two-dimensional and M-mode echocardiography. However, no echocardiographic reference values are available for the Chinese children. We aimed to establish z-score regression equations for left heart structures in a population-based cohort of healthy Chinese Han children. METHOD: Echocardiography was performed in 545 children with a normal heart...
February 12, 2018: Journal of Clinical Ultrasound: JCU
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