keyword
MENU ▼
Read by QxMD icon Read
search

Intensive glycemic control

keyword
https://www.readbyqxmd.com/read/28810024/effect-of-an-intensive-lifestyle-intervention-on-glycemic-control-in-patients-with-type-2-diabetes-a-randomized-clinical-trial
#1
Mette Yun Johansen, Christopher Scott MacDonald, Katrine Bagge Hansen, Kristian Karstoft, Robin Christensen, Maria Pedersen, Louise Seier Hansen, Morten Zacho, Anne-Sophie Wedell-Neergaard, Signe Tellerup Nielsen, Ulrik Wining Iepsen, Henning Langberg, Allan Arthur Vaag, Bente Klarlund Pedersen, Mathias Ried-Larsen
Importance: It is unclear whether a lifestyle intervention can maintain glycemic control in patients with type 2 diabetes. Objective: To test whether an intensive lifestyle intervention results in equivalent glycemic control compared with standard care and, secondarily, leads to a reduction in glucose-lowering medication in participants with type 2 diabetes. Design, Setting, and Participants: Randomized, assessor-blinded, single-center study within Region Zealand and the Capital Region of Denmark (April 2015-August 2016)...
August 15, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28806982/software-guided-versus-nurse-directed-blood-glucose-control-in-critically-ill-patients-the-logic-2-multicenter-randomized-controlled-clinical-trial
#2
Dieter Mesotten, Jasperina Dubois, Tom Van Herpe, Roosmarijn T van Hooijdonk, Ruben Wouters, Domien Coart, Pieter Wouters, Aimé Van Assche, Guy Veraghtert, Bart De Moor, Joost Wauters, Alexander Wilmer, Marcus J Schultz, Greet Van den Berghe
BACKGROUND: Blood glucose control in the intensive care unit (ICU) has the potential to save lives. However, maintaining blood glucose concentrations within a chosen target range is difficult in clinical practice and holds risk of potentially harmful hypoglycemia. Clinically validated computer algorithms to guide insulin dosing by nurses have been advocated for better and safer blood glucose control. METHODS: We conducted an international, multicenter, randomized controlled trial involving 1550 adult, medical and surgical critically ill patients, requiring blood glucose control...
August 14, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28761645/is-glycemia-control-in-canadians-with-diabetes-individualized-a-cross-sectional-observational-study
#3
Michael J Coons, Michelle Greiver, Babak Aliarzadeh, Christopher Meaney, Rahim Moineddin, Tyler Williamson, John Queenan, Catherine H Yu, David G White, Tara Kiran, Jennifer J Kane
OBJECTIVE: Diabetes guidelines recommend individualized glycemic targets: tighter control in younger, healthier patients and consideration of more moderate control in the elderly and those with coexisting illnesses. Our objective was to examine whether glycemic control varied by age and comorbidities in Canadian primary care. RESEARCH DESIGN AND METHODS: Cross-sectional study using data from the electronic medical records of 537 primary care providers across Canada; 30 416 patients with diabetes, aged 40 or above, with at least one encounter and one hemoglobin A1c (HbA1c) measurement between 1 January 2012 and 31 December 2013...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28757639/metabolic-effects-of-resistance-or-high-intensity-interval-training-among-glycemic-control-nonresponsive-children-with-insulin-resistance
#4
C Álvarez, R Ramírez-Campillo, R Ramírez-Velez, C Martínez, M Castro-Sepúlveda, A Alonso-Martínez, M Izquierdo
BACKGROUND: Little evidence exists on which variables of body composition or muscular strength mediates more glucose control improvements taking into account inter-individual metabolic variability to different modes of exercise training. OBJECTIVE: We examined 'mediators' to the effects of 6-weeks of resistance (RT) or high-intensity interval training (HIT) on glucose control parameters in physically inactive schoolchildren with insulin resistance. Secondly, we also determined both training-induce changes and the prevalence of responders (R) and non-responders (NR) to decrease the insulin resistance level...
July 31, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28754497/ultrasonography-improves-glycemic-control-by-detecting-insulin-derived-localized-amyloidosis
#5
Minoru Kikuchi, Naoki Hirokawa, Seiya Hagiwara, Hidetaka Nakayama, Shinji Taneda, Naoki Manda, Kouichi Sakata
We examined the feasibility of ultrasound diagnosis of insulin-derived localized amyloidosis (IDLA). In addition to ultrasound detectability and findings, the insulin absorption rate, insulin dosage and hemoglobin A1c (HbA1c) levels before and after shifting the insulin injection site were investigated for 22 cases of IDLA. The detectability of IDLA on ultrasound was 100%; 59.1% was palpable lumps and 40.9% was not palpable. The palpable type had lower echo intensity and were harder than the non-palpable type...
