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Mazen Zaitouna, Bayan Alsaid, Cédric Lebacle, Krystel Nyangoh Timoh, Gérard Benoît, Thomas Bessede
AIMS: Innervation of the pelvic ureter traditionally comes from the pelvic plexus. This innervation is independent: adrenergic and cholinergic. The purpose of this study was to describe more precisely the origin and nature of its innervation (adrenergic, cholinergic, nitrergic, and somatic). METHODS: Six specimens of normal human fetal pelvis (four male and two female) from 20 to 30 weeks gestation were studied. The sections of these fetuses, carried out every 5 µm without interval, were treated with Hematoxylin Eosin (HE), with Masson's trichrome (TriM), immunolabeling of smooth muscle cells with smooth anti-actin, of nerves with anti-S100 protein, anti-tyrosine hydroxylase, anti-VAChT, anti-nNOS, and with anti- peripheral myelin protein 22 (PMP 22)...
February 2017: Neurourology and Urodynamics
Wen-Chen Huang, Shwu-Huey Yang, Jenn-Ming Yang
AIMS: To explore functional changes of pelvic floor muscle (PFM) after successful Perigee procedures. METHODS: We retrospectively analyzed information from 145 women having achieved anatomic success, defined as <stage II cystocele according to the pelvic organ prolapse quantification (POP-Q) system. The investigated data included results from the POP-Q system and four-dimensional ultrasound at the preoperative and 12-month postoperative evaluations. The involuntary and voluntary PFM functions were, respectively, investigated during coughing and squeezing using the ultrasound parameters of the bladder neck distance (BND), bladder neck angle (BNA), genitohiatal distance (GHD), and genitohiatal angle...
February 2017: Neurourology and Urodynamics
Oscar Contreras Ortiz, Diaa Ee Rizk, Gabriele Falconi, Lucas Schreiner, Viridiana Gorbea Chávez
AIM: For four decades, the training for fellows in Urogynecology has been defined by taking into account the proposals of the relevant international societies. Primary health care providers and general OB/GYN practitioners could not find validated guidelines for the integration of knowledge in pelvic floor dysfunctions. The FIGO Working Group (FWG) in Pelvic Floor Medicine and Reconstructive Surgery has looked for the consensus of international opinion leaders in order to develop a set of minimal requirements of knowledge and skills in this area...
February 2017: Neurourology and Urodynamics
Hyun Suk Peter Suh, Hyung Hwa Jeong, Dong Hoon Choi, Joon Pio J P Hong
BACKGROUND: The two major perforators supplying the superficial circumflex iliac artery perforator flap are the medial (superficial) and lateral (deep) perforators; however, they lack detailed description. The purpose of this study was to clarify the anatomy. METHODS: In a prospective analysis of 142 patients, computed tomographic angiograms of 284 superficial circumflex iliac artery perforator regions were evaluated, and 142 superficial circumflex iliac artery perforator flaps were surgically correlated...
March 2017: Plastic and Reconstructive Surgery
Erin Greaves, Hilary O D Critchley, Andrew W Horne, Philippa T K Saunders
Endometriosis is characterised by the growth of endometrial-like tissue outside the uterus, most commonly on the pelvic peritoneum and ovaries. Whilst it may be asymptomatic in some women in others it can cause debilitating pain, infertility or other symptoms including fatigue. Current research is directed both at understanding the complex aetiology and pathophysiology of the disorder and the development of new non-surgical approaches to therapy which lack the unwanted side effects of current medical management...
February 24, 2017: Acta Obstetricia et Gynecologica Scandinavica
A Huertas, S Oldrini, J-P Nesseler, F Courrech, P Rétif, C Charra-Brunaud, D Peiffert
The treatment of cervical cancers according to FIGO staging is well defined. For FIGO stage IB2 or more, chemoradiotherapy followed by uterovaginal brachytherapy boost is the standard treatment. Surgery is the preferred choice for less advanced tumors. However, most French institutions propose preoperative brachytherapy followed by hysterectomy with pelvic lymphadenectomy for FIGO stage IB1 tumors over 2cm. Brachytherapy is also used for the boost after adjuvant pelvic external beam radiotherapy. Tridimensional dosimetry with optimization allows better treatment planning, delivering high doses to target volumes with limited irradiation to the organs at risk...
February 20, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
Kari L Ring, Anna V Yemelyanova, Pamela T Soliman, Michael M Frumovitz, Amir A Jazaeri
OBJECTIVE: Our objective was to characterize the intra and peritumoral immune profile in recurrent cervical cancers to identify rational immunotherapy targets. METHODS: Archival pelvic exenteration specimens were examined using a validated multiplex immuno-fluorescent panel of antibodies against cluster of differentiation 8 (CD8), cluster of differentiation 68 (CD68), forkhead box P3 (FoxP3), programmed cell death protein 1 (PD1), and programmed death-ligand 1 (PD-L1, N=28)...
