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https://www.readbyqxmd.com/read/28922063/individual-calibration-of-accelerometers-in-children-and-their-health-related-implications
#1
Lynne M Boddy, Conor Cunningham, Stuart J Fairclough, Marie H Murphy, Gavin Breslin, Lawrence Foweather, Rebecca M Dagger, Lee E F Graves, Nicola D Hopkins, Gareth Stratton
This study compared children's physical activity (PA) levels, the prevalence of children meeting current guidelines of ≥60 minutes of daily moderate to vigorous PA (MVPA), and PA-health associations using individually calibrated (IC) and empirical accelerometer cutpoints. Data from 75 (n = 32 boys) 10-12 year old children were included in this study. Clustered cardiometabolic (CM) risk, directly measured cardiorespiratory fitness (CRF), anthropometric and 7 day accelerometer data were included within analysis...
September 18, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28919587/human-leukocyte-antigen-class-i-and-ii-variants-in-yemeni-patients-with-chronic-renal-failure
#2
Mogahid Yahi'a Nassar, Hassan Abdulwahab Al-Shamahy, Abdullah Saleh Al-Samawi, Nagieb Waza'a Abu Asba, Ibrahiem Husain El-Nono, Haitham Abdulwahab Masood
BACKGROUND: Human leukocyte antigens (HLAs) are found to be significant genetic factors concerning the susceptibility of an individual to certain diseases. OBJECTIVE: To determine the association between variants of class I (A and B) and class II (DRB1) HLA alleles and chronic renal failure (CRF), compared with healthy controls, in Yemen. METHODS: A case-control study in the Urology and Nephrology Center at Al-Thawra University Hospital in Sana'a, Yemen was carried out between January 2013 and December 2015 and included 187 CRF patients, and 194 healthy controls visiting the same center for kidney donation...
September 2017: Iranian Journal of Immunology: IJI
https://www.readbyqxmd.com/read/28917270/cancer-related-fatigue-in-adolescents-and-young-adults-a-systematic-review-of-the-literature
#3
REVIEW
E Nowe, Y Stöbel-Richter, A Sender, K Leuteritz, M Friedrich, K Geue
Adolescents and young adults with cancer (AYA) represent a specific age cohort dealing with the disease in a stage of life characterized by development, upheavals, and establishment. The aim of this study was to point out the state of research on how AYA are affected by cancer-related fatigue (CRF). RESULTS: Twelve articles were included. CRF was found to be higher in AYA than in either of the comparison groups, healthy peers and older cancer patients. Most included studies did not measure CRF with multidimensional, fatigue-specific instruments...
October 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/28916300/distinct-neuronal-populations-in-the-basolateral-and-central-amygdala-are-activated-with-acute-pain-conditioned-fear-and-fear-conditioned-analgesia
#4
Ryan K Butler, Sarah Ehling, Megan Barbar, Jess Thomas, Mary A Hughes, Charles E Smith, Vladimir M Pogorelov, Dipendra K Aryal, William C Wetsel, B Duncan X Lascelles
Fear-conditioned analgesia (FCA) is modulated by brain areas involved in the descending inhibitory pain pathway such as the basolateral (BLA) and central amygdala (CEA). The BLA contains Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and parvalbumin (PV) neurons. CEA neurons are primarily inhibitory (GABAergic) that comprise enkephalin (ENK) interneurons and corticotropin-releasing factor (CRF) - neurons that project to the periaqueductal grey. The purpose of our experiment was to determine the pattern of activation of CaMKII/PV and ENK/CRF neurons following the expression of acute pain, conditioned fear, and FCA...
