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https://www.readbyqxmd.com/read/28821193/therapeutic-plasma-exchange-and-its-impact-on-drug-levels-an-aclps-critical-review
#1
Caleb W Cheng, Jeanne E Hendrickson, Christopher A Tormey, Davinder Sidhu
Objectives: To examine and summarize the current literature on the effects of therapeutic plasma exchange on medication levels. Methods: Literature review was performed via searches of the Cochrane Database and PubMed-MEDLINE (1996 to August 2016) looking for all case reports, case series, and human randomized controlled trials involving therapeutic plasma exchange (TPE)-associated drug removal. Results: Approximately 60 peer-reviewed articles were identified with the majority being case reports; no randomized controlled trials were identified...
September 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28820144/chinese-expert-consensus-statement-on-issues-related-to-small-specimen-sampling-of-lung-cancer
#2
(no author information available yet)
No abstract text is available yet for this article.
July 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28819961/-bioresorbable-scaffolds-in-the-treatment-of-coronary-artery-disease-expert-consensus-statement-of-the-association-of-cardiovascular-interventions-of-the-polish-cardiac-society-acvi-pcs
#3
Krzysztof Reczuch, Krzysztof Milewski, Wojciech Wąsek, Łukasz Rzeszutko, Wojciech Wojakowski, Michał Hawranek, Adrian Włodarczak, Tomasz Pawłowski, Janusz Kochman, Sławomir Dobrzycki, Marek Grygier, Andrzej Ochała, Jarosław Wójcik, Maciej Lesiak, Dariusz Dudek, Jacek Legutko
Bioresorbable scaffold coated with antimitotic drug is the latest development in the coronary stents technology. The concept of temporary scaffolding and natural vessel healing after angioplasty is a very attractive alternative to conventional metal stents. The results of the first observational studies have confirmed their ultimate biodegradation. Newest results of randomised trials and registries in broader clinical and anatomical indications also revealed the limitations of the first generation of scaffolds...
2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28819916/early-surgical-intervention-for-acute-ulcerative-colitis-is-associated-with-improved-postoperative-outcomes
#4
Ira L Leeds, Brindusa Truta, Alyssa M Parian, Sophia Y Chen, Jonathan E Efron, Susan L Gearhart, Bashar Safar, Sandy H Fang
BACKGROUND: Timing of surgical intervention for acute ulcerative colitis has not been fully examined during the modern immunotherapy era. Although early surgical intervention is recommended, historical consensus for "early" ranges widely. The purpose of this study was to evaluate outcomes according to timing of urgent surgery for acute ulcerative colitis. METHODS: All non-elective total colectomies in ulcerative colitis patients were identified in the National Inpatient Sample from 2002 to 2014...
August 17, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28819911/neighborhood-family-and-peer-factors-associated-with-early-adolescent-smoking-and-alcohol-use
#5
Christopher Cambron, Rick Kosterman, Richard F Catalano, Katarina Guttmannova, J David Hawkins
There is broad agreement that neighborhood contexts are important for adolescent development, but there is less consensus about their association with adolescent smoking and alcohol use. Few studies have examined associations between neighborhood socioeconomic contexts and smoking and alcohol use while also accounting for differences in family and peer risk factors for substance use. Data drawn from the Seattle Social Development Project (N = 808), a gender-balanced (female = 49%), multiethnic, theory-driven longitudinal study originating in Seattle, WA, were used to estimate trajectories of smoking and alcohol use from 5th to 9th grade...
August 18, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28819895/optimal-lymphadenectomy-in-small-bowel-neuroendocrine-tumors-analysis-of-the-ncdb
#6
Benjamin M Motz, Patrick D Lorimer, Danielle Boselli, Joshua S Hill, Jonathan C Salo
BACKGROUND: Current National Comprehensive Cancer Network guidelines for resectable small bowel neuroendocrine tumors (NETs) recommend regional lymphadenectomy. However, no consensus exists on the optimal nodal harvest. METHODS: The National Cancer Database was queried for patients with resectable small bowel NETs (1998-2013). Patients with metastatic disease and missing lymph node harvest data were excluded. We performed logistic regression of factors determining nodal positivity and multivariable survival analyses...
