Freya Lyssy, Désirée Forstner, Beatrice A Brugger, Kaja Ujčič, Jacqueline Guettler, Nadja Kupper, Stefan Wernitznig, Christine Daxboeck, Lena Neuper, Amin El-Heliebi, Teresa Kloimboeck, Julia Kargl, Berthold Huppertz, Nassim Ghaffari-Tabrizi-Wizsy, Martin Gauster
The study of very early human placentation is largely limited due to ethical restrictions on the use of embryonic tissue and the fact that the placental anatomy of common laboratory animal models varies considerably from that of humans. In recent years several promising models, including trophoblast stem cell-derived organoids, have been developed that have also proven useful for the study of important trophoblast differentiation processes. However, the consideration of maternal blood flow in trophoblast invasion models currently appears to be limited to animal models...
April 30, 2024: Placenta