keyword
MENU ▼
Read by QxMD icon Read
search

Intensive glycemic control

keyword
https://www.readbyqxmd.com/read/29330638/predictors-of-severe-postoperative-hyperglycemia-after-cardiac-surgery-in-infants-a-single-center-retrospective-observational-study
#1
Natsuhiro Yamamoto, Tomoya Irie, Shunsuke Takaki, Osamu Yamaguchi, Takahisa Goto
PURPOSE: Hyperglycemia is a common issue in infants after cardiac surgery for congenital heart disease. Poor glycemic control is suspected to be associated with adverse postoperative outcomes. This study was performed to investigate clinical factors contributing to hyperglycemia in the perioperative period in infats. METHODS: A total of 69 infants (aged 1-12 months) who were admitted to Yokohama City University Hospital Intensive Care Unit (ICU) after surgical repair of congenital heart diseases with cardiopulmonary bypass (CPB) were retrospectively analysed...
January 12, 2018: Journal of Anesthesia
https://www.readbyqxmd.com/read/29322300/glycemic-control-in-type-2-diabetes-from-medication-nonadherence-to-residual-vascular-risk
#2
Dario Giugliano, Maria Ida Maiorino, Giuseppe Bellastella, Katherine Esposito
Despite the availability of many new treatment options for type 2 diabetes, the proportion of patients achieving the HbA1c target < 7.0% remains around 50%. We put forward the hypothesis that the unchanged HbA1c results, observed in the last decade in type 2 diabetes patients, are also a consequence of medication nonadherence and clinical inertia. Poor medication-taking behavior is usually defined as medication nonadherence and is responsible for uncontrolled hemoglobin A1c level in 23% of cases. Medication nonadherence may also affect clinical outcomes, as diabetic patients with good adherence (≥80%) had a significant 10% lower rate of hospitalization events and a significant 28% lower rate of all-cause mortality when compared with patients with poor adherence (<80%)...
January 10, 2018: Endocrine
https://www.readbyqxmd.com/read/29314138/ovarian-markers-and-irregular-menses-among-women-with-type-1-diabetes-in-the-epidemiology-of-diabetes-interventions-and-complications-study
#3
C Kim, R S Miller, B H Braffett, Y Pan, V L Arends, A K Saenger, A Barnie, A V Sarma
OBJECTIVE: Women with type 1 diabetes have increased risk of infertility compared to women without diabetes even after adjustment for irregular menses, but etiologies are incompletely understood. Our aim was to examine the prevalence of abnormalities in ovarian markers consistent with polycystic ovary syndrome in women with type 1 diabetes and associations with irregular menses and diabetes-specific variables. DESIGN, PATIENTS, AND MEASUREMENTS: We conducted a secondary analysis of women in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC), a randomized trial and observational follow-up of intensive insulin therapy for type 1 diabetes...
January 4, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29308449/early-intensive-insulin-use-may-preserve-%C3%AE-cell-function-in-neonatal-diabetes-due-to-mutations-in-the-proinsulin-gene
#4
Lisa R Letourneau, David Carmody, Louis H Philipson, Siri Atma W Greeley
Although mutations in the proinsulin gene (INS) are the second most common cause of neonatal diabetes mellitus, the natural history of β-cell death and the most appropriate treatments remains unknown. We describe the management and outcome of two sisters with INS-mediated diabetes (S1 and S2) and suggest that more intensive insulin treatment of S2 may have resulted in better clinical outcomes. S1 was diagnosed with diabetes after presenting with serum glucose of 404 mg/dL (22.4 mmol/L) and started multiple daily insulin injections at age 4 months, followed by continuous subcutaneous insulin infusion (CSII) at age 42 months...
January 1, 2018: Journal of the Endocrine Society
https://www.readbyqxmd.com/read/29289983/intensified-blood-glucose-treatment-in-diabetic-patients-undergoing-a-liver-transplant-impact-on-graft-evolution-at-3%C3%A2-months-and-at-5%C3%A2-years
#5
A Ramos-Prol, D Hervás-Marín, B Rodríguez-Medina, M Rubio-Almanza, M Berenguer, Á Moya-Herraiz, J F Merino-Torres
PURPOSE: The debate about the impact of intensified hyperglycemia treatment is still ranging. The main objective was to assess whether intensive glycemic control in hospitalized diabetic patients undergoing a liver transplant is associated with a lower rate of graft rejection at 3 months and at 5 years post-transplant. METHODS: Cross-sectional study comparing a cohort of patients undergoing liver transplant in 2010 and 2011, in whom an intensive insulin protocol was applied, with a retrospective group of patients undergoing a liver transplant in 2005 and 2006, in whom a conventional insulin protocol was applied...
