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Laparoscopic cholecystectomy antibiotic prophylaxis

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https://www.readbyqxmd.com/read/29067946/can-post-operative-antibiotic-prophylaxis-following-elective-laparoscopic-cholecystectomy-be-completely-done-away-with-in-the-indian-setting-a-prospective-randomised-study
#1
Vikram Singh Chauhan, P L Kariholu, Sabyasachi Saha, Himanshu Singh, Jasmine Ray
Premise and Objective: Elective laparoscopic cholecystectomy (LC) has low risk for post-operative infectious complications; still most clinicians use persistent post-operative prophylactic antibiotics out of habit, tradition, or simply as defensive practice due to evolving medicolegal implications of a large number of surgeries being showcased as daycare or next day discharge procedures. This randomised prospective trial was done to test the need for such prophylaxis in cases of elective LC in a rural/semi-urban setting...
October 23, 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28375803/routine-use-of-prophylactic-antibiotics-during-laparoscopic-cholecystectomy-does-not-reduce-the-risk-of-surgical-site-infections
#2
RANDOMIZED CONTROLLED TRIAL
Pinar Sarkut, Sadik Kilicturgay, Hikmet Aktas, Yilmaz Ozen, Ekrem Kaya
BACKGROUND: Laparoscopic cholecystectomy (LC) is the gold standard for the treatment of symptomatic gallbladder stones. As infections are rare in uncomplicated LC, it is widely accepted that prophylactic antibiotics need not be administered, and guidelines do not support routine antibiotic prophylaxis during elective LC. However, routine antibiotic prophylaxis for elective LC is still popular in many clinical settings. We investigated this situation in our department. METHOD: This randomized double-blind controlled study included 570 patients who underwent LC between March 2007 and February 2010...
July 2017: Surgical Infections
https://www.readbyqxmd.com/read/28071948/current-practice-of-antibiotic-prophylaxis-during-elective-laparoscopic-cholecystectomy
#3
Caw Macano, E A Griffiths, R S Vohra
INTRODUCTION Current guidelines do not recommend antibiotic prophylaxis in elective laparoscopic cholecystectomy. Despite this, there is wide variation in antibiotic prophylaxis during cholecystectomy in population-based studies. The aim of this survey was to establish the current rationale for antibiotic prophylaxis in elective laparoscopic cholecystectomy. METHODS A short questionnaire was designed and disseminated across collaborators for a population-based study investigating outcomes following cholecystectomy and via the Association of Upper Gastrointestinal Surgeons, Researchgate and Surginet membership...
March 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/27759780/antibiotic-prophylaxis-in-laparoscopic-cholecistectomy-is-it-worth-doing
#4
RANDOMIZED CONTROLLED TRIAL
Márcio Alexandre Terra Passos, Pedro Eder Portari-Filho
Background: Elective laparoscopic cholecystectomy has very low risk for infectious complications, ranging the infection rate from 0.4% to 1.1%. Many surgeons still use routine antibiotic prophylaxis. Aim: Evaluate the real impact of antibiotic prophylaxis in elective laparoscopic cholecystectomies in low risk patients. Method: Prospective, randomized and double-blind study. Were evaluated 100 patients that underwent elective laparoscopic cholecystectomy divided in two groups: group A (n=50), patients that received prophylaxis using intravenous Cephazolin (2 g) during anesthetic induction and group B (n=50), patients that didn't receive any antibiotic prophylaxis...
July 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/27343792/marfan-syndrome-new-diagnostic-criteria-same-anesthesia-care-case-report-and-review
#5
REVIEW
Maria Rita Araújo, Céline Marques, Sara Freitas, Rita Santa-Bárbara, Joana Alves, Célia Xavier
BACKGROUND: Marfan's Syndrome (MFS) is a disorder of connective tissue, mainly involving the cardiovascular, musculoskeletal, and ocular systems. The most severe problems include aortic root dilatation and dissection. Anesthetic management is vital for the improvement on perioperative morbidity. CASE REPORT: 61-year-old male with MFS, presenting mainly with pectus carinatum, scoliosis, ectopia lens, previous spontaneous pneumothorax and aortal aneurysm and dissection submitted to thoracoabdominal aortic prosthesis placement...