July 25, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28752262/discrimination-model-applied-to-urinalysis-of-patients-with-diabetes-and-hypertension-aiming-at-diagnosis-of-chronic-kidney-disease-by-raman-spectroscopy
#6
Elzo Everton de Souza Vieira, Jeyse Aliana Martins Bispo, Landulfo Silveira, Adriana Barrinha Fernandes
Higher blood pressure level and poor glycemic control in diabetic patients are considered progression factors that cause faster decline in kidney functions leading to kidney damage. The present study aimed to develop a quantification model of biomarkers creatinine, urea, and glucose by means of selected peaks of these compounds, measured by Raman spectroscopy, and to estimate the concentration of these analytes in the urine of normal subjects (G_N), diabetic patients with hypertension (G_WOL) patients with chronic renal failure doing dialysis (G_D)...
July 27, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28748706/the-development-of-new-composite-metrics-for-the-comprehensive-analytic-and-visual-assessment-of-hypoglycemia-using-the-hypo-triad
#7
Andreas Thomas, John Shin, Boyi Jiang, Chantal McMahon, Ralf Kolassa, Robert A Vigersky
BACKGROUND: Quantifying hypoglycemia has traditionally been limited to using the frequency of hypoglycemic events during a given time interval using data from blood glucose (BG) testing. However, continuous glucose monitoring (CGM) captures three parameters-a Hypo-Triad-unavailable with BG monitoring that can be used to better characterize hypoglycemia: area under the curve (AUC), time (duration of hypoglycemia), and frequency of daily episodes below a specified threshold. METHODS: We developed two new analytic metrics to enhance the traditional Hypo-Triad of CGM-derived data to more effectively capture the intensity of hypoglycemia (IntHypo) and overall hypoglycemic environment called the "hypoglycemia risk volume" (HypoRV)...
July 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28748705/the-comprehensive-glucose-pentagon-a-glucose-centric-composite-metric-for-assessing-glycemic-control-in-persons-with-diabetes
#8
Robert A Vigersky, John Shin, Boyi Jiang, Thorsten Siegmund, Chantal McMahon, Andreas Thomas
BACKGROUND: Composite metrics have the potential to provide more complete and clinically useful information about glycemic control than traditional individual metrics such as hemoglobin A1C, %/time/area under curve of hypoglycemia and hyperglycemia. METHODS: Using five key metrics that are derived from continuous glucose monitoring, we developed a new, multicomponent composite metric, the Comprehensive Glucose Pentagon (CGP) that demonstrates glycemic control both numerically and visually...
July 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28744255/glycemic-and-metabolic-effects-of-two-long-bouts-of-moderate-intensity-exercise-in-men-with-normal-glucose-tolerance-or-type-2-diabetes
#9
Saeed Reza Eshghi, Kevin Fletcher, Étienne Myette-Côté, Cody Durrer, Raniah Q Gabr, Jonathan P Little, Peter Senior, Craig Steinback, Margie H Davenport, Gordon J Bell, Dion R Brocks, Normand G Boulé
BACKGROUND: The glycemic and insulinemic responses following 30-60 min of exercise have been extensively studied, and a dose-response has been proposed between exercise duration, or volume, and improvements in glucose tolerance or insulin sensitivity. However, few studies have examined the effects of longer bouts of exercise in type 2 diabetes (T2D). Longer bouts may have a greater potential to affect glucagon, interleukin-6 (IL-6) and incretin hormones [i.e., glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP)]...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28720592/exercise-training-improves-but-does-not-normalize-left-ventricular-systolic-and-diastolic-function-in-adolescents-with-type-1-diabetes
#10
Silmara Gusso, Teresa Pinto, James C Baldi, José G B Derraik, Wayne S Cutfield, Tim Hornung, Paul L Hofman
OBJECTIVE: To determine the impact of 20 weeks of exercise training in aerobic capacity on left ventricular function and glycemic control in adolescents with and without type 1 diabetes. RESEARCH DESIGN AND METHODS: Fifty-three adolescents with type 1 diabetes (aged 15.6 years) were divided into two groups: exercise training (n = 38) and nontraining (n = 15). Twenty-two healthy adolescents without diabetes (aged 16.7 years) were included and, with the 38 participants with type 1 diabetes, participated in a 20-week exercise-training intervention...