December 30, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29279299/characteristics-associated-with-decreased-or-increased-mortality-risk-from-glycemic-therapy-among-patients-with-type-2-diabetes-and-high-cardiovascular-risk-machine-learning-analysis-of-the-accord-trial
#6
Sanjay Basu, Sridharan Raghavan, Deborah J Wexler, Seth A Berkowitz
OBJECTIVE: Identifying patients who may experience decreased or increased mortality risk from intensive glycemic therapy for type 2 diabetes remains an important clinical challenge. We sought to identify characteristics of patients at high cardiovascular risk with decreased or increased mortality risk from glycemic therapy for type 2 diabetes using new methods to identify complex combinations of treatment effect modifiers. RESEARCH DESIGN AND METHODS: The machine learning method of gradient forest analysis was applied to understand the variation in all-cause mortality within the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial (N = 10,251), whose participants were 40-79 years old with type 2 diabetes, hemoglobin A1c (HbA1c) ≥7...
December 26, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29278829/efficacy-of-maternal-and-biological-parameters-at-the-time-of-diagnosis-of-gestational-diabetes-mellitus-in-predicting-neonatal-morbidity
#7
Guillaume Ducarme, François Desroys Du Roure, Aurélie Le Thuaut, Joséphine Grange, Jérôme Dimet, Ingrid Crepin-Delcourt
OBJECTIVE: Gestational diabetes mellitus (GDM) is independently associated with an increased risk of maternal-fetal complications. Improved glycemic control allows reducing perinatal morbidity and mortality and, specifically, the risk of macrosomia and shoulder dystocia which are the most common complications associated with GDM. Nonetheless, a need for early antenatal predictor of neonatal morbidity in women suffering from GDM is required. The objective of the study was to evaluate the efficacy of different maternal, biological, and antenatal parameters at the time of diagnosis of GDM or perinatal variables as predictors of neonatal morbidity...
December 19, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29276256/evaluation-of-insulin-use-and-hypoglycemia-in-hospitalized-elderly-patients
#8
Quyen N Bach, Rod A Gilmore, Melody C Sheffield, W Anthony Hawkins
Background: Routine administration of correctional insulin is no longer recommended as a primary strategy to treat hyperglycemia in hospitalized patients. Studies have demonstrated significant improvement in glycemic control in patients treated with basal and correctional insulin (B+C) versus correctional insulin alone (C). However, the effect of C or B+C on hypoglycemic events is not well understood. Objective: The objective of this study was to investigate the effect of B+C versus C on hypoglycemic events in hospitalized elderly patients...
December 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/29258520/metabolic-reponses-to-a-physical-exercise-session-in-women-with-excess-body-mass-randomized-clinical-trial
#9
Djeyne Silveira Wagmacker, Jefferson Petto, Amanda Silva Fraga, Jackeline Barbosa Matias, Sindy Kerole Andrade Mota, Luiz Erlon Araujo Rodrigues, Ana Marice Ladeia
BACKGROUND: There are various factors that influence the effect of physical exercise on the lipid profile, among them the body mass index and calorie expenditure of the exercise are some of the main factors. To test the hypothesis that a physical exercise session based on caloric expenditure may acutely modify the glycemia and lipid values of women with excess body mass. METHODS: The study included 66 women, randomly divided into two groups, control and experimental, with BMI of 29 ± 4...
December 19, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29251686/nil-whey-protein-effect-on-glycemic-control-after-intense-mixed-mode-training-in-type-2-diabetes
#10
Kim Alexander Gaffney, Adam Lucero, Lee Stoner, James Faulkner, Patricia Whitfield, Jeremy Krebs, David Stephen Rowlands
Although intense endurance and resistance exercise training and whey protein supplementation have both been shown to independently improve glycemic control, no known studies have examined the effect of high-intensity mixed-mode interval training (MMIT) and whey supplementation in adults with Type 2 diabetes (T2D). PURPOSE: This study aimed to determine if peritraining whey protein supplementation combined with MMIT can improve glycemic control. METHODS: In a double-blind, randomized, placebo-controlled trial, 24 men (55...