July 2016: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/27157204/-marfan-syndrome-new-diagnostic-criteria-same-anesthesia-care-case-report-and-review
#6
Maria Rita Araújo, Céline Marques, Sara Freitas, Rita Santa-Bárbara, Joana Alves, Célia Xavier
BACKGROUND: Marfan's Syndrome (MFS) is a disorder of connective tissue, mainly involving the cardiovascular, musculoskeletal, and ocular systems. The most severe problems include aortic root dilatation and dissection. Anesthetic management is vital for the improvement on perioperative morbidity. CASE REPORT: 61-year-old male with MFS, presenting mainly with pectus carinatum, scoliosis, ectopia lens, previous spontaneous pneumothorax and aortal aneurysm and dissection submitted to thoracoabdominal aortic prosthesis placement...
July 2016: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/26637110/safety-and-efficacy-of-antibiotic-prophylaxis-in-patients-undergoing-elective-laparoscopic-cholecystectomy-a-systematic-review-and-meta-analysis
#7
REVIEW
Bo Liang, Min Dai, Zhenhong Zou
BACKGROUND AND AIM: Owing to persistent controversy regarding the use of routine antibiotic prophylaxis in patients undergoing elective laparoscopic cholecystectomy and the availability of several new randomized controlled trials (RCTs), we conducted an up-to-date meta-analysis to provide the best current evidence. The aim of the article is to evaluate the safety and efficacy of routine antibiotic prophylaxis in low-risk patients undergoing elective laparoscopic cholecystectomy. METHODS: We conducted a comprehensive literature review of the PubMed, Embase, and Cochrane Library databases for RCTs that compared antibiotic prophylaxis versus placebo or no antibiotics in low-risk patients undergoing elective laparoscopic cholecystectomy...
May 2016: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/26278661/prophylactic-laparoscopic-cholecystectomy-in-adult-sickle-cell-disease-patients-with-cholelithiasis-a-prospective-cohort-study
#8
Mirko Muroni, Valeria Loi, François Lionnet, Robert Girot, Sidney Houry
INTRODUCTION: Prophylactic laparoscopic cholecystectomy remains controversial and has been discussed for selected subgroups of patients with asymptomatic cholelithiasis who are at high risk of developing complications such as chronic haemolytic conditions. Cholelithiasis is a frequent condition for patients with sickle cell disease (SCD). Complications from cholelithiasis may dramatically increase morbidity for these patients. Our objective was to evaluate the effectiveness of prophylactic cholecystectomy in SCD patients with asymptomatic gallbladder stones...
October 2015: International Journal of Surgery
https://www.readbyqxmd.com/read/25543880/antibiotic-prophylaxis-in-elective-laparoscopic-cholecystectomy-is-useless-a-prospective-multicenter-study
#9
MULTICENTER STUDY
Erasmo Spaziani, Marcello Picchio, Annalisa Di Filippo, Ettore Greco, Alessandra Cerioli, Maurizio Maragoni, Giuliano Faccì, Pierino Lucarelli, Giusppe Marino, Franco Stagnitti, Piero Narilli
AIM: We performed a prospective study to evaluate the effect of antibiotic prophylaxis (AP) on the incidence of infection in elective laparoscopic cholecystectomy (LC). MATERIAL OF STUDY: All patients were at low-medium anesthetic and infectious risk and underwent LC for benign disease. At induction of anesthesia 41 patients received ampicillin-sulbactam 3g, 40 patients received ciprofloxacin 400mg intravenously, and 53 patients received no AP. RESULTS: Postoperative infection was observed in 11 patients (8...
May 2015: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/25192389/antibiotic-prophylaxis-in-laparoscopic-cholecystectomy-a-randomized-controlled-trial
#10
RANDOMIZED CONTROLLED TRIAL
Yoichi Matsui, Sohei Satoi, Masaki Kaibori, Hideyoshi Toyokawa, Hiroaki Yanagimoto, Kosuke Matsui, Morihiko Ishizaki, A-Hon Kwon
BACKGROUND: Recent meta-analyses concluded that antibiotic prophylaxis is not warranted in low-risk laparoscopic cholecystectomy. However, most trials in the meta-analyses had a relatively small sample size and were statistically underpowered. In addition, many of the trials mentioned potential cost savings owing to the elimination of prophylactic antibiotics. However, no trial has statistically estimated the cost effectiveness. To evaluate the results of meta-analyses, we conducted a randomized controlled trial on the role of prophylactic antibiotics in low-risk laparoscopic cholecystectomy with an adequate sample size...
