keyword
MENU ▼
Read by QxMD icon Read
search

ROLLAND

keyword
https://www.readbyqxmd.com/read/28072848/physiologic-determinants-of-exercise-capacity-in-pulmonary-langerhans-cell-histiocytosis-a-multidimensional-analysis
#1
Camille Rolland-Debord, Stephanie Fry, Jonathan Giovannelli, Carole Langlois, Nicolas Bricout, Bernard Aguilaniu, Agnes Bellocq, Olivier Le Rouzic, Stephane Dominique, Alain Delobbe, Geraldine François, Abdellatif Tazi, Benoit Wallaert, Cecile Chenivesse
BACKGROUND: Reduced exercise capacity severely impacts quality of life in pulmonary Langerhans cell histiocytosis. Ascertaining mechanisms that impair exercise capacity is necessary to identify targets for symptomatic treatments. METHODS: Dyspnea, pulmonary function tests and cardiopulmonary exercise test were analysed in 62 study participants. Data were compared between subjects with impaired and normal aerobic capacity (V'O2 peak less than 84% versus 84% predicted or more)...
2017: PloS One
https://www.readbyqxmd.com/read/28069933/no-correlation-between-mtdna-amount-and-methylation-levels-at-the-cpg-island-of-polg-exon-2-in-wild-type-and-mutant-human-differentiated-cells
#2
Julie Steffann, Aurore Pouliet, Houda Adjal, Christine Bole, Cécile Fourrage, Jelena Martinovic, Louise Rolland-Galmiche, Agnes Rotig, Frédéric Tores, Arnold Munnich, Jean-Paul Bonnefont
BACKGROUND: While mitochondrial DNA (mtDNA) copy number is strictly regulated during differentiation and according to cell type, very little is known regarding the mechanism which accurately controls mtDNA copy number in human. Exon 2 of the human POLG gene, encoding the catalytic subunit of the mitochondrial-specific DNA polymerase gamma, contains a CpG island, highly conserved in mice and human. Changes of DNA methylation at the POLG locus have been shown to modulate mtDNA copy number during cell differentiation in both mouse and human...
January 9, 2017: Journal of Medical Genetics
https://www.readbyqxmd.com/read/28057817/contractile-efficiency-of-dystrophic-mdx-mouse-muscle-in-vivo-and-ex-vivo-assessment-of-adaptation-to-exercise-of-functional-end-points
#3
Roberta Francesca Capogrosso, Paola Mantuano, Anna Cozzoli, Francesca Sanarica, Ada Maria Massari, Elena Conte, Adriano Fonzino, Arcangela Giustino, Jean-Francois Rolland, Angelo Quaranta, Michela De Bellis, Giulia Maria Camerino, Robert W Grange, Annamaria De Luca
Progressive weakness is a typical feature of Duchenne muscular dystrophy (DMD) patients and is exacerbated in the benign mdx mouse model by in vivo treadmill exercise. We hypothesized a different threshold for functional adaptation of mdx muscles in response to the duration of the exercise protocol. In vivo weakness was confirmed by grip strength after 4, 8 and 12 weeks of exercise in mdx mice. Torque measurements revealed that exercise-related weakness in mdx mice correlated with the duration of the protocol, while wild-type (wt) mice were stronger...
January 5, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28054340/fingolimod-confers-neuroprotection-through-activation-of-rac1-after-experimental-germinal-matrix-hemorrhage-in-rat-pups
#4
William B Rolland, Paul R Krafft, Tim Lekic, Damon Klebe, Julia LeGrand, Abby Jones Weldon, Liang Xu, John H Zhang
Fingolimod, a sphingosine-1-phosphate receptor (S1PR) agonist, is clinically available to treat multiple sclerosis and is showing promise in treating stroke. We investigated if fingolimod provides long-term protection from experimental neonatal germinal matrix hemorrhage (GMH), aiming to support a potential mechanism of acute fingolimod-induced protection. GMH was induced in P7 rats by infusion of collagenase (0.3 U) into the right ganglionic eminence. Animals euthanized at four weeks post-GMH received low or high dose fingolimod (0...