January 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29244792/tight-glycemic-control-in-critically-ill-pediatric-patients-a-meta-analysis-and-systematic-review-of-randomized-controlled-trials
#11
Yiyang Zhao, Yang Wu, Bo Xiang
BACKGROUND: There still are controversies in the impact of tight glycemic control (TGC) in critically ill children. The aim of this study was to assess the benefits and risks of TGC compared with conventional glycemic control (CGC) in critically ill pediatric patients admitted to the pediatric intensive care unit (PICU) by using data retrieved from randomized controlled trials (RCTs). METHOD: EMBASE, CNKI, PubMed and the Cochrane Database were searched for RCTs comparing TGC with CGC in critically ill children in PICU...
December 15, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29230472/individualized-glycemic-control-for-u-s-adults-with-type-2-diabetes-a-cost-effectiveness-analysis
#12
Neda Laiteerapong, Jennifer M Cooper, M Reza Skandari, Philip M Clarke, Aaron N Winn, Rochelle N Naylor, Elbert S Huang
Background: Intensive glycemic control in type 2 diabetes (glycated hemoglobin [HbA1c] level <7%) is an established, cost-effective standard of care. However, guidelines recommend individualizing goals on the basis of age, comorbidity, diabetes duration, and complications. Objective: To estimate the cost-effectiveness of individualized control versus uniform intensive control (HbA1c level <7%) for the U.S. population with type 2 diabetes. Design: Patient-level Monte Carlo-based Markov model...
December 12, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29218549/accuracy-and-reliability-of-a-subcutaneous-continuous-glucose-monitoring-device-in-critically-ill-patients
#13
S Rijkenberg, S C van Steen, J H DeVries, P H J van der Voort
Subcutaneous continuous glucose monitoring (CGM) may have benefits in achieving glycemic control in critically ill patients. The aim of this study was to assess the accuracy and reliability of the FreeStyle Navigator I in critically ill patients and to assess patient related factors influencing the accuracy and reliability. This study is a retrospective analysis of data from a randomized controlled trial conducted in a 20-bed mixed intensive care unit. Analytical accuracy, clinical accuracy and reliability were assessed against arterial blood glucose samples as reference...
December 7, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29218018/aerobic-interval-training-and-cardiometabolic-health-in-patients-with-type-2-diabetes-a-meta-analysis
#14
Shanhu Qiu, Xue Cai, Zilin Sun, Martina Zügel, Jürgen M Steinacker, Uwe Schumann
Vigorous to maximal aerobic interval training (INT) has received remarkable interest in improving cardiometabolic outcomes for type 2 diabetes patients recently, yet with inconsistent findings. This meta-analysis was aimed to quantify its effectiveness in type 2 diabetes. Randomized controlled trials (RCTs) were identified by searches of 3 databases to October 2017, which evaluated the effects of INT with a minimal training duration of 8 weeks vs. moderate-intensity continuous training (MICT) or non-exercise training (NET) among type 2 diabetes patients on outcomes including cardiorespiratory fitness, glycemic control, body composition, blood pressure, and lipid profiles...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29212333/-quo-vadis-diabetes-technology
#15
George Grunberger
Management of patients with diabetes mellitus who require intensive insulin therapy has changed dramatically. From urine and then whole blood glucose monitoring patients can now wear personal continuous glucose monitors; from using multiple insulin injections they can now deliver subcutaneous insulin continuously using ever-more sophisticated insulin pumps. With the current integration of continuous glucose monitoring and insulin pumps a new era is arriving when "smart" insulin pumps can automate insulin delivery to assure more stable glycemic control while minimizing episodes of hypoglycemia...
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/29212332/quo-vadis-diabetes-technology
#16
George Grunberger
Management of patients with diabetes mellitus who require intensive insulin therapy has changed dramatically. From urine and then whole blood glucose monitoring patients can now wear personal continuous glucose monitors; from using multiple insulin injections they can now deliver subcutaneous insulin continuously using ever-more sophisticated insulin pumps. With the current integration of continuous glucose monitoring and insulin pumps a new era is arriving when "smart" insulin pumps can automate insulin delivery to assure more stable glycemic control while minimizing episodes of hypoglycemia...