August 17, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28819824/-update-pulmonary-arterial-hypertension-definitions-diagnosis-therapy
#7
N Sommer, M J Richter, K Tello, F Grimminger, W Seeger, H A Ghofrani, H Gall
The term pulmonary arterial hypertension comprises a group of pulmonary vascular diseases of different etiologies that are characterized by similar precapillary vascular remodeling processes and result in exertional dyspnea and right heart insufficiency. The specific pharmacological treatment approach considers the risk of mortality and phenotypical properties and includes treatment with phosphodiesterase type 5 inhibitors, endothelin receptor antagonists and prostanoids, as well as with more novel substances, such as a soluble guanylyl cyclase stimulator and an oral prostacyclin receptor agonist...
August 17, 2017: Der Internist
https://www.readbyqxmd.com/read/28819813/-teriparatide-as-a%C3%A2-therapy-approach-in-sacral-insufficiency-fractures
#8
Gloria Hohenberger
As a result of immense heterogeneity with regard to morphology and stability, the recent literature lacks consensus concerning the treatment of sacral insufficiency fractures. We report the case of a 79-year-old woman with bilateral sacral insufficiency fractures following anterior pelvic ring fractures who was treated with teriparatide. During a two-week hospital stay, the patient was successfully mobilised and the regularly conducted pelvic X‑ray controls showed full consolidation of the fractures.
August 17, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28819810/laser-assisted-surgery-of-the-upper-aero-digestive-tract-a-clarification-of-nomenclature-a-consensus-statement-of-the-european-laryngological-society
#9
Marc Remacle, Christoph Arens, Mostafa Badr Eldin, Guillermo Campos, Carlos Chiesa Estomba, Pavel Dulguerov, Ivana Fiz, Anastasios Hantzakos, Jerôme Keghian, Francesco Mora, Nayla Matar, Giorgio Peretti, Cesare Piazza, Gregory N Postma, Vyas Prasad, Elisabeth Sjogren, Frederik G Dikkers
Acronyms and abbreviations are frequently used in otorhinolaryngology and other medical specialties. CO2 laser-assisted transoral surgery of the pharynx, the larynx and the upper airway is a family of commonly performed surgical procedures termed transoral laser microsurgery (TLM). The abbreviation TLM can be confusing because of alternative modes of delivery. Classification and definition of the different types of procedures, performed transorally or transnasally, are proposed by the Working Committee for Nomenclature of the European Laryngological Society, emphasizing the type of laser used and the way this laser is transmitted...
August 17, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28819491/-psychiatric-and-psychological-evaluation-of-tako-tsubo-syndrome-about-a-case
#10
Ghizlane Slimani, Hicham Lakbiri, Fatima Zahra Sekkat
Stress cardiomyopathy or Tako Tsubo cardiomyopathy is a cardiac pathology evoking acute coronary syndrome characterized by electrocardiographic signs, cardiac enzyme elevation and no obstructive coronary lesions. It generally affects postmenopausal women and it usually occurs after periods of intense stress. Disease onset is widely variable, ranging from anginal pain (most common) to cardiogenic shock. Exact pathophysiological mechanism continues to be debated. Various hypotheses have been posited. Abrupt elevation of adrenaline levels appears to be the most credible...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28819414/depletion-of-ctcf-in-breast-cancer-cells-selectively-induces-cancer-cell-death-via-p53
#11
Ji-Yeon Lee, Muhammad Mustafa, Clara Yuri Kim, Myoung Hee Kim