2014: PloS One
https://www.readbyqxmd.com/read/25098088/role-of-prophylactic-antibiotics-in-low-risk-elective-laparoscopic-cholecystectomy-is-there-a-need
#11
RANDOMIZED CONTROLLED TRIAL
Muhammad Ali Naqvi, Adnan Mehraj, Raja Ejaz, Amer Mian
BACKGROUND: Elective cholecystectomy for symptomatic gall stone disease carries low risk of postoperative infective complications. Yet the routine use of prophylactic antibiotic is in vogue in many centres. The aim of this study was to find out the efficacy of antibiotic prophylaxis in preventing postoperative infective complications in low risk elective laparoscopic cholecystectomy patients. METHOD: Randomised controlled trial was carried out in our hospital from 1st Nov 2009 to 15th Oct 2011...
January 2013: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/25052130/the-efficacy-of-cefazolin-in-reducing-surgical-site-infection-in-laparoscopic-cholecystectomy-a-prospective-randomized-double-blind-controlled-trial
#12
RANDOMIZED CONTROLLED TRIAL
Sakchai Ruangsin, Supparerk Laohawiriyakamol, Somkiat Sunpaweravong, Somrit Mahattanobon
BACKGROUND: A prophylactic antibiotic is recommended in open cholecystectomy surgeries, but in laparoscopic cholecystectomies such prophylaxis is controversial. Recent reviews have not found conclusive evidence that routine prophylaxis, especially in low risk patients, is effective. This clinical trial was undertaken to evaluate the efficacy of cefazolin in reducing surgical site infection SSI in laparoscopic cholecystectomies in a sample not screened for high or low risk patients. METHODS: A randomized double-blind controlled trial was conducted in a single university hospital...
April 2015: Surgical Endoscopy
https://www.readbyqxmd.com/read/24992423/a-national-audit-of-antibiotic-prophylaxis-in-elective-laparoscopic-cholecystectomy
#13
H E Graham, A Vasireddy, D Nehra
INTRODUCTION: Laparoscopic surgeons in Great Britain and Ireland were surveyed to assess their use of antibiotic prophylaxis in elective laparoscopic cholecystectomy. This followed a Cochrane review that found no evidence to support the use of antibiotic prophylaxis in routine cases. METHODS: Data were collected on routine use of antibiotics in elective laparoscopic cholecystectomy, and how that was influenced by factors such as bile spillage, patient co-morbidities and surgeons' experience...
July 2014: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/24338847/outcomes-of-antibiotic-prophylaxis-in-acute-cholecystectomy-in-a-population-based-gallstone-surgery-registry
#14
G Jaafar, G Persson, B Svennblad, G Sandblom
BACKGROUND: The aim of this study was to assess the effect of antibiotic prophylaxis (AP) on postoperative infections in acute cholecystectomy. METHODS: The study was based on acute cholecystectomies registered in the nationwide Swedish Register for Gallstone Surgery and Endoscopic Retrograde Cholangiopancreatography (GallRiks) between 2006 and 2010. The association between AP and the risk of postoperative infectious complications was tested in a multivariable regression analysis, with stepwise addition of age, sex, duration of operation, indication for surgery, surgical approach (laparoscopic versus open) and American Society of Anesthesiologists (ASA) fitness grade as co-variables...
January 2014: British Journal of Surgery
https://www.readbyqxmd.com/read/23838497/a-selective-antibiotic-prophylaxis-policy-for-laparoscopic-cholecystectomy-is-effective-in-minimising-infective-complications
#15
F Yanni, P Mekhail, G Morris-Stiff
INTRODUCTION: It has been demonstrated previously that the identification of bactibilia during cholecystectomy is associated with the presence of one or more risk factors: acute cholecystitis, common duct stones, emergency surgery, intraoperative findings and age >70 years. Current evidence-based guidance on antibiotic prophylaxis during laparoscopic cholecystectomy (LC) is based on elective procedures and does not take into account these factors. The aim of this study was to assess the effectiveness of a selective antibiotic prophylaxis policy limited to high risk patients undergoing LC with the development of port site infections as the primary endpoint...
