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Ureteral injury

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https://www.readbyqxmd.com/read/28225832/elevated-bilirubin-levels-are-associated-with-a-better-renal-prognosis-and-ameliorate-kidney-fibrosis
#1
Sehoon Park, Do Hyoung Kim, Jin Ho Hwang, Yong-Chul Kim, Jin Hyuk Kim, Chun Soo Lim, Yon Su Kim, Seung Hee Yang, Jung Pyo Lee
BACKGROUND: Bilirubin has been reported to protect against kidney injury. However, further studies highlighting the beneficial effects of bilirubin on renal fibrosis and chronic renal function decline are necessary. METHODS: We assessed a prospective cohort with a reference range of total bilirubin levels. The primary outcome was a 30% reduction in the estimated glomerular filtration rate (eGFR) from baseline, and the secondary outcome was a doubling of the serum creatinine levels, halving of the eGFR and the initiation of dialysis...
2017: PloS One
https://www.readbyqxmd.com/read/28220032/pharmacologic-blockade-of-%C3%AE-v%C3%AE-1-integrin-ameliorates-renal-failure-and-fibrosis-in-vivo
#2
Yongen Chang, Wei Ling Lau, Hyunil Jo, Kazuyuki Tsujino, Leslie Gewin, Nilgun Isik Reed, Amha Atakilit, Ane Claudia Fernandes Nunes, William F DeGrado, Dean Sheppard
Activated fibroblasts are deemed the main executors of organ fibrosis. However, regulation of the pathologic functions of these cells in vivo is poorly understood. PDGF receptor β (PDGFRβ) is highly expressed in activated pericytes, a main source of fibroblasts. Studies using a PDGFRβ promoter-driven Cre system to delete αv integrins in activated fibroblasts identified these integrins as core regulators of fibroblast activity across solid organs, including the kidneys. Here, we used the same PDGFRβ-Cre line to isolate and study renal fibroblasts ex vivo We found that renal fibroblasts express three αv integrins, namely αvβ1, αvβ3, and αvβ5...
February 20, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28216920/posthysterectomy-ureteric-injuries-presentation-and-outcome-of-management
#3
S B Patil, Nilesh Guru, V S Kundargi, B S Patil, Nikhil Patil, Kshitiz Ranka
PURPOSE: The purpose of the study was to evaluate the presentation and management of posthysterectomy ureteral injuries. PATIENTS AND METHODS: Fourteen patients with ureteric injuries after hysterectomy for benign diseases were evaluated. The diagnosis was done based on clinical presentation, intravenous urogram, computed tomography, cystoscopy, and retrograde pyelogram (RGP) depending on the clinical situation. RESULTS: Sixteen iatrogenic ureteric injuries in 14 patients over a 2-year period were evaluated...
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28209495/maternal-obesity-and-major-intraoperative-complications-during-cesarean-delivery
#4
Marcela C Smid, Catherine J Vladutiu, Sarah K Dotters-Katz, Kim A Boggess, Tracy A Manuck, David M Stamilio
BACKGROUND: Multiple studies have demonstrated an association between maternal obesity and postoperative complications, but there is a dearth of information about the impact of obesity on intraoperative complications. OBJECTIVE: To estimate the association between maternal obesity at delivery and major intraoperative complications during cesarean delivery (CD). METHODS: This is a secondary analysis of the de-identified MFMU Cesarean Registry of women with singleton pregnancies...
February 13, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28202301/preoperative-assessment-of-the-ureter-with-dual-phase-contrast-enhanced-computed-tomography-for-lateral-lumbar-interbody-fusion-procedures
#5
Shunsuke Fujibayashi, Bungo Otsuki, Hiroaki Kimura, Shimei Tanida, Kazutaka Masamoto, Shuichi Matsuda
BACKGROUND: Performing the minimally invasive lateral lumbar interbody fusion (LIF), such as the extreme lateral interbody fusion (XLIF) and oblique lateral interbody fusion (OLIF), through a retroperitoneal approach has become increasingly popular. Although urological injury is a major complication of LIF, the anatomical location of the ureter and its risk of injury have not been assessed. The purpose of this study was to evaluate the efficacy of dual-phase contrast-enhanced computed tomography for assessing the location of the ureter and risk of its injury in consecutive LIF cases...