January 5, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28049102/prevalence-and-clinical-severity-of-mood-disorders-among-first-second-and-third-generation-migrants
#5
Baptiste Pignon, Geoffroy Pierre Alexis, Pierre Thomas, Jean-Luc Roelandt, Benjamin Rolland, Craig Morgan, Guillaume Vaiva, Ali Amad
BACKGROUND: The role of migration as a risk factor remains unknown for mood disorders because of poor data. We sought to examine the prevalence and severity of mood disorders (bipolar disorder (BD), unipolar depressive disorder (UDD) and dysthymia) in first, second, and third generation migrants in France. METHODS: The Mental Health in the General Population survey interviewed 38,694 individuals. The prevalence of lifetime mood disorders, comorbidities, and clinical features was compared between migrants and non-migrants and by generation...
December 27, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28040798/a-mem1-like-motif-directs-mesophyll-cell-specific-expression-of-the-gene-encoding-the-c4-carbonic-anhydrase-in-flaveria
#6
Udo Gowik, Stefanie Schulze, Montserrat Saladié, Vivien Rolland, Sandra K Tanz, Peter Westhoff, Martha Ludwig
The first two reactions of C4 photosynthesis are catalysed by carbonic anhydrase (CA) and phosphoenolpyruvate carboxylase (PEPC) in the leaf mesophyll (M) cell cytosol. Translatome experiments using a tagged ribosomal protein expressed under the control of M and bundle-sheath (BS) cell-specific promoters showed transcripts encoding CA3 from the C4 species Flaveria bidentis were highly enriched in polysomes from M cells relative to those of the BS. Localisation experiments employing a CA3-green fluorescent protein fusion protein showed F...
December 30, 2016: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28018378/molecular-identification-of-broomrape-species-from-a-single-seed-by-high-resolution-melting-analysis
#7
Mathieu Rolland, Aurélie Dupuy, Aude Pelleray, Philippe Delavault
Broomrapes are holoparasitic plants spreading through seeds. Each plant produces hundreds of thousands of seeds which remain viable in the soils for decades. To limit their spread, drastic measures are being taken and the contamination of a commercial seed lot by a single broomrape seed can lead to its rejection. Considering that broomrapes species identification from a single seed is extremely difficult even for trained botanists and that among all the described species, only a few are really noxious for the crops, numerous seed lots are rejected because of the contamination by seeds of non-noxious broomrape species...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28017447/association-between-cachexia-chemotherapy-and-outcomes-in-older-cancer-patients-a-systematic-review
#8
REVIEW
Philippe Caillet, Evelyne Liuu, Agathe Raynaud Simon, Marc Bonnefoy, Olivier Guerin, Gilles Berrut, Bruno Lesourd, Claude Jeandel, Monique Ferry, Yves Rolland, Elena Paillaud
BACKGROUND & AIMS: The aims of this systematic review were (i) to determine the prevalence of malnutrition and cachexia in older cancer patients in a chemotherapy setting, and (ii) to report the chemotherapy-related causes of malnutrition and (iii) the consequences of malnutrition on the outcomes of these patients. METHODS: We searched MEDLINE for articles published in English or French between 2005 and 2016 and which reported retrospective or prospective, observational or interventional studies of the prevalence of malnutrition and its consequences in patients 65 years or older with solid tumors and chemotherapy-related causes of malnutrition...
December 18, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28005133/formulation-of-generalised-mass-transfer-correlations-for-blood-oxygenator-design
#9
Kenny Wei Quan Low, Raoul van Loon, Sam Rolland, Johann Sienz
This paper numerically investigates non-Newtonian blood flow with oxygen and carbon dioxide transport across and along an array of uniformly square and staggered arranged fibres at various porosity (e) levels, focussing on a low Reynolds number regime (Re < 10). The objective is to establish suitable mass transfer correlations, expressed in the form of Sherwood number (Sh = f (e,Re,Sc)), that identifies the link from local mass transfer investigations to full-device analyses. The development of a concentration field is initially investigated and expressions are established covering the range from a typical deoxygenated condition up to a full oxygenated condition...
