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Ureteral injury

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https://www.readbyqxmd.com/read/29162380/-results-of-conservative-surgical-management-of-ureteral-injuries
#1
J Soria, M Guandalino, N Vedrine, B Pereira, L Guy
INTRODUCTION: The ureter is a retroperitoneal organ. Ureteral injuries are rare, with a prevalence of 0.083% of surgical interventions over 10 years. The objective of this study was to evaluate the surgical management of ureteric injuries according to the time of discovery, their size and their location. We also evaluated the results of this management on the renal repercussion as well as the predictive factors of the severity of the ureteric injuries. MATERIAL AND METHODS: This was a monocentric retrospective study carried out on the basis of a systematic review of the CHU surgery files...
November 18, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/29157027/urinary-tract-injuries-during-cesarean-section-in-patients-with-morbid-placental-adherence-retrospective-cohort-study
#2
Ahmed Alanwar, Helmy M Al-Sayed, Ahmed M Ibrahim, Ahmed M Elkotb, Ahmed Abdelshafy, Rasha Abdelhadi, Ahmed M Abbas, Hend S Abdelmenam, Tamer Fares, Wael Nossair, Ameer A Abdallah, Haitham Sabaa, Maii Nawara
BACKGROUND/OBJECTIVE: The purpose of this study is to evaluate cases of lower urinary tract injuries during cesarean section with or without hysterectomy in cases with morbid placental adherence. METHODS: This record based retrospective study was conducted at Ain Shams University Maternity Hospital in Cairo, Egypt during the period between January 2014 and December 2016. It included all patients who had urinary tract injuries during cesarean section with or without hysterectomy in the cases with morbid placental adherence and they were collected from files of pregnant women who were admitted at hospital planned for termination of pregnancy...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29142908/a-rare-ureteral-injury-following-posterior-approach-lumbar-discectomy
#3
Mohammad Hajiha, Robert J Sowerby, Kenneth T Pace
Iatrogenic ureteral injuries account for ∼75% of all ureteral injuries and occur primarily during urologic, gynecologic, general, and vascular surgery procedures. Ureteral injury during spine surgery is a rare complication with only occasional reports in the literature. In this case report, we present a case of unrecognized left ureteral injury during an open right lumbar discectomy with a delayed presentation, and discuss the steps required for diagnosis and management. This report highlights a rare complication during laminectomy and serves to better inform patients and surgeons about this potential complication and the management options...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29135147/-biomarkers-of-renal-injury-in-contact-ureteral-lithotripsy
#4
A I Tarasenko, A M Pushkarev, I G Rakipov, A V Alekseev, Ya V Kondratenko, V N Pavlov
AIM: To optimize the transurethral endoscopic management of patients with ureterolithiasis by measuring biomarkers of renal parenchymal damage. MATERIALS AND METHODS: One hundred fifty-one patients with solitary ureteral stones were tested for levels of cystatin C, neutrophil gelatinase-associated lipocalin, 2-microglobulin and interleukin 18. RESULTS: An increase in the levels of markers of renal injury was observed both in the preoperative period and after CULT...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29130537/evaluation-of-renal-metabolic-response-to-partial-ureteral-obstruction-with-hyperpolarized-13-c-mri
#5
David J Niles, Jeremy W Gordon, Gengwen Huang, Shannon Reese, Erin B Adamson, Arjang Djamali, Sean B Fain
Hyperpolarized (13) C magnetic resonance imaging (MRI) may be used to non-invasively image the transport and chemical conversion of (13) C-labeled compounds in vivo. In this study, we utilize hyperpolarized (13) C MRI to evaluate metabolic markers in the kidneys longitudinally in a mouse model of partial unilateral ureteral obstruction (pUUO). Partial obstruction was surgically induced in the left ureter of nine adult mice, leaving the right ureter as a control. (1) H and hyperpolarized [1-(13) C]pyruvate MRI of the kidneys was performed 2 days prior to surgery (baseline) and at 3, 7 and 14 days post-surgery...
