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Aggressive angiomyxoma

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https://www.readbyqxmd.com/read/28514296/clinicopathological-features-and-differential-diagnosis-of-aggressive-angiomyxoma-of-the-female-pelvis-5-case-reports-and-literature-review
#1
Hong Chen, Hongyan Zhao, Yan Xie, Mulan Jin
Aggressive angiomyxoma (AAM) is a rare mesenchymal tumor that usually occurs in the pelvis and perineum of young females. AAM can simulate Bartholin's gland cyst, abscess, lipoma, simple labial cyst, or other pelvic soft tissue tumors. Here we present five cases of AAM with mean age of 42. The patients mainly presented slow-growing mass in the abdomen and perineum (3 cases in the pelvis, 1 in the vulva, and 1 in the buttock). Color Doppler flow imaging revealed blood flow for the 3 pelvic lesions. Enhanced computed tomography and magnetic resonance imaging of the other 2 cases showed the typical "swirled" or "layered" structure characteristic...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28511222/cellular-angiofibroma-of-the-spermatic-cord
#2
M Aydin, H Uzuner, E Akgunes, A Bitkin, M Kadihasanoglu
Cellular angiofibromas are rare, slow-growing mesenchymal tumours, most often localised in the vulva and perineum of women. We present a case of a 60-year-old male with a 7-cm large cellular angiofibroma in the inguinal canal extending toward the testis, detected after inguinal herniorraphy. Inguinal orchiectomy was performed and the pathology report revealed a cellular angiofibroma containing a lot of mast cells in the stroma, which was collagenised with spindle-shaped cells and characterised by hyalinised vascular structures...
April 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28502834/a-rare-case-of-intravesical-angiomyofibroblastoma
#3
Phanindra Mohan Deka, Jaynil A Bagawade, Pallavi Deka, Ronica Baruah, Naushad Shah
OBJECTIVES: To study the first reported case of intravesical Angiomyofibroblastoma (AMFB). AMFB is an uncommon benign mesenchymal lesion, mostly described in the lower female genital tract, especially in the vulva and less commonly the vagina. It is rarely seen in the male genital tract. The importance of this rare neoplasm is related to its potential mimicry of more infiltrative and prognostically less favorable lesions, such as aggressive angiomyxomas, that are found in the same anatomic area...
May 11, 2017: Urology
https://www.readbyqxmd.com/read/28479778/paratesticular-aggressive-angiomyxoma-a-rare-case
#4
Muhamad Izwan Ismail, Yin Ping Wong, Guan Hee Tan, Xeng Inn Fam
Aggressive angiomyxoma (AAM) particularly testicular origin is a rare benign mesenchymal myxoid tumor which is locally aggressive, blatant for local recurrence, and may metastasize. It occurs mostly in females of childbearing age and extremely rare in males. AMM particular testicular origin is not reported in literature yet. This is a 65-year-old man who had a right scrotal swelling. Ultrasound scrotum showed a soft tissue tumor of the right testis. The patient underwent radical right orchidectomy of which histopathologically confirmed to be a paratesticular AAM with clear resection margins...
April 2017: Urology Annals
https://www.readbyqxmd.com/read/28476856/a-solitary-fibrous-tumour-mimicking-an-aggressive-angiomyxoma-liposarcoma
#5
Grace Hwei Ching Tan, Deanna Ng, Tiffany Hennedige, Melissa Teo
We present a case of a solitary fibrous tumour (SFT) resembling an aggressive angiomyxoma/liposarcoma on radiological imaging, causing significant diagnostic challenges preoperatively. A 76-year-old male was incidentally found to have a large pelvic mass on a CT scan. Further evaluation with an MRI scan confirmed a presacral mass containing fat and soft tissue components. It was inseparable from the sacrococcygeal spine, rectal serosa and the posterior wall of the urinary bladder, but no evidence of invasion was seen...
May 5, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28462172/aggressive-angiomyxoma-involving-penis-and-urethra-a-case-report
#6
Shivashankar Damodaran, Devakannan Gengan, Sashi T Walling
Aggressive angiomyxoma is a rare benign mesenchymal stromal tumour, characterized by locally infiltrative nature and a tendency for recurrence. Only a few cases of penile involvement have been reported in the literature so far. We report a case of aggressive penile angiomyxoma in a sixty-two-year-old obese, diabetic male patient. He presented with obstructive lower urinary tract symptoms (LUTS) and diffuse enlargement of the penis and scrotum. He was managed with excision, reduction scrotoplasty, internal urethrotomy, followed by Leuprolide therapy for prevention of recurrence...
