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https://www.readbyqxmd.com/read/28211282/signet-ring-cell-carcinoma-of-the-jejunum-an-uncommon-finding-within-the-reach-of-capsule-endoscopy
#1
José Francisco Juanmartiñena, Marta Montes, Ignacio Fernández-Urién
An 80 year-old female presented with ductal breast carcinoma (stage II) three years ago, complained of asthenia and iron-deficiency anemia. No diagnosis was obtained after conventional endoscopy and iron supplements were indicated. Ten months later visible digestive hemorrhage was presented. Upper and lower endoscopy was repeated but non-diagnosis was obtained. Thus, video capsule endoscopy was indicated identifying a stenotic lesion arising in the mucosa of distal jejunum. Histopathological examination revealed a poorly mucinous differentiated signet-ring cell adenocarcinoma with an intense peri-tumoral lymphoid (Crohn´s-like lymphoid reaction) and lympho-vascular infiltration with no nodal metastases (pT3N0;7ª edition TNM classification)...
February 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28211279/diverticulitis-of-the-appendix-as-debut-of-appendicular-cystadenoma-and-carcinoid-tumor
#2
Laura Fernández Gómez-Cruzado, Mikel Prieto Calvo, Christian Pérez González, Jasone Larrea Oleaga
Appendiceal diverticulosis is a rare condition with a frequency of 0.004% to 2.1%, and is sometimes an occasional finding during anatomopathologic study of the surgical specimen. It may be presented acutely as a right lower quadrant pain, similar to acute appendicitis for which differential diagnosis must be carried out, and it is associated with appendicular tumors. We report a case of diverticulitis of the appendix as debut of appendicular cystadenoma and carcinoid tumor with representative iconography, being unusual the association of both diseases and even more its preoperative diagnosis...
February 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28211016/adenocarcinoma-ex-goblet-cell-carcinoid-of-the-appendix-a-case-report-and-overview-of-the-disease
#3
Uroosa Ibrahim, Gautam Valecha, Gwenalyn Garcia, Amina Saqib, Monika Wrzolek, Meekoo Dhar
No abstract text is available yet for this article.
February 17, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28208131/pulmonary-carcinoids-and-low-grade-gastrointestinal-neuroendocrine-tumors-show-common-microrna-expression-profiles-different-from-adenocarcinomas-and-small-cell-carcinomas
#4
Toyoki Yoshimoto, Noriko Motoi, Noriko Yamamoto, Hiroko Nagano, Masaru Ushijima, Masaaki Matsuura, Sakae Okumura, Toshiharu Yamaguchi, Masashi Fukayama, Yuichi Ishikawa
No abstract text is available yet for this article.
February 17, 2017: Neuroendocrinology
https://www.readbyqxmd.com/read/28205418/pediatric-neuroendocrine-carcinoid-tumors-management-pathology-and-imaging-findings-in-a-pediatric-referral-center
#5
Andrew J Degnan, Shannon Tocchio, Waleed Kurtom, Sameh S Tadros
BACKGROUND: While neuroendocrine (carcinoid) tumors are increasingly recognized in the adult population, they are often not suspected in children. PROCEDURE: Retrospective review of all well-differentiated neuroendocrine (carcinoid) tumors was performed based on pathology reports from a quaternary pediatric medical center between January 2003 and June 2016. Clinical presentations, treatment approaches, imaging findings, and outcomes were reviewed and analyzed. RESULTS: A total of 45 cases of pathology-proven carcinoid tumor were reported with an average age of 14...
February 16, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28205198/a-51-year-old-patient-with-carcinoid-heart-disease-and-severe-tricuspid-regurgitation
#6
Elżbieta Florczak, Mariola Pęczkowska, Marek Konka, Jacek Różański, Agnieszka Kolasińska-Ćwikła
No abstract text is available yet for this article.
2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28204100/is-there-a-role-for-traditional-nuclear-medicine-imaging-in-the-management-of-pulmonary-carcinoid-tumours-%C3%A2
#7
Maria Cattoni, Eric Vallières, Lisa M Brown, Amir A Sarkeshik, Stefano Margaritora, Alessandra Siciliani, Andrea Imperatori, Nicola Rotolo, Farhood Farjah, Grace Wandell, Kimberly Costas, Catherine Mann, Michal Hubka, Stephen Kaplan, Alexander S Farivar, Ralph W Aye, Brian E Louie
No abstract text is available yet for this article.