December 22, 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28003033/short-physical-performance-battery-and-all-cause-mortality-systematic-review-and-meta-analysis
#10
Rita Pavasini, Jack Guralnik, Justin C Brown, Mauro di Bari, Matteo Cesari, Francesco Landi, Bert Vaes, Delphine Legrand, Joe Verghese, Cuiling Wang, Sari Stenholm, Luigi Ferrucci, Jennifer C Lai, Anna Arnau Bartes, Joan Espaulella, Montserrat Ferrer, Jae-Young Lim, Kristine E Ensrud, Peggy Cawthon, Anna Turusheva, Elena Frolova, Yves Rolland, Valerie Lauwers, Andrea Corsonello, Gregory D Kirk, Roberto Ferrari, Stefano Volpato, Gianluca Campo
BACKGROUND: The Short Physical Performance Battery (SPPB) is a well-established tool to assess lower extremity physical performance status. Its predictive ability for all-cause mortality has been sparsely reported, but with conflicting results in different subsets of participants. The aim of this study was to perform a meta-analysis investigating the relationship between SPPB score and all-cause mortality. METHODS: Articles were searched in MEDLINE, the Cochrane Library, Google Scholar, and BioMed Central between July and September 2015 and updated in January 2016...
December 22, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27988884/proactive-regional-pharmacovigilance-system-versus-national-spontaneous-reporting-for-collecting-safety-data-on-concerning-off-label-prescribing-practices-an-example-with-baclofen-and-alcohol-dependence-in-france
#11
Marine Auffret, Julien Labreuche, Alain Duhamel, Sylvie Deheul, Olivier Cottencin, Régis Bordet, Sophie Gautier, Benjamin Rolland
INTRODUCTION: Off-label prescribing (OLP) may raise serious safety concerns that traditional spontaneous reporting of adverse drug reactions (ADRs) may not identify in a timely manner. In France, the 'Multidisciplinary Consultation Service for Off-Label Prescribing in Addiction Medicine' (CAMTEA) is a proactive regional system established to identify ADRs associated with the OLP of baclofen for alcohol dependence. OBJECTIVE: The aim was to demonstrate, using the French pharmacovigilance database (FPVD), that CAMTEA allowed for the reporting of a substantial amount of ADRs, comparable in nature to those provided via spontaneous reporting...
December 17, 2016: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/27988005/corrigendum-to-plant-crafted-starches-for-bioplastics-production-carbohydr-polym-152-2016-398-408
#12
Domenico Sagnelli, Kim H Hebelstrup, Eric Leroy, Agnès Rolland-Sabaté, Sophie Guilois, Jacob J K Kirkensgaard, Kell Mortensen, Denis Lourdin, Andreas Blennow
No abstract text is available yet for this article.
February 10, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27987812/effect-of-xyloglucan-molar-mass-on-its-assembly-onto-the-cellulose-surface-and-its-enzymatic-susceptibility
#13
Ana Villares, Hervé Bizot, Céline Moreau, Agnès Rolland-Sabaté, Bernard Cathala
Xyloglucan from tamarind seed has been submitted to an ultrasound treatment that reduces its molecular size to investigate the impact of molar mass on the interaction with cellulose. A low molar mass xyloglucan fraction (XGu, 1.04×10(5)gmol(-1)) was purified and its adsorption on the cellulose nanocrystal (CNC) surface has been investigated comparatively to the native fraction that presents high molar mass (XGn, 10.28×10(5)gmol(-1)). XGn arranged as loops and tails on CNCs whereas XGu formed trains onto the cellulose surface...
February 10, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27984918/phone-based-safety-monitoring-of-the-first-year-of-baclofen-treatment-for-alcohol-use-disorder-the-baclophone-cohort-study-protocol
#14
Benjamin Rolland, Marine Auffret, Julien Labreuche, Maryse Lapeyre-Mestre, Malek Dib, Aomar Kemkem, Isabelle Grit, Marie Drelon, Alain Duhamel, Nicolas Cabe, François Vabret, Olivier Guillin, Alexandre Baguet, Céline Masquelier, Alain Dervaux, Sylvie Deheul, Régis Bordet, Louise Carton, Olivier Cottencin, Renaud Jardri, Sophie Gautier
BACKGROUND: In France, baclofen is frequently used off-label for alcohol use disorder (AUD). Baclofen has been associated with diverse adverse events (AEs), but the causality of these AEs has never been properly assessed. METHODS/DESIGN: BACLOPHONE is a prospective multicenter cohort study conducted in the Hauts-de-France and Normandie French regions. BACLOPHONE consists of the phone-based monitoring of 792 patients during their first year of baclofen treatment for AUD...