July 2013: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/23530809/guidelines-for-antibiotic-prophylaxis-of-cholecystectomies-in-norwegian-hospitals
#16
Oliver Kacelnik, Torunn Alberg, Odd Mjaland, Hanne Eriksen, Finn Egil Skjeldestad
BACKGROUND: Antibiotic resistance is a global problem that affects the surgical patient population. Guidelines for antibiotic use have been shown to be effective both in terms of protecting individuals undergoing surgery and ensuring appropriate prescribing. More than 5,000 cholecystectomies are performed each year in Norway. However, there are no national guidelines for prophylactic antibiotics. The aim of this study was to chart the existence of local guidelines and whether they were updated and used...
April 2013: Surgical Infections
https://www.readbyqxmd.com/read/23325144/the-swedish-registry-of-gallstone-surgery-and-endoscopic-retrograde-cholangiopancreatography-gallriks-a-nationwide-registry-for-quality-assurance-of-gallstone-surgery
#17
Lars Enochsson, Anders Thulin, Johanna Osterberg, Gabriel Sandblom, Gunnar Persson
OBJECTIVES: To describe the process of initiating and organizing a nationwide validated web-based quality registry of gallstone surgery and endoscopic retrograde cholangiopancreatography (ERCP) and to present some clinical data and the impact the registry has had on the clinical treatment of gallstones. DESIGN: Observational, population-based registry study. SETTING: Data from the nationwide Swedish Registry of Gallstone Surgery and ERCP (GallRiks)...
May 2013: JAMA Surgery
https://www.readbyqxmd.com/read/23063084/routine-use-of-antibiotic-prophylaxis-in-low-risk-laparoscopic-cholecystectomy-is-unnecessary-a-randomized-clinical-trial
#18
RANDOMIZED CONTROLLED TRIAL
Jay Narayan Shah, Shanta Bir Maharjan, Sanjay Paudyal
BACKGROUND: Laparoscopic cholecystectomy uses smaller incision and trocars that lessen the contamination and exposure of wound, resulting in less infection. However, the antibiotic prophylaxis is still widely practiced, like in our institute, a continuation of the era of open surgery. Recent studies reveal no advantage of routine use of antibiotic, and there is growing consensus against it. Besides cost, antibiotic increases emergence of multidrug resistance. Because of the controversies, we conducted this clinical trial...
October 2012: Asian Journal of Surgery
https://www.readbyqxmd.com/read/22476842/laparoscopic-versus-robotic-subtotal-splenectomy-in-hereditary-spherocytosis-potential-advantages-and-limits-of-an-expensive-approach
#19
COMPARATIVE STUDY
Catalin Vasilescu, Oana Stanciulea, Stefan Tudor
BACKGROUND: This study was designed to compare the laparoscopic subtotal splenectomy with the robotic approach in patients with hereditary spherocytosis. METHODS: Thirty-two consecutive subtotal splenectomies by minimal approach in patients with hereditary spherocytosis were analyzed (10 robotic vs. 22 laparoscopic subtotal splenectomies). RESULTS: A significant difference was found for the robotic approach regarding blood loss, vascular dissection duration, and splenic remnant size...
October 2012: Surgical Endoscopy
https://www.readbyqxmd.com/read/22414004/prevalence-pattern-sensitivity-and-resistance-to-antibiotics-of-different-bacteria-isolated-from-port-site-infection-in-low-risk-patients-after-elective-laparoscopic-cholecystectomy-for-symptomatic-cholelithiasis-at-tertiary-care-hospital-of-kashmir
#20
Mohd Altaf Mir, Umar Younus Malik, Hamza Wani, Biant Singh Bali
The aim of this study was to determine specific pattern of port site microbial colonisation, sensitivity and resistance to different antibiotics of bacteria isolated from port site infection (PSI) in low risk patients after elective laparoscopic cholecystectomy in surgical wards at tertiary care hospital of Kashmir. This is a prospective study. The study included 675 consecutive patients of postoperative PSI after elective laparoscopic cholecystectomy for symptomatic cholelithiasis over a period of 12 months...
February 2013: International Wound Journal
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