September 12, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28916137/oxytocin-induces-penile-erection-and-yawning-when-injected-into-the-bed-nucleus-of-the-stria-terminalis-involvement-of-glutamic-acid-dopamine-and-nitric-oxide
#5
Fabrizio Sanna, Jessica Bratzu, Antonio Argiolas, Maria Rosaria Melis
Oxytocin (5-100ng), but not Arg(8)-vasopressin (100ng), injected unilaterally into the bed nucleus of the stria terminalis (BNST) induces penile erection and yawning in a dose-dependent manner in male rats. The minimal effective dose was 20ng for penile erection and 5ng for yawning. Oxytocin responses were abolished not only by the oxytocin receptor antagonist d(CH2)5Tyr(Me)(2)-Orn(8)-vasotocin (1μg), but also by (+) MK-801 (1μg), an excitatory amino acid receptor antagonist of the N-methyl-d-aspartic acid (NMDA) subtype, SCH 23390 (1μg), a D1 receptor antagonist, but not haloperidol (1μg), a D2 receptor antagonist, and SMTC (40μg), an inhibitor of neuronal nitric oxide synthase, injected into the BNST 15min before oxytocin...
September 12, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/28915823/patients-with-acute-poisoning-presenting-to-an-urban-emergency-department-of-a-tertiary-hospital-in-tanzania
#6
Ghaniya S Mbarouk, Hendry R Sawe, Juma A Mfinanga, John Stein, Shankar Levin, Victor Mwafongo, Michael S Runyon, Teri A Reynolds, Kent R Olson
BACKGROUND: Poisoning is a major public health concern in sub-Saharan Africa, affecting patients of all age groups. Poisoned patients often present to the emergency department (ED) and prompt evaluation and appropriate management are imperative to ensure optimal outcomes. Unfortunately, little is known about the specific presentations of poisoned patients in East Africa. We describe the clinical and epidemiological features of patients presenting to the Muhimbili National Hospital (MNH) ED with suspected toxicological syndromes...
September 16, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28912129/the-efficacy-of-unsupervised-home-based-exercise-regimens-in-comparison-to-supervised-laboratory-based-exercise-training-upon-cardio-respiratory-health-facets
#7
James Blackwell, Philip J Atherton, Kenneth Smith, Brett Doleman, John P Williams, Jonathan N Lund, Bethan E Phillips
Supervised high-intensity interval training (HIIT) can rapidly improve cardiorespiratory fitness (CRF). However, the effectiveness of time-efficient unsupervised home-based interventions is unknown. Eighteen volunteers completed either: laboratory-HIIT (L-HIIT); home-HIIT (H-HIIT) or home-isometric hand-grip training (H-IHGT). CRF improved significantly in L-HIIT and H-HIIT groups, with blood pressure improvements in the H-IHGT group only. H-HIIT offers a practical, time-efficient exercise mode to improve CRF, away from the laboratory environment...
September 2017: Physiological Reports
https://www.readbyqxmd.com/read/28906485/weight-status-cardiorespiratory-fitness-and-high-blood-pressure-relationship-among-5-12-year-old-chinese-primary-school-children
#8
W J Liu, L H Xiong, C S Guo, B Li, M Pallan, T Griffin, K K Cheng, P Adab
Cardiorespiratory fitness (CRF) and adiposity contribute to high blood pressure (HBP) in adults and children. However, their relative importance as risk factors is unknown. We examined the relationships between weight status, CRF and HBP among Chinese primary school children. A cross-sectional study was conducted with 4926 school children aged 5-12 years. CRF was estimated from a modified Cooper test, body mass index z-scores and weight categories were calculated from objective height and weight measurements and BP was measured using an electronic sphygmomanometer...
September 14, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28900818/the-effects-of-chronic-aerobic-exercise-on-cardiovascular-risk-factors-in-persons-with-diabetes-mellitus
#9
REVIEW
Emily M Miele, Samuel A E Headley
PURPOSE OF REVIEW: Aerobic exercise training is a component of diabetes mellitus (DM) care guidelines due to its favorable effects on glycemic control and cardiovascular disease (CVD) risk factors. The purpose of this review is to outline the recent evidence regarding the clinical effects of chronic aerobic exercise on CVD risk factors in persons with DM and to compare the effects of varying intensities and types of exercise. RECENT FINDINGS: Among individuals with DM, all types of aerobic exercise training can impact positively on some traditional and non-traditional risk factors for CVD...
