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Masaru Nakagawa, Akifumi Nakaya, Yasuto Hoshikawa, Shunya Ito, Nobuya Hiroshiba, Takashi Kyotani
Ultraviolet (UV) nanoimprint lithography is a promising nanofabrication technology with cost efficiency and high throughput for sub-20 nm size semiconductor, data storage, and optical devices. To test formability of organic resist mask patterns, we investigated whether the type of polymerizable di(meth)acrylate monomer affected the fabrication of cured resin nanopillars by UV nanoimprinting using molds with pores of around 20 nm. We used carbon-coated, porous, anodic aluminum oxide (AAO) films prepared by electrochemical oxidation and thermal chemical vapor deposition as molds, because the pore diameter distribution in the range of 10-40 nm was suitable for combinatorial testing to investigate whether UV-curable resins comprising each monomer were filled into the mold recesses in UV nanoimprinting...
October 21, 2016: ACS Applied Materials & Interfaces
Claire Montlahuc, Emmanuel Curis, Sarah Flora Jonas, Frank Bellivier, Sylvie Chevret
Gaussian mixture analysis is frequently used to model the age-at-onset (AAO) in bipolar I disorder and identify homogeneous subsets of patients. This study aimed to examine whether, using admixture analysis of AAO, cross-sectional designs (which cause right truncation), unreliable diagnosis for individuals younger than 10 years old (which causes left truncation) and the selection criterion used for admixture analysis impact the number of identified subsets. A simulation study was performed. Different criteria - the likelihood ratio test (LRT), the Akaike information criterion (AIC), and the Bayesian information criterion (BIC) - were compared using no, left and/or right truncation simulated data...
October 21, 2016: International Journal of Methods in Psychiatric Research
Sarav S Shah, Alexander M Satin, James R Mullen, Sara Merwin, Mark Goldin, Nicholas A Sgaglione
BACKGROUND: Prior to 2012, the American Academy of Orthopaedic Surgeons (AAOS) and American College of Chest Physicians (ACCP) differed in their recommendations for postoperative pharmacologic venous thromboembolism prophylaxis (VTEP) after total joint arthroplasty. More specifically, aspirin (ASA) monotherapy was not endorsed by the ACCP as an acceptable prophylaxis. In 2012, the ACCP supported ASA monotherapy compared with no prophylaxis. Our aim was to investigate the impact of the convergence of ACCP and AAOS recommendations on surgeon prescribing patterns after knee arthroplasty (KA)...
October 20, 2016: Journal of Orthopaedic Surgery and Research
Bhaskar Dudem, Yeong Hwan Ko, Jung Woo Leem, Joo Ho Lim, Jae Su Yu
We report the hierarchical nano/micro architectured (HNMA)-polydimethylsiloxane (PDMS) film-based hybrid energy cells with multi-functionality to simultaneously harvest mechanical, solar, and wind energies. These films consist of nano/micro dual-scale architectures (i.e., nanonipples on inverted micro pyramidal arrays) on the PDMS surface. The HNMA-PDMS is replicable by a facile and cost-effective soft imprint lithography (SIL) using a nanoporous anodic alumina oxide (AAO) film formed on the micro-pyramidal (MP) structured silicon substrate...
October 19, 2016: ACS Applied Materials & Interfaces
Tao Zhang, Zehua Huang, Xiaohong Chen, Mingzhi Huang, Jujun Ruan
Dimethyl phthalate (DMP) as one of the most important and extensively used Phthalic acid esters (PAEs) is known to likely cause dysfunctions of the endocrine systems, liver, and nervous systems of animals. In this paper, the degradation and behavior of DMP were investigated in a laboratory scale anaerobic/anoxic/oxic (AAO) treatment system. In addition, a degradation model including biodegradation and sorption was formulated so as to evaluate the fate of DMP in the treatment system, and a mass balance model was designed to determine kinetic parameters of the removal model...
October 8, 2016: Journal of Environmental Management
Ming-Hsiang Cheng, Hao-Wen Ko, Pei-Yun Chung, Chun-Wei Chang, Jiun-Tai Chen
The microphase separation behavior of block copolymers confined in cylindrical nanopores has been extensively investigated. Recently, the solvent-annealing-induced nanowetting in templates (SAINT) method has been demonstrated to be a versatile approach for the infiltration of block copolymers into the nanopores of porous templates. The function of the annealing solvents, however, is still not well understood, especially in the morphology control of the fabricated block copolymer nanostructures. In this work, we elucidate the function of the annealing solvents in the SAINT method using a lamella-forming block copolymer, polystyrene-block-polydimethylsiloxane (PS-b-PDMS), and anodic aluminum oxide (AAO) templates...