CCCTC-binding factor (CTCF), a ubiquitous 11-zinc finger multifunctional protein, has distinct molecular functions, such as transcriptional activation, repression, and chromatin barrier activity, in a locus-specific manner. Elevated CTCF levels in breast cancer cells are known to contribute to tumorigenesis; however, the underlying mechanism remains elusive. We investigated the effect of CTCF expression on breast cancer cell survival and elucidated its mechanism. CTCF depletion in MCF-7 cells led to a decreased cell growth and proliferation, surpassing the growth of normal cells under co-culture system of MCF-7-GFP and MCF10A...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28819341/reliability-of-the-acetabular-reconstruction-technique-using-autogenous-bone-graft-from-resected-femoral-head-in-hip-dysplasia-influence-of-the-change-of-hip-joint-center-on-clinical-outcome
#12
Joo Ho Song, Tae Soo Ahn, Pil Whan Yoon, Jae Suk Chang
INTRODUCTION: The previous studies have not reached on consensus as to the outcome of acetabular reconstruction with autogenous bone graft for dysplastic hips, especially in severe cases such as Crowe type IV. The current study aimed to determine the survivorship of the arthroplasty and the grafts as well as the change of hip joint center averagely 9.8 years (range, 5-19) after cementless total hip arthroplasty. MATERIALS AND METHODS: We reviewed 52 cases including 19 cases of complete hip dislocation of which acetabular defects were augmented with autogenous bone grafts taken from the resected femoral heads...
December 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28819091/review-of-current-evidence-regarding-surgery-in-elderly-patients-with-meningioma
#13
Fusao Ikawa, Yasuyuki Kinoshita, Masaaki Takeda, Taiichi Saito, Satoshi Yamaguchi, Fumiyuki Yamasaki, Koji Iida, Kazuhiko Sugiyama, Kazunori Arita, Kaoru Kurisu
The Japanese population features the highest rate of elderly individuals worldwide. Moreover, Japan has the highest number of computed tomography/magnetic resonance imaging devices in the world, which has led to an increase in the incidental detection of meningioma in healthy elderly patients. Many previous papers have discussed the risks and indications for surgery in this patient population, but available information remains insufficient, and the definition of "elderly" has not been standardized. This review tried to clarify the published evidence and challenges associated with elderly meningioma based on a search of the PubMed database using the terms "meningioma," "elderly," and "surgery" for English-language clinical studies and collected related papers published from 2000 to 2016...
August 15, 2017: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/28819089/follow-up-practices-of-surgeons-and-medical-oncologists-in-australia-and-new-zealand-following-resection-of-esophagogastric-cancers
#14
Tim Chew, Tim Bright, Timothy J Price, David I Watson, Peter G Devitt
PURPOSE: Follow-up practices for patients who have undergone surgical resection of esophagogastric malignancies are variable and poorly documented. To better understand practice, a questionnaire was used to survey surgeons and medical oncologists to determine whether any consensus exists. METHODS: An opt-in online questionnaire was sent to esophagogastric surgeons and medical oncologists via the membership lists for the Australian and New Zealand Gastric and Oesophageal Surgery Association (ANZGOSA), the Australian Gastro-Intestinal Trials Groups (AGITG), and the Medical Oncology Group of Australia (MOGA)...
August 15, 2017: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28819068/rural-emergency-care-360%C3%A2-mobilising-healthcare-professionals-decision-makers-patients-and-citizens-to-improve-rural-emergency-care-in-the-province-of-quebec-canada-a-qualitative-study-protocol
#15
Richard Fleet, Gilles Dupuis, Jean-Paul Fortin, Jocelyn Gravel, Mathieu Ouimet, Julien Poitras, France Légaré
INTRODUCTION: Emergency departments (EDs) are an important safety net for rural populations. Results of our earlier studies suggest that rural Canadian hospitals have limited access to advanced imaging services and intensive care units and that patients are transferred over large distances. They also revealed significant geographical variations in rural services. In the absence of national standards, our studies raise questions about inequities in rural access to emergency services and the risks for citizens...