September 12, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28899655/characteristics-of-physical-activity-interventions-and-effects-on-cardiorespiratory-fitness-in-children-aged-6-12-years-a-systematic-review
#10
REVIEW
Petra Braaksma, Ilse Stuive, Rianne M E Garst, Carlijn F Wesselink, Corry K van der Sluis, Rienk Dekker, Marina M Schoemaker
OBJECTIVES: To examine the characteristics of physical activity (PA) interventions and the effects on cardiorespiratory fitness (CRF) in healthy children based on treatment theory. DESIGN: Systematic review. METHODS: PubMed and Embase were searched for studies published between 2003 and 2016. Inclusion criteria were: Participants: healthy children aged 6-12. INTERVENTIONS: interventions with activities to increase PA behaviour or physical fitness (PF) regardless of setting...
July 20, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28898648/motor-control-crf-regulates-coordination-and-gait
#11
Mario Manto
The function of the olivo-cerebellar tract is not restricted to the supervision of plasticity in the cerebellar cortex. There is growing evidence that the climbing fibers also tune motor commands. A novel study unravels a role of corticotropin-releasing factor (CRF) in motor coordination and gait control.
September 11, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28891725/age-related-change-in-corneal-biomechanical-parameters-in-a-healthy-caucasian-population
#12
Ali Riza Cenk Celebi, Ayse Ebru Kilavuzoglu, Ugur Emrah Altiparmak, C Banu Cosar Yurteri
PURPOSE: To determine the effect of aging on corneal biomechanical parameters measured via ocular response analyzer in a homogenous healthy Caucasian population. METHODS: A total of 2039 Caucasian adults were consecutively recruited and divided into seven groups according to decades of age. The difference in mean corneal hysteresis (CH), mean corneal resistance factor (CRF), mean Goldmann-correlated intraocular pressure (IOPg), and mean corneal-compensated IOP (IOPcc) between decades of age were investigated...
September 11, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28889367/identifying-the-subtypes-of-cancer-related-fatigue-results-from-the-population-based-profiles-registry
#13
Melissa S Y Thong, Floortje Mols, Lonneke V van de Poll-Franse, Mirjam A G Sprangers, Carin C D van der Rijt, Andrea M Barsevick, Hans Knoop, Olga Husson
PURPOSE: Little research has been done to identify possible cancer-related fatigue (CRF) subtypes and to classify cancer survivors accordingly. We aimed to identify CRF subtypes in a large population-based sample of (long term) stage I-III colorectal cancer survivors. We also identified factors associated with the CRF subtypes. METHODS: Respondents completed the Multidimensional Fatigue Inventory and other validated questionnaires on anxiety and reduced positive affect (anhedonia), sleep quality, and lifestyle factors (body mass index and physical activity)...
September 9, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/28887088/impact-of-the-heart-rate-on-the-shape-of-the-cardiac-response-function
#14
Feliberto de la Cruz, Andy Schumann, Stefanie Köhler, Karl-Jürgen Bär, Gerd Wagner
There is limited understanding about how heart rate (HR) influences the blood-oxygen level dependent (BOLD) signal. While the mechanism by which respiration induces fluctuation in the BOLD signal is relatively well understood, the mechanisms regarding the HR remains unclear. The application of canonical cardiac response function (CRF), or subject-specific CRF, is an effective method for creating nuisance regressors, which can be used to remove cardiac-induced fluctuations in the BOLD signal. However, the relationship between physiological parameters and the characteristics of the CRF has not been systematically investigated...
September 5, 2017: NeuroImage
https://www.readbyqxmd.com/read/28887029/urocortins-actions-in-health-and-heart-failure
#15
REVIEW
Miriam T Rademaker, A Mark Richards
The urocortins (Ucns), endogenous peptides belonging to the corticotropin-releasing factor (CRF) family, are increasingly recognized as having diverse and important multi-system functions, especially within the cardiovascular system. The biological actions of the three Ucns (Ucn1, Ucn2, Ucn3) are mediated via G-protein-coupled CRF receptors, with both peptides and receptors widely distributed throughout tissues and organs contributing to pressure/volume homeostasis including the heart, vasculature, kidneys and adrenals...