February 12, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28191789/attenuation-of-partial-unilateral-ureteral-obstruction-induced-renal-damage-with-hyperbaric-oxygen-therapy-in-a-rat-model
#6
Eyup Burak Sancak, Yusuf Ziya Tan, Hakan Turkon, Coskun Silan
OBJECTIVE: The objective of the present study was to evaluate the effectiveness of HBO therapy on biochemical parameters, renal morphology and renal scintigraphy in rats undergoing chronic unilateral partial ureteral obstruction (UPUO). MATERIAL AND METHODS: Thirty-five rats were divided into five equal groups: Control group; Sham group; HBO group; UPUO group and UPUO/HBO group. The effects of HBO therapy were examined using biochemical parameters and histopathological changes...
January 27, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28188468/transvaginal-uterosacral-ligament-suspension-for-posthysterectomy-vaginal-vault-prolapse-repair
#7
Rodolfo Milani, Matteo Frigerio, Federico Spelzini, Stefano Manodoro
INTRODUCTION AND HYPOTHESIS: Posthysterectomy vaginal vault prolapse repair represents a challenge for urogynecologists. Surgical management can be successfully achieved with native tissue using a vaginal approach with uterosacral ligament (USL) suspension. However, severe complications have been described, mainly related to ureteral injury. METHODS: A 57-year-old woman with symptomatic stage 2 vaginal vault prolapse underwent transvaginal USL suspension according to the described technique...
February 10, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28164127/renal-expression-and-urinary-excretion-of-na-k-2cl-cotransporter-in-obstructive-nephropathy
#8
Anabel Brandoni, Adriana M Torres
Renal damage due to urinary tract obstruction accounts for up to 30% of acute kidney injury in paediatrics and adults. Bilateral ureteral obstruction (BUO) is associated with polyuria and reduced urinary concentrating capacity. We investigated the renal handling of water and electrolytes together with the renal expression and the urinary excretion of the Na-K-Cl cotransporter (NKCC2) after 1 (BUO-1), 2 (BUO-2), and 7 (BUO-7) days of release of BUO. Immunoblotting and immunohistochemical studies showed that NKCC2 expression was upregulated in apical membranes both from BUO-2 and from BUO-7 rats...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28160521/urologic-injuries-during-gynecologic-surgery-a-10-year-review
#9
Sikarn Satitniramai, Jittima Manonai
AIMS: The study was conducted to evaluate the incidence of urologic injuries during gynecologic surgery, study the management and outcome of such injuries, and identify risk factors that may be associated with urologic injuries. METHODS: A case-control study was conducted in patients who underwent gynecologic surgery from 2005 to 2014 in the university hospital. The study cases referred to patients who had urologic injury during gynecologic surgery and the control cases referred to patients who had gynecologic surgery matching the same period, type of procedure, and etiological disease leading to surgery...
February 4, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28159465/a-comparison-of-sentinel-lymph-node-biopsy-to-lymphadenectomy-for-endometrial-cancer-staging-fires-trial-a-multicentre-prospective-cohort-study
#10
Emma C Rossi, Lynn D Kowalski, Jennifer Scalici, Leigh Cantrell, Kevin Schuler, Rabbie K Hanna, Michael Method, Melissa Ade, Anastasia Ivanova, John F Boggess
BACKGROUND: Sentinel-lymph-node mapping has been advocated as an alternative staging technique for endometrial cancer. The aim of this study was to measure the sensitivity and negative predictive value of sentinel-lymph-node mapping compared with the gold standard of complete lymphadenectomy in detecting metastatic disease for endometrial cancer. METHODS: In the FIRES multicentre, prospective, cohort study patients with clinical stage 1 endometrial cancer of all histologies and grades undergoing robotic staging were eligible for study inclusion...