December 21, 2016: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/27976201/hibiscus-acid-extract-biorefinery-process-and-ex-vivo-scientific-evidence-as-natural-skin-renewal
#15
A Lavaud, G Pichon, Y Rolland, M Roller, A Bily
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27971364/albuminuria-and-serum-creatinine-in-predicting-renal-function-decline-in-patients-with-diabetic-nephropathy-a-systematic-literature-review
#16
E Grubb, J Van der Vaart, K Norris, K E Smoyer, C Rolland
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27943401/fixism-and-conservation-science
#17
REVIEW
Alexandre Robert, Colin Fontaine, Simon Veron, Anne-Christine Monnet, Marine Legrand, Joanne Clavel, Stéphane Chantepie, Denis Couvet, Frédéric Ducarme, Benoît Fontaine, Frédéric Jiguet, Isabelle le Viol, Jonathan Rolland, François Sarrazin, Céline Teplitsky, Maud Mouchet
The field of biodiversity conservation has recently been criticised as relying on a fixist view of the living world, in which existing species constitute the targets of conservation efforts and simultaneously static states of reference, which is in apparent disagreement with evolutionary dynamics. Here, we argue that the ethical and theoretical frameworks underlying conservation research are based on macro-evolutionary reference processes rather than fixed reference states. We show how current species, phylogenetic, community and functional conservation approaches constitute short-term responses to short-term human effects on these reference processes, consistent with evolutionary principles...
December 10, 2016: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/27928506/get-the-most-out-of-blow-hormones-validation-of-sampling-materials-field-storage-and-extraction-techniques-for-whale-respiratory-vapour-samples
#18
Elizabeth A Burgess, Kathleen E Hunt, Scott D Kraus, Rosalind M Rolland
Studies are progressively showing that vital physiological data may be contained in the respiratory vapour (blow) of cetaceans. Nonetheless, fundamental methodological issues need to be addressed before hormone analysis of blow can become a reliable technique. In this study, we performed controlled experiments in a laboratory setting, using known doses of pure parent hormones, to validate several technical factors that may play a crucial role in hormone analyses. We evaluated the following factors: (i) practical field storage of samples on small boats during daylong trips; (ii) efficiency of hormone extraction methods; and (iii) assay interference of different sampler types (i...
2016: Conservation Physiology
https://www.readbyqxmd.com/read/27925143/is-the-25-hydroxy-vitamin-d-serum-concentration-a-good-marker-of-frailty
#19
T Krams, M Cesari, S Guyonnet, G Abellan Van Kan, C Cantet, B Vellas, Y Rolland
INTRODUCTION: The phenotype proposed by Fried and colleagues is a widely used operational definition of frailty defining such state of extreme vulnerability of older persons. Low serum 25-hydroxy-vitamin D (25(OH)D) has been suggested as biomarker of frailty in literature. STUDY DESIGN: Cross-sectional. OBJECTIVES: To explore the association of 25(OH)D concentrations with the frailty phenotype and its criteria. METHODS: 321 subjects referred by their general practitioner to a geriatric frailty clinic were assessed between January 1, 2013 and September 23, 2013...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27897430/validation-of-the-sarqol%C3%A2-a-specific-health-related-quality-of-life-questionnaire-for-sarcopenia
#20
Charlotte Beaudart, Emmanuel Biver, Jean-Yves Reginster, René Rizzoli, Yves Rolland, Ivan Bautmans, Jean Petermans, Sophie Gillain, Fanny Buckinx, Nadia Dardenne, Olivier Bruyère
BACKGROUND: A specific self-administrated health-related quality of life questionnaire for sarcopenia, the Sarcopenia and Quality Of Life (SarQoL®), has been recently developed. This questionnaire is composed of 55 items translated into 22 questions and organized into seven domains of quality of life. The objective of the present work is to evaluate the psychometric properties (discriminative power, validity, reliability, floor and ceiling effects) of the SarQoL® questionnaire. METHODS: Sarcopenic subjects were recruited in an outpatient clinic in Liège, Belgium and were diagnosed according to the algorithm developed by the European Working Group on Sarcopenia in Older People...
October 22, 2016: Journal of Cachexia, Sarcopenia and Muscle
keyword
keyword
13884
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"