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Ureteral injury

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https://www.readbyqxmd.com/read/29340810/ureteral-stents-increase-risk-of-postoperative-acute-kidney-injury-following-colorectal-surgery
#1
Taryn E Hassinger, J Hunter Mehaffey, Matthew G Mullen, Alex D Michaels, Nathan R Elwood, Shoshana T Levi, Traci L Hedrick, Charles M Friel
BACKGROUND: Ureteral stents are commonly placed before colorectal resection to assist in identification of ureters and prevent injury. Acute kidney injury (AKI) is a common cause of morbidity and increased cost following colorectal surgery. Although previously associated with reflex anuria, prophylactic stents have not been found to increase AKI. We sought to determine the impact of ureteral stents on the incidence of AKI following colorectal surgery. METHODS: All patients undergoing colon or rectal resection at a single institution between 2005 and 2015 were reviewed using American College of Surgeons National Surgical Quality Improvement Program dataset...
January 16, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29329595/human-umbilical-cord-mesenchymal-stem-cell-conditioned-medium-attenuates-renal-fibrosis-by-reducing-inflammation-and-epithelial-to-mesenchymal-transition-via-the-tlr4-nf-%C3%AE%C2%BAb-signaling-pathway-in-vivo-and-in-vitro
#2
Bo Liu, Fengxia Ding, Dong Hu, Yu Zhou, Chunlan Long, Lianju Shen, Yuanyuan Zhang, Deying Zhang, Guanghui Wei
BACKGROUND: Renal fibrosis is characterized by infiltration of interstitial inflammatory cells and release of inflammatory mediators, activation and proliferation of fibroblasts, and deposition of excessive extracellular matrix (ECM). The aim of this study was to evaluate the effect of human umbilical cord-derived mesenchymal stem cell (hucMSC) conditioned medium (CM) on renal tubulointerstitial inflammation and fibrosis. METHODS: Renal interstitial fibrosis was prepared in vivo using the unilateral ureteral obstruction (UUO)...
January 12, 2018: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29305252/the-anatomy-of-the-sacral-promontory-how-to-avoid-complications-of-the-sacrocolpopexy-procedure
#3
Géraldine Giraudet, Aurore Protat, Michel Cosson
Because of problems with vaginal meshes and high rate recurrences of native tissue repair, more and more surgeons treat pelvic organ prolapse performing laparoscopic sacrocolpopexy. This surgery requires skilled surgeons. The first step of sacrocolpopexy is the dissection of tissues in front of the sacral promontory to reach the anterior longitudinal ligament. Some complications can occur during this dissection and the attachment of the mesh. This place is dangerous for surgeons because of the proximity of vessels, nerves and ureters...
January 2, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29288787/robotic-appendiceal-interposition-with-right-lower-pole-calycostomy-downward-nephropexy-and-psoas-hitch-for-the-management-of-an-iatrogenic-near-complete-ureteral-avulsion
#4
Martus Gn, Ziho Lee, David Strauss, Daniel Eun
Although iatrogenic ureteral injuries are rare, they have potentially devastating consequences for both patients and physicians, and their management remains challenging. We report a case of a 51-year-old morbidly obese (BMI=63) female who suffered an iatrogenic 15 centimeter right ureteral avulsion during hysteroscopic biopsy. Preoperative antegrade and retrograde pyelograms demonstrated no true renal pelvis and a 3 centimeter blind-ending distal ureteral stump. The patient underwent a right robotic downward nephropexy, psoas hitch, lower pole calycostomy and 11 cm appendiceal interposition...
December 27, 2017: Urology
https://www.readbyqxmd.com/read/29278234/diagnostic-and-treatment-guidelines-for-gastrointestinal-and-genitourinary-endometriosis
#5
Stacy Young, Megan Kennedy Burns, Lucia DiFrancesco, Azadeh Nezhat, Camran Nezhat
Endometriosis is commonly misdiagnosed, even among many experienced gynecologists. Gastrointestinal and genitourinary endometriosis is particularly difficult to diagnose, and is commonly mistaken for other pathologies, such as irritable bowel syndrome, interstitial cystitis, and even psychological disturbances. This leads to delays in diagnosis, mismanagement, and unnecessary testing. In this review, we will discuss the diagnosis and management of genitourinary and gastrointestinal endometriosis. Medical management may be tried first, but often fails in cases of urinary tract endometriosis...