January 31, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28145916/hydronephrosis-presenting-6-months-after-sacral-colpopexy-case-report-and-literature-review
#11
Emily Weber LeBrun, Estefania Santamaria, Louis Moy
OBJECTIVES: The aim of this study was to describe a case of uterovaginal prolapse managed with robotic-assisted sacral colpopexy complicated by severe right-sided hydronephrosis despite normal intraoperative cystoscopy. METHODS: A 68-year-old woman presented with a worsening vaginal bulge over the past 2 years. Tricompartment stage 2 uterovaginal prolapse, with dominant cystocele and skin erosion at the posterior fourchette from prolapse friction, was identified on physical examination, and the patient underwent pelvic reconstructive surgery, including sacral colpopexy...
January 31, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28126218/imaging-genitourinary-trauma
#12
REVIEW
Bari Dane, Alexander B Baxter, Mark P Bernstein
Contrast-enhanced multidetector computed tomography (MDCT) has become a critical tool in the evaluation of the trauma patient. MDCT can quickly and accurately assess trauma patients for renal, ureteral, and bladder injuries. Moreover, CT guides clinical management triaging patients to those requiring discharge, observation, angioembolization, and surgery. Recognition of urinary tract trauma on initial scan acquisition should prompt delayed excretory phase imaging to identify urine leaks. Urethral and testicular trauma are imaged with retrograde urethrography and sonography, respectively...
March 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28119847/ureteral-rupture-caused-by-a-suprapubic-catheter-in-a-male-patient-with-spinal-cord-injury-a-case-report
#13
Hye Jung Choi, Chang Han Lee, Heesuk Shin
Spinal cord injury (SCI) may lead to urinary system disturbances. Patients with SCI usually have neurogenic bladder, and treatment optionss for this condition include clean intermittent catheterization and a permanent indwelling urethral or suprapubic catheter. Complications of catheterization include urinary tract infection, calculi, urinary tract injury, bladder contraction, bladder spasm, renal dysfunction, bladder cancer, and so forth. To the best of our knowledge, ureteral rupture is an unusual complication of catheterization, and ureteral rupture has been rarely reported in SCI patients...
December 2016: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28104123/diffusion-tensor-imaging-mri-with-spin-echo-sequence-and-long-duration-measurement-for-evaluation-of-renal-fibrosis-in-a-rat-fibrosis-model
#14
J-Y Kaimori, Y Isaka, M Hatanaka, S Yamamoto, N Ichimaru, A Fujikawa, H Shibata, A Fujimori, S Miyoshi, T Yokawa, K Kuroda, T Moriyama, H Rakugi, S Takahara
BACKGROUND: Renal fibrosis (RF) is a well-known marker for chronic kidney disease (CKD) progression, including chronic renal injury after renal transplantation. However, invasive biopsy is an available examination for evaluation of RF. Diffusion MRI was once recognized as a promising option for RF. However, it is now controversial for RF evaluation in a unilateral ureteral obstruction (UUO) model. METHODS: To seek an optimal imaging method applicable for RF in UUO model kidneys, we attempted a series of MRI methods, including proton density-weighted imaging, T1-weighted imaging, T2-weighted imaging, T2*-weighted imaging, diffusion-weighted imaging, and diffusion tensor imaging (DTI)...
January 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28075469/urinary-kidney-injury-molecule%C3%A2-1-as-an-early-diagnostic-biomarker-of-obstructive-acute-kidney-injury-and-development-of-a-rapid-detection-method
#15
Yingli Jin, Xiaona Shao, Bo Sun, Chunsheng Miao, Zhengqiang Li, Yan Shi
The aim of the present study was to investigate whether urinary kidney injury molecule‑1 (KIM‑1) presents a suitable early diagnostic biomarker of obstructive nephropathy‑induced acute kidney injury (AKI), and to develop a rapid detection method for urinary KIM‑1. Obstructive AKI was induced in an experimental rat model by a unilateral ureteral obstruction (UUO) operation. Macro‑ and micromorphological kidney alterations were determined by visual observation and hematoxylin and eosin (HE) staining, respectively...