July 18, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28711513/the-effectiveness-of-cognitive-function-stress-management-training-in-glycemic-control-in-children-and-in-mental-health-of-mother-caring-for-child-with-type-1-diabetes-mellitus
#11
Mozhdeh Saghaei, Pouya Omidi, Elham Hashemi Dehkordi, Parvin Safavi
AIM: The study was aimed to evaluate the effectiveness of a training course of cognitive-behavioral stress management in glycaemia regulation in children with type 1 diabetes mellitus as well as in mental health status of their mothers. MATERIALS AND METHODS: Fifty children with type 1 diabetes mellitus and their mothers were selected and randomly assigned into two groups. A group of mothers (n=25; as experimental one besides their children) passed a course, eight 2-h sessions, on the cognitive-behavioral and stress management, and the control group received the usual care...
July 3, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28707484/autoregressive-modeling-of-drift-and-random-error-to-characterize-a-continuous-intravascular-glucose-monitoring-sensor
#12
Tony Zhou, Jennifer L Dickson, J Geoffrey Chase
BACKGROUND: Continuous glucose monitoring (CGM) devices have been effective in managing diabetes and offer potential benefits for use in the intensive care unit (ICU). Use of CGM devices in the ICU has been limited, primarily due to the higher point accuracy errors over currently used traditional intermittent blood glucose (BG) measures. General models of CGM errors, including drift and random errors, are lacking, but would enable better design of protocols to utilize these devices. This article presents an autoregressive (AR) based modeling method that separately characterizes the drift and random noise of the GlySure CGM sensor (GlySure Limited, Oxfordshire, UK)...
July 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28700767/effect-of-non-insulin-based-glucose-lowering-therapies-on-cardiovascular-outcomes-in-patients-with-type-2-diabetes
#13
REVIEW
Szymon L Wiernek, Matthew A Cavender
Current guidelines for the treatment of patients with diabetes are focused on improving glycemic control and treating appropriate cardiovascular (CV) risk factors. Basic recommendations include blood pressure management with a goal of <140 mm Hg systolic pressure, statin therapy in all patients ≥40 years of age with diabetes (moderate intensity for all, and high intensity if at high risk of CVD events), and aspirin therapy in all adults at increased CV risk (10-year risk of CVD events >10%). Oral antihyperglycemic medications remain the cornerstone of treatment for optimizing glucose control in patients with diabetes...
June 2017: Journal of Family Practice
https://www.readbyqxmd.com/read/28699798/durability-of-response-to-dapagliflozin-a-review-of-long-term-efficacy-and-safety
#14
Serge Jabbour
BACKGROUND: Due to the chronic nature of type 2 diabetes (T2D), it is essential for an anti-diabetic drug to have durable efficacy and a good long-term safety profile. Dapagliflozin is a member of a unique class of anti-diabetic drugs that inhibit the sodium-glucose cotransporter 2 (SGLT-2) in the renal tubules and have an insulin-independent mechanism of action. In short-term studies (≤ 24 weeks), dapagliflozin reduced glycated hemoglobin (A1c), weight, and systolic blood pressure, and had a good safety profile...
July 31, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28684638/high-intensity-interval-exercise-and-glycemic-control-in-adolescents-with-type-one-diabetes-mellitus-a-case-study
#15
Emma J Cockcroft, Christopher Moudiotis, Julie Kitchen, Bert Bond, Craig A Williams, Alan R Barker
Current physical activity guidelines for youth with type 1 diabetes (T1D) are poorly supported by empirical evidence and the optimal dose of physical activity to improve glycemic control is unknown. This case report documents the effect of acute high-intensity interval exercise (HIIE) and moderate-intensity exercise (MIE) on 24-h glycemic control in three adolescents with T1D using continuous glucose monitoring. Results highlight varied individual response to exercise across the participants. In two participants both MIE and HIIE resulted in a drop in blood glucose during exercise (-38 to -42% for MIE and -21-46% in HIIE) and in one participant both MIE and HIIE resulted in increased blood glucose (+19% and + 36%, respectively)...
