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https://www.readbyqxmd.com/read/28817703/quality-of-life-of-inguinal-hernia-patients-in-taiwan-the-application-of-the-hernia-specific-quality-of-life-assessment-instrument
#1
Chi-Cheng Huang, Feng-Chuan Tai, Tzung-Hsin Chou, Heng-Hui Lien, Jaan-Yeh Jeng, Thien-Fiew Ho, Ching-Shui Huang
BACKGROUND: With the development of prosthetic mesh and tension free techniques, the recurrence rate following inguinal hernia repair has been reduced, and hernia outcomes research should focus on post-operative quality of life and potential complications. STUDY DESIGN: A novel hernia quality of life assessment instrument, HERQL, was developed. The HERQL questionnaire comprises a 4-item summative pain score measuring pain and discomfort resulting from various strenuous activities...
2017: PloS One
https://www.readbyqxmd.com/read/28817617/comparison-of-lingual-mucosa-and-buccal-mucosa-grafts-used-in-inlay-urethroplasty-in-failed-hypospadias-of-pre-pubertal-boys-in-a-chinese-group
#2
Jin Hongyong, Chen Shuzhu, Wu Min, Ye Weijing, Liu Yidong
OBJECTIVE: The purpose of this study was to compare the outcomes of the buccal mucosa and lingual mucosa used in children who received multiple failed hypospadias surgeries. METHOD: We conducted a retrospective study of 62 children who received buccal or lingual mucosa graft urethroplasty in our hospital between 2012 and 2015. The ages ranged from 3.5-11 y. All cases included multiple failed hypospadias procedures, and the subjects received previous operations 2-3 times...
2017: PloS One
https://www.readbyqxmd.com/read/28817607/computer-aided-position-planning-of-miniplates-to-treat-facial-bone-defects
#3
Jan Egger, Jürgen Wallner, Markus Gall, Xiaojun Chen, Katja Schwenzer-Zimmerer, Knut Reinbacher, Dieter Schmalstieg
In this contribution, a software system for computer-aided position planning of miniplates to treat facial bone defects is proposed. The intra-operatively used bone plates have to be passively adapted on the underlying bone contours for adequate bone fragment stabilization. However, this procedure can lead to frequent intra-operatively performed material readjustments especially in complex surgical cases. Our approach is able to fit a selection of common implant models on the surgeon's desired position in a 3D computer model...
2017: PloS One
https://www.readbyqxmd.com/read/28817574/diffusion-tensor-imaging-profiles-reveal-specific-neural-tract-distortion-in-normal-pressure-hydrocephalus
#4
Nicole C Keong, Alonso Pena, Stephen J Price, Marek Czosnyka, Zofia Czosnyka, Elise E DeVito, Charlotte R Housden, Barbara J Sahakian, John D Pickard
BACKGROUND: The pathogenesis of normal pressure hydrocephalus (NPH) remains unclear which limits both early diagnosis and prognostication. The responsiveness to intervention of differing, complex and concurrent injury patterns on imaging have not been well-characterized. We used diffusion tensor imaging (DTI) to explore the topography and reversibility of white matter injury in NPH pre- and early after shunting. METHODS: Twenty-five participants (sixteen NPH patients and nine healthy controls) underwent DTI, pre-operatively and at two weeks post-intervention in patients...
2017: PloS One
https://www.readbyqxmd.com/read/28817568/an-optimal-strategy-for-epilepsy-surgery-disruption-of-the-rich-club
#5
Marinho A Lopes, Mark P Richardson, Eugenio Abela, Christian Rummel, Kaspar Schindler, Marc Goodfellow, John R Terry
Surgery is a therapeutic option for people with epilepsy whose seizures are not controlled by anti-epilepsy drugs. In pre-surgical planning, an array of data modalities, often including intra-cranial EEG, is used in an attempt to map regions of the brain thought to be crucial for the generation of seizures. These regions are then resected with the hope that the individual is rendered seizure free as a consequence. However, post-operative seizure freedom is currently sub-optimal, suggesting that the pre-surgical assessment may be improved by taking advantage of a mechanistic understanding of seizure generation in large brain networks...