November 12, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/29126308/nrf2-deficiency-promotes-the-progression-from-acute-tubular-damage-to-chronic-renal-fibrosis-following-unilateral-ureteral-obstruction
#6
Weiwei Kong, Jingqi Fu, Nan Liu, Congcong Jiao, Guangying Guo, Junjun Luan, Huihui Wang, Li Yao, Lining Wang, Masayuki Yamamoto, Jingbo Pi, Hua Zhou
Background: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a central mediator of cellular responses to oxidative stress. We hypothesized that Nrf2 modulates progression from acute tubular damage to renal fibrosis. We asked whether Nrf2 deletion increases renal injury in mice following unilateral ureteral obstruction (UUO). Methods: We explored the time course of renal injury and Nrf2 expression in Nrf2+/+ mice following UUO. We compared Nrf2+/+ and Nrf2-/- mice following UUO in tubular damage, transdifferentiation [vimentin, proliferating cell nuclear antigen (PCNA)], fibrosis [fibronectin, α-smooth muscle actin (SMA)], antioxidative and inflammatory responses...
November 6, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29118551/importance-of-lower-pole-nephrectomy-during-ureterocalicostomy
#7
Anubhav Raj, Sharmad Kudchadker, Varun Mittal, Sandeep Nunia, Anil Mandhani
Ureterocalicostomy is usually a salvage procedure for recurrent pelvi-ureteric junction (PUJ) stricture or upper ureteric injury. It requires meticulous dissection of the upper ureter, and lower pole nephrectomy is considered an essential step to achieve a wide funneled and dependent ureterocaliceal anastomosis. We, hereby, highlight the importance of guillotine lower pole nephrectomy through a case report of recurrent PUJ stricture managed with ureterocalicostomy that failed due to the omission of lower pole nephrectomy...
October 2017: Urology Annals
https://www.readbyqxmd.com/read/29115561/inhibition-of-histone-deacetylase-1-ameliorates-renal-tubulointerstitial-fibrosis-via-modulation-of-inflammation-and-extracellular-matrix-gene-transcription-in-mice
#8
Tùng Nguyễn-Thanh, Dal Kim, Sik Lee, Won Kim, Sung Kwang Park, Kyung Pyo Kang
Renal tubulointerstitial fibrosis is characterized by sustained inflammation and excessive extracellular matrix (ECM) accumulation, leading to chronic kidney disease. Valproic acid (VPA) has anticancer activity through regulation of cell differentiation and apoptosis via inhibition of histone deacetylase (HDAC) activity and is considered a class I HDAC inhibitor. In this study, the effect of VPA on unilateral ureteral obstruction (UUO)‑induced renal fibrosis by modulation of renal inflammation and ECM gene transcription was investigated...
October 27, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29107072/ectopic-phosphorylated-creb-marks-dedifferentiated-proximal-tubules-in-cystic-kidney-disease
#9
Pawan Puri, Caitlin M Schaefer, Daniel Bushnell, Mary E Taglienti, Jordan A Kreidberg, Bradley K Yoder, Carlton M Bates
Ectopic cAMP signaling is pathological in polycystic kidney disease; however, its spatio-temporal actions are unclear. We characterized expression of phosphorylated Creb (p-Creb), a target and mediator of cAMP signaling, in developing and cystic kidney models. We also examined tubule-specific effects of cAMP analogs in cystogenesis in embryonic kidney explants. In wild-type mice, p-Creb marked nephron progenitors (NP), early epithelial NP derivatives, ureteric bud, and cortical stroma; p-Creb was present in differentiated thick ascending limb of Henle, collecting duct, and stroma; however, it disappeared in mature NP-derived proximal tubules...