July 2017: Physiological Reports
https://www.readbyqxmd.com/read/28664624/adherence-to-a-lifestyle-program-for-youth-with-type-2-diabetes-and-its-association-with-treatment-outcome-in-the-today-clinical-trial
#16
Robert I Berkowitz, Marsha D Marcus, Barbara J Anderson, Linda Delahanty, Nisha Grover, Andrea Kriska, Lori Laffel, Amy Syme, Elizabeth Venditti, Dorothy J Van Buren, Denise E Wilfley, Patrice Yasuda, Kathryn Hirst
OBJECTIVE: To assess the association of proxies of behavioral adherence to the Treatment Options for type 2 Diabetes in Adolescents and Youth (TODAY) lifestyle program with changes in glycemic control and obesity in a multi-ethnic sample of youth with type 2 diabetes. METHODS: The TODAY clinical trial included an intensive lifestyle intervention to promote weight reduction. Adherence was assessed with measures of attendance at intervention sessions and rates of self-monitoring of diet and physical activity by participants and their caregivers...
June 30, 2017: Pediatric Diabetes
https://www.readbyqxmd.com/read/28660565/biopsychosocial-aspects-of-weight-management-in-type-1-diabetes-a-review-and-next-steps
#17
REVIEW
Kimberly A Driscoll, Karen D Corbin, David M Maahs, Richard Pratley, Franziska K Bishop, Anna Kahkoska, Korey K Hood, Elizabeth Mayer-Davis
PURPOSE OF REVIEW: This review aims to summarize the type 1 diabetes (T1D) and weight literature with an emphasis on barriers associated with weight management, the unique T1D-specific factors that impact weight loss success, maladaptive and adaptive strategies for weight loss, and interventions to promote weight loss. RECENT FINDINGS: Weight gain is associated with intensive insulin therapy. Overweight and obese weight status in individuals with T1D is higher than the general population and prevalence is rising...
August 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28659869/resting-metabolic-rate-does-not-change-in-response-to-different-types-of-training-in-subjects-with-type-2-diabetes
#18
Kristian Karstoft, Cecilie Fau Brinkløv, Ida Kær Thorsen, Jens Steen Nielsen, Mathias Ried-Larsen
BACKGROUND AND OBJECTIVES: Ambiguous results have been reported regarding the effects of training on resting metabolic rate (RMR), and the importance of training type and intensity is unclear. Moreover, studies in subjects with type 2 diabetes (T2D) are sparse. In this study, we evaluated the effects of interval and continuous training on RMR in subjects with T2D. Furthermore, we explored the determinants for training-induced alterations in RMR. METHODS: Data from two studies, both including T2D subjects, were encompassed in this manuscript...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28655584/biological-biochemical-and-histological-features-of-bradybaena-similaris-gastropoda-pulmonata-infected-by-heterorabditis-indica-rhabditida-heterorhabditidae-strain-lpp1
#19
Victor Menezes Tunholi, Vinícius Menezes Tunholi-Alves, Caio Oliveira Monteiro, Lidiane Cristina da Silva, Cláudia de Melo Dolinski, Rosane Nora Castro, Vânia Rita Elias Pinheiro Bittencourt, Jairo Pinheiro da Silva, Isabella Vilhena Freire Martins
This study investigated the possible biological, biochemical and histological changes in Bradybaena similaris(Gastropoda: Pulmonata) infected by Heterorhabditis indica (Rhabditida: Heterorhabditidae), strain LPP1. Two groups of 16 snails were formed: the control group (unexposed) and the treated group, which was exposed for three weeks to infective juveniles (J3) of H. indica LPP1. The experiment was conducted in duplicate, using a total of 64 snails. After the exposure period, the snails were dissected to collect the hemolymph and tissues, for evaluation of the physiological changes caused by the infection...
August 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28645517/glucose-control-diabetes-status-and-mortality-in-critically-ill-patients-the-continuum-from-intensive-care-unit-admission-to-hospital-discharge
#20
James S Krinsley, Paula Maurer, Sharon Holewinski, Roy Hayes, Douglas McComsey, Guillermo E Umpierrez, Stanley A Nasraway
OBJECTIVE: To describe the relationships among glycemic control, diabetes mellitus (DM) status, and mortality in critically ill patients from intensive care unit (ICU) admission to hospital discharge. PATIENTS AND METHODS: This is a retrospective investigation of 6387 ICU patients with 5 or more blood glucose (BG) tests and 4462 ICU survivors admitted to 2 academic medical centers from July 1, 2010, through December 31, 2014. We studied the relationships among mean BG level, hypoglycemia (BG level <70 mg/dL [to convert to mmol/L, multiply by 0...
July 2017: Mayo Clinic Proceedings
keyword
keyword
13876
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"