keyword
MENU ▼
Read by QxMD icon Read
search

CRF

keyword
https://www.readbyqxmd.com/read/29150162/distribution-of-clinical-risk-factors-for-fracture-in-a-brussels-cohort-of-postmenopausal-women-the-frisbee-study-and-comparison-with-other-major-cohort-studies
#1
S I Cappelle, I Ramon, C Dekelver, S Rozenberg, F Baleanu, R Karmali, M Rubinstein, M Tondeur, M Moreau, M Paesmans, P Bergmann, J-J Body
OBJECTIVES: The estimation of fracture risk using clinical risk factors (CRFs) is of primary concern in osteoporosis management, but only some risk factors have been thoroughly evaluated and incorporated in predictive models. We have launched a large prospective study, the 'Fracture Risk Brussels Epidemiological Enquiry' (FRISBEE), to develop a new predictive model for osteoporotic fractures. The aims of this report are to describe the methodology of the FRISBEE study and to compare the distribution of CRFs in our cohort with those reported in other large studies...
December 2017: Maturitas
https://www.readbyqxmd.com/read/29149217/per-service-supervised-learning-for-identifying-desired-wot-apps-from-user-requests-in-natural-language
#2
Young Yoon
Web of Things (WoT) platforms are growing fast so as the needs for composing WoT apps more easily and efficiently. We have recently commenced the campaign to develop an interface where users can issue requests for WoT apps entirely in natural language. This requires an effort to build a system that can learn to identify relevant WoT functions that fulfill user's requests. In our preceding work, we trained a supervised learning system with thousands of publicly-available IFTTT app recipes based on conditional random fields (CRF)...
2017: PloS One
https://www.readbyqxmd.com/read/29146561/recurrent-neural-networks-with-specialized-word-embeddings-for-health-domain-named-entity-recognition
#3
Iñigo Jauregi Unanue, Ehsan Zare Borzeshi, Massimo Piccardi
BACKGROUND: Previous state-of-the-art systems on Drug Name Recognition (DNR) and Clinical Concept Extraction (CCE) have focused on a combination of text "feature engineering" and conventional machine learning algorithms such as conditional random fields and support vector machines. However, developing good features is inherently heavily time-consuming. Conversely, more modern machine learning approaches such as recurrent neural networks (RNNs) have proved capable of automatically learning effective features from either random assignments or automated word "embeddings"...
November 13, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29146239/innately-activated-tlr4-signal-in-the-nucleus-accumbens-is-sustained-by-crf-amplification-loop-and-regulates-impulsivity
#4
Irina Balan, Kaitlin T Warnock, Adam Puche, Marjorie C Gondre-Lewis, Laure Aurelian
Cognitive impulsivity is a heritable trait believed to represent the behavior that defines the volition to initiate alcohol drinking. We have previously shown that a neuronal Toll-like receptor 4 (TLR4) signal located in the central amygdala (CeA) and ventral tegmental area (VTA) controls the initiation of binge drinking in alcohol-preferring P rats, and TLR4 expression is upregulated by alcohol-induced corticotropin-releasing factor (CRF) at these sites. However, the function of the TLR4 signal in the nucleus accumbens shell (NAc-shell), a site implicated in the control of reward, drug-seeking behavior and impulsivity and the contribution of other signal-associated genes, are still poorly understood...
November 13, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29139007/adding-high-intensity-interval-training-to-conventional-training-modalities-optimizing-health-related-outcomes-during-chemotherapy-for-breast-cancer-the-optitrain-randomized-controlled-trial
#5
Sara Mijwel, Malin Backman, Kate A Bolam, Anna Jervaeus, Carl Johan Sundberg, Sara Margolin, Maria Browall, Helene Rundqvist, Yvonne Wengström
PURPOSE: Exercise training is an effective and safe way to counteract cancer-related fatigue (CRF) and to improve health-related quality of life (HRQoL). High-intensity interval training has proven beneficial for the health of clinical populations. The aim of this randomized controlled trial was to compare the effects of resistance and high-intensity interval training (RT-HIIT), and moderate-intensity aerobic and high-intensity interval training (AT-HIIT) to usual care (UC) in women with breast cancer undergoing chemotherapy...