September 5, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28885263/the-use-of-methylphenidate-to-relieve-fatigue
#16
Rocío Rojí, Carlos Centeno
PURPOSE OF REVIEW: To review recent evidence on the efficacy and safety of methylphenidate as a symptomatic treatment of patients with cancer-related fatigue (CRF). RECENT FINDINGS: Five clinical trials published since 2011 were identified. Two of these concluded that methylphenidate is more efficacious than placebo in providing relief from CRF, but the remaining three showed no difference in favour of methylphenidate. The studies were heterogeneous as per the dosage, scales used for evaluating fatigue and the target group studied...
September 6, 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/28882466/a-low-degree-of-high-ambient-temperature-decreased-food-intake-and-activated-median-preoptic-and-arcuate-nuclei
#17
Pornsiri Suwanapaporn, Narongsak Chaiyabutr, Sumpun Thammacharoen
High ambient temperature (HTa) activates both behavioral and autonomic responses. Decreased food intake (FI) is a well-known behavioral response under HTa. In general, this behavioral response seems to be mediated under the activation of the stress axis. The present study, however, revealed that decreased FI after a low degree of HTa appeared to be activated earlier than stress axis activation. By comparing low and high levels of HTa exposure in rats, the present experiment demonstrated that the HTa-induced decrease in FI was clear in both conditions...
September 4, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28882338/relationship-of-cardiorespiratory-fitness-and-adiposity-with-left-ventricular-strain-in-middle-age-adults-from-the-dallas-heart-study
#18
Ambarish Pandey, Bryan Park, Spencer Martens, Colby Ayers, Ian J Neeland, Mark J Haykowsky, Michael D Nelson, Satyam Sarma, Jarett D Berry
Low cardiorespiratory fitness (CRF) and obesity are significant risk factors for heart failure (HF). However, given the inverse association between CRF and obesity, the independent contributions of low CRF and adiposity toward HF risk are not well established. We evaluated the association of CRF and measures of adiposity with left ventricular (LV) peak systolic strain-a subclinical measure of LV dysfunction-among the Dallas Heart Study phase II participants without cardiovascular disease who had CRF estimated using a submaximal treadmill test and LV systolic circumferential strain assessment by tissue-tagged cardiac magnetic resonance imaging...
July 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28881963/deep-learning-with-word-embeddings-improves-biomedical-named-entity-recognition
#19
Maryam Habibi, Leon Weber, Mariana Neves, David Luis Wiegandt, Ulf Leser
Motivation: Text mining has become an important tool for biomedical research. The most fundamental text-mining task is the recognition of biomedical named entities (NER), such as genes, chemicals and diseases. Current NER methods rely on pre-defined features which try to capture the specific surface properties of entity types, properties of the typical local context, background knowledge, and linguistic information. State-of-the-art tools are entity-specific, as dictionaries and empirically optimal feature sets differ between entity types, which makes their development costly...
July 15, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28881147/cardiorespiratory-demand-of-acute-voluntary-cycling-with-functional-electrical-stimulation-in-individuals-with-multiple-sclerosis-with-severe-mobility-impairment
#20
Thomas Edwards, Robert W Motl, Lara A Pilutti
BACKGROUND: Exercise training is one strategy for improving cardiorespiratory fitness (CRF) in multiple sclerosis (MS), however, few modalities are accessible for those with severe mobility impairment. Functional electrical stimulation (FES) cycling is one adapted exercise modality with the potential for improving CRF in people with severe MS. OBJECTIVES: To characterize the cardiorespiratory response of acute voluntary cycling with FES in people with MS with severe mobility impairment, and to compare this response to passive leg cycling...
September 7, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
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