August 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28817483/time-course-study-on-left-ventricular-function-in-a-rabbit-model-of-ischemia-reperfusion-injury-with-morphine-preconditioning
#6
Baihua Zhao, Chengxiao Liu, Darong Pu, Shi Zeng, Xi Dai, Minghui Liu
AIMS: The study aimed to analyze the left ventricular longitudinal function in a rabbit model of myocardial ischemia-reperfusion with morphine preconditioning through strain rate imaging and evaluate the effect of morphine preconditioning. METHODS: A myocardial ischemia-reperfusion model was induced by occlusion and recanalization of the coronary artery in forty male New Zealand white rabbits, which were divided into a sham group, morphine group, and vehicle control group...
August 15, 2017: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/28817439/faculty-development-for-the-operating-room-an-examination-of-the-effectiveness-of-an-intraoperative-teaching-course-for-surgeons
#7
Aimee K Gardner, Matthew D Timberlake, Brian J Dunkin
OBJECTIVE: We describe a half-day faculty development course designed to equip surgical educators with evidence-based teaching frameworks shown to promote learning in the operating room (OR). We hypothesize that participating faculty will deliver improved instruction as perceived by residents. METHODS: Residents anonymously rated faculty teaching behaviors among whom they had recently worked in the OR (minimum 3 cases in preceding 6 months) using the Briefing - Intraoperative teaching - Debriefing Assessment Tool (BIDAT; 1 = never, 5 = always)...
August 16, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28816346/homocysteine-lowering-interventions-for-preventing-cardiovascular-events
#8
REVIEW
Arturo J Martí-Carvajal, Ivan Solà, Dimitrios Lathyris, Mark Dayer
BACKGROUND: Cardiovascular disease, which includes coronary artery disease, stroke and peripheral vascular disease, is a leading cause of death worldwide. Homocysteine is an amino acid with biological functions in methionine metabolism. A postulated risk factor for cardiovascular disease is an elevated circulating total homocysteine level. The impact of homocysteine-lowering interventions, given to patients in the form of vitamins B6, B9 or B12 supplements, on cardiovascular events has been investigated...
August 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28815843/ilizarov-technique-and-limited-surgical-methods-for-correction-of-post-traumatic-talipes-equinovarus-in-children
#9
Xiao Jian Wang, Feng Chang, Yunxing Su, Bin Chen, Jie-Fu Song, Xiao-Chun Wei, Lei Wei
BACKGROUND: The objective of this study was to evaluate the efficacy and safety of using Ilizarov invasive distraction technique combined with limited surgical operations in the treatment of post-traumatic talipes equinovarus in children. METHODS: Eighteen cases of post-traumatic deformed feet in 15 patients who received the treatment of Ilizarov frame application, limited soft-tissue release or osteotomy were selected in this study. After removal of the frame, an ankle-foot orthosis was used continuously for another 6-12 months...
August 16, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28815459/a-roadmap-for-reducing-cardiac-device-infections-a-review-of-epidemiology-pathogenesis-and-actionable-risk-factors-to-guide-the-development-of-an-infection-prevention-program-for-the-electrophysiology-laboratory
#10
REVIEW
Westyn Branch-Elliman
PURPOSE OF REVIEW: Cardiovascular implantable electronic device (CIED) infections are highly morbid, common, and costly, and rates are increasing (Sohail et al. Arch Intern Med 171(20):1821-8 2011; Voigt et al. J Am Coll Cardiol 48(3):590-1 2006). Factors that contribute to the development of CIED infections include patient factors (comorbid conditions, self-care, microbiome), procedural details (repeat procedure, contamination during procedure, appropriate pre-procedural prep, and antimicrobial use), environmental and organizational factors (patient safety culture, facility barriers, such as lack of space to store essential supplies, quality of environmental cleaning), and microbial factors (type of organism, virulence of organism)...