December 15, 2017: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/29276099/lethal-3-malignant-brain-tumor-like-2-l3mbtl2-protein-protects-against-kidney-injury-by-inhibiting-the-dna-damage-p53-apoptosis-pathway-in-renal-tubular-cells
#6
Huihui Huang, Chunhua Xu, Yang Wang, Chenling Meng, Wenjing Liu, Yueshui Zhao, Xiao-Ru Huang, Wenxing You, Bo Feng, Zhi-Hua Zheng, Yu Huang, Hui-Yao Lan, Jinzhong Qin, Yin Xia
DNA damage contributes to renal tubular cell death during kidney injury, but how DNA damage in tubular cells is regulated is not fully understood. Lethal (3) malignant brain tumor like 2 (L3MBTL2), a novel polycomb group protein, has been implicated in regulating chromatin architecture. However, the biological functions of L3MBTL2 are largely undefined. Here we found that L3MBTL2 was expressed in the nuclei of renal tubular epithelial cells in mice. Ablation of L3mbtl2 in renal tubular cells resulted in increases in nuclear DNA damage, p53 activation, apoptosis, tubular injury and kidney dysfunction after cisplatin treatment or unilateral ureteral obstruction...
December 21, 2017: Kidney International
https://www.readbyqxmd.com/read/29275598/-feasibility-of-susceptibility-weighted-imaging-in-the-evaluation-of-renal-fibrosis-induced-by-unilateral-ureteral-obstruction-in-white-rabbits
#7
J G Zhang, Z Y Xing, T T Zha, X J Tian, S J Xing, X Pan, L Xu, L Pan, W Xing, J Chen
Objective: To evaluate the feasibility of susceptibility weighted imaging (SWI) to reflect the progression of renal fibrosis (RF) induced by unilateral ureteral obstruction (UUO) in rabbits. Methods: Total of 32 New Zealand white rabbits (aged 4-5 months) were used to establish the UUO model (RF group) and were divided into 4 subgroups (including RF-2W group, RF-4W group , RF-6W group and RF-8W group) according to the duration of obstruction(2, 4, 6 and 8 weeks). Another 8 rabbits, underwent sham operation, were used as the control group (Sham group)...
December 5, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29273706/delayed-diagnosis-of-ureteral-injury-following-penetrating-abdominal-trauma-a-case-report-and-review-of-the-literature
#8
Kadhim M Taqi, Manar Mohammed Nassr, Jihad Salim Al Jufaili, Alla Ibrahim Abu-Qasida, Joseph Mathew, Hani Al-Qadhi
BACKGROUND Ureteral injuries are considered to be uncommon in cases of trauma. The possibility of damage to the ureters may not be considered in the setting of acute trauma when life-threatening injuries take clinical management priority. A case of acute ureteral injury is described in a patient with acute penetrating gunshot abdominal injury that had a delay in diagnosis, with a review of the literature. CASE REPORT A 29-year-old woman presented to our hospital with a missed ureteral injury following a self-inflicted gunshot injury to the abdomen...
December 23, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29243772/treating-ureteric-obstruction-secondary-to-gynecological-disease-assisted-with-retrograde-ureteroscopic-stenting
#9
J-C Chen, S-X Zhu, L-G Ren, J Chen, W Zhang
OBJECTIVE: To analyze the technical experience and clinical efficacy of ureteroscopic treatment of middle and lower ureteral obstruction due to gynecological disease. PATIENTS AND METHODS: From January 2007 to December 2015, 58 cases of ureteral obstruction were collected in 55 patients caused by gynecological factors. 19 cases had the history of gynecological iatrogenic injury and 39 cases were secondary to gynecological tumors. Different situations of luminal stenosis included obliteration, suture penetration, transection and unrecognized ureteral orifice...