October 4, 2016: Soft Matter
Magdalena Tarnacka, Anna Chrobok, Karolina Matuszek, Sylwia Golba, Paulina Maksym, Kamil Kaminski, Marian Paluch
Broadband Dielectric Spectroscopy (BDS) and Differential Scanning Calorimetry (DSC) have been employed to probe dynamics and charge transport of 1-butyl-3-vinylimidazolium bis(trifluoromethanesulfonyl)imide ([bvim][NTf2]) confined in native uniaxial AAO pores as well as to study kinetics of radical polymerization of the examined compound as a function of the degree of confinement. Subsequently, the electronic conductivity of the produced polymers was investigated. As observed, polymerization carried out at T = 363 K proceeds faster under confinement with some saturation effect observed for the sample in pores of smaller diameter...
October 6, 2016: ACS Applied Materials & Interfaces
Sang Min Kim, Dae Jin Kim, Sungho Park
We report three-dimensional helical Au nanostructures using anodized aluminum oxide (AAO) and the embedded Pd nanosprings, serving as primary and secondary templates, respectively. The resulting Au nanohelices exhibit strong SERS signals due to the electromagnetic field enhancement originating from the helical morphology; this behavior is seemingly analogous to that of a nano-gap enhancer. Nanospring electrochemical lithography (NEL) represents a new method for synthesizing complex helical nanostructures and has potential for application in materials science...
September 13, 2016: Chemical Communications: Chem Comm
Saravanan Esakki, Joy MacDermid, Saipriya Vajravelu
Background: American Academy of Orthopaedic Surgeons (AAOS) distal radius fracture (DRF) clinical practice guidelines (CPG) are readily available to clinicians, patients, and policymakers. International Classification of Functioning, Disability, and Health (ICF) provides a framework for describing the impact of health conditions. The International Classification of Diseases-10th Revision (ICD-10) is a classification system to classify health conditions as specific disease or disorders. The aim of this study is to analyze and describe the scope and focus of the AAOS DRF CPG using the ICF and ICD-10 as a basis for content analysis, and to compare the content of the CPG with the ICF hand core sets as the reference standard...
September 2016: Hand: Official Journal of the American Association for Hand Surgery
Ryan Charles, Brandon Hood, Joseph M Derosier, John W Gosbee, Ying Li, Michelle S Caird, J Sybil Biermann, Mark E Hake
Providing quality patient care is a basic tenant of medical and surgical practice. Multiple orthopaedic programs, including The Patient Safety Committee of the American Academy of Orthopaedic Surgeons (AAOS), have been implemented to measure quality of surgical care, as well as reduce the incidence of medical errors. Structured Root Cause Analysis (RCA) has become a recent area of interest and, if performed thoroughly, has been shown to reduce surgical errors across many subspecialties. There is a paucity of literature on how the process of a RCA can be effectively implemented...
2016: Patient Safety in Surgery
Kelly Jarvis, Marleen Vonder, Alex J Barker, Susanne Schnell, Michael Rose, James Carr, Joshua D Robinson, Michael Markl, Cynthia K Rigsby
BACKGROUND: Peak velocity measurements are used to evaluate the significance of stenosis in patients with transposition of the great arteries after the arterial switch operation (TGA after ASO). 4D flow cardiovascular magnetic resonance (CMR) provides 3-directional velocity encoding and full volumetric coverage of the great arteries and may thus improve the hemodynamic evaluation in these patients. The aim of this study was to compare peak velocities measured by 4D flow CMR with 2D phase contrast (PC) CMR and the gold standard Doppler echocardiography (echo) in patients with TGA after ASO...
2016: Journal of Cardiovascular Magnetic Resonance
Xin Sui, Zhen Zhang, Zhenyu Zhang, Zhiwei Wang, Chao Li, Hao Yuan, Longcheng Gao, Liping Wen, Xia Fan, Lijun Yang, Xinru Zhang, Lei Jiang
pH-gated ion channels in cell membranes play important roles in the cell's physiological activities. Many artificial nanochannels have been fabricated to mimic the natural phenomenon of pH-gated ion transport. However, these nanochannels show pH sensitivity only within certain pH ranges. Wide-range pH sensitivity has not yet been achieved. Herein, for the first time, we provide a versatile strategy to increase the pH-sensitive range by using dual amphoteric nanochannels. In particular, amphoteric polymeric nanochannels with carboxyl groups derived from a block copolymer (BCP) precursor and nanochannels with hydroxyl groups made from anodic alumina oxide (AAO) were used...
October 10, 2016: Angewandte Chemie
Axel Marx, Alexander Beier, Anne Richter, Christoph H Lohmann, Andreas M Halder
INTRODUCTION: Major bone defects are the greatest challenge in hip revision arthroplasty. METHODS: In a prospective, consecutive nonrandomised study we followed up 74 patients with Type III (AAOS) acetabular bone defects who underwent revision hip arthroplasty with bone grafting and implantation of a Burch-Schneider anti-protrusion cage (APC). The patients were examined pre- and postoperatively according to a standardised clinical and radiological protocol. No patient was lost to follow-up...