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28442308/-18-f-fdg-pet-ct-in-aggressive-angiomyxoma-of-the-pelvis
#7
L Gilardi, M Vadrucci, A Pittaro, E Pennacchioli, S Rizzo
No abstract text is available yet for this article.
April 22, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28400400/transperineal-aggressive-angiomyxoma
#8
Pedro Pereira, Elisa Melo Abreu, Teresa Margarida Cunha, Inês Rolim
A 45-year-old woman with a history of total hysterectomy with adnexal preservation for uterine leiomyomas presented to our hospital with a right gluteal palpable mass, which she first noticed 6 months before and had progressively enlarged since then.Radiological studies revealed a 14 cm lesion with translevator growth that displaced rather than invaded adjacent structures, with a peculiar whorled pattern on T2-weighted MRI, which enhanced following gadolinium administration. CT-guided biopsy was performed, and in conjunction with imaging features the diagnosis of an aggressive angiomyxoma was assumed and confirmed following surgical excision...
April 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28352032/aggressive-angiomyxoma-of-transplanted-kidney-mimicking-posttransplant-lymphoproliferative-disorder
#9
Ujjwal Gorsi, Priyanka Naranje, Manish Rathi, Ritambhara Nada, Niranjan Khandelwal
Angiomyxoma is a scarce neoplasm arising from the soft tissues of perineum and pelvis, more commonly seen in the females. For such a tumor to arise in a renal allograft is rare and has previously been reported only in few case. We report a case of aggressive angiomyxoma arising de novo in the renal allograft nine-year posttransplantation. We describe its imaging features on ultrasound and computed tomography which closely mimic the more usual tumor of the transplanted kidney, posttransplant lymphoproliferative disorder and suggest that angiomyxoma may be considered as a differential diagnosis in a case of soft tissue mass arising within the renal allograft...
March 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28193643/an-unusual-vaginal-lump
#10
Stella Clare Seppings, Hashim Samir, Islam Abdelrahman
A 46-year-old woman presented with a 2-week history of a painless golf ball sized lump in her vagina. Despite transvaginal ultrasound scan, biopsy and MRI, it was only after surgery had been performed that it became clear what the nature of the mass actually was.Immunohistochemistry revealed the lump to be an aggressive angiomyxoma. Follow-up MRI showed residual (or recurrence of) angiomyxoma which was successfully treated with monthly injections of Prostap (leuprorelin acetate), a gonadotropin-releasing hormone agonist...
February 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28161377/aggressive-angiomyxoma-of-the-penis-the-first-case-report-in-a-9-month-old-infant
#11
Mohamed Atef Mohamed Ahmed, Mohamed Ahmed Uehelie, Abdihamid Mohamed Ali Rage, Ahmed Mohey, Yasser A Noureldin
Aggressive angiomyxoma (AA) is a rare, benign, mesenchymal tumor of the pelvis and perineum. It usually occurs in females at reproductive age. However, rare cases have been reported in male children. We present the first case of AA in the penis of a 9-month-old Somalian boy. The infant presented with large, nodular penile mass. The diagnosis was confirmed following complete surgical removal and histopathologic examination. Over a 6-month follow-up period, no recurrence was noticed. Therefore, we recommend complete surgical removal of the mass with wide safety margin and long-term follow-up for cases of AA...
February 1, 2017: Urology
https://www.readbyqxmd.com/read/28002623/comprehensive-screening-for-med12-mutations-in-gynaecological-mesenchymal-tumours-identified-morphologically-distinctive-mixed-epithelial-and-stromal-tumours
#12
Chang-Tsu Yuan, Wen-Chih Huang, Cheng-Han Lee, Ming-Chieh Lin, Chen-Hui Lee, Yu-Chien Kao, Hsuan-Ying Huang, Kuan-Ting Kuo, Jen-Chieh Lee
AIMS: MED12 exon 2 mutations have been identified in most uterine leiomyomas and mammary fibroepithelial tumours. MED12 has not been genotyped in most other gynaecological mesenchymal tumours. The purpose of this study was to determine the prevalence of MED12 mutations in uncommon gynaecological mesenchymal tumours. METHODS AND RESULTS: Sixty-eight uncommon gynaecological mesenchymal tumours were genotyped for MED12 exon 2, including 27 Müllerian adenosarcomas (including three tentatively diagnosed as 'variant adenosarcomas'), six cellular angiofibromas, six aggressive angiomyxomas, five angiomyofibroblastomas, five superficial myofibroblastomas, five atypical polypoid adenomyomas, and 14 endometrial stromal sarcomas...