December 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29237753/troy-tnfrsf19-marks-epithelial-progenitor-cells-during-mouse-kidney-development-that-continue-to-contribute-to-turnover-in-adult-kidney
#10
Frans Schutgens, Maarten B Rookmaaker, Francis Blokzijl, Ruben van Boxtel, Robert Vries, Edwin Cuppen, Marianne C Verhaar, Hans Clevers
During kidney development, progressively committed progenitor cells give rise to the distinct segments of the nephron, the functional unit of the kidney. Similar segment-committed progenitor cells are thought to be involved in the homeostasis of adult kidney. However, markers for most segment-committed progenitor cells remain to be identified. Here, we evaluate Troy/TNFRSF19 as a segment-committed nephron progenitor cell marker. Troy is expressed in the ureteric bud during embryonic development. During postnatal nephrogenesis, Troy+ cells are present in the cortex and papilla and display an immature tubular phenotype...
December 13, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29234532/bilateral-same-session-ureterorenoscopy-a-feasible-approach-to-treat-pan-urinary-stone-disease
#11
Bora Özveren, Murat Tugrul Eren, Hakan Özveri, Uğur Altuğ, Ahmet Şahin
Objectives: To assess treatment effectiveness and safety of bilateral same-session ureterorenoscopy (BSSU) for the management of stone disease involving the entire urinary system. Patients and methods: We reviewed the records of 64 patients who underwent BSSU for the treatment of bilateral ureteric and/or kidney stones. Size, number, location per side, and the total burden of stones were recorded. Data on stenting, lithotripsy, and stone retrieval, and details of hospital stay and operation times were investigated...
December 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29229740/bone-marrow-derived-cpla2%C3%AE-contributes-to-renal-fibrosis-progression
#12
John R Montford, Allison M B Lehman, Colin D Bauer, Jelena Klawitter, Jost Klawitter, Joanna M Poczobutt, Micah Scobey, Mary Weiser-Evans, Raphael A Nemenoff, Seth B Furgeson
The group IVA calcium dependent cytosolic phospholipase A2 enzyme (cPLA2α) directs a complex eicosanoid storm which accompanies the tissue response to injury. cPLA2α, and its downstream eicosanoid mediators, are also implicated in the pathogenesis of fibrosis in many organs including the kidney. We aimed to determine the role of cPLA2α in bone marrow-derived cells in a murine model of renal fibrosis, unilateral ureteral obstruction (UUO). Wild type (WT) C57BL/6J mice were irradiated and engrafted with donor bone marrow from either WT mice (WT-BMT) or mice deficient in cPLA2α (KO-BMT)...
December 11, 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/29229340/an-unusual-case-of-ureteral-perforation-in-minimally-invasive-pedicle-screw-instrumentation-and-review-of-the-literature
#13
Edward Fomekong, Julien Pierrard, Etienne Danse, Bertrand Tombal, Christian Raftopoulos
BACKGROUND: and Importance: Injury of the ureter is a potentially devastating complication most often reported in gynecologic, colorectal, vascular pelvic surgery or endoscopic procedures for ureteric pathologies. We report a rare case of ureteral rupture occurring as a complication of percutaneous pedicle screw placement. CLINICAL PRESENTATION: A 60-year old man complained of unbearable abdominal pain on the day after right L4-L5 transforaminal intervertebral fusion and percutaneous pedicle screw placement...
December 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29225120/retained-bullet-in-the-kidney-imaging-and-conservative-management
#14
Guglielmo Mantica, Stephan Kruger, Hilgard Ackermann, Pieter V Spies, Farzana Cassim, Zamira Keyser, Carlo Terrone, André van der Merwe
Renal gunshot wounds resulting in a grade IV injury (AAST) should be explored only if they involve the hilum or if there are signs of suspected renal pelvis or ureteral laceration, active haemorrhage, peritonitis or hemodynamically unstable patients.1 However, due to the paucity of cases reported in the literature, it is not clear what the best management of patients with a retained bullet is, which have been traditionally treated with surgical retrieval in other organs. We present the radiological findings and a clinical case summary of a patient with Grade IV kidney injury and retained bullet managed conservatively...
December 7, 2017: Urology
https://www.readbyqxmd.com/read/29215524/urinary-tract-injury-in-gynecologic-laparoscopy-for-benign-indication-a-systematic-review
#15
REVIEW
Jacqueline M K Wong, Pietro Bortoletto, Jocelyn Tolentino, Michael J Jung, Magdy P Milad
OBJECTIVE: To perform a comprehensive literature review of the incidence, location, etiology, timing, management, and long-term sequelae of urinary tract injury in gynecologic laparoscopy for benign indication. DATA SOURCES: A systematic review of PubMed, EMBASE, Cochrane Library, and ClinicalTrials.gov was conducted. METHODS OF STUDY SELECTION: Four hundred thirty-three studies were screened for inclusion with 136 full-text articles reviewed...