February 20, 2017: Gynecologic Oncology
Clare McFadden, Marc F Oxenham
The ability to identify whether a female has been pregnant or has given birth has significant implications for forensic investigations and bioarcheological research. The meaning of "scars of parturition," their causes, and their significance are a matter of contention, with a substantial literature of re-evaluations and tests of the relationship between pelvic scarring and parity. The aim of this study was to use meta-analytic techniques (the methodological approach) to test whether pelvic scarring, namely dorsal pubic pitting and the preauricular groove, is a predictor of parity and sex...
February 24, 2017: Journal of Forensic Sciences
Elizabeth Roth, Jessica Goetz, John Kryger, Travis Groth
Surgical repair of bladder exstrophy is an ongoing challenge for pediatric urologists. Postoperative immobilization is a mainstay of care to decrease tension on the repair site and is often utilized in conjunction with pelvic osteotomies performed in the same operative setting by pediatric orthopedic surgeons. Multiple pelvic immobilization techniques have been developed in conjunction with repair techniques including special techniques for neonates. The most commonly utilized techniques for pelvic immobilization are Buck's and Bryant's traction and spica casting...
March 2017: Current Urology Reports
Xing-Wei Jin, Bo-Ke Liu, Xiang Zhang, Zhong-Hua Zhao, Yuan Shao
The aim of this study is to identify whether vaccinating twice with bladder homogenate can establish a new model of experimental autoimmune cystitis (EAC) in C57BL/6 strain mice. C57BL/6 mice were vaccinated with bladder homogenate in complete Freund's adjuvant (CFA) and boost immunized with bladder homogenate in incomplete Freund's adjuvant (IFA) after 2 weeks were used as the EAC model. Mice immunized with phosphate-buffered saline (PBS) in CFA or IFA were used as the control. Micturition habits and suprapubic-pelvic pain threshold were measured 4 weeks after primary immunization...
February 23, 2017: Inflammation
Iva Sklempe Kokic, Marina Ivanisevic, Melita Uremovic, Tomislav Kokic, Rado Pisot, Bostjan Simunic
OBJECTIVE: To investigate the effect of a supervised, structured exercise programme on the occurrence and severity of pregnancy-related lumbopelvic pain. DESIGN: Randomized controlled trial. SUBJECTS: A total of 45 pregnant women were randomly assigned to 2 groups: an experimental group (n = 20; mean age 32.8 (standard deviation (SD) 3.6) years) and a control group (n = 22; mean age 32.2 years (SD 4.9)). METHODS: Exercise intervention for the experimental group consisted of aerobic and resistance exercises performed bi-weekly from the date of inclusion into the study until the end of pregnancy, together with at least 30 min of brisk daily walks...
February 24, 2017: Journal of Rehabilitation Medicine
Heather J Chalfin, Zhaoyong Feng, Bruce J Trock, Alan W Partin
OBJECTIVES: To examine nationwide patterns of lymph node dissection (LND) in men with D'Amico low-risk prostate cancer, including the rate of detected lymph node metastasis and factors associated with the decision to perform LND. Existing guidelines recommend against LND at the time of radical prostatectomy (RP) in low-risk men, yet this is still a common practice. METHODS: The 2013 National Cancer Database includes 1,208,180 cases of prostate cancer diagnosed between 2004-2013...
February 20, 2017: Urology
Erik N Mayer, Sara M Lenherr, Heidi A Hanson, Terry C Jessop, William T Lowrance
OBJECTIVE: To describe the publication productivity of academic urologists in the United States by gender. MATERIALS AND METHODS: Gender inequality is prevalent in most surgical subspecialties, including urology. Despite small numbers of women in academic positions, differences in scholarly impact by gender are relatively unknown. We assembled a list of 1922 academic urologists (1686 male (87.7%), 236 female (12.3%)) at 124 academic institutions throughout the United States as of February 2016...
February 20, 2017: Urology
Mircea Mircean, Angela Monica Ionică, Viorica Mircean, Adriana Györke, Andrei Răzvan Codea, Flaviu Alexandru Tăbăran, Marian Taulescu, Mirabela Oana Dumitrache
Canine dirofilarioses are mosquito-borne zoonotic diseases with a continuous expansion of their geographical distribution, as a consequence of different climatic and ecological factors. Dirofilaria immitis, the aetiological agent of heartworm disease, has gained a major veterinary interest, mainly due to its severe clinical implication. In the last decades, D. repens, despite of being regarded as a less pathogenic species, regained attention due to its recognized zoonotic potential. Romania has been traditionally regarded as a non-endemic country, but recent epidemiological surveys are highlighting the presence of both D...