September 20, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
Isabel R F Guiamba, Ulf Svanberg
The impact of acidification with citric acid, addition of EDTA or water blanching at high temperature, and short time (HTST) conducted at 90°C for 4 min, on the retention of vitamin C (L-AA and DHAA) and β-carotene was studied in mango purée 30 min after crushing. HTST blanching prior to matrix disruption into purée resulted in complete inactivation of polyphenol oxidase (PPO) and minor residual activity (8%) of ascorbic acid oxidase (AAO). The retention of total vitamin C was 100% in blanched purées and in purée with EDTA and about 90% in purées at pH 3...
September 2016: Food Science & Nutrition
Heather Roberts, Dafang Zhang, George S M Dyer
BACKGROUND: The Internet has become a major resource for patients; however, patient education materials are frequently written at relatively high levels of reading ability. The purpose of this study was to evaluate the readability of patient education materials on the American Academy of Orthopaedic Surgeons (AAOS) web site. METHODS: Readability scores were calculated for all patient education articles on the AAOS web site using 5 algorithms: Flesch Reading Ease, Flesch-Kincaid Grade Level, SMOG (Simple Measure of Gobbledygook) Grade, Coleman-Liau Index, and Gunning-Fog Index...
September 7, 2016: Journal of Bone and Joint Surgery. American Volume
Z Zhang, Y Nguyen, D De Seta, F Y Russo, A Rey, M Kalamarides, O Sterkers, D Bernardeschi
The management of sporadic vestibular schwannoma (VS) has evolved in the last decades. The aim of this study was to analyse the evolution in surgical outcomes of VSs operated by a neurotological team between 1990 and 2006 by different approaches. A monocentric retrospective review of medical charts of 1006 patients was performed. In order to assess eventual changes and progress, the 17-years period was divided in three periods, each one comprehending 268 VS (1990-1996), 299 VS (1997-2001), and 439 VS (2002-2006)...
September 6, 2016: Acta Otorhinolaryngologica Italica
M Scheich, D Ehrmann-Müller, W Shehata-Dieler, R Hagen
OBJECTIVE: The aim of this study was to evaluate the hearing results after surgery for T1 and T2 vestibular schwannomas (VS) via the middle cranial fossa (MCF) approach at one institution and to review outcomes in the recent literature. PATIENTS AND METHODS: In our department, 208 consecutive patients have undergone surgery using the MCF approach between December 2005 and February 2015. Audiological testing included pure-tone audiometry, speech-discrimination-tests pre- and postoperatively, as well as a pre- and intraoperative brainstem evoked response audiometry (BERA)...
September 2, 2016: HNO
Spoorthi Thammaiah, Vinaya Manchaiah, Vijayalakshmi Easwar, Rajalakshmi Krishna
The objective of this study was to translate and adapt five English self-report health measures to a South Indian language Kannada. Currently, no systematically developed questionnaires assessing hearing rehabilitation outcomes are available for clinical or research use in Kannada. The questionnaires included for translation and adaptation were the hearing handicap questionnaire, the international outcome inventory - hearing aids, the self-assessment of communication, the participation scale, and the assessment of quality of life - 4 dimensions...
April 20, 2016: Audiology Research
Ke-Sheng Wang, Xuefeng Liu, Changchun Xie, Ying Liu, Chun Xu
Non-parametric methods such as Wilcoxon test have the advantages of no assumptions for the underlying survival distributions. Alzheimer's disease (AD) is a chronic neurodegenerative disease while the ectopic P-granules autophagy protein 5 homolog (EPG5 gene) is highly expressed in human brain and may implicate in the pathogenesis of neurodegenerative disorders. The present study explored the associations of 26 single-nucleotide polymorphisms (SNPs) in the EPG5 gene with the age at onset (AAO) of AD using a family-based association test (FBAT)-Wilcoxon statistic in a family-based study...
September 1, 2016: Journal of Molecular Neuroscience: MN
Charles Anthony Hughes, Patrick McMenamin, Vikas Mehta, Harold Pillsbury, David Kennedy
OBJECTIVES/HYPOTHESIS: The number of trained otolaryngologists available is insufficient to supply current and projected US health care needs. The goal of this study was to assess available databases and present accurate data on the current otolaryngology workforce, examine methods for prediction of future health care needs, and explore potential issues with forecasting methods and policy implementation based on these predictions. STUDY DESIGN: Retrospective analysis of research databases, public use files, and claims data...
August 31, 2016: Laryngoscope
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