August 16, 2017: Current Infectious Disease Reports
https://www.readbyqxmd.com/read/28814400/mediation-and-modification-of-genetic-susceptibility-to-obesity-by-eating-behaviors
#11
Blandine de Lauzon-Guillain, Emma Ad Clifton, Felix R Day, Karine Clément, Soren Brage, Nita G Forouhi, Simon J Griffin, Yves Akoli Koudou, Véronique Pelloux, Nicholas J Wareham, Marie-Aline Charles, Barbara Heude, Ken K Ong
Background: Many genetic variants show highly robust associations with body mass index (BMI). However, the mechanisms through which genetic susceptibility to obesity operates are not well understood. Potentially modifiable mechanisms, including eating behaviors, are of particular interest to public health.Objective: Here we explore whether eating behaviors mediate or modify genetic susceptibility to obesity.Design: Genetic risk scores for BMI (BMI-GRSs) were calculated for 3515 and 2154 adults in the Fenland and EDEN (Etude des déterminants pré et postnatals de la santé et du développement de l'enfant) population-based cohort studies, respectively...
August 16, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28813082/middle-cerebral-artery-aneurysms-aneurysm-angiographic-morphology-and-its-relation-to-pre-operative-and-intra-operative-rupture
#12
Iracema Araújo Estevão, Bruno Camporeze, Antonio Santos de Araujo, Breno Nery, Ápio Claudio Martins Antunes, Timothy R Smith, Paulo Henrique Pires de Aguiar
Objective: Correlate the middle cerebral artery bifurcation aneurysm morphology with the pre-operative and intra-operative risk of rupture. Methods: Forty patients with 46 middle cerebral artery bifurcation aneurysms were treated microsurgically by the same surgeon. Aneurysms were classified according to shape and the Fisher test was applied to analyze the effect of morphology on the pre-operative and intra-operative rupture. Results: Pre-operative and intra-operative ruptures were observed in 8/46 patients (17...
August 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28812595/compulsive-like-sufentanil-vapor-self-administration-in-the-rat
#13
Janaina Cm Vendruscolo, Brendan J Tunstall, Stephanie A Carmack, Brooke E Schmeichel, Emily G Lowery-Gionta, Maury Cole, Olivier George, Sophia Vandewater, Michael Taffe, George F Koob, Leandro F Vendruscolo
Opioid misuse is at historically high levels in the United States, with inhalation (ie, smoking, and vaping) being one of the most common routes of consumption. We developed and validated a novel preclinical model of opioid self-administration by inhalation that does not require surgery and reliably produces somatic and motivational signs of dependence. Rats were trained to perform an operant response (nosepoke) to receive 10 s of vaporized sufentanil, a potent opioid, in 2 h daily sessions. Rats readily and concentration-dependently self-administered vaporized sufentanil...
August 16, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28812407/scaling-the-punctum-and-canaliculus-in-patients-undergoing-punctoplasty-surgery-a-prospective-cohort-study
#14
Nisha Nesaratnam, Krisztina Emeriewen, Julie Smith, Beena David, James Wawrzynski, Anant Sharma, George M Saleh
Optical Coherence Tomography (OCT) is a safe and non-invasive method of high-resolution cross-sectional imaging of tissue microstructures using infrared radiation. This study investigates how the appearance of the punctum and proximal canaliculus differs pre- and post-operatively in patients undergoing punctoplasty surgery. Patients with symptomatic punctal stenosis warranting punctoplasty surgery were prospectively invited to enrol from a single centre. Spectral OCT images of the lower punctae were captured with a Topcon 3D OCT 2000 machine pre- and post-operatively (at their follow-up appointment)...
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28812281/preclinical-development-of-an-automated-injection-device-for-intradermal-delivery-of-a-cell-based-therapy
#15
Giulia Leoni, Alex Lyness, Patrick Ginty, Rindi Schutte, Gopalan Pillai, Gayatri Sharma, Paul Kemp, Natalie Mount, Michaela Sharpe
Current methods for intradermal delivery of therapeutic products in clinical use include manual injection via the Mantoux technique and the use of injection devices, primarily developed for the delivery of vaccines and small molecules. A novel automated injection device is presented specifically designed for accurate delivery of multiple doses of product through a number of adjustable injection parameters, including injection depth, dose volume and needle insertion speed. The device was originally conceived for the delivery of a cell-based therapy to patients with skin wounds caused by epidermolysis bullosa...