January 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29215477/prophylactic-ureteral-catheters-for-colectomy-a-national-surgical-quality-improvement-program-based-analysis
#16
Kathleen M Coakley, Kevin R Kasten, Stephanie M Sims, Tanushree Prasad, B Todd Heniford, Bradley R Davis
BACKGROUND: Despite improvement in technique and technology, using prophylactic ureteral catheters to avoid iatrogenic ureteral injury during colectomy remains controversial. OBJECTIVE: The aim of this study was to evaluate outcomes and costs attributable to prophylactic ureteral catheters with colectomy. DESIGN: This was a retrospective study. SETTINGS: The study was conducted at a single tertiary care center. PATIENTS: The colectomy-targeted American College of Surgeons National Surgical Quality Improvement Program database from 2012 to 2014 was queried...
January 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29212372/crowdsourcing-evaluation-of-ureteroscopic-videos-using-the-post-ureteroscopic-lesion-scale-puls-to-assess-ureteral-injury
#17
Kamaljot S Kaler, Zachary A Valley, Khiera C Bettir, Shoaib Safiullah, Daniel J Lama, Renai Yoon, Jaime Landman, Ralph Clayman
INTRODUCTION AND OBJECTIVES: We hypothesized that crowdsourcing assessments could be applied to the Post-Ureteroscopic Lesion Scale (PULS) for ureteral injury. METHODS: At a single institution, we prospectively digitally recorded 14 ureters at the terminal portion of standard ureteroscopic procedures. Each recording was reviewed by 10 global experts to determine a mean PULS score. Following training, the Crowd-Sourced Assessment of Technical Skills, C-SATS® (CSATS, Inc...
December 7, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29207359/telbivudine-attenuates-uuo-induced-renal-fibrosis-via-tgf-%C3%AE-smad-and-nf-%C3%AE%C2%BAb-signaling
#18
Jie Chen, Detian Li
Renal fibrosis yields decreased renal function and is a potent contributor to chronic kidney disease (CKD). Telbivudine (LdT) is an anti-hepatitis B virus (HBV) drug that has been found to steadily improve renal function, but the mechanism of drug action is unclear. One explanation is that LdT impacts inflammatory or fibrotic pathways. In this study, we investigated renal protection by LdT in a rat model of unilateral ureteral obstruction (UUO). UUO rats received oral gavage of LdT (1, 1.5, or 2g/kg/day) for 5weeks...
December 2, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/29207099/n-acetylcysteine-ameliorates-contrast%C3%A2-induced-kidney-injury-in-rats-with-unilateral-hydronephrosis
#19
Qiang Xia, Chunxiao Liu, Xia Zheng
The aim of the present study was to investigate the protective effects of N‑acetylcysteine (NAC) on contrast‑induced acute kidney injury in rats with unilateral hyronephrosis. Eighty‑two male Sprague Dawley rats were randomized to undergo sham operation (n=14) or unilateral ureteral obstruction (UUO) (n=68). After 3 weeks, the UUO animals were randomized to three groups: NAC gastric perfusion, UUO+iohexol+NAC (n=24); normal saline perfusion, UUO+iohexol (n=24); and controls, UUO (n=20). After 3 days, UUO+iohexol+NAC and UUO+iohexol rats were injected with iohexol...
November 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29202871/mesenchymal-stem-cell-derived-extracellular-vesicles-for-kidney-repair-current-status-and-looming-challenges
#20
REVIEW
Arash Aghajani Nargesi, Lilach O Lerman, Alfonso Eirin
Novel therapies are urgently needed to address the rising incidence and prevalence of acute kidney injury (AKI) and chronic kidney disease (CKD). Mesenchymal stem/stromal cells (MSCs) have shown promising results in experimental AKI and CKD, and have been used in the clinic for more than a decade with an excellent safety profile. The regenerative effects of MSCs do not rely on their differentiation and ability to replace damaged tissues, but are primarily mediated by the paracrine release of factors, including extracellular vesicles (EVs), composed of microvesicles and exosomes...
December 4, 2017: Stem Cell Research & Therapy
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