October 26, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/29101337/trichostatin-a-ameliorates-renal-tubulointerstitial-fibrosis-through-modulation-of-the-jnk-dependent-notch-2-signaling-pathway
#10
Chun-Wu Tung, Yung-Chien Hsu, Chang-Jhih Cai, Ya-Hsueh Shih, Ching-Jen Wang, Pey-Jium Chang, Chun-Liang Lin
Renal fibrosis is the final common pathological feature in a variety of chronic kidney disease. Trichostatin A (TSA), a histone deacetylase inhibitor, reportedly attenuates renal fibrosis in various kidney disease models. However, the detailed molecular action of TSA in ameliorating renal fibrotic injury is not yet fully understood. In a cultured renal fibroblastic cell model, we showed that TGF-β1 triggers upregulation of α-SMA and fibronectin, two hallmarks of myofibroblastic activation. During the course of TGF-β1 treatment, activation of Smad2/3, p38, ERK, JNK and Notch-2 was also detected...
November 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29101170/the-prorenin-receptor-in-the-cardiovascular-system-and-beyond
#11
Matthew T Hennrikus, Alexis A Gonzalez, Minolfa C Prieto
Since the prorenin receptor (PRR) was first reported, investigations into its role in many cellular processes have been underway. Renin and prorenin binding to PRR and its soluble form (sPRR) increases angiotensin I formation and intracellular pathways resulting in induction of profibrotic factors. The PRR has supplementary roles as a vital accessory protein of the vacuolar-type H+-ATPase and also as an intermediate in Wnt signaling. As a component of the H-ATPase, the PRR has been found upregulated during cardiac stress...
November 3, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29100586/trends-of-ureteral-stent-usage-in-surgery-for-diverticulitis
#12
Alexander S Chiu, Raymond A Jean, Jolanta Gorecka, Kimberly A Davis, Kevin Y Pei
BACKGROUND: Many believe that the use of ureteral stents in colorectal surgery for diverticulitis aids prevention and easier identification of ureteral injuries; others argue that the added time, cost, and risks of stent placement negate potential benefits. Even among providers who use stents, selective use is common. Among unclear consensus, it remains unknown if the use of stents is growing. MATERIALS: Patients in the National Inpatient Sample who underwent a partial colectomy or anterior rectal excision for diverticulitis between 2000 and 2013 were included (n = 811,071)...
October 31, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/29098200/ureteral-obstruction-due-to-radiolucent-atazanavir-ureteral-stones
#13
Michael T Grant, Brian H Eisner, Seth K Bechis
Background: Protease inhibitors (PIs) are a well-documented cause of nephrolithiasis. Although medications such as indinavir are known to increase risk of stone formation, the association of newer HIV medications is not as well studied. In this study, we report a case of a patient who developed atazanavir stones. Case Presentation: A 74-year-old man with HIV on antiretroviral therapy-including atazanavir, a PI-presented with right flank pain. He previously had passed two ureteral stones that were not analyzed...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29095073/surgical-management-of-haemophilic-pseudotumors-experience-in-a-developing-country
#14
Yu He, Xi Zhou, Haomin Cui, Guixing Qiu, Xisheng Weng, Baozhong Zhang, Yong Liu
AIM: Hemophilic pseudotumors result from repeated episodes of bleeding into bone, subperiosteum, and soft tissue. Since clotting factors became available, uncontrolled perioperative bleeding is a less significant problem for surgeons in developed countries. However, they are more difficult to come by in China. Additionally, patients often have to undergo surgery for giant masses and suffer complications. We wanted to present our experience in the surgical management of hemophilic pseudotumors over a 40-year period...