August 15, 2017: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/28812157/augmented-reality-in-a-tumor-resection-model
#16
Pauline Chauvet, Toby Collins, Clement Debize, Lorraine Novais-Gameiro, Bruno Pereira, Adrien Bartoli, Michel Canis, Nicolas Bourdel
BACKGROUND: Augmented Reality (AR) guidance is a technology that allows a surgeon to see sub-surface structures, by overlaying pre-operative imaging data on a live laparoscopic video. Our objectives were to evaluate a state-of-the-art AR guidance system in a tumor surgical resection model, comparing the accuracy of the resection with and without the system. Our system has three phases. Phase 1: using the MRI images, the kidney's and pseudotumor's surfaces are segmented to construct a 3D model...
August 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28811990/clinical-outcomes-of-total-disc-replacement-versus-anterior-lumbar-interbody-fusion-for-surgical-treatment-of-lumbar-degenerative-disc-disease
#17
Tobias A Mattei, Jennifer Beer, Alisson R Teles, Azeem A Rehman, Jean Aldag, Dzung Dinh
STUDY DESIGN: The authors performed a retrospective controlled study of patients diagnosed with lumbar degenerative disc disease who received surgical intervention (either total disc replacement [TDR]/Activ-L or anterior lumbar interbody fusion [ALIF]) at a single tertiary-care hospital from 2007-2010. OBJECTIVES: To investigate the clinical outcomes after TDR in comparison with ALIF for surgical treatment of lumbar degenerative disc disease (DDD). METHODS: Analyzed data included intra-operative blood loss, time to return to work, and clinical outcomes as evaluated through the Oswestry Disability Index (ODI) and the Visual Analog Scale (VAS) pain questionnaires pre-operatively and at 6 weeks, 3 months, 6 months, and 1 year postoperative follow-up...
August 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28811796/visual-outcome-after-phacoemulsification-with-lens-implant-in-diabetic-and-non-diabetic-patients-a-comparative-study
#18
Abdul Rashid Shaikh, Abdul Haleem Mirani, Muhammad Saleh Memon, Muhammad Faisal Fahim
OBJECTIVE: To compare the visual outcomes of phacoemulsification surgery with intraocular lens (IOL) in persons with and without diabetes at end of follow-up. METHODS: This was a comparative, cross sectional, observational study with Non-probability, purposive sampling. After approval from "Research Ethical Committee of Isra Post-graduate Institute of Ophthalmology Karachi, 92 patients with cataract in one eye were selected. Patients were divided into two groups...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28811764/revisional-laparoscopic-sleeve-gastrectomy-in-failed-gastric-banding-and-effects-of-exercise-and-frequent-sweet-eating-on-its-outcome
#19
Hamed A AlWadaani, Abdul Qadeer
OBJECTIVE: To find out effectiveness of revisional laparoscopic sleeve gastrectomy (RLSG) in the patients who had laparoscopic adjustable gastric banding (LAGB) and failed to reduce or regained the weight and effectiveness of sweet abstaining and exercise on postoperative weight loss. METHODS: This retrospective observational study was conducted at AlMoosa Hospital, Al-Ahsa, Kingdom of Saudi Arabia from December 2011 to November 2016. The patients who failed to reduce, regained the weight or had complications after LAGB, were performed RLSG...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28811161/acceleration-of-electroactive-anammox-electroammox-start-up-by-switching-acetate-pre-acclimated-biofilms-to-electroammox-biofilms
#20
Jiahuan Tang, Shanshan Chen, Lingyan Huang, Xiaojuan Zhong, Guiqin Yang, Shungui Zhou
In this study, an operational method of switching acetate media to ammonium media after the formation of stable acetate-oxidizing biofilms (ACAM mode), was developed. The results showed that the start-up time was shortened to 48days in the ACAM mode compared to the AM (always ammonium media) mode (>120days), and an ammonia removal rate of 82±3% was achieved successfully and sustainably in the ACAM mode during the following long-term operation of more than 2months. Moreover, the ACAM mode was more efficient in enriching both electroammox bacteria and electricigens with Ignavibacteriaceae, Geobacteraceae and Nitrosomonadaceae as dominant families, which could favour the formation of high-performance electroammox biofilms...
August 9, 2017: Bioresource Technology
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