February 13, 2017: Parasitology International
Mario Franchini, Brunella Zizolfi, Carmela Coppola, Valentino Bergamini, Cecilia Bonin, Giovanni Borsellino, Enrico Busato, Stefania Calabrese, Stefano Calzolari, Gian Piero Fantin, Giovanna Giarrè, Piero Litta, Massimo Luerti, Francesco Paolo Mangino, Gian Luigi Marchino, Maria Antonietta Molinari, Elisa Scatena, Federica Scrimin, Paolo Telloli, Attilio Di Spiezio Sardo
STUDY OBJECTIVE: To describe safety, tolerability, and effectiveness results through minimum 2-year follow-up of Essure inserts. DESIGN: A retrospective multicenter study DESIGN: Classification: Canadian Task Force II2 SETTING: 7 general hospitals and 4 clinical teaching centers in Italy. PATIENTS: A total of 1,968 women, mean age 39.5 years (range 23-48 years) who underwent office hysteroscopic sterilization using Essure between April 1, 2003, and December 30, 2014...
February 13, 2017: Journal of Minimally Invasive Gynecology
Joao Paulo Leonardo-Pinto, Cristina Laguna Benetti-Pinto, Kleber Cursino, Daniela Angerame Yela
OBJECTIVE: To evaluate the effectiveness of dienogest in controlling pain caused by deep infiltrating endometriosis (DIE), its influence on the quality of live (QoL) of women affected by the disease, and the effect of the drug on the volume of endometriotic lesions. STUDY DESIGN: A prospective cohort study including 30 women with a sonographic diagnosis of DIE (intestinal and posterior fornix) treated with dienogest 2mg per day for 12 months. We evaluated the pain symptoms and the volume of the intestinal and posterior fornix lesions before and after 12 months of use of dienogest...
February 15, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Janet S Carpenter, Michael Heit, Chen X Chen, Ryan Stewart, Jennifer Hamner, Kevin L Rand
OBJECTIVES: No postoperative recovery measurement tools have been validated among women undergoing laparoscopic sacrocolpopexy for pelvic organ prolapse, which impedes development and testing of strategies to improve recovery. The purpose of this study was to evaluate the performance of the Postdischarge Surgical Recovery Scale (PSR) as a measure of perceived recovery in laparoscopic sacrocolpopexy patients. METHODS: Women (N = 120) with stage 2 or higher pelvic organ prolapse undergoing laparoscopic sacrocolpopexy completed a 15-minute postoperative survey (days 7, 14, 42, and 90 [each ± 3 days]) which included the 15-item PSR...
March 2017: Female Pelvic Medicine & Reconstructive Surgery
Daniel E Stone, Benjamin J Barenberg, Stephanie D Pickett, Dena E OʼLeary, Lieschen H Quiroz
OBJECTIVE: To analyze the characteristics of providers performing stress urinary incontinence (SUI) and pelvic organ prolapse (POP) procedures in the United States. METHODS: The Centers for Medicare Services public database, released for years 2012 through 2014, was queried for SUI-related and POP-related Healthcare Common Procedure Coding System. Providers were categorized as Female Pelvic Medicine and Reconstructive Surgery (FPMRS) providers and non-FPMRS providers, using a list of FPMRS board-certified providers compiled through the American Board of Medical Subspecialties website...
March 2017: Female Pelvic Medicine & Reconstructive Surgery
Han-Dong Lee, Chang-Hoon Jeon, Nam-Su Chung, Suk-Hyeong Won
OBJECTIVES: Traumatic spinopelvic dissociation separates the spinal column from the pelvis, which usually creates lumbosacral kyphosis. We aimed to examine how the spinopelvic profiles changes after traumatic spinopelvic dissociation, and which are the relevant factors for the sagittal imbalance of the spine. DESIGN: Retrospective analysis. SETTING: Level I trauma center PATIENTS:: Thirty-nine consecutive patients who were diagnosed with traumatic spinopelvic dissociation and had a minimum 2-year radiological follow-up were included...
February 20, 2017: Journal of Orthopaedic Trauma
Rodolfo Milani, Matteo Frigerio, Alice Cola, Carlo Beretta, Federico Spelzini, Stefano Manodoro
BACKGROUND: Uterosacral ligament (USL) suspension is a safe and effective procedure in terms of anatomical, functional, and subjective outcomes for primary surgical treatment of prolapse. OBJECTIVES: There has been a renewed interest toward native tissue prolapse repair by vaginal route because of low cost and lack of mesh-related complications. Uterosacral ligaments are considered safe, effective, and durable as suspending structures for primary surgical repair of the apical compartment...
February 23, 2017: Female Pelvic Medicine & Reconstructive Surgery
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