January 5, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28075040/n-acetyl-seryl-aspartyl-lysyl-proline-mediates-the-anti-fibrotic-properties-of-captopril-in-unilateral-ureteric-obstructed-balb-c-mice
#16
Gary Cw Chan, Hao Jia Wu, Kam Wa Chan, Stella Yiu, Ailis Zou, Xiao Ru Huang, Hui Yao Lan, Kar Neng Lai, Sydney Cw Tang
BACKGROUND: Angiotensin-converting enzyme inhibitors (ACEi) are widely employed to deter the progression of chronic kidney disease (CKD). Besides controlling hypertension and reduction of intra-glomerular pressure, ACEi appear to have anti-fibrotic effects in the renal cortex. N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP), an endogenous tetrapeptide that is degraded by ACE, has also been shown to ameliorate the pro-fibrotic phenotype displayed in CKD in our recent study. Whether the anti-fibrotic properties of ACEi are mediated by Ac-SDKP has not been fully investigated...
January 11, 2017: Nephrology
https://www.readbyqxmd.com/read/28070723/anorectal-malformations-definitive-surgery-during-adulthood
#17
M P J Lopez, V I Encila, S G Alamo, H J Monroy Iii, M F T Roxas
BACKGROUND: Anorectal malformations (ARMs) are rarely seen in adults, since majority of cases are corrected in infancy or childhood. The aim of this study was to describe the profile of patients who underwent definitive surgery to correct their ARM in adulthood, and to discuss the outcomes of surgery (morbidity, mortality, and function). METHODS: This retrospective study included patients 18 years old and above, managed surgically by the Division of Colorectal Surgery at the Philippine General Hospital, University of the Philippines, Manila, from January 1, 2004, to December 31, 2012...
January 9, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28056942/the-guidewire-coil-technique-to-prevent-retrograde-stone-migration-of-ureteric-calculi-during-intracorporeal-lithothripsy
#18
Nici Markus Dreger, Friedrich Carl von Rundstedt, Stephan Roth, Alexander Sascha Brandt, Stephan Degener
BACKGROUND: Stone retropulsion represents a challenge for intracorporeal lithotripsy of ureteral calculi. The consequences are an increased duration and cost of surgery as well as decreased stone-free rates. The use of additional tools to prevent proximal stone migration entails further costs and risks for ureteral injuries. We present the simple technique of using a coil of the routinely used guidewire to prevent stone retropulsion. METHODS: We retrospectively evaluated all patients with mid-to-proximal ureteral stones in 2014, which were treated by ureteroscopic lithotripsy (Ho: YAG and/or pneumatic lithotripsy)...
January 5, 2017: BMC Urology
https://www.readbyqxmd.com/read/28043890/integrin-alpha6-maintains-the-structural-integrity-of-the-kidney-collecting-system
#19
Olga M Viquez, Eugenia M Yazlovitskaya, Tianxiang Tu, Glenda Mernaugh, Pablo Secades, Karen K McKee, Elizabeth Georges-Labouesse, Adele De Arcangelis, Vito Quaranta, Peter Yurchenco, Leslie C Gewin, Arnoud Sonnenberg, Ambra Pozzi, Roy Zent
Laminins are a major constituent of the basement membranes of the kidney collecting system. Integrins, transmembrane receptors formed by non-covalently bound α and β subunits, serve as laminin receptors, but their role in development and homeostasis of the kidney collecting system is poorly defined. Integrin α3β1, one of the major laminin receptors, plays a minor role in kidney collecting system development, while the role of α6 containing integrins (α6β1 and α6β4), the other major laminin receptors, is unknown...
December 30, 2016: Matrix Biology: Journal of the International Society for Matrix Biology
https://www.readbyqxmd.com/read/28024198/an-evaluation-of-laparoscopic-hysterectomy-alone-versus-in-combination-with-laparoscopic-myomectomy-for-patients-with-uterine-fibroids
#20
Fumiaki Taniguchi, Natsuki Koike, Tadayuki Kikukawa, Maki Yabuta, Masami Yamaguchi, Emi Adachi, Takeo Nakayama
OBJECTIVE: The purpose of this study was to compare surgical outcomes following conventional laparoscopic hysterectomy (LH) (C-LH) versus the combination method of LH plus laparoscopic myomectomy (LM) (LH+LM) for the treatment of large uterine fibroids. STUDY DESIGN: This study was performed in 56 patients (uterine weights ≥500g) who underwent either C-LH or LH+LM performed by the same surgeon between May 2010 and May 2016. LH+LM was performed when C-LH was problematic because of poor visibility and/or mobility due to uterine fibroids...
December 6, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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