February 14, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28203372/diagnostic-challenges-and-management-of-a-patient-with-acromegaly-due-to-ectopic-growth-hormone-releasing-hormone-secretion-from-a-bronchial-carcinoid-tumour
#8
Nikolaos Kyriakakis, Jacqueline Trouillas, Mary N Dang, Julie Lynch, Paul Belchetz, Márta Korbonits, Robert D Murray
: A male patient presented at the age of 30 with classic clinical features of acromegaly and was found to have elevated growth hormone levels, not suppressing during an oral glucose tolerance test. His acromegaly was originally considered to be of pituitary origin, based on a CT scan, which was interpreted as showing a pituitary macroadenoma. Despite two trans-sphenoidal surgeries, cranial radiotherapy and periods of treatment with bromocriptine and octreotide, his acromegaly remained active clinically and biochemically...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28203303/refractory-carcinoid-syndrome-a-review-of-treatment-options
#9
REVIEW
Rachel P Riechelmann, Allan A Pereira, Juliana F M Rego, Frederico P Costa
Carcinoid syndrome (CSy) is a constellation of symptoms that may commonly present in patients with well differentiated neuroendocrine tumors (NETs), with somatostatin analogs (SSAs) being the first-line option for symptom management. However, symptomatic progression eventually occurs and in this scenario of a refractory CSy; several treatment options have been studied such as dose escalation of SSA, interferon and liver-directed therapies. Nevertheless, recent phase III trials have contributed to the understanding and management of this condition...
February 2017: Therapeutic Advances in Medical Oncology
https://www.readbyqxmd.com/read/28203126/an-unusual-case-of-rectal-and-ileal-carcinoid-tumors
#10
Molham Abdulsamad, Naeem Abbas, Bhavna Balar
Carcinoid tumor is the most common neuroendocrine tumor affecting the gastrointestinal tract. The coexistence of multifocal carcinoid lesions is a well-established phenomenon. Although intubation of the terminal ileum is not routinely attempted during colonoscopy, it can occasionally reveal the presence of some incidental findings. We present a patient with known rectal carcinoid, who was found to have another carcinoid lesion in the terminal ileum during surveillance colonoscopy. The patient underwent right hemicolectomy, and no chemotherapy was required as the patient was found to have stage 1 carcinoid tumor...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28202381/sphenoid-sinus-carcinoid-tumour-causing-ectopic-acth-syndrome
#11
Sanjaya Perera, Ahmad Taha
A thirty-eight year old patient presented with a gradual increase in weight and Cushingoid facies of two years duration. He also had orbital congestion, with puffy eyelids and corkscrew conjunctival vessels, associated with painful eye movements. An endocrine evaluation revealed raised cortisol and ACTH. Head imaging was performed which showed an enhancing tumour arising from the sphenoid sinus, with osseous erosion of the sphenoid sinus, extending to the nasopharynx, sellar and a small amount extending intracranially...
February 12, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28199138/pediatric-neuroendocrine-carcinoid-tumors-review-of-diagnostic-imaging-findings-and-recent-advances
#12
Andrew J Degnan, Sameh S Tadros, Shannon Tocchio
OBJECTIVE: Although rare, pediatric neuroendocrine tumors including carcinoid tumor have increased in incidence over the past few decades. Despite increased recognition, survival rates have not significantly improved. Earlier detection of these tumors is necessary to improve clinical outcomes. This article discusses imaging approaches for detecting pediatric carcinoid tumors including anatomic imaging methods such as CT and MRI as well as functional imaging methods targeting the somatostatin receptor including (111)In-labeled octreotide and newer (68)Ga-based radiotracers that may hold promise in hybrid PET/CT or PET/MRI...
February 15, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28195104/well-differentiated-neuroendocrine-tumor-of-the-kidney-report-of-a-rare-case-with-review-of-literature
#13
Kavita Mardi, Lalita Negi, Srijan Srivastava
Neuroendocrine tumors (NETs) are uncommon tumors that exhibit a wide range of neuroendocrine differentiation and biological behavior. Primary NETs of the kidney, including carcinoid tumor, small cell carcinoma (SCC), and large cell neuroendocrine carcinoma (LCNEC) are exceedingly rare. Renal carcinoids are typically slow-growing tumors and pursue a variable clinical course. In contrast, SCC and LCNEC often present with locally advanced or metastatic disease and carry a poor prognosis. We herein report a rare cases of well-differentiated NET (carcinoid) in a 39-year-old male along with the immunohistochemical features...
January 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28193185/intestinal-goblet-cell-carcinoid-presenting-with-recurrent-sterile-peritonitis-in-a-patient-on-peritoneal-dialysis-a-case-report
#14
Chih-Wei Chen, Jan-Show Chu, Li-Chun Hsieh, Chih-Chin Kao, Yen-Chung Lin, Hsi-Hsien Chen
BACKGROUND: Goblet cell carcinoid is a rare variant of appendiceal carcinoid with mixed endocrine and exocrine features. The most common symptom and signs are abdominal pain, acute appendicitis and palpable mass. Additionally, abdominal pain is common in patient on peritoneal dialysis, which may confound the diagnosis in such patient. CASE PRESENTATION: We report a 71- years- old woman on peritoneal dialysis that experienced several episodes of abdominal cramping pain and sterile peritonitis...