August 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28818938/comprehensive-single-cell-transcriptional-profiling-of-a-multicellular-organism
#16
Junyue Cao, Jonathan S Packer, Vijay Ramani, Darren A Cusanovich, Chau Huynh, Riza Daza, Xiaojie Qiu, Choli Lee, Scott N Furlan, Frank J Steemers, Andrew Adey, Robert H Waterston, Cole Trapnell, Jay Shendure
To resolve cellular heterogeneity, we developed a combinatorial indexing strategy to profile the transcriptomes of single cells or nuclei, termed sci-RNA-seq (single-cell combinatorial indexing RNA sequencing). We applied sci-RNA-seq to profile nearly 50,000 cells from the nematode Caenorhabditis elegans at the L2 larval stage, which provided >50-fold "shotgun" cellular coverage of its somatic cell composition. From these data, we defined consensus expression profiles for 27 cell types and recovered rare neuronal cell types corresponding to as few as one or two cells in the L2 worm...
August 18, 2017: Science
https://www.readbyqxmd.com/read/28818646/best-practice-in-research-consensus-statement-on-ethnopharmacological-field-studies-consefs
#17
REVIEW
Michael Heinrich, Andreas Lardos, Marco Leonti, Caroline Weckerle, Merlin Willcox
BACKGROUND: Ethnopharmacological research aims at gathering information on local and traditional uses of plants and other natural substances. However, the approaches used and the methods employed vary, and while such a variability is desirable in terms of scientific diversity, research must adhere to well defined quality standards and reproducible methods OBJECTIVES: With ConSEFS (the Consensus Statement on Ethnopharmacological Field Studies) we want to define best-practice in developing, conducting and reporting field studies focusing on local and traditional uses of medicinal and food plants, including studies using a historical approach...
August 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28818633/patient-and-caregiver-reported-assessment-tools-for-palliative-care-summary-of-the-2017-ahrq-technical-brief
#18
Rebecca Aslakson, Sydney M Dy, Renee F Wilson, Julie Waldfogel, Allen Zhang, Sarina R Isenberg, Alex Blair, Joshua Sixon, Karen A Robinson
CONTEXT: Assessment tools are data collection instruments that are completed by or with patients or caregivers and which collect data at the individual patient or caregiver level. OBJECTIVES: To (1) summarize palliative care assessment tools completed by or with patients or caregivers, and (2) identify needs for future tool development and evaluation. METHODS: We completed: (1) a systematic review of systematic reviews; (2) a supplemental search of previous reviews and websites, and/or (3) a targeted search for primary articles when no tools existed in a domain...
August 14, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28818507/optimizing-quality-of-endoscopy-in-inflammatory-bowel-disease-focus-on-surveillance-and-management-of-colorectal-dysplasia-using-interactive-image-and-video-based-teaching
#19
Tonya R Kaltenbach, Roy M Soetikno, Rebecca DeVivo, Loren A Laine, Alan Barkun, Kenneth R McQuaid
BACKGROUND & AIMS: Varying recommendations regarding the detection and management of dysplasia can lead to uncertainty and may have impeded the uptake of strategies that could improve surveillance in patients with inflammatory bowel disease (IBD). As such, an educational event was held to assist in disseminating the recently published Surveillance for Colorectal Endoscopic Neoplasia Detection and Management in Inflammatory Bowel Disease Patients: International Consensus Recommendations (SCENIC)...
August 14, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28818505/schizophrenia-with-prominent-catatonic-features-a-selective-review
#20
Gabor S Ungvari, Jozsef Gerevich, Rozália Takács, Gábor Gazdag
A widely accepted consensus holds that a variety of motor symptoms subsumed under the term 'catatonia' have been an integral part of the symptomatology of schizophrenia since 1896, when Kraepelin proposed the concept of dementia praecox (schizophrenia). Until recently, psychiatric classifications included catatonic schizophrenia mainly through tradition, without compelling evidence of its validity as a schizophrenia subtype. This selective review briefly summarizes the history, psychopathology, demographic and epidemiological data, and treatment options for schizophrenia with prominent catatonic features...
August 14, 2017: Schizophrenia Research
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