December 21, 2016: Histopathology
https://www.readbyqxmd.com/read/27984053/aggressive-angiomyxoma-of-the-vulva-mimicking-clitoromegaly-in-a-young-child
#13
Masataka Kawamura, Fumi Matsumoto, Futoshi Matsui, Koji Yazawa, Kenji Shimada
Aggressive angiomyxoma (AAM) is a rare soft tissue tumor of mesenchymal origin that chiefly involves the vulvar and perineal region. In 90% of cases, AAM presents in women of reproductive age with a peak incidence in the fourth decade of life. To date, AAM of the vulva in young children and infancy has never been reported. We present a case of AAM of the vulva that was initially interpreted as clitoromegaly in a 3-year-old girl.
October 28, 2016: Urology
https://www.readbyqxmd.com/read/27974982/a-case-report-of-aggressive-angiomyxoma-in-pregnancy-do-hormones-play-a-role
#14
Theofano Orfanelli, Chi-Son Kim, Sally F Vitez, James Van Gurp, Neeti Misra
Aggressive angiomyxoma is a rare, locally invasive tumor that generally affects the perineum and pelvis of reproductive age females. Aggressive angiomyxoma is often misdiagnosed, resulting in the delay of the treatment. Case reports show increased growth of the tumor during pregnancy, thus suggesting a hormonal dependency. We report this rare condition in a 29-year-old primigravid female with a growing mass on the right labium majus at 20 weeks' gestation. The patient also developed a smaller mass on the left labium majus at 37 weeks' gestation...
2016: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27974964/aggressive-angiomyxoma-of-the-pelvis-and-perineum-a-case-report-and-literature-review
#15
Rashid Saif Al-Umairi, Atheel Kamona, Fadhila Mohammed Al-Busaidi
Aggressive angiomyxoma (AA) is a rare mesenchymal tumor that usually occurs in the pelvis and perineum of young females. AA can simulate Bartholin's gland cyst, abscess, lipoma, simple labial cyst, or other pelvic soft tissue tumors. Cross-sectional imaging, particularly magnetic resonance imaging (MRI), plays an essential role in the diagnosis and management of AA. We report a case of AA in a 38-year-old woman with typical MRI features. We also present the findings of a literature review on the radiological features of this disease...
November 2016: Oman Medical Journal
https://www.readbyqxmd.com/read/27920855/aggressive-angiomyxoma-case-report-and-review-of-the-literature
#16
John C Benson, Scott Gilles, Tina Sanghvi, James Boyum, Eric Niendorf
A 47-year-old female presented to clinic with a 5-year history of a left buttock mass. The patient's hemoglobin was low (9.7 g/dL); laboratory analysis was otherwise unremarkable. Ultrasound of the left gluteal region demonstrated a heterogeneous vascular solid lesion. Magnetic resonance and computed tomography imaging showed an enhancing mass extending from the left ischioanal fossa through the levator ani muscle into the pelvis. Biopsy revealed bland-appearing spindle-shaped cells positive for estrogen and progesterone receptors, consistent with an aggressive angiomyxoma...
December 2016: Radiology case reports
https://www.readbyqxmd.com/read/27803522/aggressive-angiomyxoma-of-vulva-in-pregnancy-a-case-report
#17
Rinchen Zangmo, Sunesh Kumar, Neeta Singh, Jyoti Meena
No abstract text is available yet for this article.
October 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27721642/an-aggressive-angiomyxoma-of-vulva-a-rare-entity-a-case-report
#18
Bishnu Prasad Das, Dipankar Baruah, Kaberee Bhuyan Medhi, Bharat Talukder
Aggressive angiomyxoma is a rare, locally invasive mesenchymal tumor predominantly presenting in women of reproductive age and also having a moderate-to-high risk for local relapse. Hence, it needs to be differentiated from other mesenchymal tumors occurring in this region. We present here a case of a 40-year-old female presenting with a large, fleshy, pedunculated mass on the right labia majora.
July 2016: Journal of Mid-life Health
https://www.readbyqxmd.com/read/27571990/clinicopathological-features-and-treatment-analysis-of-rare-aggressive-angiomyxoma-of-the-female-pelvis-and-perineum-a-retrospective-study
#19
Yin Sun, Lan Zhu, Xiaoyan Chang, Jie Chen, Jinghe Lang
The study was to evaluate the clinicopathological features of aggressive angiomyxoma (AAM) of the female pelvis and perineum and its treatments. This was a retrospective study of female patients with AAM admitted to our hospital. Clinical and pathological data were analyzed, as well as the postsurgical follow-up. Median age at initial presentation was 41 years. Thirteen patients had lesions involving adjacent organs. Eighteen patients underwent complete tumor resection, while one patient underwent partial tumor resection...
January 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/27552685/aggressive-angiomyxoma
#20
Carrie Chong
No abstract text is available yet for this article.
September 22, 2016: Nurse Practitioner
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