February 13, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28190820/pulmonary-neuroendocrine-tumor-in-a-female-wolf-canis-lupus-lupus
#15
Ayako Shiraki, Toshinori Yoshida, Masahi Kawashima, Hirotada Murayama, Rei Nagahara, Nanao Ito, Makoto Shibutani
A 17-year-old female wolf (Canis lupus lupus) had a right lung mass that was adhered to the thoracic cavity. Histopathological examination revealed that the mass consisted of sheets, cord or ribbon-like structures of monotonous, small, cuboidal cells with round, oval or short-spindle nuclei and scant clear cytoplasm, demarcated by a fine fibrovascular stroma. Focal necrosis, congestion and thrombi were observed. Immunohistochemically, the tumor cells diffusely expressed cytokeratin AE1/AE3, and some expressed chromogranin A, neural cell adhesion molecule (CD56) and thyroid transcription factor-1...
February 11, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28190362/unusual-presentation-of-obstructive-jaundice
#16
Alejandra Gordillo Hernández, Ángel Nogales Muñoz, Fernando Oliva Mompeán
Carcinoid tumors of the ampulla of Vater grow slowly and have an excellent prognosis after complete resection of local disease. Histopathological diagnosis is definitive, and the Whipple's procedure is performed as a standard at the present time, although more novel minimally-invasive techniques may be highly useful for selected patients. While tumor size is not a reliable marker of tumor aggression, it is nonetheless related to lymphatic invasion, hence an accurate diagnosis is important if the patient is to be offered the best option available for the treatment of their disease...
February 13, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28183788/prognostic-factors-in-ectopic-cushing-s-syndrome-due-to-neuroendocrine-tumors-a-multicenter-study
#17
Maria Vittoria Davi', Elisa Cosaro, Serena Piacentini, Giuseppe Reimondo, Nora Albiger, Giorgio Arnaldi, Antongiulio Faggiano, Giovanna Mantovani, Nicola Fazio, Alessandro Piovesan, Emanuela Arvat, Franco Grimaldi, Letizia Canu, Massimo Mannelli, Alberto Giacinto Ambrogio, Francesca Pecori Giraldi, Chiara Martini, Andrea Lania, Manuela Albertelli, Diego Ferone, Maria Chiara Zatelli, Davide Campana, Annamaria Colao, Carla Scaroni, Massimo Terzolo, Laura De Marinis, Sara Cingarlini, Rocco Micciolo, Giuseppe Francia
OBJECTIVE: Evidence is limited regarding outcome of patients with ectopic Cushing's syndrome (ECS) due to neuroendocrine tumors (NETs). DESIGN: We assessed the prognostic factors affecting the survival of patients with NETs and ECS. METHODS: Retrospective analysis of clinicopathological features, severity of hormonal syndrome, treatments from a large cohort of patients with NETs and ECS collected from 17 Italian centers. RESULTS: Our series included 110 patients, 58...
April 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28169866/low-grade-neuroendocrine-carcinoma-of-the-skin-primary-cutaneous-carcinoid-tumor-as-a-distinctive-entity-of-cutaneous-neuroendocrine-tumors-a-clinicopathologic-study-of-3-cases-with-literature-review
#18
Keisuke Goto, Takashi Anan, Takashi Nakatsuka, Yo Kaku, Takaki Sakurai, Takaya Fukumoto, Tetsunori Kimura, Arihiro Shibata
There is scarcity of information on primary cutaneous low-grade neoplasms commonly known as carcinoid tumors, owing to their rarity. The authors present 3 cases that were named "low-grade neuroendocrine carcinoma of the skin" (LGNECS). These occurred in the dermis and subcutis of the anterior chest or the inguinal region in the elderly. Histologically, the tumors showed infiltrating proliferation of nests of various sizes, with low-grade neuroendocrine cytologic features but without mucin production. All cases exhibited varying degrees of intraductal tumor components...
February 2, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28166143/an-111in-pentetreotide-positive-sclerosing-pneumocytoma
#19
Giordano Savelli, Claudio Bnà, Claudia Zambelli, Sonia Illuminati, Luke Bonello
A 43-year-old woman had an incidental lung mass identified on shoulder x-ray performed for pain. Contrast-enhanced CT showed a 38-mm mass in the medial segment of the right middle lobe, with features suggestive of carcinoid tumor. A In-pentetreotide scan showed intense uptake; furthermore, fine needle aspiration biopsy yielded neuroendocrine cells confirming the carcinoid hypothesis. However, definitive surgical histology showed a sclerosing pneumocytoma. This could potentially suggest that such rare tumors, with metastatic potential, could respond to somatostatin analogue treatment...
February 3, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28165678/rare-cause-for-hemoptysis-in-an-adolescent-bronchial-capillary-hemangioma
#20
Susanne Hämmerling, Sebastian Becker, Marcus A Mall
Hemoptysis is rare in children and adolescents. We describe an 11-year-old girl who presented with hemoptysis, cough, and exertional dyspnea. Radiologic and bronchoscopic assessment revealed a pedunculated mass in the right main stem bronchus with a ball valve effect. Carcinoid or hemangioma was suspected as cause of the mass. The tumor could be excised bronchoscopically, and histologic examination showed a capillary hemangioma. In the literature, bronchial hemangiomas are described in infants and adults. This case demonstrates that bronchial hemangioma should also be taken into consideration as a cause of hemoptysis in adolescents...
February 6, 2017: Pediatric Pulmonology
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