November 14, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29138633/influence-of-spk-with-enteric-drainage-on-the-pancreatic-exocrine-function-in-diabetic-patients-with-uremia
#6
Guanghui Pei, Wu Lv, Xiaohang Li, Guoqing Zhang, Jialin Zhang
Objective: This study aimed to determine the use of fecal elastase in evaluating the effect of simultaneous pancreas-kidney transplantation with enteric drainage on the pancreatic exocrine function of diabetic patients with uremia. Methods: A total of 19 patients with simultaneous pancreas-kidney transplantation (SPK) with enteric drainage, 31 diabetic patients with uremia (chronic renal failure (CRF)), 22 diabetic patients with uremia who underwent renal transplantation (RT), and 20 normal individuals (CON) were included in the study...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/29135784/fitness-fatness-physical-activity-and-autonomic-function-in-midlife
#7
Antti M Kiviniemi, Nelli Perkiömäki, Juha Auvinen, Maisa Niemelä, Tuija Tammelin, Katri Puukka, Aimo Ruokonen, Sirkka Keinänen-Kiukaanniemi, Mikko P Tulppo, Marjo-Riitta Järvelin, Timo Jämsä, Heikki V Huikuri, Raija Korpelainen
PURPOSE: Although low cardiorespiratory fitness (CRF), physical inactivity, and obesity are associated with impaired autonomic function, they are also extensively interrelated. The present study aimed to assess the extent to which they contribute to autonomic function independently of each other. METHODS: At the age of 46 yr, 1383 men and 1761 women without cardiorespiratory diseases and diabetes underwent assessments of vagally mediated heart rate (HR) variability (root mean square of successive differences in R-R interval (rMMSD)), peak HR during a submaximal step test (CRF), and 60-s HR recovery (HRR)...
December 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29134506/the-risk-of-eating-disorders-and-bone-health-in-young-adults-the-mediating-role-of-body-composition-and-fitness
#8
Miriam Garrido-Miguel, Ana Torres-Costoso, María Martínez-Andrés, Blanca Notario-Pacheco, Ana Díez-Fernández, Celia Álvarez-Bueno, Jorge Cañete García-Prieto, Vicente Martínez-Vizcaíno
PURPOSE: To analyze the independent relationship between the risk of eating disorders and bone health and to examine whether this relationship is mediated by body composition and cardiorespiratory fitness (CRF). METHODS: In this cross-sectional study, bone-related variables, lean mass, fat mass (by DXA), risk of eating disorders (SCOFF questionnaire), height, weight, waist circumference and CRF were measured in 487 university students aged 18-30 years from the University of Castilla-La Mancha, Spain...
November 13, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/29128952/effects-of-acupuncture-on-cancer-related-fatigue-a-meta-analysis
#9
REVIEW
Yan Zhang, Lu Lin, Huiling Li, Yan Hu, Li Tian
PURPOSE: This study was designed to critically evaluate the effect of acupuncture on cancer-related fatigue (CRF). METHODS: Seven databases (Cochrane Library, Embase, Medline, Web of Science, CBM, Wanfang, and CNKI) were systematically reviewed from inception to November 2016 for randomized controlled trials (RCTs). Two reviewers critically and independently assessed the risk of bias using Cochrane Collaboration criteria and extracted correlated data using the designed form...
November 11, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29127575/bright-light-therapy-improves-cancer-related-fatigue-in-cancer-survivors-a-randomized-controlled-trial
#10
Jillian A Johnson, Sheila N Garland, Linda E Carlson, Josée Savard, J Steven A Simpson, Sonia Ancoli-Israel, Tavis S Campbell
PURPOSE: Cancer-related fatigue (CRF) is a common and distressing symptom that can persist after cancer treatment has concluded. Bright light therapy has shown preliminary efficacy in reducing CRF, but its impact on other psychosocial factors is unclear. The purpose was to examine the impact of a 1-month light therapy intervention on fatigue, mood, and quality of life in cancer survivors with fatigue. METHODS: This 4-week blinded randomized controlled trial recruited cancer survivors who met diagnostic criteria for CRF...