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/29209216/effects-of-intensive-control-of-glycemia-on-clinical-kidney-outcomes-in-type-2-diabetes-patients-compared-with-standard-control-a-meta-analysis
#17
Francisco Herrera-Gómez, María Asensio-González, Anunciación González-López, F Javier Álvarez
Background: Association between poor control of glycemia and the onset of microvascular complications in type 2 diabetes mellitus (T2DM) patients is a hard issue. However, it seems that the impact of pharmacological treatment is important only in early stages of diabetic nephropathy. We sought to examine whether intensive glycemic control is associated with improvement of clinical Chronic Kidney Disease (CKD) outcomes compared to standard glycemic control. Methods: Meta-analysis of published and unpublished randomized controlled trials (RCT) and post-hoc analysis of RCTs comparing anti-diabetic drugs and/or insulin (intensive control) vs...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29206237/one-year-follow-up-after-a-randomized-controlled-trial-of-a-130-g-day-low-carbohydrate-diet-in-patients-with-type-2-diabetes-mellitus-and-poor-glycemic-control
#18
Junko Sato, Akio Kanazawa, Chie Hatae, Sumiko Makita, Koji Komiya, Tomoaki Shimizu, Fuki Ikeda, Yoshifumi Tamura, Takeshi Ogihara, Tomoya Mita, Hiromasa Goto, Toyoyoshi Uchida, Takeshi Miyatsuka, Chie Ohmura, Takehito Watanabe, Kiyoe Kobayashi, Yoshiko Miura, Manami Iwaoka, Nao Hirashima, Hirotaka Watada
BACKGROUND & AIMS: Recently, we conducted a prospective randomized controlled trial (RCT) showing that a 6-month 130g/day low-carbohydrate diet (LCD) reduced HbA1c and BMI more than a calorie restricted diet (CRD). [1] To assess whether the benefits of the LCD persisted after the intensive intervention, we compared HbA1c and BMI between the LCD and CRD groups at 1 year after the end of the 6-month RCT. METHODS: Following the end of the 6-month RCT, patients were allowed to manage their own diets with periodic outpatient visits...
2017: PloS One
https://www.readbyqxmd.com/read/29193795/lower-mean-blood-glucose-during-short-term-intensive-insulin-therapy-is-associated-with-long-term-glycemic-remission-in-patients-with-newly-diagnosed-type-2-diabetes-evidence-based-recommendations-for-standardization
#19
Liehua Liu, Juan Liu, Lijuan Xu, Weijian Ke, Xuesi Wan, Hai Li, Xiaoying He, Liangjiao Wang, Xiaopei Cao, Haipeng Xiao, Yanbing Li
AIMS/INTRODUCTION: Optimal glycemic targets during short-term intensive insulin therapy in patients with newly diagnosed type 2 diabetes were not standardized. This study is performed to determine the optimal glycemic targets during the therapy by analyzing the impacts of glucose levels on therapeutic outcomes. MATERIALS AND METHODS: Nighty-five subjects with newly diagnosed type 2 diabetes were enrolled. Short-term intensive insulin therapy was carried out using insulin pump to achieve and maintain glycemic targets (FBG< 6...
November 30, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29183910/predictors-of-quality-of-life-and-other-patient-reported-outcomes-in-the-panorama-multinational-study-of-people-with-type-2-diabetes
#20
Clare Bradley, Eveline Eschwège, Pedro de Pablos-Velasco, Klaus G Parhofer, Dominique Simon, Hans Vandenberghe, Linda Gönder-Frederick
OBJECTIVE: PANORAMA, a nine-country cross-sectional type 2 diabetes study, investigated factors associated with quality of life (QoL), health status, and other patient-reported outcome measures (PROMs). RESEARCH DESIGN AND METHODS: Patients were randomly or consecutively selected from primary/secondary care. PROMs included the Audit of Diabetes-Dependent Quality of Life (ADDQoL) (generic QoL item and average weighted impact [AWI] scores), Diabetes Treatment Satisfaction Questionnaire (DTSQ) (patient- and physician-completed), Hypoglycemia Fear Survey-II worry subscale, and the EuroQoL-5 Dimension visual analog scale (EQ-VAS) measuring patient-reported health...
November 28, 2017: Diabetes Care
keyword
keyword
13876
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"