November 2, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29082329/a-rare-case-report-of-hydronephrosis-and-acute-kidney-injury-secondary-to-gonadal-vein-thrombosis-in-a-young-male
#15
Jason M Sandberg, Raymond B Dyer, Majid Mirzazadeh
Background: Gonadal vein thrombosis (GVT) has been reported in association with malignancy and pelvic inflammatory conditions. Patients who develop GVT often require systemic anticoagulation to reduce the risk of pulmonary embolism and other local and distant thromboembolic effects. As the gonadal vein courses from the pelvis toward its outlet in the upper abdomen, its intimate relationship to the ureter in the setting of vascular pathology may pose a risk for urinary obstruction in the adult. We are reporting a rare case of GVT leading to ureteral obstruction and acute kidney injury (AKI) in a young otherwise healthy male and provide a review of similar literature...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29082326/-valve-type-retainment-of-flexible-ureteroscope-in-the-distal-ureter
#16
Nariman Gadzhiev, Vladislav Grigoryev, Zhamshid Okhunov, Nobel Nguyen, Aleksei Pisarev, Bairamov Hikmet, Sergei Petrov
Introduction: Flexible ureteroscopy (fURS) is an endoscopic procedure for the minimally invasive treatment of ureteral and renal calculi. Due to improvements in technique and ureteroscopic instrumentation over the past two decades, complications associated with URS are infrequent. However, in the event of an unexpected device malfunction or failure, the operating surgeon must employ prompt, resolute decision-making to resolve any intraoperative complications and avoid significant injury to the kidney or ureter...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29069033/postrenal-acute-kidney-injury-in-a-patient-with-unilateral-ureteral-obstruction-caused-by-urolithiasis-a-case-report
#17
Itsuro Kazama, Toshiyuki Nakajima
RATIONALE: In patients with bilateral ureteral obstruction, the serum creatinine levels are often elevated, sometimes causing postrenal acute kidney injury (AKI). In contrast, those with unilateral ureteral obstruction present normal serum creatinine levels, as long as their contralateral kidneys are preserved intact. However, the unilateral obstruction of the ureter could affect the renal function, as it humorally influences the renal hemodynamics. PATIENT CONCERNS: A 66-year-old man with a past medical history of hypertension and diabetes mellitus came to our outpatient clinic because of right abdominal dullness...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29067044/acute-kidney-injury-in-ureteric-stones-single-centre-short-term-analysis
#18
Huma Mamun Mahmud, Syed Mamun Mahmud
OBJECTIVE: To analyze acute kidney injury (AKI) frequency, risk factors and outcome in ureteric stone patients. METHODS: This is an observational retrospective study performed in a single tertiary care centre in Abu Dhabi from October 2014 till August 2015. Convenient sampling was done on 152 consecutive patients who underwent decompression surgery (Ureterorenoscopy LASER Lithotripsy and DJ Stenting) for ureteric stones. Serum Creatinine was used to calculate creatinine clearance by cock croft Gault formula in all patients before and after procedure...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29048226/effect-of-laser-settings-and-irrigation-rates-on-ureteral-temperature-during-holmium-laser-lithotripsy-an-in-vitro-model
#19
Daniel A Wollin, Evan C Carlos, Westin R Tom, W Neal Simmons, Glenn M Preminger, Michael E Lipkin
PURPOSE: Ureteroscopic laser lithotripsy requires irrigation for adequate visualization and temperature control during treatment of ureteral stones. However, there are little data on how different irrigation and laser settings affect the ureteral wall and surrounding tissues. This effect has become an important consideration with the advent of high-powered lasers. We therefore evaluated the effect of laser settings and irrigation flow on ureteral temperature in an in vitro setting. MATERIALS AND METHODS: To mimic ureteroscopic laser lithotripsy, we simulated clinically relevant irrigation flow rates and fired a Holmium:Yttrium-aluminum-garnet (Ho:YAG) laser while monitoring "intraureteral" temperature...
November 15, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29047410/association-between-kidney-intracapsular-pressure-and-ultrasound-elastography
#20
Kianoush B Kashani, Shennen A Mao, Sami Safadi, Bruce P Amiot, Jaime M Glorioso, John C Lieske, Scott L Nyberg, Xiaoming Zhang
BACKGROUND: Kidney congestion is a common pathophysiologic pathway of acute kidney injury (AKI) in sepsis and heart failure. There is no noninvasive tool to measure kidney intracapsular pressure (KIP) directly. METHODS: We evaluated the correlation of KIP with kidney elasticity measured by ultrasound surface wave elastography (USWE). We directly measured transcatheter KIP in three pigs at baseline and after bolus infusion of normal saline, norepinephrine, vasopressin, dopamine, and fenoldopam; infiltration of 2-L peritoneal dialysis solution in the intra-abdominal space; and venous, arterial, and ureteral clamping...
October 19, 2017: Critical Care: the Official Journal of the Critical Care Forum
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