November 10, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29127475/associations-between-the-adherence-to-the-mediterranean-diet-and-cardiorespiratory-fitness-with-total-and-central-obesity-in-preschool-children-the-prefit-project
#11
Idoia Labayen Goñi, Lide Arenaza, María Medrano, Natalia García, Cristina Cadenas-Sanchez, Francisco B Ortega
PURPOSE: Early recognition of risk factors associated with overweight/obesity is an important step towards preventing long-term health consequences. The aim of the current study was to examine the associations of the adherence to the Mediterranean dietary pattern (MDP) and cardiorespiratory fitness (CRF) with adiposity in preschool children from the north of Spain. METHODS: The adherence to the MDP (KIDMED), CRF (20-m shuttle run test), total (BMI) and central (waist circumference) adiposity and socio-demographic factors were assessed in 619 children (48...
November 10, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/29124731/cardiovascular-risk-burden-and-future-risk-of-walking-speed-limitation-in-older-adults
#12
Emerald G Heiland, Chengxuan Qiu, Rui Wang, Giola Santoni, Yajun Liang, Laura Fratiglioni, Anna-Karin Welmer
OBJECTIVES: To explore the association between cardiovascular risk factor (CRF) burden and limitation in walking speed, balance, and chair stand and to verify whether these associations vary according to age and cognitive status. DESIGN: Longitudinal population-based study. SETTING: Urban area of Stockholm, Sweden. PARTICIPANTS: Individuals aged 60 and older who participated in the Swedish National Study on Aging and Care in Kungsholmen and were free of limitations in walking speed (n = 1,441), balance (n = 1,154), or chair stands (n = 1,496) at baseline (2001-04)...
November 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29122618/effects-of-tai-chi-exercise-on-cancer-related-fatigue-in-patients-with-nasopharyngeal-carcinoma-undergoing-chemoradiotherapy-a-randomized-controlled-trial
#13
Wei Zhou, Yong-Hui Wan, Qian Chen, Yan-Ru Qiu, Xiao-Min Luo
CONTEXT: Tai Chi exercise has been shown to improve cancer-related fatigue (CRF) and autonomic nervous system (ANS) balance in some cancer patients or survivors, however, such effects are yet to be verified in nasopharyngeal carcinoma (NPC) patients undergoing chemoradiotherapy. OBJECTIVES: To explore the effects of Tai Chi exercise on CRF in NPC patients undergoing chemoradiotherapy and then to evaluate ANS information indicated by heart rate variability (HRV) parameters and their association with CRF...
November 6, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29121414/stress-induced-suppression-of-neuropeptide-y-induced-hunger-in-anorexic-chicks-involves-corticotropin-releasing-factor-signaling-and-the-paraventricular-nucleus-of-the-hypothalamus
#14
Jinxin Wang, Jiaqing Yi, Paul B Siegel, Mark A Cline, Elizabeth R Gilbert
The Virginia lines of chickens have been selected for low (LWS) or high (HWS) juvenile body weight and have different severities of anorexia and obesity, respectively. The LWS that are exposed to stressors at hatch are refractory to neuropeptide Y (NPY)-induced food intake and the objective was to elucidate the underlying mechanisms. Chicks were exposed to a stressor (-20°C for 6 minutes, and 22°C and delayed access to food for 24 hours) after hatch and hypothalamic nuclei, including the lateral hypothalamus (LH), paraventricular nucleus (PVN), ventromedial hypothalamus (VMH), and arcuate nucleus (ARC), were collected 5 days later...
November 9, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/29118713/corticotropin-releasing-factor-in-the-bed-nucleus-of-the-stria-terminalis-in-socially-defeated-and-non-stressed-mice-with-a-history-of-chronic-alcohol-intake
#15
Lucas Albrechet-Souza, Thiago W Viola, Rodrigo Grassi-Oliveira, Klaus A Miczek, Rosa M M de Almeida
Stress exposure has been identified as one risk factor for alcohol abuse that may facilitate the transition from social or regulated use to the development of alcohol dependence. Preclinical studies have shown that dysregulation of the corticotropin releasing factor (CRF) neurotransmission has been implicated in stress-related psychopathologies such as depression and anxiety, and may affect alcohol consumption. The bed nucleus of the stria terminalis (BNST) contains CRF-producing neurons which seem to be sensitive to stress...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29115460/activation-of-corticotropin-releasing-factor-receptor-1-aggravates-dextran-sodium-sulphate-induced-colitis-in-mice-by-promoting-m1-macrophage-polarization
#16
Hong Chen, Haitao Shi, Yaping Liu, Xiaoyang Ren, Shuixiang He, Xinming Chang, Yan Yin
The corticotropin-releasing factor (CRF) family is involved in modulating gastrointestinal motility, sensitivity and inflammation. CRF signalling exerts an important role in inflammatory bowel disease (IBD), predominantly by activating CRF receptors. The aim of the present study was to investigate the function of CRF receptor 1 (CRF‑R1) in the development of mucosal inflammation induced by dextran sulphate sodium (DSS) and the underlying mechanism. Consecutive administration of CRF or CP154526 was used to activate or block the CRF‑R1 in DSS‑treated mice...
October 26, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29115406/berberine-prevents-the-apoptosis-of-mouse-podocytes-induced-by-traf5-overexpression-by-suppressing-nf-%C3%AE%C2%BAb-activation
#17
Feng Wu, Dong-Sheng Yao, Tian-Ying Lan, Chen Wang, Jian-Dong Gao, Li-Qun He, Di Huang
Berberine (BBR) has previously been found to exert beneficial effects on renal injury in experimental rats. However, the mechanisms underlying these effects are not yet fully understood. Tumor necrosis factor (TNF) receptor-associated factor 5 (TRAF5) has been demonstrated to mediate the activation of nuclear factor-κB (NF-κB), which has been implicated in the pathogenesis of chronic kidney disease (CKD). The aim of this study was to investigate the effects of BBR on kidney injury and the activation of the NF-κB signaling pathway in mouse podocytes...
November 7, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29110932/dengue-vaccine-supplies-under-endemic-and-epidemic-conditions-in-three-dengue-endemic-countries-colombia-thailand-and-vietnam
#18
Jung-Seok Lee, Jacqueline K Lim, Duc Anh Dang, Thi Hien Anh Nguyen, Andrew Farlow
BACKGROUND: Dengue fever has been a major public health concern in Colombia, Thailand, and Vietnam. Unlike other infectious diseases, dengue vaccines had not been available for a long time, causing difficulties to control the disease. However, the first live attenuated, tetravalent dengue vaccine (CYD-TDV) became available in 2016 and has been already licensed in some dengue-endemic countries. Because several second-generation dengue vaccines are also in the pipeline, it is critical to understand the efficient allocation of dengue vaccines considering the geographical variation of the disease...
October 27, 2017: Vaccine
https://www.readbyqxmd.com/read/29104870/age-related-variations-of-rabbit-corneal-geometrical-and-clinical-biomechanical-parameters
#19
Haixia Zhang, Xiao Qin, Xiaomeng Cao, Di Zhang, Lin Li
Purpose: To study the variations in corneal clinical biomechanical parameters (CCBP) and corneal geometrical parameters of rabbit in relation to age. Methods: Rabbits aged 3, 7, 12, 18, and 24 months were enrolled. Each eye of the rabbits was tested with Ocular Response Analyzer (ORA), Optical Coherence Tomography (OCT), and Pachymeter to obtain the intraocular pressure (IOP): Goldmann-correlated IOP (IOPg) and Corneal Compensated Intraocular Pressure (IOPcc); CCBP: Corneal Hysteresis (CH) and Corneal Resistance Factor (CRF); corneal geometric parameters: corneal curvature radius (CCR) and central corneal thickness (CCT)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29103148/cerebrovascular-co2-reactivity-during-isoflurane-nitrous-oxide-anesthesia-in-patients-with-chronic-renal-failure
#20
Kazuyoshi Ishida, Masato Uchida, Kohji Utada, Atsuo Yamashita, Satoshi Yamashita, Shiro Fukuda, Mishiya Matsumoto, Takefumi Sakabe
PURPOSE: We assessed the cerebrovascular CO2 reactivity (CO2R) in chronic renal failure (CRF) patients without diabetes mellitus (DM), uncontrolled hypertension, peripheral vascular disease, or neurological disease under isoflurane-nitrous oxide anesthesia. METHODS: Forty-nine patients undergoing surgery, including 36 CRF patients (30 receiving dialysis and six pre-dialysis patients) and 13 patients without CRF (controls). Middle cerebral artery flow velocity (VMCA) was measured by transcranial Doppler ultrasonography at an end-tidal CO2 of 35 to 45 mmHg...
November 4, 2017: Journal of Anesthesia
keyword
keyword
13826
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"